TreeWAS – Variant ID: rs5766691

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M47.96 Spondylosis, unspecified (Lumbar region)	0.942	0.058	0.000
M47.9 Spondylosis, unspecified	0.914	0.086	0.000
M47 Spondylosis	0.904	0.096	0.000
M47.2 Other spondylosis with radiculopathy	0.890	0.110	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.866	0.134	0.000
M45-M49 Spondylopathies	0.756	0.244	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.748	0.252	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.732	0.268	0.000
M48 Other spondylopathies	0.732	0.268	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.719	0.281	0.000
M48.0 Spinal stenosis	0.713	0.287	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.709	0.291	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.702	0.298	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.685	0.315	0.000
M47.8 Other spondylosis	0.675	0.325	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.656	0.344	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.651	0.349	0.000
M46 Other inflammatory spondylopathies	0.649	0.351	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.648	0.352	0.000
M47.1 Other spondylosis with myelopathy	0.646	0.354	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.638	0.362	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.638	0.362	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.638	0.362	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.638	0.362	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.638	0.362	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.638	0.362	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.610	0.390	0.000
M48.8 Other specified spondylopathies	0.605	0.395	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.603	0.397	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.595	0.405	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.589	0.410	0.000
M47.89 Other spondylosis (Site unspecified)	0.584	0.416	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.570	0.430	0.000
M48.06 Spinal stenosis (Lumbar region)	0.554	0.446	0.000
M47.84 Other spondylosis (Thoracic region)	0.551	0.449	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.546	0.454	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.544	0.455	0.000
M48.04 Spinal stenosis (Thoracic region)	0.534	0.466	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.531	0.469	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.531	0.469	0.000
M46.4 Discitis, unspecified	0.528	0.471	0.000
M49 Spondylopathies in diseases classified elsewhere	0.528	0.472	0.000
M48.4 Fatigue fracture of vertebra	0.525	0.475	0.000
M48.3 Traumatic spondylopathy	0.525	0.475	0.000
M48.2 Kissing spine	0.525	0.475	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.525	0.475	0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.521	0.479	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.511	0.488	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.511	0.488	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.506	0.494	0.000
M48.9 Spondylopathy, unspecified	0.499	0.501	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.494	0.506	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.494	0.506	0.000
M46.2 Osteomyelitis of vertebra	0.491	0.509	0.000
M46.0 Spinal enthesopathy	0.489	0.511	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.484	0.516	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.483	0.517	0.000
M48.09 Spinal stenosis (Site unspecified)	0.480	0.520	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.477	0.522	0.000
M46.8 Other specified inflammatory spondylopathies	0.465	0.535	0.000
M46.5 Other infective spondylopathies	0.465	0.535	0.000
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)	0.465	0.535	0.000
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)	0.465	0.535	0.000
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)	0.465	0.535	0.000
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)	0.465	0.535	0.000
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)	0.465	0.535	0.000
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)	0.465	0.535	0.000
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)	0.465	0.535	0.000
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)	0.465	0.535	0.000
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)	0.465	0.535	0.000
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)	0.465	0.535	0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.463	0.537	0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.463	0.537	0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.463	0.537	0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.463	0.537	0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.463	0.537	0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.463	0.537	0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.463	0.537	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.463	0.537	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.462	0.538	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.459	0.541	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.446	0.554	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.437	0.562	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.434	0.566	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.434	0.566	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.434	0.566	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.434	0.566	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.434	0.566	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.427	0.573	0.000
M46.49 Discitis, unspecified (Site unspecified)	0.426	0.574	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.426	0.574	0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.425	0.575	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.424	0.575	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.422	0.578	0.000
M46.40 Discitis, unspecified (Multiple sites in spine)	0.397	0.603	0.000
M46.42 Discitis, unspecified (Cervical region)	0.392	0.608	0.000
M46.47 Discitis, unspecified (Lumbosacral region)	0.390	0.610	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.390	0.610	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.387	0.613	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.381	0.619	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.381	0.619	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.381	0.619	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.381	0.619	0.000
M46.44 Discitis, unspecified (Thoracic region)	0.380	0.620	0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)	0.379	0.621	0.000
M46.45 Discitis, unspecified (Thoracolumbar region)	0.379	0.621	0.000
M46.43 Discitis, unspecified (Cervicothoracic region)	0.379	0.621	0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)	0.379	0.621	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.378	0.621	0.000
M49.4 Neuropathic spondylopathy	0.378	0.621	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.378	0.621	0.000
M49.2 Enterobacterial spondylitis	0.378	0.621	0.000
M49.1 Brucella spondylitis	0.378	0.621	0.000
M49.0 Tuberculosis of spine	0.378	0.621	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.378	0.622	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.376	0.623	0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.376	0.623	0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.376	0.623	0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.376	0.623	0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.376	0.623	0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.376	0.623	0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.376	0.623	0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.376	0.623	0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.376	0.623	0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.376	0.623	0.000
M48.29 Kissing spine (Site unspecified)	0.376	0.623	0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.376	0.623	0.000
M48.27 Kissing spine (Lumbosacral region)	0.376	0.623	0.000
M48.26 Kissing spine (Lumbar region)	0.376	0.623	0.000
M48.25 Kissing spine (Thoracolumbar region)	0.376	0.623	0.000
M48.24 Kissing spine (Thoracic region)	0.376	0.623	0.000
M48.23 Kissing spine (Cervicothoracic region)	0.376	0.623	0.000
M48.22 Kissing spine (Cervical region)	0.376	0.623	0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.376	0.623	0.000
M48.20 Kissing spine (Multiple sites in spine)	0.376	0.623	0.000
M48.39 Traumatic spondylopathy (Site unspecified)	0.376	0.623	0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.376	0.623	0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.376	0.623	0.000
M48.36 Traumatic spondylopathy (Lumbar region)	0.376	0.623	0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.376	0.623	0.000
M48.34 Traumatic spondylopathy (Thoracic region)	0.376	0.623	0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.376	0.623	0.000
M48.32 Traumatic spondylopathy (Cervical region)	0.376	0.623	0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.376	0.623	0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.376	0.623	0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.376	0.623	0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.376	0.623	0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.376	0.623	0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.376	0.623	0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.376	0.623	0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.376	0.623	0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.376	0.623	0.000
M48.42 Fatigue fracture of vertebra (Cervical region)	0.376	0.623	0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.376	0.623	0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.376	0.623	0.000
M46.06 Spinal enthesopathy (Lumbar region)	0.375	0.625	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.375	0.625	0.000
M46.24 Osteomyelitis of vertebra (Thoracic region)	0.370	0.629	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.369	0.630	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.364	0.636	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.362	0.638	0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)	0.361	0.639	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.358	0.642	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.358	0.642	0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.358	0.642	0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.358	0.642	0.000
M48.94 Spondylopathy, unspecified (Thoracic region)	0.358	0.642	0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.358	0.642	0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.358	0.642	0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.358	0.642	0.000
M46.29 Osteomyelitis of vertebra (Site unspecified)	0.352	0.648	0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)	0.352	0.648	0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)	0.352	0.648	0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)	0.352	0.648	0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)	0.352	0.648	0.000
M46.22 Osteomyelitis of vertebra (Cervical region)	0.352	0.648	0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)	0.352	0.648	0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)	0.352	0.648	0.000
M46.09 Spinal enthesopathy (Site unspecified)	0.351	0.649	0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)	0.351	0.649	0.000
M46.07 Spinal enthesopathy (Lumbosacral region)	0.351	0.649	0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)	0.351	0.649	0.000
M46.04 Spinal enthesopathy (Thoracic region)	0.351	0.649	0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)	0.351	0.649	0.000
M46.02 Spinal enthesopathy (Cervical region)	0.351	0.649	0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)	0.351	0.649	0.000
M46.00 Spinal enthesopathy (Multiple sites in spine)	0.351	0.649	0.000
M48.92 Spondylopathy, unspecified (Cervical region)	0.339	0.661	0.000
M46.59 Other infective spondylopathies (Site unspecified)	0.333	0.666	0.000
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)	0.333	0.666	0.000
M46.57 Other infective spondylopathies (Lumbosacral region)	0.333	0.666	0.000
M46.56 Other infective spondylopathies (Lumbar region)	0.333	0.666	0.000
M46.55 Other infective spondylopathies (Thoracolumbar region)	0.333	0.666	0.000
M46.54 Other infective spondylopathies (Thoracic region)	0.333	0.666	0.000
M46.53 Other infective spondylopathies (Cervicothoracic region)	0.333	0.666	0.000
M46.52 Other infective spondylopathies (Cervical region)	0.333	0.666	0.000
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)	0.333	0.666	0.000
M46.50 Other infective spondylopathies (Multiple sites in spine)	0.333	0.666	0.000
M46.89 Other specified inflammatory spondylopathies (Site unspecified)	0.333	0.666	0.000
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)	0.333	0.666	0.000
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)	0.333	0.666	0.000
M46.86 Other specified inflammatory spondylopathies (Lumbar region)	0.333	0.666	0.000
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)	0.333	0.666	0.000
M46.84 Other specified inflammatory spondylopathies (Thoracic region)	0.333	0.666	0.000
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)	0.333	0.666	0.000
M46.82 Other specified inflammatory spondylopathies (Cervical region)	0.333	0.666	0.000
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)	0.333	0.666	0.000
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)	0.333	0.666	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.332	0.668	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.332	0.668	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.332	0.668	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.332	0.668	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.332	0.668	0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.329	0.671	0.000
M48.99 Spondylopathy, unspecified (Site unspecified)	0.326	0.673	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.325	0.675	0.001
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.322	0.678	0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar	0.320	0.680	0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar	0.320	0.680	0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic	0.320	0.680	0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic	0.320	0.680	0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical	0.320	0.680	0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl	0.320	0.680	0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site	0.320	0.680	0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)	0.314	0.686	0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral	0.312	0.687	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.304	0.695	0.000
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)	0.304	0.695	0.000
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)	0.304	0.695	0.000
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)	0.304	0.695	0.000
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)	0.304	0.695	0.000
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)	0.304	0.695	0.000
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)	0.304	0.695	0.000
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)	0.304	0.695	0.000
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)	0.304	0.695	0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.298	0.702	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.292	0.707	0.000
M48.02 Spinal stenosis (Cervical region)	0.276	0.724	0.000
M49.09 Tuberculosis of spine (Site unspecified)	0.271	0.728	0.000
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)	0.271	0.728	0.000
M49.07 Tuberculosis of spine (Lumbosacral region)	0.271	0.728	0.000
M49.06 Tuberculosis of spine (Lumbar region)	0.271	0.728	0.000
M49.05 Tuberculosis of spine (Thoracolumbar region)	0.271	0.728	0.000
M49.04 Tuberculosis of spine (Thoracic region)	0.271	0.728	0.000
M49.03 Tuberculosis of spine (Cervicothoracic region)	0.271	0.728	0.000
M49.02 Tuberculosis of spine (Cervical region)	0.271	0.728	0.000
M49.01 Tuberculosis of spine (Occipito-atlanto-axial region)	0.271	0.728	0.000
M49.00 Tuberculosis of spine (Multiple sites in spine)	0.271	0.728	0.000
M49.19 Brucella spondylitis (Site unspecified)	0.271	0.728	0.000
M49.18 Brucella spondylitis (Sacral and sacrococcygeal region)	0.271	0.728	0.000
M49.17 Brucella spondylitis (Lumbosacral region)	0.271	0.728	0.000
M49.16 Brucella spondylitis (Lumbar region)	0.271	0.728	0.000
M49.15 Brucella spondylitis (Thoracolumbar region)	0.271	0.728	0.000
M49.14 Brucella spondylitis (Thoracic region)	0.271	0.728	0.000
M49.13 Brucella spondylitis (Cervicothoracic region)	0.271	0.728	0.000
M49.12 Brucella spondylitis (Cervical region)	0.271	0.728	0.000
M49.11 Brucella spondylitis (Occipito-atlanto-axial region)	0.271	0.728	0.000
M49.10 Brucella spondylitis (Multiple sites in spine)	0.271	0.728	0.000
M49.29 Enterobacterial spondylitis (Site unspecified)	0.271	0.728	0.000
M49.28 Enterobacterial spondylitis (Sacral and sacrococcygeal region)	0.271	0.728	0.000
M49.27 Enterobacterial spondylitis (Lumbosacral region)	0.271	0.728	0.000
M49.26 Enterobacterial spondylitis (Lumbar region)	0.271	0.728	0.000
M49.25 Enterobacterial spondylitis (Thoracolumbar region)	0.271	0.728	0.000
M49.24 Enterobacterial spondylitis (Thoracic region)	0.271	0.728	0.000
M49.23 Enterobacterial spondylitis (Cervicothoracic region)	0.271	0.728	0.000
M49.22 Enterobacterial spondylitis (Cervical region)	0.271	0.728	0.000
M49.21 Enterobacterial spondylitis (Occipito-atlanto-axial region)	0.271	0.728	0.000
M49.20 Enterobacterial spondylitis (Multiple sites in spine)	0.271	0.728	0.000
M49.39 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Site unspecified)	0.271	0.728	0.000
M49.38 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Sacral and sacrococcygeal region)	0.271	0.728	0.000
M49.37 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbosacral region)	0.271	0.728	0.000
M49.36 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbar region)	0.271	0.728	0.000
M49.35 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracolumbar region)	0.271	0.728	0.000
M49.34 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracic region)	0.271	0.728	0.000
M49.33 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervicothoracic region)	0.271	0.728	0.000
M49.32 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervical region)	0.271	0.728	0.000
M49.31 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Occipito-atlanto-axial region)	0.271	0.728	0.000
M49.30 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Multiple sites in spine)	0.271	0.728	0.000
M49.49 Neuropathic spondylopathy (Site unspecified)	0.271	0.728	0.000
M49.48 Neuropathic spondylopathy (Sacral and sacrococcygeal region)	0.271	0.728	0.000
M49.47 Neuropathic spondylopathy (Lumbosacral region)	0.271	0.728	0.000
M49.46 Neuropathic spondylopathy (Lumbar region)	0.271	0.728	0.000
M49.45 Neuropathic spondylopathy (Thoracolumbar region)	0.271	0.728	0.000
M49.44 Neuropathic spondylopathy (Thoracic region)	0.271	0.728	0.000
M49.43 Neuropathic spondylopathy (Cervicothoracic region)	0.271	0.728	0.000
M49.42 Neuropathic spondylopathy (Cervical region)	0.271	0.728	0.000
M49.41 Neuropathic spondylopathy (Occipito-atlanto-axial region)	0.271	0.728	0.000
M49.40 Neuropathic spondylopathy (Multiple sites in spine)	0.271	0.728	0.000
M49.89 Spondylopathy in other diseases classified elsewhere (Site unspecified)	0.271	0.728	0.000
M49.88 Spondylopathy in other diseases classified elsewhere (Sacral and sacrococcygeal region)	0.271	0.728	0.000
M49.87 Spondylopathy in other diseases classified elsewhere (Lumbosacral region)	0.271	0.728	0.000
M49.86 Spondylopathy in other diseases classified elsewhere (Lumbar region)	0.271	0.728	0.000
M49.85 Spondylopathy in other diseases classified elsewhere (Thoracolumbar region)	0.271	0.728	0.000
M49.84 Spondylopathy in other diseases classified elsewhere (Thoracic region)	0.271	0.728	0.000
M49.83 Spondylopathy in other diseases classified elsewhere (Cervicothoracic region)	0.271	0.728	0.000
M49.82 Spondylopathy in other diseases classified elsewhere (Cervical region)	0.271	0.728	0.000
M49.81 Spondylopathy in other diseases classified elsewhere (Occipito-atlanto-axial region)	0.271	0.728	0.000
M49.80 Spondylopathy in other diseases classified elsewhere (Multiple sites in spine)	0.271	0.728	0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.268	0.732	0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.268	0.732	0.000
M45 Ankylosing spondylitis	0.263	0.736	0.000
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)	0.261	0.739	0.000
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)	0.261	0.739	0.000
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)	0.261	0.739	0.000
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)	0.261	0.739	0.000
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)	0.261	0.739	0.000
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)	0.261	0.739	0.000
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)	0.261	0.739	0.000
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)	0.250	0.749	0.000
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)	0.231	0.769	0.000
M47.82 Other spondylosis (Cervical region)	0.206	0.794	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.197	0.802	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.192	0.807	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.192	0.808	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.189	0.811	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.189	0.811	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.189	0.811	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.189	0.811	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.189	0.811	0.000
Z60.2 Living alone	0.000	0.815	0.185
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.178	0.822	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.174	0.826	0.000
Z60 Problems related to social environment	0.000	0.849	0.151
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.000	0.865	0.135
Z58 Problems related to physical environment	0.000	0.870	0.130
Z58.1 Exposure to air pollution	0.000	0.875	0.125
Z63 Other problems related to primary support group, including family circumstances	0.000	0.878	0.122
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.117	0.882	0.001
Z60.9 Problem related to social environment, unspecified	0.000	0.887	0.113
Z61 Problems related to negative life events in childhood	0.000	0.887	0.113
Z60.5 Target of perceived adverse discrimination and persecution	0.000	0.891	0.109
Z60.4 Social exclusion and rejection	0.000	0.891	0.109
Z60.3 Acculturation difficulty	0.000	0.891	0.109
Z60.1 Atypical parenting situation	0.000	0.891	0.109
Z60.0 Problems of adjustment to life-cycle transitions	0.000	0.891	0.109
Z63.4 Disappearance and death of family member	0.000	0.892	0.108
Z56 Problems related to employment and unemployment	0.000	0.896	0.104
Z63.8 Other specified problems related to primary support group	0.000	0.897	0.103
Z63.7 Other stressful life events affecting family and household	0.000	0.897	0.103
Z58.8 Other problems related to physical environment	0.000	0.899	0.101
M45.X9 Ankylosing spondylitis (Site unspecified)	0.100	0.900	0.000
Z64 Problems related to certain psychosocial circumstances	0.000	0.900	0.099
Z62 Other problems related to upbringing	0.000	0.903	0.097
Z55 Problems related to education and literacy	0.000	0.903	0.097
Z58.5 Exposure to other pollution	0.000	0.903	0.097
Z58.9 Problem related to physical environment, unspecified	0.000	0.907	0.093
Z58.6 Inadequate drinking-water supply	0.000	0.907	0.093
Z58.4 Exposure to radiation	0.000	0.907	0.093
Z58.3 Exposure to soil pollution	0.000	0.907	0.093
Z58.2 Exposure to water pollution	0.000	0.907	0.093
Z58.0 Exposure to noise	0.000	0.907	0.093
Z63.5 Disruption of family by separation and divorce	0.000	0.909	0.091
Z59 Problems related to housing and economic circumstances	0.000	0.909	0.091
Z65 Problems related to other psychosocial circumstances	0.000	0.909	0.091
Z61.6 Problems related to alleged physical abuse of child	0.000	0.910	0.090
Z56.0 Unemployment, unspecified	0.000	0.912	0.088
Z58.7 Exposure to tobacco smoke	0.000	0.912	0.088
Z63.9 Problem related to primary support group, unspecified	0.000	0.912	0.088
Z63.3 Absence of family member	0.000	0.912	0.088
Z63.2 Inadequate family support	0.000	0.912	0.088
Z63.1 Problems in relationship with parents and in-laws	0.000	0.912	0.088
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.000	0.912	0.088
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.000	0.914	0.086
Z60.8 Other problems related to social environment	0.000	0.917	0.083
Z61.9 Negative life events in childhood, unspecified	0.000	0.919	0.081
Z61.8 Other negative life events in childhood	0.000	0.919	0.081
Z61.7 Personal frightening experience in childhood	0.000	0.919	0.081
Z61.3 Events resulting in loss of self-esteem in childhood	0.000	0.919	0.081
Z61.2 Altered pattern of family relationships in childhood	0.000	0.919	0.081
Z61.1 Removal from home in childhood	0.000	0.919	0.081
Z61.0 Loss of love relationship in childhood	0.000	0.919	0.081
Z59.8 Other problems relating to housing and economic circumstances	0.000	0.920	0.080
Z56.3 Stressful work schedule	0.000	0.921	0.079
Z56.7 Other and unspecified problems related to employment	0.000	0.922	0.078
Z56.5 Uncongenial work	0.000	0.925	0.074
Z56.4 Discord with boss and workmates	0.000	0.925	0.074
Z56.2 Threat of job loss	0.000	0.925	0.074
Z56.1 Change of job	0.000	0.925	0.074
Z64.0 Problems related to unwanted pregnancy	0.000	0.926	0.074
Z64.4 Discord with counsellors	0.000	0.928	0.071
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.000	0.928	0.071
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.000	0.928	0.071
Z64.1 Problems related to multiparity	0.000	0.928	0.071
Z59.1 Inadequate housing	0.000	0.928	0.071
Z63.6 Dependent relative needing care at home	0.000	0.929	0.071
Z63.0 Problems in relationship with spouse or partner	0.000	0.929	0.071
Z65.3 Problems related to other legal circumstances	0.000	0.930	0.070
Z55.9 Problems relating to education and literacy, unspecified	0.000	0.930	0.070
Z55.8 Other problems relating to education and literacy	0.000	0.930	0.070
Z55.4 Educational maladjustment and discord with teachers and classmates	0.000	0.930	0.070
Z55.3 Underachievement in school	0.000	0.930	0.070
Z55.2 Failed examinations	0.000	0.930	0.070
Z55.1 Schooling unavailable and unattainable	0.000	0.930	0.070
Z55.0 Illiteracy and low-level literacy	0.000	0.930	0.070
Z62.9 Problem related to upbringing, unspecified	0.000	0.930	0.070
Z62.8 Other specified problems related to upbringing	0.000	0.930	0.070
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.000	0.930	0.070
Z62.5 Other problems related to neglect in upbringing	0.000	0.930	0.070
Z62.4 Emotional neglect of child	0.000	0.930	0.070
Z62.3 Hostility towards and scapegoating of child	0.000	0.930	0.070
Z62.2 Institutional upbringing	0.000	0.930	0.070
Z62.1 Parental overprotection	0.000	0.930	0.070
Z62.0 Inadequate parental supervision and control	0.000	0.930	0.070
M47.86 Other spondylosis (Lumbar region)	0.069	0.930	0.000
Z59.7 Insufficient social insurance and welfare support	0.000	0.934	0.065
Z59.6 Low income	0.000	0.934	0.065
Z59.5 Extreme poverty	0.000	0.934	0.065
Z59.3 Problems related to living in residential institution	0.000	0.934	0.065
Z65.5 Exposure to disaster, war and other hostilities	0.000	0.934	0.065
Z65.4 Victim of crime and terrorism	0.000	0.934	0.065
Z65.2 Problems related to release from prison	0.000	0.934	0.065
Z65.1 Imprisonment and other incarceration	0.000	0.934	0.065
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.000	0.934	0.065
Z59.2 Discord with neighbours, lodgers and landlord	0.000	0.936	0.063
Z65.8 Other specified problems related to psychosocial circumstances	0.000	0.939	0.061
Z59.4 Lack of adequate food	0.000	0.941	0.059
Z65.9 Problem related to unspecified psychosocial circumstances	0.000	0.941	0.058
Z59.0 Homelessness	0.000	0.949	0.050
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.000	0.950	0.050
Z56.6 Other physical and mental strain related to work	0.000	0.953	0.046
Z57 Occupational exposure to risk-factors	0.000	0.968	0.032
Z57.9 Occupational exposure to unspecified risk-factor	0.000	0.977	0.023
Z57.7 Occupational exposure to vibration	0.000	0.977	0.023
Z57.6 Occupational exposure to extreme temperature	0.000	0.977	0.023
Z57.4 Occupational exposure to toxic agents in agriculture	0.000	0.977	0.023
Z57.1 Occupational exposure to radiation	0.000	0.977	0.023
Z57.0 Occupational exposure to noise	0.000	0.977	0.023
R25.2 Cramp and spasm	0.023	0.977	0.000
Z57.8 Occupational exposure to other risk-factors	0.000	0.980	0.020
Z57.3 Occupational exposure to other air contaminants	0.000	0.981	0.019
R25 Abnormal involuntary movements	0.018	0.982	0.000
R25.3 Fasciculation	0.017	0.983	0.000
M31.6 Other giant cell arteritis	0.000	0.983	0.017
R25.8 Other and unspecified abnormal involuntary movements	0.016	0.984	0.000
Z57.2 Occupational exposure to dust	0.000	0.984	0.016
M31.3 Wegener's granulomatosis	0.000	0.986	0.014
M31 Other necrotising vasculopathies	0.000	0.987	0.013
R25.0 Abnormal head movements	0.013	0.987	0.000
K82.4 Cholesterolosis of gallbladder	0.013	0.987	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.988	0.012
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.989	0.011
M31.1 Thrombotic microangiopathy	0.000	0.990	0.010
M31.7 Microscopic polyangiitis	0.000	0.990	0.010
M31.8 Other specified necrotising vasculopathies	0.000	0.990	0.010
M31.2 Lethal midline granuloma	0.000	0.990	0.010
C83.3 Large cell (diffuse)	0.010	0.990	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.991	0.009
K85.9 Acute pancreatitis, unspecified	0.008	0.992	0.000
Z49.1 Extracorporeal dialysis	0.007	0.992	0.000
M31.0 Hypersensitivity angiitis	0.000	0.993	0.007
R25.1 Tremor, unspecified	0.007	0.993	0.000
G57.6 Lesion of plantar nerve	0.007	0.993	0.000
M31.9 Necrotising vasculopathy, unspecified	0.000	0.993	0.007
G57.8 Other mononeuropathies of lower limb	0.007	0.993	0.000
L65.9 Nonscarring hair loss, unspecified	0.000	0.994	0.006
I12.0 Hypertensive renal disease with renal failure	0.006	0.994	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.006	0.994	0.000
G43.9 Migraine, unspecified	0.006	0.994	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.994	0.006
G57 Mononeuropathies of lower limb	0.006	0.994	0.000
K57.2 Diverticular disease of large intestine with perforation and abscess	0.000	0.995	0.005
S32.50 Fracture of pubis (closed)	0.005	0.995	0.000
R06.8 Other and unspecified abnormalities of breathing	0.005	0.995	0.000
Z94.8 Other transplanted organ and tissue status	0.005	0.995	0.000
G57.3 Lesion of lateral popliteal nerve	0.005	0.995	0.000
N13.3 Other and unspecified hydronephrosis	0.000	0.995	0.005
D68.2 Hereditary deficiency of other clotting factors	0.000	0.995	0.005
O16 Unspecified maternal hypertension	0.000	0.996	0.004
G57.4 Lesion of medial popliteal nerve	0.004	0.996	0.000
G57.2 Lesion of femoral nerve	0.004	0.996	0.000
N13 Obstructive and reflux uropathy	0.000	0.996	0.004
D68 Other coagulation defects	0.000	0.996	0.004
H16.0 Corneal ulcer	0.000	0.996	0.004
D68.8 Other specified coagulation defects	0.000	0.996	0.004
D68.6 Other Thrombophilia	0.000	0.996	0.004
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.996	0.004
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.996	0.004
S92.10 Fracture of talus (closed)	0.000	0.996	0.004
S92 Fracture of foot, except ankle	0.000	0.996	0.004
G57.5 Tarsal tunnel syndrome	0.004	0.996	0.000
S32.5 Fracture of pubis	0.004	0.996	0.000
N13.6 Pyonephrosis	0.000	0.996	0.004
G57.9 Mononeuropathy of lower limb, unspecified	0.004	0.996	0.000
S92.50 Fracture of other toe (closed)	0.000	0.996	0.004
S92.5 Fracture of other toe	0.000	0.996	0.004
S92.1 Fracture of talus	0.000	0.996	0.004
D68.9 Coagulation defect, unspecified	0.000	0.996	0.004
H53.0 Amblyopia ex anopsia	0.004	0.996	0.000
L65 Other nonscarring hair loss	0.000	0.996	0.004
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.996	0.004
G57.0 Lesion of sciatic nerve	0.003	0.996	0.000
M89.9 Disorder of bone, unspecified	0.000	0.996	0.004
S92.2 Fracture of other tarsal bone(s)	0.000	0.996	0.004
S92.7 Multiple fractures of foot	0.000	0.996	0.003
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.996	0.004
Z49 Care involving dialysis	0.004	0.996	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.996	0.003
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.997	0.003
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.997	0.003
D68.1 Hereditary factor XI deficiency	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations