TreeWAS – Variant ID: rs6477694

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E21.0 Primary hyperparathyroidism	0.065	0.935	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.061	0.939	0.000
E21.3 Hyperparathyroidism, unspecified	0.060	0.940	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.055	0.945	0.000
E21.2 Other hyperparathyroidism	0.048	0.952	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.046	0.954	0.000
E21.4 Other specified disorders of parathyroid gland	0.038	0.962	0.000
S10.9 Superficial injury of neck, part unspecified	0.000	0.984	0.016
E20-E35 Disorders of other endocrine glands	0.014	0.986	0.000
G62.9 Polyneuropathy, unspecified	0.013	0.987	0.000
E22 Hyperfunction of pituitary gland	0.012	0.988	0.000
D35.1 Parathyroid gland	0.012	0.988	0.000
E22.0 Acromegaly and pituitary gigantism	0.012	0.988	0.000
E26 Hyperaldosteronism	0.011	0.989	0.000
E22.1 Hyperprolactinaemia	0.011	0.989	0.000
S10 Superficial injury of neck	0.000	0.989	0.011
E28 Ovarian dysfunction	0.010	0.990	0.000
E25 Adrenogenital disorders	0.010	0.990	0.000
E32 Diseases of thymus	0.010	0.990	0.000
E31 Polyglandular dysfunction	0.010	0.990	0.000
N32.9 Bladder disorder, unspecified	0.010	0.990	0.000
E20 Hypoparathyroidism	0.010	0.990	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.010	0.990	0.000
E30 Disorders of puberty, not elsewhere classified	0.010	0.990	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.990	0.010
E34 Other endocrine disorders	0.009	0.990	0.000
G62 Other polyneuropathies	0.009	0.991	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.009	0.991	0.000
G62.8 Other specified polyneuropathies	0.009	0.991	0.000
E29 Testicular dysfunction	0.009	0.991	0.000
E22.8 Other hyperfunction of pituitary gland	0.009	0.991	0.000
C67.3 Anterior wall of bladder	0.000	0.991	0.009
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.991	0.009
E26.9 Hyperaldosteronism, unspecified	0.009	0.991	0.000
E26.0 Primary hyperaldosteronism	0.009	0.991	0.000
G93.3 Postviral fatigue syndrome	0.000	0.991	0.009
E28.3 Primary ovarian failure	0.008	0.992	0.000
E26.8 Other hyperaldosteronism	0.008	0.992	0.000
E26.1 Secondary hyperaldosteronism	0.008	0.992	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.008	0.992	0.000
S10.1 Other and unspecified superficial injuries of throat	0.000	0.992	0.008
I08 Multiple valve diseases	0.000	0.992	0.008
E32.9 Disease of thymus, unspecified	0.008	0.992	0.000
S10.8 Superficial injury of other parts of neck	0.000	0.992	0.008
S10.7 Multiple superficial injuries of neck	0.000	0.992	0.008
S10.0 Contusion of throat	0.000	0.992	0.008
I08.0 Disorders of both mitral and aortic valves	0.000	0.992	0.008
E34.8 Other specified endocrine disorders	0.008	0.992	0.000
E31.0 Autoimmune polyglandular failure	0.008	0.992	0.000
E20.8 Other hypoparathyroidism	0.008	0.992	0.000
E28.9 Ovarian dysfunction, unspecified	0.008	0.992	0.000
E28.8 Other ovarian dysfunction	0.008	0.992	0.000
E28.1 Androgen excess	0.008	0.992	0.000
E28.0 Oestrogen excess	0.008	0.992	0.000
E25.9 Adrenogenital disorder, unspecified	0.007	0.992	0.000
E25.8 Other adrenogenital disorders	0.007	0.992	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.008	0.992	0.000
E32.8 Other diseases of thymus	0.007	0.992	0.000
E32.1 Abscess of thymus	0.007	0.992	0.000
E32.0 Persistent hyperplasia of thymus	0.007	0.992	0.000
E34.3 Short stature, not elsewhere classified	0.008	0.992	0.000
E31.9 Polyglandular dysfunction, unspecified	0.007	0.992	0.000
E31.8 Other polyglandular dysfunction	0.007	0.992	0.000
E31.1 Polyglandular hyperfunction	0.007	0.992	0.000
Y40.9 Systemic antibiotic, unspecified	0.000	0.992	0.008
E20.1 Pseudohypoparathyroidism	0.007	0.992	0.000
E20.0 Idiopathic hypoparathyroidism	0.007	0.992	0.000
E23 Hypofunction and other disorders of pituitary gland	0.007	0.992	0.000
E30.9 Disorder of puberty, unspecified	0.007	0.993	0.000
E30.8 Other disorders of puberty	0.007	0.993	0.000
E30.1 Precocious puberty	0.007	0.993	0.000
E30.0 Delayed puberty	0.007	0.993	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.007	0.993	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.007	0.993	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.007	0.993	0.000
Y40.0 Penicillins	0.000	0.993	0.007
E28.2 Polycystic ovarian syndrome	0.007	0.993	0.000
E20.9 Hypoparathyroidism, unspecified	0.007	0.993	0.000
E24 Cushing's syndrome	0.007	0.993	0.000
E34.5 Androgen resistance syndrome	0.007	0.993	0.000
E34.4 Constitutional tall stature	0.007	0.993	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.007	0.993	0.000
E34.1 Other hypersecretion of intestinal hormones	0.007	0.993	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.993	0.007
E34.0 Carcinoid syndrome	0.007	0.993	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.993	0.007
G62.2 Polyneuropathy due to other toxic agents	0.007	0.993	0.000
E29.8 Other testicular dysfunction	0.007	0.993	0.000
E29.0 Testicular hyperfunction	0.007	0.993	0.000
I08.8 Other multiple valve diseases	0.000	0.993	0.007
G62.1 Alcoholic polyneuropathy	0.007	0.993	0.000
C67.8 Overlapping lesion of bladder	0.000	0.993	0.007
E29.9 Testicular dysfunction, unspecified	0.007	0.993	0.000
S12.1 Fracture of second cervical vertebra	0.000	0.993	0.007
S12 Fracture of neck	0.000	0.993	0.007
C67 Malignant neoplasm of bladder	0.000	0.994	0.006
E29.1 Testicular hypofunction	0.006	0.994	0.000
G62.0 Drug-induced polyneuropathy	0.006	0.994	0.000
K62.3 Rectal prolapse	0.000	0.994	0.006
C67.2 Lateral wall of bladder	0.000	0.994	0.006
E23.7 Disorder of pituitary gland, unspecified	0.006	0.994	0.000
S62.60 Fracture of other finger (closed)	0.000	0.994	0.006
S10-S19 Injuries to the neck	0.000	0.994	0.006
E24.2 Drug-induced Cushing's syndrome	0.006	0.994	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.994	0.006
E23.2 Diabetes insipidus	0.006	0.994	0.000
S12.2 Fracture of other specified cervical vertebra	0.000	0.994	0.006
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.006	0.994	0.000
I08.9 Multiple valve disease, unspecified	0.000	0.994	0.006
C34.3 Lower lobe, bronchus or lung	0.000	0.994	0.006
E23.1 Drug-induced hypopituitarism	0.005	0.994	0.000
Y40 Systemic antibiotics	0.000	0.994	0.006
C67.5 Bladder neck	0.000	0.994	0.005
O46.9 Antepartum haemorrhage, unspecified	0.005	0.995	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.005	0.995	0.000
E24.3 Ectopic ACTH syndrome	0.005	0.995	0.000
E24.1 Nelson's syndrome	0.005	0.995	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.005	0.995	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.995	0.005
Z36.8 Other antenatal screening	0.000	0.995	0.005
C67.1 Dome of bladder	0.000	0.995	0.005
E24.8 Other Cushing's syndrome	0.005	0.995	0.000
S12.7 Multiple fractures of cervical spine	0.000	0.995	0.005
S12.11 Fracture of second cervical vertebra (open)	0.000	0.995	0.005
S22.30 Fracture of rib (closed)	0.000	0.995	0.005
S19 Other and unspecified injuries of neck	0.000	0.995	0.005
S12.8 Fracture of other parts of neck	0.000	0.995	0.005
C67.7 Urachus	0.000	0.995	0.005
S12.0 Fracture of first cervical vertebra	0.000	0.995	0.005
E23.6 Other disorders of pituitary gland	0.005	0.995	0.000
S17 Crushing injury of neck	0.000	0.995	0.005
S15 Injury of blood vessels at neck level	0.000	0.995	0.005
S18 Traumatic amputation at neck level	0.000	0.995	0.005
S16 Injury of muscle and tendon at neck level	0.000	0.995	0.005
S14 Injury of nerves and spinal cord at neck level	0.000	0.995	0.005
S12.9 Fracture of neck, part unspecified	0.000	0.995	0.004
E34.9 Endocrine disorder, unspecified	0.004	0.995	0.000
Y40.7 Antifungal antibiotics, systemically used	0.000	0.995	0.004
E24.0 Pituitary-dependent Cushing's disease	0.004	0.996	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.996	0.004
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.996	0.004
S12.21 Fracture of other specified cervical vertebra (open)	0.000	0.996	0.004
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.996	0.004
Y40.5 Aminoglycosides	0.000	0.996	0.004
N60.8 Other benign mammary dysplasias	0.000	0.996	0.004
Y40.2 Chloramphenicol group	0.000	0.996	0.004
S12.70 Multiple fractures of cervical spine (closed)	0.000	0.996	0.004
S19.8 Other specified injuries of neck	0.000	0.996	0.004
O14.9 Preeclampsia, unspecified	0.004	0.996	0.000
C67.4 Posterior wall of bladder	0.000	0.996	0.004
C67.0 Trigone of bladder	0.000	0.996	0.004
S22.3 Fracture of rib	0.000	0.996	0.004
S12.71 Multiple fractures of cervical spine (open)	0.000	0.996	0.004
I31 Other diseases of pericardium	0.000	0.996	0.004
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.996	0.004
I31.1 Chronic constrictive pericarditis	0.000	0.996	0.004
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.000	0.996	0.004
S19.7 Multiple injuries of neck	0.000	0.996	0.004
S12.81 Fracture of other parts of neck (open)	0.000	0.996	0.004
S12.80 Fracture of other parts of neck (closed)	0.000	0.996	0.004
Y40.6 Rifamycins	0.000	0.996	0.004
Y40.3 Macrolides	0.000	0.996	0.004
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.996	0.004
S14.3 Injury of brachial plexus	0.000	0.996	0.004
S12.01 Fracture of first cervical vertebra (open)	0.000	0.996	0.003
Y40.4 Tetracyclines	0.000	0.996	0.003
S19.9 Unspecified injury of neck	0.000	0.996	0.004
S15.9 Injury of unspecified blood vessel at neck level	0.000	0.996	0.003
S15.8 Injury of other blood vessels at neck level	0.000	0.996	0.003
S15.7 Injury of multiple blood vessels at neck level	0.000	0.996	0.003
S15.3 Injury of internal jugular vein	0.000	0.996	0.003
S15.2 Injury of external jugular vein	0.000	0.996	0.003
S15.1 Injury of vertebral artery	0.000	0.996	0.003
S15.0 Injury of carotid artery	0.000	0.996	0.003
S17.9 Crushing injury of neck, part unspecified	0.000	0.996	0.003
S17.8 Crushing injury of other parts of neck	0.000	0.996	0.003
S17.0 Crushing injury of larynx and traches	0.000	0.996	0.003
S14.6 Injury of other and unspecified nerves of neck	0.000	0.996	0.003
S14.5 Injury of cervical sympathetic nerves	0.000	0.996	0.003
S14.4 Injury of peripheral nerves of neck	0.000	0.996	0.003
S14.2 Injury of nerve root of cervical spine	0.000	0.996	0.003
S14.0 Concussion and oedema of cervical spinal cord	0.000	0.996	0.003
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.996	0.004
S12.91 Fracture of neck, part unspecified (open)	0.000	0.996	0.003
H34.8 Other retinal vascular occlusions	0.000	0.996	0.004
S12.00 Fracture of first cervical vertebra (closed)	0.000	0.996	0.003
D52.9 Folate deficiency anaemia, unspecified	0.000	0.996	0.004
H34.2 Other retinal artery occlusions	0.000	0.996	0.004
T13.0 Superficial injury of lower limb, level unspecified	0.003	0.997	0.000
N45 Orchitis and epididymitis	0.003	0.997	0.000
Y45.0 Opioids and related analgesics	0.000	0.997	0.003
Z89.4 Acquired absence of foot and ankle	0.003	0.997	0.000
R25.2 Cramp and spasm	0.000	0.997	0.003
S14.1 Other and unspecified injuries of cervical spinal cord	0.000	0.997	0.003
J84 Other interstitial pulmonary diseases	0.000	0.997	0.003
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.997	0.003
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.997	0.003
E24.9 Cushing's syndrome, unspecified	0.003	0.997	0.001
E23.0 Hypopituitarism	0.003	0.997	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.000	0.997	0.003
N17.9 Acute renal failure, unspecified	0.000	0.997	0.003
N95.2 Postmenopausal atrophic vaginitis	0.003	0.997	0.000
S22.4 Multiple fractures of ribs	0.000	0.997	0.003
S22.31 Fracture of rib (open)	0.000	0.997	0.003
S22.40 Multiple fractures of ribs (closed)	0.000	0.997	0.003
M21.3 Wrist or foot drop (acquired)	0.000	0.997	0.003
S11 Open wound of neck	0.000	0.997	0.003
I31.8 Other specified diseases of pericardium	0.000	0.997	0.003
I31.2 Haemopericardium, not elsewhere classified	0.000	0.997	0.003
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.000	0.997	0.003
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.000	0.997	0.003
S13.5 Sprain and strain of thyroid region	0.000	0.997	0.003
S13.3 Multiple dislocations of neck	0.000	0.997	0.003
S13.2 Dislocation of other and unspecified parts of neck	0.000	0.997	0.003
S13.0 Traumatic rupture of cervical intervertebral disk	0.000	0.997	0.003
S22.5 Flail chest	0.000	0.997	0.003
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.003	0.997	0.000
M21.0 Valgus deformity, not elsewhere classified	0.000	0.997	0.003
H34 Retinal vascular occlusions	0.000	0.997	0.003
S72.40 Fracture of lower end of femur (closed)	0.000	0.997	0.003
C67.6 Ureteric orifice	0.000	0.997	0.003
S13.1 Dislocation of cervical vertebra	0.000	0.997	0.003
Y45.5 4-Aminophenol derivatives	0.000	0.997	0.003
M21 Other acquired deformities of limbs	0.000	0.997	0.003
S22.50 Flail chest (closed)	0.000	0.997	0.003
S22.1 Multiple fractures of thoracic spine	0.000	0.997	0.003
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.997	0.003
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.997	0.003
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.997	0.003
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.997	0.003
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.000	0.997	0.003
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.997	0.003
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.997	0.003
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.997	0.003
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.997	0.003
Z36.2 Other antenatal screening based on amniocentesis	0.000	0.997	0.003
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.003	0.997	0.000
Y40.8 Other systemic antibiotics	0.000	0.997	0.003
L29.0 Pruritus ani	0.000	0.997	0.003
J84.8 Other specified interstitial pulmonary diseases	0.000	0.997	0.003
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.997	0.003
C22.1 Intrahepatic bile duct carcinoma	0.000	0.997	0.003
J84.0 Alveolar and parietoalveolar conditions	0.000	0.997	0.003
Y45.2 Propionic acid derivatives	0.000	0.997	0.003
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.000	0.997	0.003
H34.9 Retinal vascular occlusion, unspecified	0.000	0.997	0.003
K12.0 Recurrent oral aphthae	0.000	0.997	0.003
S22.9 Fracture of bony thorax, part unspecified	0.000	0.997	0.003
S22.8 Fracture of other parts of bony thorax	0.000	0.997	0.003
I31.0 Chronic adhesive pericarditis	0.000	0.997	0.002
I82.8 Embolism and thrombosis of other specified veins	0.000	0.997	0.003
M21.1 Varus deformity, not elsewhere classified	0.000	0.997	0.003
T13 Other injuries of lower limb, level unspecified	0.003	0.997	0.000
M21.7 Unequal limb length (acquired)	0.000	0.997	0.003
T09.0 Superficial injury of trunk, level unspecified	0.003	0.997	0.000
T14.6 Injury of tendons and muscles of unspecified body region	0.003	0.997	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.997	0.002
R25.3 Fasciculation	0.000	0.997	0.003
E27.8 Other specified disorders of adrenal gland	0.000	0.997	0.002
E27 Other disorders of adrenal gland	0.001	0.997	0.002
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.997	0.002
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.997	0.002
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.997	0.002
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.997	0.002
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.997	0.002
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.997	0.002
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.997	0.002
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.997	0.002
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.997	0.002
M21.9 Acquired deformity of limb, unspecified	0.000	0.997	0.002
S11.2 Open wound involving pharynx and cervical oesophagus	0.000	0.997	0.002
S11.1 Open wound involving thyroid gland	0.000	0.997	0.002
S11.0 Open wound involving larynx and trachea	0.000	0.997	0.002
S22.51 Flail chest (open)	0.000	0.998	0.002
G61.8 Other inflammatory polyneuropathies	0.002	0.998	0.000
G61 Inflammatory polyneuropathy	0.002	0.998	0.000
T09 Other injuries of spine and trunk, level unspecified	0.002	0.998	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.998	0.002
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.998	0.002
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.998	0.002
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.998	0.002
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
H34.0 Transient retinal artery occlusion	0.000	0.998	0.002
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.998	0.000
G64 Other disorders of peripheral nervous system	0.002	0.998	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.000	0.998	0.002
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.998	0.002
S22.2 Fracture of sternum	0.000	0.998	0.002
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.998	0.002
S11.7 Multiple open wounds of neck	0.001	0.998	0.002
T09.3 Injury of spinal cord, level unspecified	0.002	0.998	0.000
T13.2 Dislocation, strain and sprain of unspecified joint and ligament of lower limb, level unspecified	0.002	0.998	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.998	0.002
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.998	0.002
S62.6 Fracture of other finger	0.000	0.998	0.002
D35 Benign neoplasm of other and unspecified endocrine glands	0.002	0.998	0.000
T14 Injury of unspecified body region	0.002	0.998	0.000
M21.2 Flexion deformity	0.000	0.998	0.002
M21.24 Flexion deformity (Hand)	0.000	0.998	0.002
K35.1 Acute appendicitis with peritoneal abscess	0.002	0.998	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.998	0.002
G63 Polyneuropathy in diseases classified elsewhere	0.002	0.998	0.000
S73.0 Dislocation of hip	0.002	0.998	0.000
H34.1 Central retinal artery occlusion	0.000	0.998	0.002
S11.8 Open wound of other parts of neck	0.001	0.998	0.002
S13.4 Sprain and strain of cervical spine	0.000	0.998	0.002
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.998	0.002
S20.2 Contusion of thorax	0.000	0.998	0.002
S22.0 Fracture of thoracic vertebra	0.000	0.998	0.002
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.002	0.998	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.000	0.998	0.002
C64-C68 Malignant neoplasms of urinary tract	0.000	0.998	0.002
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.998	0.002
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.998	0.002
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.998	0.002
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.998	0.002
C02.9 Tongue, unspecified	0.002	0.998	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.998	0.002
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.998	0.002
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.998	0.002
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.998	0.002
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
T13.8 Other specified injuries of lower limb, level unspecified	0.002	0.998	0.000
T13.6 Traumatic amputation of lower limb, level unspecified	0.002	0.998	0.000
T13.5 Injury of unspecified muscle and tendon of lower limb, level unspecified	0.002	0.998	0.000
T13.4 Injury of unspecified blood vessel of lower limb, level unspecified	0.002	0.998	0.000
T13.3 Injury of unspecified nerve of lower limb, level unspecified	0.002	0.998	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.000	0.998	0.002
M21.78 Unequal limb length (acquired)-Other	0.000	0.998	0.002
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.000	0.998	0.002
M21.74 Unequal limb length (acquired) (Hand)	0.000	0.998	0.002
M21.72 Unequal limb length (acquired) (Upper arm)	0.000	0.998	0.002
M21.71 Unequal limb length (acquired)-Shldr region	0.000	0.998	0.002
M21.70 Unequal limb length (acquired) (Multiple sites)	0.000	0.998	0.002
Z01.8 Other specified special examinations	0.002	0.998	0.000
L05.9 Pilonidal cyst without abscess	0.000	0.998	0.002
M21.73 Unequal limb length (acquired) (Forearm)	0.000	0.998	0.002
M21.94 Acquired deformity of limb, unspecified (Hand)	0.000	0.998	0.002
I31.3 Pericardial effusion (noninflammatory)	0.000	0.998	0.002
T13.9 Unspecified injury of lower limb, level unspecified	0.002	0.998	0.000
T14.1 Open wound of unspecified body region	0.002	0.998	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.000	0.998	0.002
M21.98 Acquired deformity of limb, unspecified-Other	0.000	0.998	0.002
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.000	0.998	0.002
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.000	0.998	0.002
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.000	0.998	0.002
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.000	0.998	0.002
E27.5 Adrenomedullary hyperfunction	0.001	0.998	0.001
E27.0 Other adrenocortical overactivity	0.001	0.998	0.001
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
T09.9 Unspecified injury of trunk, level unspecified	0.002	0.998	0.000
E27.2 Addisonian crisis	0.001	0.998	0.002
C22.9 Liver, unspecified	0.000	0.998	0.002
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.998	0.002
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
S11.9 Open wound of neck, part unspecified	0.001	0.998	0.001
G61.1 Serum neuropathy	0.002	0.998	0.000
T09.8 Other specified injuries of trunk, level unspecified	0.002	0.998	0.000
T09.6 Traumatic amputation of trunk, level unspecified	0.002	0.998	0.000
T09.5 Injury of unspecified muscle and tendon of trunk	0.002	0.998	0.000
T09.4 Injury of unspecified nerve, spinal nerve root and plexus of trunk	0.002	0.998	0.000
T09.1 Open wound of trunk, level unspecified	0.002	0.998	0.000
Y45.4 Antirheumatics	0.000	0.998	0.002
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.998	0.002
M21.8 Other specified acquired deformities of limbs	0.000	0.998	0.002
G60 Hereditary and idiopathic neuropathy	0.002	0.998	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.002	0.998	0.000
E27.9 Disorder of adrenal gland, unspecified	0.001	0.998	0.001
S22.21 Fracture of sternum (open)	0.000	0.998	0.002
M21.4 Flat foot [pes planus] (acquired)	0.000	0.998	0.002
K65.9 Peritonitis, unspecified	0.002	0.998	0.000
M21.23 Flexion deformity (Forearm)	0.000	0.998	0.002
D35.9 Endocrine gland, unspecified	0.002	0.998	0.000
D35.8 Pluriglandular involvement	0.002	0.998	0.000
D35.7 Other specified endocrine glands	0.002	0.998	0.000
D35.6 Aortic body and other paraganglia	0.002	0.998	0.000
D35.5 Carotid body	0.002	0.998	0.000
D35.4 Pineal gland	0.002	0.998	0.000
D35.3 Craniopharyngeal duct	0.002	0.998	0.000
M21.6 Other acquired deformities of ankle and foot	0.000	0.998	0.002
M96.8 Other postprocedural musculoskeletal disorders	0.000	0.998	0.002
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.000	0.998	0.002
S27.1 Traumatic haemothorax	0.000	0.998	0.002
T14.2 Fracture of unspecified body region	0.002	0.998	0.000
T14.8 Other injuries of unspecified body region	0.002	0.998	0.000
T14.7 Crushing injury and traumatic amputation of unspecified body region	0.002	0.998	0.000
T14.5 Injury of blood vessel(s) of unspecified body region	0.002	0.998	0.000
T14.3 Dislocation, sprain and strain of unspecified body region	0.002	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.000	0.998	0.002
C68 Malignant neoplasm of other and unspecified urinary organs	0.000	0.998	0.002
M21.29 Flexion deformity (Site unspecified)	0.000	0.998	0.002
M21.28 Flexion deformity (Other)	0.000	0.998	0.002
M21.21 Flexion deformity (Shoulder region)	0.000	0.998	0.002
C66 Malignant neoplasm of ureter	0.000	0.998	0.002
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.000	0.998	0.002
G63.8 Polyneuropathy in other diseases classified elsewhere	0.002	0.998	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.002	0.998	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.002	0.998	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.002	0.998	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.002	0.998	0.000
G63.1 Polyneuropathy in neoplastic disease	0.002	0.998	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H33.0 Retinal detachment with retinal break	0.002	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.002	0.998	0.000
C65 Malignant neoplasm of renal pelvis	0.000	0.998	0.002
S22.01 Fracture of thoracic vertebra (open)	0.000	0.998	0.002
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
S80.9 Superficial injury of lower leg, unspecified	0.002	0.998	0.000
S27 Injury of other and unspecified intrathoracic organs	0.000	0.998	0.002
T12.X1 Fracture of lower limb, level unspecified (open)	0.002	0.998	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.002	0.998	0.000
T12 Fracture of lower limb, level unspecified	0.002	0.998	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.002	0.998	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.002	0.998	0.000
T10 Fracture of upper limb, level unspecified	0.002	0.998	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.002	0.998	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.002	0.998	0.000
M21.26 Flexion deformity (Lower leg)	0.000	0.998	0.002
S89.8 Other specified injuries of lower leg	0.002	0.998	0.000
T08 Fracture of spine, level unspecified	0.002	0.998	0.000
M21.22 Flexion deformity (Upper arm)	0.000	0.998	0.002
M21.83 Other specified acquired deformities of limbs (Forearm)	0.000	0.998	0.002
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
M21.20 Flexion deformity (Multiple sites)	0.000	0.998	0.002
O46 Antepartum haemorrhage, not elsewhere classified	0.002	0.998	0.000
T14.9 Injury, unspecified	0.002	0.998	0.000
T14.4 Injury of nerve(s) of unspecified body region	0.002	0.998	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.000	0.998	0.001
T09.2 Dislocation, strain and sprain of unspecified joint and ligament of trunk	0.002	0.998	0.000
T11 Other injuries of upper limb, level unspecified	0.002	0.998	0.000
C51.9 Vulva, unspecified	0.002	0.998	0.000
C68.9 Urinary organ, unspecified	0.000	0.998	0.002
G60.0 Hereditary motor and sensory neuropathy	0.002	0.998	0.000
S72.4 Fracture of lower end of femur	0.000	0.998	0.002
M21.25 Flexion deformity (Pelvic region and thigh)	0.000	0.998	0.002
K75.8 Other specified inflammatory liver diseases	0.000	0.998	0.002
T14.0 Superficial injury of unspecified body region	0.002	0.998	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.000	0.998	0.002
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.998	0.002
K61.3 Ischiorectal abscess	0.000	0.998	0.002
T13.1 Open wound of lower limb, level unspecified	0.001	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.998	0.001
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.998	0.001
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.998	0.001
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.998	0.001
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.998	0.001
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.998	0.001
G60.3 Idiopathic progressive neuropathy	0.001	0.998	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.001	0.998	0.000
G60.1 Refsum's disease	0.001	0.998	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.002	0.998	0.000
G61.0 Guillain-Barre syndrome	0.002	0.998	0.000
S27.2 Traumatic heamopneumothorax	0.000	0.998	0.002
S27.0 Traumatic pneumothorax	0.000	0.998	0.002
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.002	0.998	0.000
Z36 Antenatal screening	0.000	0.998	0.002
S20-S29 Injuries to the thorax	0.000	0.998	0.002
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.998	0.001
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.998	0.001
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.998	0.001
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.998	0.001
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.998	0.001
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.998	0.001
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.998	0.001
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.998	0.001
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.998	0.001
S72.41 Fracture of lower end of femur (open)	0.000	0.998	0.002
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.998	0.001
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.998	0.001
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.998	0.001
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.998	0.001
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.998	0.001
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.998	0.001
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.998	0.001
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.998	0.001
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.000	0.998	0.001
T11.1 Open wound of upper limb, level unspecified	0.002	0.998	0.000
R25 Abnormal involuntary movements	0.000	0.998	0.002
M21.27 Flexion deformity (Ankle and foot)	0.000	0.998	0.002
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.000	0.998	0.001
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.998	0.001
T14.21 Fracture of unspecified body region (open)	0.001	0.998	0.000
T14.20 Fracture of unspecified body region (closed)	0.001	0.998	0.000
C68.8 Overlapping lesion of urinary organs	0.000	0.998	0.001
C68.1 Paraurethral glands	0.000	0.998	0.001
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.000	0.998	0.002
M96.4 Postsurgical lordosis	0.000	0.998	0.002
M96.3 Postlaminectomy kyphosis	0.000	0.998	0.002
M96.2 Postradiation kyphosis	0.000	0.998	0.002
M40.29 Other and unspecified kyphosis (Site unspecified)	0.000	0.998	0.002
G63.2 Diabetic polyneuropathy	0.002	0.998	0.000
H52.0 Hypermetropia	0.002	0.998	0.000
I45.6 Preexcitation syndrome	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations