TreeWAS – Variant ID: rs6435387

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.9 Chronic ischaemic heart disease, unspecified	0.012	0.988	0.000
O26.9 Pregnancy-related condition, unspecified	0.000	0.994	0.006
R42 Dizziness and giddiness	0.006	0.994	0.000
I25 Chronic ischaemic heart disease	0.005	0.995	0.000
K92.0 Haematemesis	0.004	0.996	0.000
J98.1 Pulmonary collapse	0.004	0.996	0.000
T39.1 4-Aminophenol derivatives	0.004	0.996	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.004	0.996	0.000
I25.2 Old myocardial infarction	0.004	0.996	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.004	0.996	0.000
I25.3 Aneurysm of heart	0.004	0.996	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.004	0.996	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.004	0.996	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
I25.5 Ischaemic cardiomyopathy	0.004	0.996	0.000
Z87.1 Personal history of diseases of the digestive system	0.004	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
M47.86 Other spondylosis (Lumbar region)	0.004	0.996	0.000
I25.6 Silent myocardial ischaemia	0.003	0.996	0.000
H40.1 Primary open-angle glaucoma	0.000	0.996	0.004
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.996	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.003	0.997	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
H40 Glaucoma	0.000	0.997	0.003
H40.0 Glaucoma suspect	0.000	0.997	0.003
T39.4 Antirheumatics, not elsewhere classified	0.003	0.997	0.000
T39.2 Pyrazolone derivatives	0.003	0.997	0.000
T46.1 Calcium-channel blockers	0.003	0.997	0.000
T39.0 Salicylates	0.003	0.997	0.000
H40.2 Primary angle-closure glaucoma	0.000	0.997	0.003
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.003	0.997	0.000
Z96.8 Presence of other specified functional implants	0.003	0.997	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.997	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
H40.8 Other glaucoma	0.000	0.997	0.003
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
T46.7 Peripheral vasodilators	0.003	0.997	0.000
I25.4 Coronary artery aneurysm	0.003	0.997	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.003	0.997	0.000
S01.8 Open wound of other parts of head	0.003	0.997	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.003	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.997	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
K92.2 Gastro-intestinal haemorrhage, unspecified	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.003	0.997	0.000
T36 Poisoning by systemic antibiotics	0.003	0.997	0.000
T42.1 Iminostilbenes	0.003	0.997	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.003	0.997	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.003	0.997	0.000
T42.2 Succinimides and oxazolidinediones	0.003	0.997	0.000
K92 Other diseases of digestive system	0.003	0.997	0.000
H40.3 Glaucoma secondary to eye trauma	0.000	0.997	0.003
T50.9 Other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
T50.8 Diagnostic agents	0.003	0.997	0.000
J69.0 Pneumonitis due to food and vomit	0.000	0.997	0.003
T42.0 Hydantoin derivatives	0.003	0.997	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
T42.3 Barbiturates	0.003	0.997	0.000
H40.6 Glaucoma secondary to drugs	0.000	0.997	0.003
T50.1 Loop [high-ceiling] diuretics	0.002	0.997	0.000
H40.4 Glaucoma secondary to eye inflammation	0.000	0.997	0.002
T47.0 Histamine H(2)-receptor antagonists	0.002	0.997	0.000
T50.7 Analeptics and opioid receptor antagonists	0.002	0.997	0.000
T50.5 Appetite depressants	0.002	0.997	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.997	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.997	0.000
T42.4 Benzodiazepines	0.003	0.997	0.000
T47.4 Other laxatives	0.002	0.997	0.000
T47.2 Stimulant laxatives	0.002	0.997	0.000
M47.8 Other spondylosis	0.003	0.997	0.000
H40.9 Glaucoma, unspecified	0.000	0.997	0.003
H40.5 Glaucoma secondary to other eye disorders	0.000	0.997	0.002
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.997	0.000
T47.7 Emetics	0.002	0.997	0.000
T47.5 Digestants	0.002	0.997	0.000
T47.3 Saline and osmotic laxatives	0.002	0.997	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.002	0.997	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.997	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.002	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
T41.5 Therapeutic gases	0.002	0.998	0.000
T41.4 Anaesthetic, unspecified	0.002	0.998	0.000
T41.3 Local anaesthetics	0.002	0.998	0.000
T41.1 Intravenous anaesthetics	0.002	0.998	0.000
T41.0 Inhaled anaesthetics	0.002	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
T48.4 Expectorants	0.002	0.998	0.000
T48.3 Antitussives	0.002	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
T48.0 Oxytocic drugs	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
T48.5 Anti-common-cold drugs	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
T37.5 Antiviral drugs	0.002	0.998	0.000
T37.4 Anthelminthics	0.002	0.998	0.000
T37.3 Other antiprotozoal drugs	0.002	0.998	0.000
T37.1 Antimycobacterial drugs	0.002	0.998	0.000
T37.0 Sulphonamides	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
T49.9 Topical agent, unspecified	0.002	0.998	0.000
T49.8 Other topical agents	0.002	0.998	0.000
T49.7 Dental drugs, topically applied	0.002	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.998	0.000
T49.2 Local astringents and local detergents	0.002	0.998	0.000
T49.1 Antipruritics	0.002	0.998	0.000
S01.3 Open wound of ear	0.002	0.998	0.000
T36.3 Macrolides	0.002	0.998	0.000
K92.9 Disease of digestive system, unspecified	0.002	0.998	0.000
T36.8 Other systemic antibiotics	0.002	0.998	0.000
T36.4 Tetracyclines	0.002	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.998	0.000
S01 Open wound of head	0.002	0.998	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.002	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
T44.0 Anticholinesterase agents	0.002	0.998	0.000
R45.1 Restlessness and agitation	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
T36.6 Rifamycins	0.002	0.998	0.000
T36.5 Aminoglycosides	0.002	0.998	0.000
T36.2 Chloramphenicol group	0.002	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.998	0.000
T45.4 Iron and its compounds	0.002	0.998	0.000
S01.9 Open wound of head, part unspecified	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
R49.0 Dysphonia	0.000	0.998	0.002
M47.87 Other spondylosis (Lumbosacral region)	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
T45.5 Anticoagulants	0.002	0.998	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.002	0.998	0.000
S01.5 Open wound of lip and oral cavity	0.002	0.998	0.000
R45 Symptoms and signs involving emotional state	0.002	0.998	0.000
M47.84 Other spondylosis (Thoracic region)	0.002	0.998	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.002	0.998	0.000
G93.3 Postviral fatigue syndrome	0.002	0.998	0.000
S01.1 Open wound of eyelid and periocular area	0.002	0.998	0.000
T36.0 Penicillins	0.002	0.998	0.000
M47.89 Other spondylosis (Site unspecified)	0.002	0.998	0.000
M47.82 Other spondylosis (Cervical region)	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
H21 Other disorders of iris and ciliary body	0.002	0.998	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.002	0.998	0.000
K92.8 Other specified diseases of digestive system	0.002	0.998	0.000
T43.2 Other and unspecified antidepressants	0.002	0.998	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
K59.0 Constipation	0.002	0.998	0.000
T40.5 Cocaine	0.002	0.998	0.000
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
K90.0 Coeliac disease	0.000	0.998	0.002
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
T40.1 Heroin	0.002	0.998	0.000
G93 Other disorders of brain	0.002	0.998	0.000
G93.9 Disorder of brain, unspecified	0.002	0.998	0.000
S01.4 Open wound of cheek and temporomandibular area	0.002	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.002	0.998	0.000
T40.8 Lysergide [LSD]	0.002	0.998	0.000
T40.7 Cannabis (derivatives)	0.002	0.998	0.000
T40.0 Opium	0.002	0.998	0.000
H20.9 Iridocyclitis, unspecified	0.002	0.998	0.000
H20 Iridocyclitis	0.002	0.998	0.000
T40.3 Methadone	0.002	0.998	0.000
G93.2 Benign intracranial hypertension	0.002	0.998	0.000
S01.7 Multiple open wounds of head	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
R45.4 Irritability and anger	0.002	0.998	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
R45.2 Unhappiness	0.002	0.998	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.002	0.998	0.000
R40 Somnolence, stupor and coma	0.002	0.998	0.000
H21.2 Degeneration of iris and ciliary body	0.002	0.998	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
R45.5 Hostility	0.002	0.998	0.000
T40.2 Other opioids	0.002	0.998	0.000
F10.3 Withdrawal state	0.002	0.998	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.002	0.998	0.000
H21.4 Pupillary membranes	0.002	0.998	0.000
H21.0 Hyphaema	0.002	0.998	0.000
K91.3 Postoperative intestinal obstruction	0.002	0.998	0.000
R45.7 State of emotional shock and stress, unspecified	0.002	0.998	0.000
R45.3 Demoralisation and apathy	0.002	0.998	0.000
R46 Symptoms and signs involving appearance and behaviour	0.002	0.998	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.998	0.002
G93.6 Cerebral oedema	0.002	0.998	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
D37.5 Rectum	0.002	0.998	0.000
H20.0 Acute and subacute iridocyclitis	0.002	0.998	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.002	0.998	0.000
R45.6 Physical violence	0.002	0.998	0.000
S01.2 Open wound of nose	0.002	0.998	0.000
T40.6 Other and unspecified narcotics	0.001	0.998	0.000
G93.0 Cerebral cysts	0.002	0.998	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.002	0.998	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.998	0.002
R43 Disturbances of smell and taste	0.002	0.998	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.000	0.998	0.002
H20.1 Chronic iridocyclitis	0.002	0.998	0.000
R45.0 Nervousness	0.002	0.998	0.000
G93.8 Other specified disorders of brain	0.002	0.998	0.000
G93.4 Encephalopathy, unspecified	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.002	0.998	0.000
R45.8 Other symptoms and signs involving emotional state	0.002	0.998	0.000
G93.7 Reye's syndrome	0.002	0.998	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.002	0.998	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
T40.4 Other synthetic narcotics	0.001	0.998	0.000
G93.5 Compression of brain	0.002	0.998	0.000
H20.2 Lens-induced iridocyclitis	0.001	0.998	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.998	0.002
R40.1 Stupor	0.002	0.998	0.000
R40.0 Somnolence	0.002	0.998	0.000
H17 Corneal scars and opacities	0.002	0.998	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.000	0.998	0.001
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.001	0.998	0.000
H16 Keratitis	0.002	0.998	0.000
D37.2 Small intestine	0.002	0.998	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.001	0.998	0.000
H17.9 Corneal scar and opacity, unspecified	0.001	0.998	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.001	0.998	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
R43.8 Other and unspecified disturbances of smell and taste	0.001	0.998	0.000
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.001	0.998	0.000
R46.6 Undue concern and preoccupation with stressful events	0.001	0.998	0.000
R46.5 Suspiciousness and marked evasiveness	0.001	0.998	0.000
R46.4 Slowness and poor responsiveness	0.001	0.998	0.000
R46.3 Overactivity	0.001	0.998	0.000
R46.1 Bizarre personal appearance	0.001	0.998	0.000
R46.0 Very low level of personal hygiene	0.001	0.998	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.002	0.998	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.001	0.998	0.000
O26.5 Maternal hypotension syndrome	0.000	0.998	0.001
R46.2 Strange and inexplicable behaviour	0.001	0.998	0.000
Z90.5 Acquired absence of kidney	0.002	0.998	0.000
D37.6 Liver, gallbladder and bile ducts	0.001	0.998	0.000
D37.4 Colon	0.001	0.998	0.000
D73.0 Hyposplenism	0.000	0.998	0.001
O26.4 Herpes gestationis	0.000	0.998	0.001
O26.1 Low weight gain in pregnancy	0.000	0.998	0.001
R40.2 Coma, unspecified	0.001	0.998	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.000	0.998	0.001
O26.0 Excessive weight gain in pregnancy	0.000	0.998	0.001
R43.2 Parageusia	0.001	0.998	0.000
R43.1 Parosmia	0.001	0.998	0.000
R43.0 Anosmia	0.001	0.998	0.000
H15 Disorders of sclera	0.001	0.998	0.000
Z94.8 Other transplanted organ and tissue status	0.001	0.998	0.000
R55 Syncope and collapse	0.002	0.998	0.000
H40-H42 Glaucoma	0.000	0.998	0.001
D37.3 Appendix	0.001	0.998	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.001	0.998	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.001	0.998	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.000	0.998	0.001
Z90.2 Acquired absence of lung [part of]	0.000	0.998	0.001
J69 Pneumonitis due to solids and liquids	0.000	0.998	0.001
H16.1 Other superficial keratitis without conjunctivitis	0.001	0.999	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.001	0.999	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.999	0.001
K91.2 Postsurgical malabsorption, not elsewhere classified	0.001	0.999	0.000
D37.9 Digestive organ, unspecified	0.001	0.999	0.000
H16.8 Other keratitis	0.001	0.999	0.000
H16.2 Keratoconjunctivitis	0.001	0.999	0.000
H17.1 Other central corneal opacity	0.001	0.999	0.000
H17.0 Adherent leukoma	0.001	0.999	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
S01.0 Open wound of scalp	0.001	0.999	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.001	0.999	0.000
K90-K93 Other diseases of the digestive system	0.001	0.999	0.000
H16.4 Corneal neovascularisation	0.001	0.999	0.000
H16.0 Corneal ulcer	0.001	0.999	0.000
H17.8 Other corneal scars and opacities	0.001	0.999	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.001	0.999	0.000
O26.2 Pregnancy care of habitual aborter	0.000	0.999	0.001
T43.0 Tricyclic and tetracyclic antidepressants	0.001	0.999	0.000
K90 Intestinal malabsorption	0.001	0.999	0.001
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.001	0.999	0.000
C43.9 Malignant melanoma of skin, unspecified	0.000	0.999	0.001
D37.1 Stomach	0.001	0.999	0.000
K91.5 Postcholecystectomy syndrome	0.001	0.999	0.000
K91.1 Postgastric surgery syndromes	0.001	0.999	0.000
D37.0 Lip, oral cavity and pharynx	0.001	0.999	0.000
H15.9 Disorder of sclera, unspecified	0.001	0.999	0.000
H16.9 Keratitis, unspecified	0.001	0.999	0.000
H15.0 Scleritis	0.001	0.999	0.000
H16.3 Interstitial and deep keratitis	0.001	0.999	0.000
H18 Other disorders of cornea	0.001	0.999	0.000
H15.8 Other disorders of sclera	0.001	0.999	0.000
H15.1 Episcleritis	0.001	0.999	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.000	0.999	0.001
J69.1 Pneumonitis due to oils and essences	0.000	0.999	0.001
K91.0 Vomiting following gastro-intestinal surgery	0.001	0.999	0.000
H42 Glaucoma in diseases classified elsewhere	0.000	0.999	0.001
H52.1 Myopia	0.000	0.999	0.001
J69.8 Pneumonitis due to other solids and liquids	0.000	0.999	0.001
Z02.8 Other examinations for administrative purposes	0.001	0.999	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.999	0.001
D37.7 Other digestive organs	0.001	0.999	0.000
F43.2 Adjustment disorders	0.001	0.999	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.001	0.999	0.000
H18.2 Other corneal oedema	0.001	0.999	0.000
K90.9 Intestinal malabsorption, unspecified	0.001	0.999	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.001	0.999	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.001	0.999	0.000
H18.3 Changes in corneal membranes	0.001	0.999	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.001	0.999	0.000
K90.3 Pancreatic steatorrhoea	0.001	0.999	0.001
K90.2 Blind loop syndrome, not elsewhere classified	0.001	0.999	0.001
K90.1 Tropical sprue	0.001	0.999	0.001
K93 Disorders of other digestive organs in diseases classified elsewhere	0.001	0.999	0.000
H18.7 Other corneal deformities	0.001	0.999	0.000
H18.6 Keratoconus	0.001	0.999	0.000
K90.8 Other intestinal malabsorption	0.001	0.999	0.001
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.001	0.999	0.000
R44.1 Visual hallucinations	0.001	0.999	0.000
V18.0 Driver injured in nontraffic accident	0.001	0.999	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.999	0.001
H18.1 Bullous keratopathy	0.001	0.999	0.000
R44.2 Other hallucinations	0.001	0.999	0.000
H18.9 Disorder of cornea, unspecified	0.001	0.999	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.000	0.999	0.001
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.000	0.999	0.001
T18.1 Foreign body in oesophagus	0.000	0.999	0.001
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.001	0.999	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.999	0.000
H18.0 Corneal pigmentations and deposits	0.001	0.999	0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.000	0.999	0.001
O14.9 Preeclampsia, unspecified	0.001	0.999	0.000
R44.0 Auditory hallucinations	0.001	0.999	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.001	0.999	0.000
K91.4 Colostomy and enterostomy malfunction	0.001	0.999	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.999	0.001
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.999	0.001
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.001	0.999	0.000
K93.1 Megacolon in Chagas' disease	0.001	0.999	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.001	0.999	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.999	0.001
R63.8 Other symptoms and signs concerning food and fluid intake	0.001	0.999	0.000
C20 Malignant neoplasm of rectum	0.000	0.999	0.001
I38 Endocarditis, valve unspecified	0.000	0.999	0.001
M41.99 Scoliosis, unspecified (Site unspecified)	0.001	0.999	0.000
H18.8 Other specified disorders of cornea	0.001	0.999	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.001	0.999	0.000
H18.4 Corneal degeneration	0.001	0.999	0.000
H52.0 Hypermetropia	0.000	0.999	0.001
I27.2 Other secondary pulmonary hypertension	0.000	0.999	0.001
L98.4 Chronic ulcer of skin, not elsewhere classified	0.000	0.999	0.001
G35 Multiple sclerosis	0.000	0.999	0.001
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.999	0.001
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.001	0.999	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.001	0.999	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.999	0.001
S52.80 Fracture of other parts of forearm (closed)	0.000	0.999	0.001
C43.4 Malignant melanoma of scalp and neck	0.000	0.999	0.001
H18.5 Hereditary corneal dystrophies	0.001	0.999	0.000
M41.9 Scoliosis, unspecified	0.001	0.999	0.000
S51.9 Open wound of forearm, part unspecified	0.000	0.999	0.001
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.001	0.999	0.000
L30.9 Dermatitis, unspecified	0.001	0.999	0.000
S51.8 Open wound of other parts of forearm	0.000	0.999	0.001
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.001	0.999	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.001	0.999	0.000
C71.3 Parietal lobe	0.000	0.999	0.001
K11.5 Sialolithiasis	0.000	0.999	0.001
R44.3 Hallucinations, unspecified	0.001	0.999	0.000
S51.7 Multiple open wounds of forearm	0.000	0.999	0.001
T93.9 Sequelae of unspecified injury of lower limb	0.000	0.999	0.001
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.999	0.001
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.999	0.001
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.999	0.001
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.999	0.001
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.001	0.999	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.001	0.999	0.000
R63.0 Anorexia	0.001	0.999	0.000
T78.3 Angioneurotic oedema	0.000	0.999	0.001
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.001	0.999	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.001	0.999	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.999	0.001
C71.9 Brain, unspecified	0.000	0.999	0.001
D39.1 Ovary	0.001	0.999	0.000
L40.9 Psoriasis, unspecified	0.000	0.999	0.001
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.000	0.999	0.001
M41.94 Scoliosis, unspecified (Thoracic region)	0.001	0.999	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.999	0.001
H52.3 Anisometropia and aniseikonia	0.000	0.999	0.001
I95.2 Hypotension due to drugs	0.001	0.999	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.999	0.001
T93.1 Sequelae of fracture of femur	0.000	0.999	0.001
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.999	0.001
L98.7 Excessive and redundant skin and subcutaneous tissue	0.000	0.999	0.001
L98.6 Other infiltrative disorders of skin and subcutaneous tissue	0.000	0.999	0.001
L98.3 Eosinophilic cellulitis [Wells]	0.000	0.999	0.001
L98.2 Febrile neutrophilic dermatosis [Sweet]	0.000	0.999	0.001
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.999	0.001
R54 Senility	0.001	0.999	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.001	0.999	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.001	0.999	0.000
D73.1 Hypersplenism	0.000	0.999	0.001
H57.1 Ocular pain	0.000	0.999	0.001
I20.8 Other forms of angina pectoris	0.001	0.999	0.000
J03.9 Acute tonsillitis, unspecified	0.001	0.999	0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.001	0.999	0.000
L98.1 Factitial dermatitis	0.000	0.999	0.001
N95.8 Other specified menopausal and perimenopausal disorders	0.001	0.999	0.000
Q23.1 Congenital insufficiency of aortic valve	0.001	0.999	0.000
T79.7 Traumatic subcutaneous emphysema	0.001	0.999	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.999	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.999	0.001
F10.7 Residual and late-onset psychotic disorder	0.001	0.999	0.000
F10.6 Amnesic syndrome	0.001	0.999	0.000
K92.1 Melaena	0.001	0.999	0.000
O26.8 Other specified pregnancy-related conditions	0.000	0.999	0.001
C43 Malignant melanoma of skin	0.000	0.999	0.001
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.001	0.999	0.000
C43.8 Overlapping malignant melanoma of skin	0.000	0.999	0.001
D25.1 Intramural leiomyoma of uterus	0.001	0.999	0.000
F10.9 Unspecified mental and behavioural disorder	0.001	0.999	0.000
L98.5 Mucinosis of skin	0.000	0.999	0.001
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.001	0.999	0.000
C43.0 Malignant melanoma of lip	0.000	0.999	0.001
D41.4 Bladder	0.000	0.999	0.001
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.999	0.001
F10.4 Withdrawal state with delirium	0.001	0.999	0.000
F10.2 Dependence syndrome	0.001	0.999	0.000
H52.6 Other disorders of refraction	0.000	0.999	0.001
H52.5 Disorders of accommodation	0.000	0.999	0.001
H52.4 Presbyopia	0.000	0.999	0.001
K22.1 Ulcer of oesophagus	0.000	0.999	0.001
K59.4 Anal spasm	0.001	0.999	0.000
L30.8 Other specified dermatitis	0.001	0.999	0.000
M23.8 Other internal derangements of knee	0.001	0.999	0.000
T79.6 Traumatic ischaemia of muscle	0.001	0.999	0.000
D70 Agranulocytosis	0.001	0.999	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.001	0.999	0.000
H52 Disorders of refraction and accommodation	0.000	0.999	0.001
M23.87 Other internal derangements of knee (Capsular ligament)	0.001	0.999	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.001	0.999	0.000
C71.5 Cerebral ventricle	0.000	0.999	0.001
D73.8 Other diseases of spleen	0.000	0.999	0.001
D73.2 Chronic congestive splenomegaly	0.000	0.999	0.001
F10.8 Other mental and behavioural disorders	0.001	0.999	0.000
J98.3 Compensatory emphysema	0.001	0.999	0.000
N87.0 Mild cervical dysplasia	0.001	0.999	0.000
O14.1 Severe preeclampsia	0.001	0.999	0.000
O82.0 Delivery by elective Caesarean section	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations