TreeWAS – Variant ID: rs535586

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
G35 Multiple sclerosis	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
Chapter VI Diseases of the nervous system	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
G35-G37 Demyelinating diseases of the central nervous system	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter I Certain infectious and parasitic diseases	1.000	0.000	0.000
B37.8 Candidiasis of other sites	1.000	0.000	0.000
B37 Candidiasis	1.000	0.000	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	1.000	0.000	0.000
B35-B49 Mycoses	0.999	0.001	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.998	0.002	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.003	0.997
E27.1 Primary adrenocortical insufficiency	0.997	0.003	0.000
L40-L45 Papulosquamous disorders	0.996	0.004	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.004	0.996
L40 Psoriasis	0.995	0.005	0.000
E20-E35 Disorders of other endocrine glands	0.993	0.007	0.000
E27 Other disorders of adrenal gland	0.993	0.007	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.993	0.007	0.000
D69 Purpura and other haemorrhagic conditions	0.991	0.009	0.000
E50-E64 Other nutritional deficiencies	0.989	0.011	0.000
B07 Viral warts	0.988	0.012	0.000
M06 Other rheumatoid arthritis	0.000	0.015	0.985
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.016	0.984
D70-D77 Other diseases of blood and blood-forming organs	0.984	0.016	0.000
K90 Intestinal malabsorption	0.984	0.016	0.000
L50-L54 Urticaria and erythema	0.981	0.019	0.000
L40.9 Psoriasis, unspecified	0.976	0.024	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.024	0.976
D69.6 Thrombocytopenia, unspecified	0.975	0.025	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.025	0.975
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.029	0.971
E53 Deficiency of other B group vitamins	0.970	0.030	0.000
L40.5 Arthropathic psoriasis	0.969	0.031	0.000
L52 Erythema nodosum	0.968	0.032	0.000
D72 Other disorders of white blood cells	0.965	0.035	0.000
B25-B34 Other viral diseases	0.960	0.040	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.041	0.959
L20-L30 Dermatitis and eczema	0.957	0.043	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.954	0.046	0.000
M05 Seropositive rheumatoid arthritis	0.004	0.046	0.950
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.954	0.046	0.000
E53.8 Deficiency of other specified B group vitamins	0.952	0.048	0.000
D80-D89 Certain disorders involving the immune mechanism	0.951	0.049	0.000
B37.9 Candidiasis, unspecified	0.951	0.049	0.000
B25 Cytomegaloviral disease	0.948	0.052	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.052	0.948
D72.8 Other specified disorders of white blood cells	0.948	0.052	0.000
L10-L14 Bullous disorders	0.945	0.055	0.000
B25.9 Cytomegaloviral disease, unspecified	0.941	0.059	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.941	0.059	0.000
M05-M14 Inflammatory polyarthropathies	0.009	0.060	0.931
L27 Dermatitis due to substances taken internally	0.937	0.063	0.000
G62 Other polyneuropathies	0.934	0.066	0.000
G62.9 Polyneuropathy, unspecified	0.931	0.069	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.930	0.070	0.000
M06.3 Rheumatoid nodule	0.000	0.072	0.928
G00 Bacterial meningitis, not elsewhere classified	0.909	0.091	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.092	0.908
M06.34 Rheumatoid nodule (Hand)	0.000	0.107	0.893
G30-G32 Other degenerative diseases of the nervous system	0.889	0.111	0.000
L13 Other bullous disorders	0.887	0.113	0.000
D86 Sarcoidosis	0.883	0.117	0.000
E78.0 Pure hypercholesterolaemia	0.000	0.119	0.881
E04 Other non-toxic goitre	0.874	0.126	0.000
D70 Agranulocytosis	0.868	0.132	0.000
G37 Other demyelinating diseases of central nervous system	0.866	0.134	0.000
L21 Seborrhoeic dermatitis	0.865	0.135	0.000
B01 Varicella [chickenpox]	0.855	0.145	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.148	0.852
D55-D59 Haemolytic anaemias	0.851	0.149	0.000
K90.9 Intestinal malabsorption, unspecified	0.849	0.151	0.000
D68 Other coagulation defects	0.846	0.154	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.846	0.154	0.000
L13.0 Dermatitis herpetiformis	0.845	0.155	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.158	0.842
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.842	0.158	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.841	0.159	0.000
D69.8 Other specified haemorrhagic conditions	0.836	0.164	0.000
L23 Allergic contact dermatitis	0.835	0.165	0.000
D69.2 Other nonthrombocytopenic purpura	0.834	0.166	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.831	0.169	0.000
B36 Other superficial mycoses	0.830	0.170	0.000
E27.2 Addisonian crisis	0.830	0.170	0.000
D66 Hereditary factor VIII deficiency	0.827	0.173	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.826	0.174	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.823	0.177	0.000
D69.4 Other primary thrombocytopenia	0.823	0.177	0.000
D80 Immunodeficiency with predominantly antibody defects	0.821	0.179	0.000
L40.3 Pustulosis palmaris et plantaris	0.817	0.182	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.817	0.183	0.000
D59 Acquired haemolytic anaemia	0.816	0.184	0.000
B37.1 Pulmonary candidiasis	0.816	0.184	0.000
E31 Polyglandular dysfunction	0.815	0.185	0.000
E55 Vitamin D deficiency	0.815	0.185	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.811	0.189	0.000
L40.1 Generalised pustular psoriasis	0.810	0.190	0.000
G00.9 Bacterial meningitis, unspecified	0.808	0.192	0.000
G20-G26 Extrapyramidal and movement disorders	0.806	0.194	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.199	0.801
E51 Thiamine deficiency	0.801	0.199	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.799	0.201	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.796	0.203	0.000
K90-K93 Other diseases of the digestive system	0.792	0.208	0.000
E04.0 Non-toxic diffuse goitre	0.790	0.210	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.789	0.211	0.000
E04.2 Non-toxic multinodular goitre	0.783	0.217	0.000
E53.9 Vitamin B deficiency, unspecified	0.780	0.220	0.000
Chapter XI Diseases of the digestive system	0.780	0.220	0.000
E20 Hypoparathyroidism	0.779	0.221	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.779	0.221	0.000
G00.1 Pneumococcal meningitis	0.779	0.221	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.778	0.222	0.000
D86.9 Sarcoidosis, unspecified	0.776	0.224	0.000
B37.2 Candidiasis of skin and nail	0.773	0.227	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.228	0.772
G80-G83 Cerebral palsy and other paralytic syndromes	0.772	0.228	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.770	0.230	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.770	0.230	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.231	0.769
L40.0 Psoriasis vulgaris	0.769	0.231	0.000
L44 Other papulosquamous disorders	0.769	0.231	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.768	0.232	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.767	0.233	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.766	0.234	0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.763	0.237	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.762	0.238	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.761	0.239	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.761	0.239	0.000
E24 Cushing's syndrome	0.761	0.239	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.760	0.240	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.760	0.240	0.000
E63 Other nutritional deficiencies	0.758	0.242	0.000
L26 Exfoliative dermatitis	0.755	0.245	0.000
L42 Pityriasis rosea	0.751	0.249	0.000
E34 Other endocrine disorders	0.749	0.251	0.000
B37.4 Candidiasis of other urogenital sites	0.748	0.252	0.000
G00.2 Streptococcal meningitis	0.747	0.253	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.746	0.253	0.000
G20 Parkinson's disease	0.745	0.255	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.256	0.744
B37.0 Candidal stomatitis	0.743	0.257	0.000
D72.1 Eosinophilia	0.741	0.259	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.260	0.739
L12 Pemphigoid	0.739	0.261	0.000
D76.3 Other histiocytosis syndromes	0.738	0.262	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.262	0.737
L51 Erythema multiforme	0.737	0.263	0.000
D86.1 Sarcoidosis of lymph nodes	0.736	0.264	0.000
D59.1 Other autoimmune haemolytic anaemias	0.734	0.266	0.000
D69.5 Secondary thrombocytopenia	0.734	0.266	0.000
D86.3 Sarcoidosis of skin	0.733	0.267	0.000
G62.1 Alcoholic polyneuropathy	0.732	0.268	0.000
E70-E90 Metabolic disorders	0.729	0.271	0.000
Chapter VIII Diseases of the ear and mastoid process	0.726	0.274	0.000
G64 Other disorders of peripheral nervous system	0.718	0.281	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
G36 Other acute disseminated demyelination	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.717	0.283	0.000
A75-A79 Rickettsioses	0.717	0.283	0.000
A70-A74 Other diseases caused by chlamydiae	0.717	0.283	0.000
A20-A28 Certain zoonotic bacterial diseases	0.717	0.283	0.000
B37.6 Candidal endocarditis	0.717	0.283	0.000
B37.5 Candidal meningitis	0.717	0.283	0.000
B48 Other mycoses, not elsewhere classified	0.717	0.283	0.000
B47 Mycetoma	0.717	0.283	0.000
B46 Zygomycosis	0.717	0.283	0.000
B45 Cryptococcosis	0.717	0.283	0.000
B43 Chromomycosis and phaeomycotic abscess	0.717	0.283	0.000
B42 Sporotrichosis	0.717	0.283	0.000
B41 Paracoccidioidomycosis	0.717	0.283	0.000
B40 Blastomycosis	0.717	0.283	0.000
B39 Histoplasmosis	0.717	0.283	0.000
B38 Coccidioidomycosis	0.717	0.283	0.000
L50 Urticaria	0.716	0.283	0.000
B01.9 Varicella without complications	0.716	0.284	0.000
D67 Hereditary factor IX deficiency	0.715	0.284	0.000
K35-K38 Diseases of appendix	0.715	0.285	0.000
L41 Parapsoriasis	0.714	0.286	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.714	0.286	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.714	0.286	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.714	0.286	0.000
E61 Deficiency of other nutrient elements	0.714	0.286	0.000
L40.4 Guttate psoriasis	0.713	0.287	0.000
L40.2 Acrodermatitis continua	0.713	0.287	0.000
B65-B83 Helminthiases	0.712	0.287	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.712	0.288	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.712	0.288	0.000
E32 Diseases of thymus	0.712	0.288	0.000
E30 Disorders of puberty, not elsewhere classified	0.712	0.288	0.000
E25 Adrenogenital disorders	0.712	0.288	0.000
E27.5 Adrenomedullary hyperfunction	0.712	0.288	0.000
E27.0 Other adrenocortical overactivity	0.712	0.288	0.000
B06 Rubella [German measles]	0.712	0.288	0.000
B05 Measles	0.712	0.288	0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.712	0.288	0.000
B04 Monkeypox	0.712	0.288	0.000
B03 Smallpox	0.712	0.288	0.000
K70-K77 Diseases of liver	0.711	0.289	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.289	0.710
L11 Other acantholytic disorders	0.710	0.289	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.290	0.710
B36.9 Superficial mycosis, unspecified	0.709	0.291	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.709	0.291	0.000
E50 Vitamin A deficiency	0.709	0.291	0.000
E60 Dietary zinc deficiency	0.709	0.291	0.000
E59 Dietary selenium deficiency	0.709	0.291	0.000
E54 Ascorbic acid deficiency	0.709	0.291	0.000
E52 Niacin deficiency [pellagra]	0.709	0.291	0.000
M06.2 Rheumatoid bursitis	0.000	0.293	0.706
M06.1 Adult-onset Still's disease	0.000	0.293	0.706
D74 Methaemoglobinaemia	0.706	0.294	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.706	0.294	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.706	0.294	0.000
K90.3 Pancreatic steatorrhoea	0.706	0.294	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.706	0.294	0.000
K90.1 Tropical sprue	0.706	0.294	0.000
L54 Erythema in diseases classified elsewhere	0.704	0.296	0.000
D68.5 Primary Thrombophilia	0.701	0.299	0.000
M05.2 Rheumatoid vasculitis	0.003	0.299	0.698
A65-A69 Other spirochaetal diseases	0.701	0.299	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.300	0.700
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.300	0.700
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.300	0.700
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.300	0.700
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.300	0.700
Chapter XVI Certain conditions originating in the perinatal period	0.700	0.300	0.000
B00 Herpesviral [herpes simplex] infections	0.697	0.303	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.696	0.304	0.000
E53.1 Pyridoxine deficiency	0.696	0.304	0.000
E53.0 Riboflavin deficiency	0.696	0.304	0.000
E58 Dietary calcium deficiency	0.692	0.308	0.000
D72.9 Disorder of white blood cells, unspecified	0.692	0.308	0.000
D72.0 Genetic anomalies of leukocytes	0.692	0.308	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.691	0.309	0.000
E55.9 Vitamin D deficiency, unspecified	0.691	0.309	0.000
B33 Other viral diseases, not elsewhere classified	0.688	0.311	0.000
B30 Viral conjunctivitis	0.688	0.311	0.000
B26 Mumps	0.688	0.311	0.000
E83 Disorders of mineral metabolism	0.689	0.311	0.000
E31.0 Autoimmune polyglandular failure	0.688	0.312	0.000
L24 Irritant contact dermatitis	0.686	0.314	0.000
L22 Diaper [napkin] dermatitis	0.686	0.314	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.685	0.315	0.000
E88 Other metabolic disorders	0.684	0.316	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.684	0.316	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.684	0.316	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.003	0.316	0.681
M05.1 Rheumatoid lung disease	0.003	0.316	0.681
M05.0 Felty's syndrome	0.003	0.316	0.681
B01.2 Varicella pneumonia	0.684	0.316	0.000
B37.7 Candidal septicaemia	0.683	0.317	0.000
D69.1 Qualitative platelet defects	0.683	0.317	0.000
D81 Combined immunodeficiencies	0.682	0.318	0.000
B25.2 Cytomegaloviral pancreatitis	0.680	0.320	0.000
B25.1 Cytomegaloviral hepatitis	0.680	0.320	0.000
K90.8 Other intestinal malabsorption	0.680	0.320	0.000
H80-H83 Diseases of inner ear	0.679	0.321	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.678	0.322	0.000
K70 Alcoholic liver disease	0.678	0.322	0.000
L10 Pemphigus	0.677	0.322	0.000
L14 Bullous disorders in diseases classified elsewhere	0.677	0.322	0.000
E05.8 Other thyrotoxicosis	0.677	0.323	0.000
D73 Diseases of spleen	0.677	0.323	0.000
D50-D53 Nutritional anaemias	0.675	0.325	0.000
M05.8 Other seropositive rheumatoid arthritis	0.003	0.325	0.673
M09 Juvenile arthritis in diseases classified elsewhere	0.007	0.326	0.667
M08 Juvenile arthritis	0.007	0.326	0.667
G04 Encephalitis, myelitis and encephalomyelitis	0.673	0.327	0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.672	0.328	0.000
D86.0 Sarcoidosis of lung	0.672	0.328	0.000
K37 Unspecified appendicitis	0.672	0.328	0.000
L27.9 Dermatitis due to unspecified substance taken internally	0.671	0.328	0.000
L27.8 Dermatitis due to other substances taken internally	0.671	0.328	0.000
G62.2 Polyneuropathy due to other toxic agents	0.669	0.330	0.000
E51.2 Wernicke's encephalopathy	0.667	0.333	0.000
K75 Other inflammatory liver diseases	0.666	0.334	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.334	0.666
M06.38 Rheumatoid nodule (Other)	0.000	0.334	0.666
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.334	0.666
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.334	0.666
M06.33 Rheumatoid nodule (Forearm)	0.000	0.334	0.666
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.334	0.666
G81 Hemiplegia	0.665	0.335	0.000
E73 Lactose intolerance	0.665	0.335	0.000
B25.8 Other cytomegaloviral diseases	0.664	0.336	0.000
Chapter XXII Codes for special purposes	0.663	0.337	0.000
B25.0 Cytomegaloviral pneumonitis	0.661	0.338	0.000
A80-A89 Viral infections of the central nervous system	0.660	0.340	0.000
D84 Other immunodeficiencies	0.657	0.342	0.000
E83.1 Disorders of iron metabolism	0.657	0.343	0.000
E28 Ovarian dysfunction	0.656	0.344	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.655	0.345	0.000
D82 Immunodeficiency associated with other major defects	0.655	0.345	0.000
E24.0 Pituitary-dependent Cushing's disease	0.654	0.346	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.653	0.347	0.000
L53 Other erythematous conditions	0.653	0.347	0.000
G00.8 Other bacterial meningitis	0.652	0.348	0.000
G00.3 Staphylococcal meningitis	0.652	0.348	0.000
G00.0 Haemophilus meningitis	0.652	0.348	0.000
E83.5 Disorders of calcium metabolism	0.652	0.348	0.000
E40-E46 Malnutrition	0.651	0.349	0.000
G57 Mononeuropathies of lower limb	0.650	0.350	0.000
K75.8 Other specified inflammatory liver diseases	0.648	0.352	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.647	0.353	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.647	0.353	0.000
E56 Other vitamin deficiencies	0.647	0.353	0.000
D69.9 Haemorrhagic condition, unspecified	0.644	0.356	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.644	0.356	0.000
L20 Atopic dermatitis	0.644	0.356	0.000
G31.8 Other specified degenerative diseases of nervous system	0.642	0.358	0.000
G62.8 Other specified polyneuropathies	0.641	0.359	0.000
K70.9 Alcoholic liver disease, unspecified	0.639	0.361	0.000
B27 Infectious mononucleosis	0.638	0.362	0.000
D68.6 Other Thrombophilia	0.636	0.364	0.000
L13.9 Bullous disorder, unspecified	0.636	0.364	0.000
L13.8 Other specified bullous disorders	0.636	0.364	0.000
L13.1 Subcorneal pustular dermatitis	0.636	0.364	0.000
K38 Other diseases of appendix	0.635	0.365	0.000
H90-H95 Other disorders of ear	0.634	0.366	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.368	0.632
L25 Unspecified contact dermatitis	0.627	0.372	0.000
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions	0.627	0.373	0.000
E04.8 Other specified non-toxic goitre	0.627	0.373	0.000
L12.0 Bullous pemphigoid	0.626	0.374	0.000
E20.9 Hypoparathyroidism, unspecified	0.626	0.374	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.625	0.375	0.000
H81 Disorders of vestibular function	0.625	0.375	0.000
H90 Conductive and sensorineural hearing loss	0.625	0.375	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.378	0.622
G37.5 Concentric sclerosis [Balo]	0.621	0.379	0.000
G37.4 Subacute necrotising myelitis	0.621	0.379	0.000
G37.2 Central pontine myelinolysis	0.621	0.379	0.000
G37.1 Central demyelination of corpus callosum	0.621	0.379	0.000
G37.0 Diffuse sclerosis	0.621	0.379	0.000
E73.9 Lactose intolerance, unspecified	0.620	0.380	0.000
L21.8 Other seborrhoeic dermatitis	0.620	0.380	0.000
L21.1 Seborrhoeic infantile dermatitis	0.620	0.380	0.000
L21.0 Seborrhoea capitis	0.620	0.380	0.000
D68.9 Coagulation defect, unspecified	0.619	0.381	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.619	0.381	0.000
E07 Other disorders of thyroid	0.616	0.382	0.002
A63.0 Anogenital (venereal) warts	0.618	0.382	0.000
B01.8 Varicella with other complications	0.613	0.387	0.000
B01.1 Varicella encephalitis	0.613	0.387	0.000
B01.0 Varicella meningitis	0.613	0.387	0.000
B50-B64 Protozoal diseases	0.613	0.387	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.611	0.389	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.390	0.610
D55 Anaemia due to enzyme disorders	0.610	0.390	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.610	0.390	0.000
E04.9 Non-toxic goitre, unspecified	0.608	0.392	0.000
B99-B99 Other infectious diseases	0.608	0.392	0.000
L44.0 Pityriasis rubra pilaris	0.606	0.394	0.000
L50.1 Idiopathic urticaria	0.605	0.395	0.000
L51.9 Erythema multiforme, unspecified	0.604	0.396	0.000
K75.4 Autoimmune hepatitis	0.603	0.397	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.603	0.397	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.603	0.397	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.603	0.397	0.000
G06.0 Intracranial abscess and granuloma	0.602	0.397	0.000
R26 Abnormalities of gait and mobility	0.600	0.400	0.000
D83 Common variable immunodeficiency	0.600	0.400	0.000
L23.8 Allergic contact dermatitis due to other agents	0.598	0.401	0.000
L23.7 Allergic contact dermatitis due to plants, except food	0.598	0.401	0.000
L23.6 Allergic contact dermatitis due to food in contact with the skin	0.598	0.401	0.000
L23.4 Allergic contact dermatitis due to dyes	0.598	0.401	0.000
L23.3 Allergic contact dermatitis due to drugs in contact with the skin	0.598	0.401	0.000
L23.2 Allergic contact dermatitis due to cosmetics	0.598	0.401	0.000
L23.0 Allergic contact dermatitis due to metals	0.598	0.401	0.000
B08.1 Molluscum contagiosum	0.598	0.401	0.000
E89.0 Postprocedural hypothyroidism	0.596	0.404	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.404	0.596
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.596	0.404	0.000
D57 Sickle-cell disorders	0.595	0.404	0.000
B36.8 Other specified superficial mycoses	0.595	0.405	0.000
B36.3 Black piedra	0.595	0.405	0.000
B36.2 White piedra	0.595	0.405	0.000
B36.1 Tinea nigra	0.595	0.405	0.000
B36.0 Pityriasis versicolor	0.595	0.405	0.000
D89.1 Cryoglobulinaemia	0.595	0.405	0.000
E63.9 Nutritional deficiency, unspecified	0.592	0.407	0.000
G82 Paraplegia and tetraplegia	0.592	0.408	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.592	0.408	0.000
G11 Hereditary ataxia	0.590	0.410	0.000
B94 Sequelae of other and unspecified infectious and parasitic diseases	0.590	0.410	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.589	0.411	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.589	0.411	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.589	0.411	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.589	0.411	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.589	0.411	0.000
G23 Other degenerative diseases of basal ganglia	0.587	0.413	0.000
B00.4 Herpesviral encephalitis	0.587	0.413	0.000
L23.5 Allergic contact dermatitis due to other chemical products	0.587	0.413	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.585	0.415	0.000
D59.8 Other acquired haemolytic anaemias	0.585	0.415	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.585	0.415	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.585	0.415	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.585	0.415	0.000
D59.3 Haemolytic-uraemic syndrome	0.585	0.415	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.585	0.415	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.585	0.415	0.000
E65-E68 Obesity and other hyperalimentation	0.585	0.415	0.000
G21 Secondary Parkinsonism	0.585	0.415	0.000
E31.9 Polyglandular dysfunction, unspecified	0.585	0.415	0.000
E31.8 Other polyglandular dysfunction	0.585	0.415	0.000
E31.1 Polyglandular hyperfunction	0.585	0.415	0.000
E55.0 Rickets, active	0.585	0.415	0.000
G51 Facial nerve disorders	0.584	0.416	0.000
L50.0 Allergic urticaria	0.584	0.416	0.000
H80 Otosclerosis	0.583	0.417	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.582	0.418	0.000
G52 Disorders of other cranial nerves	0.582	0.418	0.000
H81.0 Meniere's disease	0.582	0.418	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.582	0.418	0.000
L27.2 Dermatitis due to ingested food	0.581	0.418	0.000
K70.4 Alcoholic hepatic failure	0.581	0.419	0.000
G31.2 Degeneration of nervous system due to alcohol	0.580	0.420	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.578	0.421	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.578	0.422	0.000
G22 Parkinsonism in diseases classified elsewhere	0.578	0.422	0.000
G70-G73 Diseases of myoneural junction and muscle	0.577	0.423	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.577	0.423	0.000
H90.0 Conductive hearing loss, bilateral	0.576	0.424	0.000
M12 Other specific arthropathies	0.007	0.424	0.569
E34.9 Endocrine disorder, unspecified	0.575	0.425	0.000
D68.8 Other specified coagulation defects	0.575	0.425	0.000
E51.9 Thiamine deficiency, unspecified	0.575	0.425	0.000
E51.8 Other manifestations of thiamine deficiency	0.575	0.425	0.000
E51.1 Beriberi	0.575	0.425	0.000
D68.0 Von Willebrand's disease	0.575	0.425	0.000
K70.3 Alcoholic cirrhosis of liver	0.574	0.426	0.000
G03 Meningitis due to other and unspecified causes	0.574	0.426	0.000
E61.2 Magnesium deficiency	0.573	0.427	0.000
G57.0 Lesion of sciatic nerve	0.572	0.428	0.000
A59 Trichomoniasis	0.571	0.429	0.000
A56 Other sexually transmitted chlamydial diseases	0.571	0.429	0.000
A54 Gonococcal infection	0.571	0.429	0.000
A53 Other and unspecified syphilis	0.571	0.429	0.000
A52 Late syphilis	0.571	0.429	0.000
A51 Early syphilis	0.571	0.429	0.000
A50 Congenital syphilis	0.571	0.429	0.000
A64 Unspecified sexually transmitted disease	0.571	0.429	0.000
A58 Granuloma inguinale	0.571	0.429	0.000
A57 Chancroid	0.571	0.429	0.000
A55 Chlamydial lymphogranuloma (venereum)	0.571	0.429	0.000
L23.9 Allergic contact dermatitis, unspecified cause	0.570	0.430	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.570	0.430	0.000
D68.2 Hereditary deficiency of other clotting factors	0.570	0.430	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.570	0.430	0.000
G58 Other mononeuropathies	0.569	0.431	0.000
E26 Hyperaldosteronism	0.568	0.432	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.568	0.432	0.000
H81.3 Other peripheral vertigo	0.562	0.438	0.000
G81.9 Hemiplegia, unspecified	0.562	0.438	0.000
E22 Hyperfunction of pituitary gland	0.560	0.440	0.000
A15-A19 Tuberculosis	0.559	0.441	0.000
B24 Unspecified human immunodeficiency virus [HIV] disease	0.559	0.441	0.000
E20.8 Other hypoparathyroidism	0.559	0.441	0.000
E20.1 Pseudohypoparathyroidism	0.559	0.441	0.000
E20.0 Idiopathic hypoparathyroidism	0.559	0.441	0.000
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases	0.558	0.441	0.000
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms	0.558	0.441	0.000
H90.5 Sensorineural hearing loss, unspecified	0.558	0.442	0.000
G31.0 Circumscribed brain atrophy	0.555	0.444	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.554	0.446	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.552	0.447	0.000
L44.9 Papulosquamous disorder, unspecified	0.551	0.448	0.000
L44.8 Other specified papulosquamous disorders	0.551	0.448	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.551	0.448	0.000
L44.3 Lichen ruber moniliformis	0.551	0.448	0.000
L44.2 Lichen striatus	0.551	0.448	0.000
L44.1 Lichen nitidus	0.551	0.448	0.000
K73 Chronic hepatitis, not elsewhere classified	0.551	0.449	0.000
D68.1 Hereditary factor XI deficiency	0.551	0.449	0.000
D89.3 Immune reconstitution syndrome	0.550	0.449	0.000
E24.8 Other Cushing's syndrome	0.550	0.450	0.000
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases	0.549	0.451	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.452	0.548
B15-B19 Viral hepatitis	0.548	0.452	0.000
B08.8 Other specified viral infections characterised by skin and mucous membrane lesions	0.547	0.453	0.000
B08.5 Enteroviral vesicular pharyngitis	0.547	0.453	0.000
B08.4 Enteroviral vesicular stomatitis with exanthem	0.547	0.453	0.000
B08.3 Erythema infectiosum [fifth disease]	0.547	0.453	0.000
B08.2 Exanthema subitum [sixth disease]	0.547	0.453	0.000
B08.0 Other orthopoxvirus infections	0.547	0.453	0.000
L53.0 Toxic erythema	0.547	0.453	0.000
B91 Sequelae of poliomyelitis	0.547	0.453	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations