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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs601338
log Bayes Factor = 26.5485
Chromosome 19   position 49,206,674  (GRCh37) Explore rs601338 on Ensembl!
Variant rs601338 is listed in the   GWAS Catalog   ⇪
Variant rs601338 is part of Cluster X0338

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K80.1 Calculus of gallbladder with other cholecystitis
0.000 0.000 1.000
K80 Cholelithiasis
0.000 0.000 1.000
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.000 1.000
K29 Gastritis and duodenitis
0.000 0.000 1.000
K26 Duodenal ulcer
0.000 0.000 1.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.000 0.000 1.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.000 1.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.000 1.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.000 0.000 1.000
K29.8 Duodenitis
0.000 0.001 0.999
E78.0 Pure hypercholesterolaemia
0.000 0.001 0.999
Chapter XI Diseases of the digestive system
0.000 0.002 0.998
K82 Other diseases of gallbladder
0.000 0.002 0.998
K65-K67 Diseases of peritoneum
0.000 0.012 0.988
K82.8 Other specified diseases of gallbladder
0.000 0.018 0.982
K29.0 Acute haemorrhagic gastritis
0.000 0.022 0.978
K29.5 Chronic gastritis, unspecified
0.000 0.025 0.975
K82.4 Cholesterolosis of gallbladder
0.000 0.032 0.968
K29.4 Chronic atrophic gastritis
0.000 0.045 0.955
K65 Peritonitis
0.000 0.047 0.953
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.052 0.948
K66 Other disorders of peritoneum
0.000 0.068 0.932
K82.9 Disease of gallbladder, unspecified
0.000 0.069 0.931
I80 Phlebitis and thrombophlebitis
0.000 0.079 0.921
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.000 0.082 0.918
K83 Other diseases of biliary tract
0.000 0.082 0.918
K31 Other diseases of stomach and duodenum
0.000 0.083 0.917
K26.7 Chronic without haemorrhage or perforation
0.000 0.089 0.911
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.089 0.911
I83 Varicose veins of lower extremities
0.000 0.092 0.908
K26.4 Chronic or unspecified with haemorrhage
0.000 0.094 0.906
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.096 0.904
K83.1 Obstruction of bile duct
0.000 0.107 0.893
K65.8 Other peritonitis
0.000 0.116 0.884
K66.0 Peritoneal adhesions
0.000 0.121 0.879
K31.8 Other specified diseases of stomach and duodenum
0.000 0.125 0.875
K66.8 Other specified disorders of peritoneum
0.000 0.138 0.862
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.166 0.834
K26.1 Acute with perforation
0.000 0.171 0.829
K29.3 Chronic superficial gastritis
0.000 0.172 0.828
K31.9 Disease of stomach and duodenum, unspecified
0.000 0.180 0.820
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.186 0.814
K27 Peptic ulcer, site unspecified
0.000 0.186 0.813
I10-I15 Hypertensive diseases
0.000 0.188 0.812
K83.0 Cholangitis
0.000 0.196 0.804
K29.2 Alcoholic gastritis
0.000 0.197 0.803
K65.0 Acute peritonitis
0.000 0.203 0.797
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.214 0.786
K65.9 Peritonitis, unspecified
0.000 0.217 0.783
K23 Disorders of oesophagus in diseases classified elsewhere
0.000 0.219 0.781
Chapter IX Diseases of the circulatory system
0.000 0.231 0.769
K26.2 Acute with both haemorrhage and perforation
0.000 0.249 0.751
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.249 0.751
K80.8 Other cholelithiasis
0.000 0.257 0.743
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.265 0.735
K31.4 Gastric diverticulum
0.000 0.269 0.731
K80.3 Calculus of bile duct with cholangitis
0.000 0.283 0.717
K29.9 Gastroduodenitis, unspecified
0.000 0.283 0.717
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.283 0.717
I88 Nonspecific lymphadenitis
0.000 0.289 0.711
K31.2 Hourglass stricture and stenosis of stomach
0.000 0.290 0.710
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.291 0.708
K83.9 Disease of biliary tract, unspecified
0.000 0.300 0.700
K90-K93 Other diseases of the digestive system
0.000 0.315 0.685
K31.3 Pylorospasm, not elsewhere classified
0.000 0.318 0.682
I85 Oesophageal varices
0.000 0.322 0.678
K31.0 Acute dilatation of stomach
0.000 0.329 0.671
K28 Gastrojejunal ulcer
0.000 0.330 0.670
K82.3 Fistula of gallbladder
0.000 0.330 0.670
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.331 0.669
K83.5 Biliary cyst
0.000 0.342 0.658
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.342 0.658
K31.1 Adult hypertrophic pyloric stenosis
0.000 0.343 0.657
K27.7 Chronic without haemorrhage or perforation
0.000 0.364 0.636
K66.9 Disorder of peritoneum, unspecified
0.000 0.368 0.632
I26 Pulmonary embolism
0.000 0.370 0.630
K70-K77 Diseases of liver
0.000 0.371 0.629
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.371 0.629
I15 Secondary hypertension
0.000 0.375 0.625
K82.0 Obstruction of gallbladder
0.000 0.375 0.625
K26.3 Acute without haemorrhage or perforation
0.000 0.375 0.625
K23.8 Disorders of oesophagus in other diseases classified elsewhere
0.000 0.376 0.623
K26.0 Acute with haemorrhage
0.000 0.380 0.620
K31.6 Fistula of stomach and duodenum
0.000 0.382 0.618
K25 Gastric ulcer
0.000 0.385 0.615
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.387 0.613
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.402 0.598
K82.2 Perforation of gallbladder
0.000 0.404 0.596
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.410 0.590
K83.2 Perforation of bile duct
0.000 0.412 0.588
K82.1 Hydrops of gallbladder
0.000 0.416 0.584
K26.5 Chronic or unspecified with perforation
0.000 0.416 0.584
K27.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.417 0.583
K27.5 Chronic or unspecified with perforation
0.000 0.417 0.583
K27.4 Chronic or unspecified with haemorrhage
0.000 0.417 0.583
K27.2 Acute with both haemorrhage and perforation
0.000 0.417 0.583
K27.1 Acute with perforation
0.000 0.417 0.583
K27.0 Acute with haemorrhage
0.000 0.417 0.583
K91.4 Colostomy and enterostomy malfunction
0.000 0.426 0.574
K70 Alcoholic liver disease
0.000 0.436 0.564
I13 Hypertensive heart and renal disease
0.000 0.437 0.562
K23.1 Megaoesophagus in Chagas' disease
0.000 0.440 0.560
K23.0 Tuberculous oesophagitis
0.000 0.440 0.560
K50-K52 Noninfective enteritis and colitis
0.000 0.441 0.559
K25.3 Acute without haemorrhage or perforation
0.000 0.442 0.558
K27.3 Acute without haemorrhage or perforation
0.000 0.443 0.557
K83.3 Fistula of bile duct
0.000 0.446 0.554
K83.4 Spasm of sphincter of Oddi
0.000 0.448 0.552
K70.3 Alcoholic cirrhosis of liver
0.000 0.450 0.550
I82 Other venous embolism and thrombosis
0.000 0.450 0.550
I86 Varicose veins of other sites
0.000 0.451 0.549
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.453 0.547
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.453 0.547
I85.9 Oesophageal varices without bleeding
0.000 0.465 0.535
I88.8 Other nonspecific lymphadenitis
0.000 0.469 0.531
K73 Chronic hepatitis, not elsewhere classified
0.000 0.471 0.529
I28 Other diseases of pulmonary vessels
0.000 0.473 0.527
I87 Other disorders of veins
0.000 0.474 0.526
I15.9 Seconday hypertension, unspecified
0.000 0.474 0.526
I00-I02 Acute rheumatic fever
0.000 0.483 0.517
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction
0.000 0.486 0.514
K87.1 Disorders of pancreas in diseases classified elsewhere
0.000 0.486 0.514
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere
0.000 0.486 0.514
K50 Crohn's disease [regional enteritis]
0.000 0.490 0.510
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.490 0.510
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.492 0.508
K67.3 Tuberculous peritonitis
0.000 0.492 0.508
K67.2 Syphilitic peritonitis
0.000 0.492 0.508
K67.1 Gonococcal peritonitis
0.000 0.492 0.508
K67.0 Chlamydial peritonitis
0.000 0.492 0.508
K29.1 Other acute gastritis
0.000 0.498 0.502
K50.1 Crohn's disease of large intestine
0.000 0.501 0.499
K74 Fibrosis and cirrhosis of liver
0.000 0.501 0.499
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.507 0.493
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.509 0.491
K91.1 Postgastric surgery syndromes
0.000 0.511 0.489
K28.7 Chronic without haemorrhage or perforation
0.000 0.519 0.480
K28.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.519 0.480
K28.5 Chronic or unspecified with perforation
0.000 0.519 0.480
K28.4 Chronic or unspecified with haemorrhage
0.000 0.519 0.480
K28.3 Acute without haemorrhage or perforation
0.000 0.519 0.480
K28.2 Acute with both haemorrhage and perforation
0.000 0.519 0.480
K28.1 Acute with perforation
0.000 0.519 0.480
K28.0 Acute with haemorrhage
0.000 0.519 0.480
I15.8 Other secondary hypertension
0.000 0.525 0.474
K91.5 Postcholecystectomy syndrome
0.000 0.526 0.474
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.527 0.473
K25.5 Chronic or unspecified with perforation
0.000 0.527 0.473
I86.4 Gastric varices
0.000 0.536 0.464
I85.0 Oesophageal varices with bleeding
0.000 0.538 0.462
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.542 0.458
K25.7 Chronic without haemorrhage or perforation
0.000 0.543 0.457
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.545 0.455
K77 Liver disorders in diseases classified elsewhere
0.000 0.549 0.451
I11 Hypertensive heart disease
0.000 0.550 0.450
I15.2 Hypertension secondary to endocrine disorders
0.000 0.552 0.448
K73.9 Chronic hepatitis, unspecified
0.000 0.553 0.447
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.554 0.446
I28.8 Other specified diseases of pulmonary vessels
0.000 0.558 0.441
K25.2 Acute with both haemorrhage and perforation
0.000 0.559 0.441
K25.1 Acute with perforation
0.000 0.559 0.441
K85 Acute pancreatitis
0.000 0.563 0.437
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.567 0.433
I82.0 Budd-Chiari syndrome
0.000 0.570 0.430
I15.1 Hypertension secondary to other renal disorders
0.000 0.574 0.426
K25.0 Acute with haemorrhage
0.000 0.577 0.423
K91.3 Postoperative intestinal obstruction
0.000 0.577 0.423
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.578 0.422
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.590 0.410
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.591 0.408
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.592 0.408
K25.4 Chronic or unspecified with haemorrhage
0.000 0.592 0.408
I86.2 Pelvic varices
0.000 0.594 0.406
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.596 0.403
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.596 0.403
K72 Hepatic failure, not elsewhere classified
0.000 0.596 0.403
K74.5 Biliary cirrhosis, unspecified
0.000 0.600 0.400
K74.0 Hepatic fibrosis
0.000 0.601 0.399
K31.5 Obstruction of duodenum
0.000 0.605 0.395
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.605 0.395
I82.1 Thrombophlebitis migrans
0.000 0.606 0.394
I86.0 Sublingual varices
0.000 0.606 0.393
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.607 0.393
K50.8 Other Crohn's disease
0.000 0.608 0.392
K74.6 Other and unspecified cirrhosis of liver
0.000 0.608 0.392
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.611 0.389
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.615 0.384
K80.4 Calculus of bile duct with cholecystitis
0.000 0.616 0.384
I81 Portal vein thrombosis
0.000 0.618 0.382
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.618 0.382
I82.2 Embolism and thrombosis of vena cava
0.000 0.620 0.380
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.621 0.379
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.621 0.379
I28.1 Aneurysm of pulmonary artery
0.000 0.622 0.378
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.622 0.378
I87.0 Postphlebitic syndrome
0.000 0.623 0.377
I15.0 Renovascular hypertension
0.000 0.624 0.376
I86.8 Varicose veins of other specified sites
0.000 0.629 0.371
I02 Rheumatic chorea
0.000 0.629 0.371
I01 Rheumatic fever with heart involvement
0.000 0.629 0.371
K70.4 Alcoholic hepatic failure
0.000 0.631 0.369
I82.3 Embolism and thrombosis of renal vein
0.000 0.637 0.363
K74.1 Hepatic sclerosis
0.000 0.638 0.362
K92 Other diseases of digestive system
0.000 0.639 0.361
I86.3 Vulval varices
0.000 0.641 0.359
K85.9 Acute pancreatitis, unspecified
0.000 0.642 0.358
K74.4 Secondary biliary cirrhosis
0.000 0.642 0.358
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.642 0.358
I72 Other aneurysm
0.000 0.647 0.353
I89.1 Lymphangitis
0.000 0.647 0.353
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.648 0.352
K93.1 Megacolon in Chagas' disease
0.000 0.648 0.352
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.648 0.352
I74 Arterial embolism and thrombosis
0.000 0.650 0.350
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.652 0.348
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.652 0.348
I70 Atherosclerosis
0.000 0.655 0.345
K70.1 Alcoholic hepatitis
0.000 0.657 0.343
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.658 0.341
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.659 0.341
I00 Rheumatic fever without mention of heart involvement
0.000 0.663 0.337
I87.9 Disorder of vein, unspecified
0.000 0.664 0.336
K71 Toxic liver disease
0.000 0.668 0.331
K70.0 Alcoholic fatty liver
0.000 0.670 0.330
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.670 0.330
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.674 0.326
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.676 0.324
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.676 0.324
K76 Other diseases of liver
0.000 0.676 0.324
K85.8 Other acute pancreatitis
0.000 0.684 0.316
I72.4 Aneurysm of artery of lower extremity
0.000 0.693 0.307
K35-K38 Diseases of appendix
0.000 0.694 0.306
K72.9 Hepatic failure, unspecified
0.000 0.695 0.305
K29.6 Other gastritis
0.000 0.696 0.304
I70.0 Atherosclerosis of aorta
0.000 0.700 0.300
I12 Hypertensive renal disease
0.000 0.703 0.297
K92.0 Haematemesis
0.000 0.707 0.293
I71 Aortic aneurysm and dissection
0.000 0.709 0.291
K91.2 Postsurgical malabsorption, not elsewhere classified
0.001 0.709 0.290
K76.8 Other specified diseases of liver
0.000 0.712 0.288
K70.9 Alcoholic liver disease, unspecified
0.000 0.714 0.286
K85.3 Drug-induced acute pancreatitis
0.000 0.719 0.281
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.720 0.280
I72.0 Aneurysm of carotid artery
0.000 0.721 0.279
I70.1 Atherosclerosis of renal artery
0.000 0.721 0.279
I72.9 Aneurysm of unspecified site
0.000 0.722 0.277
I74.5 Embolism and thrombosis of iliac artery
0.000 0.724 0.276
K85.0 Idiopathic acute pancreatitis
0.000 0.725 0.275
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.725 0.275
K72.0 Acute and subacute hepatic failure
0.000 0.725 0.275
I82.8 Embolism and thrombosis of other specified veins
0.000 0.726 0.274
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.728 0.272
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.729 0.271
I87.1 Compression of vein
0.000 0.730 0.270
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.733 0.267
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.734 0.266
I01.8 Other acute rheumatic heart disease
0.000 0.734 0.266
I01.2 Acute rheumatic myocarditis
0.000 0.734 0.266
I01.1 Acute rheumatic endocarditis
0.000 0.734 0.266
I01.0 Acute rheumatic pericarditis
0.000 0.734 0.266
I02.9 Rheumatic chorea without heart involvement
0.000 0.734 0.266
I02.0 Rheumatic chorea with heart involvement
0.000 0.734 0.266
K50.9 Crohn's disease, unspecified
0.000 0.734 0.266
K52 Other non-infective gastro-enteritis and colitis
0.000 0.734 0.266
I72.2 Aneurysm of renal artery
0.000 0.735 0.265
K92.2 Gastro-intestinal haemorrhage, unspecified
0.000 0.737 0.263
K66.1 Haemoperitoneum
0.002 0.738 0.260
I87.8 Other specified disorders of veins
0.000 0.743 0.257
K83.8 Other specified diseases of biliary tract
0.000 0.745 0.255
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.747 0.253
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.747 0.253
I72.3 Aneurysm of iliac artery
0.000 0.751 0.249
I60-I69 Cerebrovascular diseases
0.000 0.751 0.249
E53.8 Deficiency of other specified B group vitamins
0.248 0.752 0.000
I70.9 Generalised and unspecified atherosclerosis
0.000 0.752 0.248
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.755 0.245
I99 Other and unspecified disorders of circulatory system
0.000 0.758 0.242
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.759 0.241
K74.3 Primary biliary cirrhosis
0.000 0.759 0.240
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.760 0.240
K71.9 Toxic liver disease, unspecified
0.000 0.762 0.238
K71.8 Toxic liver disease with other disorders of liver
0.000 0.762 0.238
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.762 0.238
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.762 0.238
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.762 0.238
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.762 0.238
K71.2 Toxic liver disease with acute hepatitis
0.000 0.762 0.238
K72.1 Chronic hepatic failure
0.000 0.763 0.237
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.766 0.234
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.766 0.234
I98.0 Cardiovascular syphilis
0.000 0.766 0.234
K85.1 Biliary acute pancreatitis
0.000 0.767 0.233
K76.5 Hepatic veno-occlusive disease
0.000 0.768 0.232
K76.4 Peliosis hepatis
0.000 0.768 0.232
K76.3 Infarction of liver
0.000 0.768 0.232
K76.2 Central haemorrhagic necrosis of liver
0.000 0.768 0.232
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.769 0.231
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.770 0.230
K76.1 Chronic passive congestion of liver
0.000 0.770 0.230
I89.0 Lymphoedema, not elsewhere classified
0.000 0.771 0.229
I61 Intracerebral haemorrhage
0.000 0.771 0.229
K71.0 Toxic liver disease with cholestasis
0.000 0.772 0.227
I72.8 Aneurysm of other specified arteries
0.000 0.774 0.226
K76.7 Hepatorenal syndrome
0.000 0.776 0.224
K40-K46 Hernia
0.000 0.778 0.222
K92.1 Melaena
0.000 0.778 0.222
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.778 0.222
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.781 0.219
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.782 0.218
K90 Intestinal malabsorption
0.000 0.784 0.216
K36 Other appendicitis
0.000 0.784 0.216
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.784 0.216
I72.1 Aneurysm of artery of upper extremity
0.000 0.784 0.215
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.785 0.215
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.785 0.215
K52.3 Indeterminate colitis
0.000 0.786 0.214
I27 Other pulmonary heart diseases
0.000 0.787 0.213
I70.8 Atherosclerosis of other arteries
0.000 0.789 0.211
I95 Hypotension
0.000 0.789 0.211
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.791 0.209
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.791 0.209
K92.8 Other specified diseases of digestive system
0.000 0.792 0.208
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.793 0.207
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.794 0.206
K71.1 Toxic liver disease with hepatic necrosis
0.001 0.795 0.205
K52.1 Toxic gastro-enteritis and colitis
0.000 0.798 0.202
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.799 0.201
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.800 0.200
K50.0 Crohn's disease of small intestine
0.000 0.801 0.199
K85.2 Alcohol-induced acute pancreatitis
0.001 0.802 0.197
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.803 0.197
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.804 0.196
I63 Cerebral infarction
0.000 0.805 0.195
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.808 0.191
K35 Acute appendicitis
0.000 0.808 0.192
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.810 0.190
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.810 0.190
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.810 0.190
I27.9 Pulmonary heart disease, unspecified
0.000 0.811 0.189
K41 Femoral hernia
0.000 0.811 0.189
I86.1 Scrotal varices
0.000 0.811 0.189
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.001 0.812 0.188
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.813 0.187
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.814 0.186
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.815 0.185
K92.9 Disease of digestive system, unspecified
0.000 0.816 0.184
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.817 0.183
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.818 0.182
K46 Unspecified abdominal hernia
0.000 0.819 0.181
I73 Other peripheral vascular diseases
0.000 0.820 0.180
E53 Deficiency of other B group vitamins
0.177 0.821 0.002
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.822 0.178
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.822 0.178
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.823 0.177
I12.9 Hypertensive renal disease without renal failure
0.000 0.823 0.177
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.824 0.176
J98 Other respiratory disorders
0.000 0.824 0.176
I95.2 Hypotension due to drugs
0.000 0.826 0.174
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.826 0.174
I95.0 Idiopathic hypotension
0.000 0.827 0.173
K21 Gastro-oesophageal reflux disease
0.000 0.827 0.173
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.828 0.172
E78.2 Mixed hyperlipidaemia
0.000 0.830 0.170
J98.8 Other specified respiratory disorders
0.000 0.830 0.170
K35.2 Acute appendicitis with generalized peritonitis
0.000 0.830 0.170
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.831 0.169
I69 Sequelae of cerebrovascular disease
0.000 0.831 0.169
I77 Other disorders of arteries and arterioles
0.000 0.831 0.169
J98.1 Pulmonary collapse
0.000 0.832 0.168
K76.9 Liver disease, unspecified
0.000 0.832 0.168
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.834 0.166
I79.1 Aortitis in diseases classified elsewhere
0.000 0.835 0.165
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.835 0.165
K76.6 Portal hypertension
0.000 0.835 0.165
E78.4 Other hyperlipidaemia
0.000 0.836 0.163
K86 Other diseases of pancreas
0.000 0.838 0.162
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.838 0.162
K43 Ventral hernia
0.000 0.839 0.161
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.840 0.160
J95-J99 Other diseases of the respiratory system
0.000 0.840 0.160
I61.8 Other intracerebral haemorrhage
0.000 0.841 0.158
I62 Other nontraumatic intracranial haemorrhage
0.000 0.844 0.156
I65.1 Occlusion and stenosis of basilar artery
0.000 0.844 0.156
K76.0 Fatty (change of) liver, not elsewhere classified
0.000 0.844 0.156
K90.3 Pancreatic steatorrhoea
0.000 0.845 0.155
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.845 0.155
K90.1 Tropical sprue
0.000 0.845 0.155
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.845 0.155
K75 Other inflammatory liver diseases
0.000 0.846 0.154
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.846 0.154
I27.1 Kyphoscoliotic heart disease
0.000 0.847 0.152
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.848 0.151
I69.3 Sequelae of cerebral infarction
0.000 0.848 0.152
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.849 0.151
E78.6 Lipoprotein deficiency
0.000 0.849 0.151
K90.8 Other intestinal malabsorption
0.000 0.849 0.151
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.849 0.151
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.849 0.151
E53.9 Vitamin B deficiency, unspecified
0.149 0.850 0.001
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.852 0.147
J98.2 Interstitial emphysema
0.000 0.853 0.147
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.853 0.146
I71.0 Dissection of aorta [any part]
0.000 0.854 0.146
I60 Subarachnoid haemorrhage
0.000 0.854 0.146
K38 Other diseases of appendix
0.000 0.856 0.144
I95.8 Other hypotension
0.000 0.856 0.144
I05-I09 Chronic rheumatic heart diseases
0.000 0.856 0.144
J98.4 Other disorders of lung
0.000 0.856 0.144
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.857 0.143
I74.8 Embolism and thrombosis of other arteries
0.001 0.857 0.143
J98.9 Respiratory disorder, unspecified
0.000 0.857 0.143
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.859 0.141
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.859 0.141
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.860 0.140
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.860 0.140
I73.9 Peripheral vascular disease, unspecified
0.000 0.860 0.140
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.861 0.139
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.861 0.139
J95.8 Other postprocedural respiratory disorders
0.000 0.861 0.139
K35.1 Acute appendicitis with peritoneal abscess
0.000 0.861 0.139
K35.8 Acute appendicitis, other and unspecified
0.000 0.861 0.139
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.861 0.138
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.862 0.138
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.863 0.137
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.863 0.137
I78 Diseases of capillaries
0.000 0.864 0.136
K43.9 Ventral hernia without obstruction or gangrene
0.000 0.864 0.136
K35.0 Acute appendicitis with generalised peritonitis
0.000 0.864 0.136
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.864 0.136
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.864 0.136
I97.0 Postcardiotomy syndrome
0.000 0.866 0.134
E78.3 Hyperchylomicronaemia
0.000 0.866 0.134
K75.0 Abscess of liver
0.000 0.866 0.134
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.870 0.130
K46.1 Unspecified abdominal hernia with gangrene
0.000 0.870 0.130
J98.5 Diseases of mediastinum, not elsewhere classified
0.000 0.870 0.130
I77.6 Arteritis, unspecified
0.000 0.870 0.130
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.871 0.129
E53.1 Pyridoxine deficiency
0.127 0.871 0.001
E53.0 Riboflavin deficiency
0.127 0.871 0.001
E78.1 Pure hyperglyceridaemia
0.000 0.872 0.128
I11.9 Hypertensive heart disease without (congestive) heart failure
0.001 0.872 0.127
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.872 0.128
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.874 0.126
J98.3 Compensatory emphysema
0.000 0.874 0.126
I77.8 Other specified disorders of arteries and arterioles
0.000 0.874 0.126
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.875 0.125
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.875 0.125
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.875 0.125
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.875 0.125
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.876 0.124
K81 Cholecystitis
0.000 0.876 0.124
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.877 0.123
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.878 0.122
I62.1 Nontraumatic extradural haemorrhage
0.000 0.878 0.122
I73.8 Other specified peripheral vascular diseases
0.000 0.878 0.122
I77.5 Necrosis of artery
0.000 0.879 0.121
I77.4 Coeliac artery compression syndrome
0.000 0.879 0.121
I68.0 Cerebral amyloid angiopathy
0.000 0.879 0.120
K45 Other abdominal hernia
0.000 0.880 0.119
K35.3 Acute appendicitis with localized peritonitis
0.000 0.881 0.119
I77.3 Arterial fibromuscular dysplasia
0.000 0.881 0.119
E78.8 Other disorders of lipoprotein metabolism
0.000 0.882 0.118
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.883 0.117
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.884 0.116
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.884 0.116
K43.7 Other and unspecified ventral hernia with gangrene
0.000 0.884 0.115
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.000 0.884 0.115
K43.5 Parastomal hernia without obstruction or gangrene
0.000 0.884 0.115
K43.4 Parastomal hernia with gangrene
0.000 0.884 0.115
K43.3 Parastomal hernia with obstruction, without gangrene
0.000 0.884 0.115
K43.2 Incisional hernia without obstruction or gangrene
0.000 0.884 0.115
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.885 0.115
I70.80 Atherosclerosis of other arteries (without gangrene)
0.001 0.885 0.115
J96 Respiratory failure, not elsewhere classified
0.000 0.885 0.115
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.885 0.115
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.885 0.115
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.886 0.114
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.886 0.114
J98.6 Disorders of diaphragm
0.000 0.886 0.113
K43.1 Ventral hernia with gangrene
0.000 0.886 0.113
K37 Unspecified appendicitis
0.000 0.887 0.113
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.887 0.113
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.889 0.111
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.889 0.111
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.889 0.111
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.889 0.111
K75.2 Nonspecific reactive hepatitis
0.000 0.889 0.111
K75.1 Phlebitis of portal vein
0.000 0.889 0.111
I63.9 Cerebral infarction, unspecified
0.000 0.889 0.111
K44 Diaphragmatic hernia
0.000 0.891 0.109
J09-J18 Influenza and pneumonia
0.000 0.891 0.109
I95.9 Hypotension, unspecified
0.000 0.891 0.109
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.892 0.108
K38.0 Hyperplasia of appendix
0.000 0.892 0.108
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.892 0.108
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.894 0.106
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.000 0.894 0.106
K38.9 Disease of appendix, unspecified
0.000 0.894 0.106

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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