TreeWAS – Variant ID: rs516732

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T50.9 Other and unspecified drugs, medicaments and biological substances	0.164	0.836	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.146	0.854	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.129	0.871	0.000
T36 Poisoning by systemic antibiotics	0.119	0.881	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.116	0.884	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.115	0.885	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.111	0.889	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.111	0.889	0.000
T50.4 Drugs affecting uric acid metabolism	0.110	0.890	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.109	0.891	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.105	0.895	0.000
T50.7 Analeptics and opioid receptor antagonists	0.105	0.895	0.000
T50.5 Appetite depressants	0.105	0.895	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.105	0.895	0.000
T50.1 Loop [high-ceiling] diuretics	0.105	0.895	0.000
T50.0 Mineralocorticoids and their antagonists	0.105	0.895	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.105	0.895	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.105	0.895	0.000
T36.0 Penicillins	0.104	0.896	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.103	0.897	0.000
T50.8 Diagnostic agents	0.102	0.898	0.000
T45.5 Anticoagulants	0.101	0.899	0.000
T47.4 Other laxatives	0.098	0.902	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.097	0.903	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.096	0.904	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.096	0.904	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.095	0.905	0.000
T36.3 Macrolides	0.095	0.905	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.094	0.906	0.000
T45.4 Iron and its compounds	0.093	0.907	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.092	0.907	0.000
T47.6 Antidiarrhoeal drugs	0.090	0.910	0.000
T36.8 Other systemic antibiotics	0.090	0.910	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.089	0.910	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.086	0.914	0.000
T47.2 Stimulant laxatives	0.086	0.914	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.086	0.914	0.000
T36.9 Systemic antibiotic, unspecified	0.086	0.914	0.000
T36.7 Antifungal antibiotics, systemically used	0.086	0.914	0.000
T36.6 Rifamycins	0.086	0.914	0.000
T36.5 Aminoglycosides	0.086	0.914	0.000
T36.4 Tetracyclines	0.086	0.914	0.000
T36.2 Chloramphenicol group	0.086	0.914	0.000
T45.0 Antiallergic and antiemetic drugs	0.085	0.915	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.085	0.915	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.084	0.916	0.000
T45.2 Vitamins, not elsewhere classified	0.084	0.916	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.083	0.917	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.083	0.917	0.000
T47.7 Emetics	0.083	0.917	0.000
T47.5 Digestants	0.083	0.917	0.000
T47.3 Saline and osmotic laxatives	0.083	0.917	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.083	0.917	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.083	0.917	0.000
T45.8 Other primarily systemic and haematological agents	0.083	0.917	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.083	0.917	0.000
T45.6 Fibrinolysis-affecting drugs	0.083	0.917	0.000
T45.3 Enzymes, not elsewhere classified	0.083	0.917	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.081	0.919	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.080	0.920	0.000
O16 Unspecified maternal hypertension	0.080	0.920	0.000
T47.0 Histamine H(2)-receptor antagonists	0.079	0.921	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.079	0.921	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.078	0.922	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.078	0.922	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.078	0.922	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.078	0.922	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.078	0.922	0.000
T44.0 Anticholinesterase agents	0.078	0.922	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.078	0.922	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.076	0.924	0.000
T39.4 Antirheumatics, not elsewhere classified	0.075	0.924	0.000
T39.2 Pyrazolone derivatives	0.075	0.924	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.075	0.924	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.075	0.924	0.000
T46.7 Peripheral vasodilators	0.075	0.924	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.075	0.925	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.075	0.925	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.075	0.925	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.074	0.926	0.000
T37.5 Antiviral drugs	0.074	0.926	0.000
T37.4 Anthelminthics	0.074	0.926	0.000
T37.3 Other antiprotozoal drugs	0.074	0.926	0.000
T37.1 Antimycobacterial drugs	0.074	0.926	0.000
T37.0 Sulphonamides	0.074	0.926	0.000
T46.1 Calcium-channel blockers	0.072	0.928	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.071	0.929	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.069	0.930	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.069	0.931	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.069	0.931	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.068	0.932	0.000
T41.5 Therapeutic gases	0.066	0.933	0.000
T41.4 Anaesthetic, unspecified	0.066	0.933	0.000
T41.3 Local anaesthetics	0.066	0.933	0.000
T41.2 Other and unspecified general anaesthetics	0.066	0.933	0.000
T41.1 Intravenous anaesthetics	0.066	0.933	0.000
T41.0 Inhaled anaesthetics	0.066	0.933	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.064	0.936	0.000
T49.9 Topical agent, unspecified	0.064	0.936	0.000
T49.8 Other topical agents	0.064	0.936	0.000
T49.7 Dental drugs, topically applied	0.064	0.936	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.064	0.936	0.000
T49.5 Ophthalmological drugs and preparations	0.064	0.936	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.064	0.936	0.000
T49.3 Emollients, demulcents and protectants	0.064	0.936	0.000
T49.2 Local astringents and local detergents	0.064	0.936	0.000
T49.1 Antipruritics	0.064	0.936	0.000
T48.5 Anti-common-cold drugs	0.063	0.937	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.061	0.938	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.061	0.939	0.000
T48.4 Expectorants	0.061	0.939	0.000
T48.3 Antitussives	0.061	0.939	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.061	0.939	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.061	0.939	0.000
T48.0 Oxytocic drugs	0.061	0.939	0.000
T40.4 Other synthetic narcotics	0.060	0.940	0.000
T38.9 Other and unspecified hormone antagonists	0.059	0.940	0.000
T38.7 Androgens and anabolic congeners	0.059	0.940	0.000
T38.5 Other oestrogens and progestogens	0.059	0.940	0.000
T38.4 Oral contraceptives	0.059	0.940	0.000
T38.2 Antithyroid drugs	0.059	0.940	0.000
T38.0 Glucocorticoids and synthetic analogues	0.059	0.940	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.059	0.941	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.057	0.943	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.057	0.943	0.000
O15 Eclampsia	0.056	0.943	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.056	0.944	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.056	0.944	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.056	0.944	0.000
T38.1 Thyroid hormones and substitutes	0.053	0.946	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.050	0.950	0.000
T40.8 Lysergide [LSD]	0.050	0.950	0.000
T40.7 Cannabis (derivatives)	0.050	0.950	0.000
T40.3 Methadone	0.050	0.950	0.000
T40.0 Opium	0.050	0.950	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.050	0.950	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.050	0.950	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.050	0.950	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.050	0.950	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.049	0.951	0.000
T40.5 Cocaine	0.049	0.951	0.000
T40.6 Other and unspecified narcotics	0.045	0.955	0.000
O14.9 Preeclampsia, unspecified	0.045	0.955	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.044	0.956	0.000
T40.1 Heroin	0.043	0.956	0.000
O15.9 Eclampsia, unspecified as to time period	0.041	0.959	0.000
O15.1 Eclampsia in labour	0.041	0.959	0.000
O15.0 Eclampsia in pregnancy	0.041	0.959	0.000
O14.2 HELLP syndrome	0.040	0.960	0.000
O14.1 Severe preeclampsia	0.040	0.960	0.000
O15.2 Eclampsia in the puerperium	0.039	0.960	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.039	0.961	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.038	0.962	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.032	0.968	0.000
O14.0 Moderate preeclampsia	0.031	0.969	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.031	0.969	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.030	0.970	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.030	0.970	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.029	0.971	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.028	0.972	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.028	0.972	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.028	0.972	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.027	0.972	0.000
T42.2 Succinimides and oxazolidinediones	0.027	0.972	0.000
T42.0 Hydantoin derivatives	0.027	0.973	0.000
T43.9 Psychotropic drug, unspecified	0.027	0.973	0.000
T42.3 Barbiturates	0.026	0.974	0.000
T39.0 Salicylates	0.023	0.976	0.000
T43.6 Psychostimulants with abuse potential	0.022	0.978	0.000
T39.1 4-Aminophenol derivatives	0.022	0.978	0.000
O12.0 Gestational oedema	0.021	0.978	0.000
T42.1 Iminostilbenes	0.020	0.979	0.000
T43.2 Other and unspecified antidepressants	0.018	0.982	0.000
T42.4 Benzodiazepines	0.017	0.983	0.000
I22 Subsequent myocardial infarction	0.017	0.983	0.000
O12.2 Gestational oedema with proteinuria	0.016	0.983	0.001
T40.2 Other opioids	0.017	0.983	0.000
Z47.8 Other specified orthopaedic follow-up care	0.015	0.985	0.000
O12.1 Gestational proteinuria	0.014	0.985	0.001
I22.8 Subsequent myocardial infarction of other sites	0.013	0.987	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.011	0.989	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.010	0.990	0.000
Y42.7 Androgens and anabolic congeners	0.009	0.991	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.009	0.991	0.000
A63.0 Anogenital (venereal) warts	0.008	0.992	0.000
D32.9 Meninges, unspecified	0.000	0.994	0.006
T43.0 Tricyclic and tetracyclic antidepressants	0.006	0.994	0.000
Z47 Other orthopaedic follow-up care	0.006	0.994	0.000
F60.9 Personality disorder, unspecified	0.006	0.994	0.000
H04.2 Epiphora	0.006	0.994	0.000
S01.8 Open wound of other parts of head	0.006	0.994	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.995	0.005
I22.1 Subsequent myocardial infarction of inferior wall	0.005	0.995	0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.005	0.995	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.005	0.995	0.000
D32.0 Cerebral meninges	0.000	0.995	0.005
D32 Benign neoplasm of meninges	0.000	0.995	0.005
I46.9 Cardiac arrest, unspecified	0.000	0.995	0.005
O75.8 Other specified complications of labour and delivery	0.005	0.995	0.000
K29.0 Acute haemorrhagic gastritis	0.005	0.995	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.005	0.995	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.005	0.995	0.000
Z47.9 Orthopaedic follow-up care, unspecified	0.004	0.995	0.000
N82.3 Fistula of vagina to large intestine	0.005	0.995	0.000
K29.4 Chronic atrophic gastritis	0.004	0.996	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.004	0.996	0.000
N85.8 Other specified noninflammatory disorders of uterus	0.000	0.996	0.004
O75 Other complications of labour and delivery, not elsewhere classified	0.004	0.996	0.000
N82 Fistulae involving female genital tract	0.004	0.996	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.996	0.004
N82.4 Other female intestinal-genital tract fistulae	0.004	0.996	0.000
O41.0 Oligohydramnios	0.004	0.996	0.000
F60 Specific personality disorders	0.004	0.996	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.004	0.996	0.000
T17.2 Foreign body in pharynx	0.004	0.996	0.000
K29.1 Other acute gastritis	0.004	0.996	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.004	0.996	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
F60.0 Paranoid personality disorder	0.004	0.996	0.000
D32.1 Spinal meninges	0.000	0.996	0.004
O46.9 Antepartum haemorrhage, unspecified	0.004	0.996	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.996	0.004
N82.1 Other female urinary-genital tract fistulae	0.004	0.996	0.000
N82.5 Female genital tract-skin fistulae	0.004	0.996	0.000
N82.8 Other female genital tract fistulae	0.004	0.996	0.000
O41 Other disorders of amniotic fluid and membranes	0.004	0.996	0.000
A63.8 Other specified predominantly sexually transmitted diseases	0.003	0.996	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.996	0.004
O75.0 Maternal distress during labour and delivery	0.004	0.996	0.000
F60.2 Dissocial personality disorder	0.003	0.996	0.000
Y42.2 Antithyroid drugs	0.003	0.996	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.003	0.996	0.000
O75.3 Other infection during labour	0.003	0.997	0.000
M31.6 Other giant cell arteritis	0.000	0.997	0.003
O75.2 Pyrexia during labour, not elsewhere classified	0.003	0.997	0.000
N82.9 Female genital tract fistula, unspecified	0.003	0.997	0.000
O75.4 Other complications of obstetric surgery and procedures	0.003	0.997	0.000
O75.1 Shock during or following labour and delivery	0.003	0.997	0.000
F60.6 Anxious [avoidant] personality disorder	0.003	0.997	0.000
N82.2 Fistula of vagina to small intestine	0.003	0.997	0.000
N82.0 Vesicovaginal fistula	0.003	0.997	0.000
O75.9 Complication of labour and delivery, unspecified	0.003	0.997	0.000
O42 Premature rupture of membranes	0.003	0.997	0.000
Y42.1 Thyroid hormones and substitutes	0.003	0.997	0.000
F60.8 Other specific personality disorders	0.003	0.997	0.000
Y46.6 Other and unspecified antiepileptics	0.003	0.997	0.000
Y49.2 Other and unspecified antidepressants	0.003	0.997	0.000
F60.4 Histrionic personality disorder	0.003	0.997	0.000
F60.1 Schizoid personality disorder	0.003	0.997	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.003	0.997	0.000
R07.0 Pain in throat	0.000	0.997	0.003
Y49.5 Other antipsychotics and neuroleptics	0.003	0.997	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.003	0.997	0.000
F60.7 Dependent personality disorder	0.003	0.997	0.000
K29 Gastritis and duodenitis	0.003	0.997	0.000
Y42.4 Oral contraceptives	0.003	0.997	0.000
Z45.1 Adjustment and management of infusion pump	0.003	0.997	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.003	0.997	0.000
K29.5 Chronic gastritis, unspecified	0.003	0.997	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
B91 Sequelae of poliomyelitis	0.000	0.997	0.003
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
O46.8 Other antepartum haemorrhage	0.003	0.997	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.997	0.003
Y42.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.003	0.997	0.000
Y48.4 Anaesthetic, unspecified	0.003	0.997	0.000
Y46.7 Anti-Parkinsonism drugs	0.003	0.997	0.000
Y46.2 Hydantoin derivatives	0.003	0.997	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.003	0.997	0.000
F60.5 Anankastic personality disorder	0.003	0.997	0.000
Y44.2 Anticoagulants	0.003	0.997	0.000
Y44 Agents primarily affecting blood constituents	0.003	0.997	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.997	0.003
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
K61.0 Anal abscess	0.000	0.997	0.003
O41.1 Infection of amniotic sac and membranes	0.003	0.997	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
F05.9 Delirium, unspecified	0.000	0.997	0.003
Y53 Agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
O70.9 Perineal laceration during delivery, unspecified	0.000	0.997	0.003
Y48 Anaesthetics and therapeutic gases	0.003	0.997	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
O42.9 Premature rupture of membranes, unspecified	0.003	0.997	0.000
S93.1 Dislocation of toe(s)	0.000	0.997	0.003
Y49.8 Other psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.003	0.997	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.997	0.000
Y46.8 Antispasticity drugs	0.002	0.997	0.000
Y46.3 Deoxybarbiturates	0.002	0.997	0.000
Y46.1 Oxazolidinediones	0.002	0.997	0.000
Y46.0 Succinimides	0.002	0.997	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.997	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.997	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.997	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.997	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.997	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.997	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.003	0.997	0.000
Y46.5 Valproic acid	0.002	0.997	0.000
Z39.1 Care and examination of lactating mother	0.000	0.997	0.003
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.997	0.002
J11.1 Influenza with other respiratory manifestations, virus not identified	0.002	0.997	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.997	0.003
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.997	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
K29.9 Gastroduodenitis, unspecified	0.002	0.998	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.002	0.998	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.998	0.002
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.002	0.998	0.000
K29.2 Alcoholic gastritis	0.002	0.998	0.000
Z90.6 Acquired absence of other parts of urinary tract	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.998	0.002
M84.1 Nonunion of fracture [pseudarthrosis]	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.002	0.998	0.000
S62.50 Fracture of thumb (closed)	0.000	0.998	0.002
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.998	0.002
Y40 Systemic antibiotics	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
F60.3 Emotionally unstable personality disorder	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000
Y48.0 Inhaled anaesthetics	0.002	0.998	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
F06.7 Mild cognitive disorder	0.000	0.998	0.002
Y46.4 Iminostilbenes	0.002	0.998	0.000
K29.3 Chronic superficial gastritis	0.002	0.998	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.998	0.002
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
F02 Dementia in other diseases classified elsewhere	0.000	0.998	0.002
A50-A64 Infections with a predominantly sexual mode of transmission	0.002	0.998	0.000
J92.9 Pleural plaque without asbestos	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
F05.0 Delirium not superimposed on dementia, so described	0.000	0.998	0.002
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
M24.1 Other articular cartilage disorders	0.002	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
F02.3 Dementia in Parkinson's disease	0.000	0.998	0.002
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.998	0.002
S80.0 Contusion of knee	0.000	0.998	0.002
Y43.4 Immunosuppressive agents	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Y43 Primarily systemic agents	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
C25.0 Head of pancreas	0.002	0.998	0.000
F60-F69 Disorders of adult personality and behaviour	0.002	0.998	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.002	0.998	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.998	0.000
S62.51 Fracture of thumb (open)	0.000	0.998	0.002
S80.9 Superficial injury of lower leg, unspecified	0.000	0.998	0.002
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
B25.9 Cytomegaloviral disease, unspecified	0.002	0.998	0.000
O44.1 Placenta praevia with haemorrhage	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
Y45.4 Antirheumatics	0.002	0.998	0.000
Y48.3 Local anaesthetics	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
M31 Other necrotising vasculopathies	0.000	0.998	0.002
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.002	0.998	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
K10.2 Inflammatory conditions of jaws	0.002	0.998	0.000
A60 Anogenital herpesviral [herpes simplex] infections	0.002	0.998	0.000
F69 Unspecified disorder of adult personality and behaviour	0.002	0.998	0.000
S80 Superficial injury of lower leg	0.000	0.998	0.002
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.002	0.998	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
M50.1 Cervical disk disorder with radiculopathy	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
F61 Mixed and other personality disorders	0.002	0.998	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.000	0.998	0.002
F05.1 Delirium superimposed on dementia	0.000	0.998	0.002
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.000	0.998	0.002
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.998	0.002
Y40.3 Macrolides	0.002	0.998	0.000
Y41.0 Sulphonamides	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.000	0.998	0.002
G93.0 Cerebral cysts	0.000	0.998	0.002
M31.8 Other specified necrotising vasculopathies	0.000	0.998	0.002
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
A60.0 Herpesviral infection of genitalia and urogenital tract	0.002	0.998	0.000
F05.8 Other delirium	0.000	0.998	0.002
M65.9 Synovitis and tenosynovitis, unspecified	0.002	0.998	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
Y41.4 Anthelminthics	0.002	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
M24.14 Other articular cartilage disorders (Hand)	0.002	0.998	0.000
G51.0 Bell's palsy	0.002	0.998	0.000
R59.0 Localised enlarged lymph nodes	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y41.5 Antiviral drugs	0.002	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.000	0.998	0.002
F02.2 Dementia in Huntington's disease	0.000	0.998	0.002
F02.1 Dementia in Creutzfeldt-Jakob disease	0.000	0.998	0.002
S05.8 Other injuries of eye and orbit	0.002	0.998	0.000
Y43.2 Antineoplastic natural products	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.002	0.998	0.000
I46 Cardiac arrest	0.000	0.998	0.002
B94.8 Sequelae of other specified infectious and parasitic diseases	0.000	0.998	0.002
A59 Trichomoniasis	0.002	0.998	0.000
A56 Other sexually transmitted chlamydial diseases	0.002	0.998	0.000
A54 Gonococcal infection	0.002	0.998	0.000
A53 Other and unspecified syphilis	0.002	0.998	0.000
A51 Early syphilis	0.002	0.998	0.000
A50 Congenital syphilis	0.002	0.998	0.000
A64 Unspecified sexually transmitted disease	0.002	0.998	0.000
A58 Granuloma inguinale	0.002	0.998	0.000
A57 Chancroid	0.002	0.998	0.000
A55 Chlamydial lymphogranuloma (venereum)	0.002	0.998	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.002	0.998	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.002	0.998	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.002	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.998	0.002
M24.19 Other articular cartilage disorders (Site unspecified)	0.002	0.998	0.000
M24.18 Other articular cartilage disorders (Other)	0.002	0.998	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations