TreeWAS – Variant ID: rs611705

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.069	0.931
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.077	0.923
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.078	0.922
T50.9 Other and unspecified drugs, medicaments and biological substances	0.085	0.915
T43.2 Other and unspecified antidepressants	0.105	0.895
T46 Poisoning by agents primarily affecting the cardiovascular system	0.126	0.874
T46.4 Angiotensin-converting-enzyme inhibitors	0.173	0.827
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.193	0.807
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.195	0.805
T43.0 Tricyclic and tetracyclic antidepressants	0.197	0.803
T43.5 Other and unspecified antipsychotics and neuroleptics	0.202	0.798
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.233	0.767
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.244	0.756
T47.1 Other antacids and anti-gastric-secretion drugs	0.256	0.744
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.267	0.733
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.268	0.732
T50.6 Antidotes and chelating agents, not elsewhere classified	0.274	0.726
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.282	0.718
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.289	0.711
T43.4 Butyrophenone and thioxanthene neuroleptics	0.291	0.709
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.308	0.692
T50.1 Loop [high-ceiling] diuretics	0.309	0.691
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.310	0.690
T50.4 Drugs affecting uric acid metabolism	0.320	0.680
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.321	0.679
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.327	0.673
T43.6 Psychostimulants with abuse potential	0.330	0.670
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.333	0.667
T43.8 Other psychotropic drugs, not elsewhere classified	0.338	0.662
T46.3 Coronary vasodilators, not elsewhere classified	0.339	0.661
T50.7 Analeptics and opioid receptor antagonists	0.339	0.661
T50.5 Appetite depressants	0.339	0.661
T50.3 Electrolytic, caloric and water-balance agents	0.339	0.661
T50.0 Mineralocorticoids and their antagonists	0.339	0.661
T42.3 Barbiturates	0.345	0.655
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.360	0.640
T41 Poisoning by anaesthetics and therapeutic gases	0.362	0.637
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.366	0.634
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.371	0.629
T46.8 Antivaricose drugs, including sclerosing agents	0.374	0.626
T46.7 Peripheral vasodilators	0.374	0.626
T50.8 Diagnostic agents	0.375	0.625
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.385	0.615
T36 Poisoning by systemic antibiotics	0.389	0.611
T43.3 Phenothiazine antipsychotics and neuroleptics	0.392	0.608
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.395	0.604
T46.5 Other antihypertensive drugs, not elsewhere classified	0.397	0.603
T43.9 Psychotropic drug, unspecified	0.398	0.601
T46.1 Calcium-channel blockers	0.402	0.598
T40.2 Other opioids	0.402	0.598
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.403	0.597
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.404	0.596
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.404	0.596
T42.0 Hydantoin derivatives	0.407	0.593
T40.5 Cocaine	0.412	0.588
T45.2 Vitamins, not elsewhere classified	0.413	0.587
T47.4 Other laxatives	0.415	0.585
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.420	0.580
T47.0 Histamine H(2)-receptor antagonists	0.420	0.580
T45.1 Antineoplastic and immunosuppressive drugs	0.421	0.579
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.421	0.579
T47.8 Other agents primarily affecting the gastro-intestinal system	0.421	0.579
T47.7 Emetics	0.421	0.579
T47.5 Digestants	0.421	0.579
T47.3 Saline and osmotic laxatives	0.421	0.579
T42.5 Mixed antiepileptics, not elsewhere classified	0.423	0.577
T42.2 Succinimides and oxazolidinediones	0.423	0.577
T45.0 Antiallergic and antiemetic drugs	0.428	0.572
T38.0 Glucocorticoids and synthetic analogues	0.432	0.568
T40.1 Heroin	0.434	0.566
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.437	0.563
T47.6 Antidiarrhoeal drugs	0.449	0.551
T39.4 Antirheumatics, not elsewhere classified	0.450	0.550
T39.2 Pyrazolone derivatives	0.450	0.550
T42.4 Benzodiazepines	0.453	0.547
T45.9 Primarily systemic and haematological agent, unspecified	0.458	0.542
T45.8 Other primarily systemic and haematological agents	0.458	0.542
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.458	0.542
T45.6 Fibrinolysis-affecting drugs	0.458	0.542
T45.4 Iron and its compounds	0.458	0.542
T45.3 Enzymes, not elsewhere classified	0.458	0.542
T38.5 Other oestrogens and progestogens	0.466	0.534
T45.5 Anticoagulants	0.468	0.532
T38.8 Other and unspecified hormones and their synthetic substitutes	0.468	0.531
T38.1 Thyroid hormones and substitutes	0.474	0.525
T38.9 Other and unspecified hormone antagonists	0.475	0.525
T38.7 Androgens and anabolic congeners	0.475	0.525
T38.4 Oral contraceptives	0.475	0.525
T38.2 Antithyroid drugs	0.475	0.525
T48.5 Anti-common-cold drugs	0.475	0.525
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.478	0.522
T39.0 Salicylates	0.482	0.518
T47.2 Stimulant laxatives	0.485	0.515
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.485	0.515
T40.8 Lysergide [LSD]	0.485	0.515
T40.7 Cannabis (derivatives)	0.485	0.515
T40.0 Opium	0.485	0.515
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.492	0.508
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.496	0.504
T42.1 Iminostilbenes	0.496	0.504
T49.9 Topical agent, unspecified	0.503	0.496
T49.8 Other topical agents	0.503	0.496
T49.7 Dental drugs, topically applied	0.503	0.496
T49.6 Otorhinolaryngological drugs and preparations	0.503	0.496
T49.5 Ophthalmological drugs and preparations	0.503	0.496
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.503	0.496
T49.3 Emollients, demulcents and protectants	0.503	0.496
T49.2 Local astringents and local detergents	0.503	0.496
T49.1 Antipruritics	0.503	0.496
T40.3 Methadone	0.504	0.496
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.505	0.494
T48.4 Expectorants	0.505	0.494
T48.3 Antitussives	0.505	0.494
T48.2 Other and unspecified agents primarily acting on muscles	0.505	0.494
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.505	0.494
T48.0 Oxytocic drugs	0.505	0.494
T48.6 Antiasthmatics, not elsewhere classified	0.515	0.485
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.517	0.483
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.517	0.483
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.517	0.483
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.517	0.483
T44.1 Other parasympathomimetics [cholinergics]	0.517	0.483
T44.0 Anticholinesterase agents	0.517	0.483
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.521	0.479
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.528	0.471
T41.5 Therapeutic gases	0.543	0.457
T41.4 Anaesthetic, unspecified	0.543	0.457
T41.3 Local anaesthetics	0.543	0.457
T41.1 Intravenous anaesthetics	0.543	0.457
T41.0 Inhaled anaesthetics	0.543	0.457
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.545	0.454
T37.5 Antiviral drugs	0.545	0.454
T37.4 Anthelminthics	0.545	0.454
T37.3 Other antiprotozoal drugs	0.545	0.454
T37.1 Antimycobacterial drugs	0.545	0.454
T37.0 Sulphonamides	0.545	0.454
T36.4 Tetracyclines	0.551	0.448
T36.3 Macrolides	0.557	0.443
T37.2 Antimalarials and drugs acting on other blood protozoa	0.561	0.438
T37.8 Other specified systemic anti-infectives and antiparasitics	0.562	0.438
T36.9 Systemic antibiotic, unspecified	0.562	0.438
T36.7 Antifungal antibiotics, systemically used	0.562	0.438
T36.6 Rifamycins	0.562	0.438
T36.5 Aminoglycosides	0.562	0.438
T36.2 Chloramphenicol group	0.562	0.438
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.563	0.437
T39.1 4-Aminophenol derivatives	0.571	0.429
T41.2 Other and unspecified general anaesthetics	0.572	0.427
T36.8 Other systemic antibiotics	0.578	0.422
T40.6 Other and unspecified narcotics	0.581	0.418
T36.0 Penicillins	0.587	0.413
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.591	0.408
T40.4 Other synthetic narcotics	0.620	0.380
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.750	0.250
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.750	0.250
T18 Foreign body in alimentary tract	0.751	0.249
T18.1 Foreign body in oesophagus	0.752	0.248
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.752	0.248
T15-T19 Effects of foreign body entering through natural orifice	0.752	0.248
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.758	0.242
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.768	0.232
T00-T07 Injuries involving multiple body regions	0.774	0.226
S60-S69 Injuries to the wrist and hand	0.776	0.224
T80 Complications following infusion, transfusion and therapeutic injection	0.780	0.220
T86 Failure and rejection of transplanted organs and tissues	0.781	0.219
S90-S99 Injuries to the ankle and foot	0.783	0.217
S60 Superficial injury of wrist and hand	0.783	0.217
T85 Complications of other internal prosthetic devices, implants and grafts	0.784	0.216
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.789	0.211
T87 Complications peculiar to reattachment and amputation	0.795	0.204
S60.9 Superficial injury of wrist and hand, unspecified	0.797	0.203
T00 Superficial injuries involving multiple body regions	0.798	0.202
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.800	0.200
T18.0 Foreign body in mouth	0.800	0.200
S64 Injury of nerves at wrist and hand level	0.800	0.200
T16 Foreign body in ear	0.803	0.197
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.803	0.197
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.810	0.190
S96 Injury of muscle and tendon at ankle and foot level	0.813	0.187
T86.8 Failure and rejection of other transplanted organs and tissues	0.814	0.186
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.814	0.186
T83.0 Mechanical complication of urinary (indwelling) catheter	0.815	0.185
T18.9 Foreign body in alimentary tract, part unspecified	0.816	0.184
T83.2 Mechanical complication of graft of urinary organ	0.816	0.184
T18.3 Foreign body in small intestine	0.816	0.184
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.816	0.184
S62 Fracture at wrist and hand level	0.819	0.181
T18.5 Foreign body in anus and rectum	0.819	0.181
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.819	0.181
T26-T28 Burns and corrosions confined to eye and internal organs	0.820	0.180
T33-T35 Frostbite	0.821	0.179
T86.0 Bone-marrow transplant rejection	0.821	0.179
T19 Foreign body in genito-urinary tract	0.821	0.179
T18.8 Foreign body in other and multiple parts of alimentary tract	0.822	0.178
T18.4 Foreign body in colon	0.822	0.178
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.822	0.178
S92 Fracture of foot, except ankle	0.822	0.178
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.823	0.177
S60.2 Contusion of other parts of wrist and hand	0.824	0.176
S64.1 Injury of median nerve at wrist and hand level	0.824	0.176
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.824	0.176
S60.7 Multiple superficial injuries of wrist and hand	0.824	0.176
T01 Open wounds involving multiple body regions	0.824	0.175
T83.3 Mechanical complication of intra-uterine contraceptive device	0.825	0.175
T15 Foreign body on external eye	0.825	0.175
S91 Open wound of ankle and foot	0.825	0.175
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.827	0.173
S64.0 Injury of ulnar nerve at wrist and hand level	0.828	0.172
T02 Fractures involving multiple body regions	0.828	0.172
S60.0 Contusion of finger(s) without damage to nail	0.828	0.172
T00.9 Multiple superficial injuries, unspecified	0.829	0.171
S66 Injury of muscle and tendon at wrist and hand level	0.829	0.170
S98 Traumatic amputation of ankle and foot	0.830	0.170
T18.2 Foreign body in stomach	0.831	0.169
T87.6 Other and unspecified complications of amputation stump	0.831	0.169
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.831	0.169
T79-T79 Certain early complications of trauma	0.831	0.169
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.833	0.167
S64.3 Injury of digital nerve of thumb	0.833	0.167
T88 Other complications of surgical and medical care, not elsewhere classified	0.833	0.167
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.834	0.166
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.837	0.163
T05 Traumatic amputations involving multiple body regions	0.838	0.162
T04 Crushing injuries involving multiple body regions	0.838	0.162
T03 Dislocations, sprains and strains involving multiple body regions	0.838	0.162
T07 Unspecified multiple injuries	0.838	0.162
S68 Traumatic amputation of wrist and hand	0.838	0.162
S62.3 Fracture of other metacarpal bone	0.838	0.162
S69 Other and unspecified injuries of wrist and hand	0.838	0.162
T87.4 Infection of amputation stump	0.838	0.162
T00.8 Superficial injuries involving other combinations of body regions	0.840	0.160
T06 Other injuries involving multiple body regions, not elsewhere classified	0.842	0.158
T86.4 Liver transplant failure and rejection	0.842	0.158
T80.6 Other serum reactions	0.842	0.158
T80.5 Anaphylactic shock due to serum	0.842	0.158
T80.4 Rh incompatibility reaction	0.842	0.158
T80.3 ABO incompatibility reaction	0.842	0.158
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.842	0.158
T86.3 Heart-lung transplant failure and rejection	0.842	0.157
T86.2 Heart transplant failure and rejection	0.842	0.157
S20-S29 Injuries to the thorax	0.843	0.156
S95 Injury of blood vessels at ankle and foot level	0.844	0.156
S94 Injury of nerves at ankle and foot level	0.844	0.156
S92.3 Fracture of metatarsal bone	0.844	0.156
S99 Other and unspecified injuries of ankle and foot	0.844	0.156
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.845	0.155
S60.8 Other superficial injuries of wrist and hand	0.846	0.154
S64.7 Injury of multiple nerves at wrist and hand level	0.847	0.153
S62.30 Fracture of other metacarpal bone (closed)	0.848	0.152
T66-T78 Other and unspecified effects of external causes	0.849	0.151
T00.2 Superficial injuries involving multiple regions of upper limb(s)	0.850	0.150
S96.8 Injury of other muscles and tendons at ankle and foot level	0.850	0.150
S91.2 Open wound of toe(s) with damage to nail	0.851	0.149
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.853	0.147
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.853	0.147
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.853	0.147
T87.2 Complications of other reattached body part	0.853	0.147
T87.1 Complications of reattached (part of) lower extremity	0.853	0.147
T87.0 Complications of reattached (part of) upper extremity	0.853	0.147
S65 Injury of blood vessels at wrist and hand level	0.853	0.147
S91.3 Open wound of other parts of foot	0.853	0.147
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.854	0.146
S62.6 Fracture of other finger	0.854	0.146
T17 Foreign body in respiratory tract	0.854	0.145
T00.1 Superficial injuries involving thorax with abdomen, lower back and pelvis	0.855	0.145
T00.0 Superficial injuries involving head with neck	0.855	0.145
S60.1 Contusion of finger(s) with damage to nail	0.855	0.144
T86.1 Kidney transplant failure and rejection	0.856	0.144
S64.9 Injury of unspecified nerve at wrist and hand level	0.857	0.143
S64.8 Injury of other nerves at wrist and hand level	0.857	0.143
S67 Crushing injury of wrist and hand	0.857	0.143
S97 Crushing injury of ankle and foot	0.857	0.142
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.858	0.142
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.858	0.142
T87.3 Neuroma of amputation stump	0.858	0.141
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.859	0.141
S27 Injury of other and unspecified intrathoracic organs	0.859	0.141
S62.2 Fracture of first metacarpal bone	0.859	0.141
S92.30 Fracture of metatarsal bone (closed)	0.860	0.140
S62.8 Fracture of other and unspecified parts of wrist and hand	0.860	0.140
T20-T25 Burns and corrosions of external body surface, specified by site	0.860	0.140
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.861	0.139
T87.5 Necrosis of amputation stump	0.861	0.139
T01.8 Open wounds involving other combinations of body regions	0.861	0.139
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.861	0.138
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.862	0.138
S98.1 Traumatic amputation of one toe	0.863	0.137
T00.6 Superficial injuries involving multiple regions of upper limb(s) with lower limb(s)	0.863	0.136
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.864	0.136
T29 Burns and corrosions of multiple body regions	0.866	0.134
T19.0 Foreign body in urethra	0.866	0.134
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.866	0.134
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.866	0.134
T02.8 Fractures involving other combinations of body regions	0.866	0.134
T15.0 Foreign body in cornea	0.866	0.133
T88.9 Complication of surgical and medical care, unspecified	0.866	0.134
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.867	0.133
S92.2 Fracture of other tarsal bone(s)	0.867	0.133
T19.2 Foreign body in vulva and vagina	0.867	0.133
S68.0 Traumatic amputation of thumb (complete)(partial)	0.867	0.133
T59 Toxic effect of other gases, fumes and vapours	0.869	0.131
T26 Burn and corrosion confined to eye and adnexa	0.869	0.131
S92.9 Fracture of foot, unspecified	0.869	0.131
S92.5 Fracture of other toe	0.869	0.131
T85.2 Mechanical complication of intraocular lens	0.870	0.130
T28 Burn and corrosion of other internal organs	0.870	0.129
T27 Burn and corrosion of respiratory tract	0.870	0.129
T02.4 Fractures involving multiple regions of both upper limbs	0.870	0.129
T30 Burn and corrosion, body region unspecified	0.870	0.129
S62.7 Multiple fractures of fingers	0.871	0.129
T35 Frostbite involving multiple body regions and unspecified frostbite	0.871	0.128
T34 Frostbite with tissue necrosis	0.871	0.128
T33 Superficial frostbite	0.871	0.128
T19.9 Foreign body in genito-urinary tract, part unspecified	0.872	0.128
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.872	0.128
T19.3 Foreign body in uterus [any part]	0.872	0.128
S90 Superficial injury of ankle and foot	0.872	0.128
T01.3 Open wounds involving multiple regions of lower limb(s)	0.872	0.128
S92.7 Multiple fractures of foot	0.872	0.128
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.873	0.127
T32 Corrosions classified according to extent of body surface involved	0.873	0.126
T01.9 Multiple open wounds, unspecified	0.874	0.126
T01.6 Open wounds involving multiple regions of upper limb(s) with lower limb(s)	0.874	0.126
T01.1 Open wounds involving thorax with abdomen, lower back and pelvis	0.874	0.126
T01.0 Open wounds involving head with neck	0.874	0.126
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.874	0.126
T15.8 Foreign body in other and multiple parts of external eye	0.874	0.125
S91.7 Multiple open wounds of ankle and foot	0.875	0.125
T01.2 Open wounds involving multiple regions of upper limb(s)	0.875	0.125
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.876	0.124
S92.4 Fracture of great toe	0.876	0.124
T83.1 Mechanical complication of other urinary devices and implants	0.876	0.124
S10-S19 Injuries to the neck	0.876	0.124
T02.9 Multiple fractures, unspecified	0.877	0.123
T02.7 Fractures involving thorax with lower back and pelvis with limb(s)	0.877	0.123
T02.6 Fractures involving multiple regions of upper limb(s) with lower limb(s)	0.877	0.123
T02.3 Fractures involving multiple regions of one lower limb	0.877	0.123
T02.1 Fractures involving thorax with lower back and pelvis	0.877	0.123
T02.0 Fractures involving head with neck	0.877	0.123
S69.7 Multiple injuries of wrist and hand	0.877	0.123
T88.7 Unspecified adverse effect of drug or medicament	0.877	0.123
S92.1 Fracture of talus	0.877	0.123
T63 Toxic effect of contact with venomous animals	0.877	0.123
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.878	0.122
S98.4 Traumatic amputation of foot, level unspecified	0.878	0.122
S98.3 Traumatic amputation of other parts of foot	0.878	0.122
S98.2 Traumatic amputation of two or more toes	0.878	0.122
S98.0 Traumatic amputation of foot at ankle level	0.878	0.122
S62.1 Fracture of other carpal bone(s)	0.878	0.122
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.878	0.122
T54 Toxic effect of corrosive substances	0.878	0.122
T15.1 Foreign body in conjunctival sac	0.878	0.121
T88.3 Malignant hyperthermia due to anaesthesis	0.879	0.121
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.879	0.121
T02.5 Fractures involving multiple regions of both lower limbs	0.879	0.121
T70 Effects of air pressure and water pressure	0.879	0.121
T25 Burn and corrosion of ankle and foot	0.879	0.121
S27.1 Traumatic haemothorax	0.880	0.120
T51 Toxic effect of alcohol	0.880	0.120
T31 Burns classified according to extent of body surface involved	0.880	0.120
T82.4 Mechanical complication of vascular dialysis catheter	0.880	0.120
T88.1 Other complications following immunisation, not elsewhere classified	0.880	0.120
T88.0 Infection following immunisation	0.880	0.120
T68 Hypothermia	0.880	0.120
T60 Toxic effect of pesticides	0.881	0.119
T57 Toxic effect of other inorganic substances	0.881	0.119
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.881	0.119
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.881	0.119
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.881	0.119
S27.2 Traumatic heamopneumothorax	0.881	0.119
S50-S59 Injuries to the elbow and forearm	0.882	0.118
S62.4 Multiple fractures of metacarpal bones	0.882	0.118
T02.2 Fractures involving multiple regions of one upper limb	0.882	0.117
S62.0 Fracture of navicular [scaphoid] bone of hand	0.882	0.118
T19.1 Foreign body in bladder	0.882	0.117
T61 Toxic effect of noxious substances eaten as seafood	0.883	0.117
T52 Toxic effect of organic solvents	0.883	0.117
T15.9 Foreign body on external eye, unspecified	0.883	0.116
T56 Toxic effect of metals	0.883	0.117
T03.9 Multiple dislocations, sprains and strains, unspecified	0.883	0.116
T03.8 Dislocations, sprains and strains involving other combinations of body regions	0.883	0.116
T03.4 Dislocations, sprains and strains involving multiple regions of upper limb(s) with lower limb(s)	0.883	0.116
T03.3 Dislocations, sprains and strains involving multiple regions of lower limb(s)	0.883	0.116
T03.2 Dislocations, sprains and strains involving multiple regions of upper limb(s)	0.883	0.116
T03.1 Dislocations, sprains and strains involving thorax with lower back and pelvis	0.883	0.116
T03.0 Dislocations, sprains and strains involving head with neck	0.883	0.116
T04.9 Multiple crushing injuries, unspecified	0.883	0.116
T04.8 Crushing injuries involving other combinations of body regions	0.883	0.116
T04.7 Crushing injuries of thorax with abdomen, lower back and pelvis with limb(s)	0.883	0.116
T04.4 Crushing injuries involving multiple regions of upper limb(s) with lower limb(s)	0.883	0.116
T04.3 Crushing injuries involving multiple regions of lower limb(s)	0.883	0.116
T04.2 Crushing injuries involving multiple regions of upper limb(s)	0.883	0.116
T04.1 Crushing injuries involving thorax with abdomen, lower back and pelvis	0.883	0.116
T04.0 Crushing injuries involving head with neck	0.883	0.116
T05.9 Multiple traumatic amputations, unspecified	0.883	0.116
T05.8 Traumatic amputations involving other combinations of body regions	0.883	0.116
T05.6 Traumatic amputation of upper and lower limbs, any combination [any level]	0.883	0.116
T05.5 Traumatic amputation of both legs [any level]	0.883	0.116
T05.4 Traumatic amputation of one foot and other leg [any level, except foot]	0.883	0.116
T05.3 Traumatic amputation of both feet	0.883	0.116
T05.2 Traumatic amputation of both arms [any level]	0.883	0.116
T05.1 Traumatic amputation of one hand and other arm [any level, except hand]	0.883	0.116
T05.0 Traumatic amputation of both hands	0.883	0.116
T66 Unspecified effects of radiation	0.883	0.116
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.883	0.116
S68.8 Traumatic amputation of other parts of wrist and hand	0.883	0.116
S68.4 Traumatic amputation of hand at wrist level	0.883	0.116
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.883	0.116
T55 Toxic effect of soaps and detergents	0.884	0.116
S91.1 Open wound of toe(s) without damage to nail	0.884	0.116
T62 Toxic effect of other noxious substances eaten as food	0.884	0.116
S69.8 Other specified injuries of wrist and hand	0.885	0.115
S62.61 Fracture of other finger (open)	0.885	0.115
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.886	0.114
T88.5 Other complications of anaesthesia	0.886	0.114
T06.8 Other specified injuries involving multiple body regions	0.886	0.113
T06.5 Injuries of intrathoracic organs with intra-abdominal and pelvic organs	0.886	0.113
T06.3 Injuries of blood vessels involving multiple body regions	0.886	0.113
T06.2 Injuries of nerves involving multiple body regions	0.886	0.113
T06.1 Injuries of nerves and spinal cord involving other multiple body regions	0.886	0.113
T06.0 Injuries of brain and cranial nerves with injuries of nerves and spinal cord at neck level	0.886	0.113
S26 Injury of heart	0.887	0.113
T17.2 Foreign body in pharynx	0.887	0.113
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.887	0.113
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.887	0.112
S25 Injury of blood vessels of thorax	0.887	0.112
S99.9 Unspecified injury of ankle and foot	0.888	0.112
S27.3 Other injuries of lung	0.888	0.112
S94.9 Injury of unspecified nerve at ankle and foot level	0.888	0.112
S94.8 Injury of other nerves at ankle and foot level	0.888	0.112
S94.7 Injury of multiple nerves at ankle and foot level	0.888	0.112
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.888	0.112
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.888	0.112
S94.1 Injury of medial plantar nerve	0.888	0.112
S94.0 Injury of lateral plantar nerve	0.888	0.112
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.888	0.112
S95.8 Injury of other blood vessels at ankle and foot level	0.888	0.112
S95.7 Injury of multiple blood vessels at ankle and foot level	0.888	0.112
S95.2 Injury of dorsal vein of foot	0.888	0.112
S95.1 Injury of plantar artery of foot	0.888	0.112
S95.0 Injury of dorsal artery of foot	0.888	0.112
S92.31 Fracture of metatarsal bone (open)	0.888	0.112
T58 Toxic effect of carbon monoxide	0.888	0.112
S99.7 Multiple injuries of ankle and foot	0.888	0.112
S62.20 Fracture of first metacarpal bone (closed)	0.888	0.112
S62.60 Fracture of other finger (closed)	0.888	0.112
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.888	0.111
S69.9 Unspecified injury of wrist and hand	0.889	0.111
T80.2 Infections following infusion, transfusion and therapeutic injection	0.889	0.111
T79 Certain early complications of trauma, not elsewhere classified	0.889	0.111
S99.8 Other specified injuries of ankle and foot	0.889	0.111
T59.9 Gases, fumes and vapours, unspecified	0.890	0.110
T06.4 Injuries of muscles and tendons involving multiple body regions	0.890	0.109
S20 Superficial injury of thorax	0.890	0.110
T17.3 Foreign body in larynx	0.890	0.109
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.891	0.108
S92.0 Fracture of calcaneus	0.891	0.108
T74 Maltreatment syndromes	0.892	0.108
T73 Effects of other deprivation	0.892	0.108
T69 Other effects of reduced temperature	0.892	0.108
T67 Effects of heat and light	0.892	0.108
S65.0 Injury of ulnar artery at wrist and hand level	0.892	0.108
S65.4 Injury of blood vessel(s) of thumb	0.892	0.108
T82.0 Mechanical complication of heart valve prosthesis	0.892	0.108
S93.0 Dislocation of ankle joint	0.892	0.107
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.893	0.107
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.893	0.107
T02.80 Fractures involving other combinations of body regions (closed)	0.893	0.106
S64.4 Injury of digital nerve of other finger	0.894	0.106
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.894	0.106
S93.3 Dislocation of other and unspecified parts of foot	0.894	0.105
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.895	0.105
S65.8 Injury of other blood vessels at wrist and hand level	0.895	0.105
S65.7 Injury of multiple blood vessels at wrist and hand level	0.895	0.105
S65.3 Injury of deep palmar arch	0.895	0.105
S65.2 Injury of superficial palmar arch	0.895	0.105
T65 Toxic effect of other and unspecified substances	0.895	0.105
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.895	0.105
S24 Injury of nerves and spinal cord at thorax level	0.895	0.104
T17.4 Foreign body in trachea	0.895	0.104
T17.1 Foreign body in nostril	0.895	0.104
T17.0 Foreign body in nasal sinus	0.895	0.104
S92.50 Fracture of other toe (closed)	0.897	0.103
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.897	0.103
S97.0 Crushing injury of ankle	0.898	0.102
T25.2 Burn of second degree of ankle and foot	0.898	0.102
S93.4 Sprain and strain of ankle	0.898	0.102
S93.5 Sprain and strain of toe(s)	0.898	0.102
S97.1 Crushing injury of toe(s)	0.898	0.102
S27.8 Injury of other specified intrathoracic organs	0.898	0.101
T29.3 Burns of multiple regions, at least one burn of third degree mentioned	0.898	0.101
S27.9 Injury of unspecified intrathoracic organ	0.899	0.101
S27.7 Multiple injuries of intrathoracic organs	0.899	0.101
S27.6 Injury of pleura	0.899	0.101
S27.5 Injury of thoracic trachea	0.899	0.101
S27.4 Injury of bronchus	0.899	0.101
S62.21 Fracture of first metacarpal bone (open)	0.899	0.101
S65.5 Injury of blood vessel(s) of other finger	0.899	0.101
S92.20 Fracture of other tarsal bone(s) (closed)	0.899	0.101
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.899	0.101

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations