TreeWAS – Variant ID: rs6097169

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.496	0.504	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.494	0.506	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.493	0.507	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.486	0.514	0.000
T90 Sequelae of injuries of head	0.482	0.518	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.471	0.529	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.468	0.532	0.000
T43.2 Other and unspecified antidepressants	0.466	0.534	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.462	0.538	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.456	0.544	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.451	0.549	0.000
T92 Sequelae of injuries of upper limb	0.448	0.552	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.446	0.554	0.000
S60-S69 Injuries to the wrist and hand	0.441	0.559	0.000
S50-S59 Injuries to the elbow and forearm	0.440	0.560	0.000
S40-S49 Injuries to the shoulder and upper arm	0.434	0.566	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.432	0.568	0.000
T93 Sequelae of injuries of lower limb	0.424	0.576	0.000
S62 Fracture at wrist and hand level	0.420	0.580	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.420	0.580	0.000
T90.4 Sequelae of injury of eye and orbit	0.418	0.582	0.000
S20-S29 Injuries to the thorax	0.411	0.589	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.411	0.589	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.410	0.590	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.406	0.594	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.405	0.594	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.405	0.595	0.000
S62.6 Fracture of other finger	0.405	0.595	0.000
T86 Failure and rejection of transplanted organs and tissues	0.399	0.601	0.000
S42 Fracture of shoulder and upper arm	0.396	0.604	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.392	0.608	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.392	0.608	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.391	0.609	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.389	0.610	0.000
S40 Superficial injury of shoulder and upper arm	0.388	0.612	0.000
T43.6 Psychostimulants with abuse potential	0.388	0.612	0.000
S62.61 Fracture of other finger (open)	0.388	0.612	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.387	0.613	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.386	0.614	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.385	0.615	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.384	0.616	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.384	0.616	0.000
S56 Injury of muscle and tendon at forearm level	0.381	0.619	0.000
T82.1 Mechanical complication of cardiac electronic device	0.380	0.620	0.000
T40.4 Other synthetic narcotics	0.379	0.621	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.376	0.624	0.000
T93.1 Sequelae of fracture of femur	0.376	0.624	0.000
S69 Other and unspecified injuries of wrist and hand	0.375	0.625	0.000
T98 Sequelae of other and unspecified effects of external causes	0.372	0.628	0.000
T40.2 Other opioids	0.372	0.628	0.000
T00-T07 Injuries involving multiple body regions	0.370	0.630	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.368	0.632	0.000
T95 Sequelae of burns, corrosions and frostbite	0.367	0.633	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.365	0.634	0.000
T90.1 Sequelae of open wound of head	0.364	0.636	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.363	0.637	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.363	0.637	0.000
T90.5 Sequelae of intracranial injury	0.361	0.639	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.361	0.639	0.000
T40.6 Other and unspecified narcotics	0.360	0.640	0.000
S42.2 Fracture of upper end of humerus	0.359	0.641	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.359	0.641	0.000
T85.2 Mechanical complication of intraocular lens	0.359	0.641	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.358	0.642	0.000
T87 Complications peculiar to reattachment and amputation	0.356	0.644	0.000
T90.9 Sequelae of unspecified injury of head	0.356	0.644	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.356	0.644	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.356	0.644	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.355	0.644	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.355	0.644	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.355	0.644	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.355	0.645	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.354	0.646	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.354	0.646	0.000
T33-T35 Frostbite	0.354	0.646	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.354	0.646	0.000
S52 Fracture of forearm	0.351	0.649	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.351	0.649	0.000
T43.9 Psychotropic drug, unspecified	0.349	0.651	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.349	0.651	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.349	0.651	0.000
T36 Poisoning by systemic antibiotics	0.348	0.652	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.347	0.652	0.000
T90.8 Sequelae of other specified injuries of head	0.346	0.654	0.000
T90.3 Sequelae of injury of cranial nerves	0.346	0.654	0.000
T90.0 Sequelae of superficial injury of head	0.346	0.654	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.346	0.654	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.344	0.656	0.000
T20 Burn and corrosion of head and neck	0.343	0.657	0.000
S54 Injury of nerves at forearm level	0.338	0.662	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.337	0.663	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.335	0.665	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.335	0.665	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.334	0.666	0.000
S59 Other and unspecified injuries of forearm	0.334	0.666	0.000
S52.1 Fracture of upper end of radius	0.333	0.667	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.332	0.667	0.000
S42.20 Fracture of upper end of humerus (closed)	0.332	0.668	0.000
S27 Injury of other and unspecified intrathoracic organs	0.332	0.668	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.329	0.671	0.000
S50 Superficial injury of forearm	0.328	0.672	0.000
S69.9 Unspecified injury of wrist and hand	0.328	0.672	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.328	0.672	0.000
S65 Injury of blood vessels at wrist and hand level	0.327	0.673	0.000
S32 Fracture of lumbar spine and pelvis	0.327	0.673	0.000
S62.60 Fracture of other finger (closed)	0.326	0.674	0.000
T11 Other injuries of upper limb, level unspecified	0.324	0.676	0.000
S42.1 Fracture of scapula	0.324	0.676	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.323	0.676	0.000
T40.8 Lysergide [LSD]	0.323	0.676	0.000
T40.7 Cannabis (derivatives)	0.323	0.676	0.000
T40.5 Cocaine	0.323	0.676	0.000
T40.3 Methadone	0.323	0.676	0.000
T40.1 Heroin	0.323	0.676	0.000
T40.0 Opium	0.323	0.676	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.321	0.679	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.321	0.679	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.321	0.679	0.000
T45.0 Antiallergic and antiemetic drugs	0.321	0.679	0.000
S62.2 Fracture of first metacarpal bone	0.320	0.680	0.000
S52.10 Fracture of upper end of radius (closed)	0.320	0.680	0.000
S90-S99 Injuries to the ankle and foot	0.318	0.682	0.000
S58 Traumatic amputation of forearm	0.316	0.684	0.000
S57 Crushing injury of forearm	0.316	0.684	0.000
S55 Injury of blood vessels at forearm level	0.316	0.684	0.000
S31 Open wound of abdomen, lower back and pelvis	0.315	0.684	0.000
T82.3 Mechanical complication of other vascular grafts	0.314	0.686	0.000
T09 Other injuries of spine and trunk, level unspecified	0.314	0.686	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.313	0.686	0.000
S62.1 Fracture of other carpal bone(s)	0.313	0.687	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.312	0.688	0.000
S62.7 Multiple fractures of fingers	0.312	0.688	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.311	0.688	0.000
S48 Traumatic amputation of shoulder and upper arm	0.311	0.689	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.311	0.689	0.000
S44 Injury of nerves at shoulder and upper arm level	0.311	0.689	0.000
S47 Crushing injury of shoulder and upper arm	0.311	0.689	0.000
S10-S19 Injuries to the neck	0.311	0.689	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.310	0.690	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.310	0.690	0.000
T13 Other injuries of lower limb, level unspecified	0.309	0.691	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.309	0.691	0.000
T93.2 Sequelae of other fractures of lower limb	0.308	0.692	0.000
S56.7 Injury of multiple muscles and tendons at forearm level	0.305	0.695	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.305	0.695	0.000
S62.4 Multiple fractures of metacarpal bones	0.304	0.696	0.000
T23 Burn and corrosion of wrist and hand	0.304	0.696	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.304	0.696	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.304	0.696	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.304	0.696	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.304	0.696	0.000
S64 Injury of nerves at wrist and hand level	0.302	0.698	0.000
T14 Injury of unspecified body region	0.302	0.698	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.302	0.698	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.302	0.698	0.000
S27.0 Traumatic pneumothorax	0.302	0.698	0.000
S62.5 Fracture of thumb	0.300	0.700	0.000
S22.4 Multiple fractures of ribs	0.299	0.701	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.299	0.701	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.299	0.701	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.298	0.702	0.000
S22.3 Fracture of rib	0.297	0.703	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.297	0.703	0.000
T92.1 Sequelae of fracture of arm	0.297	0.703	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.296	0.704	0.000
S22.2 Fracture of sternum	0.296	0.704	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.296	0.704	0.000
S42.0 Fracture of clavicle	0.295	0.705	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.295	0.705	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.295	0.705	0.000
S26 Injury of heart	0.295	0.705	0.000
S25 Injury of blood vessels of thorax	0.295	0.705	0.000
S24 Injury of nerves and spinal cord at thorax level	0.295	0.705	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.295	0.705	0.000
S21 Open wound of thorax	0.295	0.705	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.295	0.705	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.295	0.705	0.000
T12 Fracture of lower limb, level unspecified	0.295	0.705	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.295	0.705	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.295	0.705	0.000
T10 Fracture of upper limb, level unspecified	0.295	0.705	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.295	0.705	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.295	0.705	0.000
T08 Fracture of spine, level unspecified	0.295	0.705	0.000
T56 Toxic effect of metals	0.294	0.706	0.000
T25 Burn and corrosion of ankle and foot	0.294	0.706	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.294	0.706	0.000
T86.0 Bone-marrow transplant rejection	0.294	0.706	0.000
S40.0 Contusion of shoulder and upper arm	0.293	0.707	0.000
T93.0 Sequelae of open wound of lower limb	0.293	0.707	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.292	0.707	0.000
T21 Burn and corrosion of trunk	0.292	0.708	0.000
T01 Open wounds involving multiple body regions	0.290	0.709	0.000
T79-T79 Certain early complications of trauma	0.290	0.710	0.000
S36 Injury of intra-abdominal organs	0.288	0.712	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.287	0.712	0.000
T45.5 Anticoagulants	0.286	0.713	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.286	0.714	0.000
T86.4 Liver transplant failure and rejection	0.286	0.714	0.000
T86.3 Heart-lung transplant failure and rejection	0.286	0.714	0.000
T86.2 Heart transplant failure and rejection	0.286	0.714	0.000
T59 Toxic effect of other gases, fumes and vapours	0.286	0.714	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.285	0.715	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.284	0.716	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.284	0.716	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.284	0.716	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.281	0.718	0.000
T45.8 Other primarily systemic and haematological agents	0.281	0.718	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.281	0.718	0.000
T45.6 Fibrinolysis-affecting drugs	0.281	0.718	0.000
T45.4 Iron and its compounds	0.281	0.718	0.000
T45.3 Enzymes, not elsewhere classified	0.281	0.718	0.000
T45.2 Vitamins, not elsewhere classified	0.281	0.718	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.280	0.720	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.279	0.721	0.000
T37.5 Antiviral drugs	0.279	0.721	0.000
T37.4 Anthelminthics	0.279	0.721	0.000
T37.3 Other antiprotozoal drugs	0.279	0.721	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.279	0.721	0.000
T37.1 Antimycobacterial drugs	0.279	0.721	0.000
T37.0 Sulphonamides	0.279	0.721	0.000
S32.5 Fracture of pubis	0.279	0.721	0.000
T91 Sequelae of injuries of neck and trunk	0.279	0.721	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.279	0.721	0.000
S52.2 Fracture of shaft of ulna	0.279	0.721	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.279	0.721	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.279	0.721	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.278	0.722	0.000
T38.9 Other and unspecified hormone antagonists	0.278	0.722	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.278	0.722	0.000
T38.7 Androgens and anabolic congeners	0.278	0.722	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.278	0.722	0.000
T38.5 Other oestrogens and progestogens	0.278	0.722	0.000
T38.4 Oral contraceptives	0.278	0.722	0.000
T38.2 Antithyroid drugs	0.278	0.722	0.000
T38.1 Thyroid hormones and substitutes	0.278	0.722	0.000
T38.0 Glucocorticoids and synthetic analogues	0.278	0.722	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.277	0.723	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.277	0.723	0.000
S37 Injury of urinary and pelvic organs	0.277	0.723	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.277	0.723	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.277	0.723	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.277	0.723	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.277	0.723	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.276	0.724	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.276	0.724	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.276	0.724	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.276	0.724	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.276	0.724	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.276	0.724	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.276	0.724	0.000
T44.0 Anticholinesterase agents	0.276	0.724	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.276	0.724	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.276	0.724	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.276	0.724	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.275	0.724	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.275	0.724	0.000
T47.7 Emetics	0.275	0.724	0.000
T47.6 Antidiarrhoeal drugs	0.275	0.724	0.000
T47.5 Digestants	0.275	0.724	0.000
T47.4 Other laxatives	0.275	0.724	0.000
T47.3 Saline and osmotic laxatives	0.275	0.724	0.000
T47.2 Stimulant laxatives	0.275	0.724	0.000
T47.0 Histamine H(2)-receptor antagonists	0.275	0.724	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.275	0.725	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.275	0.725	0.000
T46.7 Peripheral vasodilators	0.275	0.725	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.275	0.725	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.275	0.725	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.275	0.725	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.275	0.725	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.275	0.725	0.000
T50.4 Drugs affecting uric acid metabolism	0.275	0.725	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.273	0.726	0.000
T94.1 Sequelae of injuries, not specified by body region	0.273	0.727	0.000
S56.2 Injury of other flexor muscle and tendon at forearm level	0.273	0.727	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.273	0.727	0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.273	0.727	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.273	0.727	0.000
S51 Open wound of forearm	0.273	0.727	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.272	0.727	0.000
S42.10 Fracture of scapula (closed)	0.272	0.728	0.000
T87.6 Other and unspecified complications of amputation stump	0.272	0.728	0.000
T46.1 Calcium-channel blockers	0.272	0.728	0.000
S67 Crushing injury of wrist and hand	0.271	0.728	0.000
T00 Superficial injuries involving multiple body regions	0.271	0.729	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.269	0.730	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.269	0.730	0.000
S69.8 Other specified injuries of wrist and hand	0.269	0.731	0.000
S69.7 Multiple injuries of wrist and hand	0.269	0.731	0.000
T20.0 Burn of unspecified degree of head and neck	0.268	0.731	0.000
T20.2 Burn of second degree of head and neck	0.268	0.732	0.000
S63.5 Sprain and strain of wrist	0.268	0.732	0.000
S29 Other and unspecified injuries of thorax	0.267	0.732	0.000
T98.2 Sequelae of certain early complications of trauma	0.267	0.733	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.267	0.733	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.267	0.733	0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.265	0.735	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.265	0.735	0.000
T05 Traumatic amputations involving multiple body regions	0.265	0.735	0.000
T04 Crushing injuries involving multiple body regions	0.265	0.735	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.265	0.735	0.000
T07 Unspecified multiple injuries	0.265	0.735	0.000
T92.0 Sequelae of open wound of upper limb	0.264	0.736	0.000
S41 Open wound of shoulder and upper arm	0.264	0.736	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.264	0.736	0.000
T80.6 Other serum reactions	0.264	0.736	0.000
T80.5 Anaphylactic shock due to serum	0.264	0.736	0.000
T80.4 Rh incompatibility reaction	0.264	0.736	0.000
T80.3 ABO incompatibility reaction	0.264	0.736	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.264	0.736	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.264	0.736	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.263	0.737	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.263	0.737	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.263	0.737	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.263	0.737	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.263	0.737	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.263	0.737	0.000
T20.1 Burn of first degree of head and neck	0.263	0.737	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.262	0.738	0.000
T11.0 Superficial injury of upper limb, level unspecified	0.262	0.738	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.262	0.738	0.000
S42.3 Fracture of shaft of humerus	0.262	0.738	0.000
T86.1 Kidney transplant failure and rejection	0.262	0.738	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.261	0.738	0.000
T87.4 Infection of amputation stump	0.261	0.739	0.000
T65 Toxic effect of other and unspecified substances	0.259	0.741	0.000
T62 Toxic effect of other noxious substances eaten as food	0.259	0.741	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.259	0.741	0.000
T60 Toxic effect of pesticides	0.259	0.741	0.000
T57 Toxic effect of other inorganic substances	0.259	0.741	0.000
T54 Toxic effect of corrosive substances	0.259	0.741	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.259	0.741	0.000
T52 Toxic effect of organic solvents	0.259	0.741	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.259	0.741	0.000
T58 Toxic effect of carbon monoxide	0.259	0.741	0.000
T55 Toxic effect of soaps and detergents	0.259	0.741	0.000
S54.1 Injury of median nerve at forearm level	0.258	0.741	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.257	0.742	0.000
S42.21 Fracture of upper end of humerus (open)	0.257	0.742	0.000
S22.9 Fracture of bony thorax, part unspecified	0.257	0.743	0.000
S22.8 Fracture of other parts of bony thorax	0.257	0.743	0.000
S59.9 Unspecified injury of forearm	0.257	0.743	0.000
S22.40 Multiple fractures of ribs (closed)	0.257	0.743	0.000
T87.5 Necrosis of amputation stump	0.255	0.744	0.000
T87.3 Neuroma of amputation stump	0.255	0.744	0.000
T87.2 Complications of other reattached body part	0.255	0.744	0.000
T87.1 Complications of reattached (part of) lower extremity	0.255	0.744	0.000
T87.0 Complications of reattached (part of) upper extremity	0.255	0.744	0.000
T41.5 Therapeutic gases	0.255	0.745	0.000
T41.4 Anaesthetic, unspecified	0.255	0.745	0.000
T41.3 Local anaesthetics	0.255	0.745	0.000
T41.2 Other and unspecified general anaesthetics	0.255	0.745	0.000
T41.1 Intravenous anaesthetics	0.255	0.745	0.000
T41.0 Inhaled anaesthetics	0.255	0.745	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.255	0.745	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.255	0.745	0.000
T48.5 Anti-common-cold drugs	0.255	0.745	0.000
T48.4 Expectorants	0.255	0.745	0.000
T48.3 Antitussives	0.255	0.745	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.255	0.745	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.255	0.745	0.000
T48.0 Oxytocic drugs	0.255	0.745	0.000
T49.9 Topical agent, unspecified	0.255	0.745	0.000
T49.8 Other topical agents	0.255	0.745	0.000
T49.7 Dental drugs, topically applied	0.255	0.745	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.255	0.745	0.000
T49.5 Ophthalmological drugs and preparations	0.255	0.745	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.255	0.745	0.000
T49.3 Emollients, demulcents and protectants	0.255	0.745	0.000
T49.2 Local astringents and local detergents	0.255	0.745	0.000
T49.1 Antipruritics	0.255	0.745	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.255	0.745	0.000
S32.3 Fracture of ilium	0.255	0.745	0.000
S20 Superficial injury of thorax	0.254	0.745	0.000
T28 Burn and corrosion of other internal organs	0.254	0.746	0.000
T27 Burn and corrosion of respiratory tract	0.254	0.746	0.000
T26 Burn and corrosion confined to eye and adnexa	0.254	0.746	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.254	0.746	0.000
T34 Frostbite with tissue necrosis	0.254	0.746	0.000
T33 Superficial frostbite	0.254	0.746	0.000
S22.30 Fracture of rib (closed)	0.253	0.747	0.000
S22.0 Fracture of thoracic vertebra	0.253	0.747	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.253	0.747	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.252	0.748	0.000
S52.9 Fracture of forearm, part unspecified	0.252	0.748	0.000
S52.3 Fracture of shaft of radius	0.252	0.748	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.251	0.748	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.251	0.749	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.251	0.749	0.000
S22.20 Fracture of sternum (closed)	0.250	0.750	0.000
T36.9 Systemic antibiotic, unspecified	0.250	0.750	0.000
T36.8 Other systemic antibiotics	0.250	0.750	0.000
T36.7 Antifungal antibiotics, systemically used	0.250	0.750	0.000
T36.6 Rifamycins	0.250	0.750	0.000
T36.5 Aminoglycosides	0.250	0.750	0.000
T36.4 Tetracyclines	0.250	0.750	0.000
T36.3 Macrolides	0.250	0.750	0.000
T36.2 Chloramphenicol group	0.250	0.750	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.250	0.750	0.000
S22.5 Flail chest	0.250	0.750	0.000
T50.8 Diagnostic agents	0.249	0.751	0.000
T50.7 Analeptics and opioid receptor antagonists	0.249	0.751	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.249	0.751	0.000
T50.5 Appetite depressants	0.249	0.751	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.249	0.751	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.249	0.751	0.000
T50.1 Loop [high-ceiling] diuretics	0.249	0.751	0.000
T50.0 Mineralocorticoids and their antagonists	0.249	0.751	0.000
S90 Superficial injury of ankle and foot	0.249	0.751	0.000
S50.0 Contusion of elbow	0.249	0.751	0.000
S54.0 Injury of ulnar nerve at forearm level	0.249	0.751	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.249	0.751	0.000
S63.1 Dislocation finger	0.248	0.752	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.248	0.752	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.248	0.752	0.000
S63.2 Multiple dislocations of fingers	0.248	0.752	0.000
S63.0 Dislocation of wrist	0.247	0.753	0.000
T20.7 Corrosion of third degree of head and neck	0.246	0.754	0.000
T20.6 Corrosion of second degree of head and neck	0.246	0.754	0.000
T20.5 Corrosion of first degree of head and neck	0.246	0.754	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.246	0.754	0.000
T20.3 Burn of third degree of head and neck	0.246	0.754	0.000
T56.8 Other metals	0.246	0.754	0.000
T02 Fractures involving multiple body regions	0.246	0.754	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.246	0.754	0.000
S65.5 Injury of blood vessel(s) of other finger	0.245	0.754	0.000
S32.50 Fracture of pubis (closed)	0.245	0.754	0.000
S52.8 Fracture of other parts of forearm	0.245	0.755	0.000
T09.0 Superficial injury of trunk, level unspecified	0.244	0.756	0.000
S32.1 Fracture of sacrum	0.244	0.756	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.244	0.756	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.244	0.756	0.000
T36.0 Penicillins	0.242	0.757	0.000
S54.2 Injury of radial nerve at forearm level	0.242	0.758	0.000
S54.9 Injury of unspecified nerve at forearm level	0.242	0.758	0.000
S54.8 Injury of other nerves at forearm level	0.242	0.758	0.000
S54.7 Injury of multiple nerves at forearm level	0.242	0.758	0.000
S54.3 Injury of cutaneous sensory nerve at forearm level	0.242	0.758	0.000
S52.4 Fracture of shafts of both ulna and radius	0.241	0.758	0.000
S60 Superficial injury of wrist and hand	0.241	0.759	0.000
S42.4 Fracture of lower end of humerus	0.240	0.760	0.000
T32 Corrosions classified according to extent of body surface involved	0.239	0.760	0.000
T30 Burn and corrosion, body region unspecified	0.239	0.760	0.000
T29 Burns and corrosions of multiple body regions	0.239	0.760	0.000
S59.8 Other specified injuries of forearm	0.239	0.760	0.000
S59.7 Multiple injuries of forearm	0.239	0.760	0.000
S52.11 Fracture of upper end of radius (open)	0.238	0.761	0.000
S27.1 Traumatic haemothorax	0.238	0.762	0.000
S27.9 Injury of unspecified intrathoracic organ	0.238	0.762	0.000
S27.8 Injury of other specified intrathoracic organs	0.238	0.762	0.000
S27.7 Multiple injuries of intrathoracic organs	0.238	0.762	0.000
S27.6 Injury of pleura	0.238	0.762	0.000
S27.5 Injury of thoracic trachea	0.238	0.762	0.000
S27.4 Injury of bronchus	0.238	0.762	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.236	0.763	0.000
S50.9 Superficial injury of forearm, unspecified	0.236	0.763	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.236	0.764	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.235	0.764	0.000
S50.7 Multiple superficial injuries of forearm	0.235	0.764	0.000
S50.1 Contusion of other and unspecified parts of forearm	0.235	0.764	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.235	0.765	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.235	0.765	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.235	0.765	0.000
S65.4 Injury of blood vessel(s) of thumb	0.235	0.765	0.000
S65.3 Injury of deep palmar arch	0.235	0.765	0.000
S65.2 Injury of superficial palmar arch	0.235	0.765	0.000
S65.1 Injury of radial artery at wrist and hand level	0.235	0.765	0.000
S65.0 Injury of ulnar artery at wrist and hand level	0.235	0.765	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.235	0.765	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.234	0.765	0.000
S32.2 Fracture of coccyx	0.234	0.765	0.000
S62.70 Multiple fractures of fingers (closed)	0.234	0.766	0.000
T01.2 Open wounds involving multiple regions of upper limb(s)	0.234	0.766	0.000
S62.51 Fracture of thumb (open)	0.233	0.767	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.233	0.767	0.000
S50.8 Other superficial injuries of forearm	0.233	0.767	0.000
S31.1 Open wound of abdominal wall	0.233	0.767	0.000
S52.7 Multiple fractures of forearm	0.233	0.767	0.000
T11.9 Unspecified injury of upper limb, level unspecified	0.232	0.767	0.000
T11.8 Other specified injuries of upper limb, level unspecified	0.232	0.767	0.000
T11.6 Traumatic amputation of upper limb, level unspecified	0.232	0.767	0.000
T11.5 Injury of unspecified muscle and tendon of upper limb, level unspecified	0.232	0.767	0.000
T11.4 Injury of unspecified blood vessel of upper limb, level unspecified	0.232	0.767	0.000
T11.3 Injury of unspecified nerve of upper limb, level unspecified	0.232	0.767	0.000
T11.2 Dislocation, strain and sprain of unspecified joint and ligament of upper limb, level unspecified	0.232	0.767	0.000
T11.1 Open wound of upper limb, level unspecified	0.232	0.767	0.000
T59.8 Other specified gases, fumes and vapours	0.233	0.767	0.000
S42.11 Fracture of scapula (open)	0.232	0.767	0.000
T66-T78 Other and unspecified effects of external causes	0.232	0.768	0.000
T14.6 Injury of tendons and muscles of unspecified body region	0.231	0.769	0.000
S32.0 Fracture of lumbar vertebra	0.231	0.769	0.000
S62.21 Fracture of first metacarpal bone (open)	0.230	0.770	0.000
T14.1 Open wound of unspecified body region	0.229	0.770	0.000
S10 Superficial injury of neck	0.229	0.770	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.229	0.770	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.228	0.771	0.001
T63 Toxic effect of contact with venomous animals	0.229	0.771	0.000
S98 Traumatic amputation of ankle and foot	0.228	0.772	0.000
S97 Crushing injury of ankle and foot	0.228	0.772	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations