TreeWAS – Variant ID: rs6422354

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K22.4 Dyskinesia of oesophagus	0.019	0.981	0.000
K22.2 Oesophageal obstruction	0.018	0.982	0.000
K22 Other diseases of oesophagus	0.018	0.982	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.017	0.983	0.000
K22.9 Disease of oesophagus, unspecified	0.016	0.984	0.000
K22.5 Diverticulum of oesophagus, acquired	0.015	0.985	0.000
K22.7 Barrett's oesophagus	0.014	0.986	0.000
K22.3 Perforation of oesophagus	0.014	0.986	0.000
I47.1 Supraventricular tachycardia	0.000	0.987	0.013
K22.0 Achalasia of cardia	0.012	0.987	0.000
C77.3 Axillary and upper limb lymph nodes	0.000	0.988	0.012
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.011	0.989	0.000
T42.4 Benzodiazepines	0.011	0.989	0.000
R20.2 Paraesthesia of skin	0.010	0.990	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.009	0.991	0.000
K22.1 Ulcer of oesophagus	0.009	0.991	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.008	0.992	0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.008	0.992	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.007	0.993	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.007	0.993	0.000
I80 Phlebitis and thrombophlebitis	0.007	0.993	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.007	0.993	0.000
T42.1 Iminostilbenes	0.007	0.993	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.007	0.993	0.000
T42.3 Barbiturates	0.007	0.993	0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.007	0.993	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.007	0.993	0.000
T39.0 Salicylates	0.007	0.993	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.007	0.993	0.000
T42.2 Succinimides and oxazolidinediones	0.007	0.993	0.000
T42.0 Hydantoin derivatives	0.007	0.993	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.007	0.993	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.007	0.993	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.007	0.993	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.007	0.993	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.007	0.993	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.006	0.993	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.006	0.993	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.006	0.994	0.000
T39.1 4-Aminophenol derivatives	0.006	0.994	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.006	0.994	0.000
E66.8 Other obesity	0.006	0.994	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.006	0.994	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.006	0.994	0.000
H81 Disorders of vestibular function	0.000	0.994	0.006
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.006	0.994	0.000
H81.2 Vestibular neuronitis	0.000	0.994	0.006
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.006	0.994	0.000
T36 Poisoning by systemic antibiotics	0.006	0.994	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.006	0.994	0.000
I89.0 Lymphoedema, not elsewhere classified	0.006	0.994	0.000
I47 Paroxysmal tachycardia	0.000	0.994	0.006
T41 Poisoning by anaesthetics and therapeutic gases	0.006	0.994	0.000
T43.6 Psychostimulants with abuse potential	0.006	0.994	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.006	0.994	0.000
H83 Other diseases of inner ear	0.000	0.994	0.006
H83.0 Labyrinthitis	0.000	0.994	0.006
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.006	0.994	0.000
E66.9 Obesity, unspecified	0.006	0.994	0.000
T39.4 Antirheumatics, not elsewhere classified	0.005	0.994	0.000
T39.2 Pyrazolone derivatives	0.005	0.994	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.006	0.994	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.005	0.994	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.994	0.000
H80-H83 Diseases of inner ear	0.000	0.994	0.006
I73.9 Peripheral vascular disease, unspecified	0.005	0.995	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
I87 Other disorders of veins	0.005	0.995	0.000
T38.1 Thyroid hormones and substitutes	0.005	0.995	0.000
E66 Obesity	0.005	0.995	0.000
T43.2 Other and unspecified antidepressants	0.005	0.995	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.005	0.995	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.005	0.995	0.000
O02.1 Missed abortion	0.005	0.995	0.000
T40.6 Other and unspecified narcotics	0.005	0.995	0.000
T40.5 Cocaine	0.005	0.995	0.000
T45.0 Antiallergic and antiemetic drugs	0.005	0.995	0.000
H80 Otosclerosis	0.000	0.995	0.005
T45.1 Antineoplastic and immunosuppressive drugs	0.005	0.995	0.000
I47.2 Ventricular tachycardia	0.000	0.995	0.005
H81.0 Meniere's disease	0.000	0.995	0.005
H80.9 Otosclerosis, unspecified	0.000	0.995	0.005
T40.3 Methadone	0.005	0.995	0.000
T43.9 Psychotropic drug, unspecified	0.005	0.995	0.000
T45.4 Iron and its compounds	0.005	0.995	0.000
T40.4 Other synthetic narcotics	0.005	0.995	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.005	0.995	0.000
I85 Oesophageal varices	0.005	0.995	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.005	0.995	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.005	0.995	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.005	0.995	0.000
T45.2 Vitamins, not elsewhere classified	0.005	0.995	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.005	0.995	0.000
T40.8 Lysergide [LSD]	0.005	0.995	0.000
T40.7 Cannabis (derivatives)	0.005	0.995	0.000
T40.0 Opium	0.005	0.995	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.005	0.995	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.005	0.995	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.005	0.995	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.005	0.995	0.000
T44.0 Anticholinesterase agents	0.005	0.995	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.005	0.995	0.000
T45.8 Other primarily systemic and haematological agents	0.005	0.995	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.005	0.995	0.000
T45.6 Fibrinolysis-affecting drugs	0.005	0.995	0.000
T45.3 Enzymes, not elsewhere classified	0.005	0.995	0.000
H83.9 Disease of inner ear, unspecified	0.000	0.995	0.005
I87.2 Venous insufficiency (chronic) (peripheral)	0.005	0.995	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.005	0.995	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.005	0.995	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.005	0.995	0.000
I87.8 Other specified disorders of veins	0.005	0.995	0.000
N93.0 Postcoital and contact bleeding	0.005	0.995	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.005	0.995	0.000
T36.0 Penicillins	0.005	0.995	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.005	0.995	0.000
H81.8 Other disorders of vestibular function	0.000	0.995	0.005
T38.9 Other and unspecified hormone antagonists	0.005	0.995	0.000
T38.7 Androgens and anabolic congeners	0.005	0.995	0.000
T38.4 Oral contraceptives	0.005	0.995	0.000
T38.2 Antithyroid drugs	0.005	0.995	0.000
T38.0 Glucocorticoids and synthetic analogues	0.005	0.995	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.995	0.000
N93 Other abnormal uterine and vaginal bleeding	0.005	0.995	0.000
G47.3 Sleep apnoea	0.005	0.995	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.005	0.995	0.000
T40.1 Heroin	0.005	0.995	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.005	0.995	0.000
T48.5 Anti-common-cold drugs	0.005	0.995	0.000
H81.1 Benign paroxysmal vertigo	0.000	0.995	0.005
T43.5 Other and unspecified antipsychotics and neuroleptics	0.005	0.995	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.005	0.995	0.000
T37.5 Antiviral drugs	0.005	0.995	0.000
T37.4 Anthelminthics	0.005	0.995	0.000
T37.3 Other antiprotozoal drugs	0.005	0.995	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.005	0.995	0.000
T37.1 Antimycobacterial drugs	0.005	0.995	0.000
T37.0 Sulphonamides	0.005	0.995	0.000
E24 Cushing's syndrome	0.005	0.995	0.000
H81.4 Vertigo of central origin	0.000	0.995	0.005
H81.3 Other peripheral vertigo	0.000	0.995	0.005
R20 Disturbances of skin sensation	0.005	0.995	0.000
E24.9 Cushing's syndrome, unspecified	0.005	0.995	0.000
I88 Nonspecific lymphadenitis	0.005	0.995	0.000
T45.5 Anticoagulants	0.005	0.995	0.000
I81 Portal vein thrombosis	0.005	0.995	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.004	0.995	0.000
T40.2 Other opioids	0.005	0.995	0.000
I85.9 Oesophageal varices without bleeding	0.005	0.995	0.000
T49.9 Topical agent, unspecified	0.004	0.995	0.000
T49.8 Other topical agents	0.004	0.995	0.000
T49.7 Dental drugs, topically applied	0.004	0.995	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.004	0.995	0.000
T49.5 Ophthalmological drugs and preparations	0.004	0.995	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.004	0.995	0.000
T49.3 Emollients, demulcents and protectants	0.004	0.995	0.000
T49.2 Local astringents and local detergents	0.004	0.995	0.000
T49.1 Antipruritics	0.004	0.995	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.995	0.000
T48.4 Expectorants	0.004	0.995	0.000
T48.3 Antitussives	0.004	0.995	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.004	0.995	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.995	0.000
T48.0 Oxytocic drugs	0.004	0.995	0.000
T36.9 Systemic antibiotic, unspecified	0.004	0.995	0.000
T36.8 Other systemic antibiotics	0.004	0.995	0.000
T36.7 Antifungal antibiotics, systemically used	0.004	0.995	0.000
T36.6 Rifamycins	0.004	0.995	0.000
T36.5 Aminoglycosides	0.004	0.995	0.000
T36.2 Chloramphenicol group	0.004	0.995	0.000
H83.8 Other specified diseases of inner ear	0.000	0.995	0.004
T50.8 Diagnostic agents	0.004	0.995	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.004	0.995	0.000
I82 Other venous embolism and thrombosis	0.004	0.995	0.000
T38.5 Other oestrogens and progestogens	0.004	0.996	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.004	0.996	0.000
E20-E35 Disorders of other endocrine glands	0.004	0.996	0.000
K07.3 Anomalies of tooth position	0.000	0.996	0.004
E22 Hyperfunction of pituitary gland	0.004	0.996	0.000
T36.4 Tetracyclines	0.004	0.996	0.000
T41.5 Therapeutic gases	0.004	0.996	0.000
T41.4 Anaesthetic, unspecified	0.004	0.996	0.000
T41.3 Local anaesthetics	0.004	0.996	0.000
T41.1 Intravenous anaesthetics	0.004	0.996	0.000
T41.0 Inhaled anaesthetics	0.004	0.996	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.004	0.996	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.004	0.996	0.000
H83.1 Labyrinthine fistula	0.000	0.996	0.004
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.004	0.996	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.004	0.996	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.004	0.996	0.000
H83.2 Labyrinthine dysfunction	0.000	0.996	0.004
I87.0 Postphlebitic syndrome	0.004	0.996	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.000	0.996	0.004
T36.3 Macrolides	0.004	0.996	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.004	0.996	0.000
E21.3 Hyperparathyroidism, unspecified	0.004	0.996	0.000
T41.2 Other and unspecified general anaesthetics	0.004	0.996	0.000
T50.4 Drugs affecting uric acid metabolism	0.004	0.996	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.000	0.996	0.004
H83.3 Noise effects on inner ear	0.000	0.996	0.004
N28.1 Cyst of kidney, acquired	0.004	0.996	0.000
T50.7 Analeptics and opioid receptor antagonists	0.004	0.996	0.000
T50.5 Appetite depressants	0.004	0.996	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.004	0.996	0.000
T50.1 Loop [high-ceiling] diuretics	0.004	0.996	0.000
T50.0 Mineralocorticoids and their antagonists	0.004	0.996	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.004	0.996	0.000
K22.8 Other specified diseases of oesophagus	0.004	0.996	0.000
E66.1 Drug-induced obesity	0.004	0.996	0.000
I87.9 Disorder of vein, unspecified	0.004	0.996	0.000
E24.0 Pituitary-dependent Cushing's disease	0.004	0.996	0.000
H81.9 Disorder of vestibular function, unspecified	0.000	0.996	0.004
E87.6 Hypokalaemia	0.004	0.996	0.000
H80.2 Cochlear otosclerosis	0.000	0.996	0.004
H80.1 Otosclerosis involving oval window, obliterative	0.000	0.996	0.004
O46.9 Antepartum haemorrhage, unspecified	0.004	0.996	0.000
O43 Placental disorders	0.004	0.996	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.004	0.996	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.004	0.996	0.000
O40 Polyhydramnios	0.004	0.996	0.000
I82.8 Embolism and thrombosis of other specified veins	0.004	0.996	0.000
R20.0 Anaesthesia of skin	0.004	0.996	0.000
E22.0 Acromegaly and pituitary gigantism	0.004	0.996	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.996	0.004
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.004	0.996	0.000
I85.0 Oesophageal varices with bleeding	0.004	0.996	0.000
I47.0 Reentry ventricular arrhythmia	0.000	0.996	0.004
T46.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.004	0.996	0.000
I87.1 Compression of vein	0.004	0.996	0.000
I89.1 Lymphangitis	0.004	0.996	0.000
H80.8 Other otosclerosis	0.000	0.996	0.004
I88.0 Nonspecific mesenteric lymphadenitis	0.004	0.996	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
O47 False labour	0.004	0.996	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.004	0.996	0.000
O43.8 Other placental disorders	0.004	0.996	0.000
J00 Acute nasopharyngitis [common cold]	0.000	0.996	0.004
I88.8 Other nonspecific lymphadenitis	0.004	0.996	0.000
E24.8 Other Cushing's syndrome	0.004	0.996	0.000
T47.6 Antidiarrhoeal drugs	0.004	0.996	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.004	0.996	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.004	0.996	0.000
T47.7 Emetics	0.004	0.996	0.000
T47.5 Digestants	0.004	0.996	0.000
T47.3 Saline and osmotic laxatives	0.004	0.996	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.004	0.996	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.004	0.996	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.004	0.996	0.000
R20.3 Hyperaesthesia	0.004	0.996	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
T47.0 Histamine H(2)-receptor antagonists	0.003	0.996	0.000
E20 Hypoparathyroidism	0.004	0.996	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.004	0.996	0.000
T46.7 Peripheral vasodilators	0.004	0.996	0.000
T47.4 Other laxatives	0.003	0.996	0.000
E26 Hyperaldosteronism	0.004	0.996	0.000
O31 Complications specific to multiple gestation	0.004	0.996	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.004	0.996	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.004	0.996	0.000
E24.2 Drug-induced Cushing's syndrome	0.004	0.996	0.000
E21.2 Other hyperparathyroidism	0.004	0.996	0.000
I82.2 Embolism and thrombosis of vena cava	0.004	0.996	0.000
O34.4 Maternal care for other abnormalities of cervix	0.004	0.996	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.004	0.996	0.000
E24.3 Ectopic ACTH syndrome	0.004	0.996	0.000
E24.1 Nelson's syndrome	0.004	0.996	0.000
E21.4 Other specified disorders of parathyroid gland	0.004	0.996	0.000
E32 Diseases of thymus	0.004	0.996	0.000
O32.0 Maternal care for unstable lie	0.004	0.996	0.000
O02 Other abnormal products of conception	0.004	0.996	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.003	0.996	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.996	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.003	0.996	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.003	0.996	0.000
N93.8 Other specified abnormal uterine and vaginal bleeding	0.004	0.996	0.000
R20.1 Hypoaesthesia of skin	0.003	0.996	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.003	0.996	0.000
E31 Polyglandular dysfunction	0.003	0.996	0.000
T47.2 Stimulant laxatives	0.003	0.996	0.000
I82.1 Thrombophlebitis migrans	0.003	0.996	0.000
O34.3 Maternal care for cervical incompetence	0.003	0.996	0.000
E25 Adrenogenital disorders	0.003	0.996	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.003	0.997	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E30 Disorders of puberty, not elsewhere classified	0.003	0.997	0.000
E22.8 Other hyperfunction of pituitary gland	0.003	0.997	0.000
O34.6 Maternal care for abnormality of vagina	0.003	0.997	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
I86 Varicose veins of other sites	0.003	0.997	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.003	0.997	0.000
K07 Dentofacial anomalies [including malocclusion]	0.000	0.997	0.003
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.003	0.997	0.000
E21.0 Primary hyperparathyroidism	0.003	0.997	0.000
O32.2 Maternal care for transverse and oblique lie	0.003	0.997	0.000
O47.0 False labour before 37 completed weeks of gestation	0.003	0.997	0.000
O33 Maternal care for known or suspected disproportion	0.003	0.997	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.003	0.997	0.000
O43.0 Placental transfusion syndromes	0.003	0.997	0.000
K07.6 Temporomandibular joint disorders	0.000	0.997	0.003
O32.3 Maternal care for face, brow and chin presentation	0.003	0.997	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
D69.6 Thrombocytopenia, unspecified	0.000	0.997	0.003
E66.0 Obesity due to excess calories	0.003	0.997	0.000
E29 Testicular dysfunction	0.003	0.997	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.003	0.997	0.000
O30 Multiple gestation	0.003	0.997	0.000
E65-E68 Obesity and other hyperalimentation	0.003	0.997	0.000
O32.4 Maternal care for high head at term	0.003	0.997	0.000
O45 Premature separation of placenta [abruptio placentae]	0.003	0.997	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.003	0.997	0.000
O34.1 Maternal care for tumour of corpus uteri	0.003	0.997	0.000
E20.9 Hypoparathyroidism, unspecified	0.003	0.997	0.000
O43.9 Placental disorder, unspecified	0.003	0.997	0.000
E28 Ovarian dysfunction	0.003	0.997	0.000
E22.1 Hyperprolactinaemia	0.003	0.997	0.000
I82.0 Budd-Chiari syndrome	0.003	0.997	0.000
O43.2 Morbidly adherent placenta	0.003	0.997	0.000
K07.4 Malocclusion, unspecified	0.000	0.997	0.003
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.003	0.997	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.003	0.997	0.000
E26.9 Hyperaldosteronism, unspecified	0.003	0.997	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.003	0.997	0.000
E27 Other disorders of adrenal gland	0.003	0.997	0.000
I86.4 Gastric varices	0.003	0.997	0.000
O31.8 Other complications specific to multiple gestation	0.003	0.997	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.997	0.003
I82.3 Embolism and thrombosis of renal vein	0.003	0.997	0.000
O34.0 Maternal care for congenital malformation of uterus	0.003	0.997	0.000
O32.6 Maternal care for compound presentation	0.003	0.997	0.000
E26.0 Primary hyperaldosteronism	0.003	0.997	0.000
E20.8 Other hypoparathyroidism	0.003	0.997	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.003	0.997	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.003	0.997	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.003	0.997	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.003	0.997	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.003	0.997	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.003	0.997	0.000
T46.1 Calcium-channel blockers	0.003	0.997	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.003	0.997	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.003	0.997	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.997	0.003
E34 Other endocrine disorders	0.003	0.997	0.000
E20.0 Idiopathic hypoparathyroidism	0.003	0.997	0.000
E20.1 Pseudohypoparathyroidism	0.003	0.997	0.000
E26.8 Other hyperaldosteronism	0.003	0.997	0.000
E26.1 Secondary hyperaldosteronism	0.003	0.997	0.000
E32.9 Disease of thymus, unspecified	0.003	0.997	0.000
E32.8 Other diseases of thymus	0.003	0.997	0.000
O31.0 Papyraceous foetus	0.003	0.997	0.000
O48 Prolonged pregnancy	0.003	0.997	0.000
O43.1 Malformation of placenta	0.003	0.997	0.000
O46.8 Other antepartum haemorrhage	0.003	0.997	0.000
O32.8 Maternal care for other malpresentation of foetus	0.003	0.997	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.003	0.997	0.000
O44 Placenta praevia	0.003	0.997	0.000
E32.1 Abscess of thymus	0.003	0.997	0.000
E32.0 Persistent hyperplasia of thymus	0.003	0.997	0.000
K07.2 Anomalies of dental arch relationship	0.000	0.997	0.003
I83 Varicose veins of lower extremities	0.003	0.997	0.000
E31.0 Autoimmune polyglandular failure	0.003	0.997	0.000
O02.9 Abnormal product of conception, unspecified	0.003	0.997	0.000
O02.8 Other specified abnormal products of conception	0.003	0.997	0.000
O30.1 Triplet pregnancy	0.003	0.997	0.000
R22.1 Localised swelling, mass and lump, neck	0.003	0.997	0.000
K07.8 Other dentofacial anomalies	0.000	0.997	0.003
K07.5 Dentofacial functional abnormalities	0.000	0.997	0.003
O33.5 Maternal care for disproportion due to unusually large foetus	0.003	0.997	0.000
E27.8 Other specified disorders of adrenal gland	0.003	0.997	0.000
E31.9 Polyglandular dysfunction, unspecified	0.003	0.997	0.000
E31.8 Other polyglandular dysfunction	0.003	0.997	0.000
E31.1 Polyglandular hyperfunction	0.003	0.997	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.003	0.997	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.003	0.997	0.000
J81 Pulmonary oedema	0.003	0.997	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.003	0.997	0.000
E25.9 Adrenogenital disorder, unspecified	0.003	0.997	0.000
E25.8 Other adrenogenital disorders	0.003	0.997	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.003	0.997	0.000
E30.9 Disorder of puberty, unspecified	0.003	0.997	0.000
E30.8 Other disorders of puberty	0.003	0.997	0.000
E30.1 Precocious puberty	0.003	0.997	0.000
E30.0 Delayed puberty	0.003	0.997	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.003	0.997	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.003	0.997	0.000
D69.5 Secondary thrombocytopenia	0.000	0.997	0.003
I86.0 Sublingual varices	0.003	0.997	0.000
O33.8 Maternal care for disproportion of other origin	0.003	0.997	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.003	0.997	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.003	0.997	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.003	0.997	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.003	0.997	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.003	0.997	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.003	0.997	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.003	0.997	0.000
N83.1 Corpus luteum cyst	0.000	0.997	0.003
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.003	0.997	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.003	0.997	0.000
O33.9 Maternal care for disproportion, unspecified	0.003	0.997	0.000
Y42.7 Androgens and anabolic congeners	0.003	0.997	0.000
E29.8 Other testicular dysfunction	0.003	0.997	0.000
E29.0 Testicular hyperfunction	0.003	0.997	0.000
K07.0 Major anomalies of jaw size	0.000	0.997	0.003
I73 Other peripheral vascular diseases	0.003	0.997	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.000	0.997	0.003
E27.2 Addisonian crisis	0.003	0.997	0.000
O30.9 Multiple gestation, unspecified	0.002	0.997	0.000
O30.8 Other multiple gestation	0.002	0.997	0.000
O30.2 Quadruplet pregnancy	0.002	0.997	0.000
E23 Hypofunction and other disorders of pituitary gland	0.003	0.997	0.000
E67 Other hyperalimentation	0.002	0.997	0.000
E68 Sequelae of hyperalimentation	0.002	0.997	0.000
I86.3 Vulval varices	0.002	0.997	0.000
K07.9 Dentofacial anomaly, unspecified	0.000	0.997	0.003
O45.8 Other premature separation of placenta	0.002	0.997	0.000
O45.0 Premature separation of placenta with coagulation defect	0.002	0.997	0.000
O36 Maternal care for other known or suspected foetal problems	0.003	0.997	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.003	0.997	0.000
E29.1 Testicular hypofunction	0.003	0.997	0.000
O00-O08 Pregnancy with abortive outcome	0.003	0.997	0.000
E29.9 Testicular dysfunction, unspecified	0.002	0.997	0.000
O41 Other disorders of amniotic fluid and membranes	0.002	0.997	0.000
D69.2 Other nonthrombocytopenic purpura	0.000	0.997	0.002
E28.9 Ovarian dysfunction, unspecified	0.002	0.997	0.000
E28.8 Other ovarian dysfunction	0.002	0.997	0.000
E28.1 Androgen excess	0.002	0.997	0.000
E28.0 Oestrogen excess	0.002	0.997	0.000
D69.0 Allergic purpura	0.000	0.997	0.002
O45.9 Premature separation of placenta, unspecified	0.002	0.997	0.000
Y57.9 Drug or medicament, unspecified	0.003	0.997	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
E27.5 Adrenomedullary hyperfunction	0.002	0.997	0.000
E27.0 Other adrenocortical overactivity	0.002	0.997	0.000
I86.2 Pelvic varices	0.002	0.997	0.000
E28.2 Polycystic ovarian syndrome	0.002	0.997	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.002	0.997	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.003	0.997	0.000
I86.8 Varicose veins of other specified sites	0.002	0.997	0.000
D69.8 Other specified haemorrhagic conditions	0.000	0.997	0.002
E04.9 Non-toxic goitre, unspecified	0.003	0.997	0.000
N28.8 Other specified disorders of kidney and ureter	0.002	0.997	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.002	0.997	0.000
D69.4 Other primary thrombocytopenia	0.000	0.998	0.002
E34.3 Short stature, not elsewhere classified	0.002	0.998	0.000
E85 Amyloidosis	0.002	0.998	0.000
E34.5 Androgen resistance syndrome	0.002	0.998	0.000
E34.4 Constitutional tall stature	0.002	0.998	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.002	0.998	0.000
E34.1 Other hypersecretion of intestinal hormones	0.002	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
N28.0 Ischaemia and infarction of kidney	0.002	0.998	0.000
E34.8 Other specified endocrine disorders	0.002	0.998	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.002	0.998	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.998	0.002
D69.9 Haemorrhagic condition, unspecified	0.000	0.998	0.002
E85.4 Organ-limited amyloidosis	0.002	0.998	0.000
H43.8 Other disorders of vitreous body	0.000	0.998	0.002
I73.8 Other specified peripheral vascular diseases	0.002	0.998	0.000
O30.0 Twin pregnancy	0.002	0.998	0.000
O42 Premature rupture of membranes	0.002	0.998	0.000
R23 Other skin changes	0.002	0.998	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
E27.9 Disorder of adrenal gland, unspecified	0.002	0.998	0.000
O36.9 Maternal care for foetal problem, unspecified	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.002	0.998	0.000
O47.9 False labour, unspecified	0.002	0.998	0.000
G47 Sleep disorders	0.002	0.998	0.000
O04 Medical abortion	0.002	0.998	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.002	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.002	0.998	0.000
R23.4 Changes in skin texture	0.002	0.998	0.000
R23.1 Pallor	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
D69.1 Qualitative platelet defects	0.000	0.998	0.002
E85.3 Secondary systemic amyloidosis	0.002	0.998	0.000
E34.0 Carcinoid syndrome	0.002	0.998	0.000
G47.9 Sleep disorder, unspecified	0.002	0.998	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.002	0.998	0.000
E27.1 Primary adrenocortical insufficiency	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
O03 Spontaneous abortion	0.002	0.998	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.002	0.998	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.002	0.998	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
R25.1 Tremor, unspecified	0.000	0.998	0.002
Y42.4 Oral contraceptives	0.002	0.998	0.000
O36.1 Maternal care for other isoimmunisation	0.002	0.998	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
E23.1 Drug-induced hypopituitarism	0.002	0.998	0.000
E67.8 Other specified hyperalimentation	0.002	0.998	0.000
E67.3 Hypervitaminosis D	0.002	0.998	0.000
E67.2 Megavitamin-B6 syndrome	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations