TreeWAS – Variant ID: rs62533402

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S92.00 Fracture of calcaneus (closed)	0.000	0.955	0.045
S92.0 Fracture of calcaneus	0.000	0.972	0.028
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.980	0.020
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.980	0.020
S92.01 Fracture of calcaneus (open)	0.000	0.980	0.020
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.981	0.019
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.983	0.017
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.984	0.016
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.984	0.016
S92 Fracture of foot, except ankle	0.000	0.985	0.015
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.986	0.014
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.986	0.014
S66.8 Injury of other muscles and tendons at wrist and hand level	0.000	0.986	0.014
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.000	0.986	0.014
O63.9 Long labour, unspecified	0.014	0.986	0.000
S92.1 Fracture of talus	0.000	0.988	0.012
S92.7 Multiple fractures of foot	0.000	0.988	0.012
S92.9 Fracture of foot, unspecified	0.000	0.989	0.011
S92.4 Fracture of great toe	0.000	0.989	0.011
S92.3 Fracture of metatarsal bone	0.000	0.989	0.011
S92.2 Fracture of other tarsal bone(s)	0.000	0.989	0.011
S92.10 Fracture of talus (closed)	0.000	0.990	0.010
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.990	0.010
S92.5 Fracture of other toe	0.000	0.990	0.010
S92.70 Multiple fractures of foot (closed)	0.000	0.990	0.009
S92.11 Fracture of talus (open)	0.000	0.991	0.009
S92.71 Multiple fractures of foot (open)	0.000	0.991	0.009
S92.91 Fracture of foot, unspecified (open)	0.000	0.992	0.008
S92.90 Fracture of foot, unspecified (closed)	0.000	0.992	0.008
S92.31 Fracture of metatarsal bone (open)	0.000	0.992	0.008
S92.40 Fracture of great toe (closed)	0.000	0.992	0.008
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.992	0.008
S92.41 Fracture of great toe (open)	0.000	0.992	0.008
S92.30 Fracture of metatarsal bone (closed)	0.000	0.992	0.008
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.992	0.008
S92.51 Fracture of other toe (open)	0.000	0.993	0.007
S92.50 Fracture of other toe (closed)	0.000	0.994	0.006
I42.0 Dilated cardiomyopathy	0.006	0.994	0.000
L71.9 Rosacea, unspecified	0.005	0.995	0.000
K12.1 Other forms of stomatitis	0.000	0.995	0.005
C45.0 Mesothelioma of pleura	0.005	0.995	0.000
I20.8 Other forms of angina pectoris	0.000	0.995	0.005
C45.9 Mesothelioma, unspecified	0.004	0.996	0.000
I42.9 Cardiomyopathy, unspecified	0.004	0.996	0.000
M54.16 Radiculopathy (Lumbar region)	0.004	0.996	0.000
C45 Mesothelioma	0.004	0.996	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.996	0.004
I42 Cardiomyopathy	0.004	0.996	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.996	0.004
S90-S99 Injuries to the ankle and foot	0.000	0.996	0.004
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.996	0.004
M35.3 Polymyalgia rheumatica	0.000	0.996	0.004
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.997	0.003
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M54.1 Radiculopathy	0.003	0.997	0.000
M54.12 Radiculopathy (Cervical region)	0.003	0.997	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.997	0.003
I42.7 Cardiomyopathy due to drugs and other external agents	0.003	0.997	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.997	0.003
I42.6 Alcoholic cardiomyopathy	0.003	0.997	0.000
S93.1 Dislocation of toe(s)	0.000	0.997	0.003
C45.2 Mesothelioma of pericardium	0.003	0.997	0.000
C45.1 Mesothelioma of peritoneum	0.003	0.997	0.000
C45.7 Mesothelioma of other sites	0.003	0.997	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.997	0.003
M06.9 Rheumatoid arthritis, unspecified	0.000	0.997	0.003
I42.5 Other restrictive cardiomyopathy	0.003	0.997	0.000
I42.4 Endocardial fibroelastosis	0.003	0.997	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.003	0.997	0.000
Z94.0 Kidney transplant status	0.000	0.997	0.003
L71 Rosacea	0.003	0.997	0.000
S98 Traumatic amputation of ankle and foot	0.000	0.997	0.003
S95 Injury of blood vessels at ankle and foot level	0.000	0.997	0.003
S94 Injury of nerves at ankle and foot level	0.000	0.997	0.003
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.003	0.997	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.997	0.003
S97 Crushing injury of ankle and foot	0.000	0.997	0.003
L71.8 Other rosacea	0.003	0.997	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.003	0.997	0.000
M54.19 Radiculopathy (Site unspecified)	0.003	0.997	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.003	0.997	0.000
M54.14 Radiculopathy (Thoracic region)	0.003	0.997	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.003	0.997	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.003	0.997	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.003	0.997	0.000
S99 Other and unspecified injuries of ankle and foot	0.000	0.997	0.003
I42.8 Other cardiomyopathies	0.003	0.997	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.997	0.003
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.003	0.997	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.997	0.002
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.997	0.002
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.997	0.002
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.997	0.002
M43.19 Spondylolisthesis (Site unspecified)	0.003	0.997	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.997	0.002
I63.8 Other cerebral infarction	0.000	0.997	0.002
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.998	0.002
I31.3 Pericardial effusion (noninflammatory)	0.002	0.998	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.000	0.998	0.002
S93.4 Sprain and strain of ankle	0.000	0.998	0.002
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.998	0.002
S93.5 Sprain and strain of toe(s)	0.000	0.998	0.002
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.998	0.002
S90 Superficial injury of ankle and foot	0.000	0.998	0.002
H53.4 Visual field defects	0.000	0.998	0.002
L71.0 Perioral dermatitis	0.002	0.998	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
L71.1 Rhinophyma	0.002	0.998	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.998	0.002
S94.8 Injury of other nerves at ankle and foot level	0.000	0.998	0.002
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.998	0.002
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.998	0.002
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.998	0.002
S94.1 Injury of medial plantar nerve	0.000	0.998	0.002
S94.0 Injury of lateral plantar nerve	0.000	0.998	0.002
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.998	0.002
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.998	0.002
S95.7 Injury of multiple blood vessels at ankle and foot level	0.000	0.998	0.002
S95.2 Injury of dorsal vein of foot	0.000	0.998	0.002
S95.1 Injury of plantar artery of foot	0.000	0.998	0.002
S95.0 Injury of dorsal artery of foot	0.000	0.998	0.002
S98.4 Traumatic amputation of foot, level unspecified	0.000	0.998	0.002
S98.3 Traumatic amputation of other parts of foot	0.000	0.998	0.002
S98.2 Traumatic amputation of two or more toes	0.000	0.998	0.002
S98.1 Traumatic amputation of one toe	0.000	0.998	0.002
S98.0 Traumatic amputation of foot at ankle level	0.000	0.998	0.002
S97.1 Crushing injury of toe(s)	0.000	0.998	0.002
S97.0 Crushing injury of ankle	0.000	0.998	0.002
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
N28.9 Disorder of kidney and ureter, unspecified	0.002	0.998	0.000
S91 Open wound of ankle and foot	0.000	0.998	0.002
Q50.4 Embryonic cyst of Fallopian tube	0.002	0.998	0.000
J38.7 Other diseases of larynx	0.000	0.998	0.002
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.998	0.002
T79.7 Traumatic subcutaneous emphysema	0.002	0.998	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.998	0.002
E14.9 Without complications	0.000	0.998	0.002
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.002
F02.3 Dementia in Parkinson's disease	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.000	0.998	0.002
S99.7 Multiple injuries of ankle and foot	0.000	0.998	0.002
I42.2 Other hypertrophic cardiomyopathy	0.002	0.998	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.998	0.002
S90.8 Other superficial injuries of ankle and foot	0.000	0.998	0.002
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.998	0.002
S90.2 Contusion of toe(s) with damage to nail	0.000	0.998	0.002
S93.40 Sprain of unspecified ligament of ankle	0.000	0.998	0.002
Q12.0 Congenital cataract	0.000	0.998	0.002
S99.8 Other specified injuries of ankle and foot	0.000	0.998	0.002
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.998	0.002
I99 Other and unspecified disorders of circulatory system	0.000	0.998	0.002
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.998	0.002
I20.0 Unstable angina	0.002	0.998	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.002	0.998	0.000
S99.9 Unspecified injury of ankle and foot	0.000	0.998	0.002
E83.5 Disorders of calcium metabolism	0.000	0.998	0.002
M87.9 Osteonecrosis, unspecified	0.002	0.998	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.000	0.998	0.002
S90.0 Contusion of ankle	0.000	0.998	0.002
S91.1 Open wound of toe(s) without damage to nail	0.000	0.998	0.002
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
S91.7 Multiple open wounds of ankle and foot	0.000	0.998	0.002
S91.2 Open wound of toe(s) with damage to nail	0.000	0.998	0.002
S93.0 Dislocation of ankle joint	0.000	0.998	0.002
Q53.1 Undescended testicle, unilateral	0.002	0.998	0.000
R47.0 Dysphasia and aphasia	0.000	0.998	0.002
F02 Dementia in other diseases classified elsewhere	0.002	0.998	0.000
M21.1 Varus deformity, not elsewhere classified	0.002	0.998	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.998	0.002
Q55.6 Other congenital malformations of penis	0.002	0.998	0.000
Z63.8 Other specified problems related to primary support group	0.002	0.998	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.000	0.998	0.002
T79.5 Traumatic anuria	0.002	0.998	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.002	0.998	0.000
T79.6 Traumatic ischaemia of muscle	0.002	0.998	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.998	0.002
M87.96 Osteonecrosis, unspecified (Lower leg)	0.002	0.998	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.002	0.998	0.000
H43.8 Other disorders of vitreous body	0.002	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
Q53 Undescended testicle	0.002	0.998	0.000
S91.0 Open wound of ankle	0.000	0.998	0.002
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.002	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.002	0.998	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.998	0.002
F60.9 Personality disorder, unspecified	0.000	0.998	0.002
I20.1 Angina pectoris with documented spasm	0.000	0.998	0.002
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.002	0.998	0.000
K12 Stomatitis and related lesions	0.000	0.998	0.002
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.002	0.998	0.000
Q50.3 Other congenital malformations of ovary	0.002	0.998	0.000
Q50.2 Congenital torsion of ovary	0.002	0.998	0.000
Q50.1 Developmental ovarian cyst	0.002	0.998	0.000
Q50.0 Congenital absence of ovary	0.002	0.998	0.000
T79.8 Other early complications of trauma	0.002	0.998	0.000
O63 Long labour	0.002	0.998	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.998	0.002
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.002	0.998	0.000
M94.26 Chondromalacia (Lower leg)	0.002	0.998	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.002	0.998	0.000
F02.0 Dementia in Pick's disease	0.002	0.998	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.998	0.002
L28.0 Lichen simplex chronicus	0.000	0.998	0.002
F00 Dementia in Alzheimer's disease	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.002	0.998	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.002	0.998	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.002	0.998	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.002	0.998	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.002	0.998	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.002	0.998	0.000
H40.9 Glaucoma, unspecified	0.000	0.998	0.002
D07.5 Prostate	0.002	0.998	0.000
E29.1 Testicular hypofunction	0.002	0.998	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.001	0.998	0.000
F02.2 Dementia in Huntington's disease	0.001	0.998	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.001	0.998	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.001	0.998	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.001	0.998	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.001	0.998	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.000	0.998	0.002
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.001
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.998	0.001
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.998	0.001
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.998	0.001
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.001
M87.2 Osteonecrosis due to previous trauma	0.002	0.998	0.000
Q52.5 Fusion of labia	0.001	0.998	0.000
T79.9 Unspecified early complication of trauma	0.001	0.998	0.000
T79.4 Traumatic shock	0.001	0.998	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.001	0.998	0.000
T79.1 Fat embolism (traumatic)	0.001	0.998	0.000
T79.0 Air embolism (traumatic)	0.001	0.998	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.998	0.002
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.998	0.002
D37.7 Other digestive organs	0.000	0.998	0.002
G25.0 Essential tremor	0.000	0.998	0.002
Q87.4 Marfan's syndrome	0.002	0.998	0.000
R27.0 Ataxia, unspecified	0.000	0.998	0.002
M00.9 Pyogenic arthritis, unspecified	0.002	0.998	0.000
W22.9 Unspecified place	0.000	0.998	0.002
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
C71.1 Frontal lobe	0.000	0.998	0.002
Q53.9 Undescended testicle, unspecified	0.001	0.998	0.000
Q53.2 Undescended testicle, bilateral	0.001	0.998	0.000
Q53.0 Ectopic testis	0.001	0.998	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.001	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.001	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.001	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.001	0.998	0.000
Q55.3 Atresia of vas deferens	0.001	0.998	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.001	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.001	0.998	0.000
Q55.0 Absence and aplasia of testis	0.001	0.998	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.998	0.002
K12.0 Recurrent oral aphthae	0.000	0.998	0.001
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.002	0.998	0.000
M87 Osteonecrosis	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.001	0.998	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.001	0.998	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.001	0.998	0.000
Q51.4 Unicornate uterus	0.001	0.998	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.001	0.998	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.001	0.998	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.001	0.998	0.000
K63.9 Disease of intestine, unspecified	0.000	0.998	0.002
I61 Intracerebral haemorrhage	0.000	0.998	0.001
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.001	0.999	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.001	0.999	0.000
N60.0 Solitary cyst of breast	0.001	0.999	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.001	0.999	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.001	0.999	0.000
Q52.7 Other congenital malformations of vulva	0.001	0.999	0.000
Q52.6 Congenital malformation of clitoris	0.001	0.999	0.000
Q52.4 Other congenital malformations of vagina	0.001	0.999	0.000
Q52.3 Imperforate hymen	0.001	0.999	0.000
Q52.2 Congenital rectovaginal fistula	0.001	0.999	0.000
Q52.1 Doubling of vagina	0.001	0.999	0.000
Q52.0 Congenital absence of vagina	0.001	0.999	0.000
Q12 Congenital lens malformations	0.000	0.999	0.001
C34.9 Bronchus or lung, unspecified	0.001	0.999	0.000
K83.8 Other specified diseases of biliary tract	0.000	0.999	0.001
Q51.3 Bicornate uterus	0.001	0.999	0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.000	0.999	0.001
H43.9 Disorder of vitreous body, unspecified	0.001	0.999	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.001	0.999	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.001	0.999	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.001	0.999	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.001	0.999	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.001	0.999	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.001	0.999	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.001	0.999	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.001	0.999	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.001	0.999	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.001	0.999	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.001	0.999	0.000
F01.1 Multi-infarct dementia	0.001	0.999	0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.001	0.999	0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.001	0.999	0.000
M00.98 Pyogenic arthritis, unspecified (Other)	0.001	0.999	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.001	0.999	0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.001	0.999	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.999	0.001
H04.4 Chronic inflammation of lachrymal passages	0.000	0.999	0.001
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.001	0.999	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.001	0.999	0.000
Q51.6 Embryonic cyst of cervix	0.001	0.999	0.000
Q51.5 Agenesis and aplasia of cervix	0.001	0.999	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.001	0.999	0.000
Q51.0 Agenesis and aplasia of uterus	0.001	0.999	0.000
F01 Vascular dementia	0.001	0.999	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.999	0.001
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.001	0.999	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.001	0.999	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.001	0.999	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.001	0.999	0.000
M87.3 Other secondary osteonecrosis	0.001	0.999	0.000
M87.1 Osteonecrosis due to drugs	0.001	0.999	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.001	0.999	0.000
Q56.4 Indeterminate sex, unspecified	0.001	0.999	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.001	0.999	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.001	0.999	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.001	0.999	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.001	0.999	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.001	0.999	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.001	0.999	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.001	0.999	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.001	0.999	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.999	0.001
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.999	0.001
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.999	0.001
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.001	0.999	0.000
Q54 Hypospadias	0.001	0.999	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.001	0.999	0.000
M62.99 Disorder of muscle, unspecified (Site unspecified)	0.001	0.999	0.000
C48.0 Retroperitoneum	0.001	0.999	0.000
H69.8 Other specified disorders of Eustachian tube	0.000	0.999	0.001
I61.8 Other intracerebral haemorrhage	0.000	0.999	0.001
K12.2 Cellulitis and abscess of mouth	0.000	0.999	0.001
M85.8 Other specified disorders of bone density and structure	0.001	0.999	0.000
Q12.9 Congenital lens malformation, unspecified	0.000	0.999	0.001
Q12.8 Other congenital lens malformations	0.000	0.999	0.001
Q12.4 Spherophakia	0.000	0.999	0.001
Q12.3 Congenital aphakia	0.000	0.999	0.001
Q12.2 Coloboma of lens	0.000	0.999	0.001
Q12.1 Congenital displaced lens	0.000	0.999	0.001
Q51.2 Other doubling of uterus	0.001	0.999	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.001	0.999	0.000
E27.1 Primary adrenocortical insufficiency	0.001	0.999	0.000
G80.1 Spastic diplegia	0.001	0.999	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.999	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.999	0.001
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.001	0.999	0.000
M90.7 Fracture of bone in neoplastic disease	0.001	0.999	0.000
F09 Unspecified organic or symptomatic mental disorder	0.001	0.999	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.001	0.999	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.999	0.001
S42.10 Fracture of scapula (closed)	0.000	0.999	0.001
E78.9 Disorder of lipoprotein metabolism, unspecified	0.001	0.999	0.000
F01.8 Other vascular dementia	0.001	0.999	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.001	0.999	0.000
F01.2 Subcortical vascular dementia	0.001	0.999	0.000
F01.0 Vascular dementia of acute onset	0.001	0.999	0.000
M43.1 Spondylolisthesis	0.001	0.999	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.001	0.999	0.000
S61.0 Open wound of finger(s) without damage to nail	0.000	0.999	0.001
K12.3 Oral mucositis (ulcerative)	0.000	0.999	0.001
M21.8 Other specified acquired deformities of limbs	0.001	0.999	0.000
M87.8 Other osteonecrosis	0.001	0.999	0.000
Q66.8 Other congenital deformities of feet	0.001	0.999	0.000
Q82.5 Congenital nonneoplastic naevus	0.001	0.999	0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.001	0.999	0.000
C46 Kaposi's sarcoma	0.001	0.999	0.000
F03 Unspecified dementia	0.001	0.999	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.001	0.999	0.000
M43.12 Spondylolisthesis (Cervical region)	0.001	0.999	0.000
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.001	0.999	0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.001	0.999	0.000
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.001	0.999	0.000
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.001	0.999	0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.001	0.999	0.000
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.001	0.999	0.000
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.001	0.999	0.000
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.001	0.999	0.000
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.001	0.999	0.000
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.001	0.999	0.000
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.001	0.999	0.000
M87.18 Osteonecrosis due to drugs (Other)	0.001	0.999	0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.001	0.999	0.000
M87.16 Osteonecrosis due to drugs (Lower leg)	0.001	0.999	0.000
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.001	0.999	0.000
M87.14 Osteonecrosis due to drugs (Hand)	0.001	0.999	0.000
M87.13 Osteonecrosis due to drugs (Forearm)	0.001	0.999	0.000
M87.12 Osteonecrosis due to drugs (Upper arm)	0.001	0.999	0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.001	0.999	0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.001	0.999	0.000
M87.39 Other secondary osteonecrosis (Site unspecified)	0.001	0.999	0.000
M87.38 Other secondary osteonecrosis (Other)	0.001	0.999	0.000
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.001	0.999	0.000
M87.36 Other secondary osteonecrosis (Lower leg)	0.001	0.999	0.000
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)	0.001	0.999	0.000
M87.34 Other secondary osteonecrosis (Hand)	0.001	0.999	0.000
M87.33 Other secondary osteonecrosis (Forearm)	0.001	0.999	0.000
M87.32 Other secondary osteonecrosis (Upper arm)	0.001	0.999	0.000
M87.31 Other secondary osteonecrosis (Shoulder region)	0.001	0.999	0.000
M87.30 Other secondary osteonecrosis (Multiple sites)	0.001	0.999	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.001	0.999	0.000
H73.8 Other specified disorders of tympanic membrane	0.001	0.999	0.000
I49.8 Other specified cardiac arrhythmias	0.001	0.999	0.000
M62.9 Disorder of muscle, unspecified	0.001	0.999	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.001	0.999	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.001	0.999	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.001	0.999	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.999	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.001	0.999	0.000
C49.5 Connective and soft tissue of pelvis	0.001	0.999	0.000
F07.0 Organic personality disorder	0.001	0.999	0.000
G80.0 Spastic cerebral palsy	0.001	0.999	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.999	0.001
Q54.8 Other hypospadias	0.001	0.999	0.000
Q54.4 Congenital chordee	0.001	0.999	0.000
Q54.3 Hypospadias, perineal	0.001	0.999	0.000
Q54.2 Hypospadias, penoscrotal	0.001	0.999	0.000
Q54.1 Hypospadias, penile	0.001	0.999	0.000
G80 Infantile cerebral palsy	0.001	0.999	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.001	0.999	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.001	0.999	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.001	0.999	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.001	0.999	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.001	0.999	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.001	0.999	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.001	0.999	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.001	0.999	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.001	0.999	0.000
F01.9 Vascular dementia, unspecified	0.001	0.999	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.001	0.999	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.001	0.999	0.000
F07.2 Postconcussional syndrome	0.001	0.999	0.000
F07.1 Postencephalitic syndrome	0.001	0.999	0.000
G80.8 Other infantile cerebral palsy	0.001	0.999	0.000
H53.9 Visual disturbance, unspecified	0.000	0.999	0.001
Q66.6 Other congenital valgus deformities of feet	0.001	0.999	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.001	0.999	0.000
S91.3 Open wound of other parts of foot	0.000	0.999	0.001
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.001	0.999	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.001	0.999	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.001	0.999	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.001	0.999	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.001	0.999	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.001	0.999	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.001	0.999	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.001	0.999	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.001	0.999	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.001	0.999	0.000
M62.66 Muscle strain (Lower leg)	0.001	0.999	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.001	0.999	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.001	0.999	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.001	0.999	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.001	0.999	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.001	0.999	0.000
G80.2 Infantile hemiplegia	0.001	0.999	0.000
M89.8 Other specified disorders of bone	0.001	0.999	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.999	0.001
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.001	0.999	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.001	0.999	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.001	0.999	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.001	0.999	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.001	0.999	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.001	0.999	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.001	0.999	0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M43.15 Spondylolisthesis (Thoracolumbar region)	0.001	0.999	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.001	0.999	0.000
M43.13 Spondylolisthesis (Cervicothoracic region)	0.001	0.999	0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M43.10 Spondylolisthesis (Multiple sites in spine)	0.001	0.999	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.001	0.999	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations