TreeWAS – Variant ID: rs6059594

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
M50-M54 Other dorsopathies	0.946	0.054
M54 Dorsalgia	0.944	0.056
M54.5 Low back pain	0.938	0.062
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.936	0.064
M51 Other intervertebral disk disorders	0.935	0.065
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.921	0.079
# Top node	0.920	0.080
M54.56 Low back pain (Lumbar region)	0.919	0.081
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.903	0.097
M51.2 Other specified intervertebral disk displacement	0.902	0.098
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.890	0.110
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.885	0.115
M45-M49 Spondylopathies	0.885	0.115
T92 Sequelae of injuries of upper limb	0.881	0.119
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.876	0.124
M45 Ankylosing spondylitis	0.872	0.128
S60-S69 Injuries to the wrist and hand	0.868	0.132
D70-D77 Other diseases of blood and blood-forming organs	0.867	0.133
M45.X9 Ankylosing spondylitis (Site unspecified)	0.857	0.143
T92.1 Sequelae of fracture of arm	0.852	0.148
M54.2 Cervicalgia	0.851	0.149
S40-S49 Injuries to the shoulder and upper arm	0.850	0.150
Chapter VIII Diseases of the ear and mastoid process	0.848	0.152
N63 Unspecified lump in breast	0.846	0.154
Chapter XIV Diseases of the genitourinary system	0.845	0.155
M54.59 Low back pain (Site unspecified)	0.844	0.156
D70 Agranulocytosis	0.842	0.158
S90-S99 Injuries to the ankle and foot	0.840	0.160
M91-M94 Chondropathies	0.839	0.161
N60-N64 Disorders of breast	0.837	0.163
Chapter V Mental and behavioural disorders	0.821	0.179
M40-M43 Deforming dorsopathies	0.815	0.185
M54.57 Low back pain (Lumbosacral region)	0.810	0.190
T51 Toxic effect of alcohol	0.809	0.191
Q60-Q64 Congenital malformations of the urinary system	0.803	0.197
F00-F09 Organic, including symptomatic, mental disorders	0.799	0.201
Chapter VII Diseases of the eye and adnexa	0.799	0.201
H43-H45 Disorders of vitreous body and globe	0.795	0.205
H43 Disorders of vitreous body	0.791	0.209
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.784	0.216
Q20-Q28 Congenital malformations of the circulatory system	0.782	0.218
H43.3 Other vitreous opacities	0.777	0.223
M51.8 Other specified intervertebral disk disorders	0.775	0.225
H60-H62 Diseases of external ear	0.774	0.226
N20-N23 Urolithiasis	0.774	0.226
S66 Injury of muscle and tendon at wrist and hand level	0.767	0.233
D80-D89 Certain disorders involving the immune mechanism	0.764	0.236
M54.29 Cervicalgia-Site unspe	0.762	0.238
F05 Delirium, not induced by alcohol and other psychoactive substances	0.760	0.240
D72 Other disorders of white blood cells	0.758	0.242
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.756	0.244
Chapter XXII Codes for special purposes	0.755	0.245
H80-H83 Diseases of inner ear	0.755	0.245
N20 Calculus of kidney and ureter	0.754	0.246
M51.9 Intervertebral disk disorder, unspecified	0.751	0.249
N20.1 Calculus of ureter	0.749	0.251
D60-D64 Aplastic and other anaemias	0.747	0.253
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.743	0.257
N70-N77 Inflammatory diseases of female pelvic organs	0.741	0.259
T79-T79 Certain early complications of trauma	0.741	0.259
M54.50 Low back pain (Multiple sites in spine)	0.740	0.260
Chapter I Certain infectious and parasitic diseases	0.739	0.261
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.737	0.263
M54.1 Radiculopathy	0.735	0.265
M51.4 Schmorl's nodes	0.734	0.266
T51.0 Ethanol	0.733	0.267
T56 Toxic effect of metals	0.732	0.268
S68 Traumatic amputation of wrist and hand	0.732	0.268
T20-T25 Burns and corrosions of external body surface, specified by site	0.729	0.271
M86-M90 Other osteopathies	0.729	0.271
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.724	0.276
Q61 Cystic kidney disease	0.723	0.277
M54.6 Pain in thoracic spine	0.720	0.279
F05.9 Delirium, unspecified	0.720	0.280
H43.8 Other disorders of vitreous body	0.720	0.280
M94 Other disorders of cartilage	0.719	0.281
T92.9 Sequelae of unspecified injury of upper limb	0.716	0.284
T90 Sequelae of injuries of head	0.714	0.286
T91 Sequelae of injuries of neck and trunk	0.712	0.288
S62 Fracture at wrist and hand level	0.711	0.289
S43.0 Dislocation of shoulder joint	0.710	0.290
D62 Acute posthaemorrhagic anaemia	0.707	0.293
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.706	0.294
H80 Otosclerosis	0.702	0.298
M93 Other osteochondropathies	0.701	0.299
M60-M63 Disorders of muscles	0.689	0.311
M43 Other deforming dorsopathies	0.687	0.313
S90 Superficial injury of ankle and foot	0.685	0.315
S46 Injury of muscle and tendon at shoulder and upper arm level	0.682	0.318
T94 Sequelae of injuries involving multiple and unspecified body regions	0.682	0.318
D72.8 Other specified disorders of white blood cells	0.681	0.319
M54.8 Other dorsalgia	0.677	0.323
M54.0 Panniculitis affecting regions of neck and back	0.677	0.323
S92 Fracture of foot, except ankle	0.677	0.323
H10-H13 Disorders of conjunctiva	0.677	0.323
N10-N16 Renal tubulo-interstitial diseases	0.676	0.324
M48 Other spondylopathies	0.676	0.324
M54.55 Low back pain (Thoracolumbar region)	0.673	0.327
M54.54 Low back pain-Thoracic	0.673	0.327
M54.53 Low back pain-Cervicothoracic	0.673	0.327
M54.52 Low back pain-Cervical	0.673	0.327
M54.51 Low back pain-Occipit-atl-axl	0.673	0.327
Q28 Other congenital malformations of circulatory system	0.672	0.328
M54.22 Cervicalgia (Cervical region)	0.671	0.329
M51.3 Other specified intervertebral disk degeneration	0.670	0.329
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.670	0.329
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.670	0.330
A50-A64 Infections with a predominantly sexual mode of transmission	0.668	0.332
H61 Other disorders of external ear	0.667	0.333
H60 Otitis externa	0.666	0.334
F80-F89 Disorders of psychological development	0.665	0.335
H80.9 Otosclerosis, unspecified	0.664	0.336
T51.9 Alcohol, unspecified	0.664	0.336
Q27 Other congenital malformations of peripheral vascular system	0.661	0.339
D55-D59 Haemolytic anaemias	0.660	0.340
T33-T35 Frostbite	0.660	0.340
T26-T28 Burns and corrosions confined to eye and internal organs	0.660	0.340
T00-T07 Injuries involving multiple body regions	0.660	0.340
F03 Unspecified dementia	0.660	0.340
Chapter XVI Certain conditions originating in the perinatal period	0.659	0.340
T58 Toxic effect of carbon monoxide	0.659	0.341
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.659	0.341
H25-H28 Disorders of lens	0.658	0.342
M41 Scoliosis	0.658	0.342
Q66 Congenital deformities of feet	0.654	0.346
S61 Open wound of wrist and hand	0.654	0.346
H46-H48 Disorders of optic nerve and visual pathways	0.653	0.346
M54.9 Dorsalgia, unspecified	0.653	0.347
T15-T19 Effects of foreign body entering through natural orifice	0.653	0.347
N99-N99 Other disorders of the genitourinary system	0.652	0.347
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.649	0.351
S99 Other and unspecified injuries of ankle and foot	0.649	0.351
S60 Superficial injury of wrist and hand	0.649	0.351
M80-M85 Disorders of bone density and structure	0.649	0.351
B99-B99 Other infectious diseases	0.648	0.352
T95 Sequelae of burns, corrosions and frostbite	0.648	0.352
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.648	0.352
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.648	0.352
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.647	0.353
Q61.2 Polycystic kidney, adult type	0.646	0.354
M54.4 Lumbago with sciatica	0.644	0.356
S50-S59 Injuries to the elbow and forearm	0.644	0.356
S43.1 Dislocation of acromioclavicular joint	0.643	0.357
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.642	0.358
N64 Other disorders of breast	0.639	0.361
S91 Open wound of ankle and foot	0.639	0.361
T59 Toxic effect of other gases, fumes and vapours	0.638	0.361
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.638	0.362
D80 Immunodeficiency with predominantly antibody defects	0.638	0.362
M53 Other dorsopathies, not elsewhere classified	0.638	0.362
Q63 Other congenital malformations of kidney	0.638	0.362
M00-M03 Infectious arthropathies	0.636	0.364
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.635	0.365
Q35-Q37 Cleft lip and cleft palate	0.635	0.365
Q30-Q34 Congenital malformations of the respiratory system	0.635	0.365
M49 Spondylopathies in diseases classified elsewhere	0.635	0.365
T63 Toxic effect of contact with venomous animals	0.635	0.365
T92.2 Sequelae of fracture at wrist and hand level	0.632	0.368
T92.8 Sequelae of other specified injuries of upper limb	0.631	0.368
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.631	0.368
T92.4 Sequelae of injury of nerve of upper limb	0.631	0.368
T93 Sequelae of injuries of lower limb	0.631	0.369
F60-F69 Disorders of adult personality and behaviour	0.631	0.369
T56.8 Other metals	0.629	0.371
Q38-Q45 Other congenital malformations of the digestive system	0.629	0.371
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.629	0.371
S40 Superficial injury of shoulder and upper arm	0.629	0.371
T65 Toxic effect of other and unspecified substances	0.628	0.372
T62 Toxic effect of other noxious substances eaten as food	0.628	0.372
T61 Toxic effect of noxious substances eaten as seafood	0.628	0.372
T60 Toxic effect of pesticides	0.628	0.372
T57 Toxic effect of other inorganic substances	0.628	0.372
T54 Toxic effect of corrosive substances	0.628	0.372
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.628	0.372
T52 Toxic effect of organic solvents	0.628	0.372
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.628	0.372
T55 Toxic effect of soaps and detergents	0.628	0.372
S70-S79 Injuries to the hip and thigh	0.628	0.372
H44 Disorders of globe	0.628	0.372
S69 Other and unspecified injuries of wrist and hand	0.627	0.373
S10-S19 Injuries to the neck	0.627	0.373
F00 Dementia in Alzheimer's disease	0.627	0.373
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.627	0.373
M20-M25 Other joint disorders	0.626	0.374
M65-M68 Disorders of synovium and tendon	0.625	0.375
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.625	0.375
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.625	0.375
M45.X6 Ankylosing spondylitis (Lumbar region)	0.625	0.375
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.625	0.375
M45.X4 Ankylosing spondylitis (Thoracic region)	0.625	0.375
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.625	0.375
M45.X2 Ankylosing spondylitis (Cervical region)	0.625	0.375
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.625	0.375
S61.8 Open wound of other parts of wrist and hand	0.623	0.377
S65 Injury of blood vessels at wrist and hand level	0.622	0.377
T92.0 Sequelae of open wound of upper limb	0.622	0.378
T98 Sequelae of other and unspecified effects of external causes	0.622	0.378
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.621	0.378
D74 Methaemoglobinaemia	0.621	0.378
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.621	0.378
D71 Functional disorders of polymorphonuclear neutrophils	0.621	0.378
H26 Other cataract	0.621	0.379
A30-A49 Other bacterial diseases	0.617	0.383
Q80-Q89 Other congenital malformations	0.616	0.383
M54.19 Radiculopathy (Site unspecified)	0.616	0.384
H43.1 Vitreous haemorrhage	0.614	0.386
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.613	0.386
T79 Certain early complications of trauma, not elsewhere classified	0.612	0.388
Q00-Q07 Congenital malformations of the nervous system	0.612	0.388
T66-T78 Other and unspecified effects of external causes	0.611	0.389
M54.28 Cervicalgia-Sacral/sacrococ	0.610	0.390
M54.27 Cervicalgia-Lumbosacral	0.610	0.390
M54.26 Cervicalgia-Lumbar	0.610	0.390
M54.25 Cervicalgia-Thoracolumbar	0.610	0.390
M54.24 Cervicalgia-Thoracic	0.610	0.390
M54.23 Cervicalgia (Cervicothoracic region)	0.610	0.390
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.610	0.390
M54.20 Cervicalgia-Mult site	0.610	0.390
S48 Traumatic amputation of shoulder and upper arm	0.609	0.390
S45 Injury of blood vessels at shoulder and upper arm level	0.609	0.390
S44 Injury of nerves at shoulder and upper arm level	0.609	0.390
S41 Open wound of shoulder and upper arm	0.609	0.390
S47 Crushing injury of shoulder and upper arm	0.609	0.390
M46 Other inflammatory spondylopathies	0.609	0.391
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.606	0.394
F05.0 Delirium not superimposed on dementia, so described	0.606	0.394
S64 Injury of nerves at wrist and hand level	0.605	0.395
M50 Cervical disk disorders	0.603	0.397
S42 Fracture of shoulder and upper arm	0.603	0.397
H61.2 Impacted cerumen	0.603	0.397
S98 Traumatic amputation of ankle and foot	0.602	0.398
S97 Crushing injury of ankle and foot	0.602	0.398
S96 Injury of muscle and tendon at ankle and foot level	0.602	0.398
S95 Injury of blood vessels at ankle and foot level	0.602	0.398
S94 Injury of nerves at ankle and foot level	0.602	0.398
N13 Obstructive and reflux uropathy	0.602	0.398
M93.9 Osteochondropathy, unspecified	0.602	0.398
M92 Other juvenile osteochondrosis	0.601	0.399
M91 Juvenile osteochondrosis of hip and pelvis	0.601	0.399
T90.2 Sequelae of fracture of skull and facial bones	0.601	0.399
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.600	0.399
S32 Fracture of lumbar spine and pelvis	0.599	0.401
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.599	0.401
Q24 Other congenital malformations of heart	0.598	0.401
H11 Other disorders of conjunctiva	0.597	0.403
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.597	0.403
H60.9 Otitis externa, unspecified	0.597	0.403
N17-N19 Renal failure	0.595	0.405
M94.9 Disorder of cartilage, unspecified	0.595	0.405
Q50-Q56 Congenital malformations of genital organs	0.594	0.406
Q28.2 Arteriovenous malformation of cerebral vessels	0.593	0.407
T23 Burn and corrosion of wrist and hand	0.592	0.408
M25 Other joint disorders, not elsewhere classified	0.592	0.408
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.592	0.408
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.589	0.411
F70-F79 Mental retardation	0.589	0.411
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.587	0.412
N70 Salpingitis and oophoritis	0.586	0.414
M54.17 Radiculopathy (Lumbosacral region)	0.585	0.415
M86 Osteomyelitis	0.585	0.415
M42 Spinal osteochondrosis	0.584	0.416
M40 Kyphosis and lordosis	0.584	0.416
B99 Other and unspecified infectious diseases	0.584	0.416
D89.2 Hypergammaglobulinaemia, unspecified	0.583	0.417
S90.3 Contusion of other and unspecified parts of foot	0.582	0.418
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.581	0.419
Q66.8 Other congenital deformities of feet	0.581	0.419
S66.8 Injury of other muscles and tendons at wrist and hand level	0.581	0.419
H26.8 Other specified cataract	0.580	0.420
T51.8 Other alcohols	0.580	0.420
T51.3 Fusel oil	0.580	0.420
T51.2 2-Propanol	0.580	0.420
T51.1 Methanol	0.580	0.420
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.580	0.420
M94.8 Other specified disorders of cartilage	0.578	0.422
T91.8 Sequelae of other specified injuries of neck and trunk	0.578	0.422
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.578	0.422
S20-S29 Injuries to the thorax	0.577	0.422
Q21 Congenital malformations of cardiac septa	0.577	0.422
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.577	0.423
F01 Vascular dementia	0.577	0.423
M43.1 Spondylolisthesis	0.577	0.423
Q64 Other congenital malformations of urinary system	0.576	0.424
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.576	0.424
M54.3 Sciatica	0.576	0.424
Q60 Renal agenesis and other reduction defects of kidney	0.575	0.425
S46.0 Injury of tendon of the rotator cuff of shoulder	0.575	0.425
F99-F99 Unspecified mental disorder	0.575	0.425
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.575	0.425
Q27.3 Peripheral arteriovenous malformation	0.574	0.426
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.573	0.427
F02 Dementia in other diseases classified elsewhere	0.573	0.427
F09 Unspecified organic or symptomatic mental disorder	0.573	0.427
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.573	0.427
N76 Other inflammation of vagina and vulva	0.573	0.427
D73 Diseases of spleen	0.572	0.428
F40-F48 Neurotic, stress-related and somatoform disorders	0.572	0.428
S49 Other and unspecified injuries of shoulder and upper arm	0.571	0.429
H26.4 After-cataract	0.570	0.430
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.570	0.430
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.567	0.432
H43.9 Disorder of vitreous body, unspecified	0.567	0.433
H43.2 Crystalline deposits in vitreous body	0.567	0.433
H43.0 Vitreous prolapse	0.567	0.433
U80 Agent resistant to penicillin and related antibiotics	0.567	0.433
M25.7 Osteophyte	0.565	0.435
S67 Crushing injury of wrist and hand	0.565	0.435
S62.1 Fracture of other carpal bone(s)	0.563	0.437
S36 Injury of intra-abdominal organs	0.563	0.437
B50-B64 Protozoal diseases	0.562	0.437
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.562	0.438
S43.6 Sprain and strain of sternoclavicular joint	0.562	0.438
S43.5 Sprain and strain of acromioclavicular joint	0.562	0.438
S43.4 Sprain and strain of shoulder joint	0.562	0.438
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.562	0.438
S43.2 Dislocation of sternoclavicular joint	0.562	0.438
D75 Other diseases of blood and blood-forming organs	0.562	0.438
Q65 Congenital deformities of hip	0.562	0.438
Q26 Congenital malformations of great veins	0.561	0.439
Q25 Congenital malformations of great arteries	0.561	0.439
Q22 Congenital malformations of pulmonary and tricuspid valves	0.561	0.439
Q20 Congenital malformations of cardiac chambers and connexions	0.561	0.439
F23 Acute and transient psychotic disorders	0.561	0.439
Chapter XX External causes of morbidity and mortality	0.561	0.439
M54.64 Pain in thoracic spine (Thoracic region)	0.560	0.440
N00-N08 Glomerular diseases	0.559	0.441
N10 Acute tubulo-interstitial nephritis	0.558	0.442
N13.9 Obstructive and reflux uropathy, unspecified	0.557	0.443
Q61.3 Polycystic kidney, unspecified	0.557	0.443
S68.0 Traumatic amputation of thumb (complete)(partial)	0.556	0.444
A15-A19 Tuberculosis	0.555	0.444
H62 Disorders of external ear in diseases classified elsewhere	0.555	0.445
N22 Calculus of urinary tract in diseases classified elsewhere	0.555	0.445
N72 Inflammatory disease of cervix uteri	0.553	0.447
S62.0 Fracture of navicular [scaphoid] bone of hand	0.552	0.448
S62.6 Fracture of other finger	0.551	0.449
N71 Inflammatory disease of uterus, except cervix	0.550	0.450
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.550	0.450
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.550	0.450
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.550	0.450
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.550	0.450
N21 Calculus of lower urinary tract	0.550	0.450
M89 Other disorders of bone	0.550	0.450
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.550	0.450
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.550	0.450
Q76 Congenital malformations of spine and bony thorax	0.549	0.451
M90 Osteopathies in diseases classified elsewhere	0.549	0.451
A63.0 Anogenital (venereal) warts	0.549	0.451
S90.8 Other superficial injuries of ankle and foot	0.548	0.452
D84 Other immunodeficiencies	0.548	0.452
D83 Common variable immunodeficiency	0.548	0.452
D82 Immunodeficiency associated with other major defects	0.548	0.452
D81 Combined immunodeficiencies	0.548	0.452
D80.1 Nonfamilial hypogammaglobulinaemia	0.548	0.452
M41.9 Scoliosis, unspecified	0.545	0.455
F05.8 Other delirium	0.545	0.455
F05.1 Delirium superimposed on dementia	0.545	0.455
M25.74 Osteophyte (Hand)	0.545	0.455
D72.9 Disorder of white blood cells, unspecified	0.543	0.457
D72.0 Genetic anomalies of leukocytes	0.543	0.457
H65-H75 Diseases of middle ear and mastoid	0.543	0.457
Q78 Other osteochondrodysplasias	0.542	0.458
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.542	0.458
Q75 Other congenital malformations of skull and face bones	0.542	0.458
Q74 Other congenital malformations of limb(s)	0.542	0.458
Q73 Reduction defects of unspecified limb	0.542	0.458
Q72 Reduction defects of lower limb	0.542	0.458
Q71 Reduction defects of upper limb	0.542	0.458
Q70 Syndactyly	0.542	0.458
Q69 Polydactyly	0.542	0.458
Q68 Other congenital musculoskeletal deformities	0.542	0.458
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.542	0.458
H82 Vertiginous syndromes in diseases classified elsewhere	0.541	0.459
N64.5 Other signs and symptoms in breast	0.541	0.459
D72.1 Eosinophilia	0.540	0.460
A41 Other septicaemia	0.539	0.461
S92.4 Fracture of great toe	0.539	0.461
T90.5 Sequelae of intracranial injury	0.537	0.463
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.536	0.464
Q61.0 Congenital single renal cyst	0.535	0.464
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.535	0.465
F80 Specific developmental disorders of speech and language	0.535	0.465
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.534	0.466
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.533	0.467
S37 Injury of urinary and pelvic organs	0.533	0.467
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.533	0.467
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.533	0.467
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.533	0.467
S31 Open wound of abdomen, lower back and pelvis	0.533	0.467
M24 Other specific joint derangements	0.533	0.467
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.531	0.469
A60 Anogenital herpesviral [herpes simplex] infections	0.531	0.469
H11.4 Other conjunctival vascular disorders and cysts	0.530	0.470
M54.12 Radiculopathy (Cervical region)	0.530	0.470
B85-B89 Pediculosis, acariasis and other infestations	0.530	0.470
B65-B83 Helminthiases	0.530	0.470
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.530	0.470
A75-A79 Rickettsioses	0.530	0.470
A70-A74 Other diseases caused by chlamydiae	0.530	0.470
A65-A69 Other spirochaetal diseases	0.530	0.470
A20-A28 Certain zoonotic bacterial diseases	0.530	0.470
T91.3 Sequelae of injury of spinal cord	0.529	0.471
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.527	0.473
M54.15 Radiculopathy (Thoracolumbar region)	0.527	0.473
M54.14 Radiculopathy (Thoracic region)	0.527	0.473
M54.13 Radiculopathy (Cervicothoracic region)	0.527	0.473
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.527	0.473
M54.10 Radiculopathy (Multiple sites in spine)	0.527	0.473
N17 Acute renal failure	0.527	0.473
H46 Optic neuritis	0.526	0.474
M50.3 Other cervical disk degeneration	0.526	0.474
M43.0 Spondylolysis	0.525	0.475
T56.9 Metal, unspecified	0.525	0.475
T56.7 Beryllium and its compounds	0.525	0.475
T56.6 Tin and its compounds	0.525	0.475
T56.5 Zinc and its compounds	0.525	0.475
T56.4 Copper and its compounds	0.525	0.475
T56.3 Cadmium and its compounds	0.525	0.475
T56.2 Chromium and its compounds	0.525	0.475
T56.1 Mercury and its compounds	0.525	0.475
T56.0 Lead and its compounds	0.525	0.475
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.525	0.475
S68.8 Traumatic amputation of other parts of wrist and hand	0.525	0.475
S68.4 Traumatic amputation of hand at wrist level	0.525	0.475
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.525	0.475
T94.1 Sequelae of injuries, not specified by body region	0.524	0.476
T25 Burn and corrosion of ankle and foot	0.523	0.477
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.523	0.477
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.523	0.477
T21 Burn and corrosion of trunk	0.523	0.477
T20 Burn and corrosion of head and neck	0.523	0.477
H83 Other diseases of inner ear	0.522	0.478
M48.5 Collapsed vertebra, not elsewhere classified	0.521	0.479
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.521	0.479
S92.1 Fracture of talus	0.519	0.481
Q61.9 Cystic kidney disease, unspecified	0.519	0.481
Q61.8 Other cystic kidney diseases	0.519	0.481
Q61.5 Medullary cystic kidney	0.519	0.481
Q61.4 Renal dysplasia	0.519	0.481
Q61.1 Polycystic kidney, infantile type	0.519	0.481
B20-B24 Human immunodeficiency virus [HIV] disease	0.518	0.482
N20.9 Urinary calculus, unspecified	0.518	0.482
U80.1 Methicillin resistant agent	0.517	0.483
M54.69 Pain in thoracic spine-Site unspe	0.517	0.483
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.517	0.483
M54.67 Pain in thoracic spine-Lumbosacral	0.517	0.483
M54.66 Pain in thoracic spine-Lumbar	0.517	0.483
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.517	0.483
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.517	0.483
M54.62 Pain in thoracic spine-Cervical	0.517	0.483
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.517	0.483
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.517	0.483
S60.9 Superficial injury of wrist and hand, unspecified	0.516	0.484
M54.99 Dorsalgia, unspecified (Site unspecified)	0.516	0.484
S62.8 Fracture of other and unspecified parts of wrist and hand	0.516	0.484
M94.3 Chondrolysis	0.515	0.484
M94.2 Chondromalacia	0.515	0.484
M94.1 Relapsing polychondritis	0.515	0.484
M94.0 Chondrocostal junction syndrome [Tietze]	0.515	0.484
T79.3 Post-traumatic wound infection, not elsewhere classified	0.515	0.485
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.514	0.485
F23.9 Acute and transient psychotic disorder, unspecified	0.514	0.486
M62 Other disorders of muscle	0.513	0.487
T90.8 Sequelae of other specified injuries of head	0.512	0.488
T90.3 Sequelae of injury of cranial nerves	0.512	0.488
T90.1 Sequelae of open wound of head	0.512	0.488
T90.0 Sequelae of superficial injury of head	0.512	0.488
S99.9 Unspecified injury of ankle and foot	0.512	0.488
M85 Other disorders of bone density and structure	0.512	0.488
T91.9 Sequelae of unspecified injury of neck and trunk	0.510	0.489
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.510	0.489
T91.4 Sequelae of injury of intrathoracic organs	0.510	0.489
T91.2 Sequelae of other fracture of thorax and pelvis	0.510	0.489
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.510	0.489
S30 Superficial injury of abdomen, lower back and pelvis	0.510	0.490
S62.7 Multiple fractures of fingers	0.510	0.490
S62.4 Multiple fractures of metacarpal bones	0.510	0.490
T93.0 Sequelae of open wound of lower limb	0.509	0.491
H81 Disorders of vestibular function	0.508	0.491
Q63.1 Lobulated, fused and horseshoe kidney	0.508	0.492
H90-H95 Other disorders of ear	0.508	0.492
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.506	0.494
M25.75 Osteophyte (Pelvic region and thigh)	0.504	0.496
S62.3 Fracture of other metacarpal bone	0.504	0.496
D64 Other anaemias	0.504	0.496
F81 Specific developmental disorders of scholastic skills	0.503	0.496
H80.8 Other otosclerosis	0.503	0.496
H80.2 Cochlear otosclerosis	0.503	0.496
H80.1 Otosclerosis involving oval window, obliterative	0.503	0.496
H80.0 Otosclerosis involving oval window, nonobliterative	0.503	0.496
F00.9 Dementia in Alzheimer's disease, unspecified	0.503	0.497
N13.4 Hydroureter	0.503	0.497
M93.8 Other specified osteochondropathies	0.502	0.498
M93.2 Osteochondritis dissecans	0.502	0.498
M93.1 Kienbock's disease of adults	0.502	0.498
M93.0 Slipped upper femoral epiphysis (nontraumatic)	0.502	0.498
H47 Other disorders of optic [2nd] nerve and visual pathways	0.502	0.498
S62.5 Fracture of thumb	0.501	0.499
T90.9 Sequelae of unspecified injury of head	0.501	0.499
S92.2 Fracture of other tarsal bone(s)	0.500	0.500

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations