TreeWAS – Variant ID: rs521977

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
G35 Multiple sclerosis	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
Chapter VI Diseases of the nervous system	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
Chapter I Certain infectious and parasitic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E27.1 Primary adrenocortical insufficiency	1.000	0.000	0.000
G35-G37 Demyelinating diseases of the central nervous system	1.000	0.000	0.000
B37.8 Candidiasis of other sites	1.000	0.000	0.000
B37 Candidiasis	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
B35-B49 Mycoses	1.000	0.000	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	1.000	0.000	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.001	0.999
E20-E35 Disorders of other endocrine glands	0.999	0.001	0.000
E27 Other disorders of adrenal gland	0.999	0.001	0.000
D69 Purpura and other haemorrhagic conditions	0.999	0.001	0.000
D80-D89 Certain disorders involving the immune mechanism	0.998	0.002	0.000
D69.6 Thrombocytopenia, unspecified	0.995	0.005	0.000
L40-L45 Papulosquamous disorders	0.994	0.006	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.007	0.993
D86 Sarcoidosis	0.993	0.007	0.000
K90 Intestinal malabsorption	0.993	0.007	0.000
M06 Other rheumatoid arthritis	0.000	0.007	0.993
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.992	0.008	0.000
L40 Psoriasis	0.991	0.009	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.990	0.010	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.011	0.989
B25-B34 Other viral diseases	0.987	0.013	0.000
E50-E64 Other nutritional deficiencies	0.986	0.014	0.000
L40.9 Psoriasis, unspecified	0.985	0.015	0.000
B07 Viral warts	0.984	0.016	0.000
B25 Cytomegaloviral disease	0.983	0.017	0.000
B25.9 Cytomegaloviral disease, unspecified	0.979	0.021	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.021	0.979
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.027	0.973
D86.9 Sarcoidosis, unspecified	0.970	0.030	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.969	0.031	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.032	0.968
M05 Seropositive rheumatoid arthritis	0.002	0.033	0.965
L20-L30 Dermatitis and eczema	0.967	0.033	0.000
L10-L14 Bullous disorders	0.966	0.034	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.038	0.962
M05-M14 Inflammatory polyarthropathies	0.005	0.040	0.955
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.041	0.959
D70 Agranulocytosis	0.958	0.042	0.000
L50-L54 Urticaria and erythema	0.958	0.042	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.048	0.952
B37.9 Candidiasis, unspecified	0.947	0.053	0.000
Chapter VIII Diseases of the ear and mastoid process	0.942	0.058	0.000
M06.3 Rheumatoid nodule	0.000	0.060	0.940
D72 Other disorders of white blood cells	0.940	0.060	0.000
L13 Other bullous disorders	0.937	0.063	0.000
E53 Deficiency of other B group vitamins	0.935	0.065	0.000
L52 Erythema nodosum	0.935	0.065	0.000
D50-D53 Nutritional anaemias	0.932	0.068	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.931	0.069	0.000
H80-H83 Diseases of inner ear	0.928	0.072	0.000
L27 Dermatitis due to substances taken internally	0.928	0.072	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.926	0.074	0.000
L13.0 Dermatitis herpetiformis	0.918	0.082	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.913	0.087	0.000
K90.9 Intestinal malabsorption, unspecified	0.912	0.088	0.000
G40-G47 Episodic and paroxysmal disorders	0.912	0.088	0.000
G37 Other demyelinating diseases of central nervous system	0.907	0.093	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.907	0.093	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.094	0.906
H80 Otosclerosis	0.905	0.095	0.000
E55 Vitamin D deficiency	0.904	0.096	0.000
D55-D59 Haemolytic anaemias	0.902	0.097	0.000
D72.8 Other specified disorders of white blood cells	0.900	0.100	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.897	0.103	0.000
G00 Bacterial meningitis, not elsewhere classified	0.896	0.104	0.000
L21 Seborrhoeic dermatitis	0.893	0.107	0.000
C34 Malignant neoplasm of bronchus and lung	0.891	0.109	0.000
E53.8 Deficiency of other specified B group vitamins	0.891	0.109	0.000
H80.9 Otosclerosis, unspecified	0.889	0.111	0.000
G40 Epilepsy	0.887	0.113	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.886	0.114	0.000
Chapter II Neoplasms	0.885	0.115	0.000
G20-G26 Extrapyramidal and movement disorders	0.884	0.116	0.000
E27.2 Addisonian crisis	0.879	0.121	0.000
D59 Acquired haemolytic anaemia	0.878	0.122	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.124	0.876
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.875	0.125	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.127	0.873
D51 Vitamin B12 deficiency anaemia	0.871	0.129	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.869	0.131	0.000
G30-G32 Other degenerative diseases of the nervous system	0.868	0.132	0.000
H81 Disorders of vestibular function	0.867	0.133	0.000
D86.0 Sarcoidosis of lung	0.865	0.135	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.864	0.136	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.864	0.136	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.861	0.139	0.000
H90-H95 Other disorders of ear	0.858	0.142	0.000
G20 Parkinson's disease	0.857	0.143	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.856	0.144	0.000
E20 Hypoparathyroidism	0.853	0.147	0.000
C34.3 Lower lobe, bronchus or lung	0.852	0.148	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.149	0.851
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.851	0.149	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.850	0.150	0.000
D86.3 Sarcoidosis of skin	0.849	0.151	0.000
L40.5 Arthropathic psoriasis	0.846	0.154	0.000
E55.9 Vitamin D deficiency, unspecified	0.846	0.154	0.000
D80 Immunodeficiency with predominantly antibody defects	0.843	0.157	0.000
D68 Other coagulation defects	0.841	0.159	0.000
C34.1 Upper lobe, bronchus or lung	0.841	0.159	0.000
H90 Conductive and sensorineural hearing loss	0.840	0.160	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.840	0.160	0.000
D60-D64 Aplastic and other anaemias	0.840	0.160	0.000
D66 Hereditary factor VIII deficiency	0.839	0.161	0.000
C34.9 Bronchus or lung, unspecified	0.838	0.162	0.000
D69.8 Other specified haemorrhagic conditions	0.836	0.164	0.000
D69.2 Other nonthrombocytopenic purpura	0.835	0.165	0.000
L23 Allergic contact dermatitis	0.831	0.169	0.000
D69.4 Other primary thrombocytopenia	0.828	0.171	0.000
B01 Varicella [chickenpox]	0.827	0.173	0.000
L40.0 Psoriasis vulgaris	0.826	0.174	0.000
E34 Other endocrine disorders	0.826	0.174	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.823	0.177	0.000
D86.1 Sarcoidosis of lymph nodes	0.821	0.179	0.000
L40.3 Pustulosis palmaris et plantaris	0.821	0.179	0.000
C91 Lymphoid leukaemia	0.819	0.181	0.000
E31 Polyglandular dysfunction	0.819	0.181	0.000
B91 Sequelae of poliomyelitis	0.815	0.185	0.000
B37.2 Candidiasis of skin and nail	0.813	0.187	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.812	0.188	0.000
B00 Herpesviral [herpes simplex] infections	0.806	0.194	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.805	0.195	0.000
H81.0 Meniere's disease	0.804	0.196	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.197	0.803
E70-E90 Metabolic disorders	0.801	0.199	0.000
G00.9 Bacterial meningitis, unspecified	0.799	0.201	0.000
D59.1 Other autoimmune haemolytic anaemias	0.798	0.202	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.798	0.202	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.797	0.203	0.000
G00.1 Pneumococcal meningitis	0.797	0.203	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.796	0.204	0.000
K90-K93 Other diseases of the digestive system	0.794	0.206	0.000
M45 Ankylosing spondylitis	0.001	0.206	0.792
E78.0 Pure hypercholesterolaemia	0.000	0.207	0.793
C90.0 Multiple myeloma	0.792	0.208	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.789	0.211	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.789	0.211	0.000
E51 Thiamine deficiency	0.788	0.212	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.786	0.214	0.000
L44 Other papulosquamous disorders	0.783	0.217	0.000
Chapter XI Diseases of the digestive system	0.782	0.218	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.781	0.219	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.220	0.780
D84 Other immunodeficiencies	0.780	0.220	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.780	0.220	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.776	0.224	0.000
D52 Folate deficiency anaemia	0.776	0.224	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.776	0.224	0.000
C88 Malignant immunoproliferative diseases	0.775	0.225	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.771	0.229	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.771	0.229	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.770	0.230	0.000
D64 Other anaemias	0.770	0.230	0.000
E63 Other nutritional deficiencies	0.770	0.230	0.000
H81.3 Other peripheral vertigo	0.768	0.232	0.000
H90.0 Conductive hearing loss, bilateral	0.766	0.234	0.000
G41 Status epilepticus	0.765	0.235	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.765	0.235	0.000
B37.1 Pulmonary candidiasis	0.762	0.238	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.762	0.238	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.760	0.240	0.000
A30-A49 Other bacterial diseases	0.757	0.243	0.000
C90.2 Plasmacytoma, extramedullary	0.756	0.244	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.245	0.755
M06.4 Inflammatory polyarthropathy	0.000	0.245	0.755
E06 Thyroiditis	0.754	0.246	0.000
L26 Exfoliative dermatitis	0.753	0.247	0.000
L42 Pityriasis rosea	0.753	0.247	0.000
E83 Disorders of mineral metabolism	0.752	0.248	0.000
D76.3 Other histiocytosis syndromes	0.752	0.248	0.000
A80-A89 Viral infections of the central nervous system	0.751	0.249	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.750	0.250	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.250	0.750
B36 Other superficial mycoses	0.749	0.250	0.000
C34.2 Middle lobe, bronchus or lung	0.749	0.251	0.000
E20.9 Hypoparathyroidism, unspecified	0.749	0.251	0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.748	0.252	0.000
D61 Other aplastic anaemias	0.745	0.255	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.256	0.744
C91.1 Chronic lymphocytic leukaemia	0.743	0.257	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.743	0.257	0.000
L40.1 Generalised pustular psoriasis	0.742	0.258	0.000
C51-C58 Malignant neoplasms of female genital organs	0.741	0.259	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.740	0.260	0.000
A63.0 Anogenital (venereal) warts	0.740	0.260	0.000
B25.0 Cytomegaloviral pneumonitis	0.739	0.261	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.738	0.262	0.000
E83.5 Disorders of calcium metabolism	0.734	0.266	0.000
H90.3 Sensorineural hearing loss, bilateral	0.734	0.266	0.000
G00.2 Streptococcal meningitis	0.733	0.267	0.000
G51 Facial nerve disorders	0.731	0.269	0.000
H90.5 Sensorineural hearing loss, unspecified	0.730	0.270	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.730	0.270	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.730	0.270	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.729	0.271	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.729	0.271	0.000
C94 Other leukaemias of specified cell type	0.729	0.271	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.727	0.273	0.000
H81.9 Disorder of vestibular function, unspecified	0.727	0.273	0.000
A41 Other septicaemia	0.725	0.275	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.276	0.724
H93 Other disorders of ear, not elsewhere classified	0.723	0.277	0.000
E73 Lactose intolerance	0.723	0.277	0.000
B94 Sequelae of other and unspecified infectious and parasitic diseases	0.722	0.278	0.000
C92 Myeloid leukaemia	0.722	0.278	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.722	0.278	0.000
E89.0 Postprocedural hypothyroidism	0.722	0.278	0.000
C34.0 Main bronchus	0.721	0.279	0.000
K35-K38 Diseases of appendix	0.721	0.279	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.720	0.280	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.720	0.280	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.720	0.280	0.000
A41.9 Septicaemia, unspecified	0.719	0.281	0.000
E28 Ovarian dysfunction	0.718	0.282	0.000
B44 Aspergillosis	0.718	0.282	0.000
B37.4 Candidiasis of other urogenital sites	0.718	0.282	0.000
L11 Other acantholytic disorders	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.717	0.283	0.000
A75-A79 Rickettsioses	0.717	0.283	0.000
A70-A74 Other diseases caused by chlamydiae	0.717	0.283	0.000
A20-A28 Certain zoonotic bacterial diseases	0.717	0.283	0.000
B37.6 Candidal endocarditis	0.717	0.283	0.000
B37.5 Candidal meningitis	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
B48 Other mycoses, not elsewhere classified	0.717	0.283	0.000
B47 Mycetoma	0.717	0.283	0.000
B46 Zygomycosis	0.717	0.283	0.000
B45 Cryptococcosis	0.717	0.283	0.000
B43 Chromomycosis and phaeomycotic abscess	0.717	0.283	0.000
B42 Sporotrichosis	0.717	0.283	0.000
B41 Paracoccidioidomycosis	0.717	0.283	0.000
B40 Blastomycosis	0.717	0.283	0.000
B39 Histoplasmosis	0.717	0.283	0.000
B38 Coccidioidomycosis	0.717	0.283	0.000
D67 Hereditary factor IX deficiency	0.717	0.283	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.717	0.283	0.000
E27.5 Adrenomedullary hyperfunction	0.716	0.284	0.000
E27.0 Other adrenocortical overactivity	0.716	0.284	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.716	0.284	0.000
E32 Diseases of thymus	0.716	0.284	0.000
E30 Disorders of puberty, not elsewhere classified	0.716	0.284	0.000
E25 Adrenogenital disorders	0.716	0.284	0.000
D81 Combined immunodeficiencies	0.716	0.284	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.715	0.285	0.000
B37.0 Candidal stomatitis	0.713	0.287	0.000
K70-K77 Diseases of liver	0.713	0.287	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.713	0.287	0.000
E53.9 Vitamin B deficiency, unspecified	0.713	0.287	0.000
L41 Parapsoriasis	0.713	0.287	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.713	0.287	0.000
K90.3 Pancreatic steatorrhoea	0.712	0.288	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.712	0.288	0.000
K90.1 Tropical sprue	0.712	0.288	0.000
M06.2 Rheumatoid bursitis	0.000	0.288	0.712
M06.1 Adult-onset Still's disease	0.000	0.288	0.712
B06 Rubella [German measles]	0.712	0.288	0.000
B05 Measles	0.712	0.288	0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.712	0.288	0.000
B04 Monkeypox	0.712	0.288	0.000
B03 Smallpox	0.712	0.288	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.712	0.288	0.000
L40.4 Guttate psoriasis	0.711	0.289	0.000
L40.2 Acrodermatitis continua	0.711	0.289	0.000
D82 Immunodeficiency associated with other major defects	0.710	0.290	0.000
C90.3 Solitary plasmacytoma	0.710	0.290	0.000
D74 Methaemoglobinaemia	0.710	0.290	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.710	0.290	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.710	0.290	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.709	0.291	0.000
B37.7 Candidal septicaemia	0.708	0.292	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.708	0.292	0.000
B33 Other viral diseases, not elsewhere classified	0.708	0.292	0.000
B30 Viral conjunctivitis	0.708	0.292	0.000
B26 Mumps	0.708	0.292	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.707	0.293	0.000
E56 Other vitamin deficiencies	0.707	0.293	0.000
E50 Vitamin A deficiency	0.707	0.293	0.000
E60 Dietary zinc deficiency	0.707	0.293	0.000
E59 Dietary selenium deficiency	0.707	0.293	0.000
E54 Ascorbic acid deficiency	0.707	0.293	0.000
E52 Niacin deficiency [pellagra]	0.707	0.293	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.294	0.706
L12 Pemphigoid	0.706	0.294	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.295	0.705
B25.2 Cytomegaloviral pancreatitis	0.705	0.295	0.000
B25.1 Cytomegaloviral hepatitis	0.705	0.295	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.705	0.295	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.703	0.297	0.000
L20 Atopic dermatitis	0.703	0.297	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.702	0.298	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.298	0.702
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.298	0.702
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.298	0.702
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.298	0.702
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.298	0.702
A65-A69 Other spirochaetal diseases	0.701	0.299	0.000
C83.0 Small cell (diffuse)	0.700	0.300	0.000
D64.9 Anaemia, unspecified	0.698	0.302	0.000
B25.8 Other cytomegaloviral diseases	0.698	0.302	0.000
D72.1 Eosinophilia	0.698	0.302	0.000
K90.8 Other intestinal malabsorption	0.698	0.302	0.000
D69.5 Secondary thrombocytopenia	0.697	0.303	0.000
E05.8 Other thyrotoxicosis	0.693	0.307	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.002	0.307	0.692
M05.2 Rheumatoid vasculitis	0.002	0.307	0.692
M05.1 Rheumatoid lung disease	0.002	0.307	0.692
M05.0 Felty's syndrome	0.002	0.307	0.692
L24 Irritant contact dermatitis	0.693	0.307	0.000
L22 Diaper [napkin] dermatitis	0.693	0.307	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.692	0.308	0.000
L10 Pemphigus	0.692	0.308	0.000
L14 Bullous disorders in diseases classified elsewhere	0.692	0.308	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.692	0.308	0.000
D61.9 Aplastic anaemia, unspecified	0.691	0.309	0.000
E31.0 Autoimmune polyglandular failure	0.690	0.310	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.004	0.311	0.685
M08 Juvenile arthritis	0.004	0.311	0.685
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.312	0.688
G81 Hemiplegia	0.687	0.313	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.313	0.686
L54 Erythema in diseases classified elsewhere	0.687	0.313	0.000
D69.1 Qualitative platelet defects	0.686	0.313	0.000
K75 Other inflammatory liver diseases	0.686	0.314	0.000
E07 Other disorders of thyroid	0.682	0.317	0.001
M05.8 Other seropositive rheumatoid arthritis	0.002	0.319	0.680
D53 Other nutritional anaemias	0.681	0.319	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.681	0.319	0.000
K37 Unspecified appendicitis	0.680	0.320	0.000
E61 Deficiency of other nutrient elements	0.680	0.320	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.679	0.321	0.000
C86 Other specified types of T/NK-cell lymphoma	0.678	0.322	0.000
C31 Malignant neoplasm of accessory sinuses	0.677	0.323	0.000
E34.9 Endocrine disorder, unspecified	0.676	0.324	0.000
G41.0 Grand mal status epilepticus	0.676	0.324	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.326	0.674
M06.38 Rheumatoid nodule (Other)	0.000	0.326	0.674
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.326	0.674
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.326	0.674
M06.33 Rheumatoid nodule (Forearm)	0.000	0.326	0.674
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.326	0.674
D72.9 Disorder of white blood cells, unspecified	0.674	0.326	0.000
D72.0 Genetic anomalies of leukocytes	0.674	0.326	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.673	0.327	0.000
C91.0 Acute lymphoblastic leukaemia	0.673	0.327	0.000
L13.9 Bullous disorder, unspecified	0.672	0.328	0.000
L13.8 Other specified bullous disorders	0.672	0.328	0.000
L13.1 Subcorneal pustular dermatitis	0.672	0.328	0.000
D69.9 Haemorrhagic condition, unspecified	0.671	0.328	0.000
E83.1 Disorders of iron metabolism	0.671	0.329	0.000
G58 Other mononeuropathies	0.671	0.329	0.000
C93 Monocytic leukaemia	0.671	0.329	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.671	0.329	0.000
E58 Dietary calcium deficiency	0.671	0.329	0.000
E53.1 Pyridoxine deficiency	0.670	0.330	0.000
E53.0 Riboflavin deficiency	0.670	0.330	0.000
L53 Other erythematous conditions	0.669	0.331	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.667	0.333	0.000
G23 Other degenerative diseases of basal ganglia	0.667	0.333	0.000
G36 Other acute disseminated demyelination	0.667	0.333	0.000
E73.9 Lactose intolerance, unspecified	0.667	0.333	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.666	0.334	0.000
E88 Other metabolic disorders	0.666	0.334	0.000
L27.9 Dermatitis due to unspecified substance taken internally	0.665	0.335	0.000
L27.8 Dermatitis due to other substances taken internally	0.665	0.335	0.000
L28 Lichen simplex chronicus and prurigo	0.665	0.335	0.000
C85.1 B-cell lymphoma, unspecified	0.665	0.335	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.665	0.335	0.000
B01.9 Varicella without complications	0.664	0.336	0.000
D52.9 Folate deficiency anaemia, unspecified	0.664	0.336	0.000
L50 Urticaria	0.664	0.336	0.000
K38 Other diseases of appendix	0.663	0.337	0.000
M12 Other specific arthropathies	0.003	0.338	0.658
D68.6 Other Thrombophilia	0.661	0.339	0.000
K70 Alcoholic liver disease	0.661	0.339	0.000
C34.8 Overlapping lesion of bronchus and lung	0.660	0.340	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.340	0.660
K75.8 Other specified inflammatory liver diseases	0.659	0.341	0.000
B27 Infectious mononucleosis	0.658	0.342	0.000
B01.2 Varicella pneumonia	0.657	0.343	0.000
B00.4 Herpesviral encephalitis	0.657	0.343	0.000
G31.8 Other specified degenerative diseases of nervous system	0.656	0.344	0.000
D68.9 Coagulation defect, unspecified	0.655	0.345	0.000
D68.0 Von Willebrand's disease	0.655	0.345	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.655	0.345	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.654	0.346	0.000
L51 Erythema multiforme	0.654	0.346	0.000
D89.1 Cryoglobulinaemia	0.654	0.346	0.000
E04 Other non-toxic goitre	0.653	0.347	0.000
C92.0 Acute myeloid leukaemia	0.652	0.348	0.000
A40 Streptococcal septicaemia	0.651	0.349	0.000
C52 Malignant neoplasm of vagina	0.651	0.349	0.000
G37.5 Concentric sclerosis [Balo]	0.651	0.349	0.000
G37.4 Subacute necrotising myelitis	0.651	0.349	0.000
G37.2 Central pontine myelinolysis	0.651	0.349	0.000
G37.1 Central demyelination of corpus callosum	0.651	0.349	0.000
G37.0 Diffuse sclerosis	0.651	0.349	0.000
B90 Sequelae of tuberculosis	0.650	0.350	0.000
B92 Sequelae of leprosy	0.650	0.350	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.350	0.650
C90.1 Plasma cell leukaemia	0.649	0.351	0.000
H80.8 Other otosclerosis	0.649	0.351	0.000
H80.2 Cochlear otosclerosis	0.649	0.351	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.649	0.351	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.649	0.351	0.000
E55.0 Rickets, active	0.648	0.351	0.000
K75.4 Autoimmune hepatitis	0.648	0.352	0.000
D83 Common variable immunodeficiency	0.647	0.353	0.000
D57 Sickle-cell disorders	0.647	0.353	0.000
D55 Anaemia due to enzyme disorders	0.647	0.353	0.000
E51.2 Wernicke's encephalopathy	0.646	0.353	0.000
G46.4 Cerebellar stroke syndrome	0.646	0.353	0.000
D68.5 Primary Thrombophilia	0.646	0.354	0.000
D84.1 Defects in the complement system	0.646	0.354	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.643	0.357	0.000
G00.8 Other bacterial meningitis	0.643	0.357	0.000
G00.3 Staphylococcal meningitis	0.643	0.357	0.000
G00.0 Haemophilus meningitis	0.643	0.357	0.000
D68.2 Hereditary deficiency of other clotting factors	0.643	0.357	0.000
D86.8 Sarcoidosis of other and combined sites	0.643	0.357	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.642	0.358	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.642	0.358	0.000
G21 Secondary Parkinsonism	0.641	0.359	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.640	0.359	0.000
L21.8 Other seborrhoeic dermatitis	0.640	0.360	0.000
L21.1 Seborrhoeic infantile dermatitis	0.640	0.360	0.000
L21.0 Seborrhoea capitis	0.640	0.360	0.000
B65-B83 Helminthiases	0.640	0.360	0.000
G40.5 Special epileptic syndromes	0.640	0.360	0.000
B50-B64 Protozoal diseases	0.640	0.360	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.636	0.364	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.635	0.365	0.000
H93.1 Tinnitus	0.635	0.365	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.634	0.366	0.000
G11 Hereditary ataxia	0.634	0.366	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.634	0.366	0.000
G22 Parkinsonism in diseases classified elsewhere	0.634	0.366	0.000
L44.0 Pityriasis rubra pilaris	0.632	0.368	0.000
A15-A19 Tuberculosis	0.632	0.368	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.632	0.368	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.632	0.368	0.000
L25 Unspecified contact dermatitis	0.630	0.370	0.000
G51.0 Bell's palsy	0.630	0.370	0.000
D59.8 Other acquired haemolytic anaemias	0.629	0.370	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.629	0.370	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.629	0.370	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.629	0.370	0.000
D59.3 Haemolytic-uraemic syndrome	0.629	0.370	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.629	0.370	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.629	0.370	0.000
H81.8 Other disorders of vestibular function	0.629	0.371	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.629	0.371	0.000
D73 Diseases of spleen	0.629	0.371	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.628	0.372	0.000
C91.4 Hairy-cell leukaemia	0.627	0.373	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.627	0.373	0.000
G81.9 Hemiplegia, unspecified	0.627	0.373	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.626	0.374	0.000
K70.9 Alcoholic liver disease, unspecified	0.625	0.375	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.624	0.376	0.000
D51.2 Transcobalamin II deficiency	0.624	0.376	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.624	0.376	0.000
E24 Cushing's syndrome	0.623	0.376	0.000
H81.4 Vertigo of central origin	0.621	0.379	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.621	0.379	0.000
G45.3 Amaurosis fugax	0.621	0.379	0.000
A59 Trichomoniasis	0.620	0.380	0.000
A56 Other sexually transmitted chlamydial diseases	0.620	0.380	0.000
A54 Gonococcal infection	0.620	0.380	0.000
A53 Other and unspecified syphilis	0.620	0.380	0.000
A52 Late syphilis	0.620	0.380	0.000
A51 Early syphilis	0.620	0.380	0.000
A50 Congenital syphilis	0.620	0.380	0.000
A64 Unspecified sexually transmitted disease	0.620	0.380	0.000
A58 Granuloma inguinale	0.620	0.380	0.000
A57 Chancroid	0.620	0.380	0.000
A55 Chlamydial lymphogranuloma (venereum)	0.620	0.380	0.000
C85.0 Lymphosarcoma	0.619	0.381	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.381	0.619
D64.8 Other specified anaemias	0.619	0.381	0.000
E40-E46 Malnutrition	0.618	0.381	0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.618	0.382	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations