TreeWAS – Variant ID: rs4950928

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.811	0.189
D69 Purpura and other haemorrhagic conditions	0.000	0.889	0.111
D69.5 Secondary thrombocytopenia	0.000	0.905	0.095
D69.1 Qualitative platelet defects	0.000	0.910	0.090
D70 Agranulocytosis	0.000	0.911	0.089
D69.4 Other primary thrombocytopenia	0.000	0.916	0.084
D69.2 Other nonthrombocytopenic purpura	0.000	0.920	0.080
D69.9 Haemorrhagic condition, unspecified	0.000	0.921	0.079
D69.8 Other specified haemorrhagic conditions	0.000	0.922	0.078
D69.0 Allergic purpura	0.000	0.933	0.067
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.941	0.059
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.946	0.054
M06.9 Rheumatoid arthritis, unspecified	0.047	0.953	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.045	0.955	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.956	0.044
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.044	0.956	0.000
M06 Other rheumatoid arthritis	0.043	0.957	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.958	0.042
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.958	0.041
D67 Hereditary factor IX deficiency	0.000	0.959	0.041
M06.0 Seronegative rheumatoid arthritis	0.040	0.960	0.000
D66 Hereditary factor VIII deficiency	0.000	0.960	0.040
D74 Methaemoglobinaemia	0.000	0.961	0.039
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.961	0.039
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.961	0.039
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.039	0.961	0.000
M06.4 Inflammatory polyarthropathy	0.039	0.961	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.039	0.961	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.037	0.963	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.037	0.963	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.036	0.964	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.036	0.964	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.036	0.964	0.000
D73 Diseases of spleen	0.000	0.966	0.034
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.034	0.966	0.000
D75 Other diseases of blood and blood-forming organs	0.000	0.966	0.034
D76.3 Other histiocytosis syndromes	0.000	0.967	0.033
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.033	0.967	0.000
D55-D59 Haemolytic anaemias	0.000	0.967	0.032
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.032	0.968	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.032	0.968	0.000
M06.1 Adult-onset Still's disease	0.031	0.969	0.000
D69.6 Thrombocytopenia, unspecified	0.000	0.969	0.031
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.031	0.969	0.000
M06.2 Rheumatoid bursitis	0.031	0.969	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.030	0.970	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.970	0.030
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.970	0.030
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.970	0.030
M06.8 Other specified rheumatoid arthritis	0.030	0.970	0.000
M06.3 Rheumatoid nodule	0.029	0.971	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.029	0.971	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.029	0.971	0.000
D74.9 Methaemoglobinaemia, unspecified	0.000	0.972	0.028
D74.8 Other methaemoglobinaemias	0.000	0.972	0.028
D74.0 Congenital methaemoglobinaemia	0.000	0.972	0.028
M06.48 Inflammatory polyarthropathy (Other)	0.028	0.972	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.028	0.972	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.028	0.972	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.028	0.972	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.028	0.972	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.028	0.972	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.028	0.972	0.000
D73.1 Hypersplenism	0.000	0.972	0.028
D56 Thalassaemia	0.000	0.972	0.027
D75.2 Essential thrombocytosis	0.000	0.972	0.027
M06.04 Seronegative rheumatoid arthritis (Hand)	0.027	0.972	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.027	0.973	0.000
D73.4 Cyst of spleen	0.000	0.973	0.027
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.027	0.973	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.027	0.973	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.027	0.973	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.973	0.027
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.026	0.974	0.000
D73.9 Disease of spleen, unspecified	0.000	0.975	0.025
D72 Other disorders of white blood cells	0.000	0.975	0.025
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.975	0.025
D58 Other hereditary haemolytic anaemias	0.000	0.975	0.025
D73.2 Chronic congestive splenomegaly	0.000	0.976	0.024
D68 Other coagulation defects	0.000	0.976	0.024
M06.10 Adult-onset Still's disease (Multiple sites)	0.024	0.976	0.000
D56.1 Beta thalassaemia	0.000	0.976	0.024
D55 Anaemia due to enzyme disorders	0.000	0.976	0.023
M06.30 Rheumatoid nodule (Multiple sites)	0.023	0.977	0.000
D57 Sickle-cell disorders	0.000	0.977	0.023
M06.34 Rheumatoid nodule (Hand)	0.023	0.977	0.000
M06.18 Adult-onset Still's disease (Other)	0.023	0.977	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.023	0.977	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.023	0.977	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.023	0.977	0.000
M06.14 Adult-onset Still's disease (Hand)	0.023	0.977	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.023	0.977	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.023	0.977	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.023	0.977	0.000
D50-D53 Nutritional anaemias	0.000	0.977	0.023
D73.5 Infarction of spleen	0.000	0.978	0.022
M06.29 Rheumatoid bursitis (Site unspecified)	0.022	0.978	0.000
M06.28 Rheumatoid bursitis (Other)	0.022	0.978	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.022	0.978	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.022	0.978	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.022	0.978	0.000
M06.24 Rheumatoid bursitis (Hand)	0.022	0.978	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.022	0.978	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.022	0.978	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.022	0.978	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.022	0.978	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.022	0.978	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.978	0.022
D56.3 Thalassaemia trait	0.000	0.978	0.022
M06.88 Other specified rheumatoid arthritis (Other)	0.022	0.978	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.022	0.978	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.022	0.978	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.022	0.978	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.022	0.978	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.022	0.978	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.022	0.978	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.022	0.978	0.000
D73.3 Abscess of spleen	0.000	0.978	0.022
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.021	0.978	0.000
O20.0 Threatened abortion	0.022	0.978	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.021	0.979	0.000
M06.38 Rheumatoid nodule (Other)	0.021	0.979	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.021	0.979	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.021	0.979	0.000
D75.0 Familial erythrocytosis	0.000	0.979	0.021
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.021	0.979	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.979	0.021
M06.33 Rheumatoid nodule (Forearm)	0.021	0.979	0.000
D58.0 Hereditary spherocytosis	0.000	0.979	0.021
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.979	0.021
D73.8 Other diseases of spleen	0.000	0.979	0.021
D56.8 Other thalassaemias	0.000	0.980	0.020
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.000	0.980	0.020
D56.2 Delta-beta thalassaemia	0.000	0.980	0.020
D56.0 Alpha thalassaemia	0.000	0.980	0.020
M06.32 Rheumatoid nodule (Upper arm)	0.020	0.980	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.980	0.020
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.980	0.020
M06.36 Rheumatoid nodule (Lower leg)	0.019	0.981	0.000
D53 Other nutritional anaemias	0.000	0.981	0.019
D56.9 Thalassaemia, unspecified	0.000	0.981	0.019
M06.37 Rheumatoid nodule (Ankle and foot)	0.018	0.981	0.000
D72.9 Disorder of white blood cells, unspecified	0.000	0.982	0.018
D72.0 Genetic anomalies of leukocytes	0.000	0.982	0.018
D58.8 Other specified hereditary haemolytic anaemias	0.000	0.982	0.018
D58.1 Hereditary elliptocytosis	0.000	0.982	0.018
D68.4 Acquired coagulation factor deficiency	0.000	0.982	0.018
D73.0 Hyposplenism	0.000	0.982	0.018
D68.0 Von Willebrand's disease	0.000	0.982	0.018
D58.2 Other haemoglobinopathies	0.000	0.982	0.017
D68.1 Hereditary factor XI deficiency	0.000	0.983	0.017
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.983	0.017
D55.8 Other anaemias due to enzyme disorders	0.000	0.983	0.017
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.983	0.017
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.983	0.017
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.983	0.017
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.983	0.017
D57.1 Sickle-cell anaemia without crisis	0.000	0.983	0.017
D57.8 Other sickle-cell disorders	0.000	0.983	0.017
D57.2 Double heterozygous sickling disorders	0.000	0.983	0.017
D57.0 Sickle-cell anaemia with crisis	0.000	0.983	0.017
C82.4 Follicular lymphoma grade IIIb	0.000	0.983	0.017
D57.3 Sickle-cell trait	0.000	0.983	0.016
D53.9 Nutritional anaemia, unspecified	0.000	0.984	0.016
D58.9 Hereditary haemolytic anaemia, unspecified	0.000	0.984	0.016
D68.9 Coagulation defect, unspecified	0.000	0.984	0.016
C82.3 Follicular lymphoma grade IIIa	0.000	0.984	0.016
D59 Acquired haemolytic anaemia	0.000	0.985	0.015
C82.6 Cutaneous follicle centre lymphoma	0.000	0.985	0.015
C82.5 Diffuse follicle centre lymphoma	0.000	0.985	0.015
D72.8 Other specified disorders of white blood cells	0.000	0.985	0.015
D60-D64 Aplastic and other anaemias	0.000	0.985	0.015
C82.0 Small cleaved cell, follicular	0.000	0.986	0.014
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.986	0.014
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.986	0.014
D53.8 Other specified nutritional anaemias	0.000	0.986	0.014
D53.2 Scorbutic anaemia	0.000	0.986	0.014
D53.0 Protein deficiency anaemia	0.000	0.986	0.014
D52 Folate deficiency anaemia	0.000	0.986	0.014
C82.2 Large cell, follicular	0.000	0.986	0.014
D68.5 Primary Thrombophilia	0.000	0.986	0.014
D68.6 Other Thrombophilia	0.000	0.987	0.013
D51 Vitamin B12 deficiency anaemia	0.000	0.988	0.012
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.988	0.012
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.988	0.012
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.988	0.012
C85.1 B-cell lymphoma, unspecified	0.000	0.988	0.012
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.988	0.012
T36-T50 Poisoning by drugs, medicaments and biological substances	0.012	0.988	0.000
D59.8 Other acquired haemolytic anaemias	0.000	0.989	0.011
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.989	0.011
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.989	0.011
D59.3 Haemolytic-uraemic syndrome	0.000	0.989	0.011
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.989	0.011
Z93.1 Gastrostomy status	0.000	0.989	0.011
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.011	0.989	0.000
K11.8 Other diseases of salivary glands	0.000	0.989	0.011
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.011	0.989	0.000
D50 Iron deficiency anaemia	0.000	0.989	0.011
D63.0 Anaemia in neoplastic disease	0.000	0.989	0.011
D72.1 Eosinophilia	0.001	0.989	0.010
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.989	0.011
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.989	0.010
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.989	0.011
T40.2 Other opioids	0.011	0.989	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.990	0.010
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.010	0.990	0.000
T43.2 Other and unspecified antidepressants	0.010	0.990	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.990	0.010
K11 Diseases of salivary glands	0.000	0.990	0.010
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.010	0.990	0.000
D52.8 Other folate deficiency anaemias	0.000	0.990	0.010
D52.1 Drug-induced folate deficiency anaemia	0.000	0.990	0.010
D52.0 Dietary folate deficiency anaemia	0.000	0.990	0.010
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.990	0.010
D75.1 Secondary polycythaemia	0.000	0.990	0.010
C86 Other specified types of T/NK-cell lymphoma	0.000	0.990	0.010
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.010	0.990	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.990	0.010
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.990	0.010
K11.5 Sialolithiasis	0.000	0.990	0.010
K11.9 Disease of salivary gland, unspecified	0.000	0.990	0.010
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.990	0.010
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.990	0.010
T46 Poisoning by agents primarily affecting the cardiovascular system	0.009	0.991	0.000
D68.8 Other specified coagulation defects	0.000	0.991	0.009
C94 Other leukaemias of specified cell type	0.000	0.991	0.009
R09.1 Pleurisy	0.009	0.991	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.009	0.991	0.000
C84.5 Other and unspecified T-cell lymphomas	0.000	0.991	0.009
D51.2 Transcobalamin II deficiency	0.000	0.991	0.009
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.991	0.009
C83.1 Small cleaved cell (diffuse)	0.000	0.991	0.009
T36 Poisoning by systemic antibiotics	0.009	0.991	0.000
T40.3 Methadone	0.009	0.991	0.000
T40.4 Other synthetic narcotics	0.009	0.991	0.000
T40.5 Cocaine	0.009	0.991	0.000
T38.1 Thyroid hormones and substitutes	0.009	0.991	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.009	0.991	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.991	0.009
T43.3 Phenothiazine antipsychotics and neuroleptics	0.009	0.991	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.009	0.991	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.009	0.991	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.000	0.991	0.009
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.009	0.991	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.000	0.991	0.009
T41 Poisoning by anaesthetics and therapeutic gases	0.008	0.991	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.991	0.008
C85.0 Lymphosarcoma	0.000	0.991	0.008
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.008	0.991	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.009	0.991	0.000
T43.6 Psychostimulants with abuse potential	0.008	0.991	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.008	0.991	0.000
C84.4 Peripheral T-cell lymphoma	0.000	0.992	0.008
C84.0 Mycosis fungoides	0.000	0.992	0.008
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.992	0.008
T40.6 Other and unspecified narcotics	0.008	0.992	0.000
D12.3 Transverse colon	0.008	0.992	0.000
D59.1 Other autoimmune haemolytic anaemias	0.000	0.992	0.008
T50.6 Antidotes and chelating agents, not elsewhere classified	0.008	0.992	0.000
K26.0 Acute with haemorrhage	0.000	0.992	0.008
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.008	0.992	0.000
T40.8 Lysergide [LSD]	0.008	0.992	0.000
T40.7 Cannabis (derivatives)	0.008	0.992	0.000
T40.0 Opium	0.008	0.992	0.000
C93 Monocytic leukaemia	0.000	0.992	0.008
C88 Malignant immunoproliferative diseases	0.000	0.992	0.008
D80-D89 Certain disorders involving the immune mechanism	0.001	0.992	0.007
K11.3 Abscess of salivary gland	0.000	0.992	0.008
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.008	0.992	0.000
M05-M14 Inflammatory polyarthropathies	0.008	0.992	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.008	0.992	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.992	0.008
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.008	0.992	0.000
C83.0 Small cell (diffuse)	0.000	0.992	0.008
T38.8 Other and unspecified hormones and their synthetic substitutes	0.008	0.992	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.008	0.992	0.000
K11.1 Hypertrophy of salivary gland	0.000	0.992	0.008
K11.7 Disturbances of salivary secretion	0.000	0.992	0.008
M07.3 Other psoriatic arthropathies	0.008	0.992	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.008	0.992	0.000
T38.5 Other oestrogens and progestogens	0.008	0.992	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.008	0.992	0.000
D60.8 Other acquired pure red cell aplasias	0.000	0.992	0.008
D60.1 Transient acquired pure red cell aplasia	0.000	0.992	0.008
D60.0 Chronic acquired pure red cell aplasia	0.000	0.992	0.008
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.008	0.992	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.000	0.992	0.008
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.000	0.992	0.008
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.000	0.992	0.008
C84.3 Lymphoepithelioid lymphoma	0.000	0.992	0.008
C84.2 T-zone lymphoma	0.000	0.992	0.008
C84.1 Sezary's diease	0.000	0.992	0.008
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.992	0.008
K11.0 Atrophy of salivary gland	0.000	0.992	0.008
T40.1 Heroin	0.008	0.992	0.000
M07 Psoriatic and enteropathic arthropathies	0.008	0.992	0.000
C83.5 Lymphoblastic (diffuse)	0.000	0.992	0.008
T43.9 Psychotropic drug, unspecified	0.008	0.992	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.008	0.992	0.000
T50.8 Diagnostic agents	0.008	0.992	0.000
Y43.3 Other antineoplastic drugs	0.000	0.992	0.008
D50.1 Sideropenic dysphagia	0.000	0.992	0.008
D60.9 Acquired pure red cell aplasia, unspecified	0.000	0.992	0.008
T50.7 Analeptics and opioid receptor antagonists	0.008	0.992	0.000
T50.5 Appetite depressants	0.008	0.992	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.008	0.992	0.000
T50.0 Mineralocorticoids and their antagonists	0.008	0.992	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.008	0.992	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.992	0.008
K11.4 Fistula of salivary gland	0.000	0.992	0.008
T50.1 Loop [high-ceiling] diuretics	0.008	0.992	0.000
T38.9 Other and unspecified hormone antagonists	0.007	0.992	0.000
T38.7 Androgens and anabolic congeners	0.007	0.992	0.000
T38.4 Oral contraceptives	0.007	0.992	0.000
T38.2 Antithyroid drugs	0.007	0.992	0.000
C81 Hodgkin's disease	0.000	0.992	0.008
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.008	0.992	0.000
T42.1 Iminostilbenes	0.008	0.992	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.000	0.992	0.007
C83.7 Burkitt's tumour	0.000	0.992	0.007
C83.6 Undifferentiated (diffuse)	0.000	0.992	0.007
C83.4 Immunoblastic (diffuse)	0.000	0.992	0.007
C83.2 Mixed small and large cell (diffuse)	0.000	0.992	0.007
D52.9 Folate deficiency anaemia, unspecified	0.000	0.992	0.007
T38.0 Glucocorticoids and synthetic analogues	0.007	0.992	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.007	0.992	0.000
C83.3 Large cell (diffuse)	0.000	0.993	0.007
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.000	0.993	0.007
C86.4 Blastic NK-cell lymphoma	0.000	0.993	0.007
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.000	0.993	0.007
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.000	0.993	0.007
C86.1 Hepatosplenic T-cell lymphoma	0.000	0.993	0.007
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.000	0.993	0.007
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.007	0.993	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.007	0.993	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.007	0.993	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.007	0.993	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.007	0.993	0.000
T44.0 Anticholinesterase agents	0.007	0.993	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.000	0.993	0.007
D62 Acute posthaemorrhagic anaemia	0.000	0.993	0.007
T46.1 Calcium-channel blockers	0.007	0.993	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.007	0.993	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.007	0.993	0.000
C95 Leukaemia of unspecified cell type	0.000	0.993	0.007
M07.34 Other psoriatic arthropathies (Hand)	0.007	0.993	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.007	0.993	0.000
C94.4 Acute panmyelosis	0.000	0.993	0.007
D64 Other anaemias	0.000	0.993	0.007
K11.6 Mucocele of salivary gland	0.000	0.993	0.007
T50.4 Drugs affecting uric acid metabolism	0.007	0.993	0.000
T45.2 Vitamins, not elsewhere classified	0.007	0.993	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.993	0.007
T36.4 Tetracyclines	0.007	0.993	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.007	0.993	0.000
T42.3 Barbiturates	0.007	0.993	0.000
I74 Arterial embolism and thrombosis	0.000	0.993	0.007
T42.0 Hydantoin derivatives	0.007	0.993	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.007	0.993	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.007	0.993	0.000
T46.7 Peripheral vasodilators	0.007	0.993	0.000
C94.7 Other specified leukaemias	0.000	0.993	0.007
C94.5 Acute myelofibrosis	0.000	0.993	0.007
C94.3 Mast cell leukaemia	0.000	0.993	0.007
C94.2 Acute megakaryoblastic leukaemia	0.000	0.993	0.007
C94.1 Chronic erythraemia	0.000	0.993	0.007
C94.0 Acute erythraemia and erythroleukaemia	0.000	0.993	0.007
K26.4 Chronic or unspecified with haemorrhage	0.000	0.993	0.007
T39.0 Salicylates	0.007	0.993	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.007	0.993	0.000
T36.8 Other systemic antibiotics	0.007	0.993	0.000
H91.9 Hearing loss, unspecified	0.000	0.993	0.007
M07.39 Other psoriatic arthropathies (Site unspecified)	0.007	0.993	0.000
K11.2 Sialoadenitis	0.000	0.993	0.007
M14 Arthropathies in other diseases classified elsewhere	0.007	0.993	0.000
T36.0 Penicillins	0.007	0.993	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.007	0.993	0.000
K26 Duodenal ulcer	0.000	0.993	0.007
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.007	0.993	0.000
T36.9 Systemic antibiotic, unspecified	0.007	0.993	0.000
T36.7 Antifungal antibiotics, systemically used	0.007	0.993	0.000
T36.6 Rifamycins	0.007	0.993	0.000
T36.5 Aminoglycosides	0.007	0.993	0.000
T36.2 Chloramphenicol group	0.007	0.993	0.000
D83 Common variable immunodeficiency	0.001	0.993	0.006
T36.3 Macrolides	0.007	0.993	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.007	0.993	0.000
D61 Other aplastic anaemias	0.000	0.993	0.007
K26.7 Chronic without haemorrhage or perforation	0.000	0.993	0.007
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.993	0.006
C96.8 Histiocytic sarcoma	0.000	0.993	0.006
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.993	0.006
C96.6 Unifocal Langerhans-cell histiocytosis	0.000	0.993	0.006
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.000	0.993	0.006
C96.4 Sarcoma of dendritic cells (accessory cells)	0.000	0.993	0.006
C96.3 True histiocytic lymphoma	0.000	0.993	0.006
C96.2 Malignant mast cell tumour	0.000	0.993	0.006
C96.1 Malignant histiocytosis	0.000	0.993	0.006
C96.0 Letterer-Siwe disease	0.000	0.993	0.006
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.006	0.993	0.000
T49.9 Topical agent, unspecified	0.006	0.993	0.000
T49.8 Other topical agents	0.006	0.993	0.000
T49.7 Dental drugs, topically applied	0.006	0.993	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.006	0.993	0.000
T49.5 Ophthalmological drugs and preparations	0.006	0.993	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.006	0.993	0.000
T49.3 Emollients, demulcents and protectants	0.006	0.993	0.000
T49.2 Local astringents and local detergents	0.006	0.993	0.000
T49.1 Antipruritics	0.006	0.993	0.000
Z43.2 Attention to ileostomy	0.000	0.993	0.007
T43.4 Butyrophenone and thioxanthene neuroleptics	0.006	0.993	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.006	0.993	0.000
T42.2 Succinimides and oxazolidinediones	0.006	0.993	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.006	0.993	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.006	0.994	0.000
M08 Juvenile arthritis	0.006	0.994	0.000
T41.5 Therapeutic gases	0.006	0.994	0.000
T41.4 Anaesthetic, unspecified	0.006	0.994	0.000
T41.3 Local anaesthetics	0.006	0.994	0.000
T41.2 Other and unspecified general anaesthetics	0.006	0.994	0.000
T41.1 Intravenous anaesthetics	0.006	0.994	0.000
T41.0 Inhaled anaesthetics	0.006	0.994	0.000
T47.0 Histamine H(2)-receptor antagonists	0.006	0.994	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.006	0.994	0.000
T37.5 Antiviral drugs	0.006	0.994	0.000
T37.4 Anthelminthics	0.006	0.994	0.000
T37.3 Other antiprotozoal drugs	0.006	0.994	0.000
T37.1 Antimycobacterial drugs	0.006	0.994	0.000
T37.0 Sulphonamides	0.006	0.994	0.000
T39.4 Antirheumatics, not elsewhere classified	0.006	0.994	0.000
T39.2 Pyrazolone derivatives	0.006	0.994	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.006	0.994	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.006	0.994	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.006	0.994	0.000
T47.7 Emetics	0.006	0.994	0.000
T47.5 Digestants	0.006	0.994	0.000
T47.3 Saline and osmotic laxatives	0.006	0.994	0.000
T47.2 Stimulant laxatives	0.006	0.994	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.006	0.994	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.006	0.994	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.006	0.994	0.000
T47.4 Other laxatives	0.006	0.994	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.006	0.994	0.000
C81.7 Other Hodgkin's disease	0.000	0.994	0.006
C93.9 Monocytic leukaemia, unspecified	0.000	0.994	0.006
C93.7 Other monocytic leukaemia	0.000	0.994	0.006
C93.3 Juvenile myelomonocytic leukaemia	0.000	0.994	0.006
C93.2 Subacute monocytic leukaemia	0.000	0.994	0.006
C93.0 Acute monocytic leukaemia	0.000	0.994	0.006
C88.9 Malignant immunoproliferative disease, unspecified	0.000	0.994	0.006
C88.7 Other malignant immunoproliferative diseases	0.000	0.994	0.006
C88.3 Immunoproliferative small intestinal disease	0.000	0.994	0.006
C88.2 Gamma heavy chain disease	0.000	0.994	0.006
C88.1 Alpha heavy chain disease	0.000	0.994	0.006
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.994	0.006
D81 Combined immunodeficiencies	0.001	0.994	0.005
T39.1 4-Aminophenol derivatives	0.006	0.994	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.006	0.994	0.000
T47.6 Antidiarrhoeal drugs	0.006	0.994	0.000
M14.6 Neuropathic arthropathy	0.006	0.994	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.000	0.994	0.006
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.006	0.994	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.006	0.994	0.000
T48.4 Expectorants	0.006	0.994	0.000
T48.3 Antitussives	0.006	0.994	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.006	0.994	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.006	0.994	0.000
T48.0 Oxytocic drugs	0.006	0.994	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.006	0.994	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.006	0.994	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.006	0.994	0.000
T45.8 Other primarily systemic and haematological agents	0.006	0.994	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.006	0.994	0.000
T45.6 Fibrinolysis-affecting drugs	0.006	0.994	0.000
T45.3 Enzymes, not elsewhere classified	0.006	0.994	0.000
H91.8 Other specified hearing loss	0.000	0.994	0.006
D64.0 Hereditary sideroblastic anaemia	0.000	0.994	0.006
M07.5 Arthropathy in ulcerative colitis	0.006	0.994	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.006	0.994	0.000
M07.2 Psoriatic spondylitis	0.006	0.994	0.000
M07.1 Arthritis mutilans	0.006	0.994	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.006	0.994	0.000
C92 Myeloid leukaemia	0.000	0.994	0.006
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.994	0.006
D82 Immunodeficiency associated with other major defects	0.001	0.994	0.005
C81.2 Mixed cellularity	0.000	0.994	0.006
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.994	0.006
M07.38 Other psoriatic arthropathies (Other)	0.006	0.994	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.006	0.994	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.006	0.994	0.000
C93.1 Chronic monocytic leukaemia	0.000	0.994	0.006
D83.9 Common variable immunodeficiency, unspecified	0.001	0.994	0.005
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.994	0.006
C81.3 Lymphocytic depletion	0.000	0.994	0.006
M07.31 Other psoriatic arthropathies (Shoulder region)	0.006	0.994	0.000
H91 Other hearing loss	0.000	0.994	0.006
C95.0 Acute leukaemia of unspecified cell type	0.000	0.994	0.005
T48.5 Anti-common-cold drugs	0.005	0.994	0.000
K75.9 Inflammatory liver disease, unspecified	0.000	0.994	0.006

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations