TreeWAS – Variant ID: rs5745687

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	0.000	0.950	0.050
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.970	0.030
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.975	0.025
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.976	0.023
E05.8 Other thyrotoxicosis	0.000	0.978	0.022
E05.5 Thyroid crisis or storm	0.000	0.978	0.022
E05.4 Thyrotoxicosis factitia	0.000	0.978	0.022
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.978	0.022
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.978	0.022
K86 Other diseases of pancreas	0.008	0.992	0.000
K86.2 Cyst of pancreas	0.008	0.992	0.000
K86.3 Pseudocyst of pancreas	0.008	0.992	0.000
R59.0 Localised enlarged lymph nodes	0.007	0.993	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.007	0.993	0.000
K86.8 Other specified diseases of pancreas	0.007	0.993	0.000
K86.1 Other chronic pancreatitis	0.007	0.993	0.000
J93.9 Pneumothorax, unspecified	0.006	0.994	0.000
K86.9 Disease of pancreas, unspecified	0.006	0.994	0.000
H90 Conductive and sensorineural hearing loss	0.006	0.994	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.005	0.995	0.000
H90.2 Conductive hearing loss, unspecified	0.005	0.995	0.000
H90.5 Sensorineural hearing loss, unspecified	0.005	0.995	0.000
H91.9 Hearing loss, unspecified	0.005	0.995	0.000
R59.9 Enlarged lymph nodes, unspecified	0.005	0.995	0.000
R59 Enlarged lymph nodes	0.005	0.995	0.000
H90.0 Conductive hearing loss, bilateral	0.005	0.995	0.000
D86.9 Sarcoidosis, unspecified	0.004	0.996	0.000
N85.0 Endometrial glandular hyperplasia	0.004	0.996	0.000
H91 Other hearing loss	0.004	0.996	0.000
O20.0 Threatened abortion	0.004	0.996	0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.000	0.996	0.004
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.004	0.996	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.004	0.996	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.004	0.996	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.004	0.996	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.004	0.996	0.000
H90.3 Sensorineural hearing loss, bilateral	0.004	0.996	0.000
H90-H95 Other disorders of ear	0.004	0.996	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.004	0.996	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.004	0.996	0.000
E66.9 Obesity, unspecified	0.004	0.996	0.000
E66.8 Other obesity	0.004	0.996	0.000
E66 Obesity	0.004	0.996	0.000
H01.0 Blepharitis	0.004	0.996	0.000
Q61.0 Congenital single renal cyst	0.004	0.996	0.000
D86.0 Sarcoidosis of lung	0.004	0.996	0.000
D86 Sarcoidosis	0.003	0.997	0.000
K85.9 Acute pancreatitis, unspecified	0.003	0.997	0.000
H91.3 Deaf mutism, not elsewhere classified	0.003	0.997	0.000
H91.2 Sudden idiopathic hearing loss	0.003	0.997	0.000
H91.1 Presbycusis	0.003	0.997	0.000
H91.0 Ototoxic hearing loss	0.003	0.997	0.000
I20.9 Angina pectoris, unspecified	0.003	0.997	0.000
E66.0 Obesity due to excess calories	0.003	0.997	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.003	0.997	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.003	0.997	0.000
H92 Otalgia and effusion of ear	0.003	0.997	0.000
R59.1 Generalised enlarged lymph nodes	0.003	0.997	0.000
Q61 Cystic kidney disease	0.003	0.997	0.000
K85 Acute pancreatitis	0.003	0.997	0.000
D23.7 Skin of lower limb, including hip	0.000	0.997	0.003
H91.8 Other specified hearing loss	0.003	0.997	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.003	0.997	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.000	0.997	0.003
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.000	0.997	0.003
E66.1 Drug-induced obesity	0.003	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.003	0.997	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.003	0.997	0.000
M41.9 Scoliosis, unspecified	0.003	0.997	0.000
E00-E07 Disorders of thyroid gland	0.000	0.997	0.003
Q61.5 Medullary cystic kidney	0.003	0.997	0.000
Q61.9 Cystic kidney disease, unspecified	0.003	0.997	0.000
O20 Haemorrhage in early pregnancy	0.003	0.997	0.000
D86.3 Sarcoidosis of skin	0.003	0.997	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.003	0.997	0.000
K85.1 Biliary acute pancreatitis	0.003	0.997	0.000
Q60.0 Renal agenesis, unilateral	0.003	0.997	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.003	0.997	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.003	0.997	0.000
R06.8 Other and unspecified abnormalities of breathing	0.003	0.997	0.000
H92.1 Otorrhoea	0.003	0.997	0.000
H93 Other disorders of ear, not elsewhere classified	0.003	0.997	0.000
I24.8 Other forms of acute ischaemic heart disease	0.000	0.997	0.003
R14 Flatulence and related conditions	0.003	0.997	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.003	0.997	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.003	0.997	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.003	0.997	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.003	0.997	0.000
H92.0 Otalgia	0.003	0.997	0.000
D86.8 Sarcoidosis of other and combined sites	0.002	0.997	0.000
H92.2 Otorrhagia	0.002	0.997	0.000
K85.2 Alcohol-induced acute pancreatitis	0.002	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
Q61.8 Other cystic kidney diseases	0.002	0.997	0.000
Q61.4 Renal dysplasia	0.002	0.997	0.000
Q61.1 Polycystic kidney, infantile type	0.002	0.997	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.003	0.997	0.000
K85.8 Other acute pancreatitis	0.002	0.997	0.000
K85.3 Drug-induced acute pancreatitis	0.002	0.997	0.000
K85.0 Idiopathic acute pancreatitis	0.002	0.997	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.003	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.002	0.997	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.002	0.997	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.002	0.998	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
Z35.5 Supervision of elderly primigravida	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.002	0.998	0.000
K42 Umbilical hernia	0.002	0.998	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.002	0.998	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.002	0.998	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.002	0.998	0.000
Z01.5 Diagnostic skin and sensitisation tests	0.000	0.998	0.002
J93 Pneumothorax	0.002	0.998	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.002	0.998	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
H93.9 Disorder of ear, unspecified	0.002	0.998	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.998	0.002
E00 Congenital iodine-deficiency syndrome	0.000	0.998	0.002
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.998	0.002
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.998	0.002
J35.8 Other chronic diseases of tonsils and adenoids	0.002	0.998	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.002	0.998	0.000
E07 Other disorders of thyroid	0.000	0.998	0.002
D23.4 Skin of scalp and neck	0.000	0.998	0.002
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.002	0.998	0.000
W02.9 Unspecified place	0.002	0.998	0.000
H93.8 Other specified disorders of ear	0.002	0.998	0.000
H93.3 Disorders of acoustic nerve	0.002	0.998	0.000
H93.2 Other abnormal auditory perceptions	0.002	0.998	0.000
H93.0 Degenerative and vascular disorders of ear	0.002	0.998	0.000
H95.1 Other disorders following mastoidectomy	0.002	0.998	0.000
Q60.6 Potter's syndrome	0.002	0.998	0.000
Q60.5 Renal hypoplasia, unspecified	0.002	0.998	0.000
Q60.4 Renal hypoplasia, bilateral	0.002	0.998	0.000
Q60.3 Renal hypoplasia, unilateral	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.002	0.998	0.000
Q60.1 Renal agenesis, bilateral	0.002	0.998	0.000
Z73 Problems related to life-management difficulty	0.002	0.998	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.002	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.998	0.002
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
E06 Thyroiditis	0.000	0.998	0.002
H01 Other inflammation of eyelid	0.002	0.998	0.000
K81 Cholecystitis	0.002	0.998	0.000
N85.1 Endometrial adenomatous hyperplasia	0.002	0.998	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.998	0.002
J03.9 Acute tonsillitis, unspecified	0.000	0.998	0.002
Z35.8 Supervision of other high-risk pregnancies	0.002	0.998	0.000
M54.57 Low back pain (Lumbosacral region)	0.002	0.998	0.000
Q21.1 Atrial septal defect	0.002	0.998	0.000
H01.8 Other specified inflammation of eyelid	0.002	0.998	0.000
K42.1 Umbilical hernia with gangrene	0.002	0.998	0.000
J93.0 Spontaneous tension pneumothorax	0.002	0.998	0.000
K83.8 Other specified diseases of biliary tract	0.002	0.998	0.000
S61.1 Open wound of finger(s) with damage to nail	0.002	0.998	0.000
C91.1 Chronic lymphocytic leukaemia	0.002	0.998	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.998	0.002
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.998	0.002
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.998	0.002
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.998	0.002
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.998	0.002
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.998	0.002
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.998	0.002
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.998	0.002
O20.8 Other haemorrhage in early pregnancy	0.002	0.998	0.000
R60.0 Localised oedema	0.000	0.998	0.002
J93.1 Other spontaneous pneumothorax	0.002	0.998	0.000
N85.6 Intra-uterine synechiae	0.002	0.998	0.000
N85 Other noninflammatory disorders of uterus, except cervix	0.002	0.998	0.000
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
A87.9 Viral meningitis, unspecified	0.002	0.998	0.000
K81.1 Chronic cholecystitis	0.002	0.998	0.000
Z72.0 Tobacco use	0.002	0.998	0.000
G50.0 Trigeminal neuralgia	0.000	0.998	0.002
O86.0 Infection of obstetric surgical wound	0.002	0.998	0.000
K55.2 Angiodysplasia of colon	0.000	0.998	0.002
E07.1 Dyshormogenetic goitre	0.000	0.998	0.002
E07.0 Hypersecretion of calcitonin	0.000	0.998	0.002
Z83.7 Family history of diseases of the digestive system	0.000	0.998	0.002
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.002	0.998	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.002	0.998	0.000
C81.9 Hodgkin's disease, unspecified	0.002	0.998	0.000
E06.9 Thyroiditis, unspecified	0.000	0.998	0.002
K87.1 Disorders of pancreas in diseases classified elsewhere	0.002	0.998	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.002	0.998	0.000
Z73.8 Other problems related to life-management difficulty	0.002	0.998	0.000
Z73.6 Limitation of activities due to disability	0.002	0.998	0.000
Z73.5 Social role conflict, not elsewhere classified	0.002	0.998	0.000
Z73.4 Inadequate social skills, not elsewhere classified	0.002	0.998	0.000
Z73.2 Lack of relaxation and leisure	0.002	0.998	0.000
Z73.1 Accentuation of personality traits	0.002	0.998	0.000
Z73.0 Burn-out	0.002	0.998	0.000
Q62.8 Other congenital malformations of ureter	0.002	0.998	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.002	0.998	0.000
Q62.6 Malposition of ureter	0.002	0.998	0.000
Q62.5 Duplication of ureter	0.002	0.998	0.000
Q62.4 Agenesis of ureter	0.002	0.998	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.002	0.998	0.000
Q62.2 Congenital megaloureter	0.002	0.998	0.000
Q62.1 Atresia and stenosis of ureter	0.002	0.998	0.000
Q62.0 Congenital hydronephrosis	0.002	0.998	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.002	0.998	0.000
Q64.8 Other specified congenital malformations of urinary system	0.002	0.998	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.002	0.998	0.000
Q64.6 Congenital diverticulum of bladder	0.002	0.998	0.000
Q64.5 Congenital absence of bladder and urethra	0.002	0.998	0.000
Q64.4 Malformation of urachus	0.002	0.998	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.998	0.000
Q64.2 Congenital posterior urethral valves	0.002	0.998	0.000
Q64.1 Exstrophy of urinary bladder	0.002	0.998	0.000
Q64.0 Epispadias	0.002	0.998	0.000
K83 Other diseases of biliary tract	0.002	0.998	0.000
D05.1 Intraductal carcinoma in situ	0.002	0.998	0.000
E06.5 Other chronic thyroiditis	0.000	0.998	0.002
E06.4 Drug-induced thyroiditis	0.000	0.998	0.002
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.998	0.002
E06.1 Subacute thyroiditis	0.000	0.998	0.002
E06.0 Acute thyroiditis	0.000	0.998	0.002
E07.8 Other specified disorders of thyroid	0.000	0.998	0.002
S61.8 Open wound of other parts of wrist and hand	0.002	0.998	0.000
Z35 Supervision of high-risk pregnancy	0.002	0.998	0.000
G93.3 Postviral fatigue syndrome	0.000	0.998	0.002
H01.9 Inflammation of eyelid, unspecified	0.002	0.998	0.000
H01.1 Non-infectious dermatoses of eyelid	0.002	0.998	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.002	0.998	0.000
K81.8 Other cholecystitis	0.002	0.998	0.000
Z01.4 Gynaecological examination (general)(routine)	0.000	0.998	0.002
K81.0 Acute cholecystitis	0.002	0.998	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.002	0.998	0.000
N85.9 Noninflammatory disorder of uterus, unspecified	0.002	0.998	0.000
O86 Other puerperal infections	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.998	0.002
H52.1 Myopia	0.002	0.998	0.000
J38.1 Polyp of vocal cord and larynx	0.000	0.998	0.002
O86.4 Pyrexia of unknown origin following delivery	0.002	0.998	0.000
S68 Traumatic amputation of wrist and hand	0.002	0.998	0.000
E65-E68 Obesity and other hyperalimentation	0.002	0.998	0.000
J93.8 Other pneumothorax	0.001	0.998	0.000
O86.1 Other infection of genital tract following delivery	0.002	0.998	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.002	0.998	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.002	0.998	0.000
M41 Scoliosis	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.002	0.998	0.000
K76.8 Other specified diseases of liver	0.002	0.998	0.000
N85.7 Haematometra	0.002	0.998	0.000
N85.5 Inversion of uterus	0.002	0.998	0.000
N85.3 Subinvolution of uterus	0.002	0.998	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.001	0.998	0.000
Q63.8 Other specified congenital malformations of kidney	0.001	0.998	0.000
Q63.3 Hyperplastic and giant kidney	0.001	0.998	0.000
Q63.2 Ectopic kidney	0.001	0.998	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.001	0.998	0.000
Y84.6 Urinary catheterisation	0.002	0.998	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.002	0.998	0.000
K55.0 Acute vascular disorders of intestine	0.000	0.998	0.002
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
O86.2 Urinary tract infection following delivery	0.002	0.998	0.000
S61 Open wound of wrist and hand	0.002	0.998	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.001	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.001	0.998	0.000
Q21.4 Aortopulmonary septal defect	0.001	0.998	0.000
Q21.3 Tetralogy of Fallot	0.001	0.998	0.000
Q21.2 Atrioventricular septal defect	0.001	0.998	0.000
Q21.0 Ventricular septal defect	0.001	0.998	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.002	0.998	0.000
D23.1 Skin of eyelid, including canthus	0.000	0.998	0.002
Q25.1 Coarctation of aorta	0.001	0.998	0.000
Z73.3 Stress, not elsewhere classified	0.001	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
K83.5 Biliary cyst	0.001	0.998	0.000
K83.4 Spasm of sphincter of Oddi	0.001	0.998	0.000
K83.3 Fistula of bile duct	0.001	0.998	0.000
K83.2 Perforation of bile duct	0.001	0.998	0.000
Z01.6 Radiological examination, not elsewhere classified	0.000	0.998	0.002
E03 Other hypothyroidism	0.000	0.998	0.001
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.001	0.998	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.001	0.998	0.000
Z35.6 Supervision of very young primigravida	0.001	0.998	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.001	0.998	0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.000	0.998	0.002
D03.3 Melanoma in situ of other and unspecified parts of face	0.002	0.998	0.000
N76.0 Acute vaginitis	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.001	0.998	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.001	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.001	0.998	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.001	0.998	0.000
O28 Abnormal findings on antenatal screening of mother	0.001	0.998	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.001	0.998	0.000
O86.8 Other specified puerperal infections	0.001	0.998	0.000
O86.3 Other genito-urinary tract infections following delivery	0.001	0.998	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.001	0.998	0.000
Q26 Congenital malformations of great veins	0.001	0.998	0.000
Q24 Other congenital malformations of heart	0.001	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.001	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.001	0.998	0.000
Q66 Congenital deformities of feet	0.001	0.998	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.998	0.001
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.001	0.998	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.001	0.998	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.001	0.998	0.000
S68.4 Traumatic amputation of hand at wrist level	0.001	0.998	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.001	0.998	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.001	0.998	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.001	0.998	0.000
E03.8 Other specified hypothyroidism	0.000	0.998	0.001
E06.3 Autoimmune thyroiditis	0.000	0.998	0.001
S68.0 Traumatic amputation of thumb (complete)(partial)	0.001	0.998	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.001	0.998	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.001	0.998	0.000
E67 Other hyperalimentation	0.001	0.998	0.000
E68 Sequelae of hyperalimentation	0.001	0.998	0.000
E65 Localised adiposity	0.001	0.998	0.000
M89 Other disorders of bone	0.001	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.001	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.001	0.999	0.000
M41.8 Other forms of scoliosis	0.001	0.999	0.000
M41.5 Other secondary scoliosis	0.001	0.999	0.000
M41.4 Neuromuscular scoliosis	0.001	0.999	0.000
M41.3 Thoracogenic scoliosis	0.001	0.999	0.000
M41.2 Other idiopathic scoliosis	0.001	0.999	0.000
M41.1 Juvenile idiopathic scoliosis	0.001	0.999	0.000
M41.0 Infantile idiopathic scoliosis	0.001	0.999	0.000
M89.0 Algoneurodystrophy	0.001	0.999	0.000
Y83.9 Surgical procedure, unspecified	0.001	0.999	0.000
I26 Pulmonary embolism	0.001	0.999	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.001	0.999	0.000
Q35-Q37 Cleft lip and cleft palate	0.001	0.999	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.001	0.999	0.000
K83.9 Disease of biliary tract, unspecified	0.001	0.999	0.000
M89.8 Other specified disorders of bone	0.001	0.999	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.001	0.999	0.000
Q25.8 Other congenital malformations of great arteries	0.001	0.999	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.001	0.999	0.000
Q25.6 Stenosis of pulmonary artery	0.001	0.999	0.000
Q25.5 Atresia of pulmonary artery	0.001	0.999	0.000
Q25.4 Other congenital malformations of aorta	0.001	0.999	0.000
Q25.3 Stenosis of aorta	0.001	0.999	0.000
Q25.2 Atresia of aorta	0.001	0.999	0.000
Q25.0 Patent ductus arteriosus	0.001	0.999	0.000
Q66.8 Other congenital deformities of feet	0.001	0.999	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.001	0.999	0.000
Q80-Q89 Other congenital malformations	0.001	0.999	0.000
Q00-Q07 Congenital malformations of the nervous system	0.001	0.999	0.000
D03.5 Melanoma in situ of trunk	0.001	0.999	0.000
M89.5 Osteolysis	0.001	0.999	0.000
N85.2 Hypertrophy of uterus	0.001	0.999	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.001	0.999	0.000
O24 Diabetes mellitus in pregnancy	0.001	0.999	0.000
Q27 Other congenital malformations of peripheral vascular system	0.001	0.999	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.001	0.999	0.000
C84.0 Mycosis fungoides	0.001	0.999	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.001	0.999	0.000
C81 Hodgkin's disease	0.001	0.999	0.000
Q78 Other osteochondrodysplasias	0.001	0.999	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.999	0.000
Q75 Other congenital malformations of skull and face bones	0.001	0.999	0.000
Q74 Other congenital malformations of limb(s)	0.001	0.999	0.000
Q73 Reduction defects of unspecified limb	0.001	0.999	0.000
Q72 Reduction defects of lower limb	0.001	0.999	0.000
Q71 Reduction defects of upper limb	0.001	0.999	0.000
Q70 Syndactyly	0.001	0.999	0.000
Q69 Polydactyly	0.001	0.999	0.000
Q68 Other congenital musculoskeletal deformities	0.001	0.999	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.001	0.999	0.000
E03.5 Myxoedema coma	0.000	0.999	0.001
E03.4 Atrophy of thyroid (acquired)	0.000	0.999	0.001
E03.3 Postinfectious hypothyroidism	0.000	0.999	0.001
E03.1 Congenital hypothyroidism without goitre	0.000	0.999	0.001
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.999	0.001
M88.9 Paget's disease of bone, unspecified	0.001	0.999	0.000
Q23.1 Congenital insufficiency of aortic valve	0.001	0.999	0.000
Q63.0 Accessory kidney	0.001	0.999	0.000
C91 Lymphoid leukaemia	0.001	0.999	0.000
D03 Melanoma in situ	0.001	0.999	0.000
Q43 Other congenital malformations of intestine	0.001	0.999	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.001	0.999	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.001	0.999	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.001	0.999	0.000
Q23.4 Hypoplastic left heart syndrome	0.001	0.999	0.000
Q23.3 Congenital mitral insufficiency	0.001	0.999	0.000
Q23.2 Congenital mitral stenosis	0.001	0.999	0.000
Q23.0 Congenital stenosis of aortic valve	0.001	0.999	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.001	0.999	0.000
Q76.8 Other congenital malformations of bony thorax	0.001	0.999	0.000
Q76.7 Congenital malformation of sternum	0.001	0.999	0.000
Q76.6 Other congenital malformations of ribs	0.001	0.999	0.000
Q76.5 Cervical rib	0.001	0.999	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.001	0.999	0.000
Q76.2 Congenital spondylolisthesis	0.001	0.999	0.000
Q76.1 Klippel-Feil syndrome	0.001	0.999	0.000
Z01.9 Special examination, unspecified	0.000	0.999	0.001
Z01.7 Laboratory examination	0.000	0.999	0.001
Z01.3 Examination of blood pressure	0.000	0.999	0.001
Z01.1 Examination of ears and hearing	0.000	0.999	0.001
Z01.0 Examination of eyes and vision	0.000	0.999	0.001
Q07 Other congenital malformations of nervous system	0.001	0.999	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.001	0.999	0.000
M89.98 Disorder of bone, unspecified (Other)	0.001	0.999	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.001	0.999	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.001	0.999	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.001	0.999	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.001	0.999	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.001	0.999	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.001	0.999	0.000
C81.1 Nodular sclerosis	0.001	0.999	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.001	0.999	0.000
H93.1 Tinnitus	0.001	0.999	0.000
L81.9 Disorder of pigmentation, unspecified	0.001	0.999	0.000
Q76.0 Spina bifida occulta	0.001	0.999	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.001	0.999	0.000
O29 Complications of anaesthesia during pregnancy	0.001	0.999	0.000
O22 Venous complications in pregnancy	0.001	0.999	0.000
O25 Malnutrition in pregnancy	0.001	0.999	0.000
Q28 Other congenital malformations of circulatory system	0.001	0.999	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.001	0.999	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.999	0.001
M89.86 Other specified disorders of bone (Lower leg)	0.001	0.999	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.001	0.999	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.001	0.999	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.001	0.999	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.001	0.999	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.001	0.999	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.001	0.999	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.001	0.999	0.000
Q07.0 Arnold-Chiari syndrome	0.001	0.999	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.001	0.999	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.001	0.999	0.000
Q20.6 Isomerism of atrial appendages	0.001	0.999	0.000
Q20.5 Discordant atrioventricular connexion	0.001	0.999	0.000
Q20.4 Double inlet ventricle	0.001	0.999	0.000
Q20.3 Discordant ventriculoarterial connexion	0.001	0.999	0.000
Q20.2 Double outlet left ventricle	0.001	0.999	0.000
Q20.1 Double outlet right ventricle	0.001	0.999	0.000
Q20.0 Common arterial trunk	0.001	0.999	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.001	0.999	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.001	0.999	0.000
Q22.6 Hypoplastic right heart syndrome	0.001	0.999	0.000
Q22.5 Ebstein's anomaly	0.001	0.999	0.000
Q22.4 Congenital tricuspid stenosis	0.001	0.999	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.001	0.999	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.001	0.999	0.000
Q22.1 Congenital pulmonary valve stenosis	0.001	0.999	0.000
Q22.0 Pulmonary valve atresia	0.001	0.999	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.001	0.999	0.000
Q24.6 Congenital heart block	0.001	0.999	0.000
Q24.5 Malformation of coronary vessels	0.001	0.999	0.000
Q24.4 Congenital subaortic stenosis	0.001	0.999	0.000
Q24.3 Pulmonary infundibular stenosis	0.001	0.999	0.000
Q24.2 Cor triatriatum	0.001	0.999	0.000
Q24.1 Levocardia	0.001	0.999	0.000
Q24.0 Dextrocardia	0.001	0.999	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.001	0.999	0.000
Q26.8 Other congenital malformations of great veins	0.001	0.999	0.000
Q26.6 Portal vein-hepatic artery fistula	0.001	0.999	0.000
Q26.5 Anomalous portal venous connexion	0.001	0.999	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.001	0.999	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.001	0.999	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.001	0.999	0.000
Q26.1 Persistent left superior vena cava	0.001	0.999	0.000
Q26.0 Congenital stenosis of vena cava	0.001	0.999	0.000
Q66.9 Congenital deformity of feet, unspecified	0.001	0.999	0.000
Q66.7 Pes cavus	0.001	0.999	0.000
Q66.6 Other congenital valgus deformities of feet	0.001	0.999	0.000
Q66.5 Congenital pes planus	0.001	0.999	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.999	0.000
Q66.3 Other congenital varus deformities of feet	0.001	0.999	0.000
Q66.2 Metatarsus varus	0.001	0.999	0.000
Q66.1 Talipes calcaneovarus	0.001	0.999	0.000
Q66.0 Talipes equinovarus	0.001	0.999	0.000
E67.8 Other specified hyperalimentation	0.001	0.999	0.000
E67.3 Hypervitaminosis D	0.001	0.999	0.000
E67.2 Megavitamin-B6 syndrome	0.001	0.999	0.000
E67.1 Hypercarotenaemia	0.001	0.999	0.000
E67.0 Hypervitaminosis A	0.001	0.999	0.000
M89.6 Osteopathy after poliomyelitis	0.001	0.999	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.001	0.999	0.000
M89.3 Hypertrophy of bone	0.001	0.999	0.000
M89.2 Other disorders of bone development and growth	0.001	0.999	0.000
M89.1 Epiphyseal arrest	0.001	0.999	0.000
Q24.8 Other specified congenital malformations of heart	0.001	0.999	0.000
S69.9 Unspecified injury of wrist and hand	0.001	0.999	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.001	0.999	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.001	0.999	0.000
Q45 Other congenital malformations of digestive system	0.001	0.999	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.001	0.999	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.001	0.999	0.000
Q40 Other congenital malformations of upper alimentary tract	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations