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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs504963
log Bayes Factor = 19.4
Chromosome 19   position 49,208,865  (GRCh37) Explore rs504963 on Ensembl!
Variant rs504963 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K80.1 Calculus of gallbladder with other cholecystitis
0.000 0.000 1.000
K80 Cholelithiasis
0.000 0.000 1.000
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.000 1.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.000 0.000 1.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.000 1.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.001 0.999
K26 Duodenal ulcer
0.000 0.001 0.999
K29 Gastritis and duodenitis
0.000 0.001 0.999
K20-K31 Diseases of oesophagus, stomach and duodenum
0.000 0.001 0.999
I10 Essential (primary) hypertension
0.000 0.002 0.998
K29.8 Duodenitis
0.000 0.002 0.998
K82 Other diseases of gallbladder
0.000 0.003 0.997
Chapter XI Diseases of the digestive system
0.000 0.005 0.995
K82.4 Cholesterolosis of gallbladder
0.000 0.014 0.986
K65-K67 Diseases of peritoneum
0.000 0.020 0.980
K29.0 Acute haemorrhagic gastritis
0.000 0.022 0.978
E78.0 Pure hypercholesterolaemia
0.000 0.027 0.973
K83 Other diseases of biliary tract
0.000 0.036 0.964
K66 Other disorders of peritoneum
0.000 0.046 0.954
K82.8 Other specified diseases of gallbladder
0.000 0.049 0.951
K83.1 Obstruction of bile duct
0.000 0.050 0.950
K66.0 Peritoneal adhesions
0.000 0.074 0.926
K29.4 Chronic atrophic gastritis
0.000 0.088 0.912
K82.9 Disease of gallbladder, unspecified
0.000 0.098 0.902
K29.5 Chronic gastritis, unspecified
0.000 0.099 0.901
K31 Other diseases of stomach and duodenum
0.000 0.103 0.897
K83.0 Cholangitis
0.000 0.105 0.895
K66.8 Other specified disorders of peritoneum
0.000 0.119 0.881
K65 Peritonitis
0.000 0.137 0.863
K31.8 Other specified diseases of stomach and duodenum
0.000 0.139 0.861
K26.4 Chronic or unspecified with haemorrhage
0.000 0.163 0.837
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.185 0.815
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.000 0.198 0.802
K26.1 Acute with perforation
0.000 0.200 0.800
K70-K77 Diseases of liver
0.000 0.221 0.779
K27 Peptic ulcer, site unspecified
0.000 0.223 0.777
K29.2 Alcoholic gastritis
0.000 0.225 0.775
K65.8 Other peritonitis
0.000 0.233 0.767
K26.2 Acute with both haemorrhage and perforation
0.000 0.238 0.762
K26.7 Chronic without haemorrhage or perforation
0.000 0.239 0.761
K31.9 Disease of stomach and duodenum, unspecified
0.000 0.246 0.754
K29.3 Chronic superficial gastritis
0.000 0.255 0.745
K23 Disorders of oesophagus in diseases classified elsewhere
0.000 0.265 0.735
K80.8 Other cholelithiasis
0.000 0.275 0.725
K31.4 Gastric diverticulum
0.000 0.276 0.724
K80.3 Calculus of bile duct with cholangitis
0.000 0.283 0.717
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.283 0.717
K70 Alcoholic liver disease
0.000 0.283 0.717
K29.9 Gastroduodenitis, unspecified
0.000 0.284 0.716
K66.9 Disorder of peritoneum, unspecified
0.000 0.291 0.709
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.297 0.703
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.298 0.702
K70.3 Alcoholic cirrhosis of liver
0.000 0.301 0.699
K83.5 Biliary cyst
0.000 0.308 0.691
K83.9 Disease of biliary tract, unspecified
0.000 0.309 0.691
I83 Varicose veins of lower extremities
0.000 0.317 0.683
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.317 0.683
K31.2 Hourglass stricture and stenosis of stomach
0.000 0.318 0.682
K82.3 Fistula of gallbladder
0.000 0.321 0.679
I80 Phlebitis and thrombophlebitis
0.000 0.328 0.672
K27.7 Chronic without haemorrhage or perforation
0.000 0.330 0.670
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.332 0.668
K73 Chronic hepatitis, not elsewhere classified
0.000 0.338 0.662
I10-I15 Hypertensive diseases
0.000 0.339 0.661
K28 Gastrojejunal ulcer
0.000 0.343 0.657
K26.0 Acute with haemorrhage
0.000 0.344 0.656
K31.3 Pylorospasm, not elsewhere classified
0.000 0.347 0.653
K31.0 Acute dilatation of stomach
0.000 0.355 0.645
K31.1 Adult hypertrophic pyloric stenosis
0.000 0.363 0.637
K65.0 Acute peritonitis
0.000 0.364 0.636
K65.9 Peritonitis, unspecified
0.000 0.366 0.634
K25 Gastric ulcer
0.000 0.374 0.626
K82.2 Perforation of gallbladder
0.000 0.379 0.621
K74 Fibrosis and cirrhosis of liver
0.000 0.386 0.614
K83.2 Perforation of bile duct
0.000 0.394 0.606
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.402 0.598
K82.0 Obstruction of gallbladder
0.000 0.408 0.592
I85 Oesophageal varices
0.000 0.424 0.576
K31.6 Fistula of stomach and duodenum
0.000 0.425 0.575
Chapter IX Diseases of the circulatory system
0.000 0.426 0.574
K25.3 Acute without haemorrhage or perforation
0.000 0.428 0.572
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.434 0.566
K26.3 Acute without haemorrhage or perforation
0.000 0.436 0.564
K83.4 Spasm of sphincter of Oddi
0.000 0.440 0.560
K76 Other diseases of liver
0.000 0.441 0.559
K77 Liver disorders in diseases classified elsewhere
0.000 0.442 0.558
K83.3 Fistula of bile duct
0.000 0.442 0.558
K27.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.443 0.557
K27.5 Chronic or unspecified with perforation
0.000 0.443 0.557
K27.4 Chronic or unspecified with haemorrhage
0.000 0.443 0.557
K27.2 Acute with both haemorrhage and perforation
0.000 0.443 0.557
K27.1 Acute with perforation
0.000 0.443 0.557
K27.0 Acute with haemorrhage
0.000 0.443 0.557
I88 Nonspecific lymphadenitis
0.000 0.449 0.551
K73.9 Chronic hepatitis, unspecified
0.000 0.453 0.547
K23.8 Disorders of oesophagus in other diseases classified elsewhere
0.000 0.455 0.545
K26.5 Chronic or unspecified with perforation
0.000 0.456 0.544
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.460 0.540
K74.0 Hepatic fibrosis
0.000 0.464 0.536
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.472 0.528
K23.1 Megaoesophagus in Chagas' disease
0.000 0.473 0.527
K23.0 Tuberculous oesophagitis
0.000 0.473 0.527
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.476 0.524
K82.1 Hydrops of gallbladder
0.000 0.480 0.520
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.483 0.517
K27.3 Acute without haemorrhage or perforation
0.000 0.483 0.517
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction
0.000 0.486 0.514
K87.1 Disorders of pancreas in diseases classified elsewhere
0.000 0.486 0.514
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere
0.000 0.486 0.514
K31.5 Obstruction of duodenum
0.000 0.491 0.509
I85.9 Oesophageal varices without bleeding
0.000 0.492 0.508
K70.9 Alcoholic liver disease, unspecified
0.000 0.493 0.507
K76.8 Other specified diseases of liver
0.000 0.495 0.505
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.496 0.504
K67.3 Tuberculous peritonitis
0.000 0.496 0.504
K67.2 Syphilitic peritonitis
0.000 0.496 0.504
K67.1 Gonococcal peritonitis
0.000 0.496 0.504
K67.0 Chlamydial peritonitis
0.000 0.496 0.504
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.497 0.503
K29.1 Other acute gastritis
0.000 0.505 0.495
I15 Secondary hypertension
0.000 0.507 0.493
K25.5 Chronic or unspecified with perforation
0.000 0.513 0.487
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.514 0.486
K74.5 Biliary cirrhosis, unspecified
0.000 0.523 0.477
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.525 0.475
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.525 0.475
K85 Acute pancreatitis
0.000 0.526 0.474
I13 Hypertensive heart and renal disease
0.000 0.526 0.474
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.527 0.473
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.527 0.473
K28.7 Chronic without haemorrhage or perforation
0.000 0.529 0.471
K28.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.529 0.471
K28.5 Chronic or unspecified with perforation
0.000 0.529 0.471
K28.4 Chronic or unspecified with haemorrhage
0.000 0.529 0.471
K28.3 Acute without haemorrhage or perforation
0.000 0.529 0.471
K28.2 Acute with both haemorrhage and perforation
0.000 0.529 0.471
K28.1 Acute with perforation
0.000 0.529 0.471
K28.0 Acute with haemorrhage
0.000 0.529 0.471
K50-K52 Noninfective enteritis and colitis
0.000 0.530 0.470
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.537 0.463
K71 Toxic liver disease
0.000 0.539 0.461
K25.2 Acute with both haemorrhage and perforation
0.000 0.551 0.449
K25.1 Acute with perforation
0.000 0.551 0.449
K25.7 Chronic without haemorrhage or perforation
0.000 0.552 0.448
I82 Other venous embolism and thrombosis
0.000 0.553 0.447
K90-K93 Other diseases of the digestive system
0.000 0.555 0.445
K74.6 Other and unspecified cirrhosis of liver
0.000 0.558 0.442
K74.4 Secondary biliary cirrhosis
0.000 0.560 0.440
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.560 0.440
K74.1 Hepatic sclerosis
0.000 0.562 0.438
K25.4 Chronic or unspecified with haemorrhage
0.000 0.565 0.435
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.566 0.434
K70.0 Alcoholic fatty liver
0.000 0.566 0.434
K25.0 Acute with haemorrhage
0.000 0.573 0.427
K50 Crohn's disease [regional enteritis]
0.000 0.574 0.426
K70.4 Alcoholic hepatic failure
0.000 0.576 0.424
I26 Pulmonary embolism
0.000 0.578 0.422
K50.1 Crohn's disease of large intestine
0.000 0.584 0.416
K76.1 Chronic passive congestion of liver
0.000 0.584 0.416
I85.0 Oesophageal varices with bleeding
0.000 0.586 0.414
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.589 0.411
I15.9 Seconday hypertension, unspecified
0.000 0.590 0.410
K70.1 Alcoholic hepatitis
0.000 0.594 0.406
I88.8 Other nonspecific lymphadenitis
0.000 0.597 0.403
K72 Hepatic failure, not elsewhere classified
0.000 0.598 0.402
K76.5 Hepatic veno-occlusive disease
0.000 0.599 0.401
K76.4 Peliosis hepatis
0.000 0.599 0.401
K76.3 Infarction of liver
0.000 0.599 0.401
K76.2 Central haemorrhagic necrosis of liver
0.000 0.599 0.401
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.599 0.400
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.599 0.400
I28 Other diseases of pulmonary vessels
0.000 0.601 0.399
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.605 0.395
I87 Other disorders of veins
0.000 0.607 0.393
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.609 0.391
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.609 0.391
K76.0 Fatty (change of) liver, not elsewhere classified
0.000 0.612 0.388
K80.4 Calculus of bile duct with cholecystitis
0.000 0.615 0.385
I00-I02 Acute rheumatic fever
0.000 0.622 0.378
K76.7 Hepatorenal syndrome
0.000 0.624 0.376
K85.8 Other acute pancreatitis
0.000 0.624 0.376
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.625 0.375
I11 Hypertensive heart disease
0.000 0.626 0.374
I86 Varicose veins of other sites
0.000 0.639 0.361
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.642 0.358
I81 Portal vein thrombosis
0.000 0.644 0.356
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.645 0.355
I15.8 Other secondary hypertension
0.000 0.646 0.354
I15.2 Hypertension secondary to endocrine disorders
0.000 0.646 0.354
I15.1 Hypertension secondary to other renal disorders
0.000 0.653 0.347
I28.8 Other specified diseases of pulmonary vessels
0.000 0.655 0.345
I82.0 Budd-Chiari syndrome
0.000 0.658 0.342
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.658 0.342
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.659 0.340
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.660 0.340
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.660 0.340
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.660 0.340
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.660 0.340
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.664 0.336
K71.0 Toxic liver disease with cholestasis
0.000 0.664 0.335
K76.6 Portal hypertension
0.000 0.667 0.333
K71.9 Toxic liver disease, unspecified
0.000 0.669 0.331
K71.8 Toxic liver disease with other disorders of liver
0.000 0.669 0.331
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.669 0.331
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.669 0.331
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.669 0.331
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.669 0.331
K71.2 Toxic liver disease with acute hepatitis
0.000 0.669 0.331
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.671 0.329
I82.2 Embolism and thrombosis of vena cava
0.000 0.672 0.328
K85.1 Biliary acute pancreatitis
0.000 0.676 0.323
I82.1 Thrombophlebitis migrans
0.000 0.680 0.320
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.681 0.319
K85.9 Acute pancreatitis, unspecified
0.000 0.684 0.316
K85.3 Drug-induced acute pancreatitis
0.000 0.686 0.314
K29.6 Other gastritis
0.000 0.692 0.308
K85.0 Idiopathic acute pancreatitis
0.000 0.696 0.303
I15.0 Renovascular hypertension
0.000 0.698 0.301
K83.8 Other specified diseases of biliary tract
0.000 0.699 0.301
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.700 0.300
K91.4 Colostomy and enterostomy malfunction
0.000 0.702 0.298
I82.3 Embolism and thrombosis of renal vein
0.000 0.707 0.293
K50.8 Other Crohn's disease
0.000 0.709 0.291
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.710 0.290
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.710 0.290
I71 Aortic aneurysm and dissection
0.000 0.711 0.289
I72 Other aneurysm
0.000 0.712 0.288
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.713 0.287
I86.4 Gastric varices
0.000 0.713 0.287
I28.1 Aneurysm of pulmonary artery
0.000 0.714 0.286
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.714 0.286
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.715 0.285
K91.1 Postgastric surgery syndromes
0.000 0.716 0.284
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.716 0.284
K91.5 Postcholecystectomy syndrome
0.000 0.717 0.283
I87.0 Postphlebitic syndrome
0.000 0.718 0.282
I12 Hypertensive renal disease
0.000 0.718 0.282
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.718 0.282
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.718 0.281
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.720 0.280
K74.3 Primary biliary cirrhosis
0.000 0.720 0.280
I02 Rheumatic chorea
0.000 0.729 0.271
I01 Rheumatic fever with heart involvement
0.000 0.729 0.271
K72.9 Hepatic failure, unspecified
0.000 0.730 0.270
I60-I69 Cerebrovascular diseases
0.000 0.730 0.270
K76.9 Liver disease, unspecified
0.000 0.732 0.268
I86.8 Varicose veins of other specified sites
0.000 0.732 0.268
K50.9 Crohn's disease, unspecified
0.000 0.737 0.263
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.739 0.261
I70 Atherosclerosis
0.000 0.741 0.259
I86.0 Sublingual varices
0.000 0.741 0.259
I86.2 Pelvic varices
0.000 0.743 0.257
K66.1 Haemoperitoneum
0.003 0.743 0.254
I87.9 Disorder of vein, unspecified
0.000 0.745 0.254
K91.3 Postoperative intestinal obstruction
0.000 0.747 0.253
K72.0 Acute and subacute hepatic failure
0.000 0.748 0.252
I72.4 Aneurysm of artery of lower extremity
0.000 0.751 0.249
I63 Cerebral infarction
0.000 0.751 0.249
K35-K38 Diseases of appendix
0.000 0.751 0.249
I74 Arterial embolism and thrombosis
0.000 0.752 0.248
I61 Intracerebral haemorrhage
0.000 0.755 0.245
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.757 0.243
I86.3 Vulval varices
0.000 0.760 0.239
K40-K46 Hernia
0.000 0.762 0.238
I00 Rheumatic fever without mention of heart involvement
0.000 0.763 0.237
I72.9 Aneurysm of unspecified site
0.000 0.763 0.237
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.765 0.235
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.765 0.235
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.771 0.229
K93.1 Megacolon in Chagas' disease
0.000 0.771 0.229
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.771 0.229
K72.1 Chronic hepatic failure
0.000 0.772 0.227
I70.0 Atherosclerosis of aorta
0.000 0.775 0.225
I72.0 Aneurysm of carotid artery
0.000 0.776 0.224
I72.2 Aneurysm of renal artery
0.000 0.778 0.222
K85.2 Alcohol-induced acute pancreatitis
0.001 0.781 0.218
K75 Other inflammatory liver diseases
0.000 0.784 0.216
K50.0 Crohn's disease of small intestine
0.000 0.784 0.216
I82.8 Embolism and thrombosis of other specified veins
0.000 0.785 0.215
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.788 0.211
I87.1 Compression of vein
0.000 0.789 0.211
I89.1 Lymphangitis
0.000 0.792 0.208
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.793 0.207
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.793 0.207
K41 Femoral hernia
0.000 0.793 0.207
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.793 0.207
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.793 0.207
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.793 0.207
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.793 0.207
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.794 0.206
I60 Subarachnoid haemorrhage
0.000 0.797 0.203
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.798 0.202
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.799 0.201
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.800 0.200
I70.1 Atherosclerosis of renal artery
0.000 0.800 0.200
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.802 0.198
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.803 0.197
I72.8 Aneurysm of other specified arteries
0.000 0.803 0.197
I12.9 Hypertensive renal disease without renal failure
0.000 0.805 0.195
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.805 0.194
I01.8 Other acute rheumatic heart disease
0.000 0.805 0.194
I01.2 Acute rheumatic myocarditis
0.000 0.805 0.194
I01.1 Acute rheumatic endocarditis
0.000 0.805 0.194
I01.0 Acute rheumatic pericarditis
0.000 0.805 0.194
I02.9 Rheumatic chorea without heart involvement
0.000 0.805 0.194
I02.0 Rheumatic chorea with heart involvement
0.000 0.805 0.194
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.808 0.192
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.809 0.191
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.809 0.191
I74.5 Embolism and thrombosis of iliac artery
0.000 0.809 0.191
K75.0 Abscess of liver
0.000 0.809 0.191
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.810 0.190
I72.3 Aneurysm of iliac artery
0.000 0.811 0.189
I70.9 Generalised and unspecified atherosclerosis
0.000 0.814 0.186
I61.8 Other intracerebral haemorrhage
0.000 0.814 0.186
K43 Ventral hernia
0.000 0.815 0.185
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.816 0.184
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.816 0.184
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.816 0.183
I87.8 Other specified disorders of veins
0.000 0.817 0.183
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.819 0.181
I63.9 Cerebral infarction, unspecified
0.000 0.820 0.180
I72.1 Aneurysm of artery of upper extremity
0.000 0.820 0.180
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.821 0.179
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.821 0.179
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.821 0.179
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.823 0.177
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.824 0.176
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.824 0.176
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.824 0.176
K91.2 Postsurgical malabsorption, not elsewhere classified
0.001 0.824 0.175
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.825 0.175
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.825 0.175
K46 Unspecified abdominal hernia
0.000 0.826 0.174
K21 Gastro-oesophageal reflux disease
0.000 0.828 0.172
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.830 0.170
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.831 0.168
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.831 0.168
I98.0 Cardiovascular syphilis
0.000 0.831 0.168
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.832 0.168
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.834 0.166
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.836 0.164
I62 Other nontraumatic intracranial haemorrhage
0.000 0.836 0.164
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.837 0.163
K43.9 Ventral hernia without obstruction or gangrene
0.000 0.838 0.162
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.838 0.161
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.838 0.162
I89.0 Lymphoedema, not elsewhere classified
0.000 0.839 0.161
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.839 0.160
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.840 0.160
I71.0 Dissection of aorta [any part]
0.000 0.840 0.160
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.841 0.159
K36 Other appendicitis
0.000 0.842 0.158
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.843 0.157
I05-I09 Chronic rheumatic heart diseases
0.000 0.844 0.156
I70.8 Atherosclerosis of other arteries
0.000 0.844 0.155
K75.2 Nonspecific reactive hepatitis
0.000 0.845 0.155
K75.1 Phlebitis of portal vein
0.000 0.845 0.155
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.846 0.154
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.849 0.151
I77 Other disorders of arteries and arterioles
0.000 0.850 0.150
I99 Other and unspecified disorders of circulatory system
0.000 0.850 0.150
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.851 0.149
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.851 0.149
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.851 0.149
I65.1 Occlusion and stenosis of basilar artery
0.000 0.852 0.148
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.853 0.147
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.854 0.145
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.856 0.143
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.858 0.142
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.859 0.141
K35 Acute appendicitis
0.000 0.860 0.140
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.860 0.140
K90 Intestinal malabsorption
0.000 0.861 0.139
K52 Other non-infective gastro-enteritis and colitis
0.000 0.862 0.138
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.862 0.138
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.863 0.137
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.863 0.137
I95 Hypotension
0.000 0.863 0.137
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.864 0.136
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.864 0.135
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.866 0.134
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.866 0.133
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.866 0.133
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.867 0.133
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.867 0.133
K43.7 Other and unspecified ventral hernia with gangrene
0.000 0.867 0.132
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.000 0.867 0.132
K43.5 Parastomal hernia without obstruction or gangrene
0.000 0.867 0.132
K43.4 Parastomal hernia with gangrene
0.000 0.867 0.132
K43.3 Parastomal hernia with obstruction, without gangrene
0.000 0.867 0.132
K43.2 Incisional hernia without obstruction or gangrene
0.000 0.867 0.132
K43.1 Ventral hernia with gangrene
0.000 0.867 0.132
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.868 0.132
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.868 0.132
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.868 0.132
K45 Other abdominal hernia
0.000 0.868 0.132
I79.1 Aortitis in diseases classified elsewhere
0.000 0.870 0.130
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.870 0.130
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.870 0.130
I73 Other peripheral vascular diseases
0.000 0.870 0.130
I62.1 Nontraumatic extradural haemorrhage
0.000 0.870 0.129
I69 Sequelae of cerebrovascular disease
0.000 0.871 0.129
I27 Other pulmonary heart diseases
0.000 0.871 0.129
I77.8 Other specified disorders of arteries and arterioles
0.000 0.871 0.129
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.871 0.128
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.871 0.128
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.871 0.128
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.873 0.127
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.873 0.126
K46.1 Unspecified abdominal hernia with gangrene
0.000 0.875 0.125
I60.8 Other subarachnoid haemorrhage
0.000 0.878 0.122
I78 Diseases of capillaries
0.000 0.878 0.122
I68.0 Cerebral amyloid angiopathy
0.000 0.878 0.121
K38 Other diseases of appendix
0.000 0.880 0.120
I63.8 Other cerebral infarction
0.000 0.880 0.120
K35.2 Acute appendicitis with generalized peritonitis
0.000 0.880 0.120
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.880 0.120
I07 Rheumatic tricuspid valve diseases
0.000 0.883 0.117
I11.9 Hypertensive heart disease without (congestive) heart failure
0.001 0.884 0.115
K44 Diaphragmatic hernia
0.000 0.885 0.115
I69.3 Sequelae of cerebral infarction
0.000 0.885 0.115
I77.6 Arteritis, unspecified
0.000 0.886 0.114
I97.0 Postcardiotomy syndrome
0.000 0.886 0.113
I27.9 Pulmonary heart disease, unspecified
0.000 0.887 0.113
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.000 0.887 0.113
I95.2 Hypotension due to drugs
0.000 0.888 0.112
K52.3 Indeterminate colitis
0.000 0.888 0.112
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.888 0.111
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.000 0.888 0.111
K81 Cholecystitis
0.000 0.889 0.111
I95.0 Idiopathic hypotension
0.000 0.890 0.110
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.891 0.109
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.891 0.109
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.891 0.109
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.892 0.108
I77.5 Necrosis of artery
0.000 0.892 0.108
I77.4 Coeliac artery compression syndrome
0.000 0.892 0.108
I06 Rheumatic aortic valve diseases
0.000 0.892 0.107
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.894 0.106
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.894 0.106
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.894 0.106
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.895 0.105
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.896 0.104
K86 Other diseases of pancreas
0.000 0.896 0.104
I77.3 Arterial fibromuscular dysplasia
0.000 0.896 0.104
K35.1 Acute appendicitis with peritoneal abscess
0.000 0.897 0.103
K35.0 Acute appendicitis with generalised peritonitis
0.000 0.897 0.103
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.898 0.102
I09 Other rheumatic heart diseases
0.000 0.898 0.102
N80.0 Endometriosis of uterus
0.000 0.898 0.102
K37 Unspecified appendicitis
0.000 0.899 0.101
K52.1 Toxic gastro-enteritis and colitis
0.000 0.900 0.100
K90.3 Pancreatic steatorrhoea
0.000 0.900 0.100
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.900 0.100
K90.1 Tropical sprue
0.000 0.900 0.100
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.901 0.099
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.901 0.098
K43.0 Ventral hernia with obstruction, without gangrene
0.000 0.902 0.098
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.903 0.097
I97.1 Other functional disturbances following cardiac surgery
0.000 0.903 0.097
K35.8 Acute appendicitis, other and unspecified
0.000 0.903 0.097
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.904 0.096
K90.8 Other intestinal malabsorption
0.000 0.904 0.096
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.904 0.096
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.000 0.905 0.095
I73.8 Other specified peripheral vascular diseases
0.000 0.905 0.095
K45.1 Other specified abdominal hernia with gangrene
0.000 0.905 0.094
K75.4 Autoimmune hepatitis
0.000 0.906 0.093
I74.8 Embolism and thrombosis of other arteries
0.001 0.907 0.093
I27.1 Kyphoscoliotic heart disease
0.000 0.907 0.093
I95.8 Other hypotension
0.000 0.909 0.091
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.912 0.088
I07.1 Tricuspid insufficiency
0.000 0.912 0.088
K38.0 Hyperplasia of appendix
0.000 0.912 0.088
I78.8 Other diseases of capillaries
0.000 0.912 0.087
I77.0 Arteriovenous fistula, acquired
0.000 0.913 0.087
I86.1 Scrotal varices
0.000 0.913 0.086
K38.3 Fistula of appendix
0.000 0.914 0.086
K38.1 Appendicular concretions
0.000 0.915 0.085
I07.9 Tricuspid valve disease, unspecified
0.000 0.916 0.084
I07.8 Other tricuspid valve diseases
0.000 0.916 0.084
I07.2 Tricuspid stenosis with insufficiency
0.000 0.916 0.084
I07.0 Tricuspid stenosis
0.000 0.916 0.084
I78.9 Disease of capillaries, unspecified
0.000 0.916 0.084
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.917 0.083
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.917 0.083
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.918 0.082
I05 Rheumatic mitral valve diseases
0.000 0.918 0.082
I70.80 Atherosclerosis of other arteries (without gangrene)
0.001 0.918 0.081
K35.3 Acute appendicitis with localized peritonitis
0.000 0.919 0.081
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.919 0.081
I95.9 Hypotension, unspecified
0.000 0.920 0.080
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.920 0.080
I06.0 Rheumatic aortic stenosis
0.000 0.920 0.080
I77.2 Rupture of artery
0.000 0.920 0.079
K38.2 Diverticulum of appendix
0.000 0.920 0.079
K38.9 Disease of appendix, unspecified
0.000 0.921 0.079
I06.8 Other rheumatic aortic valve diseases
0.000 0.923 0.077
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.923 0.077

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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