TreeWAS – Variant ID: rs616597

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z45.8 Adjustment and management of other implanted devices	0.000	0.927	0.073
K51.9 Ulcerative colitis, unspecified	0.065	0.935	0.000
K51 Ulcerative colitis	0.063	0.937	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.060	0.940	0.000
K51.8 Other ulcerative colitis	0.058	0.941	0.000
K51.2 Ulcerative (chronic) proctitis	0.054	0.946	0.000
K51.4 Pseudopolyposis of colon	0.045	0.954	0.000
K51.5 Mucosal proctocolitis	0.043	0.957	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.041	0.959	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.040	0.960	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.022	0.978	0.000
T42.4 Benzodiazepines	0.021	0.979	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.019	0.981	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.018	0.982	0.000
T42.0 Hydantoin derivatives	0.016	0.984	0.000
T42.1 Iminostilbenes	0.016	0.984	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.015	0.985	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.014	0.985	0.000
T42.3 Barbiturates	0.014	0.986	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.013	0.986	0.000
T42.2 Succinimides and oxazolidinediones	0.013	0.986	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.013	0.987	0.000
T50.4 Drugs affecting uric acid metabolism	0.013	0.987	0.000
T50.7 Analeptics and opioid receptor antagonists	0.013	0.987	0.000
T50.5 Appetite depressants	0.013	0.987	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.013	0.987	0.000
T50.1 Loop [high-ceiling] diuretics	0.013	0.987	0.000
T50.0 Mineralocorticoids and their antagonists	0.013	0.987	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.013	0.987	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.000	0.987	0.013
T36 Poisoning by systemic antibiotics	0.012	0.988	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.012	0.988	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.012	0.988	0.000
T50.8 Diagnostic agents	0.012	0.988	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.012	0.988	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.012	0.988	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.012	0.988	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.011	0.989	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.011	0.989	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.011	0.989	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.011	0.989	0.000
H57 Other disorders of eye and adnexa	0.000	0.989	0.011
H57.1 Ocular pain	0.000	0.989	0.011
T36.0 Penicillins	0.011	0.989	0.000
H57.8 Other specified disorders of eye and adnexa	0.000	0.989	0.011
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.010	0.990	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.010	0.990	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.010	0.990	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.010	0.990	0.000
T40.2 Other opioids	0.010	0.990	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.010	0.990	0.000
T48.5 Anti-common-cold drugs	0.009	0.990	0.000
T40.5 Cocaine	0.009	0.991	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.009	0.991	0.000
C50.2 Upper-inner quadrant of breast	0.009	0.991	0.000
T36.4 Tetracyclines	0.009	0.991	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.009	0.991	0.000
T40.3 Methadone	0.009	0.991	0.000
T36.9 Systemic antibiotic, unspecified	0.009	0.991	0.000
T36.7 Antifungal antibiotics, systemically used	0.009	0.991	0.000
T36.6 Rifamycins	0.009	0.991	0.000
T36.5 Aminoglycosides	0.009	0.991	0.000
T36.2 Chloramphenicol group	0.009	0.991	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.009	0.991	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.009	0.991	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.009	0.991	0.000
T36.8 Other systemic antibiotics	0.009	0.991	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.009	0.991	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.009	0.991	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.009	0.991	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.009	0.991	0.000
T36.3 Macrolides	0.009	0.991	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.009	0.991	0.000
T48.4 Expectorants	0.009	0.991	0.000
T48.3 Antitussives	0.009	0.991	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.009	0.991	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.009	0.991	0.000
T48.0 Oxytocic drugs	0.009	0.991	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.008	0.991	0.000
T40.8 Lysergide [LSD]	0.008	0.991	0.000
T40.7 Cannabis (derivatives)	0.008	0.991	0.000
T40.0 Opium	0.008	0.991	0.000
T45.0 Antiallergic and antiemetic drugs	0.008	0.991	0.000
T49.9 Topical agent, unspecified	0.008	0.991	0.000
T49.8 Other topical agents	0.008	0.991	0.000
T49.7 Dental drugs, topically applied	0.008	0.991	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.008	0.991	0.000
T49.5 Ophthalmological drugs and preparations	0.008	0.991	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.008	0.991	0.000
T49.3 Emollients, demulcents and protectants	0.008	0.991	0.000
T49.2 Local astringents and local detergents	0.008	0.991	0.000
T49.1 Antipruritics	0.008	0.991	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.008	0.992	0.000
T37.5 Antiviral drugs	0.008	0.992	0.000
T37.4 Anthelminthics	0.008	0.992	0.000
T37.3 Other antiprotozoal drugs	0.008	0.992	0.000
T37.1 Antimycobacterial drugs	0.008	0.992	0.000
T37.0 Sulphonamides	0.008	0.992	0.000
T40.1 Heroin	0.008	0.992	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.008	0.992	0.000
R00.8 Other and unspecified abnormalities of heart beat	0.008	0.992	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.008	0.992	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.008	0.992	0.000
T39.4 Antirheumatics, not elsewhere classified	0.008	0.992	0.000
T39.2 Pyrazolone derivatives	0.008	0.992	0.000
T41.5 Therapeutic gases	0.008	0.992	0.000
T41.4 Anaesthetic, unspecified	0.008	0.992	0.000
T41.3 Local anaesthetics	0.008	0.992	0.000
T41.2 Other and unspecified general anaesthetics	0.008	0.992	0.000
T41.1 Intravenous anaesthetics	0.008	0.992	0.000
T41.0 Inhaled anaesthetics	0.008	0.992	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.008	0.992	0.000
T40.6 Other and unspecified narcotics	0.008	0.992	0.000
T43.9 Psychotropic drug, unspecified	0.008	0.992	0.000
T38.5 Other oestrogens and progestogens	0.008	0.992	0.000
T43.2 Other and unspecified antidepressants	0.008	0.992	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.007	0.992	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.007	0.992	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.007	0.993	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.007	0.993	0.000
T47.7 Emetics	0.007	0.993	0.000
T47.5 Digestants	0.007	0.993	0.000
T47.3 Saline and osmotic laxatives	0.007	0.993	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.007	0.993	0.000
T45.8 Other primarily systemic and haematological agents	0.007	0.993	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.007	0.993	0.000
T45.6 Fibrinolysis-affecting drugs	0.007	0.993	0.000
T45.3 Enzymes, not elsewhere classified	0.007	0.993	0.000
T38.9 Other and unspecified hormone antagonists	0.007	0.993	0.000
T38.7 Androgens and anabolic congeners	0.007	0.993	0.000
T38.4 Oral contraceptives	0.007	0.993	0.000
T38.2 Antithyroid drugs	0.007	0.993	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.007	0.993	0.000
T45.2 Vitamins, not elsewhere classified	0.007	0.993	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.007	0.993	0.000
T47.2 Stimulant laxatives	0.007	0.993	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.000	0.993	0.007
T39.0 Salicylates	0.007	0.993	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.007	0.993	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.007	0.993	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.007	0.993	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.007	0.993	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.007	0.993	0.000
T44.0 Anticholinesterase agents	0.007	0.993	0.000
T45.4 Iron and its compounds	0.007	0.993	0.000
T47.6 Antidiarrhoeal drugs	0.007	0.993	0.000
T38.0 Glucocorticoids and synthetic analogues	0.007	0.993	0.000
T47.4 Other laxatives	0.007	0.993	0.000
T47.0 Histamine H(2)-receptor antagonists	0.006	0.993	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.006	0.993	0.000
T38.1 Thyroid hormones and substitutes	0.006	0.993	0.000
D86.0 Sarcoidosis of lung	0.007	0.993	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.006	0.994	0.000
H57.0 Anomalies of pupillary function	0.000	0.994	0.006
R47.1 Dysarthria and anarthria	0.000	0.994	0.006
D86.9 Sarcoidosis, unspecified	0.006	0.994	0.000
T43.6 Psychostimulants with abuse potential	0.006	0.994	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.006	0.994	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.006	0.994	0.000
T51.0 Ethanol	0.006	0.994	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.994	0.006
T45.5 Anticoagulants	0.006	0.994	0.000
T51.9 Alcohol, unspecified	0.006	0.994	0.000
T40.4 Other synthetic narcotics	0.006	0.994	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.006	0.994	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.006	0.994	0.000
M95.0 Acquired deformity of nose	0.006	0.994	0.000
O46.9 Antepartum haemorrhage, unspecified	0.006	0.994	0.000
D86 Sarcoidosis	0.006	0.994	0.000
Q61.0 Congenital single renal cyst	0.000	0.995	0.005
T51 Toxic effect of alcohol	0.005	0.995	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
Z37.2 Twins, both liveborn	0.005	0.995	0.000
M50.3 Other cervical disk degeneration	0.000	0.995	0.005
O30.0 Twin pregnancy	0.005	0.995	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.005	0.995	0.000
T46.1 Calcium-channel blockers	0.005	0.995	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.004	0.995	0.000
T46.7 Peripheral vasodilators	0.004	0.995	0.000
L73.9 Follicular disorder, unspecified	0.000	0.995	0.005
R47.8 Other and unspecified speech disturbances	0.000	0.995	0.005
K50-K52 Noninfective enteritis and colitis	0.005	0.995	0.000
D86.8 Sarcoidosis of other and combined sites	0.004	0.995	0.000
L30.8 Other specified dermatitis	0.000	0.996	0.004
S52.60 Fracture of lower end of both ulna and radius (closed)	0.000	0.996	0.004
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
T39.1 4-Aminophenol derivatives	0.004	0.996	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.996	0.004
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.996	0.000
R47 Speech disturbances, not elsewhere classified	0.000	0.996	0.004
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.996	0.004
T51.8 Other alcohols	0.004	0.996	0.000
T51.3 Fusel oil	0.004	0.996	0.000
T51.2 2-Propanol	0.004	0.996	0.000
T51.1 Methanol	0.004	0.996	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
N93.8 Other specified abnormal uterine and vaginal bleeding	0.000	0.996	0.004
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.004	0.996	0.000
D86.3 Sarcoidosis of skin	0.004	0.996	0.000
M23.8 Other internal derangements of knee	0.000	0.996	0.004
L81.4 Other melanin hyperpigmentation	0.000	0.996	0.004
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
N42.2 Atrophy of prostate	0.000	0.996	0.004
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.004	0.996	0.000
N42 Other disorders of prostate	0.000	0.996	0.004
N42.1 Congestion and haemorrhage of prostate	0.000	0.996	0.004
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.004	0.996	0.000
N42.8 Other specified disorders of prostate	0.000	0.996	0.004
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.996	0.004
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.004	0.996	0.000
N42.0 Calculus of prostate	0.000	0.996	0.004
D86.1 Sarcoidosis of lymph nodes	0.003	0.996	0.000
M95.3 Acquired deformity of neck	0.003	0.996	0.000
M95.4 Acquired deformity of chest and rib	0.003	0.997	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.997	0.003
H53.9 Visual disturbance, unspecified	0.000	0.997	0.003
T46.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
I84.5 External haemorrhoids without complication	0.003	0.997	0.000
O30 Multiple gestation	0.003	0.997	0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.003	0.997	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.003	0.997	0.000
M95.5 Acquired deformity of pelvis	0.003	0.997	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.997	0.003
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.997	0.003
M95.1 Cauliflower ear	0.003	0.997	0.000
D80-D89 Certain disorders involving the immune mechanism	0.003	0.997	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.997	0.003
N21.0 Calculus in bladder	0.003	0.997	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.997	0.003
O46 Antepartum haemorrhage, not elsewhere classified	0.003	0.997	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.997	0.003
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.003
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.997	0.003
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.997	0.003
M96.0 Pseudarthrosis after fusion or arthrodesis	0.003	0.997	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.003	0.997	0.000
M95.2 Other acquired deformity of head	0.003	0.997	0.000
I67.2 Cerebral atherosclerosis	0.000	0.997	0.003
N42.3 Dysplasia of prostate	0.000	0.997	0.003
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.997	0.003
O30.1 Triplet pregnancy	0.003	0.997	0.000
Z45 Adjustment and management of implanted device	0.000	0.997	0.003
L85.8 Other specified epidermal thickening	0.000	0.997	0.003
K38.8 Other specified diseases of appendix	0.000	0.997	0.003
N32.9 Bladder disorder, unspecified	0.000	0.997	0.003
O30.9 Multiple gestation, unspecified	0.002	0.997	0.000
O30.8 Other multiple gestation	0.002	0.997	0.000
O30.2 Quadruplet pregnancy	0.002	0.997	0.000
L73.2 Hidradenitis suppurativa	0.002	0.997	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.003	0.997	0.000
D83 Common variable immunodeficiency	0.003	0.997	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.997	0.003
S64.2 Injury of radial nerve at wrist and hand level	0.003	0.997	0.000
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.002	0.997	0.000
D89.1 Cryoglobulinaemia	0.002	0.997	0.000
M24.1 Other articular cartilage disorders	0.000	0.997	0.003
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.997	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.002	0.997	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.002	0.997	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.998	0.002
D81 Combined immunodeficiencies	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
M19.0 Primary arthrosis of other joints	0.000	0.998	0.002
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.002	0.998	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.002	0.998	0.000
D23.0 Skin of lip	0.000	0.998	0.002
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
D89.3 Immune reconstitution syndrome	0.002	0.998	0.000
R47.0 Dysphasia and aphasia	0.000	0.998	0.002
J36 Peritonsillar abscess	0.002	0.998	0.000
L30 Other dermatitis	0.000	0.998	0.002
L30.3 Infective dermatitis	0.000	0.998	0.002
S64 Injury of nerves at wrist and hand level	0.002	0.998	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.998	0.002
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
D84 Other immunodeficiencies	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
L81 Other disorders of pigmentation	0.000	0.998	0.002
S64.4 Injury of digital nerve of other finger	0.002	0.998	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.998	0.002
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
S52.6 Fracture of lower end of both ulna and radius	0.000	0.998	0.002
Z45.9 Adjustment and management of unspecified implanted device	0.000	0.998	0.002
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
R50.8 Other specified fever	0.000	0.998	0.002
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.002	0.998	0.000
D23.5 Skin of trunk	0.000	0.998	0.002
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.998	0.002
M24.18 Other articular cartilage disorders (Other)	0.000	0.998	0.002
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.998	0.002
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.998	0.002
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
M24.0 Loose body in joint	0.000	0.998	0.002
S63.6 Sprain and strain of finger(s)	0.002	0.998	0.000
M24.07 Loose body in joint (Ankle and foot)	0.000	0.998	0.002
M24.14 Other articular cartilage disorders (Hand)	0.000	0.998	0.002
L81.9 Disorder of pigmentation, unspecified	0.000	0.998	0.002
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.002	0.998	0.000
M96.4 Postsurgical lordosis	0.002	0.998	0.000
M96.3 Postlaminectomy kyphosis	0.002	0.998	0.000
M96.2 Postradiation kyphosis	0.002	0.998	0.000
S70.1 Contusion of thigh	0.000	0.998	0.002
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.998	0.002
M96.8 Other postprocedural musculoskeletal disorders	0.002	0.998	0.000
S64.3 Injury of digital nerve of thumb	0.002	0.998	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.998	0.002
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.002	0.998	0.000
M24.01 Loose body in joint (Shoulder region)	0.000	0.998	0.002
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.002	0.998	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.998	0.002
D23.6 Skin of upper limb, including shoulder	0.000	0.998	0.002
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
L30.9 Dermatitis, unspecified	0.000	0.998	0.002
O34.1 Maternal care for tumour of corpus uteri	0.002	0.998	0.000
M24.03 Loose body in joint (Forearm)	0.000	0.998	0.002
J15.1 Pneumonia due to Pseudomonas	0.002	0.998	0.000
S64.1 Injury of median nerve at wrist and hand level	0.002	0.998	0.000
Z45.3 Adjustment and management of implanted hearing device	0.000	0.998	0.002
M99 Biomechanical lesions, not elsewhere classified	0.002	0.998	0.000
S70 Superficial injury of hip and thigh	0.000	0.998	0.002
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.002	0.998	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.002	0.998	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.998	0.002
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
N39.8 Other specified disorders of urinary system	0.002	0.998	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.002	0.998	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.002	0.998	0.000
J32.0 Chronic maxillary sinusitis	0.002	0.998	0.000
L30.5 Pityriasis alba	0.000	0.998	0.002
L30.2 Cutaneous autosensitisation	0.000	0.998	0.002
L81.2 Freckles	0.000	0.998	0.002
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.002	0.998	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.998	0.002
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.000	0.998	0.002
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
L30.0 Nummular dermatitis	0.000	0.998	0.002
S64.9 Injury of unspecified nerve at wrist and hand level	0.002	0.998	0.000
S64.8 Injury of other nerves at wrist and hand level	0.002	0.998	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.998	0.002
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.002	0.998	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.002	0.998	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.002	0.998	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.998	0.002
F33.9 Recurrent depressive disorder, unspecified	0.000	0.998	0.002
L81.0 Postinflammatory hyperpigmentation	0.000	0.998	0.002
O46.8 Other antepartum haemorrhage	0.002	0.998	0.000
M19.08 Primary arthrosis of other joints (Other)	0.000	0.998	0.002
D46.7 Other myelodysplastic syndromes	0.000	0.998	0.002
L81.6 Other disorders of diminished melanin formation	0.000	0.998	0.002
L81.5 Leukoderma, not elsewhere classified	0.000	0.998	0.002
L81.3 Cafe au lait spots	0.000	0.998	0.002
L81.1 Chloasma	0.000	0.998	0.002
M96.5 Postradiation scoliosis	0.002	0.998	0.000
O44.1 Placenta praevia with haemorrhage	0.002	0.998	0.000
I11 Hypertensive heart disease	0.000	0.998	0.002
M24.04 Loose body in joint (Hand)	0.000	0.998	0.002
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
L81.7 Pigmented purpuric dermatosis	0.000	0.998	0.002
S70.7 Multiple superficial injuries of hip and thigh	0.000	0.998	0.002
S66 Injury of muscle and tendon at wrist and hand level	0.002	0.998	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.998	0.002
M24.23 Disorder of ligament (Forearm)	0.000	0.998	0.002
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.002	0.998	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.002	0.998	0.000
S67 Crushing injury of wrist and hand	0.002	0.998	0.000
M24.02 Loose body in joint (Upper arm)	0.000	0.998	0.002
D84.1 Defects in the complement system	0.002	0.998	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.002	0.998	0.000
L30.1 Dyshidrosis [pompholyx]	0.000	0.998	0.002
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.002	0.998	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.000	0.998	0.002
H55-H59 Other disorders of eye and adnexa	0.000	0.998	0.002
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.002	0.998	0.000
M24.06 Loose body in joint-Lower leg	0.000	0.998	0.002
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
L81.8 Other specified disorders of pigmentation	0.000	0.998	0.002
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.002	0.998	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.998	0.002
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.002	0.998	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.002	0.998	0.000
V28.9 Unspecified motorcycle rider injured in traffic accident	0.000	0.998	0.002
M24.09 Loose body in joint (Site unspecified)	0.000	0.998	0.002
M24.08 Loose body in joint (Other)	0.000	0.998	0.002
M24.00 Loose body in joint (Multiple sites)	0.000	0.998	0.002
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.002	0.998	0.000
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.002	0.998	0.000
S72.40 Fracture of lower end of femur (closed)	0.000	0.998	0.002
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.002	0.998	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.002	0.998	0.000
O40 Polyhydramnios	0.002	0.998	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.998	0.002
S72.41 Fracture of lower end of femur (open)	0.000	0.998	0.002
M82.1 Osteoporosis in endocrine disorders	0.002	0.998	0.000
O33.9 Maternal care for disproportion, unspecified	0.002	0.998	0.000
H33.2 Serous retinal detachment	0.000	0.998	0.002
L30.4 Erythema intertrigo	0.000	0.998	0.002
M99.5 Intervertebral disk stenosis of neural canal	0.002	0.998	0.000
O44 Placenta praevia	0.002	0.998	0.000
O42.9 Premature rupture of membranes, unspecified	0.002	0.998	0.000
O41 Other disorders of amniotic fluid and membranes	0.002	0.998	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.002	0.998	0.000
D46 Myelodysplastic syndromes	0.000	0.998	0.002
S36.00 Injury of spleen (without open wound into cavity)	0.002	0.998	0.000
D46.2 Refractory anaemia with excess of blasts	0.000	0.998	0.002
J15.8 Other bacterial pneumonia	0.002	0.998	0.000
J15.4 Pneumonia due to other streptococci	0.002	0.998	0.000
M99.9 Biomechanical lesion, unspecified	0.001	0.998	0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina	0.001	0.998	0.000
M99.4 Connective tissue stenosis of neural canal	0.001	0.998	0.000
M99.3 Osseous stenosis of neural canal	0.001	0.998	0.000
M99.2 Subluxation stenosis of neural canal	0.001	0.998	0.000
M99.1 Subluxation complex (vertebral)	0.001	0.998	0.000
M99.0 Segmental and somatic dysfunction	0.001	0.998	0.000
O33 Maternal care for known or suspected disproportion	0.002	0.998	0.000
C53.9 Cervix uteri, unspecified	0.002	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.002	0.998	0.000
L73.8 Other specified follicular disorders	0.000	0.998	0.001
O34.3 Maternal care for cervical incompetence	0.002	0.998	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.002	0.998	0.000
Z45.1 Adjustment and management of infusion pump	0.000	0.998	0.002
L73 Other follicular disorders	0.000	0.998	0.001
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
M80.8 Other osteoporosis with pathological fracture	0.002	0.998	0.000
R68.0 Hypothermia, not associated with low environmental temperature	0.000	0.998	0.002
S36.1 Injury of liver or gallbladder	0.002	0.998	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.000	0.998	0.002
D46.4 Refractory anaemia, unspecified	0.000	0.998	0.002
D75.1 Secondary polycythaemia	0.000	0.998	0.002
J15.3 Pneumonia due to streptococcus, group B	0.002	0.998	0.000
M99.8 Other biomechanical lesions	0.001	0.998	0.000
O34.6 Maternal care for abnormality of vagina	0.002	0.998	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.002	0.998	0.000
R68.8 Other specified general symptoms and signs	0.000	0.998	0.002
O31 Complications specific to multiple gestation	0.002	0.998	0.000
D07.1 Vulva	0.000	0.998	0.002
D16.5 Lower jaw bone	0.000	0.998	0.002
K25.7 Chronic without haemorrhage or perforation	0.000	0.998	0.002
K42.0 Umbilical hernia with obstruction, without gangrene	0.002	0.998	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.002	0.998	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.002	0.998	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
M24.2 Disorder of ligament	0.000	0.998	0.002
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.001	0.998	0.000
S72.4 Fracture of lower end of femur	0.000	0.998	0.002
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.998	0.001
M80.88 Other osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.001	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.001	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.001	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.001	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.001	0.998	0.000
O41.0 Oligohydramnios	0.002	0.998	0.000
S36.0 Injury of spleen	0.002	0.998	0.000
Z39.0 Care and examination immediately after delivery	0.002	0.998	0.000
M80 Osteoporosis with pathological fracture	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.001	0.998	0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina	0.001	0.998	0.000
O34.4 Maternal care for other abnormalities of cervix	0.001	0.998	0.000
S70.0 Contusion of hip	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations