TreeWAS – Variant ID: rs4938933

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H54.7 Unspecified visual loss	0.071	0.929	0.000
H54.0 Blindness, both eyes	0.055	0.945	0.000
H54 Blindness and low vision	0.053	0.947	0.000
H54.1 Blindness, one eye, low vision, other eye	0.044	0.956	0.000
H54.3 Unqualified visual loss, both eyes	0.040	0.959	0.000
H54.2 Low vision, both eyes	0.039	0.961	0.000
H54.5 Low vision, one eye	0.033	0.967	0.000
H54.9 Unspecified visual impairment (binocular)	0.029	0.971	0.000
K60.1 Chronic anal fissure	0.000	0.972	0.028
E53.8 Deficiency of other specified B group vitamins	0.000	0.973	0.027
H54.6 Unqualified visual loss, one eye	0.025	0.974	0.000
E53 Deficiency of other B group vitamins	0.000	0.982	0.018
E53.9 Vitamin B deficiency, unspecified	0.000	0.985	0.015
R09.0 Asphyxia	0.013	0.987	0.000
E53.1 Pyridoxine deficiency	0.000	0.987	0.013
E53.0 Riboflavin deficiency	0.000	0.987	0.013
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.987	0.013
R09.1 Pleurisy	0.013	0.987	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.000	0.988	0.012
G30 Alzheimer's disease	0.012	0.988	0.000
T88.4 Failed or difficult intubation	0.000	0.988	0.012
G30.0 Alzheimer's disease with early onset	0.012	0.988	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.012	0.988	0.000
G30.9 Alzheimer's disease, unspecified	0.011	0.989	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.000	0.989	0.011
T88.5 Other complications of anaesthesia	0.000	0.989	0.011
G30.8 Other Alzheimer's disease	0.011	0.989	0.000
T88.2 Shock due to anaesthesia	0.000	0.990	0.010
G30.1 Alzheimer's disease with late onset	0.010	0.990	0.000
I84.5 External haemorrhoids without complication	0.010	0.990	0.000
H54.4 Blindness, one eye	0.010	0.990	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.000	0.990	0.010
T88.9 Complication of surgical and medical care, unspecified	0.000	0.991	0.009
T88.1 Other complications following immunisation, not elsewhere classified	0.000	0.991	0.009
T88.0 Infection following immunisation	0.000	0.991	0.009
N28.1 Cyst of kidney, acquired	0.009	0.991	0.000
H53-H54 Visual disturbances and blindness	0.009	0.991	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.009	0.991	0.000
R09.3 Abnormal sputum	0.009	0.991	0.000
G30-G32 Other degenerative diseases of the nervous system	0.008	0.992	0.000
M95.0 Acquired deformity of nose	0.000	0.992	0.008
G31.0 Circumscribed brain atrophy	0.008	0.992	0.000
R09.2 Respiratory arrest	0.008	0.992	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.000	0.992	0.008
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.008	0.992	0.000
E50-E64 Other nutritional deficiencies	0.000	0.992	0.008
S12.20 Fracture of other specified cervical vertebra (closed)	0.007	0.993	0.000
G31.2 Degeneration of nervous system due to alcohol	0.007	0.993	0.000
N13.4 Hydroureter	0.007	0.993	0.000
E55 Vitamin D deficiency	0.000	0.993	0.007
N13.3 Other and unspecified hydronephrosis	0.007	0.993	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.006	0.993	0.000
G31.8 Other specified degenerative diseases of nervous system	0.006	0.993	0.000
N13 Obstructive and reflux uropathy	0.006	0.994	0.000
N99.0 Postprocedural renal failure	0.006	0.994	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.994	0.006
G31.1 Senile degeneration of brain, not elsewhere classified	0.006	0.994	0.000
N13.8 Other obstructive and reflux uropathy	0.006	0.994	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.006	0.994	0.000
E58 Dietary calcium deficiency	0.000	0.994	0.006
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.994	0.006
E50 Vitamin A deficiency	0.000	0.994	0.006
E60 Dietary zinc deficiency	0.000	0.994	0.006
E59 Dietary selenium deficiency	0.000	0.994	0.006
E52 Niacin deficiency [pellagra]	0.000	0.994	0.006
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.000	0.994	0.006
N13.5 Kinking and stricture of ureter without hydronephrosis	0.006	0.994	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.994	0.006
E63 Other nutritional deficiencies	0.000	0.994	0.005
E56 Other vitamin deficiencies	0.000	0.994	0.005
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.006	0.994	0.000
E51 Thiamine deficiency	0.000	0.994	0.005
E54 Ascorbic acid deficiency	0.000	0.995	0.005
E61 Deficiency of other nutrient elements	0.000	0.995	0.005
N99.1 Postprocedural urethral stricture	0.005	0.995	0.000
N64.8 Other specified disorders of breast	0.000	0.995	0.005
N99.4 Postprocedural pelvic peritoneal adhesions	0.005	0.995	0.000
D11.0 Parotid gland	0.005	0.995	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.005	0.995	0.000
E55.0 Rickets, active	0.000	0.995	0.005
N99.5 Malfunction of external stoma of urinary tract	0.005	0.995	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.005	0.995	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.005	0.995	0.000
M95.3 Acquired deformity of neck	0.000	0.995	0.005
M95.2 Other acquired deformity of head	0.000	0.995	0.005
E61.2 Magnesium deficiency	0.000	0.996	0.004
S12.2 Fracture of other specified cervical vertebra	0.004	0.996	0.000
E50.9 Vitamin A deficiency, unspecified	0.000	0.996	0.004
E50.8 Other manifestations of vitamin A deficiency	0.000	0.996	0.004
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.996	0.004
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.996	0.004
E50.5 Vitamin A deficiency with night blindness	0.000	0.996	0.004
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.996	0.004
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.996	0.004
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.996	0.004
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.996	0.004
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.996	0.004
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.996	0.004
E64.8 Sequelae of other nutritional deficiencies	0.000	0.996	0.004
E64.3 Sequelae of rickets	0.000	0.996	0.004
E64.2 Sequelae of vitamin C deficiency	0.000	0.996	0.004
E64.1 Sequelae of vitamin A deficiency	0.000	0.996	0.004
E64.0 Sequelae of protein-energy malnutrition	0.000	0.996	0.004
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.000	0.996	0.004
M95.8 Other specified acquired deformities of musculoskeletal system	0.000	0.996	0.004
M95.5 Acquired deformity of pelvis	0.000	0.996	0.004
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.004	0.996	0.000
J18.0 Bronchopneumonia, unspecified	0.000	0.996	0.004
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.004	0.996	0.000
E63.8 Other specified nutritional deficiencies	0.000	0.996	0.004
E63.1 Imbalance of constituents of food intake	0.000	0.996	0.004
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.996	0.004
M95.4 Acquired deformity of chest and rib	0.000	0.996	0.004
E56.9 Vitamin deficiency, unspecified	0.000	0.996	0.004
E56.8 Deficiency of other vitamins	0.000	0.996	0.004
E56.0 Deficiency of vitamin E	0.000	0.996	0.004
M95.1 Cauliflower ear	0.000	0.996	0.004
E51.9 Thiamine deficiency, unspecified	0.000	0.996	0.004
E51.8 Other manifestations of thiamine deficiency	0.000	0.996	0.004
E51.1 Beriberi	0.000	0.996	0.004
S22.20 Fracture of sternum (closed)	0.000	0.996	0.004
G24.9 Dystonia, unspecified	0.000	0.996	0.004
E63.9 Nutritional deficiency, unspecified	0.000	0.996	0.004
E61.9 Deficiency of nutrient element, unspecified	0.000	0.996	0.004
E61.8 Deficiency of other specified nutrient elements	0.000	0.996	0.004
E61.7 Deficiency of multiple nutrient elements	0.000	0.996	0.004
E61.6 Vanadium deficiency	0.000	0.996	0.004
E61.5 Molybdenum deficiency	0.000	0.996	0.004
E61.4 Chromium deficiency	0.000	0.996	0.004
E61.3 Manganese deficiency	0.000	0.996	0.004
E61.0 Copper deficiency	0.000	0.996	0.004
E56.1 Deficiency of vitamin K	0.000	0.996	0.004
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.004	0.996	0.000
C67.9 Bladder, unspecified	0.004	0.996	0.000
E51.2 Wernicke's encephalopathy	0.000	0.996	0.004
N99.8 Other postprocedural disorders of genito-urinary system	0.004	0.996	0.000
H11 Other disorders of conjunctiva	0.000	0.996	0.004
N99.2 Postprocedural adhesions of vagina	0.004	0.996	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.004	0.996	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.000	0.996	0.004
H11.3 Conjunctival haemorrhage	0.000	0.996	0.004
N13.9 Obstructive and reflux uropathy, unspecified	0.004	0.996	0.000
G24 Dystonia	0.000	0.996	0.004
N13.6 Pyonephrosis	0.003	0.996	0.000
D11 Benign neoplasm of major salivary glands	0.004	0.996	0.000
H11.1 Conjunctival degenerations and deposits	0.000	0.996	0.003
S12.21 Fracture of other specified cervical vertebra (open)	0.003	0.997	0.000
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.000	0.997	0.003
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.997	0.003
M50.1 Cervical disk disorder with radiculopathy	0.000	0.997	0.003
S92.30 Fracture of metatarsal bone (closed)	0.003	0.997	0.000
D11.9 Major salivary gland, unspecified	0.003	0.997	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.000	0.997	0.003
G24.8 Other dystonia	0.000	0.997	0.003
G24.1 Idiopathic familial dystonia	0.000	0.997	0.003
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.000	0.997	0.003
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.000	0.997	0.003
G24.5 Blepharospasm	0.000	0.997	0.003
D11.7 Other major salivary glands	0.003	0.997	0.000
G24.3 Spasmodic torticollis	0.000	0.997	0.003
E61.1 Iron deficiency	0.000	0.997	0.003
C15.5 Lower third of oesophagus	0.003	0.997	0.000
S82.00 Fracture of patella (closed)	0.000	0.997	0.003
G24.0 Drug-induced dystonia	0.000	0.997	0.003
G24.4 Idiopathic orofacial dystonia	0.000	0.997	0.003
G24.2 Idiopathic nonfamilial dystonia	0.000	0.997	0.003
H11.2 Conjunctival scars	0.000	0.997	0.003
H11.8 Other specified disorders of conjunctiva	0.000	0.997	0.003
M50.3 Other cervical disk degeneration	0.000	0.997	0.003
C25.0 Head of pancreas	0.000	0.997	0.003
E14.3 With ophthalmic complications	0.003	0.997	0.000
F10.4 Withdrawal state with delirium	0.000	0.997	0.003
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.000	0.997	0.003
M50 Cervical disk disorders	0.000	0.997	0.003
N05.9 Unspecified	0.000	0.997	0.003
K10.8 Other specified diseases of jaws	0.003	0.997	0.000
S92.3 Fracture of metatarsal bone	0.003	0.997	0.000
H11.9 Disorder of conjunctiva, unspecified	0.000	0.997	0.003
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.000	0.997	0.002
M96.5 Postradiation scoliosis	0.000	0.997	0.002
M96.4 Postsurgical lordosis	0.000	0.997	0.002
M96.3 Postlaminectomy kyphosis	0.000	0.997	0.002
M96.2 Postradiation kyphosis	0.000	0.997	0.002
S12.00 Fracture of first cervical vertebra (closed)	0.002	0.997	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.997	0.002
H11.0 Pterygium	0.000	0.998	0.002
S12.0 Fracture of first cervical vertebra	0.002	0.998	0.000
S12 Fracture of neck	0.002	0.998	0.000
M50.8 Other cervical disk disorders	0.000	0.998	0.002
M96.8 Other postprocedural musculoskeletal disorders	0.000	0.998	0.002
M50.9 Cervical disk disorder, unspecified	0.000	0.998	0.002
N99-N99 Other disorders of the genitourinary system	0.002	0.998	0.000
M25.54 Pain in joint (Hand)	0.000	0.998	0.002
G25.0 Essential tremor	0.000	0.998	0.002
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.000	0.998	0.002
S92.70 Multiple fractures of foot (closed)	0.002	0.998	0.000
B02.2 Zoster with other nervous system involvement	0.000	0.998	0.002
N05.2 Diffuse membranous glomerulonephritis	0.000	0.998	0.002
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.998	0.002
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
M50.0 Cervical disk disorder with myelopathy	0.000	0.998	0.002
N99.3 Prolapse of vaginal vault after hysterectomy	0.002	0.998	0.000
R23.1 Pallor	0.002	0.998	0.000
M99 Biomechanical lesions, not elsewhere classified	0.000	0.998	0.002
G71.1 Myotonic disorders	0.002	0.998	0.000
Q18 Other congenital malformations of face and neck	0.002	0.998	0.000
N05.1 Focal and segmental glomerular lesions	0.000	0.998	0.002
S92.7 Multiple fractures of foot	0.002	0.998	0.000
N05 Unspecified nephritic syndrome	0.000	0.998	0.002
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
D35.0 Adrenal gland	0.002	0.998	0.000
H10.9 Conjunctivitis, unspecified	0.000	0.998	0.002
I77.1 Stricture of artery	0.000	0.998	0.002
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.000	0.998	0.002
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.000	0.998	0.002
S92.4 Fracture of great toe	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
H10-H13 Disorders of conjunctiva	0.000	0.998	0.002
S12.01 Fracture of first cervical vertebra (open)	0.002	0.998	0.000
S12.8 Fracture of other parts of neck	0.002	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
S12.7 Multiple fractures of cervical spine	0.002	0.998	0.000
S22.2 Fracture of sternum	0.000	0.998	0.002
T78.1 Other adverse food reactions, not elsewhere classified	0.002	0.998	0.000
H10 Conjunctivitis	0.000	0.998	0.002
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.998	0.002
H02.4 Ptosis of eyelid	0.000	0.998	0.002
M50.2 Other cervical disk displacement	0.000	0.998	0.002
M99.9 Biomechanical lesion, unspecified	0.000	0.998	0.002
M99.6 Osseous and subluxation stenosis of intervertebral foramina	0.000	0.998	0.002
M99.4 Connective tissue stenosis of neural canal	0.000	0.998	0.002
M99.3 Osseous stenosis of neural canal	0.000	0.998	0.002
M99.2 Subluxation stenosis of neural canal	0.000	0.998	0.002
M99.1 Subluxation complex (vertebral)	0.000	0.998	0.002
M99.0 Segmental and somatic dysfunction	0.000	0.998	0.002
S92.1 Fracture of talus	0.002	0.998	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.002	0.998	0.000
M99.8 Other biomechanical lesions	0.000	0.998	0.002
Q18.9 Congenital malformation of face and neck, unspecified	0.002	0.998	0.000
Q18.8 Other specified congenital malformations of face and neck	0.002	0.998	0.000
Q18.7 Microcheilia	0.002	0.998	0.000
Q18.6 Macrocheilia	0.002	0.998	0.000
Q18.5 Microstomia	0.002	0.998	0.000
Q18.4 Macrostomia	0.002	0.998	0.000
Q18.3 Webbing of neck	0.002	0.998	0.000
Q18.2 Other branchial cleft malformations	0.002	0.998	0.000
W17.4 Street and highway	0.002	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.002	0.998	0.000
N05.6 Dense deposit disease	0.000	0.998	0.002
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.998	0.002
N05.0 Minor glomerular abnormality	0.000	0.998	0.002
G31.9 Degenerative disease of nervous system, unspecified	0.002	0.998	0.000
S82.0 Fracture of patella	0.000	0.998	0.002
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.998	0.002
G12.2 Motor neuron disease	0.002	0.998	0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina	0.000	0.998	0.002
N05.8 Other	0.000	0.998	0.002
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.998	0.002
N05.7 Diffuse crescentic glomerulonephritis	0.000	0.998	0.002
S12.9 Fracture of neck, part unspecified	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.002	0.998	0.000
N80.9 Endometriosis, unspecified	0.000	0.998	0.002
N39.9 Disorder of urinary system, unspecified	0.002	0.998	0.000
S12.1 Fracture of second cervical vertebra	0.002	0.998	0.000
S92.5 Fracture of other toe	0.002	0.998	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.000	0.998	0.002
Y88 Sequelae of surgical and medical care as external cause	0.002	0.998	0.000
S12.81 Fracture of other parts of neck (open)	0.001	0.998	0.000
S12.80 Fracture of other parts of neck (closed)	0.001	0.998	0.000
H10.5 Blepharoconjunctivitis	0.000	0.998	0.002
H10.0 Mucopurulent conjunctivitis	0.000	0.998	0.002
S92.11 Fracture of talus (open)	0.002	0.998	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.002	0.998	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.998	0.002
M31.3 Wegener's granulomatosis	0.000	0.998	0.002
M99.5 Intervertebral disk stenosis of neural canal	0.000	0.998	0.001
S12.71 Multiple fractures of cervical spine (open)	0.001	0.998	0.000
S22.21 Fracture of sternum (open)	0.000	0.998	0.001
N88.2 Stricture and stenosis of cervix uteri	0.000	0.998	0.002
Q18.1 Preauricular sinus and cyst	0.002	0.998	0.000
G71 Primary disorders of muscles	0.002	0.998	0.000
H10.2 Other acute conjunctivitis	0.000	0.998	0.001
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
M99.09 Segmental and somatic dysfunction (Abdomen and other)	0.000	0.998	0.001
M99.08 Segmental and somatic dysfunction (Rib cage)	0.000	0.998	0.001
M99.07 Segmental and somatic dysfunction (Upper extremity)	0.000	0.998	0.001
M99.06 Segmental and somatic dysfunction (Lower extremity)	0.000	0.998	0.001
M99.05 Segmental and somatic dysfunction (Pelvic region)	0.000	0.998	0.001
M99.04 Segmental and somatic dysfunction (Sacral region)	0.000	0.998	0.001
M99.03 Segmental and somatic dysfunction (Lumbar region)	0.000	0.998	0.001
M99.02 Segmental and somatic dysfunction (Thoracic region)	0.000	0.998	0.001
M99.01 Segmental and somatic dysfunction (Cervical region)	0.000	0.998	0.001
M99.00 Segmental and somatic dysfunction (Head region)	0.000	0.998	0.001
M99.19 Subluxation complex (vertebral) (Abdomen and other)	0.000	0.998	0.001
M99.18 Subluxation complex (vertebral) (Rib cage)	0.000	0.998	0.001
M99.17 Subluxation complex (vertebral) (Upper extremity)	0.000	0.998	0.001
M99.16 Subluxation complex (vertebral) (Lower extremity)	0.000	0.998	0.001
M99.15 Subluxation complex (vertebral) (Pelvic region)	0.000	0.998	0.001
M99.14 Subluxation complex (vertebral) (Sacral region)	0.000	0.998	0.001
M99.13 Subluxation complex (vertebral) (Lumbar region)	0.000	0.998	0.001
M99.12 Subluxation complex (vertebral) (Thoracic region)	0.000	0.998	0.001
M99.11 Subluxation complex (vertebral) (Cervical region)	0.000	0.998	0.001
M99.10 Subluxation complex (vertebral) (Head region)	0.000	0.998	0.001
M99.29 Subluxation stenosis of neural canal-Abdomen/other	0.000	0.998	0.001
M99.28 Subluxation stenosis of neural canal-Rib cage	0.000	0.998	0.001
M99.27 Subluxation stenosis of neural canal-Upper extremity	0.000	0.998	0.001
M99.26 Subluxation stenosis of neural canal-Lower extremity	0.000	0.998	0.001
M99.25 Subluxation stenosis of neural canal (Pelvic region)	0.000	0.998	0.001
M99.24 Subluxation stenosis of neural canal (Sacral region)	0.000	0.998	0.001
M99.23 Subluxation stenosis of neural canal (Lumbar region)	0.000	0.998	0.001
M99.22 Subluxation stenosis of neural canal (Thoracic region)	0.000	0.998	0.001
M99.21 Subluxation stenosis of neural canal (Cervical region)	0.000	0.998	0.001
M99.20 Subluxation stenosis of neural canal (Head region)	0.000	0.998	0.001
M99.39 Osseous stenosis of neural canal-Abdomen/other	0.000	0.998	0.001
M99.38 Osseous stenosis of neural canal-Rib cage	0.000	0.998	0.001
M99.37 Osseous stenosis of neural canal-Upper extremity	0.000	0.998	0.001
M99.36 Osseous stenosis of neural canal-Lower extremity	0.000	0.998	0.001
M99.35 Osseous stenosis of neural canal (Pelvic region)	0.000	0.998	0.001
M99.34 Osseous stenosis of neural canal (Sacral region)	0.000	0.998	0.001
M99.33 Osseous stenosis of neural canal (Lumbar region)	0.000	0.998	0.001
M99.32 Osseous stenosis of neural canal (Thoracic region)	0.000	0.998	0.001
M99.31 Osseous stenosis of neural canal (Cervical region)	0.000	0.998	0.001
M99.30 Osseous stenosis of neural canal (Head region)	0.000	0.998	0.001
M99.49 Connective tissue stenosis of neural canal-Abdomen/other	0.000	0.998	0.001
M99.48 Connective tissue stenosis of neural canal-Rib cage	0.000	0.998	0.001
M99.47 Connective tissue stenosis of neural canal-Upper extremity	0.000	0.998	0.001
M99.46 Connective tissue stenosis of neural canal-Lower extremity	0.000	0.998	0.001
M99.45 Connective tissue stenosis of neural canal (Pelvic region)	0.000	0.998	0.001
M99.44 Connective tissue stenosis of neural canal (Sacral region)	0.000	0.998	0.001
M99.43 Connective tissue stenosis of neural canal (Lumbar region)	0.000	0.998	0.001
M99.42 Connective tissue stenosis of neural canal (Thoracic region)	0.000	0.998	0.001
M99.41 Connective tissue stenosis of neural canal (Cervical region)	0.000	0.998	0.001
M99.40 Connective tissue stenosis of neural canal (Head region)	0.000	0.998	0.001
M99.69 Osseous and subluxation stenosis of intervertebral foramina	0.000	0.998	0.001
M99.68 Osseous and subluxation stenosis of intervertebral foramina	0.000	0.998	0.001
M99.67 Osseous and subluxation stenosis of intervertebral foramina	0.000	0.998	0.001
M99.66 Osseous and subluxation stenosis of intervertebral foramina	0.000	0.998	0.001
M99.65 Osseous and subluxation stenosis of intervertebral foramina (Pelvic region)	0.000	0.998	0.001
M99.64 Osseous and subluxation stenosis of intervertebral foramina (Sacral region)	0.000	0.998	0.001
M99.63 Osseous and subluxation stenosis of intervertebral foramina (Lumbar region)	0.000	0.998	0.001
M99.62 Osseous and subluxation stenosis of intervertebral foramina (Thoracic region)	0.000	0.998	0.001
M99.61 Osseous and subluxation stenosis of intervertebral foramina (Cervical region)	0.000	0.998	0.001
M99.60 Osseous and subluxation stenosis of intervertebral foramina (Head region)	0.000	0.998	0.001
M99.99 Biomechanical lesion, unspecified (Abdomen and other)	0.000	0.998	0.001
M99.98 Biomechanical lesion, unspecified (Rib cage)	0.000	0.998	0.001
M99.97 Biomechanical lesion, unspecified (Upper extremity)	0.000	0.998	0.001
M99.96 Biomechanical lesion, unspecified (Lower extremity)	0.000	0.998	0.001
M99.95 Biomechanical lesion, unspecified (Pelvic region)	0.000	0.998	0.001
M99.94 Biomechanical lesion, unspecified (Sacral region)	0.000	0.998	0.001
M99.93 Biomechanical lesion, unspecified (Lumbar region)	0.000	0.998	0.001
M99.92 Biomechanical lesion, unspecified (Thoracic region)	0.000	0.998	0.001
M99.91 Biomechanical lesion, unspecified (Cervical region)	0.000	0.998	0.001
M99.90 Biomechanical lesion, unspecified (Head region)	0.000	0.998	0.001
S92.41 Fracture of great toe (open)	0.001	0.998	0.000
H10.8 Other conjunctivitis	0.000	0.998	0.001
S92.10 Fracture of talus (closed)	0.002	0.998	0.000
R57.0 Cardiogenic shock	0.002	0.998	0.000
S82.8 Fractures of other parts of lower leg	0.000	0.998	0.002
M99.89 Other biomechanical lesions (Abdomen and other)	0.000	0.998	0.001
M99.88 Other biomechanical lesions (Rib cage)	0.000	0.998	0.001
M99.87 Other biomechanical lesions (Upper extremity)	0.000	0.998	0.001
M99.86 Other biomechanical lesions (Lower extremity)	0.000	0.998	0.001
M99.85 Other biomechanical lesions (Pelvic region)	0.000	0.998	0.001
M99.84 Other biomechanical lesions (Sacral region)	0.000	0.998	0.001
M99.82 Other biomechanical lesions (Thoracic region)	0.000	0.998	0.001
M99.80 Other biomechanical lesions (Head region)	0.000	0.998	0.001
S82.81 Fractures of other parts of lower leg (open)	0.000	0.998	0.002
E89.0 Postprocedural hypothyroidism	0.000	0.998	0.002
M99.81 Other biomechanical lesions (Cervical region)	0.000	0.998	0.001
S92.51 Fracture of other toe (open)	0.001	0.998	0.000
C25.9 Pancreas, unspecified	0.000	0.998	0.002
M99.79 Connective tis and disc stenosis of intervertebral foramina	0.000	0.998	0.001
M99.78 Connective tis and disc stenosis of intervertebral foramina	0.000	0.998	0.001
M99.77 Connective tis and disc stenosis of intervertebral foramina	0.000	0.998	0.001
M99.76 Connective tis and disc stenosis of intervertebral foramina	0.000	0.998	0.001
M99.75 Connective tissue and disc stenosis of intervertebral foramina (Pelvic region)	0.000	0.998	0.001
M99.74 Connective tissue and disc stenosis of intervertebral foramina (Sacral region)	0.000	0.998	0.001
M99.73 Connective tissue and disc stenosis of intervertebral foramina (Lumbar region)	0.000	0.998	0.001
M99.72 Connective tissue and disc stenosis of intervertebral foramina (Thoracic region)	0.000	0.998	0.001
M99.70 Connective tissue and disc stenosis of intervertebral foramina (Head region)	0.000	0.998	0.001
M99.83 Other biomechanical lesions (Lumbar region)	0.000	0.998	0.001
H10.4 Chronic conjunctivitis	0.000	0.998	0.001
N75.1 Abscess of Bartholin's gland	0.000	0.998	0.002
R26.0 Ataxic gait	0.000	0.998	0.002
S12.91 Fracture of neck, part unspecified (open)	0.001	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.001	0.998	0.000
D09.0 Bladder	0.002	0.998	0.000
E06.3 Autoimmune thyroiditis	0.002	0.998	0.000
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.001	0.998	0.000
S12.11 Fracture of second cervical vertebra (open)	0.001	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.001	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.001	0.998	0.000
G93.8 Other specified disorders of brain	0.002	0.998	0.000
W17.3 Sports and athletics area	0.002	0.998	0.000
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use	0.001	0.998	0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.000	0.998	0.001
H13.2 Conjunctivitis in other diseases classified elsewhere	0.000	0.998	0.001
H13.0 Filarial infection of conjunctiva	0.000	0.998	0.001
C25 Malignant neoplasm of pancreas	0.000	0.998	0.002
S82.51 Fracture of medial malleolus (open)	0.000	0.998	0.001
M99.71 Connective tissue and disc stenosis of intervertebral foramina (Cervical region)	0.000	0.998	0.001
C25.4 Endocrine pancreas	0.000	0.998	0.001
C67.2 Lateral wall of bladder	0.002	0.998	0.000
R23.4 Changes in skin texture	0.001	0.998	0.000
U89.8 Agent resistant to other single specified antibiotic	0.001	0.998	0.000
M99.59 Intervertebral disc stenosis of neural canal-Abdomen/other	0.000	0.998	0.001
M99.58 Intervertebral disc stenosis of neural canal-Rib cage	0.000	0.998	0.001
M99.57 Intervertebral disc stenosis of neural canal-Upper extremit	0.000	0.998	0.001
M99.56 Intervertebral disc stenosis of neural canal-Lower extremit	0.000	0.998	0.001
M99.55 Intervertebral disc stenosis of neural canal (Pelvic region)	0.000	0.998	0.001
M99.54 Intervertebral disc stenosis of neural canal (Sacral region)	0.000	0.998	0.001
M99.52 Intervertebral disc stenosis of neural canal (Thoracic region)	0.000	0.998	0.001
M99.51 Intervertebral disc stenosis of neural canal (Cervical region)	0.000	0.998	0.001
S92.0 Fracture of calcaneus	0.001	0.998	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.001	0.998	0.000
R23 Other skin changes	0.002	0.998	0.000
G71.9 Primary disorder of muscle, unspecified	0.001	0.999	0.000
G71.8 Other primary disorders of muscles	0.001	0.999	0.000
G71.2 Congenital myopathies	0.001	0.999	0.000
H10.1 Acute atopic conjunctivitis	0.000	0.999	0.001
T78.9 Adverse effect, unspecified	0.001	0.999	0.000
Z32.1 Pregnancy confirmed	0.001	0.999	0.000
H10.3 Acute conjunctivitis, unspecified	0.000	0.999	0.001
M31.1 Thrombotic microangiopathy	0.000	0.999	0.001
N92.6 Irregular menstruation, unspecified	0.000	0.999	0.001
S82.86 Maisonneuve's fracture	0.000	0.999	0.001
C67 Malignant neoplasm of bladder	0.001	0.999	0.000
S82.01 Fracture of patella (open)	0.000	0.999	0.001
E06.9 Thyroiditis, unspecified	0.001	0.999	0.000
S82.5 Fracture of medial malleolus	0.000	0.999	0.001
Z87.8 Personal history of other specified conditions	0.000	0.999	0.001
S92.50 Fracture of other toe (closed)	0.001	0.999	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.001	0.999	0.000
R90.0 Intracranial space-occupying lesion	0.000	0.999	0.001
T78 Adverse effects, not elsewhere classified	0.001	0.999	0.000
M99.50 Intervertebral disc stenosis of neural canal (Head region)	0.000	0.999	0.001
E14.1 With ketoacidosis	0.001	0.999	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.001	0.999	0.000
H13.3 Ocular pemphigoid	0.000	0.999	0.001
S82.50 Fracture of medial malleolus (closed)	0.000	0.999	0.001
C25.8 Overlapping lesion of pancreas	0.000	0.999	0.001
C25.7 Other parts of pancreas	0.000	0.999	0.001
G71.0 Muscular dystrophy	0.001	0.999	0.000
R23.8 Other and unspecified skin changes	0.001	0.999	0.000
B27.9 Infectious mononucleosis, unspecified	0.001	0.999	0.000
J35.1 Hypertrophy of tonsils	0.001	0.999	0.000
R23.2 Flushing	0.001	0.999	0.000
R52.9 Pain, unspecified	0.000	0.999	0.001
T78.8 Other adverse effects, not elsewhere classified	0.001	0.999	0.000
W17.2 School, other institution and public administrative area	0.001	0.999	0.000
M99.53 Intervertebral disc stenosis of neural canal (Lumbar region)	0.000	0.999	0.001
A08.4 Viral intestinal infection, unspecified	0.001	0.999	0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.001	0.999	0.000
M31.8 Other specified necrotising vasculopathies	0.000	0.999	0.001
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.999	0.001
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.001	0.999	0.000
M31 Other necrotising vasculopathies	0.000	0.999	0.001
S62.51 Fracture of thumb (open)	0.001	0.999	0.000
S82.21 Fracture of shaft of tibia (open)	0.000	0.999	0.001
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.999	0.001
S92.01 Fracture of calcaneus (open)	0.001	0.999	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.001	0.999	0.000
N64 Other disorders of breast	0.000	0.999	0.001
S12.90 Fracture of neck, part unspecified (closed)	0.001	0.999	0.000
C67.6 Ureteric orifice	0.001	0.999	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.001	0.999	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.999	0.001
R23.3 Spontaneous ecchymoses	0.001	0.999	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.999	0.001
B35.3 Tinea pedis	0.001	0.999	0.000
C67.7 Urachus	0.001	0.999	0.000
M31.7 Microscopic polyangiitis	0.000	0.999	0.001
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.000	0.999	0.001
S82.40 Fracture of fibula alone (closed)	0.001	0.999	0.000
C67.1 Dome of bladder	0.001	0.999	0.000
E14.0 With coma	0.001	0.999	0.000
N64.9 Disorder of breast, unspecified	0.000	0.999	0.001
N88.8 Other specified noninflammatory disorders of cervix uteri	0.001	0.999	0.000
Q10.0 Congenital ptosis	0.001	0.999	0.000
W17 Other fall from one level to another	0.001	0.999	0.000
C25.3 Pancreatic duct	0.000	0.999	0.001
D47.3 Essential (haemorrhagic) thrombocythaemia	0.001	0.999	0.000
Q14.1 Congenital malformation of retina	0.001	0.999	0.000
Z00.0 General medical examination	0.001	0.999	0.000
C67.8 Overlapping lesion of bladder	0.001	0.999	0.000
K38.8 Other specified diseases of appendix	0.001	0.999	0.000
N64.2 Atrophy of breast	0.000	0.999	0.001
N89.8 Other specified noninflammatory disorders of vagina	0.000	0.999	0.001
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.001	0.999	0.000
Q14 Congenital malformations of posterior segment of eye	0.001	0.999	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.001	0.999	0.000
C25.2 Tail of pancreas	0.000	0.999	0.001
F25.9 Schizoaffective disorder, unspecified	0.001	0.999	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.999	0.001
K63.3 Ulcer of intestine	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations