TreeWAS – Variant ID: rs4908760

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E00-E07 Disorders of thyroid gland	0.000	0.437	0.563
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.443	0.557
E03 Other hypothyroidism	0.000	0.445	0.555
E03.9 Hypothyroidism, unspecified	0.000	0.446	0.554
E07 Other disorders of thyroid	0.000	0.460	0.540
E05.9 Thyrotoxicosis, unspecified	0.000	0.469	0.531
E07.9 Disorder of thyroid, unspecified	0.000	0.480	0.520
E04 Other non-toxic goitre	0.000	0.486	0.514
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.503	0.497
E04.1 Non-toxic single thyroid nodule	0.000	0.530	0.470
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.547	0.453
E04.2 Non-toxic multinodular goitre	0.000	0.554	0.446
E05.8 Other thyrotoxicosis	0.000	0.555	0.444
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.577	0.423
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.579	0.421
E06 Thyroiditis	0.000	0.586	0.414
E07.8 Other specified disorders of thyroid	0.000	0.587	0.413
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.596	0.404
E00 Congenital iodine-deficiency syndrome	0.000	0.596	0.404
E05.5 Thyroid crisis or storm	0.000	0.600	0.400
E05.4 Thyrotoxicosis factitia	0.000	0.600	0.400
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.600	0.400
E03.5 Myxoedema coma	0.000	0.602	0.398
E03.4 Atrophy of thyroid (acquired)	0.000	0.602	0.398
E03.3 Postinfectious hypothyroidism	0.000	0.602	0.398
E07.1 Dyshormogenetic goitre	0.000	0.613	0.387
E07.0 Hypersecretion of calcitonin	0.000	0.613	0.387
E04.0 Non-toxic diffuse goitre	0.000	0.614	0.385
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.618	0.382
E03.8 Other specified hypothyroidism	0.000	0.624	0.376
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.626	0.374
E04.8 Other specified non-toxic goitre	0.000	0.632	0.368
E06.3 Autoimmune thyroiditis	0.000	0.666	0.334
E03.1 Congenital hypothyroidism without goitre	0.000	0.667	0.333
E06.5 Other chronic thyroiditis	0.000	0.671	0.329
E06.4 Drug-induced thyroiditis	0.000	0.703	0.297
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.703	0.297
E06.0 Acute thyroiditis	0.000	0.703	0.297
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.710	0.290
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.710	0.290
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.710	0.290
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.710	0.290
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.710	0.290
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.710	0.290
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.710	0.290
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.710	0.290
E06.1 Subacute thyroiditis	0.000	0.723	0.277
E04.9 Non-toxic goitre, unspecified	0.000	0.773	0.227
E06.9 Thyroiditis, unspecified	0.000	0.774	0.226
I10 Essential (primary) hypertension	0.054	0.946	0.000
I73.9 Peripheral vascular disease, unspecified	0.053	0.947	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.970	0.030
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.028	0.972	0.000
I10-I15 Hypertensive diseases	0.028	0.972	0.000
M06.9 Rheumatoid arthritis, unspecified	0.027	0.973	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.026	0.974	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.025	0.975	0.000
I15 Secondary hypertension	0.025	0.975	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.025	0.975	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.022	0.978	0.000
I13 Hypertensive heart and renal disease	0.021	0.978	0.000
I15.9 Seconday hypertension, unspecified	0.021	0.979	0.000
M06 Other rheumatoid arthritis	0.021	0.979	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.979	0.021
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.021	0.979	0.000
I27.9 Pulmonary heart disease, unspecified	0.021	0.979	0.000
I27 Other pulmonary heart diseases	0.021	0.979	0.000
I73 Other peripheral vascular diseases	0.021	0.979	0.000
I15.1 Hypertension secondary to other renal disorders	0.020	0.980	0.000
I27.2 Other secondary pulmonary hypertension	0.020	0.980	0.000
S42.10 Fracture of scapula (closed)	0.020	0.980	0.000
I11 Hypertensive heart disease	0.019	0.981	0.000
M06.3 Rheumatoid nodule	0.019	0.981	0.000
M06.4 Inflammatory polyarthropathy	0.019	0.981	0.000
M06.34 Rheumatoid nodule (Hand)	0.019	0.981	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.018	0.982	0.000
I15.0 Renovascular hypertension	0.018	0.982	0.000
I15.8 Other secondary hypertension	0.018	0.982	0.000
I27.8 Other specified pulmonary heart diseases	0.018	0.982	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.018	0.982	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.018	0.982	0.000
S42.1 Fracture of scapula	0.018	0.982	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.018	0.982	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.018	0.982	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.017	0.983	0.000
S40-S49 Injuries to the shoulder and upper arm	0.017	0.983	0.000
I77.1 Stricture of artery	0.017	0.983	0.000
I74 Arterial embolism and thrombosis	0.017	0.983	0.000
S42 Fracture of shoulder and upper arm	0.017	0.983	0.000
I15.2 Hypertension secondary to endocrine disorders	0.017	0.983	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.016	0.984	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.016	0.984	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.016	0.984	0.000
I77 Other disorders of arteries and arterioles	0.016	0.984	0.000
I27.0 Primary pulmonary hypertension	0.016	0.984	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.016	0.984	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.016	0.984	0.000
I74.5 Embolism and thrombosis of iliac artery	0.016	0.984	0.000
S43.4 Sprain and strain of shoulder joint	0.016	0.984	0.000
M06.2 Rheumatoid bursitis	0.015	0.984	0.000
M06.1 Adult-onset Still's disease	0.015	0.984	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.015	0.985	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.015	0.985	0.000
I27.1 Kyphoscoliotic heart disease	0.015	0.985	0.000
S43.0 Dislocation of shoulder joint	0.015	0.985	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.015	0.985	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.015	0.985	0.000
S42.0 Fracture of clavicle	0.015	0.985	0.000
M06.0 Seronegative rheumatoid arthritis	0.014	0.985	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.014	0.986	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.014	0.986	0.000
M06.8 Other specified rheumatoid arthritis	0.014	0.986	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.014	0.986	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.014	0.986	0.000
M06.38 Rheumatoid nodule (Other)	0.014	0.986	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.014	0.986	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.014	0.986	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.014	0.986	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.014	0.986	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.014	0.986	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.014	0.986	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.014	0.986	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.014	0.986	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.014	0.986	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.014	0.986	0.000
M06.33 Rheumatoid nodule (Forearm)	0.014	0.986	0.000
S42.4 Fracture of lower end of humerus	0.013	0.986	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.013	0.986	0.000
S41 Open wound of shoulder and upper arm	0.013	0.987	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.013	0.987	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.013	0.987	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.013	0.987	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.013	0.987	0.000
S42.11 Fracture of scapula (open)	0.013	0.987	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.013	0.987	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.013	0.987	0.000
S43.2 Dislocation of sternoclavicular joint	0.013	0.987	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.013	0.987	0.000
S43.1 Dislocation of acromioclavicular joint	0.013	0.987	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.013	0.987	0.000
I77.6 Arteritis, unspecified	0.013	0.987	0.000
S48 Traumatic amputation of shoulder and upper arm	0.013	0.987	0.000
S44 Injury of nerves at shoulder and upper arm level	0.013	0.987	0.000
S47 Crushing injury of shoulder and upper arm	0.013	0.987	0.000
S42.00 Fracture of clavicle (closed)	0.013	0.987	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.013	0.987	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.012	0.987	0.000
I77.2 Rupture of artery	0.012	0.988	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.012	0.988	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.012	0.988	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.012	0.988	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.012	0.988	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.012	0.988	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.012	0.988	0.000
I73.8 Other specified peripheral vascular diseases	0.012	0.988	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.012	0.988	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.012	0.988	0.000
S41.1 Open wound of upper arm	0.012	0.988	0.000
I77.5 Necrosis of artery	0.012	0.988	0.000
I77.4 Coeliac artery compression syndrome	0.012	0.988	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.012	0.988	0.000
I70 Atherosclerosis	0.012	0.988	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.011	0.989	0.000
M06.18 Adult-onset Still's disease (Other)	0.011	0.989	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.011	0.989	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.011	0.989	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.011	0.989	0.000
M06.14 Adult-onset Still's disease (Hand)	0.011	0.989	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.011	0.989	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.011	0.989	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.011	0.989	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.011	0.989	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.011	0.989	0.000
M06.28 Rheumatoid bursitis (Other)	0.011	0.989	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.011	0.989	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.011	0.989	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.011	0.989	0.000
M06.24 Rheumatoid bursitis (Hand)	0.011	0.989	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.011	0.989	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.011	0.989	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.011	0.989	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.011	0.989	0.000
S42.01 Fracture of clavicle (open)	0.011	0.989	0.000
S40 Superficial injury of shoulder and upper arm	0.011	0.989	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.011	0.989	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.011	0.989	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.011	0.989	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.011	0.989	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.011	0.989	0.000
Chapter IX Diseases of the circulatory system	0.011	0.989	0.000
S42.41 Fracture of lower end of humerus (open)	0.011	0.989	0.000
L30.9 Dermatitis, unspecified	0.011	0.989	0.000
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.011	0.989	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.011	0.989	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.011	0.989	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.011	0.989	0.000
I77.0 Arteriovenous fistula, acquired	0.010	0.989	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.010	0.989	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.010	0.989	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.010	0.989	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.010	0.989	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.010	0.989	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.010	0.989	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.010	0.989	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.010	0.989	0.000
S46.3 Injury of muscle and tendon of triceps	0.010	0.989	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.010	0.989	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.010	0.990	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.010	0.990	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.010	0.990	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.010	0.990	0.000
S42.40 Fracture of lower end of humerus (closed)	0.010	0.990	0.000
I74.8 Embolism and thrombosis of other arteries	0.010	0.990	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.010	0.990	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.010	0.990	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.010	0.990	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.010	0.990	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.010	0.990	0.000
I28 Other diseases of pulmonary vessels	0.010	0.990	0.000
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.010	0.990	0.000
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.010	0.990	0.000
S45.3 Injury of superficial vein at shoulder and upper arm level	0.010	0.990	0.000
S45.2 Injury of axillary or brachial vein	0.010	0.990	0.000
S45.1 Injury of brachial artery	0.010	0.990	0.000
S45.0 Injury of axillary artery	0.010	0.990	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.010	0.990	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.010	0.990	0.000
I77.3 Arterial fibromuscular dysplasia	0.010	0.990	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.010	0.990	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.010	0.990	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.009	0.990	0.000
C64-C68 Malignant neoplasms of urinary tract	0.000	0.990	0.010
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.009	0.990	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.009	0.991	0.000
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.009	0.991	0.000
S44.8 Injury of other nerves at shoulder and upper arm level	0.009	0.991	0.000
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.009	0.991	0.000
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.009	0.991	0.000
S44.4 Injury of musculocutaneous nerve	0.009	0.991	0.000
S44.3 Injury of axillary nerve	0.009	0.991	0.000
S44.2 Injury of radial nerve at upper arm level	0.009	0.991	0.000
S44.1 Injury of median nerve at upper arm level	0.009	0.991	0.000
S44.0 Injury of ulnar nerve at upper arm level	0.009	0.991	0.000
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.009	0.991	0.000
S48.1 Traumatic amputation at level between shoulder and elbow	0.009	0.991	0.000
S48.0 Traumatic amputation at shoulder joint	0.009	0.991	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.009	0.991	0.000
I79.1 Aortitis in diseases classified elsewhere	0.009	0.991	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.009	0.991	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.009	0.991	0.000
I12 Hypertensive renal disease	0.009	0.991	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.009	0.991	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.991	0.009
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.000	0.991	0.009
I70.1 Atherosclerosis of renal artery	0.009	0.991	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.009	0.991	0.000
I77.8 Other specified disorders of arteries and arterioles	0.009	0.991	0.000
I00-I02 Acute rheumatic fever	0.008	0.991	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.008	0.991	0.000
S42.2 Fracture of upper end of humerus	0.008	0.991	0.000
I70.8 Atherosclerosis of other arteries	0.008	0.992	0.000
D33.3 Cranial nerves	0.008	0.992	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.008	0.992	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.008	0.992	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.008	0.992	0.000
C65 Malignant neoplasm of renal pelvis	0.000	0.992	0.008
I70.9 Generalised and unspecified atherosclerosis	0.008	0.992	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.008	0.992	0.000
I28.8 Other specified diseases of pulmonary vessels	0.008	0.992	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.007	0.992	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.008	0.992	0.000
I70.0 Atherosclerosis of aorta	0.008	0.992	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.008	0.992	0.000
S40.0 Contusion of shoulder and upper arm	0.007	0.992	0.000
I28.1 Aneurysm of pulmonary artery	0.007	0.993	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.007	0.993	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.993	0.007
S42.3 Fracture of shaft of humerus	0.007	0.993	0.000
S41.0 Open wound of shoulder	0.007	0.993	0.000
I31.3 Pericardial effusion (noninflammatory)	0.000	0.993	0.007
E28.2 Polycystic ovarian syndrome	0.000	0.993	0.007
I28.0 Arteriovenous fistula of pulmonary vessels	0.007	0.993	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.000	0.993	0.007
I99 Other and unspecified disorders of circulatory system	0.007	0.993	0.000
C66 Malignant neoplasm of ureter	0.000	0.993	0.007
I70.10 Atherosclerosis of renal artery (without gangrene)	0.007	0.993	0.000
I00 Rheumatic fever without mention of heart involvement	0.007	0.993	0.000
E40-E46 Malnutrition	0.000	0.993	0.007
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.007	0.993	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.006	0.993	0.000
S42.21 Fracture of upper end of humerus (open)	0.006	0.993	0.000
C67.4 Posterior wall of bladder	0.000	0.993	0.006
I95.2 Hypotension due to drugs	0.006	0.994	0.000
I02 Rheumatic chorea	0.006	0.994	0.000
I01 Rheumatic fever with heart involvement	0.006	0.994	0.000
E16.1 Other hypoglycaemia	0.000	0.994	0.006
I70.81 Atherosclerosis of other arteries (with gangrene)	0.006	0.994	0.000
E28 Ovarian dysfunction	0.000	0.994	0.006
E16 Other disorders of pancreatic internal secretion	0.000	0.994	0.006
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.006	0.994	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.006	0.994	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.006	0.994	0.000
F05.9 Delirium, unspecified	0.000	0.994	0.006
C67 Malignant neoplasm of bladder	0.000	0.994	0.006
E24.9 Cushing's syndrome, unspecified	0.000	0.994	0.006
I78 Diseases of capillaries	0.006	0.994	0.000
E24 Cushing's syndrome	0.000	0.994	0.006
L30 Other dermatitis	0.006	0.994	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.994	0.006
I70.01 Atherosclerosis of aorta (with gangrene)	0.006	0.994	0.000
H05.2 Exophthalmic conditions	0.000	0.994	0.006
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.005	0.994	0.000
C68.9 Urinary organ, unspecified	0.000	0.994	0.006
E15 Nondiabetic hypoglycaemic coma	0.000	0.994	0.005
C67.6 Ureteric orifice	0.000	0.994	0.006
C68.8 Overlapping lesion of urinary organs	0.000	0.995	0.005
C68.1 Paraurethral glands	0.000	0.995	0.005
I98 Other disorders of circulatory system in diseases classified elsewhere	0.005	0.995	0.000
H05 Disorders of orbit	0.000	0.995	0.005
E34.0 Carcinoid syndrome	0.000	0.995	0.005
D21 Other benign neoplasms of connective and other soft tissue	0.005	0.995	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.995	0.005
E46 Unspecified protein-energy malnutrition	0.000	0.995	0.005
E34 Other endocrine disorders	0.000	0.995	0.005
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.995	0.005
E45 Retarded development following protein-energy malnutrition	0.000	0.995	0.005
E43 Unspecified severe protein-energy malnutrition	0.000	0.995	0.005
E42 Marasmic kwashiorkor	0.000	0.995	0.005
E41 Nutritional marasmus	0.000	0.995	0.005
E40 Kwashiorkor	0.000	0.995	0.005
M14.6 Neuropathic arthropathy	0.005	0.995	0.000
L30.8 Other specified dermatitis	0.005	0.995	0.000
H05.0 Acute inflammation of orbit	0.000	0.995	0.005
H05.4 Enophthalmos	0.000	0.995	0.005
E24.2 Drug-induced Cushing's syndrome	0.000	0.995	0.005
M14 Arthropathies in other diseases classified elsewhere	0.005	0.995	0.000
C68.0 Urethra	0.000	0.995	0.005
D21.2 Connective and other soft tissue of lower limb, including hip	0.005	0.995	0.000
I83 Varicose veins of lower extremities	0.000	0.995	0.005
I01.9 Acute rheumatic heart disease, unspecified	0.005	0.995	0.000
I01.8 Other acute rheumatic heart disease	0.005	0.995	0.000
I01.2 Acute rheumatic myocarditis	0.005	0.995	0.000
I01.1 Acute rheumatic endocarditis	0.005	0.995	0.000
I01.0 Acute rheumatic pericarditis	0.005	0.995	0.000
I02.9 Rheumatic chorea without heart involvement	0.005	0.995	0.000
I02.0 Rheumatic chorea with heart involvement	0.005	0.995	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.995	0.005
E28.8 Other ovarian dysfunction	0.000	0.995	0.005
E28.1 Androgen excess	0.000	0.995	0.005
E28.0 Oestrogen excess	0.000	0.995	0.005
K70.9 Alcoholic liver disease, unspecified	0.005	0.995	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.995	0.005
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.995	0.005
E16.4 Abnormal secretion of gastrin	0.000	0.995	0.005
E16.3 Increased secretion of glucagon	0.000	0.995	0.005
E28.3 Primary ovarian failure	0.000	0.995	0.005
I70.00 Atherosclerosis of aorta (without gangrene)	0.005	0.995	0.000
H05.9 Disorder of orbit, unspecified	0.000	0.995	0.005
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.005	0.995	0.000
M05-M14 Inflammatory polyarthropathies	0.005	0.995	0.000
E24.8 Other Cushing's syndrome	0.000	0.995	0.005
E31 Polyglandular dysfunction	0.000	0.995	0.005
W55.0 Home	0.005	0.995	0.000
E25 Adrenogenital disorders	0.000	0.995	0.005
C44.5 Skin of trunk	0.005	0.995	0.000
C67.1 Dome of bladder	0.000	0.995	0.005
F79.9 Unspecified mental retardation (Without mention of impairment of behaviour)	0.000	0.995	0.005
I78.9 Disease of capillaries, unspecified	0.004	0.995	0.000
C67.7 Urachus	0.000	0.995	0.004
D21.5 Connective and other soft tissue of pelvis	0.005	0.995	0.000
L30.1 Dyshidrosis [pompholyx]	0.004	0.995	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.995	0.004
E24.3 Ectopic ACTH syndrome	0.000	0.995	0.004
E24.1 Nelson's syndrome	0.000	0.995	0.004
L30.3 Infective dermatitis	0.004	0.995	0.000
L30.5 Pityriasis alba	0.004	0.995	0.000
L30.2 Cutaneous autosensitisation	0.004	0.995	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.995	0.004
E30 Disorders of puberty, not elsewhere classified	0.000	0.995	0.004
C67.0 Trigone of bladder	0.000	0.996	0.004
L30.0 Nummular dermatitis	0.004	0.996	0.000
H01.0 Blepharitis	0.000	0.996	0.004
M14.2 Diabetic arthropathy	0.004	0.996	0.000
I26 Pulmonary embolism	0.004	0.996	0.000
I95 Hypotension	0.004	0.996	0.000
E32 Diseases of thymus	0.000	0.996	0.004
E50-E64 Other nutritional deficiencies	0.000	0.996	0.004
S42.31 Fracture of shaft of humerus (open)	0.004	0.996	0.000
E26 Hyperaldosteronism	0.000	0.996	0.004
I12.0 Hypertensive renal disease with renal failure	0.004	0.996	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.004	0.996	0.000
H05.8 Other disorders of orbit	0.000	0.996	0.004
E24.0 Pituitary-dependent Cushing's disease	0.000	0.996	0.004
C83.0 Small cell (diffuse)	0.004	0.996	0.000
E34.3 Short stature, not elsewhere classified	0.000	0.996	0.004
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.004	0.996	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.004	0.996	0.000
L30.4 Erythema intertrigo	0.004	0.996	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.004	0.996	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
I98.0 Cardiovascular syphilis	0.004	0.996	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.000	0.996	0.004
H05.3 Deformity of orbit	0.000	0.996	0.004
N39.9 Disorder of urinary system, unspecified	0.000	0.996	0.004
C67.8 Overlapping lesion of bladder	0.000	0.996	0.004
W55 Bitten or struck by other mammals	0.004	0.996	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.004	0.996	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.004	0.996	0.000
E34.5 Androgen resistance syndrome	0.000	0.996	0.004
E34.4 Constitutional tall stature	0.000	0.996	0.004
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.996	0.004
E34.1 Other hypersecretion of intestinal hormones	0.000	0.996	0.004
E44.1 Mild protein-energy malnutrition	0.000	0.996	0.004
E44.0 Moderate protein-energy malnutrition	0.000	0.996	0.004
M05 Seropositive rheumatoid arthritis	0.004	0.996	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.004	0.996	0.000
I78.8 Other diseases of capillaries	0.004	0.996	0.000
W55.8 Other specified place	0.004	0.996	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.004	0.996	0.000
E20 Hypoparathyroidism	0.000	0.996	0.004
E22 Hyperfunction of pituitary gland	0.000	0.996	0.004
D21.6 Connective and other soft tissue of trunk, unspecified	0.004	0.996	0.000
E31.0 Autoimmune polyglandular failure	0.000	0.996	0.004
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.004	0.996	0.000
M14.4 Arthropathy in amyloidosis	0.004	0.996	0.000
M14.3 Lipoid dermatoarthritis	0.004	0.996	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.004	0.996	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.004	0.996	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.996	0.004
E61 Deficiency of other nutrient elements	0.000	0.996	0.004
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.996	0.004
C67.5 Bladder neck	0.000	0.996	0.004
E61.1 Iron deficiency	0.000	0.996	0.004
I97.2 Postmastectomy lymphoedema syndrome	0.004	0.996	0.000
H05.1 Chronic inflammatory disorders of orbit	0.000	0.996	0.004
W55.7 Farm	0.004	0.996	0.000
D33.4 Spinal cord	0.004	0.996	0.000
T79.7 Traumatic subcutaneous emphysema	0.000	0.996	0.004
I97.0 Postcardiotomy syndrome	0.003	0.996	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.004	0.996	0.000
D21.9 Connective and other soft tissue, unspecified	0.004	0.996	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.004	0.996	0.000
E25.9 Adrenogenital disorder, unspecified	0.000	0.996	0.003
E25.8 Other adrenogenital disorders	0.000	0.996	0.003
E31.9 Polyglandular dysfunction, unspecified	0.000	0.996	0.003
E31.8 Other polyglandular dysfunction	0.000	0.996	0.003
E31.1 Polyglandular hyperfunction	0.000	0.996	0.003
M08 Juvenile arthritis	0.003	0.996	0.000
C67.3 Anterior wall of bladder	0.000	0.996	0.003
D21.3 Connective and other soft tissue of thorax	0.003	0.996	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.996	0.004
I71 Aortic aneurysm and dissection	0.004	0.996	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.996	0.003
E30.9 Disorder of puberty, unspecified	0.000	0.996	0.003
E30.8 Other disorders of puberty	0.000	0.996	0.003
E30.1 Precocious puberty	0.000	0.996	0.003
E30.0 Delayed puberty	0.000	0.996	0.003
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.996	0.003
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.996	0.003
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.996	0.003
M14.8 Arthropathies in other specified diseases classified elsewhere	0.003	0.997	0.000
I42.9 Cardiomyopathy, unspecified	0.000	0.997	0.003
E58 Dietary calcium deficiency	0.000	0.997	0.003
M05.0 Felty's syndrome	0.003	0.997	0.000
D21.4 Connective and other soft tissue of abdomen	0.003	0.997	0.000
H66.9 Otitis media, unspecified	0.003	0.997	0.000
Z83.7 Family history of diseases of the digestive system	0.003	0.997	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.997	0.003
E50 Vitamin A deficiency	0.000	0.997	0.003
E60 Dietary zinc deficiency	0.000	0.997	0.003
E59 Dietary selenium deficiency	0.000	0.997	0.003
E54 Ascorbic acid deficiency	0.000	0.997	0.003
E52 Niacin deficiency [pellagra]	0.000	0.997	0.003
E21.0 Primary hyperparathyroidism	0.000	0.997	0.003
E32.8 Other diseases of thymus	0.000	0.997	0.003
E32.1 Abscess of thymus	0.000	0.997	0.003
E32.0 Persistent hyperplasia of thymus	0.000	0.997	0.003
E22.0 Acromegaly and pituitary gigantism	0.000	0.997	0.003
E51 Thiamine deficiency	0.000	0.997	0.003
E26.8 Other hyperaldosteronism	0.000	0.997	0.003
E26.1 Secondary hyperaldosteronism	0.000	0.997	0.003
M05.1 Rheumatoid lung disease	0.003	0.997	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.003	0.997	0.000
M05.8 Other seropositive rheumatoid arthritis	0.003	0.997	0.000
E21.4 Other specified disorders of parathyroid gland	0.000	0.997	0.003
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.997	0.003
E26.0 Primary hyperaldosteronism	0.000	0.997	0.003
E32.9 Disease of thymus, unspecified	0.000	0.997	0.003
W55.9 Unspecified place	0.003	0.997	0.000
W55.5 Trade and service area	0.003	0.997	0.000
W55.6 Industrial and construction area	0.003	0.997	0.000
W55.3 Sports and athletics area	0.003	0.997	0.000
W55.2 School, other institution and public administrative area	0.003	0.997	0.000
W55.1 Residential institution	0.003	0.997	0.000
D33.9 Central nervous system, unspecified	0.003	0.997	0.000
D33.7 Other specified parts of central nervous system	0.003	0.997	0.000
D33.1 Brain, infratentorial	0.003	0.997	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.997	0.003
W55.4 Street and highway	0.003	0.997	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations