TreeWAS – Variant ID: rs5751452

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
M25 Other joint disorders, not elsewhere classified	0.308	0.692
M25.7 Osteophyte	0.305	0.695
M25.5 Pain in joint	0.298	0.702
M25.77 Osteophyte (Ankle and foot)	0.292	0.708
M25.4 Effusion of joint	0.291	0.709
M25.46 Effusion of joint (Lower leg)	0.281	0.719
M20-M25 Other joint disorders	0.281	0.719
M25.51 Pain in joint (Shoulder region)	0.280	0.720
M25.75 Osteophyte (Pelvic region and thigh)	0.278	0.722
M50-M54 Other dorsopathies	0.273	0.727
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.272	0.728
M25.56 Pain in joint (Lower leg)	0.271	0.729
M51 Other intervertebral disk disorders	0.271	0.729
M65-M68 Disorders of synovium and tendon	0.263	0.737
M65 Synovitis and tenosynovitis	0.260	0.740
M51.2 Other specified intervertebral disk displacement	0.258	0.742
M65.3 Trigger finger	0.257	0.743
M65.34 Trigger finger-Hand	0.256	0.744
M25.58 Pain in joint (Other)	0.251	0.749
M25.53 Pain in joint (Forearm)	0.251	0.749
M25.73 Osteophyte (Forearm)	0.251	0.749
M25.78 Osteophyte (Other)	0.243	0.757
M25.50 Pain in joint (Multiple sites)	0.241	0.758
M21 Other acquired deformities of limbs	0.241	0.759
M51.9 Intervertebral disk disorder, unspecified	0.241	0.759
M25.71 Osteophyte (Shoulder region)	0.232	0.767
M35 Other systemic involvement of connective tissue	0.232	0.768
M50 Cervical disk disorders	0.226	0.774
M60-M63 Disorders of muscles	0.225	0.775
M53 Other dorsopathies, not elsewhere classified	0.224	0.776
M25.3 Other instability of joint	0.223	0.777
M25.76 Osteophyte (Lower leg)	0.222	0.777
M80-M85 Disorders of bone density and structure	0.221	0.779
M25.2 Flail joint	0.221	0.779
M25.1 Fistula of joint	0.221	0.779
M25.79 Osteophyte (Site unspecified)	0.219	0.781
M25.70 Osteophyte (Multiple sites)	0.219	0.781
M66 Spontaneous rupture of synovium and tendon	0.217	0.783
M86-M90 Other osteopathies	0.216	0.784
M65.1 Other infective (teno)synovitis	0.214	0.786
M25.54 Pain in joint (Hand)	0.212	0.787
M50.3 Other cervical disk degeneration	0.209	0.791
M25.49 Effusion of joint (Site unspecified)	0.208	0.791
M25.48 Effusion of joint (Other)	0.208	0.791
M25.44 Effusion of joint (Hand)	0.208	0.791
M25.43 Effusion of joint (Forearm)	0.208	0.791
M25.42 Effusion of joint (Upper arm)	0.208	0.791
M25.41 Effusion of joint (Shoulder region)	0.208	0.791
M25.40 Effusion of joint (Multiple sites)	0.208	0.791
M25.0 Haemarthrosis	0.208	0.791
M51.4 Schmorl's nodes	0.208	0.791
M32 Systemic lupus erythematosus	0.208	0.792
M51.8 Other specified intervertebral disk disorders	0.207	0.793
M25.9 Joint disorder, unspecified	0.205	0.794
M21.4 Flat foot [pes planus] (acquired)	0.205	0.795
M25.45 Effusion of joint (Pelvic region and thigh)	0.204	0.796
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.202	0.798
M33 Dermatopolymyositis	0.202	0.798
M30 Polyarteritis nodosa and related conditions	0.202	0.798
M54 Dorsalgia	0.201	0.799
M25.59 Pain in joint (Site unspecified)	0.201	0.799
M25.8 Other specified joint disorders	0.200	0.800
M21.2 Flexion deformity	0.200	0.800
M35.7 Hypermobility syndrome	0.199	0.801
M34 Systemic sclerosis	0.197	0.803
M21.6 Other acquired deformities of ankle and foot	0.196	0.804
M51.3 Other specified intervertebral disk degeneration	0.194	0.806
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.194	0.806
M25.47 Effusion of joint (Ankle and foot)	0.192	0.808
M62 Other disorders of muscle	0.191	0.809
M91-M94 Chondropathies	0.190	0.810
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.189	0.811
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.189	0.811
M25.6 Stiffness of joint, not elsewhere classified	0.188	0.812
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.188	0.812
M00-M03 Infectious arthropathies	0.187	0.813
M24 Other specific joint derangements	0.187	0.813
M89 Other disorders of bone	0.187	0.813
M25.72 Osteophyte (Upper arm)	0.186	0.814
M65.2 Calcific tendinitis	0.186	0.814
M65.0 Abscess of tendon sheath	0.186	0.814
M65.39 Trigger finger-Site unspec	0.184	0.816
M65.38 Trigger finger-Other	0.184	0.816
M65.37 Trigger finger-Ankle/foot	0.184	0.816
M65.36 Trigger finger-Lower leg	0.184	0.816
M65.35 Trigger finger-Pelvic/thigh	0.184	0.816
M65.33 Trigger finger-Forearm	0.184	0.816
M65.32 Trigger finger-Upper arm	0.184	0.816
M65.31 Trigger finger-Shldr region	0.184	0.816
M65.30 Trigger finger-Mult sites	0.184	0.816
M65.8 Other synovitis and tenosynovitis	0.183	0.817
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.183	0.817
M35.3 Polymyalgia rheumatica	0.182	0.818
M66.2 Spontaneous rupture of extensor tendons	0.181	0.818
M65.4 Radial styloid tenosynovitis [de Quervain]	0.181	0.819
M65.14 Other infective (teno)synovitis (Hand)	0.181	0.819
M80 Osteoporosis with pathological fracture	0.179	0.821
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.179	0.821
M23 Internal derangement of knee	0.177	0.823
M25.52 Pain in joint (Upper arm)	0.176	0.824
M65.9 Synovitis and tenosynovitis, unspecified	0.175	0.825
M35.1 Other overlap syndromes	0.174	0.826
M21.9 Acquired deformity of limb, unspecified	0.173	0.827
M21.8 Other specified acquired deformities of limbs	0.173	0.827
M21.7 Unequal limb length (acquired)	0.173	0.827
M40-M43 Deforming dorsopathies	0.172	0.828
M21.3 Wrist or foot drop (acquired)	0.172	0.828
M50.2 Other cervical disk displacement	0.172	0.828
M22 Disorders of patella	0.171	0.829
M54.1 Radiculopathy	0.170	0.830
M90 Osteopathies in diseases classified elsewhere	0.168	0.831
M21.27 Flexion deformity (Ankle and foot)	0.168	0.832
M89.9 Disorder of bone, unspecified	0.168	0.832
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.167	0.833
M84 Disorders of continuity of bone	0.167	0.833
M35.9 Systemic involvement of connective tissue, unspecified	0.166	0.834
M35.8 Other specified systemic involvement of connective tissue	0.166	0.834
M35.6 Relapsing panniculitis [Weber-Christian]	0.166	0.834
M35.5 Multifocal fibrosclerosis	0.166	0.834
M35.4 Diffuse (eosinophilic) fasciitis	0.166	0.834
M35.2 Behcet's disease	0.166	0.834
M62.8 Other specified disorders of muscle	0.166	0.834
M25.37 Other instability of joint (Ankle and foot)	0.166	0.834
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.164	0.836
M25.81 Other specified joint disorders (Shoulder region)	0.164	0.836
M05-M14 Inflammatory polyarthropathies	0.163	0.837
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.163	0.837
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.162	0.837
M50.9 Cervical disk disorder, unspecified	0.162	0.838
M50.8 Other cervical disk disorders	0.162	0.838
M85 Other disorders of bone density and structure	0.162	0.838
M21.0 Valgus deformity, not elsewhere classified	0.161	0.838
M63 Disorders of muscle in diseases classified elsewhere	0.161	0.839
M61 Calcification and ossification of muscle	0.161	0.839
M60 Myositis	0.161	0.839
M23.8 Other internal derangements of knee	0.161	0.839
M25.74 Osteophyte (Hand)	0.161	0.839
M53.9 Dorsopathy, unspecified	0.160	0.839
M53.8 Other specified dorsopathies	0.160	0.839
M53.2 Spinal instabilities	0.160	0.839
M53.1 Cervicobrachial syndrome	0.160	0.839
M53.0 Cervicocranial syndrome	0.160	0.839
M25.39 Other instability of joint (Site unspecified)	0.160	0.840
M25.38 Other instability of joint (Other)	0.160	0.840
M25.36 Other instability of joint (Lower leg)	0.160	0.840
M25.35 Other instability of joint (Pelvic region and thigh)	0.160	0.840
M25.34 Other instability of joint (Hand)	0.160	0.840
M25.33 Other instability of joint (Forearm)	0.160	0.840
M25.32 Other instability of joint (Upper arm)	0.160	0.840
M25.30 Other instability of joint (Multiple sites)	0.160	0.840
M81 Osteoporosis without pathological fracture	0.160	0.840
M83 Adult osteomalacia	0.159	0.841
M66.0 Rupture of popliteal cyst	0.159	0.841
M25.19 Fistula of joint (Site unspecified)	0.159	0.841
M25.18 Fistula of joint (Other)	0.159	0.841
M25.17 Fistula of joint (Ankle and foot)	0.159	0.841
M25.16 Fistula of joint (Lower leg)	0.159	0.841
M25.15 Fistula of joint (Pelvic region and thigh)	0.159	0.841
M25.14 Fistula of joint (Hand)	0.159	0.841
M25.13 Fistula of joint (Forearm)	0.159	0.841
M25.12 Fistula of joint (Upper arm)	0.159	0.841
M25.11 Fistula of joint (Shoulder region)	0.159	0.841
M25.10 Fistula of joint (Multiple sites)	0.159	0.841
M25.29 Flail joint (Site unspecified)	0.159	0.841
M25.28 Flail joint (Other)	0.159	0.841
M25.27 Flail joint (Ankle and foot)	0.159	0.841
M25.26 Flail joint (Lower leg)	0.159	0.841
M25.25 Flail joint (Pelvic region and thigh)	0.159	0.841
M25.24 Flail joint (Hand)	0.159	0.841
M25.23 Flail joint (Forearm)	0.159	0.841
M25.22 Flail joint (Upper arm)	0.159	0.841
M25.21 Flail joint (Shoulder region)	0.159	0.841
M25.20 Flail joint (Multiple sites)	0.159	0.841
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.156	0.844
M32.1 Systemic lupus erythematosus with organ or system involvement	0.155	0.844
M66.5 Spontaneous rupture of unspecified tendon	0.155	0.844
M66.4 Spontaneous rupture of other tendons	0.155	0.844
M66.3 Spontaneous rupture of flexor tendons	0.155	0.844
M66.1 Rupture of synovium	0.155	0.844
M82 Osteoporosis in diseases classified elsewhere	0.155	0.845
M54.2 Cervicalgia	0.155	0.845
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.155	0.845
M25.31 Other instability of joint (Shoulder region)	0.154	0.845
M54.6 Pain in thoracic spine	0.154	0.846
M65.19 Other infective (teno)synovitis (Site unspecified)	0.153	0.846
M65.18 Other infective (teno)synovitis (Other)	0.153	0.846
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.153	0.846
M65.16 Other infective (teno)synovitis (Lower leg)	0.153	0.846
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)	0.153	0.846
M65.13 Other infective (teno)synovitis (Forearm)	0.153	0.846
M65.12 Other infective (teno)synovitis (Upper arm)	0.153	0.846
M65.11 Other infective (teno)synovitis (Shoulder region)	0.153	0.846
M65.10 Other infective (teno)synovitis (Multiple sites)	0.153	0.846
M86 Osteomyelitis	0.153	0.847
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.152	0.848
M25.09 Haemarthrosis (Site unspecified)	0.150	0.850
M25.08 Haemarthrosis (Other)	0.150	0.850
M25.07 Haemarthrosis (Ankle and foot)	0.150	0.850
M25.05 Haemarthrosis (Pelvic region and thigh)	0.150	0.850
M25.04 Haemarthrosis (Hand)	0.150	0.850
M25.03 Haemarthrosis (Forearm)	0.150	0.850
M25.02 Haemarthrosis (Upper arm)	0.150	0.850
M25.01 Haemarthrosis (Shoulder region)	0.150	0.850
M25.00 Haemarthrosis (Multiple sites)	0.150	0.850
M31 Other necrotising vasculopathies	0.150	0.850
M32.9 Systemic lupus erythematosus, unspecified	0.149	0.851
M32.8 Other forms of systemic lupus erythematosus	0.149	0.851
M32.0 Drug-induced systemic lupus erythematosus	0.149	0.851
M25.99 Joint disorder, unspecified (Site unspecified)	0.147	0.852
M25.98 Joint disorder, unspecified (Other)	0.147	0.852
M25.97 Joint disorder, unspecified (Ankle and foot)	0.147	0.852
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.147	0.852
M25.94 Joint disorder, unspecified (Hand)	0.147	0.852
M25.93 Joint disorder, unspecified (Forearm)	0.147	0.852
M25.92 Joint disorder, unspecified (Upper arm)	0.147	0.852
M25.91 Joint disorder, unspecified (Shoulder region)	0.147	0.852
M25.90 Joint disorder, unspecified (Multiple sites)	0.147	0.852
M21.26 Flexion deformity (Lower leg)	0.147	0.852
M34.8 Other forms of systemic sclerosis	0.147	0.853
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.147	0.853
M21.48 Flat foot [pes planus] (acquired)-Other	0.147	0.853
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.147	0.853
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.147	0.853
M21.44 Flat foot [pes planus] (acquired)-Hand	0.147	0.853
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.147	0.853
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.147	0.853
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.147	0.853
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.147	0.853
M23.5 Chronic instability of knee	0.146	0.854
M54.16 Radiculopathy (Lumbar region)	0.146	0.854
M24.2 Disorder of ligament	0.145	0.855
M30.8 Other conditions related to polyarteritis nodosa	0.145	0.855
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.145	0.855
M30.2 Juvenile polyarteritis	0.145	0.855
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.145	0.855
M30.0 Polyarteritis nodosa	0.145	0.855
M33.9 Dermatopolymyositis, unspecified	0.145	0.855
M33.2 Polymyositis	0.145	0.855
M33.1 Other dermatomyositis	0.145	0.855
M33.0 Juvenile dermatomyositis	0.145	0.855
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.145	0.855
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.145	0.855
M36.3 Arthropathy in other blood disorders	0.145	0.855
M36.2 Haemophilic arthropathy	0.145	0.855
M36.1 Arthropathy in neoplastic disease	0.145	0.855
M36.0 Dermato(poly)myositis in neoplastic disease	0.145	0.855
M54.8 Other dorsalgia	0.144	0.855
M54.0 Panniculitis affecting regions of neck and back	0.144	0.855
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.144	0.856
M25.89 Other specified joint disorders (Site unspecified)	0.144	0.856
M25.88 Other specified joint disorders (Other)	0.144	0.856
M25.83 Other specified joint disorders (Forearm)	0.144	0.856
M25.82 Other specified joint disorders (Upper arm)	0.144	0.856
M25.80 Other specified joint disorders (Multiple sites)	0.144	0.856
M21.29 Flexion deformity (Site unspecified)	0.143	0.856
M21.28 Flexion deformity (Other)	0.143	0.856
M21.25 Flexion deformity (Pelvic region and thigh)	0.143	0.856
M21.24 Flexion deformity (Hand)	0.143	0.856
M21.23 Flexion deformity (Forearm)	0.143	0.856
M21.22 Flexion deformity (Upper arm)	0.143	0.856
M21.21 Flexion deformity (Shoulder region)	0.143	0.856
M21.20 Flexion deformity (Multiple sites)	0.143	0.856
M25.87 Other specified joint disorders (Ankle and foot)	0.143	0.856
M50.1 Cervical disk disorder with radiculopathy	0.143	0.857
M54.9 Dorsalgia, unspecified	0.143	0.857
M20 Acquired deformities of fingers and toes	0.143	0.857
M15-M19 Arthrosis	0.143	0.857
M25.55 Pain in joint (Pelvic region and thigh)	0.142	0.858
M10 Gout	0.142	0.858
M89.94 Disorder of bone, unspecified (Hand)	0.142	0.858
M34.2 Systemic sclerosis induced by drugs and chemicals	0.141	0.858
M34.1 CR(E)ST syndrome	0.141	0.858
M34.0 Progressive systemic sclerosis	0.141	0.858
M54.5 Low back pain	0.141	0.859
M24.0 Loose body in joint	0.141	0.859
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.141	0.859
M21.68 Other acquired deformities of ankle and foot-Other	0.141	0.859
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.141	0.859
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.141	0.859
M21.64 Other acquired deformities of ankle and foot-Hand	0.141	0.859
M21.63 Other acquired deformities of ankle and foot-Forearm	0.141	0.859
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.141	0.859
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.141	0.859
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.141	0.859
M11 Other crystal arthropathies	0.140	0.860
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.139	0.861
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.139	0.861
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.139	0.861
M25.86 Other specified joint disorders (Lower leg)	0.139	0.861
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.139	0.861
M54.4 Lumbago with sciatica	0.139	0.861
M88 Paget's disease of bone [osteitis deformans]	0.138	0.861
M62.89 Other specified disorders of muscle (Site unspecified)	0.138	0.861
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.137	0.863
M93 Other osteochondropathies	0.137	0.863
M25.06 Haemarthrosis (Lower leg)	0.137	0.863
M62.9 Disorder of muscle, unspecified	0.137	0.863
M62.6 Muscle strain	0.137	0.863
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.137	0.863
M62.4 Contracture of muscle	0.137	0.863
M62.3 Immobility syndrome (paraplegic)	0.137	0.863
M62.2 Ischaemic infarction of muscle	0.137	0.863
M62.1 Other rupture of muscle (nontraumatic)	0.137	0.863
M62.0 Diastasis of muscle	0.137	0.863
M81.4 Drug-induced osteoporosis	0.137	0.863
M21.1 Varus deformity, not elsewhere classified	0.136	0.863
M91 Juvenile osteochondrosis of hip and pelvis	0.136	0.863
M23.4 Loose body in knee	0.136	0.864
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.135	0.864
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.135	0.864
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.135	0.865
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.135	0.865
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.135	0.865
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.135	0.865
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.135	0.865
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.135	0.865
M23.80 Other internal derangements of knee (Multiple sites)	0.135	0.865
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.135	0.865
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.135	0.865
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.135	0.865
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.135	0.865
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.135	0.865
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.135	0.865
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.135	0.865
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.135	0.865
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.135	0.865
M92 Other juvenile osteochondrosis	0.135	0.865
M84.3 Stress fracture, not elsewhere classified	0.135	0.865
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.134	0.865
M02 Reactive arthropathies	0.134	0.865
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.134	0.865
M62.86 Other specified disorders of muscle (Lower leg)	0.134	0.865
M90.7 Fracture of bone in neoplastic disease	0.134	0.865
M24.9 Joint derangement, unspecified	0.134	0.865
M24.7 Protrusio acetabuli	0.134	0.865
M24.6 Ankylosis of joint	0.134	0.865
M25.57 Pain in joint (Ankle and foot)	0.134	0.866
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.134	0.866
M89.6 Osteopathy after poliomyelitis	0.134	0.866
M89.5 Osteolysis	0.134	0.866
M89.4 Other hypertrophic osteo-arthropathy	0.134	0.866
M89.3 Hypertrophy of bone	0.134	0.866
M89.2 Other disorders of bone development and growth	0.134	0.866
M89.1 Epiphyseal arrest	0.134	0.866
M89.0 Algoneurodystrophy	0.134	0.866
M65.09 Abscess of tendon sheath (Site unspecified)	0.134	0.866
M65.08 Abscess of tendon sheath (Other)	0.134	0.866
M65.07 Abscess of tendon sheath (Ankle and foot)	0.134	0.866
M65.06 Abscess of tendon sheath (Lower leg)	0.134	0.866
M65.05 Abscess of tendon sheath (Pelvic region and thigh)	0.134	0.866
M65.04 Abscess of tendon sheath (Hand)	0.134	0.866
M65.03 Abscess of tendon sheath (Forearm)	0.134	0.866
M65.02 Abscess of tendon sheath (Upper arm)	0.134	0.866
M65.01 Abscess of tendon sheath (Shoulder region)	0.134	0.866
M65.00 Abscess of tendon sheath (Multiple sites)	0.134	0.866
M65.29 Calcific tendinitis (Site unspecified)	0.134	0.866
M65.28 Calcific tendinitis (Other)	0.134	0.866
M65.27 Calcific tendinitis (Ankle and foot)	0.134	0.866
M65.26 Calcific tendinitis (Lower leg)	0.134	0.866
M65.25 Calcific tendinitis (Pelvic region and thigh)	0.134	0.866
M65.24 Calcific tendinitis (Hand)	0.134	0.866
M65.23 Calcific tendinitis (Forearm)	0.134	0.866
M65.22 Calcific tendinitis (Upper arm)	0.134	0.866
M65.21 Calcific tendinitis (Shoulder region)	0.134	0.866
M65.20 Calcific tendinitis (Multiple sites)	0.134	0.866
M87 Osteonecrosis	0.133	0.866
M80.0 Postmenopausal osteoporosis with pathological fracture	0.133	0.867
M54.22 Cervicalgia (Cervical region)	0.133	0.867
M94 Other disorders of cartilage	0.133	0.867
M17 Gonarthrosis [arthrosis of knee]	0.132	0.868
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.132	0.868
M25.96 Joint disorder, unspecified (Lower leg)	0.132	0.868
M62.88 Other specified disorders of muscle (Other)	0.132	0.868
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.131	0.868
M65.88 Other synovitis and tenosynovitis (Other)	0.131	0.868
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.131	0.868
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.131	0.868
M65.84 Other synovitis and tenosynovitis (Hand)	0.131	0.868
M65.83 Other synovitis and tenosynovitis (Forearm)	0.131	0.868
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.131	0.868
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.131	0.868
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.131	0.868
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.131	0.868
M54.12 Radiculopathy (Cervical region)	0.131	0.869
M99 Biomechanical lesions, not elsewhere classified	0.131	0.869
M24.8 Other specific joint derangements, not elsewhere classified	0.131	0.869
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.131	0.869
M70-M79 Other soft tissue disorders	0.131	0.869
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.130	0.870
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.130	0.870
M66.28 Spontaneous rupture of extensor tendons-Other	0.130	0.870
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.130	0.870
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.130	0.870
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.130	0.870
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.130	0.870
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.130	0.870
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.130	0.870
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.130	0.870
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.130	0.870
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.130	0.870
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.130	0.870
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.130	0.870
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.130	0.870
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.130	0.870
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.130	0.870
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.130	0.870
M34.9 Systemic sclerosis, unspecified	0.130	0.870
M80.8 Other osteoporosis with pathological fracture	0.129	0.871
M80.5 Idiopathic osteoporosis with pathological fracture	0.129	0.871
M80.4 Drug-induced osteoporosis with pathological fracture	0.129	0.871
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.129	0.871
M80.2 Osteoporosis of disuse with pathological fracture	0.129	0.871
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.128	0.871
M89.8 Other specified disorders of bone	0.127	0.872
M84.1 Nonunion of fracture [pseudarthrosis]	0.127	0.873
M23.1 Discoid meniscus (congenital)	0.127	0.873
M23.0 Cystic meniscus	0.127	0.873
M00 Pyogenic arthritis	0.126	0.873
M10.9 Gout, unspecified	0.126	0.874
M23.9 Internal derangement of knee, unspecified	0.126	0.874
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.126	0.874
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.126	0.874
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.126	0.874
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.126	0.874
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.125	0.875
M35.0 Sicca syndrome [Sjogren]	0.125	0.875
M21.79 Unequal limb length (acquired) (Site unspecified)	0.124	0.876
M21.78 Unequal limb length (acquired)-Other	0.124	0.876
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.124	0.876
M21.76 Unequal limb length (acquired) (Lower leg)	0.124	0.876
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.124	0.876
M21.74 Unequal limb length (acquired) (Hand)	0.124	0.876
M21.73 Unequal limb length (acquired) (Forearm)	0.124	0.876
M21.72 Unequal limb length (acquired) (Upper arm)	0.124	0.876
M21.71 Unequal limb length (acquired)-Shldr region	0.124	0.876
M21.70 Unequal limb length (acquired) (Multiple sites)	0.124	0.876
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.124	0.876
M21.88 Other specified acquired deformities of limbs-Other	0.124	0.876
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.124	0.876
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.124	0.876
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.124	0.876
M21.84 Other specified acquired deformities of limbs (Hand)	0.124	0.876
M21.83 Other specified acquired deformities of limbs (Forearm)	0.124	0.876
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.124	0.876
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.124	0.876
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.124	0.876
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.124	0.876
M21.98 Acquired deformity of limb, unspecified-Other	0.124	0.876
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.124	0.876
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.124	0.876
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.124	0.876
M21.94 Acquired deformity of limb, unspecified (Hand)	0.124	0.876
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.124	0.876
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.124	0.876
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.124	0.876
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.124	0.876
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.124	0.876
M24.5 Contracture of joint	0.124	0.876
M42 Spinal osteochondrosis	0.124	0.876
M40 Kyphosis and lordosis	0.124	0.876
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.123	0.876
M21.39 Wrist or foot drop (acquired)-Site unspec	0.123	0.876
M21.38 Wrist or foot drop (acquired)-Other	0.123	0.876
M21.36 Wrist or foot drop (acquired)-Lower leg	0.123	0.876
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.123	0.876
M21.34 Wrist or foot drop (acquired) (Hand)	0.123	0.876
M21.33 Wrist or foot drop (acquired) (Forearm)	0.123	0.876
M21.32 Wrist or foot drop (acquired)-Upper arm	0.123	0.876
M21.31 Wrist or foot drop (acquired)-Shldr region	0.123	0.876
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.123	0.876
M11.2 Other chondrocalcinosis	0.124	0.876
M20.2 Hallux rigidus	0.124	0.876
M22.1 Recurrent subluxation of patella	0.123	0.877
M22.9 Disorder of patella, unspecified	0.123	0.877
M22.0 Recurrent dislocation of patella	0.123	0.877
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.123	0.877
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.123	0.877
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.122	0.877
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.122	0.877
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.122	0.878
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.122	0.878
M54.17 Radiculopathy (Lumbosacral region)	0.122	0.878
M54.15 Radiculopathy (Thoracolumbar region)	0.122	0.878
M54.14 Radiculopathy (Thoracic region)	0.122	0.878
M54.13 Radiculopathy (Cervicothoracic region)	0.122	0.878
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.122	0.878
M54.10 Radiculopathy (Multiple sites in spine)	0.122	0.878
M41 Scoliosis	0.122	0.878
M90.8 Osteopathy in other diseases classified elsewhere	0.121	0.879
M90.6 Osteitis deformans in neoplastic disease	0.121	0.879
M90.5 Osteonecrosis in other diseases classified elsewhere	0.121	0.879
M90.4 Osteonecrosis due to heamoglobinopathy	0.121	0.879
M90.3 Osteonecrosis in caisson disease	0.121	0.879
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.121	0.879
M90.1 Periostitis in other infectious diseases classified elsewhere	0.121	0.879
M90.0 Tuberculosis of bone	0.121	0.879
M22.2 Patellofemoral disorders	0.121	0.879
M89.99 Disorder of bone, unspecified (Site unspecified)	0.121	0.879
M89.98 Disorder of bone, unspecified (Other)	0.121	0.879
M89.96 Disorder of bone, unspecified (Lower leg)	0.121	0.879

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations