TreeWAS – Variant ID: rs584480

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E29.1 Testicular hypofunction	0.116	0.884	0.000
E29 Testicular dysfunction	0.064	0.936	0.000
I24.8 Other forms of acute ischaemic heart disease	0.000	0.941	0.059
E29.9 Testicular dysfunction, unspecified	0.049	0.951	0.000
E29.8 Other testicular dysfunction	0.046	0.954	0.000
E29.0 Testicular hyperfunction	0.046	0.954	0.000
O80.9 Single spontaneous delivery, unspecified	0.000	0.959	0.041
O80 Single spontaneous delivery	0.000	0.960	0.040
O80.0 Spontaneous vertex delivery	0.000	0.960	0.040
O80.8 Other single spontaneous delivery	0.000	0.964	0.036
O80.1 Spontaneous breech delivery	0.000	0.971	0.029
O80-O84 Delivery	0.000	0.977	0.023
E24 Cushing's syndrome	0.022	0.978	0.000
E20-E35 Disorders of other endocrine glands	0.021	0.979	0.000
C71.9 Brain, unspecified	0.021	0.979	0.000
E24.9 Cushing's syndrome, unspecified	0.020	0.980	0.000
O81 Single delivery by forceps and vacuum extractor	0.000	0.981	0.019
E24.0 Pituitary-dependent Cushing's disease	0.018	0.981	0.000
E27 Other disorders of adrenal gland	0.018	0.982	0.000
E24.2 Drug-induced Cushing's syndrome	0.018	0.982	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.018	0.982	0.000
E24.8 Other Cushing's syndrome	0.018	0.982	0.000
O82 Single delivery by Caesarean section	0.000	0.982	0.018
O84 Multiple delivery	0.000	0.983	0.017
O83 Other assisted single delivery	0.000	0.983	0.017
O81.3 Other and unspecified forceps delivery	0.000	0.984	0.016
O81.0 Low forceps delivery	0.000	0.984	0.016
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.016	0.984	0.000
E24.3 Ectopic ACTH syndrome	0.016	0.984	0.000
E24.1 Nelson's syndrome	0.016	0.984	0.000
E27.9 Disorder of adrenal gland, unspecified	0.016	0.984	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.015	0.984	0.000
E32 Diseases of thymus	0.015	0.984	0.000
E30 Disorders of puberty, not elsewhere classified	0.015	0.984	0.000
O82.0 Delivery by elective Caesarean section	0.000	0.985	0.015
E26 Hyperaldosteronism	0.015	0.985	0.000
E25 Adrenogenital disorders	0.015	0.985	0.000
E31 Polyglandular dysfunction	0.015	0.985	0.000
E23 Hypofunction and other disorders of pituitary gland	0.015	0.985	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.000	0.986	0.014
O81.2 Mid-cavity forceps with rotation	0.000	0.986	0.014
O81.1 Mid-cavity forceps delivery	0.000	0.986	0.014
E27.8 Other specified disorders of adrenal gland	0.014	0.986	0.000
E20 Hypoparathyroidism	0.013	0.986	0.000
E27.5 Adrenomedullary hyperfunction	0.013	0.987	0.000
E27.0 Other adrenocortical overactivity	0.013	0.987	0.000
O82.8 Other single delivery by Caesarean section	0.000	0.987	0.013
O82.2 Delivery by Caesarean hysterectomy	0.000	0.987	0.013
O82.1 Delivery by emergency Caesarean section	0.000	0.987	0.013
C71.2 Temporal lobe	0.013	0.987	0.000
C71 Malignant neoplasm of brain	0.013	0.987	0.000
O83.9 Assisted single delivery, unspecified	0.000	0.988	0.012
O83.8 Other specified assisted single delivery	0.000	0.988	0.012
O83.4 Destructive operation for delivery	0.000	0.988	0.012
O83.3 Delivery of viable foetus in abdominal pregnancy	0.000	0.988	0.012
O83.2 Other manipulation-assisted delivery	0.000	0.988	0.012
O83.1 Other assisted breech delivery	0.000	0.988	0.012
O83.0 Breech extraction	0.000	0.988	0.012
O84.9 Multiple delivery, unspecified	0.000	0.988	0.012
O84.8 Other multiple delivery	0.000	0.988	0.012
O84.2 Multiple delivery, all by Caesarean section	0.000	0.988	0.012
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.000	0.988	0.012
O84.0 Multiple delivery, all spontaneous	0.000	0.988	0.012
E23.0 Hypopituitarism	0.012	0.988	0.000
E26.9 Hyperaldosteronism, unspecified	0.012	0.988	0.000
E30.9 Disorder of puberty, unspecified	0.011	0.989	0.000
E30.8 Other disorders of puberty	0.011	0.989	0.000
E30.1 Precocious puberty	0.011	0.989	0.000
E30.0 Delayed puberty	0.011	0.989	0.000
E32.9 Disease of thymus, unspecified	0.011	0.989	0.000
E32.8 Other diseases of thymus	0.011	0.989	0.000
E32.1 Abscess of thymus	0.011	0.989	0.000
E32.0 Persistent hyperplasia of thymus	0.011	0.989	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.011	0.989	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.011	0.989	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.011	0.989	0.000
E25.9 Adrenogenital disorder, unspecified	0.011	0.989	0.000
E25.8 Other adrenogenital disorders	0.011	0.989	0.000
E26.8 Other hyperaldosteronism	0.011	0.989	0.000
E26.1 Secondary hyperaldosteronism	0.011	0.989	0.000
E22 Hyperfunction of pituitary gland	0.011	0.989	0.000
O82.9 Delivery by Caesarean section, unspecified	0.000	0.989	0.011
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.011	0.989	0.000
E27.2 Addisonian crisis	0.011	0.989	0.000
E31.9 Polyglandular dysfunction, unspecified	0.011	0.989	0.000
E31.8 Other polyglandular dysfunction	0.011	0.989	0.000
E31.1 Polyglandular hyperfunction	0.011	0.989	0.000
E34 Other endocrine disorders	0.011	0.989	0.000
E23.6 Other disorders of pituitary gland	0.011	0.989	0.000
E28 Ovarian dysfunction	0.011	0.989	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.011	0.989	0.000
E23.1 Drug-induced hypopituitarism	0.011	0.989	0.000
S82.00 Fracture of patella (closed)	0.011	0.989	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.010	0.989	0.000
E26.0 Primary hyperaldosteronism	0.010	0.989	0.000
E31.0 Autoimmune polyglandular failure	0.010	0.990	0.000
O81.4 Vacuum extractor delivery	0.000	0.990	0.010
C71.3 Parietal lobe	0.010	0.990	0.000
C71.7 Brain stem	0.010	0.990	0.000
E23.7 Disorder of pituitary gland, unspecified	0.010	0.990	0.000
C71.5 Cerebral ventricle	0.010	0.990	0.000
E20.8 Other hypoparathyroidism	0.010	0.990	0.000
E20.1 Pseudohypoparathyroidism	0.010	0.990	0.000
E20.0 Idiopathic hypoparathyroidism	0.010	0.990	0.000
C71.6 Cerebellum	0.009	0.990	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.009	0.991	0.000
E34.8 Other specified endocrine disorders	0.009	0.991	0.000
C71.4 Occipital lobe	0.009	0.991	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.008	0.991	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.009	0.991	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.008	0.992	0.000
E22.8 Other hyperfunction of pituitary gland	0.008	0.992	0.000
E34.5 Androgen resistance syndrome	0.008	0.992	0.000
E34.4 Constitutional tall stature	0.008	0.992	0.000
E34.3 Short stature, not elsewhere classified	0.008	0.992	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.008	0.992	0.000
E34.1 Other hypersecretion of intestinal hormones	0.008	0.992	0.000
E28.9 Ovarian dysfunction, unspecified	0.008	0.992	0.000
E28.8 Other ovarian dysfunction	0.008	0.992	0.000
E28.1 Androgen excess	0.008	0.992	0.000
E28.0 Oestrogen excess	0.008	0.992	0.000
E22.1 Hyperprolactinaemia	0.008	0.992	0.000
E23.2 Diabetes insipidus	0.008	0.992	0.000
E20.9 Hypoparathyroidism, unspecified	0.008	0.992	0.000
C71.8 Overlapping lesion of brain	0.007	0.992	0.000
E27.1 Primary adrenocortical insufficiency	0.007	0.992	0.000
I24 Other acute ischaemic heart diseases	0.003	0.993	0.004
E21.5 Disorder of parathyroid gland, unspecified	0.007	0.993	0.000
C71.1 Frontal lobe	0.007	0.993	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.007	0.993	0.000
E21.2 Other hyperparathyroidism	0.007	0.993	0.000
C71.0 Cerebrum, except lobes and ventricles	0.006	0.993	0.000
E21.4 Other specified disorders of parathyroid gland	0.006	0.994	0.000
E28.3 Primary ovarian failure	0.006	0.994	0.000
E22.0 Acromegaly and pituitary gigantism	0.006	0.994	0.000
E28.2 Polycystic ovarian syndrome	0.006	0.994	0.000
E34.9 Endocrine disorder, unspecified	0.005	0.994	0.000
E34.0 Carcinoid syndrome	0.005	0.994	0.001
I24.1 Dressler's syndrome	0.002	0.995	0.003
S82.0 Fracture of patella	0.005	0.995	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.005	0.995	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.004	0.996	0.000
D10.3 Other and unspecified parts of mouth	0.004	0.996	0.000
M89.0 Algoneurodystrophy	0.004	0.996	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.004	0.996	0.000
M89.03 Algoneurodystrophy (Forearm)	0.004	0.996	0.000
S00.0 Superficial injury of scalp	0.004	0.996	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.004	0.996	0.000
M89.04 Algoneurodystrophy (Hand)	0.004	0.996	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.004	0.996	0.000
D33.3 Cranial nerves	0.004	0.996	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.004	0.996	0.000
M89.9 Disorder of bone, unspecified	0.003	0.996	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.003	0.997	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.003	0.997	0.000
D10.0 Lip	0.003	0.997	0.000
R94.3 Abnormal results of cardiovascular function studies	0.003	0.997	0.000
M89.08 Algoneurodystrophy (Other)	0.003	0.997	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.003	0.997	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.003	0.997	0.000
H61.0 Perichondritis of external ear	0.000	0.997	0.003
Z45.0 Adjustment and management of cardiac pacemaker	0.003	0.997	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.003	0.997	0.000
D10 Benign neoplasm of mouth and pharynx	0.003	0.997	0.000
N73.6 Female pelvic peritoneal adhesions	0.003	0.997	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.003	0.997	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.003	0.997	0.000
U80.1 Methicillin resistant agent	0.003	0.997	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.003	0.997	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.003	0.997	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.003	0.997	0.000
W21.9 Unspecified place	0.003	0.997	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.003	0.997	0.000
N73 Other female pelvic inflammatory diseases	0.003	0.997	0.000
S82.01 Fracture of patella (open)	0.003	0.997	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.000	0.997	0.003
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.003	0.997	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.003	0.997	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.003	0.997	0.000
C70 Malignant neoplasm of meninges	0.003	0.997	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.003	0.997	0.000
M00.9 Pyogenic arthritis, unspecified	0.003	0.997	0.000
D10.1 Tongue	0.003	0.997	0.000
N73.8 Other specified female pelvic inflammatory diseases	0.003	0.997	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.003	0.997	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.003	0.997	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.997	0.003
N73.5 Female pelvic peritonitis, unspecified	0.003	0.997	0.000
S02.50 Fracture of tooth (closed)	0.003	0.997	0.000
S82.60 Fracture of lateral malleolus (closed)	0.003	0.997	0.000
D10.6 Nasopharynx	0.003	0.997	0.000
N73.1 Chronic parametritis and pelvic cellulitis	0.003	0.997	0.000
M89.98 Disorder of bone, unspecified (Other)	0.003	0.997	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.003	0.997	0.000
A49.0 Staphylococcal infection, unspecified	0.000	0.997	0.003
O70.2 Third degree perineal laceration during delivery	0.000	0.997	0.003
M00.94 Pyogenic arthritis, unspecified (Hand)	0.003	0.997	0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.003	0.997	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.997	0.003
D10.7 Hypopharynx	0.002	0.997	0.000
D10.2 Floor of mouth	0.002	0.997	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
C72.0 Spinal cord	0.002	0.997	0.000
D10.9 Pharynx, unspecified	0.002	0.997	0.000
F20.9 Schizophrenia, unspecified	0.000	0.997	0.003
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.003	0.997	0.000
H61.1 Non-infective disorders of pinna	0.000	0.997	0.002
H61 Other disorders of external ear	0.000	0.997	0.003
D10.4 Tonsil	0.002	0.997	0.000
C72.9 Central nervous system, unspecified	0.002	0.997	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.002	0.997	0.000
C72.5 Other and unspecified cranial nerves	0.002	0.997	0.000
C72.4 Acoustic nerve	0.002	0.997	0.000
C72.3 Optic nerve	0.002	0.997	0.000
C72.2 Olfactory nerve	0.002	0.997	0.000
C72.1 Cauda equina	0.002	0.997	0.000
N73.4 Female chronic pelvic peritonitis	0.002	0.998	0.000
N73.3 Female acute pelvic peritonitis	0.002	0.998	0.000
N73.2 Unspecified parametritis and pelvic cellulitis	0.002	0.998	0.000
N73.0 Acute parametritis and pelvic cellulitis	0.002	0.998	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.002	0.998	0.000
Y83.9 Surgical procedure, unspecified	0.002	0.998	0.000
D10.5 Other parts of oropharynx	0.002	0.998	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
C70.9 Meninges, unspecified	0.002	0.998	0.000
C70.1 Spinal meninges	0.002	0.998	0.000
G35 Multiple sclerosis	0.002	0.998	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.998	0.002
M89.91 Disorder of bone, unspecified (Shoulder region)	0.002	0.998	0.000
H61.2 Impacted cerumen	0.000	0.998	0.002
M00.98 Pyogenic arthritis, unspecified (Other)	0.002	0.998	0.000
H61.9 Disorder of external ear, unspecified	0.000	0.998	0.002
S82.6 Fracture of lateral malleolus	0.002	0.998	0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.002	0.998	0.000
C70.0 Cerebral meninges	0.002	0.998	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.002	0.998	0.000
S60.8 Other superficial injuries of wrist and hand	0.002	0.998	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.002	0.998	0.000
C69 Malignant neoplasm of eye and adnexa	0.002	0.998	0.000
M89 Other disorders of bone	0.002	0.998	0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.002	0.998	0.000
F20.0 Paranoid schizophrenia	0.000	0.998	0.002
N85.0 Endometrial glandular hyperplasia	0.002	0.998	0.000
H61.3 Acquired stenosis of external ear canal	0.000	0.998	0.002
D33.0 Brain, supratentorial	0.002	0.998	0.000
S82.61 Fracture of lateral malleolus (open)	0.002	0.998	0.000
D33.2 Brain, unspecified	0.002	0.998	0.000
F20 Schizophrenia	0.000	0.998	0.002
D33.4 Spinal cord	0.002	0.998	0.000
F10.4 Withdrawal state with delirium	0.002	0.998	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.002	0.998	0.000
C69.9 Eye, unspecified	0.002	0.998	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.000	0.998	0.002
C69.2 Retina	0.002	0.998	0.000
D33.9 Central nervous system, unspecified	0.002	0.998	0.000
D33.7 Other specified parts of central nervous system	0.002	0.998	0.000
D33.1 Brain, infratentorial	0.002	0.998	0.000
S82.5 Fracture of medial malleolus	0.002	0.998	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.002	0.998	0.000
S82 Fracture of lower leg, including ankle	0.002	0.998	0.000
S82.51 Fracture of medial malleolus (open)	0.002	0.998	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.002	0.998	0.000
C69.8 Overlapping lesion of eye and adnexa	0.002	0.998	0.000
C69.5 Lachrymal gland and duct	0.002	0.998	0.000
C69.4 Ciliary body	0.002	0.998	0.000
C69.1 Cornea	0.002	0.998	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.002	0.998	0.000
M89.6 Osteopathy after poliomyelitis	0.002	0.998	0.000
M89.2 Other disorders of bone development and growth	0.002	0.998	0.000
M89.1 Epiphyseal arrest	0.002	0.998	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.998	0.002
L03.8 Cellulitis of other sites	0.002	0.998	0.000
S60 Superficial injury of wrist and hand	0.002	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.998	0.002
E16.2 Hypoglycaemia, unspecified	0.002	0.998	0.000
L29.9 Pruritus, unspecified	0.000	0.998	0.002
W08.0 Home	0.002	0.998	0.000
C69.6 Orbit	0.001	0.998	0.000
F20.8 Other schizophrenia	0.000	0.998	0.002
I49.9 Cardiac arrhythmia, unspecified	0.002	0.998	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.998	0.002
M85.0 Fibrous dysplasia (monostotic)	0.002	0.998	0.000
M00 Pyogenic arthritis	0.002	0.998	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.998	0.002
D03.5 Melanoma in situ of trunk	0.000	0.998	0.002
F20.6 Simple schizophrenia	0.000	0.998	0.002
F20.5 Residual schizophrenia	0.000	0.998	0.002
F20.4 Postschizophrenic depression	0.000	0.998	0.002
F20.3 Undifferentiated schizophrenia	0.000	0.998	0.002
F20.1 Hebephrenic schizophrenia	0.000	0.998	0.002
I35.9 Aortic valve disorder, unspecified	0.002	0.998	0.000
E16 Other disorders of pancreatic internal secretion	0.002	0.998	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.002	0.998	0.000
M43.06 Spondylolysis (Lumbar region)	0.000	0.998	0.002
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
W05.0 Home	0.002	0.998	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
C69.0 Conjunctiva	0.001	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.001	0.998	0.000
R49.8 Other and unspecified voice disturbances	0.002	0.998	0.000
S82.9 Fracture of lower leg, part unspecified	0.002	0.998	0.000
S82.7 Multiple fractures of lower leg	0.002	0.998	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.001	0.998	0.000
S60.2 Contusion of other parts of wrist and hand	0.002	0.998	0.000
Z90.1 Acquired absence of breast(s)	0.000	0.998	0.002
M89.5 Osteolysis	0.001	0.998	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.001	0.998	0.000
M89.18 Epiphyseal arrest (Other)	0.001	0.998	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.001	0.998	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.001	0.998	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.001	0.998	0.000
M89.14 Epiphyseal arrest (Hand)	0.001	0.998	0.000
M89.13 Epiphyseal arrest (Forearm)	0.001	0.998	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.001	0.998	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.001	0.998	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.001	0.998	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.001	0.998	0.000
M89.28 Other disorders of bone development and growth (Other)	0.001	0.998	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.001	0.998	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.001	0.998	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.001	0.998	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.001	0.998	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.001	0.998	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.001	0.998	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.001	0.998	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.001	0.998	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.001	0.998	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.001	0.998	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.001	0.998	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.001	0.998	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.001	0.998	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.001	0.998	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.001	0.998	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.001	0.998	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.001	0.998	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.001	0.998	0.000
F20.2 Catatonic schizophrenia	0.000	0.998	0.001
Y48.3 Local anaesthetics	0.002	0.998	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.002	0.998	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
D51 Vitamin B12 deficiency anaemia	0.002	0.998	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.998	0.001
M79.67 Pain in limb (Ankle and foot)	0.000	0.998	0.002
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.998	0.002
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
S60.1 Contusion of finger(s) with damage to nail	0.001	0.998	0.000
M00.0 Staphylococcal arthritis and polyarthritis	0.001	0.998	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.001	0.998	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.001	0.998	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.001	0.998	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.001	0.998	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.001	0.998	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.001	0.998	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.001	0.998	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.001	0.998	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.001	0.998	0.000
S72.00 Fracture of neck of femur (closed)	0.000	0.998	0.002
M80.9 Unspecified osteoporosis with pathological fracture	0.001	0.998	0.000
N82.3 Fistula of vagina to large intestine	0.002	0.998	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.001	0.998	0.000
M62.88 Other specified disorders of muscle (Other)	0.000	0.998	0.001
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.001	0.998	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.001	0.998	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.001	0.998	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.001	0.998	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.001	0.998	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.001	0.998	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.001	0.998	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.001	0.998	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.001	0.998	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.001	0.998	0.000
E16.4 Abnormal secretion of gastrin	0.001	0.998	0.000
E16.3 Increased secretion of glucagon	0.001	0.998	0.000
E16.1 Other hypoglycaemia	0.001	0.998	0.000
I35.0 Aortic (valve) stenosis	0.002	0.998	0.000
K80.4 Calculus of bile duct with cholecystitis	0.002	0.998	0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.001	0.998	0.000
M00.2 Other streptococcal arthritis and polyarthritis	0.001	0.998	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.001	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.000	0.999	0.001
M89.3 Hypertrophy of bone	0.001	0.999	0.000
O70.9 Perineal laceration during delivery, unspecified	0.000	0.999	0.001
M00.01 Staphylococcal arthritis and polyarthritis (Shoulder region)	0.001	0.999	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.999	0.001
M21.76 Unequal limb length (acquired) (Lower leg)	0.000	0.999	0.001
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.001	0.999	0.000
R52.2 Other chronic pain	0.001	0.999	0.000
S82.71 Multiple fractures of lower leg (open)	0.001	0.999	0.000
S82.70 Multiple fractures of lower leg (closed)	0.001	0.999	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.001	0.999	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.001	0.999	0.000
A49.8 Other bacterial infections of unspecified site	0.000	0.999	0.001
J86.9 Pyothorax without fistula	0.001	0.999	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.001	0.999	0.000
M89.59 Osteolysis (Site unspecified)	0.001	0.999	0.000
M89.58 Osteolysis (Other)	0.001	0.999	0.000
M89.57 Osteolysis (Ankle and foot)	0.001	0.999	0.000
M89.56 Osteolysis (Lower leg)	0.001	0.999	0.000
M89.54 Osteolysis (Hand)	0.001	0.999	0.000
M89.53 Osteolysis (Forearm)	0.001	0.999	0.000
M89.52 Osteolysis (Upper arm)	0.001	0.999	0.000
M89.51 Osteolysis (Shoulder region)	0.001	0.999	0.000
M89.50 Osteolysis (Multiple sites)	0.001	0.999	0.000
B37.0 Candidal stomatitis	0.001	0.999	0.000
E07.9 Disorder of thyroid, unspecified	0.001	0.999	0.000
M21.6 Other acquired deformities of ankle and foot	0.000	0.999	0.001
E21.0 Primary hyperparathyroidism	0.001	0.999	0.000
E85.9 Amyloidosis, unspecified	0.000	0.999	0.001
D51.8 Other vitamin B12 deficiency anaemias	0.001	0.999	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.001	0.999	0.000
D51.2 Transcobalamin II deficiency	0.001	0.999	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.001	0.999	0.000
K14.9 Disease of tongue, unspecified	0.000	0.999	0.001
W21 Striking against or struck by sports equipment	0.001	0.999	0.000
M00.09 Staphylococcal arthritis and polyarthritis (Site unspecified)	0.001	0.999	0.000
M00.08 Staphylococcal arthritis and polyarthritis (Other)	0.001	0.999	0.000
M00.07 Staphylococcal arthritis and polyarthritis (Ankle and foot)	0.001	0.999	0.000
M00.05 Staphylococcal arthritis and polyarthritis (Pelvic region and thigh)	0.001	0.999	0.000
M00.04 Staphylococcal arthritis and polyarthritis (Hand)	0.001	0.999	0.000
M00.03 Staphylococcal arthritis and polyarthritis (Forearm)	0.001	0.999	0.000
M00.02 Staphylococcal arthritis and polyarthritis (Upper arm)	0.001	0.999	0.000
M00.00 Staphylococcal arthritis and polyarthritis (Multiple sites)	0.001	0.999	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.999	0.001
Y83.4 Other reconstructive surgery	0.000	0.999	0.001
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M00.19 Pneumococcal arthritis and polyarthritis (Site unspecified)	0.001	0.999	0.000
M00.18 Pneumococcal arthritis and polyarthritis (Other)	0.001	0.999	0.000
M00.17 Pneumococcal arthritis and polyarthritis (Ankle and foot)	0.001	0.999	0.000
M00.16 Pneumococcal arthritis and polyarthritis (Lower leg)	0.001	0.999	0.000
M00.15 Pneumococcal arthritis and polyarthritis (Pelvic region and thigh)	0.001	0.999	0.000
M00.14 Pneumococcal arthritis and polyarthritis (Hand)	0.001	0.999	0.000
M00.13 Pneumococcal arthritis and polyarthritis (Forearm)	0.001	0.999	0.000
M00.12 Pneumococcal arthritis and polyarthritis (Upper arm)	0.001	0.999	0.000
M00.11 Pneumococcal arthritis and polyarthritis (Shoulder region)	0.001	0.999	0.000
M00.10 Pneumococcal arthritis and polyarthritis (Multiple sites)	0.001	0.999	0.000
M00.29 Other streptococcal arthritis and polyarthritis (Site unspecified)	0.001	0.999	0.000
M00.28 Other streptococcal arthritis and polyarthritis (Other)	0.001	0.999	0.000
M00.27 Other streptococcal arthritis and polyarthritis (Ankle and foot)	0.001	0.999	0.000
M00.26 Other streptococcal arthritis and polyarthritis (Lower leg)	0.001	0.999	0.000
M00.25 Other streptococcal arthritis and polyarthritis (Pelvic region and thigh)	0.001	0.999	0.000
M00.24 Other streptococcal arthritis and polyarthritis (Hand)	0.001	0.999	0.000
M00.23 Other streptococcal arthritis and polyarthritis (Forearm)	0.001	0.999	0.000
M00.22 Other streptococcal arthritis and polyarthritis (Upper arm)	0.001	0.999	0.000
M00.21 Other streptococcal arthritis and polyarthritis (Shoulder region)	0.001	0.999	0.000
M00.20 Other streptococcal arthritis and polyarthritis (Multiple sites)	0.001	0.999	0.000
M00.89 Arthritis and polyarthritis due to other specified bacterial agents (Site unspecified)	0.001	0.999	0.000
M00.88 Arthritis and polyarthritis due to other specified bacterial agents (Other)	0.001	0.999	0.000
M00.87 Arthritis and polyarthritis due to other specified bacterial agents (Ankle and foot)	0.001	0.999	0.000
M00.86 Arthritis and polyarthritis due to other specified bacterial agents (Lower leg)	0.001	0.999	0.000
M00.85 Arthritis and polyarthritis due to other specified bacterial agents (Pelvic region and thigh)	0.001	0.999	0.000
M00.84 Arthritis and polyarthritis due to other specified bacterial agents (Hand)	0.001	0.999	0.000
M00.83 Arthritis and polyarthritis due to other specified bacterial agents (Forearm)	0.001	0.999	0.000
M00.82 Arthritis and polyarthritis due to other specified bacterial agents (Upper arm)	0.001	0.999	0.000
M00.81 Arthritis and polyarthritis due to other specified bacterial agents (Shoulder region)	0.001	0.999	0.000
M00.80 Arthritis and polyarthritis due to other specified bacterial agents (Multiple sites)	0.001	0.999	0.000
F25.0 Schizoaffective disorder, manic type	0.000	0.999	0.001
K26.4 Chronic or unspecified with haemorrhage	0.001	0.999	0.000
M21.4 Flat foot [pes planus] (acquired)	0.000	0.999	0.001
S02.5 Fracture of tooth	0.001	0.999	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.000	0.999	0.001
M89.39 Hypertrophy of bone (Site unspecified)	0.001	0.999	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.001	0.999	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.001	0.999	0.000
M89.34 Hypertrophy of bone (Hand)	0.001	0.999	0.000
M89.33 Hypertrophy of bone (Forearm)	0.001	0.999	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.001	0.999	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.001	0.999	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.001	0.999	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.001	0.999	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.001	0.999	0.000
L03.9 Cellulitis, unspecified	0.000	0.999	0.001
S60.0 Contusion of finger(s) without damage to nail	0.001	0.999	0.000
T39.0 Salicylates	0.001	0.999	0.000
M00.06 Staphylococcal arthritis and polyarthritis (Lower leg)	0.001	0.999	0.000
H61.8 Other specified disorders of external ear	0.000	0.999	0.001
M21.7 Unequal limb length (acquired)	0.000	0.999	0.001
S82.1 Fracture of upper end of tibia	0.001	0.999	0.000
M21.1 Varus deformity, not elsewhere classified	0.000	0.999	0.001
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.999	0.001
T36.0 Penicillins	0.000	0.999	0.001
T63.4 Venom of other arthropods	0.001	0.999	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.999	0.001
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.999	0.001
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.999	0.001
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.999	0.001
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.999	0.001
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.999	0.001
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.999	0.001
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations