TreeWAS – Variant ID: rs5415

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.750	0.250	0.000
I10-I15 Hypertensive diseases	0.143	0.857	0.000
I13 Hypertensive heart and renal disease	0.109	0.891	0.000
I11 Hypertensive heart disease	0.098	0.902	0.000
I15 Secondary hypertension	0.093	0.907	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.084	0.916	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.083	0.917	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.082	0.917	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.078	0.922	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.922	0.078
I13.1 Hypertensive heart and renal disease with renal failure	0.076	0.924	0.000
I15.9 Seconday hypertension, unspecified	0.070	0.930	0.000
I15.0 Renovascular hypertension	0.066	0.934	0.000
I15.2 Hypertension secondary to endocrine disorders	0.064	0.936	0.000
I15.8 Other secondary hypertension	0.064	0.936	0.000
I15.1 Hypertension secondary to other renal disorders	0.062	0.938	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.949	0.050
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.957	0.043
K42.9 Umbilical hernia without obstruction or gangrene	0.040	0.960	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.037	0.962	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.964	0.036
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.964	0.036
E16.4 Abnormal secretion of gastrin	0.000	0.964	0.036
E16.3 Increased secretion of glucagon	0.000	0.964	0.036
I12 Hypertensive renal disease	0.034	0.966	0.000
E16.1 Other hypoglycaemia	0.000	0.967	0.032
Y86 Sequelae of other accidents	0.000	0.971	0.029
C54.1 Endometrium	0.025	0.975	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.979	0.021
E15 Nondiabetic hypoglycaemic coma	0.000	0.985	0.015
K42 Umbilical hernia	0.014	0.986	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.000	0.987	0.013
D21 Other benign neoplasms of connective and other soft tissue	0.000	0.987	0.013
D21.9 Connective and other soft tissue, unspecified	0.000	0.987	0.013
D21.0 Connective and other soft tissue of head, face and neck	0.000	0.987	0.013
K42.1 Umbilical hernia with gangrene	0.011	0.989	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.000	0.989	0.011
D21.4 Connective and other soft tissue of abdomen	0.000	0.989	0.011
C54 Malignant neoplasm of corpus uteri	0.011	0.989	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.989	0.011
D21.3 Connective and other soft tissue of thorax	0.000	0.990	0.010
T93.2 Sequelae of other fractures of lower limb	0.000	0.990	0.010
T93 Sequelae of injuries of lower limb	0.000	0.990	0.010
I12.9 Hypertensive renal disease without renal failure	0.009	0.990	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.000	0.990	0.010
N30.8 Other cystitis	0.000	0.991	0.009
D21.5 Connective and other soft tissue of pelvis	0.000	0.991	0.009
E23.2 Diabetes insipidus	0.009	0.991	0.000
T93.0 Sequelae of open wound of lower limb	0.000	0.991	0.009
E23.0 Hypopituitarism	0.009	0.991	0.000
E23 Hypofunction and other disorders of pituitary gland	0.009	0.991	0.000
D21.6 Connective and other soft tissue of trunk, unspecified	0.000	0.992	0.008
E23.7 Disorder of pituitary gland, unspecified	0.008	0.992	0.000
C54.8 Overlapping lesion of corpus uteri	0.008	0.992	0.000
C54.3 Fundus uteri	0.008	0.992	0.000
C54.2 Myometrium	0.008	0.992	0.000
C54.0 Isthmus uteri	0.008	0.992	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.008	0.992	0.000
I85.9 Oesophageal varices without bleeding	0.000	0.992	0.008
K05.3 Chronic periodontitis	0.008	0.992	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.007	0.992	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.000	0.993	0.007
T93.1 Sequelae of fracture of femur	0.000	0.993	0.007
C54.9 Corpus uteri, unspecified	0.007	0.993	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.000	0.993	0.007
I77.1 Stricture of artery	0.000	0.993	0.007
E23.6 Other disorders of pituitary gland	0.007	0.993	0.000
N48.1 Balanoposthitis	0.007	0.993	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.006	0.994	0.000
E23.1 Drug-induced hypopituitarism	0.006	0.994	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.000	0.994	0.006
K04.8 Radicular cyst	0.006	0.994	0.000
N48.8 Other specified disorders of penis	0.006	0.994	0.000
R27.0 Ataxia, unspecified	0.006	0.994	0.000
K82.4 Cholesterolosis of gallbladder	0.000	0.994	0.006
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.000	0.994	0.006
R27.8 Other and unspecified lack of coordination	0.005	0.995	0.000
Z63.0 Problems in relationship with spouse or partner	0.005	0.995	0.000
Z56.0 Unemployment, unspecified	0.005	0.995	0.000
Z63 Other problems related to primary support group, including family circumstances	0.005	0.995	0.000
R27 Other lack of coordination	0.005	0.995	0.000
Z56 Problems related to employment and unemployment	0.005	0.995	0.000
I77 Other disorders of arteries and arterioles	0.000	0.995	0.005
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.995	0.005
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.005	0.995	0.000
N48 Other disorders of penis	0.005	0.995	0.000
Z61 Problems related to negative life events in childhood	0.005	0.995	0.000
Y89 Sequelae of other external causes	0.000	0.995	0.004
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.995	0.005
T93.8 Sequelae of other specified injuries of lower limb	0.000	0.996	0.004
I85 Oesophageal varices	0.000	0.996	0.004
Z56.6 Other physical and mental strain related to work	0.004	0.996	0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.000	0.996	0.004
N48.3 Priapism	0.004	0.996	0.000
I77.2 Rupture of artery	0.000	0.996	0.004
N48.0 Leukoplakia of penis	0.004	0.996	0.000
N48.4 Impotence of organic origin	0.004	0.996	0.000
Z63.7 Other stressful life events affecting family and household	0.004	0.996	0.000
Z63.6 Dependent relative needing care at home	0.004	0.996	0.000
Z65 Problems related to other psychosocial circumstances	0.004	0.996	0.000
Z64 Problems related to certain psychosocial circumstances	0.004	0.996	0.000
H16.0 Corneal ulcer	0.004	0.996	0.000
I85.0 Oesophageal varices with bleeding	0.000	0.996	0.004
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.004	0.996	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.996	0.004
Z63.5 Disruption of family by separation and divorce	0.004	0.996	0.000
Y87.0 Sequelae of intentional self-harm	0.000	0.996	0.004
Z61.8 Other negative life events in childhood	0.004	0.996	0.000
Z61.6 Problems related to alleged physical abuse of child	0.004	0.996	0.000
Z59 Problems related to housing and economic circumstances	0.004	0.996	0.000
T91.1 Sequelae of fracture of spine	0.000	0.996	0.004
W08.0 Home	0.000	0.996	0.004
Z56.4 Discord with boss and workmates	0.004	0.996	0.000
Z63.9 Problem related to primary support group, unspecified	0.004	0.996	0.000
Z63.3 Absence of family member	0.004	0.996	0.000
Z63.2 Inadequate family support	0.004	0.996	0.000
Z63.1 Problems in relationship with parents and in-laws	0.004	0.996	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.000	0.996	0.004
M13.0 Polyarthritis, unspecified	0.004	0.996	0.000
T91 Sequelae of injuries of neck and trunk	0.000	0.996	0.004
F50.9 Eating disorder, unspecified	0.004	0.996	0.000
Z64.0 Problems related to unwanted pregnancy	0.004	0.996	0.000
Z56.5 Uncongenial work	0.004	0.996	0.000
Z56.2 Threat of job loss	0.004	0.996	0.000
Z56.1 Change of job	0.004	0.996	0.000
Z57 Occupational exposure to risk-factors	0.004	0.996	0.000
Y89.9 Sequelae of unspecified external cause	0.000	0.996	0.004
I77.6 Arteritis, unspecified	0.000	0.996	0.004
I77.5 Necrosis of artery	0.000	0.996	0.004
I77.4 Coeliac artery compression syndrome	0.000	0.996	0.004
Z63.8 Other specified problems related to primary support group	0.004	0.996	0.000
Z57.2 Occupational exposure to dust	0.004	0.996	0.000
Z65.8 Other specified problems related to psychosocial circumstances	0.004	0.996	0.000
I77.3 Arterial fibromuscular dysplasia	0.000	0.996	0.004
Z62 Other problems related to upbringing	0.004	0.996	0.000
Z55 Problems related to education and literacy	0.004	0.996	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.004	0.996	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.000	0.996	0.004
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.003	0.996	0.000
Z61.9 Negative life events in childhood, unspecified	0.003	0.996	0.000
Z61.7 Personal frightening experience in childhood	0.003	0.996	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.003	0.996	0.000
Z61.2 Altered pattern of family relationships in childhood	0.003	0.996	0.000
Z61.1 Removal from home in childhood	0.003	0.996	0.000
Z61.0 Loss of love relationship in childhood	0.003	0.996	0.000
Y89.1 Sequelae of war operations	0.000	0.996	0.003
Y89.0 Sequelae of legal intervention	0.000	0.996	0.003
V23.4 Driver injured in traffic accident	0.004	0.996	0.000
H16 Keratitis	0.004	0.996	0.000
I12.0 Hypertensive renal disease with renal failure	0.003	0.996	0.000
Z65.3 Problems related to other legal circumstances	0.003	0.996	0.000
F60.3 Emotionally unstable personality disorder	0.003	0.997	0.000
I77.8 Other specified disorders of arteries and arterioles	0.000	0.997	0.003
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.003	0.997	0.000
T95 Sequelae of burns, corrosions and frostbite	0.000	0.997	0.003
Z56.7 Other and unspecified problems related to employment	0.003	0.997	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.000	0.997	0.003
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.997	0.003
Q66.8 Other congenital deformities of feet	0.003	0.997	0.000
Z56.3 Stressful work schedule	0.003	0.997	0.000
M21.0 Valgus deformity, not elsewhere classified	0.000	0.997	0.003
Z57.8 Occupational exposure to other risk-factors	0.003	0.997	0.000
F50.0 Anorexia nervosa	0.003	0.997	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.003	0.997	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.003	0.997	0.000
Z65.4 Victim of crime and terrorism	0.003	0.997	0.000
Z65.2 Problems related to release from prison	0.003	0.997	0.000
Z65.1 Imprisonment and other incarceration	0.003	0.997	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.003	0.997	0.000
Z64.4 Discord with counsellors	0.003	0.997	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.003	0.997	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.003	0.997	0.000
Z64.1 Problems related to multiparity	0.003	0.997	0.000
O20.0 Threatened abortion	0.000	0.997	0.003
Z59.0 Homelessness	0.003	0.997	0.000
Z58 Problems related to physical environment	0.003	0.997	0.000
Z59.4 Lack of adequate food	0.003	0.997	0.000
I77.0 Arteriovenous fistula, acquired	0.000	0.997	0.003
H16.8 Other keratitis	0.003	0.997	0.000
N48.9 Disorder of penis, unspecified	0.003	0.997	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.003	0.997	0.000
F50 Eating disorders	0.003	0.997	0.000
Y88 Sequelae of surgical and medical care as external cause	0.000	0.997	0.003
Z59.2 Discord with neighbours, lodgers and landlord	0.003	0.997	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.997	0.003
H16.2 Keratoconjunctivitis	0.003	0.997	0.000
Z59.7 Insufficient social insurance and welfare support	0.003	0.997	0.000
Z59.6 Low income	0.003	0.997	0.000
Z59.5 Extreme poverty	0.003	0.997	0.000
Z59.3 Problems related to living in residential institution	0.003	0.997	0.000
T18.1 Foreign body in oesophagus	0.003	0.997	0.000
T91.3 Sequelae of injury of spinal cord	0.000	0.997	0.003
Y87.1 Sequelae of assault	0.000	0.997	0.003
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.000	0.997	0.003
M13.08 Polyarthritis, unspecified (Other)	0.003	0.997	0.000
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M13.03 Polyarthritis, unspecified (Forearm)	0.003	0.997	0.000
M13.02 Polyarthritis, unspecified (Upper arm)	0.003	0.997	0.000
M13.01 Polyarthritis, unspecified (Shoulder region)	0.003	0.997	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.000	0.997	0.003
T91.4 Sequelae of injury of intrathoracic organs	0.000	0.997	0.003
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.000	0.997	0.003
Y87.2 Sequelae of events of undetermined intent	0.000	0.997	0.003
M13.09 Polyarthritis, unspecified (Site unspecified)	0.003	0.997	0.000
M21.1 Varus deformity, not elsewhere classified	0.000	0.997	0.003
Z57.9 Occupational exposure to unspecified risk-factor	0.003	0.997	0.000
Z57.7 Occupational exposure to vibration	0.003	0.997	0.000
Z57.6 Occupational exposure to extreme temperature	0.003	0.997	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.003	0.997	0.000
Z57.1 Occupational exposure to radiation	0.003	0.997	0.000
Z57.0 Occupational exposure to noise	0.003	0.997	0.000
M13.06 Polyarthritis, unspecified (Lower leg)	0.003	0.997	0.000
Z58.7 Exposure to tobacco smoke	0.003	0.997	0.000
Z59.1 Inadequate housing	0.003	0.997	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.003	0.997	0.000
Z55.8 Other problems relating to education and literacy	0.003	0.997	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.003	0.997	0.000
Z55.3 Underachievement in school	0.003	0.997	0.000
Z55.2 Failed examinations	0.003	0.997	0.000
Z55.1 Schooling unavailable and unattainable	0.003	0.997	0.000
Z55.0 Illiteracy and low-level literacy	0.003	0.997	0.000
Z62.9 Problem related to upbringing, unspecified	0.003	0.997	0.000
Z62.8 Other specified problems related to upbringing	0.003	0.997	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.003	0.997	0.000
Z62.5 Other problems related to neglect in upbringing	0.003	0.997	0.000
Z62.4 Emotional neglect of child	0.003	0.997	0.000
Z62.3 Hostility towards and scapegoating of child	0.003	0.997	0.000
Z62.2 Institutional upbringing	0.003	0.997	0.000
Z62.1 Parental overprotection	0.003	0.997	0.000
Z62.0 Inadequate parental supervision and control	0.003	0.997	0.000
Z63.4 Disappearance and death of family member	0.003	0.997	0.000
K25.7 Chronic without haemorrhage or perforation	0.000	0.997	0.003
T94 Sequelae of injuries involving multiple and unspecified body regions	0.000	0.997	0.003
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.997	0.003
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.997	0.003
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.000	0.997	0.003
H16.4 Corneal neovascularisation	0.003	0.997	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.003	0.997	0.000
S06.5 Traumatic subdural haemorrhage	0.000	0.997	0.003
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.997	0.003
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.000	0.997	0.003
M43.16 Spondylolisthesis (Lumbar region)	0.003	0.997	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.000	0.997	0.003
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.000	0.997	0.003
Z57.3 Occupational exposure to other air contaminants	0.003	0.997	0.000
H16.9 Keratitis, unspecified	0.003	0.997	0.000
M13.04 Polyarthritis, unspecified (Hand)	0.003	0.997	0.000
T98 Sequelae of other and unspecified effects of external causes	0.000	0.997	0.003
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.997	0.003
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.000	0.997	0.003
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.000	0.997	0.003
H16.3 Interstitial and deep keratitis	0.003	0.997	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.000	0.997	0.003
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.000	0.997	0.003
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.997	0.003
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.997	0.003
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.997	0.003
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.997	0.003
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.997	0.003
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.997	0.003
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.997	0.003
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.997	0.003
F50.2 Bulimia nervosa	0.003	0.997	0.000
M24.56 Contracture of joint (Lower leg)	0.000	0.997	0.003
N48.2 Other inflammatory disorders of penis	0.003	0.997	0.000
Y85 Sequelae of transport accidents	0.000	0.997	0.003
Z58.9 Problem related to physical environment, unspecified	0.002	0.997	0.000
Z58.6 Inadequate drinking-water supply	0.002	0.997	0.000
Z58.4 Exposure to radiation	0.002	0.997	0.000
Z58.3 Exposure to soil pollution	0.002	0.997	0.000
Z58.2 Exposure to water pollution	0.002	0.997	0.000
Z58.0 Exposure to noise	0.002	0.997	0.000
M21 Other acquired deformities of limbs	0.000	0.997	0.003
N48.5 Ulcer of penis	0.002	0.997	0.000
F50.8 Other eating disorders	0.002	0.997	0.000
F50.5 Vomiting associated with other psychological disturbances	0.002	0.997	0.000
F50.4 Overeating associated with other psychological disturbances	0.002	0.997	0.000
F50.3 Atypical bulimia nervosa	0.002	0.997	0.000
F50.1 Atypical anorexia nervosa	0.002	0.997	0.000
Z58.5 Exposure to other pollution	0.002	0.997	0.000
S06.2 Diffuse brain injury	0.000	0.997	0.002
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use	0.000	0.997	0.002
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.997	0.002
M21.4 Flat foot [pes planus] (acquired)	0.000	0.997	0.002
S06.8 Other intracranial injuries	0.000	0.997	0.002
C55 Malignant neoplasm of uterus, part unspecified	0.002	0.997	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.998	0.002
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.998	0.002
W55.0 Home	0.000	0.998	0.002
N05.9 Unspecified	0.002	0.998	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.998	0.002
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.998	0.002
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.998	0.002
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.998	0.002
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
M21.8 Other specified acquired deformities of limbs	0.000	0.998	0.002
T94.0 Sequelae of injuries involving multiple body regions	0.000	0.998	0.002
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.000	0.998	0.002
Z60 Problems related to social environment	0.002	0.998	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.000	0.998	0.002
T91.2 Sequelae of other fracture of thorax and pelvis	0.000	0.998	0.002
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.000	0.998	0.002
S06 Intracranial injury	0.000	0.998	0.002
Q79.6 Ehlers-Danlos syndrome	0.000	0.998	0.002
S13.4 Sprain and strain of cervical spine	0.002	0.998	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.998	0.002
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.000	0.998	0.002
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.998	0.002
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.000	0.998	0.002
J00 Acute nasopharyngitis [common cold]	0.002	0.998	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
D12.4 Descending colon	0.002	0.998	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.998	0.002
T98.2 Sequelae of certain early complications of trauma	0.000	0.998	0.002
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.000	0.998	0.002
H21 Other disorders of iris and ciliary body	0.002	0.998	0.000
M21.9 Acquired deformity of limb, unspecified	0.000	0.998	0.002
M21.2 Flexion deformity	0.000	0.998	0.002
Z59.8 Other problems relating to housing and economic circumstances	0.002	0.998	0.000
C51-C58 Malignant neoplasms of female genital organs	0.002	0.998	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
M85.8 Other specified disorders of bone density and structure	0.000	0.998	0.002
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.998	0.002
O20 Haemorrhage in early pregnancy	0.000	0.998	0.002
T90 Sequelae of injuries of head	0.000	0.998	0.002
K65.8 Other peritonitis	0.000	0.998	0.002
C50.1 Central portion of breast	0.002	0.998	0.000
Z58.1 Exposure to air pollution	0.002	0.998	0.000
T90.9 Sequelae of unspecified injury of head	0.000	0.998	0.002
M21.24 Flexion deformity (Hand)	0.000	0.998	0.002
C15.9 Oesophagus, unspecified	0.000	0.998	0.002
Z58.8 Other problems related to physical environment	0.002	0.998	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.998	0.002
Q66 Congenital deformities of feet	0.002	0.998	0.000
M24.54 Contracture of joint (Hand)	0.000	0.998	0.002
T94.1 Sequelae of injuries, not specified by body region	0.000	0.998	0.002
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.998	0.002
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.998	0.002
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.998	0.002
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.998	0.002
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.998	0.002
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.998	0.002
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.998	0.002
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.998	0.002
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.998	0.002
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.002
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.998	0.002
M21.6 Other acquired deformities of ankle and foot	0.000	0.998	0.002
Z60.9 Problem related to social environment, unspecified	0.002	0.998	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.002	0.998	0.000
Z60.8 Other problems related to social environment	0.002	0.998	0.000
H21.4 Pupillary membranes	0.002	0.998	0.000
T92 Sequelae of injuries of upper limb	0.000	0.998	0.002
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.000	0.998	0.002
T90.1 Sequelae of open wound of head	0.000	0.998	0.002
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.998	0.002
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.998	0.002
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.998	0.002
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.998	0.002
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.998	0.002
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.998	0.002
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.002	0.998	0.000
Z60.4 Social exclusion and rejection	0.002	0.998	0.000
Z60.3 Acculturation difficulty	0.002	0.998	0.000
Z60.1 Atypical parenting situation	0.002	0.998	0.000
Z60.0 Problems of adjustment to life-cycle transitions	0.002	0.998	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.000	0.998	0.002
S06.7 Intracranial injury with prolonged coma	0.000	0.998	0.002
S06.4 Epidural haemorrhage	0.000	0.998	0.002
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.002	0.998	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.002	0.998	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.000	0.998	0.002
H18.8 Other specified disorders of cornea	0.002	0.998	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.000	0.998	0.002
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.998	0.002
S06.1 Traumatic cerebral oedema	0.000	0.998	0.002
T92.4 Sequelae of injury of nerve of upper limb	0.000	0.998	0.002
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.002	0.998	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.002	0.998	0.000
M24.5 Contracture of joint	0.000	0.998	0.002
Q66.7 Pes cavus	0.002	0.998	0.000
T68 Hypothermia	0.000	0.998	0.002
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.000	0.998	0.002
T90.3 Sequelae of injury of cranial nerves	0.000	0.998	0.002
Y85.9 Sequelae of other and unspecified transport accidents	0.000	0.998	0.002
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.000	0.998	0.002
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.000	0.998	0.002
H21.3 Cyst of iris, ciliary body and anterior chamber	0.002	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.000	0.998	0.002
S69.9 Unspecified injury of wrist and hand	0.002	0.998	0.000
M21.29 Flexion deformity (Site unspecified)	0.000	0.998	0.002
M21.28 Flexion deformity (Other)	0.000	0.998	0.002
M21.27 Flexion deformity (Ankle and foot)	0.000	0.998	0.002
M21.22 Flexion deformity (Upper arm)	0.000	0.998	0.002
M21.21 Flexion deformity (Shoulder region)	0.000	0.998	0.002
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.000	0.998	0.002
M21.98 Acquired deformity of limb, unspecified-Other	0.000	0.998	0.002
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.000	0.998	0.002
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.000	0.998	0.002
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.000	0.998	0.002
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.000	0.998	0.002
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.000	0.998	0.002
M24.51 Contracture of joint (Shoulder region)	0.000	0.998	0.002
M85.83 Other specified disorders of bone density and structure (Forearm)	0.000	0.998	0.002
M21.20 Flexion deformity (Multiple sites)	0.000	0.998	0.002
M85.88 Other specified disorders of bone density and structure (Other)	0.000	0.998	0.002
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.998	0.002
C58 Malignant neoplasm of placenta	0.002	0.998	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.000	0.998	0.002
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.000	0.998	0.002
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.000	0.998	0.002
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
S06.0 Concussion	0.000	0.998	0.002
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.000	0.998	0.002
M21.3 Wrist or foot drop (acquired)	0.000	0.998	0.002
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.002	0.998	0.000
M21.26 Flexion deformity (Lower leg)	0.000	0.998	0.002
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.000	0.998	0.002
S06.9 Intracranial injury, unspecified	0.000	0.998	0.002
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.998	0.002
H21.2 Degeneration of iris and ciliary body	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
C51 Malignant neoplasm of vulva	0.002	0.998	0.000
T90.0 Sequelae of superficial injury of head	0.000	0.998	0.002
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.002	0.998	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.002	0.998	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.000	0.998	0.002
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.998	0.002
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.998	0.002
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.998	0.002
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.998	0.002
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.998	0.002
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.998	0.002
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.998	0.002
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.998	0.002
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.000	0.998	0.002
C51.0 Labium majus	0.002	0.998	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.002	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
W08 Fall involving other furniture	0.000	0.998	0.002
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.002	0.998	0.000
M21.23 Flexion deformity (Forearm)	0.000	0.998	0.002
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
R30.0 Dysuria	0.000	0.998	0.002
S06.3 Focal brain injury	0.000	0.998	0.002
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.000	0.998	0.002
O42.9 Premature rupture of membranes, unspecified	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.001	0.998	0.001
W55.7 Farm	0.000	0.998	0.002
T90.5 Sequelae of intracranial injury	0.000	0.998	0.002
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.002	0.998	0.000
H21.0 Hyphaema	0.002	0.998	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.002	0.998	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
R30.9 Painful micturition, unspecified	0.000	0.998	0.002
M13.80 Other specified arthritis (Multiple sites)	0.002	0.998	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.998	0.001
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.998	0.001
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.998	0.001
H21.1 Other vascular disorders of iris and ciliary body	0.002	0.998	0.000
M13.8 Other specified arthritis	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
V49.9 Car occupant [any] injured in unspecified traffic accident	0.002	0.998	0.000
C52 Malignant neoplasm of vagina	0.002	0.998	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.998	0.001
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.998	0.001
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.998	0.001
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.998	0.001
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.998	0.001
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.998	0.001
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.998	0.001
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.998	0.001
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.998	0.002
M47.12 Other spondylosis with myelopathy (Cervical region)	0.002	0.998	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.998	0.001
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.998	0.002
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.000	0.998	0.002
M24.59 Contracture of joint (Site unspecified)	0.000	0.998	0.002
M24.58 Contracture of joint (Other)	0.000	0.998	0.002
M24.53 Contracture of joint (Forearm)	0.000	0.998	0.002
M24.50 Contracture of joint (Multiple sites)	0.000	0.998	0.002
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.998	0.002
C82.3 Follicular lymphoma grade IIIa	0.000	0.998	0.002
M00.9 Pyogenic arthritis, unspecified	0.002	0.998	0.000
O63.0 Prolonged first stage (of labour)	0.000	0.998	0.002
V23.9 Unspecified motorcycle rider injured in traffic accident	0.001	0.998	0.000
V23.5 Passenger injured in traffic accident	0.001	0.998	0.000
V23.3 Person injured while boarding or alighting	0.001	0.998	0.000
V23.2 Unspecified motorcycle rider injured in nontraffic accident	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations