TreeWAS – Variant ID: rs4929923

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.561	0.439
O42 Premature rupture of membranes	0.000	0.582	0.418
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.000	0.600	0.400
O40 Polyhydramnios	0.000	0.612	0.388
O47 False labour	0.000	0.624	0.376
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.627	0.373
O35 Maternal care for known or suspected foetal abnormality and damage	0.000	0.637	0.363
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.648	0.352
H36.0 Diabetic retinopathy	0.344	0.656	0.000
H36 Retinal disorders in diseases classified elsewhere	0.336	0.664	0.000
O45 Premature separation of placenta [abruptio placentae]	0.000	0.666	0.334
O36 Maternal care for other known or suspected foetal problems	0.000	0.669	0.331
H30-H36 Disorders of choroid and retina	0.331	0.669	0.000
O41 Other disorders of amniotic fluid and membranes	0.000	0.670	0.330
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.000	0.671	0.329
H31 Other disorders of choroid	0.325	0.675	0.000
H34 Retinal vascular occlusions	0.320	0.680	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.683	0.316
O36.8 Maternal care for other specified foetal problems	0.000	0.688	0.312
O47.0 False labour before 37 completed weeks of gestation	0.000	0.692	0.308
H34.8 Other retinal vascular occlusions	0.303	0.697	0.000
O33 Maternal care for known or suspected disproportion	0.000	0.700	0.300
H31.8 Other specified disorders of choroid	0.299	0.701	0.000
H31.0 Chorioretinal scars	0.296	0.704	0.000
O36.5 Maternal care for poor foetal growth	0.000	0.712	0.288
O45.9 Premature separation of placenta, unspecified	0.000	0.713	0.287
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.000	0.715	0.285
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.722	0.278
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.000	0.722	0.278
H34.2 Other retinal artery occlusions	0.275	0.725	0.000
H35 Other retinal disorders	0.270	0.730	0.000
O31 Complications specific to multiple gestation	0.000	0.738	0.262
O47.9 False labour, unspecified	0.000	0.740	0.260
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.000	0.740	0.260
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.000	0.740	0.260
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.000	0.740	0.260
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.000	0.740	0.260
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.000	0.740	0.260
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.000	0.740	0.260
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.000	0.743	0.257
H31.3 Choroidal haemorrhage and rupture	0.257	0.743	0.000
O41.1 Infection of amniotic sac and membranes	0.000	0.743	0.257
O43 Placental disorders	0.000	0.746	0.254
O30 Multiple gestation	0.000	0.749	0.251
H35.4 Peripheral retinal degeneration	0.251	0.749	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.000	0.751	0.249
H35.9 Retinal disorder, unspecified	0.249	0.751	0.000
O44 Placenta praevia	0.000	0.752	0.248
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.752	0.248
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.752	0.248
H31.1 Choroidal degeneration	0.243	0.757	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.241	0.759	0.000
H34.1 Central retinal artery occlusion	0.241	0.759	0.000
O45.8 Other premature separation of placenta	0.000	0.760	0.240
O45.0 Premature separation of placenta with coagulation defect	0.000	0.760	0.240
H31.9 Disorder of choroid, unspecified	0.239	0.761	0.000
O33.9 Maternal care for disproportion, unspecified	0.000	0.761	0.239
O36.4 Maternal care for intra-uterine death	0.000	0.762	0.238
O36.2 Maternal care for hydrops foetalis	0.000	0.762	0.238
H32 Chorioretinal disorders in diseases classified elsewhere	0.237	0.763	0.000
H31.4 Choroidal detachment	0.233	0.767	0.000
H31.2 Hereditary choroidal dystrophy	0.233	0.767	0.000
H30 Chorioretinal inflammation	0.232	0.768	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.769	0.231
H34.0 Transient retinal artery occlusion	0.229	0.771	0.000
O43.8 Other placental disorders	0.000	0.781	0.219
H35.6 Retinal haemorrhage	0.218	0.782	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.783	0.217
O36.1 Maternal care for other isoimmunisation	0.000	0.784	0.216
O33.8 Maternal care for disproportion of other origin	0.000	0.785	0.215
O33.7 Maternal care for disproportion due to other foetal deformities	0.000	0.785	0.215
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.000	0.785	0.215
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.000	0.785	0.215
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.000	0.785	0.215
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.000	0.785	0.215
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.000	0.785	0.215
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.000	0.785	0.215
H34.9 Retinal vascular occlusion, unspecified	0.213	0.786	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.000	0.798	0.202
O34.4 Maternal care for other abnormalities of cervix	0.000	0.800	0.200
O34.2 Maternal care due to uterine scar from previous surgery	0.000	0.801	0.199
O34.8 Maternal care for other abnormalities of pelvic organs	0.000	0.804	0.196
H35.1 Retinopathy of prematurity	0.194	0.806	0.000
O34.1 Maternal care for tumour of corpus uteri	0.000	0.806	0.194
H35.7 Separation of retinal layers	0.188	0.812	0.000
O31.0 Papyraceous foetus	0.000	0.812	0.188
O44.1 Placenta praevia with haemorrhage	0.000	0.813	0.187
O36.9 Maternal care for foetal problem, unspecified	0.000	0.813	0.186
O31.8 Other complications specific to multiple gestation	0.000	0.817	0.183
O43.2 Morbidly adherent placenta	0.000	0.818	0.182
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.000	0.819	0.181
O36.6 Maternal care for excessive foetal growth	0.000	0.819	0.181
O30.9 Multiple gestation, unspecified	0.000	0.820	0.180
O30.8 Other multiple gestation	0.000	0.820	0.180
O30.2 Quadruplet pregnancy	0.000	0.820	0.180
O43.0 Placental transfusion syndromes	0.000	0.820	0.180
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.820	0.180
O41.0 Oligohydramnios	0.000	0.820	0.179
O48 Prolonged pregnancy	0.000	0.822	0.178
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.822	0.178
O31.1 Continuing pregnancy after abortion of one foetus or more	0.000	0.823	0.177
H35.5 Hereditary retinal dystrophy	0.176	0.824	0.000
O30.1 Triplet pregnancy	0.000	0.824	0.176
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.000	0.825	0.175
O34.0 Maternal care for congenital malformation of uterus	0.000	0.825	0.175
H35.2 Other proliferative retinopathy	0.174	0.826	0.000
O34.6 Maternal care for abnormality of vagina	0.000	0.828	0.172
O46.8 Other antepartum haemorrhage	0.000	0.829	0.171
H30.9 Chorioretinal inflammation, unspecified	0.171	0.829	0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.170	0.830	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.170	0.830	0.000
H30.8 Other chorioretinal inflammations	0.166	0.834	0.000
H30.1 Disseminated chorioretinal inflammation	0.166	0.834	0.000
H30.0 Focal chorioretinal inflammation	0.166	0.834	0.000
H35.0 Background retinopathy and retinal vascular changes	0.165	0.835	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.000	0.835	0.164
H30.2 Posterior cyclitis	0.155	0.845	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.000	0.847	0.153
O34.3 Maternal care for cervical incompetence	0.000	0.849	0.150
O30.0 Twin pregnancy	0.000	0.850	0.150
O46.9 Antepartum haemorrhage, unspecified	0.000	0.852	0.148
O43.1 Malformation of placenta	0.000	0.860	0.140
H33 Retinal detachments and breaks	0.127	0.873	0.000
H35.3 Degeneration of macula and posterior pole	0.127	0.873	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.877	0.123
O43.9 Placental disorder, unspecified	0.001	0.877	0.122
O32.3 Maternal care for face, brow and chin presentation	0.000	0.883	0.117
O32.6 Maternal care for compound presentation	0.000	0.883	0.117
O32.9 Maternal care for malpresentation of foetus, unspecified	0.000	0.884	0.116
O32.4 Maternal care for high head at term	0.000	0.885	0.115
H33.4 Traction detachment of retina	0.114	0.886	0.000
O32.0 Maternal care for unstable lie	0.000	0.888	0.112
O42.9 Premature rupture of membranes, unspecified	0.000	0.889	0.111
O32.8 Maternal care for other malpresentation of foetus	0.000	0.896	0.104
O32.2 Maternal care for transverse and oblique lie	0.000	0.899	0.101
H33.0 Retinal detachment with retinal break	0.098	0.902	0.000
H33.1 Retinoschisis and retinal cysts	0.078	0.922	0.000
H33.5 Other retinal detachments	0.077	0.923	0.000
H35.8 Other specified retinal disorders	0.077	0.923	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.001	0.937	0.061
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.000	0.939	0.061
N48.6 Balanitis xerotica obliterans	0.053	0.947	0.000
N48 Other disorders of penis	0.049	0.951	0.000
N48.4 Impotence of organic origin	0.048	0.952	0.000
H33.2 Serous retinal detachment	0.046	0.954	0.000
N48.9 Disorder of penis, unspecified	0.046	0.954	0.000
C71 Malignant neoplasm of brain	0.044	0.956	0.000
C71.9 Brain, unspecified	0.043	0.957	0.000
N48.1 Balanoposthitis	0.042	0.958	0.000
N48.3 Priapism	0.042	0.958	0.000
C71.0 Cerebrum, except lobes and ventricles	0.040	0.960	0.000
C71.4 Occipital lobe	0.039	0.961	0.000
N48.0 Leukoplakia of penis	0.037	0.963	0.000
C71.1 Frontal lobe	0.037	0.963	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.036	0.964	0.000
C71.3 Parietal lobe	0.036	0.964	0.000
C69 Malignant neoplasm of eye and adnexa	0.036	0.964	0.000
C71.6 Cerebellum	0.035	0.965	0.000
C71.5 Cerebral ventricle	0.035	0.965	0.000
C69.3 Choroid	0.035	0.965	0.000
N48.5 Ulcer of penis	0.032	0.967	0.000
C71.2 Temporal lobe	0.029	0.970	0.000
C69.9 Eye, unspecified	0.029	0.971	0.000
C71.7 Brain stem	0.029	0.971	0.000
C70 Malignant neoplasm of meninges	0.027	0.973	0.000
C69.6 Orbit	0.027	0.973	0.000
C69.4 Ciliary body	0.027	0.973	0.000
C69.0 Conjunctiva	0.027	0.973	0.000
E11.3 With ophthalmic complications	0.027	0.973	0.000
C71.8 Overlapping lesion of brain	0.026	0.974	0.000
C69.8 Overlapping lesion of eye and adnexa	0.026	0.974	0.000
C69.5 Lachrymal gland and duct	0.026	0.974	0.000
C69.1 Cornea	0.026	0.974	0.000
O32.1 Maternal care for breech presentation	0.000	0.974	0.026
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.026	0.974	0.000
N48.2 Other inflammatory disorders of penis	0.025	0.975	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.976	0.024
C69.2 Retina	0.023	0.977	0.000
C78.2 Secondary malignant neoplasm of pleura	0.000	0.978	0.022
C70.0 Cerebral meninges	0.021	0.979	0.000
C70.9 Meninges, unspecified	0.020	0.980	0.000
C70.1 Spinal meninges	0.020	0.980	0.000
E11 Non-insulin-dependent diabetes mellitus	0.020	0.980	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.000	0.981	0.019
E11.2 With renal complications	0.019	0.981	0.000
C72.9 Central nervous system, unspecified	0.018	0.981	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.018	0.981	0.000
C72.5 Other and unspecified cranial nerves	0.018	0.981	0.000
C72.4 Acoustic nerve	0.018	0.981	0.000
C72.3 Optic nerve	0.018	0.981	0.000
C72.2 Olfactory nerve	0.018	0.981	0.000
C72.1 Cauda equina	0.018	0.981	0.000
C72.0 Spinal cord	0.018	0.982	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.982	0.018
O23 Infections of genito-urinary tract in pregnancy	0.000	0.983	0.017
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.983	0.017
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.983	0.017
H81.0 Meniere's disease	0.017	0.983	0.000
E11.4 With neurological complications	0.016	0.984	0.000
E11.6 With other specified complications	0.015	0.984	0.000
E11.7 With multiple complications	0.015	0.985	0.000
E11.0 With coma	0.015	0.985	0.000
H33.3 Retinal breaks without detachment	0.015	0.985	0.000
O22 Venous complications in pregnancy	0.000	0.985	0.015
O28 Abnormal findings on antenatal screening of mother	0.000	0.986	0.014
O23.5 Infections of the genital tract in pregnancy	0.000	0.986	0.014
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.986	0.014
E11.8 With unspecified complications	0.014	0.986	0.000
O22.4 Haemorrhoids in pregnancy	0.000	0.986	0.014
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.986	0.014
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.000	0.986	0.014
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.986	0.014
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.987	0.013
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.987	0.013
O29 Complications of anaesthesia during pregnancy	0.000	0.987	0.013
O25 Malnutrition in pregnancy	0.000	0.987	0.013
E11.1 With ketoacidosis	0.013	0.987	0.000
E11.5 With peripheral circulatory complications	0.013	0.987	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.000	0.987	0.013
O23.2 Infections of urethra in pregnancy	0.000	0.987	0.013
O23.1 Infections of bladder in pregnancy	0.000	0.987	0.013
O21 Excessive vomiting in pregnancy	0.000	0.987	0.012
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O97 Death from sequelae of direct obstetric causes	0.000	0.988	0.012
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.000	0.988	0.012
O95 Obstetric death of unspecified cause	0.000	0.988	0.012
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.000	0.988	0.012
H81 Disorders of vestibular function	0.012	0.988	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O23.0 Infections of kidney in pregnancy	0.000	0.989	0.011
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.989	0.011
O26.0 Excessive weight gain in pregnancy	0.000	0.989	0.011
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.000	0.989	0.011
O21.0 Mild hyperemesis gravidarum	0.000	0.989	0.011
O22.9 Venous complication in pregnancy, unspecified	0.000	0.989	0.011
O22.8 Other venous complications in pregnancy	0.000	0.989	0.011
O22.5 Cerebral venous thrombosis in pregnancy	0.000	0.989	0.011
O22.2 Superficial thrombophlebitis in pregnancy	0.000	0.989	0.011
H81.1 Benign paroxysmal vertigo	0.011	0.989	0.000
O26.5 Maternal hypotension syndrome	0.000	0.989	0.011
O22.3 Deep phlebothrombosis in pregnancy	0.000	0.989	0.011
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.989	0.011
O28.8 Other abnormal findings on antenatal screening of mother	0.000	0.989	0.010
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.000	0.989	0.010
O28.4 Abnormal radiological finding on antenatal screening of mother	0.000	0.989	0.010
O28.2 Abnormal cytological finding on antenatal screening of mother	0.000	0.989	0.010
O26.2 Pregnancy care of habitual aborter	0.000	0.989	0.011
H81.9 Disorder of vestibular function, unspecified	0.010	0.990	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.000	0.990	0.010
O24 Diabetes mellitus in pregnancy	0.000	0.990	0.010
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.990	0.010
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.990	0.010
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.000	0.990	0.010
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.000	0.990	0.010
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.000	0.990	0.010
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.000	0.990	0.010
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.000	0.990	0.010
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.000	0.990	0.010
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.000	0.990	0.010
O22.0 Varicose veins of lower extremity in pregnancy	0.000	0.990	0.010
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.000	0.990	0.010
O26.4 Herpes gestationis	0.000	0.990	0.010
O26.1 Low weight gain in pregnancy	0.000	0.990	0.010
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.000	0.990	0.010
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.990	0.010
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.990	0.010
O22.1 Genital varices in pregnancy	0.000	0.990	0.009
O03.4 Incomplete, without complication	0.000	0.990	0.010
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.000	0.990	0.009
O29.8 Other complications of anaesthesia during pregnancy	0.000	0.990	0.009
O29.6 Failed or difficult intubation during pregnancy	0.000	0.990	0.009
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.000	0.990	0.009
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.000	0.990	0.009
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.000	0.990	0.009
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.000	0.990	0.009
O29.1 Cardiac complications of anaesthesia during pregnancy	0.000	0.990	0.009
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.000	0.990	0.009
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.000	0.990	0.009
O28.0 Abnormal haematological finding on antenatal screening of mother	0.000	0.991	0.009
O00-O08 Pregnancy with abortive outcome	0.000	0.991	0.009
O26.8 Other specified pregnancy-related conditions	0.000	0.991	0.009
O96.9 Death from unspecified obstetric cause	0.000	0.991	0.009
O96.1 Death from indirect obstetric cause	0.000	0.991	0.009
O96.0 Death from direct obstetric cause	0.000	0.991	0.009
O97.9 Death from sequelae of obstetric cause, unspecified	0.000	0.991	0.009
O97.1 Death from sequelae of indirect obstetric cause	0.000	0.991	0.009
O97.0 Death from sequelae of direct obstetric cause	0.000	0.991	0.009
H81.2 Vestibular neuronitis	0.009	0.991	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.000	0.991	0.009
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.991	0.009
O21.2 Late vomiting of pregnancy	0.000	0.991	0.008
O03 Spontaneous abortion	0.000	0.991	0.009
H81.4 Vertigo of central origin	0.008	0.991	0.000
E11.9 Without complications	0.008	0.992	0.000
O21.9 Vomiting of pregnancy, unspecified	0.000	0.992	0.008
H81.3 Other peripheral vertigo	0.008	0.992	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.992	0.007
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.992	0.007
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.992	0.007
H81.8 Other disorders of vestibular function	0.007	0.992	0.000
H40.9 Glaucoma, unspecified	0.008	0.992	0.000
H61.0 Perichondritis of external ear	0.007	0.993	0.000
H61 Other disorders of external ear	0.007	0.993	0.000
K82.4 Cholesterolosis of gallbladder	0.007	0.993	0.000
O21.8 Other vomiting complicating pregnancy	0.000	0.993	0.007
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.993	0.007
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.993	0.007
D13.2 Duodenum	0.007	0.993	0.000
O20 Haemorrhage in early pregnancy	0.000	0.993	0.007
O06 Unspecified abortion	0.000	0.993	0.007
O05 Other abortion	0.000	0.993	0.007
O08 Complications following abortion and ectopic and molar pregnancy	0.000	0.993	0.007
O07 Failed attempted abortion	0.000	0.993	0.007
O26.9 Pregnancy-related condition, unspecified	0.000	0.993	0.007
N83.3 Acquired atrophy of ovary and Fallopian tube	0.000	0.993	0.007
O01 Hydatidiform mole	0.000	0.993	0.007
H80-H83 Diseases of inner ear	0.007	0.993	0.000
H60-H62 Diseases of external ear	0.007	0.993	0.000
O03.7 Complete or unspecified, complicated by embolism	0.000	0.994	0.006
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.994	0.006
O03.2 Incomplete, complicated by embolism	0.000	0.994	0.006
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.994	0.006
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.994	0.006
H61.9 Disorder of external ear, unspecified	0.006	0.994	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.000	0.994	0.006
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.994	0.006
H61.8 Other specified disorders of external ear	0.006	0.994	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.006	0.994	0.000
H61.2 Impacted cerumen	0.006	0.994	0.000
N48.8 Other specified disorders of penis	0.006	0.994	0.000
T14.0 Superficial injury of unspecified body region	0.000	0.994	0.006
O20.8 Other haemorrhage in early pregnancy	0.000	0.994	0.006
H60 Otitis externa	0.006	0.994	0.000
H60.9 Otitis externa, unspecified	0.006	0.994	0.000
O80-O84 Delivery	0.000	0.994	0.006
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.994	0.006
O03.3 Incomplete, with other and unspecified complications	0.000	0.994	0.005
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.994	0.005
H62 Disorders of external ear in diseases classified elsewhere	0.005	0.994	0.000
O15 Eclampsia	0.000	0.994	0.005
H61.3 Acquired stenosis of external ear canal	0.005	0.994	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.995	0.005
O04 Medical abortion	0.000	0.995	0.005
O00 Ectopic pregnancy	0.000	0.995	0.005
O05.9 Complete or unspecified, without complication	0.000	0.995	0.005
O05.8 Complete or unspecified, with other and unspecified complications	0.000	0.995	0.005
O05.7 Complete or unspecified, complicated by embolism	0.000	0.995	0.005
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.995	0.005
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.995	0.005
O05.4 Incomplete, without complication	0.000	0.995	0.005
O05.3 Incomplete, with other and unspecified complications	0.000	0.995	0.005
O05.2 Incomplete, complicated by embolism	0.000	0.995	0.005
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.995	0.005
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.995	0.005
O06.9 Complete or unspecified, without complication	0.000	0.995	0.005
O06.8 Complete or unspecified, with other and unspecified complications	0.000	0.995	0.005
O06.7 Complete or unspecified, complicated by embolism	0.000	0.995	0.005
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.995	0.005
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.995	0.005
O06.4 Incomplete, without complication	0.000	0.995	0.005
O06.3 Incomplete, with other and unspecified complications	0.000	0.995	0.005
O06.2 Incomplete, complicated by embolism	0.000	0.995	0.005
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.995	0.005
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.995	0.005
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.000	0.995	0.005
O01.9 Hydatidiform mole, unspecified	0.000	0.995	0.005
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.000	0.995	0.005
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.000	0.995	0.005
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.000	0.995	0.005
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.000	0.995	0.005
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.000	0.995	0.005
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.000	0.995	0.005
O08.3 Shock following abortion and ectopic and molar pregnancy	0.000	0.995	0.005
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.000	0.995	0.005
O07.9 Other and unspecified failed attempted abortion, without complication	0.000	0.995	0.005
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.000	0.995	0.005
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.000	0.995	0.005
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.000	0.995	0.005
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.000	0.995	0.005
O07.3 Failed medical abortion, with other and unspecified complications	0.000	0.995	0.005
O07.2 Failed medical abortion, complicated by embolism	0.000	0.995	0.005
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.000	0.995	0.005
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.000	0.995	0.005
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.995	0.005
H40.2 Primary angle-closure glaucoma	0.005	0.995	0.000
H40.1 Primary open-angle glaucoma	0.005	0.995	0.000
O01.1 Incomplete and partial hydatidiform mole	0.000	0.995	0.005
O07.4 Failed medical abortion, without complication	0.000	0.995	0.005
H60.3 Other infective otitis externa	0.005	0.995	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.005	0.995	0.000
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.000	0.995	0.005
H60.1 Cellulitis of external ear	0.005	0.995	0.000
H40 Glaucoma	0.005	0.995	0.000
H80 Otosclerosis	0.005	0.995	0.000
H61.1 Non-infective disorders of pinna	0.005	0.995	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.005	0.995	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.995	0.004
O14.1 Severe preeclampsia	0.000	0.995	0.005
O01.0 Classical hydatidiform mole	0.000	0.995	0.004
O14.0 Moderate preeclampsia	0.000	0.995	0.005
Chapter VIII Diseases of the ear and mastoid process	0.005	0.995	0.000
O84 Multiple delivery	0.000	0.995	0.004
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.004
H60.0 Abscess of external ear	0.004	0.996	0.000
O14.2 HELLP syndrome	0.000	0.996	0.004
S22.40 Multiple fractures of ribs (closed)	0.000	0.996	0.004
O85-O92 Complications predominantly related to the puerperium	0.000	0.996	0.004
O83 Other assisted single delivery	0.000	0.996	0.004
H60.5 Acute otitis externa, non-infective	0.004	0.996	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.004	0.996	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.004	0.996	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
H62.2 Otitis externa in mycoses	0.004	0.996	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.004	0.996	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O15.9 Eclampsia, unspecified as to time period	0.000	0.996	0.004
O15.2 Eclampsia in the puerperium	0.000	0.996	0.004
O15.1 Eclampsia in labour	0.000	0.996	0.004
O15.0 Eclampsia in pregnancy	0.000	0.996	0.004
O12.1 Gestational proteinuria	0.000	0.996	0.004
K82 Other diseases of gallbladder	0.004	0.996	0.000
O00.9 Ectopic pregnancy, unspecified	0.000	0.996	0.004
O12.0 Gestational oedema	0.000	0.996	0.004
O00.8 Other ectopic pregnancy	0.000	0.996	0.004
O00.2 Ovarian pregnancy	0.000	0.996	0.004
O00.0 Abdominal pregnancy	0.000	0.996	0.004
O04.7 Complete or unspecified, complicated by embolism	0.000	0.996	0.004
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.996	0.004
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.996	0.004
O04.3 Incomplete, with other and unspecified complications	0.000	0.996	0.004
O04.2 Incomplete, complicated by embolism	0.000	0.996	0.004
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.996	0.004
M25.50 Pain in joint (Multiple sites)	0.000	0.996	0.004
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.996	0.004
O04.8 Complete or unspecified, with other and unspecified complications	0.000	0.996	0.004
I78.1 Naevus, nonneoplastic	0.004	0.996	0.000
H40.8 Other glaucoma	0.004	0.996	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.004	0.996	0.000
H60.2 Malignant otitis externa	0.004	0.996	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
H60.8 Other otitis externa	0.004	0.996	0.000
K82.9 Disease of gallbladder, unspecified	0.004	0.996	0.000
O81 Single delivery by forceps and vacuum extractor	0.000	0.996	0.004
H40.6 Glaucoma secondary to drugs	0.004	0.996	0.000
H80.2 Cochlear otosclerosis	0.004	0.996	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.004	0.996	0.000
H80.8 Other otosclerosis	0.004	0.996	0.000
O14.9 Preeclampsia, unspecified	0.000	0.996	0.004
O04.4 Incomplete, without complication	0.000	0.996	0.004
K82.3 Fistula of gallbladder	0.004	0.996	0.000
K82.1 Hydrops of gallbladder	0.004	0.996	0.000
O16 Unspecified maternal hypertension	0.000	0.996	0.004
O84.2 Multiple delivery, all by Caesarean section	0.000	0.996	0.003
O12.2 Gestational oedema with proteinuria	0.000	0.996	0.003
H40.3 Glaucoma secondary to eye trauma	0.004	0.996	0.000
O02 Other abnormal products of conception	0.000	0.996	0.004
J93.9 Pneumothorax, unspecified	0.000	0.996	0.004
H80.9 Otosclerosis, unspecified	0.004	0.996	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.000	0.996	0.004
O84.9 Multiple delivery, unspecified	0.000	0.996	0.003
O84.8 Other multiple delivery	0.000	0.996	0.003
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.000	0.996	0.003
O84.0 Multiple delivery, all spontaneous	0.000	0.996	0.003
L29.9 Pruritus, unspecified	0.004	0.996	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.996	0.004
H40.4 Glaucoma secondary to eye inflammation	0.003	0.996	0.000
K82.0 Obstruction of gallbladder	0.003	0.996	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.003	0.996	0.000
H20.0 Acute and subacute iridocyclitis	0.000	0.996	0.003
O87 Venous complications in the puerperium	0.000	0.997	0.003
H10.9 Conjunctivitis, unspecified	0.000	0.997	0.003
H60.4 Cholesteatoma of external ear	0.003	0.997	0.000
O91 Infections of breast associated with childbirth	0.000	0.997	0.003
O88 Obstetric embolism	0.000	0.997	0.003
O83.9 Assisted single delivery, unspecified	0.000	0.997	0.003
O83.8 Other specified assisted single delivery	0.000	0.997	0.003
O83.4 Destructive operation for delivery	0.000	0.997	0.003
O83.3 Delivery of viable foetus in abdominal pregnancy	0.000	0.997	0.003
O83.2 Other manipulation-assisted delivery	0.000	0.997	0.003
O83.0 Breech extraction	0.000	0.997	0.003
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.997	0.003
K82.2 Perforation of gallbladder	0.003	0.997	0.000
F10.3 Withdrawal state	0.000	0.997	0.003
O20.0 Threatened abortion	0.000	0.997	0.003
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O83.1 Other assisted breech delivery	0.000	0.997	0.003
H20.9 Iridocyclitis, unspecified	0.000	0.997	0.003
H71 Cholesteatoma of middle ear	0.003	0.997	0.000
O89 Complications of anaesthesia during the puerperium	0.000	0.997	0.003
H83 Other diseases of inner ear	0.003	0.997	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.997	0.003
O81.5 Delivery by combination of forceps and vacuum extractor	0.000	0.997	0.003
O81.2 Mid-cavity forceps with rotation	0.000	0.997	0.003
O81.1 Mid-cavity forceps delivery	0.000	0.997	0.003
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations