TreeWAS – Variant ID: rs605949

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.992	0.008
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.991	0.009
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.986	0.014
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.982	0.018
T15-T19 Effects of foreign body entering through natural orifice	0.978	0.022
T50.9 Other and unspecified drugs, medicaments and biological substances	0.978	0.022
T18 Foreign body in alimentary tract	0.967	0.033
T43.2 Other and unspecified antidepressants	0.965	0.035
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.965	0.035
T18.1 Foreign body in oesophagus	0.955	0.045
T46 Poisoning by agents primarily affecting the cardiovascular system	0.947	0.053
S60-S69 Injuries to the wrist and hand	0.946	0.054
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.936	0.064
S90-S99 Injuries to the ankle and foot	0.920	0.080
S60 Superficial injury of wrist and hand	0.917	0.083
T00-T07 Injuries involving multiple body regions	0.905	0.095
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.900	0.100
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.899	0.101
T46.4 Angiotensin-converting-enzyme inhibitors	0.896	0.104
T80 Complications following infusion, transfusion and therapeutic injection	0.888	0.112
T43.0 Tricyclic and tetracyclic antidepressants	0.861	0.139
T43.5 Other and unspecified antipsychotics and neuroleptics	0.857	0.143
S60.9 Superficial injury of wrist and hand, unspecified	0.857	0.143
T85 Complications of other internal prosthetic devices, implants and grafts	0.848	0.152
T86 Failure and rejection of transplanted organs and tissues	0.839	0.161
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.836	0.164
T47.1 Other antacids and anti-gastric-secretion drugs	0.829	0.171
S64 Injury of nerves at wrist and hand level	0.823	0.177
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.822	0.178
T00 Superficial injuries involving multiple body regions	0.821	0.179
T87 Complications peculiar to reattachment and amputation	0.821	0.179
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.821	0.179
S62 Fracture at wrist and hand level	0.818	0.182
S20-S29 Injuries to the thorax	0.813	0.187
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.811	0.189
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.808	0.192
S91 Open wound of ankle and foot	0.807	0.193
T18.0 Foreign body in mouth	0.779	0.221
S96 Injury of muscle and tendon at ankle and foot level	0.778	0.222
T16 Foreign body in ear	0.776	0.224
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.772	0.228
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.771	0.229
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.767	0.233
S66 Injury of muscle and tendon at wrist and hand level	0.766	0.234
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.764	0.236
T43.4 Butyrophenone and thioxanthene neuroleptics	0.761	0.238
S62.3 Fracture of other metacarpal bone	0.751	0.249
S92 Fracture of foot, except ankle	0.746	0.254
S60.2 Contusion of other parts of wrist and hand	0.744	0.256
S60.7 Multiple superficial injuries of wrist and hand	0.741	0.259
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.727	0.272
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.727	0.273
S60.0 Contusion of finger(s) without damage to nail	0.725	0.275
S64.1 Injury of median nerve at wrist and hand level	0.724	0.276
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.722	0.278
T19 Foreign body in genito-urinary tract	0.720	0.280
T43.6 Psychostimulants with abuse potential	0.720	0.280
T83.0 Mechanical complication of urinary (indwelling) catheter	0.719	0.281
T18.9 Foreign body in alimentary tract, part unspecified	0.717	0.283
T88 Other complications of surgical and medical care, not elsewhere classified	0.717	0.283
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.716	0.284
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.716	0.284
T41 Poisoning by anaesthetics and therapeutic gases	0.716	0.284
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.716	0.284
S27 Injury of other and unspecified intrathoracic organs	0.716	0.284
T33-T35 Frostbite	0.711	0.289
T26-T28 Burns and corrosions confined to eye and internal organs	0.711	0.289
T43.9 Psychotropic drug, unspecified	0.711	0.289
T43.8 Other psychotropic drugs, not elsewhere classified	0.711	0.289
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.711	0.289
T86.8 Failure and rejection of other transplanted organs and tissues	0.710	0.290
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.708	0.292
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.708	0.292
S64.0 Injury of ulnar nerve at wrist and hand level	0.708	0.292
T50.8 Diagnostic agents	0.707	0.293
T50.7 Analeptics and opioid receptor antagonists	0.707	0.293
T50.6 Antidotes and chelating agents, not elsewhere classified	0.707	0.293
T50.5 Appetite depressants	0.707	0.293
T50.4 Drugs affecting uric acid metabolism	0.707	0.293
T50.3 Electrolytic, caloric and water-balance agents	0.707	0.293
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.707	0.293
T50.1 Loop [high-ceiling] diuretics	0.707	0.293
T50.0 Mineralocorticoids and their antagonists	0.707	0.293
T79-T79 Certain early complications of trauma	0.704	0.296
T18.5 Foreign body in anus and rectum	0.704	0.296
S62.30 Fracture of other metacarpal bone (closed)	0.702	0.298
T20-T25 Burns and corrosions of external body surface, specified by site	0.701	0.299
T15 Foreign body on external eye	0.701	0.299
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.698	0.302
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.697	0.303
T01 Open wounds involving multiple body regions	0.696	0.304
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.695	0.305
T18.8 Foreign body in other and multiple parts of alimentary tract	0.694	0.306
T18.4 Foreign body in colon	0.694	0.306
T18.3 Foreign body in small intestine	0.694	0.306
T18.2 Foreign body in stomach	0.694	0.306
T00.9 Multiple superficial injuries, unspecified	0.694	0.306
T83.2 Mechanical complication of graft of urinary organ	0.692	0.308
T66-T78 Other and unspecified effects of external causes	0.691	0.309
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.689	0.311
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.689	0.311
S91.2 Open wound of toe(s) with damage to nail	0.689	0.311
T36 Poisoning by systemic antibiotics	0.688	0.312
S64.3 Injury of digital nerve of thumb	0.685	0.315
T86.0 Bone-marrow transplant rejection	0.684	0.316
S69 Other and unspecified injuries of wrist and hand	0.684	0.316
T43.3 Phenothiazine antipsychotics and neuroleptics	0.681	0.319
T83.3 Mechanical complication of intra-uterine contraceptive device	0.680	0.320
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.679	0.321
T46.8 Antivaricose drugs, including sclerosing agents	0.679	0.321
T46.7 Peripheral vasodilators	0.679	0.321
T46.5 Other antihypertensive drugs, not elsewhere classified	0.679	0.321
T46.3 Coronary vasodilators, not elsewhere classified	0.679	0.321
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.679	0.321
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.679	0.321
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.678	0.322
T87.6 Other and unspecified complications of amputation stump	0.678	0.322
S50-S59 Injuries to the elbow and forearm	0.677	0.323
S91.3 Open wound of other parts of foot	0.676	0.324
S68 Traumatic amputation of wrist and hand	0.674	0.326
S65 Injury of blood vessels at wrist and hand level	0.673	0.326
T02 Fractures involving multiple body regions	0.673	0.327
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.673	0.327
S62.6 Fracture of other finger	0.668	0.332
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.667	0.333
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.661	0.339
S98 Traumatic amputation of ankle and foot	0.659	0.340
S97 Crushing injury of ankle and foot	0.659	0.340
S95 Injury of blood vessels at ankle and foot level	0.659	0.340
S94 Injury of nerves at ankle and foot level	0.659	0.340
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.659	0.341
S99 Other and unspecified injuries of ankle and foot	0.658	0.342
S60.1 Contusion of finger(s) with damage to nail	0.658	0.342
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.653	0.347
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.652	0.348
S92.3 Fracture of metatarsal bone	0.652	0.348
T06 Other injuries involving multiple body regions, not elsewhere classified	0.649	0.351
T05 Traumatic amputations involving multiple body regions	0.649	0.351
T04 Crushing injuries involving multiple body regions	0.649	0.351
T03 Dislocations, sprains and strains involving multiple body regions	0.649	0.351
T07 Unspecified multiple injuries	0.649	0.351
S60.8 Other superficial injuries of wrist and hand	0.648	0.352
T87.4 Infection of amputation stump	0.648	0.352
T46.1 Calcium-channel blockers	0.648	0.352
T00.8 Superficial injuries involving other combinations of body regions	0.648	0.352
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.645	0.355
T47.8 Other agents primarily affecting the gastro-intestinal system	0.645	0.355
T47.7 Emetics	0.645	0.355
T47.6 Antidiarrhoeal drugs	0.645	0.355
T47.5 Digestants	0.645	0.355
T47.4 Other laxatives	0.645	0.355
T47.3 Saline and osmotic laxatives	0.645	0.355
T47.2 Stimulant laxatives	0.645	0.355
T47.0 Histamine H(2)-receptor antagonists	0.645	0.355
S20 Superficial injury of thorax	0.641	0.359
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.640	0.360
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.637	0.363
T80.6 Other serum reactions	0.637	0.363
T80.5 Anaphylactic shock due to serum	0.637	0.363
T80.4 Rh incompatibility reaction	0.637	0.363
T80.3 ABO incompatibility reaction	0.637	0.363
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.637	0.363
S62.2 Fracture of first metacarpal bone	0.634	0.365
S90 Superficial injury of ankle and foot	0.633	0.367
S67 Crushing injury of wrist and hand	0.631	0.369
T45.2 Vitamins, not elsewhere classified	0.629	0.371
S96.8 Injury of other muscles and tendons at ankle and foot level	0.625	0.375
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.623	0.377
T45.1 Antineoplastic and immunosuppressive drugs	0.621	0.379
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.619	0.381
T42.0 Hydantoin derivatives	0.616	0.384
S62.8 Fracture of other and unspecified parts of wrist and hand	0.614	0.386
T45.0 Antiallergic and antiemetic drugs	0.614	0.386
S27.1 Traumatic haemothorax	0.611	0.389
T59 Toxic effect of other gases, fumes and vapours	0.609	0.391
T00.2 Superficial injuries involving multiple regions of upper limb(s)	0.609	0.391
T42.4 Benzodiazepines	0.608	0.392
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.608	0.392
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.607	0.393
T86.4 Liver transplant failure and rejection	0.603	0.397
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.603	0.397
S27.2 Traumatic heamopneumothorax	0.602	0.398
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.602	0.398
T86.3 Heart-lung transplant failure and rejection	0.602	0.398
T86.2 Heart transplant failure and rejection	0.602	0.398
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.599	0.401
T42.5 Mixed antiepileptics, not elsewhere classified	0.599	0.401
T42.3 Barbiturates	0.599	0.401
T42.2 Succinimides and oxazolidinediones	0.599	0.401
T17 Foreign body in respiratory tract	0.599	0.401
T63 Toxic effect of contact with venomous animals	0.596	0.404
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.591	0.409
S64.9 Injury of unspecified nerve at wrist and hand level	0.590	0.410
S64.8 Injury of other nerves at wrist and hand level	0.590	0.410
S64.7 Injury of multiple nerves at wrist and hand level	0.590	0.410
T39.4 Antirheumatics, not elsewhere classified	0.590	0.410
T39.2 Pyrazolone derivatives	0.590	0.410
T00.6 Superficial injuries involving multiple regions of upper limb(s) with lower limb(s)	0.588	0.411
T00.1 Superficial injuries involving thorax with abdomen, lower back and pelvis	0.588	0.411
T00.0 Superficial injuries involving head with neck	0.588	0.411
T87.5 Necrosis of amputation stump	0.588	0.411
T87.2 Complications of other reattached body part	0.588	0.411
T87.1 Complications of reattached (part of) lower extremity	0.588	0.411
T87.0 Complications of reattached (part of) upper extremity	0.588	0.411
S62.1 Fracture of other carpal bone(s)	0.587	0.413
S92.30 Fracture of metatarsal bone (closed)	0.585	0.415
S21 Open wound of thorax	0.584	0.415
S62.7 Multiple fractures of fingers	0.583	0.416
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.583	0.417
S26 Injury of heart	0.583	0.417
S25 Injury of blood vessels of thorax	0.583	0.417
S24 Injury of nerves and spinal cord at thorax level	0.583	0.417
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.583	0.417
T45.9 Primarily systemic and haematological agent, unspecified	0.581	0.419
T45.8 Other primarily systemic and haematological agents	0.581	0.419
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.581	0.419
T45.6 Fibrinolysis-affecting drugs	0.581	0.419
T45.4 Iron and its compounds	0.581	0.419
T45.3 Enzymes, not elsewhere classified	0.581	0.419
S91.7 Multiple open wounds of ankle and foot	0.579	0.421
S91.0 Open wound of ankle	0.579	0.421
T25 Burn and corrosion of ankle and foot	0.578	0.422
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.576	0.424
S92.5 Fracture of other toe	0.576	0.424
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.574	0.426
T88.9 Complication of surgical and medical care, unspecified	0.574	0.426
T45.5 Anticoagulants	0.571	0.429
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.571	0.429
S27.3 Other injuries of lung	0.569	0.431
T87.3 Neuroma of amputation stump	0.567	0.432
S10-S19 Injuries to the neck	0.565	0.435
T40.2 Other opioids	0.562	0.438
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.558	0.442
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.558	0.442
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.558	0.442
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.558	0.442
S92.2 Fracture of other tarsal bone(s)	0.557	0.443
T51 Toxic effect of alcohol	0.557	0.443
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.555	0.445
T39.0 Salicylates	0.555	0.445
T65 Toxic effect of other and unspecified substances	0.553	0.446
T62 Toxic effect of other noxious substances eaten as food	0.553	0.446
T61 Toxic effect of noxious substances eaten as seafood	0.553	0.446
T60 Toxic effect of pesticides	0.553	0.446
T57 Toxic effect of other inorganic substances	0.553	0.446
T54 Toxic effect of corrosive substances	0.553	0.446
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.553	0.446
T52 Toxic effect of organic solvents	0.553	0.446
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.553	0.446
T55 Toxic effect of soaps and detergents	0.553	0.446
T70 Effects of air pressure and water pressure	0.552	0.448
S68.0 Traumatic amputation of thumb (complete)(partial)	0.552	0.448
S29 Other and unspecified injuries of thorax	0.550	0.450
T01.8 Open wounds involving other combinations of body regions	0.550	0.450
T86.1 Kidney transplant failure and rejection	0.549	0.451
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.549	0.451
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.549	0.451
T68 Hypothermia	0.547	0.453
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.546	0.454
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.541	0.459
T56 Toxic effect of metals	0.541	0.459
S62.31 Fracture of other metacarpal bone (open)	0.538	0.462
S91.1 Open wound of toe(s) without damage to nail	0.536	0.464
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.535	0.465
S92.9 Fracture of foot, unspecified	0.535	0.465
T19.2 Foreign body in vulva and vagina	0.534	0.465
S62.4 Multiple fractures of metacarpal bones	0.533	0.467
T66 Unspecified effects of radiation	0.533	0.467
S62.0 Fracture of navicular [scaphoid] bone of hand	0.530	0.469
T88.7 Unspecified adverse effect of drug or medicament	0.529	0.471
S20.4 Other superficial injuries of back wall of thorax	0.528	0.472
S62.61 Fracture of other finger (open)	0.526	0.474
S62.60 Fracture of other finger (closed)	0.525	0.475
S20.3 Other superficial injuries of front wall of thorax	0.524	0.476
T42.1 Iminostilbenes	0.523	0.476
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.522	0.478
T21 Burn and corrosion of trunk	0.521	0.479
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.520	0.480
S59 Other and unspecified injuries of forearm	0.520	0.480
T58 Toxic effect of carbon monoxide	0.519	0.481
S92.4 Fracture of great toe	0.519	0.481
S69.7 Multiple injuries of wrist and hand	0.519	0.481
T19.9 Foreign body in genito-urinary tract, part unspecified	0.516	0.484
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.516	0.484
T19.3 Foreign body in uterus [any part]	0.516	0.484
T19.1 Foreign body in bladder	0.516	0.484
T19.0 Foreign body in urethra	0.516	0.484
T88.3 Malignant hyperthermia due to anaesthesis	0.514	0.486
T88.2 Shock due to anaesthesia	0.514	0.486
T88.1 Other complications following immunisation, not elsewhere classified	0.514	0.486
T88.0 Infection following immunisation	0.514	0.486
S56 Injury of muscle and tendon at forearm level	0.514	0.486
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.513	0.486
T37.8 Other specified systemic anti-infectives and antiparasitics	0.513	0.486
T37.5 Antiviral drugs	0.513	0.486
T37.4 Anthelminthics	0.513	0.486
T37.3 Other antiprotozoal drugs	0.513	0.486
T37.2 Antimalarials and drugs acting on other blood protozoa	0.513	0.486
T37.1 Antimycobacterial drugs	0.513	0.486
T37.0 Sulphonamides	0.513	0.486
T41.5 Therapeutic gases	0.513	0.486
T41.4 Anaesthetic, unspecified	0.513	0.486
T41.3 Local anaesthetics	0.513	0.486
T41.2 Other and unspecified general anaesthetics	0.513	0.486
T41.1 Intravenous anaesthetics	0.513	0.486
T41.0 Inhaled anaesthetics	0.513	0.486
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.513	0.486
T48.6 Antiasthmatics, not elsewhere classified	0.513	0.486
T48.5 Anti-common-cold drugs	0.513	0.486
T48.4 Expectorants	0.513	0.486
T48.3 Antitussives	0.513	0.486
T48.2 Other and unspecified agents primarily acting on muscles	0.513	0.486
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.513	0.486
T48.0 Oxytocic drugs	0.513	0.486
T49.9 Topical agent, unspecified	0.513	0.486
T49.8 Other topical agents	0.513	0.486
T49.7 Dental drugs, topically applied	0.513	0.486
T49.6 Otorhinolaryngological drugs and preparations	0.513	0.486
T49.5 Ophthalmological drugs and preparations	0.513	0.486
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.513	0.486
T49.3 Emollients, demulcents and protectants	0.513	0.486
T49.2 Local astringents and local detergents	0.513	0.486
T49.1 Antipruritics	0.513	0.486
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.513	0.486
S27.9 Injury of unspecified intrathoracic organ	0.513	0.487
S27.8 Injury of other specified intrathoracic organs	0.513	0.487
S27.7 Multiple injuries of intrathoracic organs	0.513	0.487
S27.6 Injury of pleura	0.513	0.487
S27.5 Injury of thoracic trachea	0.513	0.487
S27.4 Injury of bronchus	0.513	0.487
S92.7 Multiple fractures of foot	0.512	0.488
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.511	0.489
T59.9 Gases, fumes and vapours, unspecified	0.510	0.489
T28 Burn and corrosion of other internal organs	0.510	0.490
T27 Burn and corrosion of respiratory tract	0.510	0.490
T26 Burn and corrosion confined to eye and adnexa	0.510	0.490
T35 Frostbite involving multiple body regions and unspecified frostbite	0.510	0.490
T34 Frostbite with tissue necrosis	0.510	0.490
T33 Superficial frostbite	0.510	0.490
T85.2 Mechanical complication of intraocular lens	0.509	0.491
T02.4 Fractures involving multiple regions of both upper limbs	0.507	0.493
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.505	0.495
T15.9 Foreign body on external eye, unspecified	0.503	0.497
T15.8 Foreign body in other and multiple parts of external eye	0.503	0.497
T15.1 Foreign body in conjunctival sac	0.503	0.497
T15.0 Foreign body in cornea	0.503	0.497
S62.20 Fracture of first metacarpal bone (closed)	0.503	0.497
T32 Corrosions classified according to extent of body surface involved	0.500	0.500
T30 Burn and corrosion, body region unspecified	0.500	0.500
T29 Burns and corrosions of multiple body regions	0.500	0.500
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.500	0.500
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.500	0.500
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.500	0.500
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.500	0.500
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.500	0.500
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.500	0.500
T44.1 Other parasympathomimetics [cholinergics]	0.500	0.500
T44.0 Anticholinesterase agents	0.500	0.500
T01.9 Multiple open wounds, unspecified	0.499	0.501
T01.6 Open wounds involving multiple regions of upper limb(s) with lower limb(s)	0.499	0.501
T01.3 Open wounds involving multiple regions of lower limb(s)	0.499	0.501
T01.1 Open wounds involving thorax with abdomen, lower back and pelvis	0.499	0.501
T01.0 Open wounds involving head with neck	0.499	0.501
T79 Certain early complications of trauma, not elsewhere classified	0.498	0.502
S65.0 Injury of ulnar artery at wrist and hand level	0.496	0.504
T74 Maltreatment syndromes	0.496	0.504
T73 Effects of other deprivation	0.496	0.504
T69 Other effects of reduced temperature	0.496	0.504
T67 Effects of heat and light	0.496	0.504
T71 Asphyxiation	0.496	0.504
T01.2 Open wounds involving multiple regions of upper limb(s)	0.494	0.506
T36.9 Systemic antibiotic, unspecified	0.493	0.506
T36.8 Other systemic antibiotics	0.493	0.506
T36.7 Antifungal antibiotics, systemically used	0.493	0.506
T36.6 Rifamycins	0.493	0.506
T36.5 Aminoglycosides	0.493	0.506
T36.4 Tetracyclines	0.493	0.506
T36.3 Macrolides	0.493	0.506
T36.2 Chloramphenicol group	0.493	0.506
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.493	0.506
T88.5 Other complications of anaesthesia	0.491	0.509
S92.1 Fracture of talus	0.490	0.510
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.490	0.510
T25.2 Burn of second degree of ankle and foot	0.489	0.511
T31 Burns classified according to extent of body surface involved	0.487	0.513
S58 Traumatic amputation of forearm	0.485	0.515
S57 Crushing injury of forearm	0.485	0.515
S55 Injury of blood vessels at forearm level	0.485	0.515
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.485	0.515
S69.8 Other specified injuries of wrist and hand	0.484	0.516
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.483	0.517
S68.8 Traumatic amputation of other parts of wrist and hand	0.483	0.517
S68.4 Traumatic amputation of hand at wrist level	0.483	0.517
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.483	0.517
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.483	0.517
S65.8 Injury of other blood vessels at wrist and hand level	0.483	0.517
S65.7 Injury of multiple blood vessels at wrist and hand level	0.483	0.517
S65.4 Injury of blood vessel(s) of thumb	0.483	0.517
S65.3 Injury of deep palmar arch	0.483	0.517
S65.2 Injury of superficial palmar arch	0.483	0.517
S65.1 Injury of radial artery at wrist and hand level	0.483	0.517
T02.9 Multiple fractures, unspecified	0.483	0.517
T02.8 Fractures involving other combinations of body regions	0.483	0.517
T02.7 Fractures involving thorax with lower back and pelvis with limb(s)	0.483	0.517
T02.6 Fractures involving multiple regions of upper limb(s) with lower limb(s)	0.483	0.517
T02.5 Fractures involving multiple regions of both lower limbs	0.483	0.517
T02.3 Fractures involving multiple regions of one lower limb	0.483	0.517
T02.2 Fractures involving multiple regions of one upper limb	0.483	0.517
T02.1 Fractures involving thorax with lower back and pelvis	0.483	0.517
T02.0 Fractures involving head with neck	0.483	0.517
T75 Effects of other external causes	0.483	0.517
T83.1 Mechanical complication of other urinary devices and implants	0.480	0.519
T38.1 Thyroid hormones and substitutes	0.478	0.521
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.478	0.522
T38.9 Other and unspecified hormone antagonists	0.478	0.522
T38.8 Other and unspecified hormones and their synthetic substitutes	0.478	0.522
T38.7 Androgens and anabolic congeners	0.478	0.522
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.478	0.522
T38.5 Other oestrogens and progestogens	0.478	0.522
T38.4 Oral contraceptives	0.478	0.522
T38.2 Antithyroid drugs	0.478	0.522
T38.0 Glucocorticoids and synthetic analogues	0.478	0.522
S90.9 Superficial injury of ankle and foot, unspecified	0.478	0.522
S54 Injury of nerves at forearm level	0.475	0.525
S51 Open wound of forearm	0.475	0.525
S99.9 Unspecified injury of ankle and foot	0.474	0.526
T82.4 Mechanical complication of vascular dialysis catheter	0.474	0.526
S92.0 Fracture of calcaneus	0.474	0.526
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.474	0.526
T40.8 Lysergide [LSD]	0.474	0.526
T40.7 Cannabis (derivatives)	0.474	0.526
T40.5 Cocaine	0.474	0.526
T40.3 Methadone	0.474	0.526
T40.1 Heroin	0.474	0.526
T40.0 Opium	0.474	0.526
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.474	0.526
S94.9 Injury of unspecified nerve at ankle and foot level	0.473	0.527
S94.8 Injury of other nerves at ankle and foot level	0.473	0.527
S94.7 Injury of multiple nerves at ankle and foot level	0.473	0.527
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.473	0.527
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.473	0.527
S94.1 Injury of medial plantar nerve	0.473	0.527
S94.0 Injury of lateral plantar nerve	0.473	0.527
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.473	0.527
S95.8 Injury of other blood vessels at ankle and foot level	0.473	0.527
S95.7 Injury of multiple blood vessels at ankle and foot level	0.473	0.527
S95.2 Injury of dorsal vein of foot	0.473	0.527
S95.1 Injury of plantar artery of foot	0.473	0.527
S95.0 Injury of dorsal artery of foot	0.473	0.527
S97.8 Crushing injury of other parts of ankle and foot	0.473	0.527
S97.1 Crushing injury of toe(s)	0.473	0.527
S97.0 Crushing injury of ankle	0.473	0.527
S98.4 Traumatic amputation of foot, level unspecified	0.473	0.527
S98.3 Traumatic amputation of other parts of foot	0.473	0.527
S98.2 Traumatic amputation of two or more toes	0.473	0.527
S98.1 Traumatic amputation of one toe	0.473	0.527
S98.0 Traumatic amputation of foot at ankle level	0.473	0.527
S93.0 Dislocation of ankle joint	0.472	0.528
S99.7 Multiple injuries of ankle and foot	0.472	0.528
S80-S89 Injuries to the knee and lower leg	0.472	0.528
S50 Superficial injury of forearm	0.470	0.529
T63.4 Venom of other arthropods	0.470	0.530
T20 Burn and corrosion of head and neck	0.470	0.530
S69.9 Unspecified injury of wrist and hand	0.469	0.531
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.469	0.531
S99.8 Other specified injuries of ankle and foot	0.468	0.532
S92.31 Fracture of metatarsal bone (open)	0.467	0.532
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.467	0.532
T36.0 Penicillins	0.465	0.534
T03.9 Multiple dislocations, sprains and strains, unspecified	0.465	0.534
T03.8 Dislocations, sprains and strains involving other combinations of body regions	0.465	0.534
T03.4 Dislocations, sprains and strains involving multiple regions of upper limb(s) with lower limb(s)	0.465	0.534
T03.3 Dislocations, sprains and strains involving multiple regions of lower limb(s)	0.465	0.534
T03.2 Dislocations, sprains and strains involving multiple regions of upper limb(s)	0.465	0.534
T03.1 Dislocations, sprains and strains involving thorax with lower back and pelvis	0.465	0.534
T03.0 Dislocations, sprains and strains involving head with neck	0.465	0.534
T04.9 Multiple crushing injuries, unspecified	0.465	0.534
T04.8 Crushing injuries involving other combinations of body regions	0.465	0.534
T04.7 Crushing injuries of thorax with abdomen, lower back and pelvis with limb(s)	0.465	0.534
T04.4 Crushing injuries involving multiple regions of upper limb(s) with lower limb(s)	0.465	0.534
T04.3 Crushing injuries involving multiple regions of lower limb(s)	0.465	0.534
T04.2 Crushing injuries involving multiple regions of upper limb(s)	0.465	0.534
T04.1 Crushing injuries involving thorax with abdomen, lower back and pelvis	0.465	0.534
T04.0 Crushing injuries involving head with neck	0.465	0.534
T05.9 Multiple traumatic amputations, unspecified	0.465	0.534
T05.8 Traumatic amputations involving other combinations of body regions	0.465	0.534
T05.6 Traumatic amputation of upper and lower limbs, any combination [any level]	0.465	0.534
T05.5 Traumatic amputation of both legs [any level]	0.465	0.534
T05.4 Traumatic amputation of one foot and other leg [any level, except foot]	0.465	0.534
T05.3 Traumatic amputation of both feet	0.465	0.534
T05.2 Traumatic amputation of both arms [any level]	0.465	0.534
T05.1 Traumatic amputation of one hand and other arm [any level, except hand]	0.465	0.534
T05.0 Traumatic amputation of both hands	0.465	0.534
T06.8 Other specified injuries involving multiple body regions	0.465	0.534
T06.5 Injuries of intrathoracic organs with intra-abdominal and pelvic organs	0.465	0.534
T06.4 Injuries of muscles and tendons involving multiple body regions	0.465	0.534
T06.3 Injuries of blood vessels involving multiple body regions	0.465	0.534
T06.2 Injuries of nerves involving multiple body regions	0.465	0.534
T06.1 Injuries of nerves and spinal cord involving other multiple body regions	0.465	0.534

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations