TreeWAS – Variant ID: rs4947962

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R79.8 Other specified abnormal findings of blood chemistry	0.139	0.861	0.000
R79 Other abnormal findings of blood chemistry	0.085	0.915	0.000
R79.0 Abnormal level of blood mineral	0.076	0.924	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.046	0.953	0.000
I35.0 Aortic (valve) stenosis	0.044	0.956	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.042	0.958	0.000
I35 Nonrheumatic aortic valve disorders	0.042	0.958	0.000
I35.9 Aortic valve disorder, unspecified	0.037	0.963	0.000
I35.8 Other aortic valve disorders	0.031	0.969	0.000
I35.1 Aortic (valve) insufficiency	0.027	0.973	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.024	0.976	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.019	0.981	0.000
R78 Findings of drugs and other substances, not normally found in blood	0.018	0.982	0.000
R76 Other abnormal immunological findings in serum	0.018	0.982	0.000
R71 Abnormality of red blood cells	0.018	0.982	0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.017	0.983	0.000
R77 Other abnormalities of plasma proteins	0.016	0.983	0.000
R74 Abnormal serum enzyme levels	0.015	0.984	0.000
R73 Elevated blood glucose level	0.015	0.985	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.015	0.985	0.000
Z85.4 Personal history of malignant neoplasm of genital organs	0.000	0.985	0.015
R76.9 Abnormal immunological finding in serum, unspecified	0.014	0.985	0.000
R78.8 Finding of other specified substances, not normally found in blood	0.014	0.985	0.000
R70.1 Abnormal plasma viscosity	0.014	0.986	0.000
R76.0 Raised antibody titer	0.014	0.986	0.000
R78.9 Finding of unspecified substance, not normally found in blood	0.013	0.987	0.000
R78.7 Finding of abnormal level of heavy metals in blood	0.013	0.987	0.000
R78.6 Finding of steroid agent in blood	0.013	0.987	0.000
R78.5 Finding of psychotropic drug in blood	0.013	0.987	0.000
R78.4 Finding of other drugs of addictive potential in blood	0.013	0.987	0.000
R78.3 Finding of hallucinogen in blood	0.013	0.987	0.000
R78.2 Finding of cocaine in blood	0.013	0.987	0.000
R78.1 Finding of opiate drug in blood	0.013	0.987	0.000
R77.9 Abnormality of plasma protein, unspecified	0.013	0.987	0.000
R76.2 False-positive serological test for syphilis	0.013	0.987	0.000
R76.1 Abnormal reaction to tuberculin test	0.013	0.987	0.000
R78.0 Finding of alcohol in blood	0.013	0.987	0.000
R77.0 Abnormality of albumin	0.013	0.987	0.000
R74.8 Abnormal levels of other serum enzymes	0.012	0.987	0.000
R77.2 Abnormality of alphafetoprotein	0.012	0.988	0.000
R77.1 Abnormality of globulin	0.011	0.988	0.000
R73.0 Abnormal glucose tolerance test	0.011	0.988	0.000
R76.8 Other specified abnormal immunological findings in serum	0.011	0.989	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.011	0.989	0.000
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.010	0.990	0.000
R77.8 Other specified abnormalities of plasma proteins	0.010	0.990	0.000
R74.9 Abnormal level of unspecified serum enzyme	0.009	0.990	0.000
H33.0 Retinal detachment with retinal break	0.000	0.992	0.008
R73.9 Hyperglycaemia, unspecified	0.008	0.992	0.000
S82.50 Fracture of medial malleolus (closed)	0.000	0.993	0.007
J43.9 Emphysema, unspecified	0.000	0.993	0.007
O02.1 Missed abortion	0.000	0.994	0.006
Z51.3 Blood transfusion without reported diagnosis	0.006	0.994	0.000
M20.4 Other hammer toe(s) (acquired)	0.006	0.994	0.000
R06.0 Dyspnoea	0.000	0.994	0.006
S82.5 Fracture of medial malleolus	0.000	0.995	0.005
M54.39 Sciatica (Site unspecified)	0.005	0.995	0.000
Y95 Nosocomial condition	0.000	0.995	0.005
D36.1 Peripheral nerves and autonomic nervous system	0.005	0.995	0.000
S83.2 Tear of meniscus, current	0.000	0.995	0.005
S82.51 Fracture of medial malleolus (open)	0.000	0.996	0.004
S81.8 Open wound of other parts of lower leg	0.000	0.996	0.004
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.996	0.004
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.996	0.004
S81 Open wound of lower leg	0.000	0.996	0.004
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.996	0.004
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.996	0.004
J43 Emphysema	0.000	0.996	0.004
S82 Fracture of lower leg, including ankle	0.000	0.996	0.004
S80-S89 Injuries to the knee and lower leg	0.000	0.996	0.004
M54.3 Sciatica	0.004	0.996	0.000
Z94.0 Kidney transplant status	0.000	0.996	0.004
S82.2 Fracture of shaft of tibia	0.000	0.996	0.004
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.996	0.004
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.004	0.996	0.000
M54.36 Sciatica (Lumbar region)	0.004	0.996	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.996	0.004
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.004	0.996	0.000
S81.9 Open wound of lower leg, part unspecified	0.000	0.996	0.003
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.996	0.003
J43.8 Other emphysema	0.000	0.997	0.003
S86 Injury of muscle and tendon at lower leg level	0.000	0.997	0.003
S83.1 Dislocation of knee	0.000	0.997	0.003
M80.9 Unspecified osteoporosis with pathological fracture	0.003	0.997	0.000
J43.2 Centrilobular emphysema	0.000	0.997	0.003
S81.7 Multiple open wounds of lower leg	0.000	0.997	0.003
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.003	0.997	0.000
R22.2 Localised swelling, mass and lump, trunk	0.000	0.997	0.003
S82.9 Fracture of lower leg, part unspecified	0.000	0.997	0.003
S87 Crushing injury of lower leg	0.000	0.997	0.003
M54.30 Sciatica (Multiple sites in spine)	0.003	0.997	0.000
S89 Other and unspecified injuries of lower leg	0.000	0.997	0.003
S85 Injury of blood vessels at lower leg level	0.000	0.997	0.003
J43.1 Panlobular emphysema	0.000	0.997	0.003
J43.0 MacLeod's syndrome	0.000	0.997	0.003
Q54.9 Hypospadias, unspecified	0.003	0.997	0.000
S88 Traumatic amputation of lower leg	0.000	0.997	0.003
S82.7 Multiple fractures of lower leg	0.000	0.997	0.003
S82.3 Fracture of lower end of tibia	0.000	0.997	0.003
S83.7 Injury to multiple structures of knee	0.000	0.997	0.003
S83.0 Dislocation of patella	0.000	0.997	0.003
M54.35 Sciatica (Thoracolumbar region)	0.003	0.997	0.000
M54.34 Sciatica-Thoracic	0.003	0.997	0.000
M54.33 Sciatica-Cervicothoracic	0.003	0.997	0.000
M54.32 Sciatica-Cervical	0.003	0.997	0.000
M54.31 Sciatica-Occipit-atl-axl	0.003	0.997	0.000
S82.4 Fracture of fibula alone	0.000	0.997	0.003
S83.3 Tear of articular cartilage of knee, current	0.000	0.997	0.003
S84 Injury of nerves at lower leg level	0.000	0.997	0.003
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.997	0.003
Q54 Hypospadias	0.003	0.997	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.997	0.003
O02 Other abnormal products of conception	0.000	0.997	0.003
R57.2 Septic shock	0.000	0.997	0.003
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
S81.0 Open wound of knee	0.000	0.997	0.003
S86.0 Injury of Achilles tendon	0.000	0.997	0.003
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.997	0.003
S82.21 Fracture of shaft of tibia (open)	0.000	0.997	0.003
S82.6 Fracture of lateral malleolus	0.000	0.997	0.003
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.003	0.997	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.003	0.997	0.000
Q54.0 Hypospadias, balanic	0.003	0.997	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.997	0.003
S82.0 Fracture of patella	0.000	0.997	0.003
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.997	0.002
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.997	0.002
M54.37 Sciatica (Lumbosacral region)	0.002	0.997	0.000
S89.9 Unspecified injury of lower leg	0.000	0.997	0.003
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.997	0.002
S82.1 Fracture of upper end of tibia	0.000	0.997	0.002
S87.0 Crushing injury of knee	0.000	0.997	0.002
S89.7 Multiple injuries of lower leg	0.000	0.997	0.002
S89.1 Other specified injuries of lower leg	0.000	0.997	0.002
S89.0 Multiple injuries of lower leg	0.000	0.997	0.002
Q54.1 Hypospadias, penile	0.002	0.997	0.000
S89.8 Other specified injuries of lower leg	0.000	0.997	0.002
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.997	0.002
S85.8 Injury of other blood vessels at lower leg level	0.000	0.997	0.002
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.997	0.002
S85.5 Injury of popliteal vein	0.000	0.997	0.002
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.997	0.002
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.997	0.002
S85.2 Injury of peroneal artery	0.000	0.997	0.002
S85.0 Injury of popliteal artery	0.000	0.997	0.002
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.997	0.002
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.997	0.002
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.997	0.002
S88.0 Traumatic amputation at knee level	0.000	0.997	0.002
S82.31 Fracture of lower end of tibia (open)	0.000	0.998	0.002
S82.61 Fracture of lateral malleolus (open)	0.000	0.998	0.002
S82.71 Multiple fractures of lower leg (open)	0.000	0.998	0.002
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.998	0.002
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.998	0.002
S82.41 Fracture of fibula alone (open)	0.000	0.998	0.002
S82.70 Multiple fractures of lower leg (closed)	0.000	0.998	0.002
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.998	0.002
S84.8 Injury of other nerves at lower leg level	0.000	0.998	0.002
S84.7 Injury of multiple nerves at lower leg level	0.000	0.998	0.002
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.998	0.002
S84.0 Injury of tibial nerve at lower leg level	0.000	0.998	0.002
S82.30 Fracture of lower end of tibia (closed)	0.000	0.998	0.002
Z95.2 Presence of prosthetic heart valve	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.998	0.002
M06.0 Seronegative rheumatoid arthritis	0.000	0.998	0.002
Q54.4 Congenital chordee	0.002	0.998	0.000
Q54.3 Hypospadias, perineal	0.002	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.998	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.002	0.998	0.000
Q54.8 Other hypospadias	0.002	0.998	0.000
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
O02.8 Other specified abnormal products of conception	0.000	0.998	0.002
Q50.4 Embryonic cyst of Fallopian tube	0.002	0.998	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.998	0.002
I74.5 Embolism and thrombosis of iliac artery	0.000	0.998	0.002
R16.1 Splenomegaly, not elsewhere classified	0.002	0.998	0.000
M54.57 Low back pain (Lumbosacral region)	0.002	0.998	0.000
S86.00 Unspecified injury of Achilles tendon	0.000	0.998	0.002
O02.9 Abnormal product of conception, unspecified	0.000	0.998	0.002
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.998	0.002
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.000	0.998	0.002
S82.40 Fracture of fibula alone (closed)	0.000	0.998	0.002
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
Q23.1 Congenital insufficiency of aortic valve	0.002	0.998	0.000
R57.1 Hypovolaemic shock	0.000	0.998	0.002
O02.0 Blighted ovum and nonhydatidiform mole	0.000	0.998	0.002
Q50.5 Embryonic cyst of broad ligament	0.002	0.998	0.000
S80 Superficial injury of lower leg	0.000	0.998	0.002
M10.99 Gout, unspecified (Site unspecified)	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
S82.11 Fracture of upper end of tibia (open)	0.000	0.998	0.002
K14.9 Disease of tongue, unspecified	0.000	0.998	0.002
Q53 Undescended testicle	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
S82.00 Fracture of patella (closed)	0.000	0.998	0.002
H81.0 Meniere's disease	0.002	0.998	0.000
Q50.0 Congenital absence of ovary	0.002	0.998	0.000
T31.0 Burns involving less than 10% of body surface	0.002	0.998	0.000
H33 Retinal detachments and breaks	0.000	0.998	0.002
R57 Shock, not elsewhere classified	0.000	0.998	0.002
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.002	0.998	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.002	0.998	0.000
Q50.3 Other congenital malformations of ovary	0.002	0.998	0.000
Q50.2 Congenital torsion of ovary	0.002	0.998	0.000
Q50.1 Developmental ovarian cyst	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.998	0.002
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.998	0.002
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.998	0.002
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.000	0.998	0.002
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.998	0.002
S82.01 Fracture of patella (open)	0.000	0.998	0.002
B18.2 Chronic viral hepatitis C	0.000	0.998	0.002
Q51.2 Other doubling of uterus	0.002	0.998	0.000
R57.0 Cardiogenic shock	0.000	0.998	0.002
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.998	0.002
H33.3 Retinal breaks without detachment	0.000	0.998	0.002
N30.9 Cystitis, unspecified	0.000	0.998	0.002
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.998	0.002
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
S82.8 Fractures of other parts of lower leg	0.000	0.998	0.002
Z36.8 Other antenatal screening	0.000	0.998	0.002
D36 Benign neoplasm of other and unspecified sites	0.002	0.998	0.000
Y98 Lifestyle-related condition	0.000	0.998	0.002
Y97 Environmental-pollution-related condition	0.000	0.998	0.002
Y96 Work-related condition	0.000	0.998	0.002
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.998	0.002
H33.4 Traction detachment of retina	0.000	0.998	0.002
M80 Osteoporosis with pathological fracture	0.002	0.998	0.000
Q52.1 Doubling of vagina	0.002	0.998	0.000
Y85.0 Sequelae of motor-vehicle accident	0.000	0.998	0.002
Q51.3 Bicornate uterus	0.002	0.998	0.000
R87.6 Abnormal cytological findings	0.000	0.998	0.002
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.998	0.002
S80.8 Other superficial injuries of lower leg	0.000	0.998	0.002
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.002	0.998	0.000
Q52.5 Fusion of labia	0.002	0.998	0.000
Q53.1 Undescended testicle, unilateral	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.000	0.998	0.002
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
Q53.2 Undescended testicle, bilateral	0.002	0.998	0.000
Y90.7 Blood alcohol level of 200-239 mg/100 ml	0.000	0.998	0.002
Y91 Evidence of alcohol involvement determined by level of intoxication	0.000	0.998	0.002
I63.9 Cerebral infarction, unspecified	0.002	0.998	0.000
Y90.6 Blood alcohol level of 120-199 mg/100 ml	0.000	0.998	0.002
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.002	0.998	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.002	0.998	0.000
Q51.6 Embryonic cyst of cervix	0.002	0.998	0.000
Q51.5 Agenesis and aplasia of cervix	0.002	0.998	0.000
Q51.4 Unicornate uterus	0.002	0.998	0.000
Q51.0 Agenesis and aplasia of uterus	0.002	0.998	0.000
Q53.0 Ectopic testis	0.002	0.998	0.000
R57.8 Other shock	0.000	0.998	0.002
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.002	0.998	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.001	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.001	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.001	0.998	0.000
Q52.3 Imperforate hymen	0.001	0.998	0.000
Q52.2 Congenital rectovaginal fistula	0.001	0.998	0.000
Q52.0 Congenital absence of vagina	0.001	0.998	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.001	0.998	0.000
Q55.6 Other congenital malformations of penis	0.001	0.998	0.000
S80.7 Multiple superficial injuries of lower leg	0.000	0.998	0.001
Y85.9 Sequelae of other and unspecified transport accidents	0.000	0.998	0.002
Y90.9 Presence of alcohol in blood, level not specified	0.000	0.998	0.001
Y90.5 Blood alcohol level of 100-119 mg/100 ml	0.000	0.998	0.001
Y90.4 Blood alcohol level of 80-99 mg/100 ml	0.000	0.998	0.001
Y90.3 Blood alcohol level of 60-79 mg/100 ml	0.000	0.998	0.001
Y90.2 Blood alcohol level of 40-59 mg/100 ml	0.000	0.998	0.001
Y90.1 Blood alcohol level of 20-39 mg/100 ml	0.000	0.998	0.001
Y90.0 Blood alcohol level of less than 20 mg/100 ml	0.000	0.998	0.001
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.998	0.002
H93.1 Tinnitus	0.000	0.998	0.002
Q56.4 Indeterminate sex, unspecified	0.001	0.998	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.001	0.998	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.001	0.998	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.001	0.998	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.001	0.998	0.000
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
Q53.9 Undescended testicle, unspecified	0.001	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.001	0.998	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.998	0.002
N94.1 Dyspareunia	0.000	0.998	0.002
Q55.9 Congenital malformation of male genital organ, unspecified	0.001	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.001	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.001	0.998	0.000
Q55.3 Atresia of vas deferens	0.001	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.001	0.998	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.002	0.998	0.000
S82.86 Maisonneuve's fracture	0.000	0.998	0.001
D36.9 Benign neoplasm of unspecified site	0.001	0.998	0.000
R57.9 Shock, unspecified	0.000	0.998	0.001
Y90.8 Blood alcohol level of 240 mg/100 ml or more	0.000	0.998	0.001
D36.7 Other specified sites	0.002	0.998	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.001	0.998	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.001	0.998	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.001	0.998	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.001	0.998	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.002	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.001	0.998	0.000
Q52.4 Other congenital malformations of vagina	0.001	0.998	0.000
Z36.9 Antenatal screening, unspecified	0.000	0.998	0.002
S82.81 Fractures of other parts of lower leg (open)	0.000	0.998	0.001
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.998	0.002
S80.9 Superficial injury of lower leg, unspecified	0.000	0.998	0.002
D06.9 Cervix, unspecified	0.000	0.998	0.002
M54.6 Pain in thoracic spine	0.002	0.998	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.001	0.998	0.000
Q55.0 Absence and aplasia of testis	0.001	0.998	0.000
M80.8 Other osteoporosis with pathological fracture	0.001	0.998	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.998	0.002
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.998	0.002
S82.10 Fracture of upper end of tibia (closed)	0.000	0.998	0.001
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.998	0.001
I74.8 Embolism and thrombosis of other arteries	0.000	0.998	0.001
Y91.3 Very severe alcohol intoxication	0.000	0.998	0.001
Y91.2 Severe alcohol intoxication	0.000	0.998	0.001
Y91.1 Moderate alcohol intoxication	0.000	0.998	0.001
Y91.0 Mild alcohol intoxication	0.000	0.998	0.001
I63 Cerebral infarction	0.002	0.998	0.000
R22.1 Localised swelling, mass and lump, neck	0.000	0.998	0.002
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.998	0.001
E28 Ovarian dysfunction	0.000	0.998	0.001
M54 Dorsalgia	0.002	0.998	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.001	0.998	0.000
Z94.2 Lung transplant status	0.000	0.998	0.001
D36.0 Lymph nodes	0.001	0.998	0.000
E21.2 Other hyperparathyroidism	0.000	0.998	0.001
I63.8 Other cerebral infarction	0.001	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.001	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.001	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.999	0.001
E28.3 Primary ovarian failure	0.000	0.999	0.001
Q51.8 Other congenital malformations of uterus and cervix	0.001	0.999	0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.001	0.999	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.001	0.999	0.000
S80.0 Contusion of knee	0.000	0.999	0.001
Z94 Transplanted organ and tissue status	0.000	0.999	0.001
M54.55 Low back pain (Thoracolumbar region)	0.001	0.999	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
C16.0 Cardia	0.000	0.999	0.001
H10.9 Conjunctivitis, unspecified	0.000	0.999	0.001
H93.9 Disorder of ear, unspecified	0.000	0.999	0.001
M54.5 Low back pain	0.001	0.999	0.000
Y85 Sequelae of transport accidents	0.000	0.999	0.001
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.001	0.999	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.001	0.999	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.001	0.999	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.001	0.999	0.000
H33.1 Retinoschisis and retinal cysts	0.000	0.999	0.001
M50.3 Other cervical disk degeneration	0.000	0.999	0.001
M54.1 Radiculopathy	0.001	0.999	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
E21.4 Other specified disorders of parathyroid gland	0.000	0.999	0.001
K14.0 Glossitis	0.000	0.999	0.001
M80.0 Postmenopausal osteoporosis with pathological fracture	0.001	0.999	0.000
Y57.5 X-ray contrast media	0.000	0.999	0.001
M54.69 Pain in thoracic spine-Site unspe	0.001	0.999	0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.001	0.999	0.000
M54.67 Pain in thoracic spine-Lumbosacral	0.001	0.999	0.000
M54.66 Pain in thoracic spine-Lumbar	0.001	0.999	0.000
M54.62 Pain in thoracic spine-Cervical	0.001	0.999	0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.001	0.999	0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.001	0.999	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.001	0.999	0.000
Y91.9 Alcohol involvement, not otherwise specified	0.000	0.999	0.001
I74 Arterial embolism and thrombosis	0.000	0.999	0.001
Q85 Phakomatoses, not elsewhere classified	0.001	0.999	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.001	0.999	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.001	0.999	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.001	0.999	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.999	0.001
M54.8 Other dorsalgia	0.001	0.999	0.000
I60 Subarachnoid haemorrhage	0.000	0.999	0.001
M54.89 Other dorsalgia (Site unspecified)	0.001	0.999	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.999	0.001
E28.9 Ovarian dysfunction, unspecified	0.000	0.999	0.001
E28.8 Other ovarian dysfunction	0.000	0.999	0.001
E28.1 Androgen excess	0.000	0.999	0.001
E28.0 Oestrogen excess	0.000	0.999	0.001
M54.0 Panniculitis affecting regions of neck and back	0.001	0.999	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M54.16 Radiculopathy (Lumbar region)	0.001	0.999	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.001	0.999	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.999	0.001
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.999	0.001
Q23.0 Congenital stenosis of aortic valve	0.001	0.999	0.000
Q76.0 Spina bifida occulta	0.001	0.999	0.000
W25.9 Unspecified place	0.001	0.999	0.000
Z94.9 Transplanted organ and tissue status, unspecified	0.000	0.999	0.001
M54.10 Radiculopathy (Multiple sites in spine)	0.001	0.999	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.999	0.001
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.001	0.999	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.001	0.999	0.000
Q23.4 Hypoplastic left heart syndrome	0.001	0.999	0.000
Q23.2 Congenital mitral stenosis	0.001	0.999	0.000
Q85.1 Tuberous sclerosis	0.001	0.999	0.000
R59.0 Localised enlarged lymph nodes	0.000	0.999	0.001
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.999	0.001
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.001	0.999	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
S82.60 Fracture of lateral malleolus (closed)	0.000	0.999	0.001
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.001	0.999	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.999	0.001
Q05.9 Spina bifida, unspecified	0.001	0.999	0.000
R25.2 Cramp and spasm	0.001	0.999	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.001	0.999	0.000
M54.14 Radiculopathy (Thoracic region)	0.001	0.999	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.001	0.999	0.000
M54.53 Low back pain-Cervicothoracic	0.001	0.999	0.000
M54.51 Low back pain-Occipit-atl-axl	0.001	0.999	0.000
M54.86 Other dorsalgia (Lumbar region)	0.001	0.999	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.999	0.001
W18.3 Sports and athletics area	0.001	0.999	0.000
Z94.6 Bone transplant status	0.000	0.999	0.001
Z94.3 Heart and lungs transplant status	0.000	0.999	0.001
M54.80 Other dorsalgia (Multiple sites in spine)	0.001	0.999	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.001	0.999	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.001	0.999	0.000
Y57.6 Other diagnostic agents	0.000	0.999	0.001
M54.52 Low back pain-Cervical	0.001	0.999	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.999	0.001
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.999	0.001
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.999	0.001
K59.1 Functional diarrhoea	0.001	0.999	0.000
K14 Diseases of tongue	0.000	0.999	0.001
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.001	0.999	0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations