TreeWAS – Variant ID: rs6060448

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M17.9 Gonarthrosis, unspecified	0.000	0.000	1.000
M17 Gonarthrosis [arthrosis of knee]	0.000	0.004	0.996
M17.1 Other primary gonarthrosis	0.000	0.012	0.988
M17.5 Other secondary gonarthrosis	0.000	0.104	0.896
M23.3 Other meniscus derangements	0.000	0.133	0.867
M17.3 Other posttraumatic gonarthrosis	0.000	0.140	0.860
M23.2 Derangement of meniscus due to old tear or injury	0.000	0.140	0.860
M23 Internal derangement of knee	0.000	0.141	0.859
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.150	0.850
M17.0 Primary gonarthrosis, bilateral	0.000	0.156	0.844
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.000	0.160	0.840
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.171	0.829
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.000	0.181	0.819
M17.4 Other secondary gonarthrosis, bilateral	0.000	0.241	0.759
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.252	0.748
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.270	0.730
M23.4 Loose body in knee	0.000	0.275	0.725
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.276	0.724
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.281	0.719
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.282	0.718
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.296	0.704
M17.2 Posttraumatic gonarthrosis, bilateral	0.000	0.308	0.692
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.000	0.316	0.684
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.342	0.658
M23.8 Other internal derangements of knee	0.000	0.369	0.631
M23.37 Other meniscus derangements-Capsular lig	0.000	0.378	0.622
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.000	0.383	0.617
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.390	0.610
M23.43 Loose body in knee-Med lig/oth men	0.000	0.391	0.609
M23.49 Loose body in knee-Unspec lig/men	0.000	0.413	0.587
M23.1 Discoid meniscus (congenital)	0.000	0.420	0.579
M23.0 Cystic meniscus	0.000	0.432	0.568
M23.6 Other spontaneous disruption of ligament(s) of knee	0.000	0.435	0.565
M23.5 Chronic instability of knee	0.000	0.443	0.557
M23.9 Internal derangement of knee, unspecified	0.000	0.448	0.552
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.451	0.549
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.454	0.546
M20.1 Hallux valgus (acquired)	0.000	0.455	0.545
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.462	0.538
M23.46 Loose body in knee-O/unsp lat men	0.000	0.471	0.529
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.476	0.524
M23.47 Loose body in knee-Capsular lig	0.000	0.480	0.520
M23.45 Loose body in knee-Pst hrn lat men	0.000	0.480	0.520
M23.44 Loose body in knee-Lat lig/ant men	0.000	0.480	0.520
M23.42 Loose body in knee-Pst lig/hrn men	0.000	0.480	0.520
M23.40 Loose body in knee-Mult sites	0.000	0.480	0.520
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.482	0.518
M23.41 Loose body in knee-Ant lig/hrn men	0.000	0.538	0.462
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.547	0.453
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.548	0.452
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.548	0.452
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.548	0.452
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.000	0.584	0.415
M23.17 Discoid meniscus (congenital)-Capsular lig	0.000	0.584	0.415
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.000	0.584	0.415
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.584	0.415
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.584	0.415
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.584	0.415
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.584	0.415
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.000	0.584	0.415
M23.07 Cystic meniscus-Capsular lig	0.000	0.592	0.407
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.000	0.592	0.407
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.592	0.407
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.592	0.407
M23.00 Cystic meniscus (Multiple sites)	0.000	0.592	0.407
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.000	0.593	0.406
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.595	0.405
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.000	0.595	0.405
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.000	0.595	0.405
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.000	0.595	0.405
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.595	0.405
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.595	0.405
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.595	0.405
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.000	0.595	0.405
M23.57 Chronic instability of knee (Capsular ligament)	0.000	0.600	0.399
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.000	0.600	0.399
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.000	0.600	0.399
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.600	0.399
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.600	0.399
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.600	0.399
M23.50 Chronic instability of knee (Multiple sites)	0.000	0.600	0.399
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.000	0.604	0.396
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.000	0.604	0.396
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.000	0.604	0.396
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.604	0.396
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.604	0.396
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.604	0.396
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.000	0.604	0.396
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.612	0.387
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.614	0.386
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.000	0.618	0.382
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.000	0.620	0.379
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.629	0.371
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.000	0.635	0.365
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.641	0.358
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.646	0.354
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.657	0.343
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.672	0.327
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.682	0.317
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.713	0.287
R59.0 Localised enlarged lymph nodes	0.265	0.735	0.000
M20 Acquired deformities of fingers and toes	0.000	0.771	0.229
M20-M25 Other joint disorders	0.001	0.780	0.219
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.811	0.189
M21 Other acquired deformities of limbs	0.000	0.812	0.188
M21.1 Varus deformity, not elsewhere classified	0.000	0.824	0.176
M20.5 Other deformities of toe(s) (acquired)	0.000	0.831	0.169
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.834	0.166
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.001	0.842	0.157
M34 Systemic sclerosis	0.000	0.850	0.149
M21.2 Flexion deformity	0.000	0.852	0.148
M21.4 Flat foot [pes planus] (acquired)	0.000	0.858	0.142
M21.3 Wrist or foot drop (acquired)	0.000	0.860	0.140
M21.6 Other acquired deformities of ankle and foot	0.000	0.860	0.140
M33 Dermatopolymyositis	0.001	0.862	0.137
M21.9 Acquired deformity of limb, unspecified	0.000	0.865	0.135
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.865	0.135
M32 Systemic lupus erythematosus	0.001	0.865	0.134
M21.8 Other specified acquired deformities of limbs	0.000	0.868	0.132
M21.27 Flexion deformity (Ankle and foot)	0.000	0.873	0.127
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.873	0.126
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.873	0.126
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.873	0.126
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.873	0.126
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.873	0.126
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.873	0.126
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.873	0.126
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.873	0.126
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.875	0.124
B07 Viral warts	0.000	0.876	0.124
M20.3 Other deformity of hallux (acquired)	0.000	0.881	0.119
M30 Polyarteritis nodosa and related conditions	0.001	0.884	0.115
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.001	0.887	0.113
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.001	0.887	0.113
M36.3 Arthropathy in other blood disorders	0.001	0.887	0.113
M36.2 Haemophilic arthropathy	0.001	0.887	0.113
M36.1 Arthropathy in neoplastic disease	0.001	0.887	0.113
M36.0 Dermato(poly)myositis in neoplastic disease	0.001	0.887	0.113
M34.8 Other forms of systemic sclerosis	0.000	0.889	0.111
M34.9 Systemic sclerosis, unspecified	0.000	0.890	0.110
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.891	0.109
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.892	0.107
M34.0 Progressive systemic sclerosis	0.000	0.892	0.107
M21.0 Valgus deformity, not elsewhere classified	0.000	0.893	0.107
M21.29 Flexion deformity (Site unspecified)	0.000	0.894	0.106
M21.28 Flexion deformity (Other)	0.000	0.894	0.106
M21.25 Flexion deformity (Pelvic region and thigh)	0.000	0.894	0.106
M21.23 Flexion deformity (Forearm)	0.000	0.894	0.106
M21.22 Flexion deformity (Upper arm)	0.000	0.894	0.106
M21.21 Flexion deformity (Shoulder region)	0.000	0.894	0.106
M21.20 Flexion deformity (Multiple sites)	0.000	0.894	0.106
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.895	0.105
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.895	0.105
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.898	0.102
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.898	0.102
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.898	0.102
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.898	0.102
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.898	0.102
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.898	0.102
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.898	0.102
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.898	0.102
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.898	0.102
M21.7 Unequal limb length (acquired)	0.000	0.899	0.101
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.899	0.100
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.899	0.100
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.899	0.100
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.899	0.100
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.899	0.100
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.899	0.100
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.899	0.100
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.899	0.100
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.899	0.100
M21.26 Flexion deformity (Lower leg)	0.000	0.899	0.100
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.900	0.100
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.900	0.100
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.900	0.100
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.900	0.100
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.900	0.100
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.900	0.100
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.900	0.100
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.900	0.100
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.000	0.900	0.100
M33.9 Dermatopolymyositis, unspecified	0.001	0.901	0.099
M33.0 Juvenile dermatomyositis	0.001	0.901	0.099
M21.24 Flexion deformity (Hand)	0.000	0.902	0.098
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.000	0.903	0.097
M21.98 Acquired deformity of limb, unspecified-Other	0.000	0.903	0.097
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.000	0.903	0.097
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.000	0.903	0.097
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.000	0.903	0.097
M21.94 Acquired deformity of limb, unspecified (Hand)	0.000	0.903	0.097
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.000	0.903	0.097
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.000	0.903	0.097
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.000	0.903	0.097
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.000	0.903	0.097
M32.9 Systemic lupus erythematosus, unspecified	0.001	0.903	0.096
M32.8 Other forms of systemic lupus erythematosus	0.001	0.903	0.096
M32.0 Drug-induced systemic lupus erythematosus	0.001	0.903	0.096
M48.02 Spinal stenosis (Cervical region)	0.096	0.904	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.905	0.094
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.905	0.094
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.000	0.905	0.094
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.000	0.905	0.094
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.905	0.094
M21.83 Other specified acquired deformities of limbs (Forearm)	0.000	0.905	0.094
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.905	0.094
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.905	0.094
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.905	0.094
M33.1 Other dermatomyositis	0.001	0.907	0.093
M34.1 CR(E)ST syndrome	0.001	0.908	0.091
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.000	0.909	0.091
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.910	0.089
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.910	0.089
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.910	0.089
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.910	0.089
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.000	0.910	0.089
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.910	0.089
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.910	0.089
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.910	0.089
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.910	0.089
M48.0 Spinal stenosis	0.090	0.910	0.000
M33.2 Polymyositis	0.001	0.913	0.087
M31 Other necrotising vasculopathies	0.001	0.916	0.083
M30.8 Other conditions related to polyarteritis nodosa	0.001	0.916	0.083
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.001	0.916	0.083
M30.2 Juvenile polyarteritis	0.001	0.916	0.083
M48 Other spondylopathies	0.082	0.918	0.000
M48.09 Spinal stenosis (Site unspecified)	0.081	0.919	0.000
M22 Disorders of patella	0.001	0.919	0.080
M30.0 Polyarteritis nodosa	0.001	0.920	0.079
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.921	0.079
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.923	0.077
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.923	0.077
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.923	0.077
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.923	0.077
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.923	0.077
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.923	0.077
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.923	0.077
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.923	0.077
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.076	0.924	0.000
R59 Enlarged lymph nodes	0.074	0.926	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.001	0.926	0.073
M21.79 Unequal limb length (acquired) (Site unspecified)	0.001	0.927	0.072
M21.78 Unequal limb length (acquired)-Other	0.001	0.927	0.072
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.001	0.927	0.072
M21.76 Unequal limb length (acquired) (Lower leg)	0.001	0.927	0.072
M21.74 Unequal limb length (acquired) (Hand)	0.001	0.927	0.072
M21.72 Unequal limb length (acquired) (Upper arm)	0.001	0.927	0.072
M21.71 Unequal limb length (acquired)-Shldr region	0.001	0.927	0.072
M21.70 Unequal limb length (acquired) (Multiple sites)	0.001	0.927	0.072
M20.0 Deformity of finger(s)	0.000	0.928	0.071
M13.94 Arthritis, unspecified (Hand)	0.070	0.930	0.000
M45-M49 Spondylopathies	0.070	0.930	0.000
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.001	0.930	0.069
M48.06 Spinal stenosis (Lumbar region)	0.069	0.931	0.000
M45 Ankylosing spondylitis	0.068	0.932	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.932	0.068
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.932	0.067
M48.8 Other specified spondylopathies	0.067	0.933	0.000
M22.2 Patellofemoral disorders	0.000	0.933	0.066
M45.X9 Ankylosing spondylitis (Site unspecified)	0.066	0.934	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.064	0.936	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.064	0.936	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.064	0.936	0.000
M31.3 Wegener's granulomatosis	0.000	0.937	0.063
M48.9 Spondylopathy, unspecified	0.062	0.938	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.938	0.062
M48.5 Collapsed vertebra, not elsewhere classified	0.062	0.938	0.000
M31.9 Necrotising vasculopathy, unspecified	0.000	0.939	0.061
M22.9 Disorder of patella, unspecified	0.001	0.939	0.060
M31.8 Other specified necrotising vasculopathies	0.001	0.940	0.060
M31.7 Microscopic polyangiitis	0.001	0.940	0.060
M31.4 Aortic arch syndrome [Takayasu]	0.001	0.940	0.060
M31.2 Lethal midline granuloma	0.001	0.940	0.060
M21.73 Unequal limb length (acquired) (Forearm)	0.001	0.940	0.059
M22.0 Recurrent dislocation of patella	0.001	0.940	0.059
M31.1 Thrombotic microangiopathy	0.001	0.941	0.059
M48.4 Fatigue fracture of vertebra	0.059	0.941	0.000
M48.3 Traumatic spondylopathy	0.059	0.941	0.000
M48.2 Kissing spine	0.059	0.941	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.059	0.941	0.000
M25.56 Pain in joint (Lower leg)	0.000	0.942	0.058
M22.1 Recurrent subluxation of patella	0.001	0.942	0.058
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.001	0.942	0.057
M48.04 Spinal stenosis (Thoracic region)	0.056	0.944	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.056	0.944	0.000
M49 Spondylopathies in diseases classified elsewhere	0.055	0.944	0.000
M35 Other systemic involvement of connective tissue	0.000	0.944	0.055
M48.87 Other specified spondylopathies (Lumbosacral region)	0.055	0.945	0.000
M25 Other joint disorders, not elsewhere classified	0.000	0.945	0.055
M31.0 Hypersensitivity angiitis	0.001	0.946	0.054
M45.X6 Ankylosing spondylitis (Lumbar region)	0.054	0.946	0.000
M22.3 Other derangements of patella	0.001	0.948	0.052
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.052	0.948	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.001	0.949	0.050
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.000	0.950	0.050
M48.86 Other specified spondylopathies (Lumbar region)	0.050	0.950	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.050	0.950	0.000
M13.9 Arthritis, unspecified	0.050	0.950	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.049	0.951	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.049	0.951	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.049	0.951	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.049	0.951	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.049	0.951	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.049	0.951	0.000
M25.8 Other specified joint disorders	0.000	0.951	0.049
M25.5 Pain in joint	0.000	0.952	0.048
M48.96 Spondylopathy, unspecified (Lumbar region)	0.048	0.952	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.048	0.952	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.048	0.952	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.048	0.952	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.048	0.952	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.048	0.952	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.048	0.952	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.048	0.952	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.048	0.952	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.048	0.952	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.047	0.953	0.000
M24 Other specific joint derangements	0.001	0.953	0.046
R59.9 Enlarged lymph nodes, unspecified	0.047	0.953	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.046	0.954	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.954	0.046
M49.5 Collapsed vertebra in diseases classified elsewhere	0.045	0.955	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.001	0.955	0.045
R59.1 Generalised enlarged lymph nodes	0.045	0.955	0.000
M48.99 Spondylopathy, unspecified (Site unspecified)	0.045	0.955	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.045	0.955	0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.045	0.955	0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.045	0.955	0.000
M48.94 Spondylopathy, unspecified (Thoracic region)	0.045	0.955	0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.045	0.955	0.000
M48.92 Spondylopathy, unspecified (Cervical region)	0.045	0.955	0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.045	0.955	0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.045	0.955	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.045	0.955	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.044	0.955	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.044	0.955	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.044	0.955	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.044	0.955	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.044	0.955	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.044	0.955	0.000
M35.1 Other overlap syndromes	0.000	0.955	0.044
M13 Other arthritis	0.044	0.955	0.000
M25.53 Pain in joint (Forearm)	0.000	0.956	0.044
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.042	0.957	0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.042	0.957	0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.042	0.957	0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.042	0.957	0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.042	0.957	0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.042	0.957	0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.042	0.957	0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.042	0.957	0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.042	0.957	0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.042	0.957	0.000
M48.29 Kissing spine (Site unspecified)	0.042	0.957	0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.042	0.957	0.000
M48.27 Kissing spine (Lumbosacral region)	0.042	0.957	0.000
M48.26 Kissing spine (Lumbar region)	0.042	0.957	0.000
M48.25 Kissing spine (Thoracolumbar region)	0.042	0.957	0.000
M48.24 Kissing spine (Thoracic region)	0.042	0.957	0.000
M48.23 Kissing spine (Cervicothoracic region)	0.042	0.957	0.000
M48.22 Kissing spine (Cervical region)	0.042	0.957	0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.042	0.957	0.000
M48.20 Kissing spine (Multiple sites in spine)	0.042	0.957	0.000
M48.39 Traumatic spondylopathy (Site unspecified)	0.042	0.957	0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.042	0.957	0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.042	0.957	0.000
M48.36 Traumatic spondylopathy (Lumbar region)	0.042	0.957	0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.042	0.957	0.000
M48.34 Traumatic spondylopathy (Thoracic region)	0.042	0.957	0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.042	0.957	0.000
M48.32 Traumatic spondylopathy (Cervical region)	0.042	0.957	0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.042	0.957	0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.042	0.957	0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.042	0.957	0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.042	0.957	0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.042	0.957	0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.042	0.957	0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.042	0.957	0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.042	0.957	0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.042	0.957	0.000
M48.42 Fatigue fracture of vertebra (Cervical region)	0.042	0.957	0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.042	0.957	0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.042	0.957	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.001	0.958	0.042
M24.1 Other articular cartilage disorders	0.000	0.958	0.042
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.038	0.958	0.004
M35.8 Other specified systemic involvement of connective tissue	0.000	0.958	0.042
M05-M14 Inflammatory polyarthropathies	0.041	0.959	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.959	0.041
M13.98 Arthritis, unspecified (Other)	0.040	0.960	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.040	0.960	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.040	0.960	0.000
M49.4 Neuropathic spondylopathy	0.040	0.960	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.040	0.960	0.000
M49.2 Enterobacterial spondylitis	0.040	0.960	0.000
M49.1 Brucella spondylitis	0.040	0.960	0.000
M49.0 Tuberculosis of spine	0.040	0.960	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.960	0.040
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.960	0.040
M35.5 Multifocal fibrosclerosis	0.000	0.960	0.040
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.960	0.040
M13.93 Arthritis, unspecified (Forearm)	0.040	0.960	0.000
M25.2 Flail joint	0.000	0.960	0.040
M25.1 Fistula of joint	0.000	0.960	0.040
M25.3 Other instability of joint	0.000	0.961	0.039
M35.7 Hypermobility syndrome	0.000	0.961	0.039
M13.92 Arthritis, unspecified (Upper arm)	0.039	0.961	0.000
M15-M19 Arthrosis	0.004	0.962	0.035
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.962	0.038
M25.52 Pain in joint (Upper arm)	0.000	0.963	0.037
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.037	0.963	0.000
M25.54 Pain in joint (Hand)	0.000	0.963	0.037
M47 Spondylosis	0.037	0.963	0.000
M86-M90 Other osteopathies	0.036	0.963	0.001
M25.86 Other specified joint disorders (Lower leg)	0.000	0.964	0.036
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.001	0.964	0.036
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)	0.036	0.964	0.000
M14 Arthropathies in other diseases classified elsewhere	0.035	0.964	0.000
M46 Other inflammatory spondylopathies	0.035	0.964	0.000
M77 Other enthesopathies	0.035	0.964	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.965	0.035
M25.82 Other specified joint disorders (Upper arm)	0.000	0.965	0.035
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.965	0.035
M25.0 Haemarthrosis	0.000	0.965	0.035
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.035	0.965	0.000
M77.02 Medial epicondylitis (Upper arm)	0.035	0.965	0.000
M35.2 Behcet's disease	0.000	0.965	0.035
M70-M79 Other soft tissue disorders	0.035	0.965	0.000
M25.88 Other specified joint disorders (Other)	0.000	0.965	0.035
M77.0 Medial epicondylitis	0.035	0.965	0.000
M25.83 Other specified joint disorders (Forearm)	0.000	0.965	0.035
M13.8 Other specified arthritis	0.035	0.965	0.000
M00-M03 Infectious arthropathies	0.032	0.966	0.002
M10 Gout	0.033	0.966	0.000
M90 Osteopathies in diseases classified elsewhere	0.033	0.966	0.000
M91-M94 Chondropathies	0.031	0.967	0.003
M24.6 Ankylosis of joint	0.001	0.967	0.032
M25.34 Other instability of joint (Hand)	0.000	0.967	0.033
M12 Other specific arthropathies	0.033	0.967	0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.033	0.967	0.000
M25.58 Pain in joint (Other)	0.000	0.967	0.033
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)	0.033	0.967	0.000
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)	0.033	0.967	0.000
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)	0.033	0.967	0.000
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)	0.033	0.967	0.000
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)	0.033	0.967	0.000
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)	0.033	0.967	0.000
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)	0.033	0.967	0.000
M25.84 Other specified joint disorders (Hand)	0.000	0.967	0.033
M89 Other disorders of bone	0.032	0.968	0.000
M77.9 Enthesopathy, unspecified	0.032	0.968	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.969	0.031
M14.6 Neuropathic arthropathy	0.031	0.969	0.000
M31.6 Other giant cell arteritis	0.000	0.969	0.031
M60-M63 Disorders of muscles	0.030	0.969	0.002
M22.8 Other disorders of patella	0.001	0.969	0.031
M79.2 Neuralgia and neuritis, unspecified	0.031	0.969	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.001	0.969	0.030
M24.7 Protrusio acetabuli	0.001	0.969	0.030
M89.9 Disorder of bone, unspecified	0.031	0.969	0.000
M25.4 Effusion of joint	0.000	0.969	0.031
M13.1 Monoarthritis, not elsewhere classified	0.031	0.969	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.969	0.030
M25.33 Other instability of joint (Forearm)	0.000	0.969	0.031
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.969	0.030
M90.7 Fracture of bone in neoplastic disease	0.030	0.969	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.970	0.030
M24.18 Other articular cartilage disorders (Other)	0.000	0.970	0.030
M24.14 Other articular cartilage disorders (Hand)	0.000	0.970	0.030
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.970	0.030
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.970	0.030
M77.91 Enthesopathy, unspecified (Shoulder region)	0.030	0.970	0.000
M47.8 Other spondylosis	0.030	0.970	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.030	0.970	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.030	0.970	0.000
M25.36 Other instability of joint (Lower leg)	0.000	0.970	0.030
M09 Juvenile arthritis in diseases classified elsewhere	0.029	0.970	0.000
M08 Juvenile arthritis	0.029	0.970	0.000
M13.0 Polyarthritis, unspecified	0.029	0.970	0.000
M92 Other juvenile osteochondrosis	0.028	0.970	0.001
M24.9 Joint derangement, unspecified	0.001	0.971	0.028
M87 Osteonecrosis	0.029	0.971	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.971	0.029
M89.94 Disorder of bone, unspecified (Hand)	0.029	0.971	0.000
M49.09 Tuberculosis of spine (Site unspecified)	0.029	0.971	0.000
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)	0.029	0.971	0.000
M49.07 Tuberculosis of spine (Lumbosacral region)	0.029	0.971	0.000
M49.06 Tuberculosis of spine (Lumbar region)	0.029	0.971	0.000
M49.05 Tuberculosis of spine (Thoracolumbar region)	0.029	0.971	0.000
M49.04 Tuberculosis of spine (Thoracic region)	0.029	0.971	0.000
M49.03 Tuberculosis of spine (Cervicothoracic region)	0.029	0.971	0.000
M49.02 Tuberculosis of spine (Cervical region)	0.029	0.971	0.000
M49.01 Tuberculosis of spine (Occipito-atlanto-axial region)	0.029	0.971	0.000
M49.00 Tuberculosis of spine (Multiple sites in spine)	0.029	0.971	0.000
M49.19 Brucella spondylitis (Site unspecified)	0.029	0.971	0.000
M49.18 Brucella spondylitis (Sacral and sacrococcygeal region)	0.029	0.971	0.000
M49.17 Brucella spondylitis (Lumbosacral region)	0.029	0.971	0.000
M49.16 Brucella spondylitis (Lumbar region)	0.029	0.971	0.000
M49.15 Brucella spondylitis (Thoracolumbar region)	0.029	0.971	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations