TreeWAS – Variant ID: rs56364616

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S52.50 Fracture of lower end of radius (closed)	0.000	0.000	1.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.000	0.000	1.000
S52.6 Fracture of lower end of both ulna and radius	0.000	0.000	1.000
S52.5 Fracture of lower end of radius	0.000	0.001	0.999
S52 Fracture of forearm	0.000	0.001	0.999
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.004	0.996
S52.61 Fracture of lower end of both ulna and radius (open)	0.000	0.059	0.941
M81.9 Osteoporosis, unspecified	0.000	0.093	0.907
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.155	0.845
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.188	0.812
S52.8 Fracture of other parts of forearm	0.000	0.225	0.775
S52.4 Fracture of shafts of both ulna and radius	0.000	0.225	0.775
S52.3 Fracture of shaft of radius	0.000	0.245	0.755
S52.7 Multiple fractures of forearm	0.000	0.282	0.718
S52.9 Fracture of forearm, part unspecified	0.000	0.284	0.716
S52.51 Fracture of lower end of radius (open)	0.000	0.311	0.689
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.319	0.681
S52.1 Fracture of upper end of radius	0.000	0.343	0.657
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.350	0.650
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.350	0.650
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.350	0.650
S52.0 Fracture of upper end of ulna	0.000	0.352	0.648
M81 Osteoporosis without pathological fracture	0.000	0.382	0.618
S52.80 Fracture of other parts of forearm (closed)	0.000	0.385	0.614
S52.40 Fracture of shafts of both ulna and radius (closed)	0.000	0.386	0.614
S82.00 Fracture of patella (closed)	0.000	0.401	0.599
S82.0 Fracture of patella	0.000	0.404	0.596
S82 Fracture of lower leg, including ankle	0.000	0.408	0.592
S52.30 Fracture of shaft of radius (closed)	0.000	0.420	0.580
M81.98 Osteoporosis, unspecified (Other)	0.000	0.424	0.576
S82.8 Fractures of other parts of lower leg	0.000	0.430	0.570
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.441	0.559
S52.81 Fracture of other parts of forearm (open)	0.000	0.444	0.556
S52.41 Fracture of shafts of both ulna and radius (open)	0.000	0.444	0.555
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.458	0.541
S52.31 Fracture of shaft of radius (open)	0.000	0.459	0.541
S82.5 Fracture of medial malleolus	0.000	0.460	0.540
S82.1 Fracture of upper end of tibia	0.000	0.479	0.521
S52.01 Fracture of upper end of ulna (open)	0.000	0.483	0.517
S52.70 Multiple fractures of forearm (closed)	0.000	0.484	0.516
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.485	0.515
S52.71 Multiple fractures of forearm (open)	0.000	0.485	0.515
S52.91 Fracture of forearm, part unspecified (open)	0.000	0.486	0.513
S52.90 Fracture of forearm, part unspecified (closed)	0.000	0.486	0.513
S52.2 Fracture of shaft of ulna	0.001	0.491	0.509
S82.50 Fracture of medial malleolus (closed)	0.000	0.494	0.506
M81.4 Drug-induced osteoporosis	0.000	0.515	0.485
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.000	0.518	0.482
S82.01 Fracture of patella (open)	0.000	0.520	0.480
S82.7 Multiple fractures of lower leg	0.000	0.527	0.473
S52.11 Fracture of upper end of radius (open)	0.000	0.529	0.471
S82.4 Fracture of fibula alone	0.000	0.530	0.470
M81.2 Osteoporosis of disuse	0.000	0.532	0.468
S82.10 Fracture of upper end of tibia (closed)	0.000	0.532	0.468
S82.3 Fracture of lower end of tibia	0.000	0.544	0.456
S82.6 Fracture of lateral malleolus	0.000	0.545	0.455
M81.0 Postmenopausal osteoporosis	0.000	0.548	0.452
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.555	0.445
M81.8 Other osteoporosis	0.000	0.557	0.443
M81.6 Localised osteoporosis [Lequesne]	0.000	0.557	0.443
M81.5 Idiopathic osteoporosis	0.000	0.557	0.443
M81.1 Postoophorectomy osteoporosis	0.000	0.557	0.443
S82.9 Fracture of lower leg, part unspecified	0.000	0.575	0.425
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.583	0.417
S52.10 Fracture of upper end of radius (closed)	0.000	0.587	0.412
S82.86 Maisonneuve's fracture	0.000	0.591	0.409
S82.70 Multiple fractures of lower leg (closed)	0.000	0.613	0.387
S82.40 Fracture of fibula alone (closed)	0.000	0.618	0.382
S82.11 Fracture of upper end of tibia (open)	0.000	0.622	0.378
S82.51 Fracture of medial malleolus (open)	0.000	0.626	0.374
S82.30 Fracture of lower end of tibia (closed)	0.000	0.635	0.365
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.639	0.361
S82.60 Fracture of lateral malleolus (closed)	0.000	0.643	0.357
M81.48 Drug-induced osteoporosis (Other)	0.000	0.652	0.348
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.652	0.348
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.652	0.348
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.652	0.348
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.652	0.348
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.652	0.348
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.652	0.348
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.652	0.348
S82.81 Fractures of other parts of lower leg (open)	0.000	0.655	0.345
S82.71 Multiple fractures of lower leg (open)	0.000	0.661	0.339
S82.41 Fracture of fibula alone (open)	0.000	0.663	0.337
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.664	0.336
M81.28 Osteoporosis of disuse (Other)	0.000	0.664	0.336
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.664	0.336
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.664	0.336
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.664	0.336
M81.24 Osteoporosis of disuse (Hand)	0.000	0.664	0.336
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.664	0.336
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.664	0.336
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.664	0.336
S82.2 Fracture of shaft of tibia	0.000	0.666	0.334
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.667	0.333
S52.21 Fracture of shaft of ulna (open)	0.001	0.670	0.329
S82.61 Fracture of lateral malleolus (open)	0.000	0.673	0.326
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.676	0.324
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.676	0.324
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.676	0.324
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.676	0.324
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.676	0.324
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.676	0.324
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.676	0.324
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.676	0.324
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.676	0.324
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.679	0.320
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.681	0.319
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.681	0.319
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.681	0.319
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.681	0.319
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.681	0.319
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.681	0.319
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.681	0.319
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.681	0.319
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.681	0.319
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.682	0.318
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.682	0.318
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.682	0.318
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.682	0.318
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.682	0.318
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.682	0.318
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.682	0.318
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.682	0.318
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.682	0.318
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.682	0.318
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.682	0.318
M81.58 Idiopathic osteoporosis (Other)	0.000	0.682	0.318
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.682	0.318
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.682	0.318
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.682	0.318
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.682	0.318
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.682	0.318
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.682	0.318
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.682	0.318
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.682	0.318
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.682	0.318
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.682	0.318
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.682	0.318
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.682	0.318
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.682	0.318
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.682	0.318
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.682	0.318
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.682	0.318
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.682	0.318
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.682	0.318
M81.89 Other osteoporosis (Site unspecified)	0.000	0.682	0.318
M81.88 Other osteoporosis (Other)	0.000	0.682	0.318
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.682	0.318
M81.86 Other osteoporosis (Lower leg)	0.000	0.682	0.318
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.682	0.318
M81.84 Other osteoporosis (Hand)	0.000	0.682	0.318
M81.83 Other osteoporosis (Forearm)	0.000	0.682	0.318
M81.82 Other osteoporosis (Upper arm)	0.000	0.682	0.318
M81.81 Other osteoporosis (Shoulder region)	0.000	0.682	0.318
M81.80 Other osteoporosis (Multiple sites)	0.000	0.682	0.318
S82.31 Fracture of lower end of tibia (open)	0.000	0.683	0.316
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.695	0.305
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.695	0.305
S52.00 Fracture of upper end of ulna (closed)	0.000	0.705	0.295
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.705	0.295
M80-M85 Disorders of bone density and structure	0.000	0.720	0.280
M84 Disorders of continuity of bone	0.000	0.735	0.265
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.740	0.260
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.753	0.247
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.760	0.240
S52.20 Fracture of shaft of ulna (closed)	0.001	0.772	0.227
S82.21 Fracture of shaft of tibia (open)	0.000	0.780	0.220
M83 Adult osteomalacia	0.000	0.794	0.206
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.795	0.205
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.796	0.204
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.806	0.194
M84.0 Malunion of fracture	0.000	0.809	0.191
M84.9 Disorder of continuity of bone, unspecified	0.000	0.810	0.190
M84.2 Delayed union of fracture	0.000	0.810	0.190
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.813	0.187
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.813	0.186
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.813	0.186
M84.3 Stress fracture, not elsewhere classified	0.000	0.814	0.186
S82.20 Fracture of shaft of tibia (closed)	0.000	0.820	0.180
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.821	0.179
S80-S89 Injuries to the knee and lower leg	0.000	0.821	0.179
M84.4 Pathological fracture, not elsewhere classified	0.000	0.822	0.178
M82 Osteoporosis in diseases classified elsewhere	0.001	0.832	0.168
M84.8 Other disorders of continuity of bone	0.000	0.838	0.162
M84.03 Malunion of fracture (Forearm)	0.000	0.846	0.154
M83.8 Other adult osteomalacia	0.000	0.849	0.150
M83.1 Senile osteomalacia	0.000	0.849	0.150
M83.9 Adult osteomalacia, unspecified	0.000	0.852	0.148
M83.5 Other drug-induced osteomalacia in adults	0.000	0.852	0.148
M83.4 Aluminum bone disease	0.000	0.852	0.148
M83.3 Adult osteomalacia due to malnutrition	0.000	0.852	0.148
M83.2 Adult osteomalacia due to malabsorption	0.000	0.852	0.148
M83.0 Puerperal osteomalacia	0.000	0.852	0.148
S89 Other and unspecified injuries of lower leg	0.000	0.853	0.147
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.853	0.147
M84.02 Malunion of fracture (Upper arm)	0.000	0.858	0.142
M84.01 Malunion of fracture (Shoulder region)	0.000	0.858	0.142
M80 Osteoporosis with pathological fracture	0.000	0.859	0.141
S86 Injury of muscle and tendon at lower leg level	0.000	0.859	0.140
M84.04 Malunion of fracture (Hand)	0.000	0.860	0.140
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.861	0.139
M84.09 Malunion of fracture (Site unspecified)	0.000	0.862	0.137
M84.00 Malunion of fracture (Multiple sites)	0.000	0.862	0.137
M84.29 Delayed union of fracture (Site unspecified)	0.000	0.863	0.136
M84.28 Delayed union of fracture (Other)	0.000	0.863	0.136
M84.27 Delayed union of fracture (Ankle and foot)	0.000	0.863	0.136
M84.26 Delayed union of fracture (Lower leg)	0.000	0.863	0.136
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.000	0.863	0.136
M84.24 Delayed union of fracture (Hand)	0.000	0.863	0.136
M84.23 Delayed union of fracture (Forearm)	0.000	0.863	0.136
M84.22 Delayed union of fracture (Upper arm)	0.000	0.863	0.136
M84.21 Delayed union of fracture (Shoulder region)	0.000	0.863	0.136
M84.20 Delayed union of fracture (Multiple sites)	0.000	0.863	0.136
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.000	0.863	0.136
M84.98 Disorder of continuity of bone, unspecified (Other)	0.000	0.863	0.136
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.000	0.863	0.136
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.000	0.863	0.136
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.000	0.863	0.136
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.000	0.863	0.136
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.000	0.863	0.136
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.000	0.863	0.136
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.000	0.863	0.136
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.000	0.863	0.136
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.000	0.867	0.133
M84.38 Stress fracture, not elsewhere classified (Other)	0.000	0.867	0.133
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.000	0.867	0.133
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.867	0.133
M84.34 Stress fracture, not elsewhere classified (Hand)	0.000	0.867	0.133
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.000	0.867	0.133
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.000	0.867	0.133
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.000	0.867	0.133
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.000	0.867	0.133
M85 Other disorders of bone density and structure	0.000	0.867	0.133
S62.60 Fracture of other finger (closed)	0.000	0.870	0.130
S50-S59 Injuries to the elbow and forearm	0.000	0.871	0.129
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.871	0.129
S88 Traumatic amputation of lower leg	0.000	0.871	0.128
S87 Crushing injury of lower leg	0.000	0.871	0.128
S85 Injury of blood vessels at lower leg level	0.000	0.871	0.128
S84 Injury of nerves at lower leg level	0.000	0.871	0.128
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.872	0.128
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.872	0.128
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.872	0.128
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.872	0.128
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.872	0.128
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.872	0.128
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.000	0.872	0.128
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.872	0.128
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.874	0.126
M84.08 Malunion of fracture (Other)	0.000	0.877	0.123
M82.8 Osteoporosis in other diseases classified elsewhere	0.001	0.879	0.120
M82.0 Osteoporosis in multiple myelomatosis	0.001	0.879	0.120
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.001	0.879	0.120
S81 Open wound of lower leg	0.000	0.881	0.119
S89.9 Unspecified injury of lower leg	0.000	0.881	0.119
M84.06 Malunion of fracture (Lower leg)	0.000	0.883	0.116
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.884	0.116
M84.89 Other disorders of continuity of bone (Site unspecified)	0.000	0.884	0.116
M84.88 Other disorders of continuity of bone (Other)	0.000	0.884	0.116
M84.86 Other disorders of continuity of bone (Lower leg)	0.000	0.884	0.116
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.000	0.884	0.116
M84.84 Other disorders of continuity of bone (Hand)	0.000	0.884	0.116
M84.82 Other disorders of continuity of bone (Upper arm)	0.000	0.884	0.116
M84.81 Other disorders of continuity of bone (Shoulder region)	0.000	0.884	0.116
M84.80 Other disorders of continuity of bone (Multiple sites)	0.000	0.884	0.116
M80.8 Other osteoporosis with pathological fracture	0.000	0.884	0.115
S00.8 Superficial injury of other parts of head	0.000	0.885	0.115
S89.8 Other specified injuries of lower leg	0.000	0.886	0.114
S00 Superficial injury of head	0.000	0.889	0.111
S00.1 Contusion of eyelid and periocular area	0.000	0.889	0.111
M83.12 Senile osteomalacia (Upper arm)	0.000	0.889	0.111
M83.80 Other adult osteomalacia (Multiple sites)	0.000	0.889	0.111
M83.19 Senile osteomalacia (Site unspecified)	0.000	0.892	0.108
M83.18 Senile osteomalacia (Other)	0.000	0.892	0.108
M83.17 Senile osteomalacia (Ankle and foot)	0.000	0.892	0.108
M83.16 Senile osteomalacia (Lower leg)	0.000	0.892	0.108
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.000	0.892	0.108
M83.14 Senile osteomalacia (Hand)	0.000	0.892	0.108
M83.13 Senile osteomalacia (Forearm)	0.000	0.892	0.108
M83.11 Senile osteomalacia (Shoulder region)	0.000	0.892	0.108
M83.10 Senile osteomalacia (Multiple sites)	0.000	0.892	0.108
M83.89 Other adult osteomalacia (Site unspecified)	0.000	0.892	0.108
M83.88 Other adult osteomalacia (Other)	0.000	0.892	0.108
M83.87 Other adult osteomalacia (Ankle and foot)	0.000	0.892	0.108
M83.86 Other adult osteomalacia (Lower leg)	0.000	0.892	0.108
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.000	0.892	0.108
M83.84 Other adult osteomalacia (Hand)	0.000	0.892	0.108
M83.83 Other adult osteomalacia (Forearm)	0.000	0.892	0.108
M83.82 Other adult osteomalacia (Upper arm)	0.000	0.892	0.108
M83.81 Other adult osteomalacia (Shoulder region)	0.000	0.892	0.108
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.893	0.107
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.893	0.107
M83.09 Puerperal osteomalacia (Site unspecified)	0.000	0.894	0.106
M83.08 Puerperal osteomalacia (Other)	0.000	0.894	0.106
M83.07 Puerperal osteomalacia (Ankle and foot)	0.000	0.894	0.106
M83.06 Puerperal osteomalacia (Lower leg)	0.000	0.894	0.106
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.000	0.894	0.106
M83.04 Puerperal osteomalacia (Hand)	0.000	0.894	0.106
M83.03 Puerperal osteomalacia (Forearm)	0.000	0.894	0.106
M83.02 Puerperal osteomalacia (Upper arm)	0.000	0.894	0.106
M83.01 Puerperal osteomalacia (Shoulder region)	0.000	0.894	0.106
M83.00 Puerperal osteomalacia (Multiple sites)	0.000	0.894	0.106
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.000	0.894	0.106
M83.28 Adult osteomalacia due to malabsorption (Other)	0.000	0.894	0.106
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.000	0.894	0.106
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.000	0.894	0.106
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.000	0.894	0.106
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.000	0.894	0.106
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.000	0.894	0.106
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.000	0.894	0.106
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.000	0.894	0.106
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.000	0.894	0.106
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.000	0.894	0.106
M83.38 Adult osteomalacia due to malnutrition (Other)	0.000	0.894	0.106
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.000	0.894	0.106
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.000	0.894	0.106
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.000	0.894	0.106
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.000	0.894	0.106
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.000	0.894	0.106
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.000	0.894	0.106
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.000	0.894	0.106
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.000	0.894	0.106
M83.49 Aluminium bone disease (Site unspecified)	0.000	0.894	0.106
M83.48 Aluminium bone disease (Other)	0.000	0.894	0.106
M83.47 Aluminium bone disease (Ankle and foot)	0.000	0.894	0.106
M83.46 Aluminium bone disease (Lower leg)	0.000	0.894	0.106
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.000	0.894	0.106
M83.44 Aluminium bone disease (Hand)	0.000	0.894	0.106
M83.43 Aluminium bone disease (Forearm)	0.000	0.894	0.106
M83.42 Aluminium bone disease (Upper arm)	0.000	0.894	0.106
M83.41 Aluminium bone disease (Shoulder region)	0.000	0.894	0.106
M83.40 Aluminium bone disease (Multiple sites)	0.000	0.894	0.106
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.000	0.894	0.106
M83.58 Other drug-induced osteomalacia in adults (Other)	0.000	0.894	0.106
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.000	0.894	0.106
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.000	0.894	0.106
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.000	0.894	0.106
M83.54 Other drug-induced osteomalacia in adults (Hand)	0.000	0.894	0.106
M83.53 Other drug-induced osteomalacia in adults (Forearm)	0.000	0.894	0.106
M83.52 Other drug-induced osteomalacia in adults (Upper arm)	0.000	0.894	0.106
M83.51 Other drug-induced osteomalacia in adults (Shoulder region)	0.000	0.894	0.106
M83.50 Other drug-induced osteomalacia in adults (Multiple sites)	0.000	0.894	0.106
M83.99 Adult osteomalacia, unspecified (Site unspecified)	0.000	0.894	0.106
M83.98 Adult osteomalacia, unspecified (Other)	0.000	0.894	0.106
M83.97 Adult osteomalacia, unspecified (Ankle and foot)	0.000	0.894	0.106
M83.96 Adult osteomalacia, unspecified (Lower leg)	0.000	0.894	0.106
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)	0.000	0.894	0.106
M83.94 Adult osteomalacia, unspecified (Hand)	0.000	0.894	0.106
M83.93 Adult osteomalacia, unspecified (Forearm)	0.000	0.894	0.106
M83.92 Adult osteomalacia, unspecified (Upper arm)	0.000	0.894	0.106
M83.91 Adult osteomalacia, unspecified (Shoulder region)	0.000	0.894	0.106
M83.90 Adult osteomalacia, unspecified (Multiple sites)	0.000	0.894	0.106
S89.7 Multiple injuries of lower leg	0.000	0.894	0.106
S89.1 Other specified injuries of lower leg	0.000	0.894	0.106
S89.0 Multiple injuries of lower leg	0.000	0.894	0.106
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.894	0.105
Z47 Other orthopaedic follow-up care	0.000	0.896	0.104
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.896	0.104
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.897	0.103
M85.6 Other cyst of bone	0.000	0.898	0.102
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.898	0.101
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.898	0.101
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.898	0.101
S86.0 Injury of Achilles tendon	0.000	0.899	0.101
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.899	0.101
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.899	0.101
S81.7 Multiple open wounds of lower leg	0.000	0.900	0.100
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.900	0.100
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.901	0.099
S00.0 Superficial injury of scalp	0.000	0.901	0.099
S59 Other and unspecified injuries of forearm	0.000	0.902	0.098
M80.88 Other osteoporosis with pathological fracture (Other)	0.000	0.903	0.097
M85.5 Aneurysmal bone cyst	0.000	0.904	0.095
M85.4 Solitary bone cyst	0.000	0.904	0.095
M85.3 Osteitis condensans	0.000	0.904	0.095
M85.1 Skeletal fluorosis	0.000	0.904	0.095
M85.9 Disorder of bone density and structure, unspecified	0.000	0.905	0.094
M85.2 Hyperostosis of skull	0.000	0.907	0.093
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.907	0.093
S58 Traumatic amputation of forearm	0.000	0.907	0.093
S57 Crushing injury of forearm	0.000	0.907	0.093
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.000	0.907	0.093
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.908	0.092
S84.8 Injury of other nerves at lower leg level	0.000	0.908	0.092
S84.7 Injury of multiple nerves at lower leg level	0.000	0.908	0.092
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.908	0.092
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.908	0.092
S84.0 Injury of tibial nerve at lower leg level	0.000	0.908	0.092
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.908	0.092
S85.8 Injury of other blood vessels at lower leg level	0.000	0.908	0.092
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.908	0.092
S85.5 Injury of popliteal vein	0.000	0.908	0.092
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.908	0.092
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.908	0.092
S85.2 Injury of peroneal artery	0.000	0.908	0.092
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.908	0.092
S85.0 Injury of popliteal artery	0.000	0.908	0.092
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.908	0.092
S87.0 Crushing injury of knee	0.000	0.908	0.092
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.908	0.092
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.908	0.092
S88.0 Traumatic amputation at knee level	0.000	0.908	0.092
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.909	0.091
S00.7 Multiple superficial injuries of head	0.000	0.909	0.091
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.910	0.089
S54 Injury of nerves at forearm level	0.000	0.911	0.089
S81.0 Open wound of knee	0.000	0.911	0.089
M82.1 Osteoporosis in endocrine disorders	0.002	0.911	0.087
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.001	0.913	0.086
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.001	0.913	0.086
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.001	0.913	0.086
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.001	0.913	0.086
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.001	0.913	0.086
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.001	0.913	0.086
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.001	0.913	0.086
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.001	0.913	0.086
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.001	0.913	0.086
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.001	0.913	0.086
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.001	0.913	0.086
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.001	0.913	0.086
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.001	0.913	0.086
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.001	0.913	0.086
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.001	0.913	0.086
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.001	0.913	0.086
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.001	0.913	0.086
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.001	0.913	0.086
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.001	0.913	0.086
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.001	0.913	0.086
S00.4 Superficial injury of ear	0.000	0.913	0.087
S56 Injury of muscle and tendon at forearm level	0.000	0.915	0.085
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.001	0.915	0.085
S55 Injury of blood vessels at forearm level	0.000	0.916	0.084
S83.7 Injury to multiple structures of knee	0.000	0.917	0.083
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.917	0.083
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.000	0.917	0.083
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.000	0.917	0.083
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.000	0.917	0.083
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.917	0.083
M80.84 Other osteoporosis with pathological fracture (Hand)	0.000	0.917	0.083
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.000	0.917	0.083
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.000	0.917	0.083
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.000	0.917	0.083
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.000	0.917	0.083
M85.0 Fibrous dysplasia (monostotic)	0.000	0.918	0.082
S00.3 Superficial injury of nose	0.000	0.918	0.082
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.920	0.080
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.920	0.080
M85.65 Other cyst of bone (Pelvic region and thigh)	0.000	0.921	0.079
S83.3 Tear of articular cartilage of knee, current	0.000	0.923	0.077
S83.1 Dislocation of knee	0.000	0.923	0.077
M85.67 Other cyst of bone (Ankle and foot)	0.000	0.924	0.076
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.924	0.076
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.924	0.076
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.924	0.076
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.924	0.076
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.924	0.076
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.924	0.076
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.924	0.076
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.924	0.076
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.924	0.076
S59.9 Unspecified injury of forearm	0.000	0.925	0.075
S00.5 Superficial injury of lip and oral cavity	0.000	0.926	0.074
M85.69 Other cyst of bone (Site unspecified)	0.000	0.926	0.073
M85.66 Other cyst of bone (Lower leg)	0.000	0.926	0.073
M85.64 Other cyst of bone (Hand)	0.000	0.926	0.073
M85.63 Other cyst of bone (Forearm)	0.000	0.926	0.073
M85.62 Other cyst of bone (Upper arm)	0.000	0.926	0.073
M85.61 Other cyst of bone (Shoulder region)	0.000	0.926	0.073
M85.60 Other cyst of bone (Multiple sites)	0.000	0.926	0.073
S00.9 Superficial injury of head, part unspecified	0.000	0.927	0.073
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.927	0.073
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.927	0.073
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.927	0.073
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.927	0.073
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.927	0.073
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.927	0.073
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.927	0.073
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.927	0.073
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.927	0.073
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.927	0.073
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.927	0.073
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.927	0.073
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.927	0.073
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.927	0.073
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.927	0.073
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.927	0.073
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.927	0.073
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.927	0.073
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.927	0.073
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.927	0.073
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.927	0.073
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.927	0.073
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.927	0.073
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.927	0.073
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.927	0.073
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.000	0.927	0.073
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.000	0.927	0.073
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.000	0.927	0.073
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.000	0.927	0.073

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations