TreeWAS – Variant ID: rs60705247

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	0.998	0.002	0.000
S80-S89 Injuries to the knee and lower leg	0.997	0.003	0.000
J40-J47 Chronic lower respiratory diseases	0.996	0.004	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.996	0.004	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.994	0.006	0.000
M45-M49 Spondylopathies	0.993	0.007	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.993	0.007	0.000
O00-O08 Pregnancy with abortive outcome	0.985	0.015	0.000
M47 Spondylosis	0.981	0.019	0.000
O04 Medical abortion	0.980	0.020	0.000
J44 Other chronic obstructive pulmonary disease	0.977	0.023	0.000
O04.9 Complete or unspecified, without complication	0.973	0.027	0.000
M20-M25 Other joint disorders	0.971	0.029	0.000
J30-J39 Other diseases of upper respiratory tract	0.971	0.029	0.000
J34.3 Hypertrophy of nasal turbinates	0.971	0.029	0.000
J34 Other disorders of nose and nasal sinuses	0.970	0.030	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.968	0.032	0.000
Chapter V Mental and behavioural disorders	0.964	0.036	0.000
J45 Asthma	0.962	0.038	0.000
S82 Fracture of lower leg, including ankle	0.962	0.038	0.000
S80 Superficial injury of lower leg	0.961	0.039	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.957	0.043	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.956	0.044	0.000
S70-S79 Injuries to the hip and thigh	0.948	0.052	0.000
M25 Other joint disorders, not elsewhere classified	0.942	0.058	0.000
J45.9 Asthma, unspecified	0.942	0.058	0.000
S82.8 Fractures of other parts of lower leg	0.942	0.058	0.000
F30-F39 Mood [affective] disorders	0.939	0.061	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.939	0.061	0.000
M24 Other specific joint derangements	0.939	0.061	0.000
T93 Sequelae of injuries of lower limb	0.927	0.073	0.000
M25.5 Pain in joint	0.925	0.075	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.923	0.077	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.919	0.081	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.919	0.081	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.911	0.089	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.911	0.089	0.000
M47.9 Spondylosis, unspecified	0.911	0.089	0.000
S72 Fracture of femur	0.906	0.094	0.000
M65-M68 Disorders of synovium and tendon	0.904	0.096	0.000
Chapter VIII Diseases of the ear and mastoid process	0.903	0.097	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.897	0.103	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.897	0.103	0.000
O85-O92 Complications predominantly related to the puerperium	0.897	0.103	0.000
M48 Other spondylopathies	0.896	0.104	0.000
M47.2 Other spondylosis with radiculopathy	0.895	0.105	0.000
J36 Peritonsillar abscess	0.890	0.110	0.000
S80.8 Other superficial injuries of lower leg	0.886	0.114	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.884	0.116	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.879	0.121	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.878	0.122	0.000
S82.3 Fracture of lower end of tibia	0.873	0.127	0.000
M35 Other systemic involvement of connective tissue	0.870	0.130	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.866	0.134	0.000
J46 Status asthmaticus	0.866	0.134	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.865	0.135	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.862	0.138	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.861	0.139	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.860	0.140	0.000
S10-S19 Injuries to the neck	0.851	0.149	0.000
F33 Recurrent depressive disorder	0.848	0.152	0.000
O60-O75 Complications of labour and delivery	0.847	0.153	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.843	0.157	0.000
T93.2 Sequelae of other fractures of lower limb	0.841	0.159	0.000
M47.8 Other spondylosis	0.840	0.160	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.840	0.160	0.000
J34.2 Deviated nasal septum	0.839	0.161	0.000
S80.9 Superficial injury of lower leg, unspecified	0.839	0.161	0.000
H80-H83 Diseases of inner ear	0.838	0.162	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.837	0.163	0.000
J42 Unspecified chronic bronchitis	0.837	0.163	0.000
F31 Bipolar affective disorder	0.833	0.167	0.000
M50-M54 Other dorsopathies	0.831	0.169	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.829	0.171	0.000
M80-M85 Disorders of bone density and structure	0.828	0.172	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.827	0.173	0.000
M48.0 Spinal stenosis	0.823	0.177	0.000
S90-S99 Injuries to the ankle and foot	0.817	0.183	0.000
O04.4 Incomplete, without complication	0.813	0.187	0.000
F32 Depressive episode	0.812	0.188	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.807	0.193	0.000
T87 Complications peculiar to reattachment and amputation	0.807	0.193	0.000
T23 Burn and corrosion of wrist and hand	0.806	0.194	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.805	0.195	0.000
Chapter VI Diseases of the nervous system	0.805	0.195	0.000
S82.30 Fracture of lower end of tibia (closed)	0.804	0.196	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.802	0.198	0.000
J84 Other interstitial pulmonary diseases	0.800	0.200	0.000
M25.53 Pain in joint (Forearm)	0.800	0.200	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.800	0.200	0.000
O80-O84 Delivery	0.800	0.200	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.799	0.200	0.000
T93.1 Sequelae of fracture of femur	0.798	0.201	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.798	0.202	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.796	0.204	0.000
S89 Other and unspecified injuries of lower leg	0.795	0.205	0.000
Chapter XX External causes of morbidity and mortality	0.794	0.206	0.000
S72.3 Fracture of shaft of femur	0.794	0.206	0.000
M86-M90 Other osteopathies	0.793	0.207	0.000
O86 Other puerperal infections	0.792	0.208	0.000
M25.59 Pain in joint (Site unspecified)	0.791	0.209	0.000
M91-M94 Chondropathies	0.790	0.210	0.000
M05-M14 Inflammatory polyarthropathies	0.790	0.210	0.000
T00-T07 Injuries involving multiple body regions	0.789	0.211	0.000
S80.0 Contusion of knee	0.788	0.212	0.000
H90-H95 Other disorders of ear	0.788	0.212	0.000
S81 Open wound of lower leg	0.787	0.213	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.787	0.213	0.000
M67 Other disorders of synovium and tendon	0.786	0.214	0.000
J90-J94 Other diseases of pleura	0.785	0.215	0.000
M25.9 Joint disorder, unspecified	0.784	0.216	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.783	0.217	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.782	0.218	0.000
M66 Spontaneous rupture of synovium and tendon	0.782	0.218	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.781	0.219	0.000
M24.5 Contracture of joint	0.781	0.219	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.779	0.221	0.000
S40-S49 Injuries to the shoulder and upper arm	0.778	0.222	0.000
H81 Disorders of vestibular function	0.776	0.224	0.000
T90 Sequelae of injuries of head	0.773	0.227	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.770	0.230	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.770	0.230	0.000
M25.58 Pain in joint (Other)	0.767	0.233	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.765	0.235	0.000
M00-M03 Infectious arthropathies	0.763	0.237	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.763	0.237	0.000
M47.1 Other spondylosis with myelopathy	0.763	0.237	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.762	0.238	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.761	0.239	0.000
M30 Polyarteritis nodosa and related conditions	0.760	0.240	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.760	0.240	0.000
T79-T79 Certain early complications of trauma	0.760	0.240	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.758	0.242	0.000
S72.1 Pertrochanteric fracture	0.757	0.243	0.000
J92 Pleural plaque	0.757	0.243	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.757	0.243	0.000
T21 Burn and corrosion of trunk	0.756	0.244	0.000
M25.50 Pain in joint (Multiple sites)	0.755	0.245	0.000
M35.3 Polymyalgia rheumatica	0.755	0.245	0.000
M25.52 Pain in joint (Upper arm)	0.754	0.246	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.754	0.246	0.000
M60-M63 Disorders of muscles	0.754	0.246	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.752	0.248	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.751	0.249	0.000
S72.0 Fracture of neck of femur	0.749	0.251	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.749	0.251	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.748	0.252	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.748	0.252	0.000
M21 Other acquired deformities of limbs	0.747	0.253	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.746	0.254	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.744	0.256	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.744	0.256	0.000
M47.86 Other spondylosis (Lumbar region)	0.743	0.257	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.742	0.258	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.741	0.259	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.740	0.260	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.740	0.260	0.000
M35.0 Sicca syndrome [Sjogren]	0.740	0.260	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.737	0.263	0.000
F80-F89 Disorders of psychological development	0.737	0.263	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.737	0.263	0.000
M49 Spondylopathies in diseases classified elsewhere	0.737	0.263	0.000
S82.2 Fracture of shaft of tibia	0.736	0.264	0.000
M24.1 Other articular cartilage disorders	0.734	0.266	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.733	0.267	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.733	0.267	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.732	0.268	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.731	0.268	0.000
M46 Other inflammatory spondylopathies	0.730	0.270	0.000
J92.0 Pleural plaque with presence of asbestos	0.730	0.270	0.000
H91 Other hearing loss	0.730	0.270	0.000
S82.81 Fractures of other parts of lower leg (open)	0.729	0.270	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.728	0.272	0.000
F43 Reaction to severe stress, and adjustment disorders	0.728	0.272	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.726	0.273	0.000
T23.2 Burn of second degree of wrist and hand	0.726	0.274	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.725	0.275	0.001
O02 Other abnormal products of conception	0.725	0.275	0.000
M24.0 Loose body in joint	0.724	0.276	0.000
M24.2 Disorder of ligament	0.724	0.276	0.000
H80 Otosclerosis	0.724	0.276	0.000
O66 Other obstructed labour	0.723	0.276	0.000
M06 Other rheumatoid arthritis	0.723	0.277	0.000
T36 Poisoning by systemic antibiotics	0.723	0.277	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.722	0.278	0.000
T66-T78 Other and unspecified effects of external causes	0.722	0.278	0.000
S60-S69 Injuries to the wrist and hand	0.720	0.280	0.000
T98 Sequelae of other and unspecified effects of external causes	0.719	0.281	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.718	0.281	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.718	0.282	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.717	0.282	0.000
O86.4 Pyrexia of unknown origin following delivery	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
S72.8 Fractures of other parts of femur	0.715	0.285	0.000
S88 Traumatic amputation of lower leg	0.715	0.285	0.000
S87 Crushing injury of lower leg	0.715	0.285	0.000
S86 Injury of muscle and tendon at lower leg level	0.715	0.285	0.000
S85 Injury of blood vessels at lower leg level	0.715	0.285	0.000
S84 Injury of nerves at lower leg level	0.715	0.285	0.000
M25.0 Haemarthrosis	0.714	0.286	0.000
F31.9 Bipolar affective disorder, unspecified	0.714	0.286	0.000
J41 Simple and mucopurulent chronic bronchitis	0.714	0.286	0.000
O03 Spontaneous abortion	0.714	0.286	0.000
S72.30 Fracture of shaft of femur (closed)	0.714	0.286	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.713	0.287	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.710	0.290	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.709	0.291	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.707	0.293	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.706	0.294	0.000
O07 Failed attempted abortion	0.706	0.294	0.000
O06 Unspecified abortion	0.706	0.294	0.000
O05 Other abortion	0.706	0.294	0.000
O01 Hydatidiform mole	0.706	0.294	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.704	0.296	0.000
M53 Other dorsopathies, not elsewhere classified	0.704	0.296	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.702	0.297	0.000
O04.7 Complete or unspecified, complicated by embolism	0.702	0.297	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.702	0.297	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.702	0.297	0.000
O04.3 Incomplete, with other and unspecified complications	0.702	0.297	0.000
O04.2 Incomplete, complicated by embolism	0.702	0.297	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.702	0.297	0.000
M15-M19 Arthrosis	0.702	0.298	0.000
F99-F99 Unspecified mental disorder	0.700	0.300	0.000
F32.1 Moderate depressive episode	0.698	0.302	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.696	0.303	0.000
M33 Dermatopolymyositis	0.696	0.303	0.000
M32 Systemic lupus erythematosus	0.696	0.303	0.000
S81.9 Open wound of lower leg, part unspecified	0.696	0.304	0.000
J60-J70 Lung diseases due to external agents	0.696	0.304	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.696	0.304	0.000
O87 Venous complications in the puerperium	0.695	0.305	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.695	0.305	0.000
M25.8 Other specified joint disorders	0.695	0.305	0.000
M67.8 Other specified disorders of synovium and tendon	0.695	0.305	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.694	0.306	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.694	0.306	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.694	0.306	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.694	0.306	0.000
S91 Open wound of ankle and foot	0.693	0.307	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.693	0.307	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.692	0.308	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.692	0.308	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.691	0.308	0.000
F70-F79 Mental retardation	0.691	0.308	0.000
S32 Fracture of lumbar spine and pelvis	0.690	0.309	0.000
J45.8 Mixed asthma	0.690	0.310	0.000
J45.1 Nonallergic asthma	0.690	0.310	0.000
S82.9 Fracture of lower leg, part unspecified	0.690	0.310	0.000
S82.7 Multiple fractures of lower leg	0.690	0.310	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.689	0.311	0.000
S80.7 Multiple superficial injuries of lower leg	0.689	0.311	0.000
H91.9 Hearing loss, unspecified	0.689	0.311	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.687	0.313	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.687	0.313	0.000
M82 Osteoporosis in diseases classified elsewhere	0.687	0.313	0.000
T95 Sequelae of burns, corrosions and frostbite	0.686	0.314	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.686	0.314	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.686	0.314	0.000
T83.2 Mechanical complication of graft of urinary organ	0.686	0.314	0.000
O80 Single spontaneous delivery	0.686	0.314	0.000
H60-H62 Diseases of external ear	0.684	0.316	0.000
O90 Complications of the puerperium, not elsewhere classified	0.684	0.316	0.000
Chapter XXII Codes for special purposes	0.684	0.316	0.000
H81.0 Meniere's disease	0.683	0.317	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.683	0.317	0.000
M51 Other intervertebral disk disorders	0.682	0.318	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.682	0.318	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.681	0.319	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.681	0.319	0.000
M21.3 Wrist or foot drop (acquired)	0.680	0.320	0.000
H90 Conductive and sensorineural hearing loss	0.680	0.320	0.000
S78 Traumatic amputation of hip and thigh	0.680	0.320	0.000
S77 Crushing injury of hip and thigh	0.680	0.320	0.000
S75 Injury of blood vessels at hip and thigh level	0.680	0.320	0.000
S74 Injury of nerves at hip and thigh level	0.680	0.320	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.679	0.321	0.000
J39 Other diseases of upper respiratory tract	0.677	0.323	0.000
M25.2 Flail joint	0.675	0.324	0.000
M25.1 Fistula of joint	0.675	0.324	0.000
S82.86 Maisonneuve's fracture	0.675	0.325	0.000
T20 Burn and corrosion of head and neck	0.674	0.326	0.000
F38 Other mood [affective] disorders	0.673	0.326	0.000
F34 Persistent mood [affective] disorders	0.673	0.326	0.000
F39 Unspecified mood [affective] disorder	0.673	0.326	0.000
M24.9 Joint derangement, unspecified	0.673	0.327	0.000
M24.7 Protrusio acetabuli	0.673	0.327	0.000
M24.6 Ankylosis of joint	0.673	0.327	0.000
M54 Dorsalgia	0.673	0.327	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.672	0.328	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.672	0.328	0.000
M34 Systemic sclerosis	0.672	0.328	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.672	0.328	0.000
S70 Superficial injury of hip and thigh	0.671	0.329	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.671	0.329	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.670	0.330	0.000
S92 Fracture of foot, except ankle	0.668	0.332	0.000
T93.0 Sequelae of open wound of lower limb	0.667	0.332	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.667	0.332	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.667	0.333	0.000
M94 Other disorders of cartilage	0.666	0.334	0.000
T87.3 Neuroma of amputation stump	0.666	0.334	0.000
J40 Bronchitis, not specified as acute or chronic	0.666	0.334	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.666	0.334	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.665	0.335	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.665	0.335	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.665	0.335	0.000
F30 Manic episode	0.665	0.335	0.000
S20-S29 Injuries to the thorax	0.664	0.336	0.000
T39.1 4-Aminophenol derivatives	0.661	0.339	0.000
S83.7 Injury to multiple structures of knee	0.660	0.340	0.000
S72.2 Subtrochanteric fracture	0.659	0.340	0.000
J34.0 Abscess, furuncle and carbuncle of nose	0.659	0.341	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.659	0.341	0.000
O97 Death from sequelae of direct obstetric causes	0.659	0.341	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.659	0.341	0.000
O95 Obstetric death of unspecified cause	0.659	0.341	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.659	0.341	0.000
M40-M43 Deforming dorsopathies	0.659	0.341	0.000
T25 Burn and corrosion of ankle and foot	0.659	0.341	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.659	0.341	0.000
M47.89 Other spondylosis (Site unspecified)	0.658	0.342	0.000
O62 Abnormalities of forces of labour	0.658	0.342	0.000
M06.9 Rheumatoid arthritis, unspecified	0.657	0.343	0.000
M66.0 Rupture of popliteal cyst	0.657	0.343	0.000
J47 Bronchiectasis	0.656	0.344	0.000
F33.9 Recurrent depressive disorder, unspecified	0.655	0.344	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.655	0.345	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.655	0.345	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.653	0.347	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.653	0.347	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.653	0.347	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.653	0.347	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.653	0.347	0.000
W50-W64 Exposure to animate mechanical forces	0.652	0.348	0.000
X50-X57 Overexertion, travel and privation	0.652	0.348	0.000
T86 Failure and rejection of transplanted organs and tissues	0.652	0.348	0.000
F40 Phobic anxiety disorders	0.652	0.348	0.000
S19 Other and unspecified injuries of neck	0.652	0.348	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.651	0.349	0.000
S82.0 Fracture of patella	0.650	0.350	0.000
S72.10 Pertrochanteric fracture (closed)	0.650	0.350	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.650	0.350	0.000
S72.9 Fracture of femur, part unspecified	0.650	0.350	0.000
S72.7 Multiple fractures of femur	0.650	0.350	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.649	0.350	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.648	0.352	0.000
M14 Arthropathies in other diseases classified elsewhere	0.648	0.352	0.000
M51.2 Other specified intervertebral disk displacement	0.647	0.353	0.000
S82.31 Fracture of lower end of tibia (open)	0.647	0.353	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.644	0.356	0.000
M48.09 Spinal stenosis (Site unspecified)	0.644	0.356	0.000
S13.4 Sprain and strain of cervical spine	0.644	0.356	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.644	0.356	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.643	0.357	0.000
O91 Infections of breast associated with childbirth	0.643	0.357	0.000
O89 Complications of anaesthesia during the puerperium	0.643	0.357	0.000
O88 Obstetric embolism	0.643	0.357	0.000
O85 Puerperal sepsis	0.643	0.357	0.000
H80.9 Otosclerosis, unspecified	0.643	0.357	0.000
M48.9 Spondylopathy, unspecified	0.642	0.357	0.000
M48.8 Other specified spondylopathies	0.642	0.357	0.000
M48.4 Fatigue fracture of vertebra	0.642	0.357	0.000
M48.3 Traumatic spondylopathy	0.642	0.357	0.000
M48.2 Kissing spine	0.642	0.357	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.642	0.357	0.000
J37 Chronic laryngitis and laryngotracheitis	0.642	0.357	0.000
S50-S59 Injuries to the elbow and forearm	0.642	0.358	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.642	0.358	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.642	0.358	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.642	0.358	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.642	0.358	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.642	0.358	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.642	0.358	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.642	0.358	0.000
W20-W49 Exposure to inanimate mechanical forces	0.642	0.358	0.000
M45 Ankylosing spondylitis	0.642	0.358	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.641	0.358	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.641	0.359	0.000
V80-V89 Other land transport accidents	0.640	0.360	0.000
T13 Other injuries of lower limb, level unspecified	0.640	0.360	0.000
V01-V09 Pedestrian injured in transport accident	0.639	0.361	0.000
F60-F69 Disorders of adult personality and behaviour	0.639	0.361	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.639	0.361	0.000
J31.2 Chronic pharyngitis	0.638	0.362	0.000
T00 Superficial injuries involving multiple body regions	0.638	0.362	0.000
S89.9 Unspecified injury of lower leg	0.638	0.362	0.000
J45.0 Predominantly allergic asthma	0.636	0.363	0.000
S72.00 Fracture of neck of femur (closed)	0.636	0.364	0.000
X20-X29 Contact with venomous animals and plants	0.636	0.364	0.000
S72.4 Fracture of lower end of femur	0.636	0.364	0.000
M19 Other arthrosis	0.635	0.365	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.634	0.366	0.000
M25.94 Joint disorder, unspecified (Hand)	0.634	0.366	0.000
F11 Mental and behavioural disorders due to use of opioids	0.634	0.366	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.633	0.367	0.000
S71 Open wound of hip and thigh	0.633	0.367	0.000
S82.5 Fracture of medial malleolus	0.632	0.368	0.000
H81.3 Other peripheral vertigo	0.632	0.368	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.632	0.368	0.000
T39.0 Salicylates	0.630	0.370	0.000
M24.51 Contracture of joint (Shoulder region)	0.630	0.370	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.629	0.371	0.000
H81.1 Benign paroxysmal vertigo	0.629	0.371	0.000
M25.54 Pain in joint (Hand)	0.628	0.372	0.000
Y00-Y09 Assault	0.627	0.373	0.000
F43.1 Posttraumatic stress disorder	0.627	0.373	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.627	0.373	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.626	0.374	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.626	0.374	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.626	0.374	0.000
J34.1 Cyst and mucocele of nose and nasal sinus	0.625	0.375	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.624	0.376	0.000
M35.8 Other specified systemic involvement of connective tissue	0.624	0.376	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.624	0.376	0.000
M35.5 Multifocal fibrosclerosis	0.624	0.376	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.624	0.376	0.000
M35.2 Behcet's disease	0.624	0.376	0.000
M35.1 Other overlap syndromes	0.624	0.376	0.000
S31 Open wound of abdomen, lower back and pelvis	0.624	0.376	0.000
H90.5 Sensorineural hearing loss, unspecified	0.623	0.377	0.000
M80 Osteoporosis with pathological fracture	0.623	0.377	0.000
T91 Sequelae of injuries of neck and trunk	0.623	0.377	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.622	0.378	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.622	0.378	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.622	0.378	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.621	0.379	0.000
T80.6 Other serum reactions	0.621	0.379	0.000
T80.5 Anaphylactic shock due to serum	0.621	0.379	0.000
T80.4 Rh incompatibility reaction	0.621	0.379	0.000
T80.3 ABO incompatibility reaction	0.621	0.379	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.621	0.379	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.621	0.379	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.620	0.379	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.619	0.380	0.000
M05 Seropositive rheumatoid arthritis	0.619	0.381	0.000
O61 Failed induction of labour	0.618	0.382	0.000
J33 Nasal polyp	0.618	0.382	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.618	0.382	0.000
M87 Osteonecrosis	0.618	0.382	0.000
S37 Injury of urinary and pelvic organs	0.617	0.383	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.617	0.383	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.617	0.383	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.617	0.383	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.617	0.383	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.617	0.383	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.617	0.383	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.617	0.383	0.000
T39.4 Antirheumatics, not elsewhere classified	0.617	0.383	0.000
T39.2 Pyrazolone derivatives	0.617	0.383	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.617	0.383	0.000
M89 Other disorders of bone	0.616	0.384	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.616	0.384	0.000
M24.54 Contracture of joint (Hand)	0.615	0.385	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.615	0.385	0.000
S82.6 Fracture of lateral malleolus	0.613	0.387	0.000
S12 Fracture of neck	0.613	0.387	0.000
T90.1 Sequelae of open wound of head	0.613	0.387	0.000
T40.4 Other synthetic narcotics	0.613	0.387	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.612	0.388	0.000
O71 Other obstetric trauma	0.612	0.388	0.000
J84.8 Other specified interstitial pulmonary diseases	0.611	0.389	0.000
S17 Crushing injury of neck	0.610	0.390	0.000
S15 Injury of blood vessels at neck level	0.610	0.390	0.000
S11 Open wound of neck	0.610	0.390	0.000
S18 Traumatic amputation at neck level	0.610	0.390	0.000
S16 Injury of muscle and tendon at neck level	0.610	0.390	0.000
O80.0 Spontaneous vertex delivery	0.610	0.390	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.610	0.390	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.609	0.391	0.000
M81 Osteoporosis without pathological fracture	0.609	0.391	0.000
F33.8 Other recurrent depressive disorders	0.608	0.392	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.608	0.392	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.608	0.392	0.000
T21.2 Burn of second degree of trunk	0.608	0.392	0.000
J80 Adult respiratory distress syndrome	0.608	0.392	0.000
O74 Complications of anaesthesia during labour and delivery	0.608	0.392	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.608	0.392	0.000
O60 Preterm delivery	0.608	0.392	0.000
S42 Fracture of shoulder and upper arm	0.607	0.393	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.606	0.394	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.605	0.394	0.000
T58 Toxic effect of carbon monoxide	0.605	0.395	0.000
M84 Disorders of continuity of bone	0.603	0.396	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.602	0.397	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.602	0.397	0.000
M47.84 Other spondylosis (Thoracic region)	0.602	0.397	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.602	0.397	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.602	0.397	0.000
T50.8 Diagnostic agents	0.602	0.397	0.000
T50.7 Analeptics and opioid receptor antagonists	0.602	0.397	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.602	0.397	0.000
T50.5 Appetite depressants	0.602	0.397	0.000
T50.4 Drugs affecting uric acid metabolism	0.602	0.397	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.602	0.397	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations