TreeWAS – Variant ID: rs516243

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S42.20 Fracture of upper end of humerus (closed)	0.143	0.857	0.000
S42.2 Fracture of upper end of humerus	0.086	0.914	0.000
S42.21 Fracture of upper end of humerus (open)	0.067	0.933	0.000
S42 Fracture of shoulder and upper arm	0.037	0.963	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.030	0.970	0.000
S42.4 Fracture of lower end of humerus	0.029	0.971	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.026	0.973	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.025	0.974	0.000
S42.1 Fracture of scapula	0.025	0.975	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.025	0.975	0.000
S42.0 Fracture of clavicle	0.023	0.977	0.000
S42.41 Fracture of lower end of humerus (open)	0.023	0.977	0.000
S42.40 Fracture of lower end of humerus (closed)	0.022	0.978	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.022	0.978	0.000
D23.3 Skin of other and unspecified parts of face	0.021	0.979	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.019	0.981	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.019	0.981	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.018	0.981	0.000
S42.3 Fracture of shaft of humerus	0.018	0.981	0.000
S42.11 Fracture of scapula (open)	0.018	0.982	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.017	0.982	0.000
T78.4 Allergy, unspecified	0.000	0.983	0.017
S42.10 Fracture of scapula (closed)	0.017	0.983	0.000
S42.01 Fracture of clavicle (open)	0.017	0.983	0.000
Z52.3 Bone marrow donor	0.016	0.984	0.000
Z52 Donors of organs and tissues	0.015	0.985	0.000
S42.00 Fracture of clavicle (closed)	0.014	0.986	0.000
Z52.4 Kidney donor	0.013	0.987	0.000
S42.31 Fracture of shaft of humerus (open)	0.013	0.987	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.987	0.013
Z52.8 Donor of other organs and tissues	0.013	0.987	0.000
T78 Adverse effects, not elsewhere classified	0.000	0.987	0.013
Z52.0 Blood donor	0.012	0.988	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.988	0.012
T78.3 Angioneurotic oedema	0.000	0.988	0.012
Z52.2 Bone donor	0.012	0.988	0.000
Z52.9 Donor of unspecified organ or tissue	0.011	0.989	0.000
Z52.7 Heart donor	0.011	0.989	0.000
Z52.6 Liver donor	0.011	0.989	0.000
Z52.5 Cornea donor	0.011	0.989	0.000
Z52.1 Skin donor	0.011	0.989	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.990	0.010
S40-S49 Injuries to the shoulder and upper arm	0.010	0.990	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.990	0.010
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.990	0.010
S46 Injury of muscle and tendon at shoulder and upper arm level	0.009	0.991	0.000
T78.8 Other adverse effects, not elsewhere classified	0.000	0.991	0.009
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.991	0.009
T78.9 Adverse effect, unspecified	0.000	0.991	0.009
S46.1 Injury of muscle and tendon of long head of biceps	0.009	0.991	0.000
G83.4 Cauda equina syndrome	0.000	0.991	0.009
I34.1 Mitral (valve) prolapse	0.008	0.992	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.008	0.992	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.992	0.008
M84.0 Malunion of fracture	0.000	0.992	0.008
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.992	0.008
S46.3 Injury of muscle and tendon of triceps	0.008	0.992	0.000
M84.03 Malunion of fracture (Forearm)	0.000	0.992	0.008
M84.06 Malunion of fracture (Lower leg)	0.000	0.992	0.007
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.007	0.992	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.007	0.993	0.000
S48 Traumatic amputation of shoulder and upper arm	0.007	0.993	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.007	0.993	0.000
S44 Injury of nerves at shoulder and upper arm level	0.007	0.993	0.000
S47 Crushing injury of shoulder and upper arm	0.007	0.993	0.000
S41 Open wound of shoulder and upper arm	0.007	0.993	0.000
G83 Other paralytic syndromes	0.000	0.993	0.007
M84 Disorders of continuity of bone	0.000	0.993	0.007
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.993	0.007
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.993	0.007
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.993	0.007
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.007	0.993	0.000
M84.01 Malunion of fracture (Shoulder region)	0.000	0.993	0.007
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.993	0.007
G83.9 Paralytic syndrome, unspecified	0.000	0.993	0.007
S40 Superficial injury of shoulder and upper arm	0.007	0.993	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.993	0.007
G83.1 Monoplegia of lower limb	0.000	0.994	0.006
G83.8 Other specified paralytic syndromes	0.000	0.994	0.006
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.994	0.006
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.994	0.006
M84.04 Malunion of fracture (Hand)	0.000	0.994	0.006
M84.4 Pathological fracture, not elsewhere classified	0.000	0.994	0.006
S02.50 Fracture of tooth (closed)	0.006	0.994	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.994	0.006
M84.09 Malunion of fracture (Site unspecified)	0.000	0.994	0.006
M84.08 Malunion of fracture (Other)	0.000	0.994	0.006
M84.00 Malunion of fracture (Multiple sites)	0.000	0.994	0.006
S42.30 Fracture of shaft of humerus (closed)	0.006	0.994	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.006	0.994	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.994	0.006
S41.0 Open wound of shoulder	0.006	0.994	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.994	0.006
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.994	0.005
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.005	0.994	0.000
S44.8 Injury of other nerves at shoulder and upper arm level	0.005	0.994	0.000
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.005	0.994	0.000
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.005	0.994	0.000
S44.4 Injury of musculocutaneous nerve	0.005	0.994	0.000
S44.3 Injury of axillary nerve	0.005	0.994	0.000
S44.2 Injury of radial nerve at upper arm level	0.005	0.994	0.000
S44.1 Injury of median nerve at upper arm level	0.005	0.994	0.000
S44.0 Injury of ulnar nerve at upper arm level	0.005	0.994	0.000
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.005	0.994	0.000
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.005	0.994	0.000
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.005	0.994	0.000
S45.3 Injury of superficial vein at shoulder and upper arm level	0.005	0.994	0.000
S45.2 Injury of axillary or brachial vein	0.005	0.994	0.000
S45.1 Injury of brachial artery	0.005	0.994	0.000
S45.0 Injury of axillary artery	0.005	0.994	0.000
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.005	0.994	0.000
S48.1 Traumatic amputation at level between shoulder and elbow	0.005	0.994	0.000
S48.0 Traumatic amputation at shoulder joint	0.005	0.994	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.005	0.994	0.000
G83.5 Locked-in syndrome	0.000	0.994	0.005
G83.3 Monoplegia, unspecified	0.000	0.994	0.005
G83.0 Diplegia of upper limbs	0.000	0.994	0.005
M84.9 Disorder of continuity of bone, unspecified	0.000	0.994	0.005
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.005	0.994	0.000
Z93.6 Other artificial openings of urinary tract status	0.000	0.995	0.005
I95.2 Hypotension due to drugs	0.005	0.995	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.995	0.005
G83.2 Monoplegia of upper limb	0.000	0.995	0.005
S41.1 Open wound of upper arm	0.005	0.995	0.000
M84.8 Other disorders of continuity of bone	0.000	0.995	0.005
M31.6 Other giant cell arteritis	0.005	0.995	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.005	0.995	0.000
M84.2 Delayed union of fracture	0.000	0.995	0.005
C48.1 Specified parts of peritoneum	0.005	0.995	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.995	0.005
M84.3 Stress fracture, not elsewhere classified	0.000	0.995	0.005
C48.2 Peritoneum, unspecified	0.005	0.995	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.004	0.995	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.005	0.995	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.995	0.004
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.995	0.004
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.995	0.004
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.995	0.004
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.995	0.004
L81.9 Disorder of pigmentation, unspecified	0.005	0.995	0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.000	0.995	0.005
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.996	0.004
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.000	0.996	0.004
R10.0 Acute abdomen	0.000	0.996	0.004
N02.9 Unspecified	0.004	0.996	0.000
C48.0 Retroperitoneum	0.004	0.996	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.000	0.996	0.004
M84.98 Disorder of continuity of bone, unspecified (Other)	0.000	0.996	0.004
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.000	0.996	0.004
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.000	0.996	0.004
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.000	0.996	0.004
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.000	0.996	0.004
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.000	0.996	0.004
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.000	0.996	0.004
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.000	0.996	0.004
S02.5 Fracture of tooth	0.004	0.996	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.996	0.004
Q60.0 Renal agenesis, unilateral	0.004	0.996	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.004	0.996	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.996	0.004
M84.89 Other disorders of continuity of bone (Site unspecified)	0.000	0.996	0.004
M84.88 Other disorders of continuity of bone (Other)	0.000	0.996	0.004
M84.86 Other disorders of continuity of bone (Lower leg)	0.000	0.996	0.004
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.000	0.996	0.004
M84.84 Other disorders of continuity of bone (Hand)	0.000	0.996	0.004
M84.82 Other disorders of continuity of bone (Upper arm)	0.000	0.996	0.004
M84.81 Other disorders of continuity of bone (Shoulder region)	0.000	0.996	0.004
M84.80 Other disorders of continuity of bone (Multiple sites)	0.000	0.996	0.004
S46.2 Injury of muscle and tendon of other parts of biceps	0.004	0.996	0.000
M84.02 Malunion of fracture (Upper arm)	0.000	0.996	0.003
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.004	0.996	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.000	0.996	0.004
M84.28 Delayed union of fracture (Other)	0.000	0.996	0.004
M84.27 Delayed union of fracture (Ankle and foot)	0.000	0.996	0.004
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.000	0.996	0.004
M84.24 Delayed union of fracture (Hand)	0.000	0.996	0.004
M84.23 Delayed union of fracture (Forearm)	0.000	0.996	0.004
M84.21 Delayed union of fracture (Shoulder region)	0.000	0.996	0.004
M84.20 Delayed union of fracture (Multiple sites)	0.000	0.996	0.004
S40.0 Contusion of shoulder and upper arm	0.004	0.996	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.000	0.996	0.003
M84.38 Stress fracture, not elsewhere classified (Other)	0.000	0.996	0.003
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.000	0.996	0.003
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.996	0.003
M84.34 Stress fracture, not elsewhere classified (Hand)	0.000	0.996	0.003
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.000	0.996	0.003
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.000	0.996	0.003
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.000	0.996	0.003
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.000	0.996	0.003
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.996	0.004
C25.9 Pancreas, unspecified	0.004	0.996	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.004	0.996	0.000
N02.8 Other	0.004	0.996	0.000
N02 Recurrent and persistent haematuria	0.004	0.996	0.000
M84.26 Delayed union of fracture (Lower leg)	0.000	0.996	0.003
J02.9 Acute pharyngitis, unspecified	0.000	0.996	0.004
L05.9 Pilonidal cyst without abscess	0.004	0.996	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.003	0.996	0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.003	0.996	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.996	0.004
M84.22 Delayed union of fracture (Upper arm)	0.000	0.996	0.003
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.004	0.996	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.996	0.004
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.997	0.003
C25.0 Head of pancreas	0.003	0.997	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.997	0.003
K51.2 Ulcerative (chronic) proctitis	0.003	0.997	0.000
S02.51 Fracture of tooth (open)	0.003	0.997	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
K74.3 Primary biliary cirrhosis	0.003	0.997	0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.003	0.997	0.000
E61.1 Iron deficiency	0.003	0.997	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.003	0.997	0.000
O86.4 Pyrexia of unknown origin following delivery	0.000	0.997	0.003
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.003	0.997	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.997	0.003
N02.0 Minor glomerular abnormality	0.003	0.997	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.003	0.997	0.000
N36.2 Urethral caruncle	0.003	0.997	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.997	0.003
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.003	0.997	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.003	0.997	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.003	0.997	0.000
S43.2 Dislocation of sternoclavicular joint	0.003	0.997	0.000
S52.10 Fracture of upper end of radius (closed)	0.003	0.997	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.003	0.997	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.003	0.997	0.000
N02.6 Dense deposit disease	0.003	0.997	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.003	0.997	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.003	0.997	0.000
N02.1 Focal and segmental glomerular lesions	0.003	0.997	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.997	0.003
F01.9 Vascular dementia, unspecified	0.003	0.997	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.003	0.997	0.000
U80.0 Penicillin resistant agent	0.000	0.997	0.003
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.997	0.003
S02 Fracture of skull and facial bones	0.003	0.997	0.000
S02.20 Fracture of nasal bones (closed)	0.003	0.997	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.997	0.003
R09.3 Abnormal sputum	0.003	0.997	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.997	0.003
C25 Malignant neoplasm of pancreas	0.003	0.997	0.000
S02.2 Fracture of nasal bones	0.003	0.997	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.003	0.997	0.000
N02.2 Diffuse membranous glomerulonephritis	0.003	0.997	0.000
S02.1 Fracture of base of skull	0.003	0.997	0.000
S02.7 Multiple fractures involving skull and facial bones	0.003	0.997	0.000
S43.1 Dislocation of acromioclavicular joint	0.002	0.997	0.000
H47.2 Optic atrophy	0.003	0.997	0.000
S43.4 Sprain and strain of shoulder joint	0.002	0.997	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.003	0.997	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.997	0.002
S02.10 Fracture of base of skull (closed)	0.003	0.997	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.002	0.997	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.003	0.997	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.003	0.997	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.002	0.997	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
N05.9 Unspecified	0.002	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.998	0.002
G31.2 Degeneration of nervous system due to alcohol	0.002	0.998	0.000
C25.4 Endocrine pancreas	0.002	0.998	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.002	0.998	0.000
B50.9 Plasmodium falciparum malaria, unspecified	0.002	0.998	0.000
L05.0 Pilonidal cyst with abscess	0.002	0.998	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.002	0.998	0.000
S01.4 Open wound of cheek and temporomandibular area	0.000	0.998	0.002
H73.8 Other specified disorders of tympanic membrane	0.000	0.998	0.002
L05 Pilonidal cyst	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
S02.0 Fracture of vault of skull	0.002	0.998	0.000
S02.8 Fractures of other skull and facial bones	0.002	0.998	0.000
C25.3 Pancreatic duct	0.002	0.998	0.000
F05.9 Delirium, unspecified	0.000	0.998	0.002
S02.11 Fracture of base of skull (open)	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.998	0.002
L81.4 Other melanin hyperpigmentation	0.000	0.998	0.002
T56.8 Other metals	0.000	0.998	0.002
N05 Unspecified nephritic syndrome	0.002	0.998	0.000
H47.5 Disorders of other visual pathways	0.002	0.998	0.000
S02.21 Fracture of nasal bones (open)	0.002	0.998	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.002	0.998	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.000	0.998	0.002
I05.9 Mitral valve disease, unspecified	0.002	0.998	0.000
M31 Other necrotising vasculopathies	0.002	0.998	0.000
C25.8 Overlapping lesion of pancreas	0.002	0.998	0.000
Q60.6 Potter's syndrome	0.002	0.998	0.000
Q60.5 Renal hypoplasia, unspecified	0.002	0.998	0.000
Q60.4 Renal hypoplasia, bilateral	0.002	0.998	0.000
Q60.3 Renal hypoplasia, unilateral	0.002	0.998	0.000
Q60.1 Renal agenesis, bilateral	0.002	0.998	0.000
C25.1 Body of pancreas	0.002	0.998	0.000
H52.1 Myopia	0.002	0.998	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.000	0.998	0.002
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.998	0.002
S49.9 Unspecified injury of shoulder and upper arm	0.002	0.998	0.000
Z56.6 Other physical and mental strain related to work	0.000	0.998	0.002
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.002	0.998	0.000
H47.7 Disorder of visual pathways, unspecified	0.002	0.998	0.000
H47.6 Disorders of visual cortex	0.002	0.998	0.000
H47.4 Disorders of optic chiasm	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.002	0.998	0.000
Z35.5 Supervision of elderly primigravida	0.000	0.998	0.002
C25.7 Other parts of pancreas	0.002	0.998	0.000
E10.5 With peripheral circulatory complications	0.000	0.998	0.002
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.002	0.998	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.998	0.000
S02.3 Fracture of orbital floor	0.002	0.998	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.002	0.998	0.000
K56.7 Ileus, unspecified	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M31.1 Thrombotic microangiopathy	0.002	0.998	0.000
E61 Deficiency of other nutrient elements	0.002	0.998	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.002	0.998	0.000
H04.2 Epiphora	0.000	0.998	0.002
H47.1 Papilloedema, unspecified	0.002	0.998	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.002	0.998	0.000
I34 Nonrheumatic mitral valve disorders	0.002	0.998	0.000
N23 Unspecified renal colic	0.002	0.998	0.000
S02.01 Fracture of vault of skull (open)	0.002	0.998	0.000
S02.00 Fracture of vault of skull (closed)	0.002	0.998	0.000
S02.81 Fractures of other skull and facial bones (open)	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.000	0.998	0.002
S02.80 Fractures of other skull and facial bones (closed)	0.002	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.002	0.998	0.000
Z29.1 Prophylactic immunotherapy	0.002	0.998	0.000
C25.2 Tail of pancreas	0.002	0.998	0.000
K35.8 Acute appendicitis, other and unspecified	0.000	0.998	0.002
N05.6 Dense deposit disease	0.002	0.998	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.998	0.000
N05.0 Minor glomerular abnormality	0.002	0.998	0.000
R09.0 Asphyxia	0.002	0.998	0.000
E53.8 Deficiency of other specified B group vitamins	0.002	0.998	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.002	0.998	0.000
N21.0 Calculus in bladder	0.000	0.998	0.002
I34.2 Nonrheumatic mitral (valve) stenosis	0.002	0.998	0.000
S83.3 Tear of articular cartilage of knee, current	0.000	0.998	0.002
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
M31.2 Lethal midline granuloma	0.002	0.998	0.000
N05.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
G72.9 Myopathy, unspecified	0.000	0.998	0.002
H47.3 Other disorders of optic disk	0.002	0.998	0.000
B50 Plasmodium falciparum malaria	0.002	0.998	0.000
S02.4 Fracture of malar and maxillary bones	0.002	0.998	0.000
N00-N08 Glomerular diseases	0.002	0.998	0.000
C49.3 Connective and soft tissue of thorax	0.002	0.998	0.000
S83.7 Injury to multiple structures of knee	0.000	0.998	0.002
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.998	0.002
Q85.8 Other phakomatoses, not elsewhere classified	0.002	0.998	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.002	0.998	0.000
S02.31 Fracture of orbital floor (open)	0.002	0.998	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.002	0.998	0.000
M31.8 Other specified necrotising vasculopathies	0.002	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
M31.9 Necrotising vasculopathy, unspecified	0.002	0.998	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.002	0.998	0.000
Z49.1 Extracorporeal dialysis	0.002	0.998	0.000
E61.9 Deficiency of nutrient element, unspecified	0.002	0.998	0.000
E61.8 Deficiency of other specified nutrient elements	0.002	0.998	0.000
E61.7 Deficiency of multiple nutrient elements	0.002	0.998	0.000
E61.6 Vanadium deficiency	0.002	0.998	0.000
E61.5 Molybdenum deficiency	0.002	0.998	0.000
E61.4 Chromium deficiency	0.002	0.998	0.000
E61.3 Manganese deficiency	0.002	0.998	0.000
E61.0 Copper deficiency	0.002	0.998	0.000
N36.9 Urethral disorder, unspecified	0.002	0.998	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.002	0.998	0.000
C49.9 Connective and soft tissue, unspecified	0.002	0.998	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.002	0.998	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.001	0.998	0.000
G31.0 Circumscribed brain atrophy	0.002	0.998	0.000
I44.1 Atrioventricular block, second degree	0.000	0.998	0.002
N94.1 Dyspareunia	0.000	0.998	0.002
N26 Unspecified contracted kidney	0.002	0.998	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.998	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.002	0.998	0.000
S02.6 Fracture of mandible	0.001	0.998	0.000
O86 Other puerperal infections	0.000	0.998	0.002
T56 Toxic effect of metals	0.000	0.998	0.002
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.998	0.002
C49.0 Connective and soft tissue of head, face and neck	0.002	0.998	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.001	0.998	0.000
Q50.3 Other congenital malformations of ovary	0.001	0.998	0.000
Q50.2 Congenital torsion of ovary	0.001	0.998	0.000
Q50.1 Developmental ovarian cyst	0.001	0.998	0.000
Q50.0 Congenital absence of ovary	0.001	0.998	0.000
S51.9 Open wound of forearm, part unspecified	0.000	0.998	0.002
T23.2 Burn of second degree of wrist and hand	0.000	0.998	0.002
B59 Pneumocystosis	0.002	0.998	0.000
M31.7 Microscopic polyangiitis	0.001	0.998	0.000
N05.1 Focal and segmental glomerular lesions	0.001	0.998	0.000
T59.8 Other specified gases, fumes and vapours	0.000	0.998	0.002
B50.8 Other severe and complicated Plasmodium falciparum malaria	0.001	0.998	0.000
B50.0 Plasmodium falciparum malaria with cerebral complications	0.001	0.998	0.000
M31.0 Hypersensitivity angiitis	0.001	0.998	0.000
O80.9 Single spontaneous delivery, unspecified	0.002	0.998	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.002	0.998	0.000
R54 Senility	0.002	0.998	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.000	0.998	0.002
E61.2 Magnesium deficiency	0.001	0.998	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.998	0.001
I34.0 Mitral (valve) insufficiency	0.002	0.998	0.000
Q66.7 Pes cavus	0.001	0.998	0.000
Q85.1 Tuberous sclerosis	0.001	0.998	0.000
S83.0 Dislocation of patella	0.000	0.998	0.001
N07 Hereditary nephropathy, not elsewhere classified	0.001	0.998	0.000
N06 Isolated proteinuria with specified morphological lesion	0.001	0.998	0.000
N01 Rapidly progressive nephritic syndrome	0.001	0.998	0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.000	0.998	0.002
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.998	0.001
Q66 Congenital deformities of feet	0.001	0.998	0.000
R68.8 Other specified general symptoms and signs	0.002	0.998	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.998	0.001
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.998	0.001
Q64 Other congenital malformations of urinary system	0.001	0.998	0.000
O72.0 Third-stage haemorrhage	0.000	0.998	0.001
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
J93.9 Pneumothorax, unspecified	0.001	0.999	0.000
M31.3 Wegener's granulomatosis	0.001	0.999	0.000
S52.1 Fracture of upper end of radius	0.001	0.999	0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.001	0.999	0.000
C46 Kaposi's sarcoma	0.001	0.999	0.000
Q63 Other congenital malformations of kidney	0.001	0.999	0.000
O86.2 Urinary tract infection following delivery	0.000	0.999	0.001
Q63.9 Congenital malformation of kidney, unspecified	0.001	0.999	0.000
S80.0 Contusion of knee	0.001	0.999	0.000
E53 Deficiency of other B group vitamins	0.001	0.999	0.000
G62.8 Other specified polyneuropathies	0.001	0.999	0.000
Q12.0 Congenital cataract	0.001	0.999	0.000
S83.1 Dislocation of knee	0.000	0.999	0.001
Z37.2 Twins, both liveborn	0.001	0.999	0.000
N36 Other disorders of urethra	0.001	0.999	0.000
S02.61 Fracture of mandible (open)	0.001	0.999	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.001	0.999	0.000
T56.9 Metal, unspecified	0.000	0.999	0.001
T56.7 Beryllium and its compounds	0.000	0.999	0.001
T56.6 Tin and its compounds	0.000	0.999	0.001
T56.5 Zinc and its compounds	0.000	0.999	0.001
T56.4 Copper and its compounds	0.000	0.999	0.001
T56.3 Cadmium and its compounds	0.000	0.999	0.001
T56.2 Chromium and its compounds	0.000	0.999	0.001
T56.1 Mercury and its compounds	0.000	0.999	0.001
T56.0 Lead and its compounds	0.000	0.999	0.001
Z35.8 Supervision of other high-risk pregnancies	0.000	0.999	0.001
N00 Acute nephritic syndrome	0.001	0.999	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.001	0.999	0.000
Q60-Q64 Congenital malformations of the urinary system	0.001	0.999	0.000
O86.3 Other genito-urinary tract infections following delivery	0.000	0.999	0.001
O86.1 Other infection of genital tract following delivery	0.000	0.999	0.001
Q66.2 Metatarsus varus	0.001	0.999	0.000
T79.7 Traumatic subcutaneous emphysema	0.001	0.999	0.000
S02.30 Fracture of orbital floor (closed)	0.001	0.999	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.001	0.999	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.001	0.999	0.000
Q63.8 Other specified congenital malformations of kidney	0.001	0.999	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.001	0.999	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.999	0.001
N04 Nephrotic syndrome	0.001	0.999	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.001	0.999	0.000
N01.9 Unspecified	0.001	0.999	0.000
N01.8 Other	0.001	0.999	0.000
N01.7 Diffuse crescentic glomerulonephritis	0.001	0.999	0.000
N01.6 Dense deposit disease	0.001	0.999	0.000
N01.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.999	0.000
N01.4 Diffuse endocapillary proliferative glomerulonephritis	0.001	0.999	0.000
N01.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.999	0.000
N01.2 Diffuse membranous glomerulonephritis	0.001	0.999	0.000
N01.1 Focal and segmental glomerular lesions	0.001	0.999	0.000
N01.0 Minor glomerular abnormality	0.001	0.999	0.000
N05.8 Other	0.001	0.999	0.000
N06.9 Unspecified	0.001	0.999	0.000
N06.8 Other	0.001	0.999	0.000
N06.7 Diffuse crescentic glomerulonephritis	0.001	0.999	0.000
N06.6 Dense deposit disease	0.001	0.999	0.000
N06.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.999	0.000
N06.4 Diffuse endocapillary proliferative glomerulonephritis	0.001	0.999	0.000
N06.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.999	0.000
N06.2 Diffuse membranous glomerulonephritis	0.001	0.999	0.000
N06.1 Focal and segmental glomerular lesions	0.001	0.999	0.000
N06.0 Minor glomerular abnormality	0.001	0.999	0.000
N07.9 Unspecified	0.001	0.999	0.000
N07.8 Other	0.001	0.999	0.000
N07.7 Diffuse crescentic glomerulonephritis	0.001	0.999	0.000
N07.6 Dense deposit disease	0.001	0.999	0.000
N07.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.999	0.000
N07.4 Diffuse endocapillary proliferative glomerulonephritis	0.001	0.999	0.000
N07.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.999	0.000
N07.2 Diffuse membranous glomerulonephritis	0.001	0.999	0.000
N07.1 Focal and segmental glomerular lesions	0.001	0.999	0.000
N07.0 Minor glomerular abnormality	0.001	0.999	0.000
Q63.2 Ectopic kidney	0.001	0.999	0.000
Z22.3 Carrier of other specified bacterial diseases	0.000	0.999	0.001
S52.11 Fracture of upper end of radius (open)	0.001	0.999	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.999	0.001
O86.8 Other specified puerperal infections	0.000	0.999	0.001
Q66.5 Congenital pes planus	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations