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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6455
log Bayes Factor = 1.58465
Chromosome 6   position 32,006,896  (GRCh37) Explore rs6455 on Ensembl!
Variant rs6455 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.041 0.959
D50-D53 Nutritional anaemias
0.000 0.042 0.958
D50 Iron deficiency anaemia
0.000 0.044 0.956
# Top node
0.000 0.045 0.955
Chapter XI Diseases of the digestive system
0.000 0.063 0.937
D50.9 Iron deficiency anaemia, unspecified
0.000 0.066 0.934
K90-K93 Other diseases of the digestive system
0.000 0.069 0.931
Chapter XIV Diseases of the genitourinary system
0.000 0.069 0.931
K90 Intestinal malabsorption
0.000 0.070 0.930
K90.0 Coeliac disease
0.000 0.071 0.929
D50.8 Other iron deficiency anaemias
0.000 0.072 0.928
Chapter I Certain infectious and parasitic diseases
0.000 0.078 0.922
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.079 0.921
K50-K52 Noninfective enteritis and colitis
0.000 0.079 0.921
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.087 0.913
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.088 0.912
B95-B98 Bacterial, viral and other infectious agents
0.000 0.094 0.906
K50 Crohn's disease [regional enteritis]
0.000 0.099 0.901
L03 Cellulitis
0.000 0.102 0.898
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.000 0.103 0.897
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.000 0.108 0.892
E65-E68 Obesity and other hyperalimentation
0.000 0.110 0.890
N80-N98 Noninflammatory disorders of female genital tract
0.000 0.116 0.884
L03.1 Cellulitis of other parts of limb
0.000 0.124 0.876
E66 Obesity
0.000 0.126 0.874
E66.9 Obesity, unspecified
0.000 0.132 0.868
B25-B34 Other viral diseases
0.000 0.136 0.864
N70-N77 Inflammatory diseases of female pelvic organs
0.000 0.140 0.860
N10-N16 Renal tubulo-interstitial diseases
0.000 0.144 0.856
E50-E64 Other nutritional deficiencies
0.000 0.155 0.845
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.156 0.844
K50.9 Crohn's disease, unspecified
0.000 0.169 0.831
N92 Excessive, frequent and irregular menstruation
0.000 0.170 0.830
D80-D89 Certain disorders involving the immune mechanism
0.000 0.170 0.830
N80 Endometriosis
0.000 0.173 0.827
D51 Vitamin B12 deficiency anaemia
0.000 0.176 0.823
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.000 0.177 0.823
B34 Viral infection of unspecified site
0.000 0.178 0.822
N88 Other noninflammatory disorders of cervix uteri
0.000 0.184 0.816
L03.3 Cellulitis of trunk
0.000 0.188 0.812
N92.0 Excessive and frequent menstruation with regular cycle
0.000 0.193 0.807
N73 Other female pelvic inflammatory diseases
0.000 0.196 0.804
Chapter XV Pregnancy, childbirth and the puerperium
0.000 0.204 0.796
B34.9 Viral infection, unspecified
0.000 0.207 0.793
J45.9 Asthma, unspecified
0.000 0.208 0.792
K50.0 Crohn's disease of small intestine
0.000 0.208 0.792
Chapter X Diseases of the respiratory system
0.000 0.209 0.791
J45 Asthma
0.000 0.212 0.788
K52 Other non-infective gastro-enteritis and colitis
0.000 0.214 0.786
N60-N64 Disorders of breast
0.000 0.218 0.782
D60-D64 Aplastic and other anaemias
0.000 0.220 0.780
J40-J47 Chronic lower respiratory diseases
0.000 0.226 0.773
L50-L54 Urticaria and erythema
0.000 0.228 0.772
N73.6 Female pelvic peritoneal adhesions
0.000 0.233 0.767
K50.1 Crohn's disease of large intestine
0.000 0.233 0.767
E53 Deficiency of other B group vitamins
0.000 0.241 0.759
D86 Sarcoidosis
0.000 0.252 0.748
L05 Pilonidal cyst
0.000 0.259 0.741
N88.2 Stricture and stenosis of cervix uteri
0.000 0.266 0.734
N80.1 Endometriosis of ovary
0.000 0.273 0.727
D52 Folate deficiency anaemia
0.000 0.274 0.726
J45.0 Predominantly allergic asthma
0.000 0.276 0.724
D69 Purpura and other haemorrhagic conditions
0.000 0.279 0.721
K90.9 Intestinal malabsorption, unspecified
0.000 0.280 0.720
L03.9 Cellulitis, unspecified
0.000 0.280 0.720
D64 Other anaemias
0.000 0.281 0.719
L20-L30 Dermatitis and eczema
0.000 0.287 0.713
Chapter XXII Codes for special purposes
0.000 0.288 0.712
Chapter XXI Factors influencing health status and contact with health services
0.000 0.289 0.711
L08 Other local infections of skin and subcutaneous tissue
0.000 0.289 0.711
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.000 0.290 0.710
N72 Inflammatory disease of cervix uteri
0.000 0.293 0.707
Z70-Z76 Persons encountering health services in other circumstances
0.000 0.294 0.706
A80-A89 Viral infections of the central nervous system
0.000 0.296 0.704
N88.8 Other specified noninflammatory disorders of cervix uteri
0.000 0.296 0.704
Z72.0 Tobacco use
0.000 0.296 0.704
Chapter V Mental and behavioural disorders
0.000 0.296 0.704
Z72 Problems related to lifestyle
0.000 0.298 0.702
E55 Vitamin D deficiency
0.000 0.301 0.699
E53.8 Deficiency of other specified B group vitamins
0.000 0.303 0.697
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.303 0.697
K70-K77 Diseases of liver
0.000 0.304 0.696
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.306 0.694
Chapter VII Diseases of the eye and adnexa
0.000 0.310 0.690
D55-D59 Haemolytic anaemias
0.000 0.313 0.687
D53 Other nutritional anaemias
0.000 0.313 0.687
D50.1 Sideropenic dysphagia
0.000 0.315 0.685
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.315 0.685
D68 Other coagulation defects
0.000 0.315 0.685
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.316 0.684
N25-N29 Other disorders of kidney and ureter
0.000 0.318 0.682
K35-K38 Diseases of appendix
0.000 0.319 0.681
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.320 0.680
D64.9 Anaemia, unspecified
0.000 0.324 0.676
N80.9 Endometriosis, unspecified
0.000 0.325 0.675
B99-B99 Other infectious diseases
0.000 0.326 0.674
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.000 0.329 0.671
K50.8 Other Crohn's disease
0.000 0.330 0.670
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.330 0.670
N87 Dysplasia of cervix uteri
0.000 0.330 0.670
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.332 0.668
N94.6 Dysmenorrhoea, unspecified
0.000 0.333 0.667
K90.8 Other intestinal malabsorption
0.000 0.333 0.667
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.333 0.667
K90.3 Pancreatic steatorrhoea
0.000 0.333 0.667
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.333 0.667
K90.1 Tropical sprue
0.000 0.333 0.667
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.000 0.333 0.667
N80.0 Endometriosis of uterus
0.000 0.336 0.664
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.338 0.662
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.339 0.661
B65-B83 Helminthiases
0.000 0.339 0.661
B50-B64 Protozoal diseases
0.000 0.339 0.661
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.339 0.661
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.339 0.661
A75-A79 Rickettsioses
0.000 0.339 0.661
A70-A74 Other diseases caused by chlamydiae
0.000 0.339 0.661
A65-A69 Other spirochaetal diseases
0.000 0.339 0.661
A20-A28 Certain zoonotic bacterial diseases
0.000 0.339 0.661
A15-A19 Tuberculosis
0.000 0.339 0.661
L10-L14 Bullous disorders
0.000 0.339 0.660
K65-K67 Diseases of peritoneum
0.000 0.341 0.659
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.343 0.657
N62 Hypertrophy of breast
0.000 0.344 0.656
L04 Acute lymphadenitis
0.000 0.346 0.654
L01 Impetigo
0.000 0.346 0.654
L00 Staphylococcal scalded skin syndrome
0.000 0.346 0.654
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.346 0.654
O20-O29 Other maternal disorders predominantly related to pregnancy
0.000 0.347 0.653
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.347 0.653
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.348 0.652
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.000 0.348 0.651
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.000 0.351 0.649
D86.9 Sarcoidosis, unspecified
0.000 0.351 0.649
N92.4 Excessive bleeding in the premenopausal period
0.000 0.352 0.647
H53-H54 Visual disturbances and blindness
0.000 0.353 0.647
N89 Other noninflammatory disorders of vagina
0.000 0.354 0.646
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.000 0.357 0.643
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.000 0.357 0.643
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.000 0.357 0.643
B97 Viral agents as the cause of diseases classified to other chapters
0.000 0.358 0.642
N86 Erosion and ectropion of cervix uteri
0.000 0.359 0.640
J95-J99 Other diseases of the respiratory system
0.000 0.361 0.639
K51 Ulcerative colitis
0.000 0.361 0.639
E67 Other hyperalimentation
0.000 0.362 0.638
E68 Sequelae of hyperalimentation
0.000 0.362 0.638
E65 Localised adiposity
0.000 0.362 0.638
E00-E07 Disorders of thyroid gland
0.000 0.365 0.635
L03.8 Cellulitis of other sites
0.000 0.366 0.634
N98 Complications associated with artificial fertilisation
0.000 0.366 0.634
N91 Absent, scanty and rare menstruation
0.000 0.366 0.634
N82 Fistulae involving female genital tract
0.000 0.366 0.634
N96 Habitual aborter
0.000 0.366 0.634
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.000 0.366 0.634
L50 Urticaria
0.000 0.368 0.632
N80.8 Other endometriosis
0.000 0.373 0.627
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.373 0.627
E66.1 Drug-induced obesity
0.000 0.373 0.627
E66.0 Obesity due to excess calories
0.000 0.373 0.627
N75 Diseases of Bartholin's gland
0.000 0.375 0.625
E10-E14 Diabetes mellitus
0.000 0.375 0.625
N00-N08 Glomerular diseases
0.000 0.378 0.622
O48 Prolonged pregnancy
0.000 0.378 0.622
L30 Other dermatitis
0.000 0.378 0.622
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.000 0.378 0.622
E61 Deficiency of other nutrient elements
0.000 0.379 0.621
D86.0 Sarcoidosis of lung
0.000 0.380 0.620
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.000 0.380 0.620
N70 Salpingitis and oophoritis
0.000 0.380 0.620
B33 Other viral diseases, not elsewhere classified
0.000 0.381 0.619
B30 Viral conjunctivitis
0.000 0.381 0.619
B27 Infectious mononucleosis
0.000 0.381 0.619
B26 Mumps
0.000 0.381 0.619
B25 Cytomegaloviral disease
0.000 0.381 0.619
B35-B49 Mycoses
0.000 0.381 0.619
E20-E35 Disorders of other endocrine glands
0.000 0.382 0.618
D69.6 Thrombocytopenia, unspecified
0.000 0.382 0.618
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.000 0.383 0.616
N71 Inflammatory disease of uterus, except cervix
0.000 0.383 0.616
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.000 0.384 0.616
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.385 0.615
N85 Other noninflammatory disorders of uterus, except cervix
0.000 0.386 0.614
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.000 0.386 0.614
N15 Other renal tubulo-interstitial diseases
0.000 0.386 0.614
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.000 0.386 0.614
N11 Chronic tubulo-interstitial nephritis
0.000 0.386 0.614
N64 Other disorders of breast
0.000 0.388 0.612
N99-N99 Other disorders of the genitourinary system
0.000 0.388 0.612
N60 Benign mammary dysplasia
0.000 0.388 0.612
N17-N19 Renal failure
0.000 0.390 0.610
H02 Other disorders of eyelid
0.000 0.390 0.610
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.394 0.606
E63 Other nutritional deficiencies
0.000 0.394 0.606
E56 Other vitamin deficiencies
0.000 0.394 0.606
E51 Thiamine deficiency
0.000 0.394 0.606
E50 Vitamin A deficiency
0.000 0.394 0.606
E60 Dietary zinc deficiency
0.000 0.394 0.606
E59 Dietary selenium deficiency
0.000 0.394 0.606
E58 Dietary calcium deficiency
0.000 0.394 0.606
E54 Ascorbic acid deficiency
0.000 0.394 0.606
E52 Niacin deficiency [pellagra]
0.000 0.394 0.606
N93 Other abnormal uterine and vaginal bleeding
0.000 0.394 0.606
D67 Hereditary factor IX deficiency
0.000 0.395 0.605
D66 Hereditary factor VIII deficiency
0.000 0.395 0.605
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.395 0.605
N92.5 Other specified irregular menstruation
0.000 0.395 0.605
D61 Other aplastic anaemias
0.000 0.395 0.605
L53 Other erythematous conditions
0.000 0.397 0.603
L05.9 Pilonidal cyst without abscess
0.000 0.404 0.596
N92.2 Excessive menstruation at puberty
0.000 0.405 0.595
D84 Other immunodeficiencies
0.000 0.405 0.595
D83 Common variable immunodeficiency
0.000 0.405 0.595
D82 Immunodeficiency associated with other major defects
0.000 0.405 0.595
D81 Combined immunodeficiencies
0.000 0.405 0.595
D80 Immunodeficiency with predominantly antibody defects
0.000 0.405 0.595
E55.9 Vitamin D deficiency, unspecified
0.000 0.405 0.595
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.000 0.406 0.594
N80.6 Endometriosis in cutaneous scar
0.000 0.407 0.593
N80.5 Endometriosis of intestine
0.000 0.407 0.593
N80.4 Endometriosis of rectovaginal septum and vagina
0.000 0.407 0.593
N80.2 Endometriosis of Fallopian tube
0.000 0.407 0.593
F40-F48 Neurotic, stress-related and somatoform disorders
0.000 0.407 0.593
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.000 0.409 0.591
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.409 0.590
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.409 0.590
D51.2 Transcobalamin II deficiency
0.000 0.409 0.590
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.409 0.590
B34.8 Other viral infections of unspecified site
0.000 0.410 0.590
B34.4 Papovirus infection, unspecified
0.000 0.410 0.590
B34.3 Parvovirus infection, unspecified
0.000 0.410 0.590
B34.2 Coronavirus infection, unspecified
0.000 0.410 0.590
B34.1 Enterovirus infection, unspecified
0.000 0.410 0.590
B34.0 Adenovirus infection, unspecified
0.000 0.410 0.590
B15-B19 Viral hepatitis
0.000 0.412 0.587
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.414 0.586
N88.4 Hypertrophic elongation of cervix uteri
0.000 0.415 0.585
N88.3 Incompetence of cervix uteri
0.000 0.415 0.585
N88.1 Old laceration of cervix uteri
0.000 0.415 0.585
N88.0 Leukoplakia of cervix uteri
0.000 0.415 0.585
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.000 0.415 0.585
N92.3 Ovulation bleeding
0.000 0.418 0.582
N80.3 Endometriosis of pelvic peritoneum
0.000 0.418 0.582
O80-O84 Delivery
0.000 0.418 0.582
N90 Other noninflammatory disorders of vulva and perineum
0.000 0.419 0.581
Chapter VIII Diseases of the ear and mastoid process
0.000 0.419 0.581
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.000 0.419 0.580
H02.8 Other specified disorders of eyelid
0.000 0.420 0.580
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.423 0.577
O94-O99 Other obstetric conditions, not elsewhere classified
0.000 0.423 0.577
N73.8 Other specified female pelvic inflammatory diseases
0.000 0.423 0.577
N73.5 Female pelvic peritonitis, unspecified
0.000 0.423 0.577
N73.4 Female chronic pelvic peritonitis
0.000 0.423 0.577
N73.3 Female acute pelvic peritonitis
0.000 0.423 0.577
N73.2 Unspecified parametritis and pelvic cellulitis
0.000 0.423 0.577
N73.1 Chronic parametritis and pelvic cellulitis
0.000 0.423 0.577
N73.0 Acute parametritis and pelvic cellulitis
0.000 0.423 0.577
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.424 0.576
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.426 0.574
N84 Polyp of female genital tract
0.000 0.427 0.573
K37 Unspecified appendicitis
0.000 0.427 0.573
H54 Blindness and low vision
0.000 0.427 0.573
O85-O92 Complications predominantly related to the puerperium
0.000 0.429 0.571
N76 Other inflammation of vagina and vulva
0.000 0.429 0.571
H53 Visual disturbances
0.000 0.430 0.570
N61 Inflammatory disorders of breast
0.000 0.431 0.569
O20 Haemorrhage in early pregnancy
0.000 0.431 0.569
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.431 0.569
J60-J70 Lung diseases due to external agents
0.000 0.432 0.568
E40-E46 Malnutrition
0.000 0.434 0.566
J45.8 Mixed asthma
0.000 0.435 0.565
J45.1 Nonallergic asthma
0.000 0.435 0.565
N92.6 Irregular menstruation, unspecified
0.000 0.436 0.564
K52.3 Indeterminate colitis
0.000 0.436 0.563
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.436 0.563
L05.0 Pilonidal cyst with abscess
0.000 0.437 0.563
H00 Hordeolum and chalazion
0.000 0.438 0.562
K52.1 Toxic gastro-enteritis and colitis
0.000 0.438 0.562
N73.9 Female pelvic inflammatory disease, unspecified
0.000 0.439 0.561
K70 Alcoholic liver disease
0.000 0.439 0.561
N20-N23 Urolithiasis
0.000 0.439 0.560
D52.9 Folate deficiency anaemia, unspecified
0.000 0.440 0.560
J46 Status asthmaticus
0.000 0.440 0.560
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.441 0.559
N13 Obstructive and reflux uropathy
0.000 0.441 0.559
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.441 0.559
J43 Emphysema
0.000 0.443 0.557
J86 Pyothorax
0.000 0.444 0.556
L40-L45 Papulosquamous disorders
0.001 0.445 0.554
J41 Simple and mucopurulent chronic bronchitis
0.000 0.445 0.554
D68.2 Hereditary deficiency of other clotting factors
0.000 0.445 0.555
L54 Erythema in diseases classified elsewhere
0.000 0.447 0.553
L51 Erythema multiforme
0.000 0.447 0.553
L52 Erythema nodosum
0.000 0.447 0.553
N30-N39 Other diseases of urinary system
0.000 0.447 0.553
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.447 0.553
L30.9 Dermatitis, unspecified
0.000 0.448 0.552
N87.0 Mild cervical dysplasia
0.000 0.449 0.550
L03.2 Cellulitis of face
0.000 0.450 0.550
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.000 0.451 0.549
A87 Viral meningitis
0.000 0.451 0.549
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.000 0.454 0.546
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.455 0.545
E53.9 Vitamin B deficiency, unspecified
0.000 0.456 0.544
E53.1 Pyridoxine deficiency
0.000 0.456 0.544
E53.0 Riboflavin deficiency
0.000 0.456 0.544
N97 Female infertility
0.000 0.458 0.542
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.458 0.542
K65 Peritonitis
0.000 0.458 0.542
O20.0 Threatened abortion
0.000 0.459 0.541
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.000 0.460 0.540
K72 Hepatic failure, not elsewhere classified
0.000 0.461 0.539
N94.3 Premenstrual tension syndrome
0.000 0.461 0.539
L03.0 Cellulitis of finger and toe
0.000 0.463 0.536
J84 Other interstitial pulmonary diseases
0.000 0.464 0.536
D86.8 Sarcoidosis of other and combined sites
0.000 0.464 0.536
D86.3 Sarcoidosis of skin
0.000 0.464 0.536
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.464 0.536
D86.1 Sarcoidosis of lymph nodes
0.000 0.464 0.536
N10 Acute tubulo-interstitial nephritis
0.000 0.465 0.535
N88.9 Noninflammatory disorder of cervix uteri, unspecified
0.000 0.465 0.534
L50.9 Urticaria, unspecified
0.000 0.468 0.532
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.470 0.530
L27 Dermatitis due to substances taken internally
0.000 0.470 0.530
F00-F09 Organic, including symptomatic, mental disorders
0.000 0.470 0.530
K08 Other disorders of teeth and supporting structures
0.000 0.471 0.529
O30 Multiple gestation
0.000 0.471 0.529
N95 Menopausal and other perimenopausal disorders
0.000 0.473 0.527
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.000 0.474 0.526
F41 Other anxiety disorders
0.000 0.478 0.522
D52.8 Other folate deficiency anaemias
0.000 0.479 0.521
D52.1 Drug-induced folate deficiency anaemia
0.000 0.479 0.521
D52.0 Dietary folate deficiency anaemia
0.000 0.479 0.521
N26 Unspecified contracted kidney
0.000 0.480 0.520
K83 Other diseases of biliary tract
0.000 0.480 0.520
K92 Other diseases of digestive system
0.000 0.481 0.519
Z73 Problems related to life-management difficulty
0.000 0.481 0.519
D69.9 Haemorrhagic condition, unspecified
0.000 0.483 0.517
D69.8 Other specified haemorrhagic conditions
0.000 0.483 0.517
D69.4 Other primary thrombocytopenia
0.000 0.483 0.517
D69.2 Other nonthrombocytopenic purpura
0.000 0.483 0.517
D69.1 Qualitative platelet defects
0.000 0.483 0.517
D69.0 Allergic purpura
0.000 0.483 0.517
O46 Antepartum haemorrhage, not elsewhere classified
0.000 0.483 0.517
H02.9 Disorder of eyelid, unspecified
0.000 0.483 0.516
O00-O08 Pregnancy with abortive outcome
0.000 0.484 0.516
D64.8 Other specified anaemias
0.000 0.484 0.516
D64.4 Congenital dyserythropoietic anaemia
0.000 0.484 0.516
D64.3 Other sideroblastic anaemias
0.000 0.484 0.516
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.484 0.516
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.484 0.516
D64.0 Hereditary sideroblastic anaemia
0.000 0.484 0.516
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.484 0.516
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.484 0.515
F60-F69 Disorders of adult personality and behaviour
0.000 0.485 0.515
E14 Unspecified diabetes mellitus
0.000 0.485 0.515
L90 Atrophic disorders of skin
0.000 0.486 0.514
D68.5 Primary Thrombophilia
0.000 0.487 0.513
N85.0 Endometrial glandular hyperplasia
0.000 0.487 0.513
L25 Unspecified contact dermatitis
0.000 0.489 0.511
L24 Irritant contact dermatitis
0.000 0.489 0.511
L23 Allergic contact dermatitis
0.000 0.489 0.511
L21 Seborrhoeic dermatitis
0.000 0.489 0.511
L20 Atopic dermatitis
0.000 0.489 0.511
L26 Exfoliative dermatitis
0.000 0.489 0.511
L22 Diaper [napkin] dermatitis
0.000 0.489 0.511
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.490 0.510
L08.1 Erythrasma
0.000 0.490 0.510
L08.0 Pyoderma
0.000 0.490 0.510
D68.8 Other specified coagulation defects
0.000 0.490 0.510
N89.8 Other specified noninflammatory disorders of vagina
0.000 0.490 0.509
N94.5 Secondary dysmenorrhoea
0.000 0.491 0.509
N94.2 Vaginismus
0.000 0.491 0.509
N94.0 Mittelschmerz
0.000 0.491 0.509
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.492 0.508
Z76 Persons encountering health services in other circumstances
0.000 0.493 0.506
Z70 Counselling related to sexual attitude, behaviour and orientation
0.000 0.493 0.506
H53.8 Other visual disturbances
0.000 0.494 0.506
A88 Other viral infections of central nervous system, not elsewhere classified
0.000 0.495 0.505
A85 Other viral encephalitis, not elsewhere classified
0.000 0.495 0.505
A84 Tick-borne viral encephalitis
0.000 0.495 0.505
A83 Mosquito-borne viral encephalitis
0.000 0.495 0.505
A82 Rabies
0.000 0.495 0.505
A81 Atypical virus infections of central nervous system
0.000 0.495 0.505
A80 Acute poliomyelitis
0.000 0.495 0.505
A91 Dengue haemorrhagic fever
0.000 0.495 0.505
A90 Dengue fever [classical dengue]
0.000 0.495 0.505
A89 Unspecified viral infection of central nervous system
0.000 0.495 0.505
A86 Unspecified viral encephalitis
0.000 0.495 0.505
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.495 0.505
F80-F89 Disorders of psychological development
0.000 0.495 0.505
F70-F79 Mental retardation
0.000 0.495 0.505
H10-H13 Disorders of conjunctiva
0.000 0.496 0.504
J80 Adult respiratory distress syndrome
0.000 0.496 0.504
K51.9 Ulcerative colitis, unspecified
0.000 0.497 0.503
Z72.9 Problem related to lifestyle, unspecified
0.000 0.497 0.503
Z72.8 Other problems related to lifestyle
0.000 0.497 0.503
Z72.6 Gambling and betting
0.000 0.497 0.503
Z72.5 High-risk sexual behaviour
0.000 0.497 0.503
Z72.4 Inappropriate diet and eating habits
0.000 0.497 0.503
Z72.3 Lack of physical exercise
0.000 0.497 0.503
D69.5 Secondary thrombocytopenia
0.000 0.497 0.502
K38 Other diseases of appendix
0.000 0.498 0.502
K91.4 Colostomy and enterostomy malfunction
0.000 0.498 0.501
E55.0 Rickets, active
0.000 0.499 0.501
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.000 0.499 0.501
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.000 0.500 0.500
Z74 Problems related to care-provider dependency
0.000 0.500 0.499
F99-F99 Unspecified mental disorder
0.000 0.501 0.499
K77 Liver disorders in diseases classified elsewhere
0.000 0.501 0.499
K73 Chronic hepatitis, not elsewhere classified
0.000 0.501 0.499
K71 Toxic liver disease
0.000 0.501 0.499
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.501 0.499
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.000 0.502 0.498
N64.9 Disorder of breast, unspecified
0.000 0.502 0.498
H00.1 Chalazion
0.000 0.502 0.498
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.000 0.503 0.497
B99 Other and unspecified infectious diseases
0.000 0.503 0.497
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.503 0.497
O35 Maternal care for known or suspected foetal abnormality and damage
0.000 0.505 0.495
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.505 0.495
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.000 0.506 0.494
H54.7 Unspecified visual loss
0.000 0.507 0.493
D59 Acquired haemolytic anaemia
0.000 0.507 0.493
D58 Other hereditary haemolytic anaemias
0.000 0.507 0.493
D57 Sickle-cell disorders
0.000 0.507 0.493
D56 Thalassaemia
0.000 0.507 0.493
D55 Anaemia due to enzyme disorders
0.000 0.507 0.493
D53.9 Nutritional anaemia, unspecified
0.000 0.507 0.492
D53.8 Other specified nutritional anaemias
0.000 0.507 0.492
D53.2 Scorbutic anaemia
0.000 0.507 0.492
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.507 0.492
D53.0 Protein deficiency anaemia
0.000 0.507 0.492
K51.2 Ulcerative (chronic) proctitis
0.000 0.508 0.492
K02 Dental caries
0.000 0.508 0.492
Z71.3 Dietary counselling and surveillance
0.000 0.508 0.492
P90-P96 Other disorders originating in the perinatal period
0.000 0.509 0.491
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.000 0.509 0.491
P75-P78 Digestive system disorders of fetus and newborn
0.000 0.509 0.491
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.000 0.509 0.491
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.000 0.509 0.491
P35-P39 Infections specific to the perinatal period
0.000 0.509 0.491
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.000 0.509 0.491
P10-P15 Birth trauma
0.000 0.509 0.491
P05-P08 Disorders related to length of gestation and fetal growth
0.000 0.509 0.491
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.000 0.509 0.491
D68.6 Other Thrombophilia
0.000 0.509 0.491
D68.4 Acquired coagulation factor deficiency
0.000 0.509 0.491
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.509 0.491
D68.1 Hereditary factor XI deficiency
0.000 0.509 0.491
D68.0 Von Willebrand's disease
0.000 0.509 0.491
L28 Lichen simplex chronicus and prurigo
0.000 0.510 0.489
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.511 0.489
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.000 0.511 0.489
N27 Small kidney of unknown cause
0.000 0.511 0.489
N25 Disorders resulting from impaired renal tubular function
0.000 0.511 0.489
K36 Other appendicitis
0.000 0.511 0.488
N60.2 Fibroadenosis of breast
0.000 0.512 0.487
H90-H95 Other disorders of ear
0.000 0.513 0.487
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.513 0.487
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.000 0.513 0.487
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.513 0.487
K81 Cholecystitis
0.000 0.513 0.487
O40 Polyhydramnios
0.000 0.514 0.486
F41.2 Mixed anxiety and depressive disorder
0.000 0.514 0.486
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.514 0.485
J86.9 Pyothorax without fistula
0.000 0.515 0.485
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.516 0.484
H53.1 Subjective visual disturbances
0.000 0.517 0.483
L53.9 Erythematous condition, unspecified
0.000 0.517 0.483
N30 Cystitis
0.000 0.517 0.483
E27 Other disorders of adrenal gland
0.000 0.518 0.482
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.000 0.519 0.481
A60 Anogenital herpesviral [herpes simplex] infections
0.000 0.520 0.480
A59 Trichomoniasis
0.000 0.520 0.480
A56 Other sexually transmitted chlamydial diseases
0.000 0.520 0.480
A54 Gonococcal infection
0.000 0.520 0.480
A53 Other and unspecified syphilis
0.000 0.520 0.480
A52 Late syphilis
0.000 0.520 0.480
A51 Early syphilis
0.000 0.520 0.480
A50 Congenital syphilis
0.000 0.520 0.480
A64 Unspecified sexually transmitted disease
0.000 0.520 0.480
A58 Granuloma inguinale
0.000 0.520 0.480
A57 Chancroid
0.000 0.520 0.480
A55 Chlamydial lymphogranuloma (venereum)
0.000 0.520 0.480
N87.2 Severe cervical dysplasia, not elsewhere classified
0.000 0.520 0.480
N89.5 Stricture and atresia of vagina
0.000 0.520 0.480
D61.9 Aplastic anaemia, unspecified
0.000 0.520 0.480
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.520 0.479
K75 Other inflammatory liver diseases
0.000 0.521 0.479
L90.0 Lichen sclerosus et atrophicus
0.000 0.521 0.479
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.521 0.479
K93.1 Megacolon in Chagas' disease
0.000 0.521 0.479
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.521 0.479
O45 Premature separation of placenta [abruptio placentae]
0.000 0.522 0.478
O44 Placenta praevia
0.000 0.522 0.478
O43 Placental disorders
0.000 0.522 0.478
O33 Maternal care for known or suspected disproportion
0.000 0.522 0.478
O31 Complications specific to multiple gestation
0.000 0.522 0.478
K06 Other disorders of gingiva and edentulous alveolar ridge
0.000 0.524 0.476
K74 Fibrosis and cirrhosis of liver
0.000 0.524 0.476

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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