TreeWAS – Variant ID: rs4929947

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.536	0.464
O42 Premature rupture of membranes	0.000	0.560	0.440
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.000	0.578	0.422
O40 Polyhydramnios	0.000	0.591	0.409
O47 False labour	0.000	0.603	0.397
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.608	0.392
O35 Maternal care for known or suspected foetal abnormality and damage	0.000	0.619	0.381
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.627	0.373
H36.0 Diabetic retinopathy	0.366	0.634	0.000
H36 Retinal disorders in diseases classified elsewhere	0.358	0.642	0.000
H30-H36 Disorders of choroid and retina	0.353	0.647	0.000
O36 Maternal care for other known or suspected foetal problems	0.000	0.647	0.353
O45 Premature separation of placenta [abruptio placentae]	0.000	0.648	0.352
H31 Other disorders of choroid	0.347	0.653	0.000
O41 Other disorders of amniotic fluid and membranes	0.000	0.654	0.346
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.000	0.654	0.346
H34 Retinal vascular occlusions	0.342	0.658	0.000
O36.8 Maternal care for other specified foetal problems	0.000	0.665	0.335
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.666	0.334
H34.8 Other retinal vascular occlusions	0.325	0.675	0.000
O47.0 False labour before 37 completed weeks of gestation	0.000	0.676	0.324
H31.8 Other specified disorders of choroid	0.320	0.680	0.000
O33 Maternal care for known or suspected disproportion	0.000	0.684	0.316
H31.0 Chorioretinal scars	0.316	0.684	0.000
O36.5 Maternal care for poor foetal growth	0.000	0.695	0.305
O45.9 Premature separation of placenta, unspecified	0.000	0.698	0.302
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.000	0.701	0.299
H34.2 Other retinal artery occlusions	0.295	0.705	0.000
H35 Other retinal disorders	0.293	0.707	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.708	0.292
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.000	0.708	0.292
O31 Complications specific to multiple gestation	0.000	0.724	0.276
H31.3 Choroidal haemorrhage and rupture	0.275	0.725	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.000	0.726	0.273
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.000	0.726	0.273
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.000	0.726	0.273
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.000	0.726	0.273
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.000	0.726	0.273
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.000	0.726	0.273
O47.9 False labour, unspecified	0.000	0.727	0.273
H35.4 Peripheral retinal degeneration	0.272	0.728	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.000	0.730	0.270
H35.9 Retinal disorder, unspecified	0.270	0.730	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.730	0.270
O41.1 Infection of amniotic sac and membranes	0.000	0.730	0.270
O43 Placental disorders	0.000	0.734	0.266
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.736	0.264
O30 Multiple gestation	0.000	0.737	0.263
O34 Maternal care for known or suspected abnormality of pelvic organs	0.000	0.739	0.260
O44 Placenta praevia	0.000	0.740	0.260
H31.1 Choroidal degeneration	0.259	0.741	0.000
H34.1 Central retinal artery occlusion	0.258	0.742	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.257	0.743	0.000
H31.9 Disorder of choroid, unspecified	0.256	0.744	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.253	0.746	0.000
O36.2 Maternal care for hydrops foetalis	0.000	0.747	0.253
O36.4 Maternal care for intra-uterine death	0.000	0.747	0.253
O45.8 Other premature separation of placenta	0.000	0.747	0.253
O45.0 Premature separation of placenta with coagulation defect	0.000	0.747	0.253
O33.9 Maternal care for disproportion, unspecified	0.000	0.749	0.251
H31.4 Choroidal detachment	0.249	0.751	0.000
H31.2 Hereditary choroidal dystrophy	0.249	0.751	0.000
H30 Chorioretinal inflammation	0.247	0.752	0.000
H34.0 Transient retinal artery occlusion	0.245	0.755	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.758	0.242
H35.6 Retinal haemorrhage	0.237	0.763	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.769	0.231
O36.1 Maternal care for other isoimmunisation	0.000	0.770	0.230
O43.8 Other placental disorders	0.000	0.771	0.229
H34.9 Retinal vascular occlusion, unspecified	0.229	0.771	0.000
O33.8 Maternal care for disproportion of other origin	0.000	0.773	0.227
O33.7 Maternal care for disproportion due to other foetal deformities	0.000	0.773	0.227
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.000	0.773	0.227
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.000	0.773	0.227
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.000	0.773	0.227
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.000	0.773	0.227
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.000	0.773	0.227
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.000	0.773	0.227
O33.5 Maternal care for disproportion due to unusually large foetus	0.000	0.788	0.212
H35.1 Retinopathy of prematurity	0.210	0.790	0.000
O34.4 Maternal care for other abnormalities of cervix	0.000	0.790	0.210
O34.2 Maternal care due to uterine scar from previous surgery	0.000	0.791	0.209
O34.8 Maternal care for other abnormalities of pelvic organs	0.000	0.795	0.205
H35.7 Separation of retinal layers	0.204	0.796	0.000
O34.1 Maternal care for tumour of corpus uteri	0.000	0.798	0.202
O31.0 Papyraceous foetus	0.000	0.802	0.198
O36.9 Maternal care for foetal problem, unspecified	0.000	0.803	0.197
O44.1 Placenta praevia with haemorrhage	0.000	0.804	0.195
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.806	0.194
O31.8 Other complications specific to multiple gestation	0.000	0.808	0.192
O36.6 Maternal care for excessive foetal growth	0.000	0.808	0.192
H35.5 Hereditary retinal dystrophy	0.191	0.809	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.000	0.809	0.191
O43.2 Morbidly adherent placenta	0.000	0.809	0.190
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.811	0.189
H35.2 Other proliferative retinopathy	0.189	0.811	0.000
O30.9 Multiple gestation, unspecified	0.000	0.811	0.189
O30.8 Other multiple gestation	0.000	0.811	0.189
O30.2 Quadruplet pregnancy	0.000	0.811	0.189
O43.0 Placental transfusion syndromes	0.000	0.812	0.188
O41.0 Oligohydramnios	0.000	0.812	0.187
O31.1 Continuing pregnancy after abortion of one foetus or more	0.000	0.814	0.186
O46.8 Other antepartum haemorrhage	0.000	0.814	0.186
O30.1 Triplet pregnancy	0.000	0.816	0.184
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.000	0.816	0.183
O34.0 Maternal care for congenital malformation of uterus	0.000	0.817	0.183
H30.9 Chorioretinal inflammation, unspecified	0.183	0.817	0.000
O48 Prolonged pregnancy	0.000	0.817	0.183
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.182	0.818	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.182	0.818	0.000
H35.0 Background retinopathy and retinal vascular changes	0.180	0.820	0.000
O34.6 Maternal care for abnormality of vagina	0.000	0.820	0.180
H30.8 Other chorioretinal inflammations	0.178	0.822	0.000
H30.1 Disseminated chorioretinal inflammation	0.178	0.822	0.000
H30.0 Focal chorioretinal inflammation	0.178	0.822	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.000	0.828	0.172
O46.9 Antepartum haemorrhage, unspecified	0.000	0.829	0.171
H30.2 Posterior cyclitis	0.165	0.834	0.000
O34.3 Maternal care for cervical incompetence	0.000	0.843	0.157
O32 Maternal care for known or suspected malpresentation of foetus	0.000	0.843	0.157
O30.0 Twin pregnancy	0.000	0.845	0.155
O43.1 Malformation of placenta	0.000	0.854	0.145
H35.3 Degeneration of macula and posterior pole	0.144	0.856	0.000
H33 Retinal detachments and breaks	0.132	0.868	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.871	0.129
O43.9 Placental disorder, unspecified	0.001	0.871	0.128
O32.3 Maternal care for face, brow and chin presentation	0.000	0.879	0.120
O32.6 Maternal care for compound presentation	0.000	0.880	0.120
O32.9 Maternal care for malpresentation of foetus, unspecified	0.000	0.881	0.119
H33.4 Traction detachment of retina	0.119	0.881	0.000
O32.4 Maternal care for high head at term	0.000	0.881	0.118
O32.0 Maternal care for unstable lie	0.000	0.885	0.115
O42.9 Premature rupture of membranes, unspecified	0.000	0.886	0.114
O32.8 Maternal care for other malpresentation of foetus	0.000	0.893	0.106
O32.2 Maternal care for transverse and oblique lie	0.000	0.896	0.103
H33.0 Retinal detachment with retinal break	0.100	0.900	0.000
H33.1 Retinoschisis and retinal cysts	0.081	0.919	0.000
H35.8 Other specified retinal disorders	0.081	0.919	0.000
H33.5 Other retinal detachments	0.080	0.920	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.001	0.935	0.064
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.000	0.937	0.062
N48.6 Balanitis xerotica obliterans	0.050	0.950	0.000
H33.2 Serous retinal detachment	0.050	0.950	0.000
C71 Malignant neoplasm of brain	0.047	0.953	0.000
N48 Other disorders of penis	0.046	0.954	0.000
C71.9 Brain, unspecified	0.046	0.954	0.000
N48.4 Impotence of organic origin	0.045	0.955	0.000
N48.9 Disorder of penis, unspecified	0.044	0.956	0.000
C71.0 Cerebrum, except lobes and ventricles	0.043	0.957	0.000
C71.4 Occipital lobe	0.041	0.959	0.000
C71.1 Frontal lobe	0.040	0.960	0.000
N48.3 Priapism	0.039	0.961	0.000
N48.1 Balanoposthitis	0.039	0.961	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.039	0.961	0.000
C71.3 Parietal lobe	0.039	0.961	0.000
C69 Malignant neoplasm of eye and adnexa	0.039	0.961	0.000
C71.6 Cerebellum	0.037	0.963	0.000
C69.3 Choroid	0.037	0.963	0.000
C71.5 Cerebral ventricle	0.037	0.963	0.000
N48.0 Leukoplakia of penis	0.034	0.965	0.000
E11.3 With ophthalmic complications	0.033	0.967	0.000
C71.2 Temporal lobe	0.032	0.968	0.000
C69.9 Eye, unspecified	0.032	0.968	0.000
N48.5 Ulcer of penis	0.031	0.969	0.000
C71.7 Brain stem	0.031	0.969	0.000
C70 Malignant neoplasm of meninges	0.029	0.971	0.000
C69.6 Orbit	0.029	0.971	0.000
C69.4 Ciliary body	0.029	0.971	0.000
C69.0 Conjunctiva	0.029	0.971	0.000
C71.8 Overlapping lesion of brain	0.028	0.972	0.000
C69.8 Overlapping lesion of eye and adnexa	0.028	0.972	0.000
C69.5 Lachrymal gland and duct	0.028	0.972	0.000
C69.1 Cornea	0.028	0.972	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.027	0.972	0.000
O32.1 Maternal care for breech presentation	0.000	0.974	0.026
C78.2 Secondary malignant neoplasm of pleura	0.000	0.975	0.025
C69.2 Retina	0.024	0.976	0.000
E11 Non-insulin-dependent diabetes mellitus	0.024	0.976	0.000
N48.2 Other inflammatory disorders of penis	0.024	0.976	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.977	0.023
E11.2 With renal complications	0.023	0.977	0.000
C70.0 Cerebral meninges	0.022	0.978	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.000	0.978	0.022
C70.9 Meninges, unspecified	0.021	0.979	0.000
C70.1 Spinal meninges	0.021	0.979	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.980	0.020
C72.9 Central nervous system, unspecified	0.020	0.980	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.020	0.980	0.000
C72.5 Other and unspecified cranial nerves	0.020	0.980	0.000
C72.4 Acoustic nerve	0.020	0.980	0.000
C72.3 Optic nerve	0.020	0.980	0.000
C72.2 Olfactory nerve	0.020	0.980	0.000
C72.1 Cauda equina	0.020	0.980	0.000
O23 Infections of genito-urinary tract in pregnancy	0.000	0.980	0.020
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.980	0.020
E11.4 With neurological complications	0.019	0.981	0.000
C72.0 Spinal cord	0.019	0.981	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.981	0.019
E11.6 With other specified complications	0.019	0.981	0.000
E11.7 With multiple complications	0.018	0.981	0.000
E11.0 With coma	0.018	0.982	0.000
O22 Venous complications in pregnancy	0.000	0.983	0.017
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.983	0.017
E11.8 With unspecified complications	0.017	0.983	0.000
O28 Abnormal findings on antenatal screening of mother	0.000	0.983	0.016
O23.5 Infections of the genital tract in pregnancy	0.000	0.984	0.016
H33.3 Retinal breaks without detachment	0.016	0.984	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.984	0.016
O22.4 Haemorrhoids in pregnancy	0.000	0.984	0.016
E11.5 With peripheral circulatory complications	0.016	0.984	0.000
E11.1 With ketoacidosis	0.016	0.984	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.984	0.016
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.000	0.984	0.016
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.984	0.016
O29 Complications of anaesthesia during pregnancy	0.000	0.985	0.015
O25 Malnutrition in pregnancy	0.000	0.985	0.015
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.985	0.015
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.985	0.015
H81.0 Meniere's disease	0.015	0.985	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.000	0.985	0.014
O23.2 Infections of urethra in pregnancy	0.000	0.985	0.014
O23.1 Infections of bladder in pregnancy	0.000	0.985	0.014
O97 Death from sequelae of direct obstetric causes	0.000	0.986	0.014
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.000	0.986	0.014
O95 Obstetric death of unspecified cause	0.000	0.986	0.014
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.000	0.986	0.014
O21 Excessive vomiting in pregnancy	0.000	0.986	0.014
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.986	0.014
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.986	0.014
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.000	0.987	0.013
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.000	0.987	0.013
O22.3 Deep phlebothrombosis in pregnancy	0.000	0.987	0.013
O23.0 Infections of kidney in pregnancy	0.000	0.987	0.013
O26.0 Excessive weight gain in pregnancy	0.000	0.987	0.013
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.987	0.013
O22.9 Venous complication in pregnancy, unspecified	0.000	0.987	0.012
O22.8 Other venous complications in pregnancy	0.000	0.987	0.012
O22.5 Cerebral venous thrombosis in pregnancy	0.000	0.987	0.012
O22.2 Superficial thrombophlebitis in pregnancy	0.000	0.987	0.012
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.000	0.987	0.013
O21.0 Mild hyperemesis gravidarum	0.000	0.987	0.012
O26.5 Maternal hypotension syndrome	0.000	0.988	0.012
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O28.8 Other abnormal findings on antenatal screening of mother	0.000	0.988	0.012
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.000	0.988	0.012
O28.4 Abnormal radiological finding on antenatal screening of mother	0.000	0.988	0.012
O28.2 Abnormal cytological finding on antenatal screening of mother	0.000	0.988	0.012
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O26.2 Pregnancy care of habitual aborter	0.000	0.988	0.012
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O24 Diabetes mellitus in pregnancy	0.000	0.988	0.012
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O22.0 Varicose veins of lower extremity in pregnancy	0.000	0.988	0.011
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.000	0.989	0.011
O26.4 Herpes gestationis	0.000	0.989	0.011
O26.1 Low weight gain in pregnancy	0.000	0.989	0.011
O22.1 Genital varices in pregnancy	0.000	0.989	0.011
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.000	0.989	0.011
O03.4 Incomplete, without complication	0.000	0.989	0.011
O00-O08 Pregnancy with abortive outcome	0.000	0.989	0.011
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.000	0.989	0.011
O29.8 Other complications of anaesthesia during pregnancy	0.000	0.989	0.011
O29.6 Failed or difficult intubation during pregnancy	0.000	0.989	0.011
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.000	0.989	0.011
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.000	0.989	0.011
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.000	0.989	0.011
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.000	0.989	0.011
O29.1 Cardiac complications of anaesthesia during pregnancy	0.000	0.989	0.011
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.000	0.989	0.011
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.000	0.989	0.011
O28.0 Abnormal haematological finding on antenatal screening of mother	0.000	0.989	0.010
H81 Disorders of vestibular function	0.011	0.989	0.000
O96.9 Death from unspecified obstetric cause	0.000	0.989	0.010
O96.1 Death from indirect obstetric cause	0.000	0.989	0.010
O96.0 Death from direct obstetric cause	0.000	0.989	0.010
O97.9 Death from sequelae of obstetric cause, unspecified	0.000	0.989	0.010
O97.1 Death from sequelae of indirect obstetric cause	0.000	0.989	0.010
O97.0 Death from sequelae of direct obstetric cause	0.000	0.989	0.010
O26.8 Other specified pregnancy-related conditions	0.000	0.989	0.011
E11.9 Without complications	0.010	0.990	0.000
O03 Spontaneous abortion	0.000	0.990	0.010
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.000	0.990	0.010
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.990	0.010
O21.2 Late vomiting of pregnancy	0.000	0.990	0.010
H81.1 Benign paroxysmal vertigo	0.010	0.990	0.000
O21.9 Vomiting of pregnancy, unspecified	0.000	0.991	0.009
H81.9 Disorder of vestibular function, unspecified	0.009	0.991	0.000
H40.9 Glaucoma, unspecified	0.009	0.991	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.991	0.009
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.991	0.009
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.991	0.009
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.992	0.008
O21.8 Other vomiting complicating pregnancy	0.000	0.992	0.008
O06 Unspecified abortion	0.000	0.992	0.008
O05 Other abortion	0.000	0.992	0.008
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.992	0.008
O08 Complications following abortion and ectopic and molar pregnancy	0.000	0.992	0.008
O07 Failed attempted abortion	0.000	0.992	0.008
H81.2 Vestibular neuronitis	0.008	0.992	0.000
O20 Haemorrhage in early pregnancy	0.000	0.992	0.008
O01 Hydatidiform mole	0.000	0.992	0.008
K82.4 Cholesterolosis of gallbladder	0.008	0.992	0.000
O26.9 Pregnancy-related condition, unspecified	0.000	0.992	0.008
O03.7 Complete or unspecified, complicated by embolism	0.000	0.992	0.007
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.992	0.007
O03.2 Incomplete, complicated by embolism	0.000	0.992	0.007
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.992	0.007
H81.4 Vertigo of central origin	0.007	0.993	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.000	0.993	0.007
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.993	0.007
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.993	0.007
D13.2 Duodenum	0.007	0.993	0.000
H81.3 Other peripheral vertigo	0.007	0.993	0.000
H81.8 Other disorders of vestibular function	0.007	0.993	0.000
O20.8 Other haemorrhage in early pregnancy	0.000	0.993	0.007
O80-O84 Delivery	0.000	0.993	0.007
O03.3 Incomplete, with other and unspecified complications	0.000	0.993	0.006
N83.3 Acquired atrophy of ovary and Fallopian tube	0.000	0.993	0.007
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.006	0.994	0.000
O04 Medical abortion	0.000	0.994	0.006
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.994	0.006
O00 Ectopic pregnancy	0.000	0.994	0.006
H61.0 Perichondritis of external ear	0.006	0.994	0.000
O05.9 Complete or unspecified, without complication	0.000	0.994	0.006
O05.8 Complete or unspecified, with other and unspecified complications	0.000	0.994	0.006
O05.7 Complete or unspecified, complicated by embolism	0.000	0.994	0.006
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.994	0.006
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.994	0.006
O05.4 Incomplete, without complication	0.000	0.994	0.006
O05.3 Incomplete, with other and unspecified complications	0.000	0.994	0.006
O05.2 Incomplete, complicated by embolism	0.000	0.994	0.006
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.994	0.006
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.994	0.006
O06.9 Complete or unspecified, without complication	0.000	0.994	0.006
O06.8 Complete or unspecified, with other and unspecified complications	0.000	0.994	0.006
O06.7 Complete or unspecified, complicated by embolism	0.000	0.994	0.006
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.994	0.006
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.994	0.006
O06.4 Incomplete, without complication	0.000	0.994	0.006
O06.3 Incomplete, with other and unspecified complications	0.000	0.994	0.006
O06.2 Incomplete, complicated by embolism	0.000	0.994	0.006
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.994	0.006
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.994	0.006
O15 Eclampsia	0.000	0.994	0.006
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.994	0.006
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.000	0.994	0.006
O01.9 Hydatidiform mole, unspecified	0.000	0.994	0.006
H40.1 Primary open-angle glaucoma	0.006	0.994	0.000
O07.9 Other and unspecified failed attempted abortion, without complication	0.000	0.994	0.006
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.000	0.994	0.006
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.000	0.994	0.006
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.000	0.994	0.006
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.000	0.994	0.006
O07.3 Failed medical abortion, with other and unspecified complications	0.000	0.994	0.006
O07.2 Failed medical abortion, complicated by embolism	0.000	0.994	0.006
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.000	0.994	0.006
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.000	0.994	0.006
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.000	0.994	0.006
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.000	0.994	0.006
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.000	0.994	0.006
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.000	0.994	0.006
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.000	0.994	0.006
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.000	0.994	0.006
O08.3 Shock following abortion and ectopic and molar pregnancy	0.000	0.994	0.006
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.000	0.994	0.006
H40.2 Primary angle-closure glaucoma	0.006	0.994	0.000
H61 Other disorders of external ear	0.006	0.994	0.000
T14.0 Superficial injury of unspecified body region	0.000	0.994	0.006
N48.8 Other specified disorders of penis	0.006	0.994	0.000
H40 Glaucoma	0.006	0.994	0.000
O01.1 Incomplete and partial hydatidiform mole	0.000	0.994	0.006
O07.4 Failed medical abortion, without complication	0.000	0.994	0.006
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.994	0.006
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.000	0.994	0.006
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.994	0.006
H80-H83 Diseases of inner ear	0.005	0.995	0.000
O01.0 Classical hydatidiform mole	0.000	0.995	0.005
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.995	0.005
O84 Multiple delivery	0.000	0.995	0.005
H60-H62 Diseases of external ear	0.005	0.995	0.000
O14.1 Severe preeclampsia	0.000	0.995	0.005
H61.8 Other specified disorders of external ear	0.005	0.995	0.000
H61.2 Impacted cerumen	0.005	0.995	0.000
O14.0 Moderate preeclampsia	0.000	0.995	0.005
H61.9 Disorder of external ear, unspecified	0.005	0.995	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
O83 Other assisted single delivery	0.000	0.995	0.005
O85-O92 Complications predominantly related to the puerperium	0.000	0.995	0.005
O00.9 Ectopic pregnancy, unspecified	0.000	0.995	0.005
O04.7 Complete or unspecified, complicated by embolism	0.000	0.995	0.005
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.995	0.005
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.995	0.005
O04.3 Incomplete, with other and unspecified complications	0.000	0.995	0.005
O04.2 Incomplete, complicated by embolism	0.000	0.995	0.005
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.995	0.005
O14.2 HELLP syndrome	0.000	0.995	0.005
H40.8 Other glaucoma	0.005	0.995	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.000	0.995	0.005
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.995	0.005
O00.8 Other ectopic pregnancy	0.000	0.995	0.005
O00.2 Ovarian pregnancy	0.000	0.995	0.005
O00.0 Abdominal pregnancy	0.000	0.995	0.005
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.004
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.004
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.004
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.004
H60.9 Otitis externa, unspecified	0.005	0.995	0.000
O15.9 Eclampsia, unspecified as to time period	0.000	0.995	0.004
O15.2 Eclampsia in the puerperium	0.000	0.995	0.004
O15.1 Eclampsia in labour	0.000	0.995	0.004
O15.0 Eclampsia in pregnancy	0.000	0.995	0.004
O12.1 Gestational proteinuria	0.000	0.995	0.005
O12.0 Gestational oedema	0.000	0.995	0.005
H40.6 Glaucoma secondary to drugs	0.004	0.995	0.000
H60 Otitis externa	0.005	0.995	0.000
H61.3 Acquired stenosis of external ear canal	0.004	0.995	0.000
K82 Other diseases of gallbladder	0.005	0.995	0.000
J93.9 Pneumothorax, unspecified	0.000	0.995	0.005
H62 Disorders of external ear in diseases classified elsewhere	0.004	0.996	0.000
O81 Single delivery by forceps and vacuum extractor	0.000	0.996	0.004
O04.4 Incomplete, without complication	0.000	0.996	0.004
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O02 Other abnormal products of conception	0.000	0.996	0.004
K82.9 Disease of gallbladder, unspecified	0.004	0.996	0.000
O14.9 Preeclampsia, unspecified	0.000	0.996	0.004
H82 Vertiginous syndromes in diseases classified elsewhere	0.004	0.996	0.000
H40.4 Glaucoma secondary to eye inflammation	0.004	0.996	0.000
O84.2 Multiple delivery, all by Caesarean section	0.000	0.996	0.004
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
H80 Otosclerosis	0.004	0.996	0.000
H40.3 Glaucoma secondary to eye trauma	0.004	0.996	0.000
H61.1 Non-infective disorders of pinna	0.004	0.996	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.996	0.004
H10.9 Conjunctivitis, unspecified	0.000	0.996	0.004
O84.9 Multiple delivery, unspecified	0.000	0.996	0.004
O84.8 Other multiple delivery	0.000	0.996	0.004
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.000	0.996	0.004
O84.0 Multiple delivery, all spontaneous	0.000	0.996	0.004
H60.3 Other infective otitis externa	0.004	0.996	0.000
O12.2 Gestational oedema with proteinuria	0.000	0.996	0.004
O16 Unspecified maternal hypertension	0.000	0.996	0.004
K82.3 Fistula of gallbladder	0.004	0.996	0.000
H60.1 Cellulitis of external ear	0.004	0.996	0.000
K82.1 Hydrops of gallbladder	0.004	0.996	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.004	0.996	0.000
I78.1 Naevus, nonneoplastic	0.004	0.996	0.000
M25.50 Pain in joint (Multiple sites)	0.000	0.996	0.004
O87 Venous complications in the puerperium	0.000	0.996	0.004
O91 Infections of breast associated with childbirth	0.000	0.996	0.004
O83.9 Assisted single delivery, unspecified	0.000	0.996	0.004
O83.8 Other specified assisted single delivery	0.000	0.996	0.004
O83.4 Destructive operation for delivery	0.000	0.996	0.004
O83.3 Delivery of viable foetus in abdominal pregnancy	0.000	0.996	0.004
O83.2 Other manipulation-assisted delivery	0.000	0.996	0.004
O83.0 Breech extraction	0.000	0.996	0.004
O88 Obstetric embolism	0.000	0.996	0.003
K82.0 Obstruction of gallbladder	0.004	0.996	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.000	0.996	0.004
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.996	0.004
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.996	0.004
L29.9 Pruritus, unspecified	0.004	0.996	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.004	0.996	0.000
O20.0 Threatened abortion	0.000	0.996	0.004
O83.1 Other assisted breech delivery	0.000	0.996	0.003
K82.2 Perforation of gallbladder	0.003	0.996	0.000
Chapter VIII Diseases of the ear and mastoid process	0.004	0.996	0.000
O89 Complications of anaesthesia during the puerperium	0.000	0.996	0.003
H62.8 Other disorders of external ear in diseases classified elsewhere	0.003	0.997	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.003	0.997	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H62.2 Otitis externa in mycoses	0.003	0.997	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.003	0.997	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.000	0.997	0.003
O81.2 Mid-cavity forceps with rotation	0.000	0.997	0.003
O81.1 Mid-cavity forceps delivery	0.000	0.997	0.003
H20.0 Acute and subacute iridocyclitis	0.000	0.997	0.003
O02.9 Abnormal product of conception, unspecified	0.000	0.997	0.003
O04.9 Complete or unspecified, without complication	0.000	0.997	0.003
H60.5 Acute otitis externa, non-infective	0.003	0.997	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.003	0.997	0.000
O81.4 Vacuum extractor delivery	0.000	0.997	0.003
O87.8 Other venous complications in the puerperium	0.000	0.997	0.003
O02.8 Other specified abnormal products of conception	0.000	0.997	0.003
D03.5 Melanoma in situ of trunk	0.003	0.997	0.000
O81.0 Low forceps delivery	0.000	0.997	0.003
H80.8 Other otosclerosis	0.003	0.997	0.000
H80.2 Cochlear otosclerosis	0.003	0.997	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.003	0.997	0.000
H60.0 Abscess of external ear	0.003	0.997	0.000
O81.3 Other and unspecified forceps delivery	0.000	0.997	0.003
H60.2 Malignant otitis externa	0.003	0.997	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations