TreeWAS – Variant ID: rs6498169

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G35 Multiple sclerosis	0.000	0.780	0.220
M50.0 Cervical disk disorder with myelopathy	0.132	0.868	0.000
M50.3 Other cervical disk degeneration	0.095	0.905	0.000
M50 Cervical disk disorders	0.094	0.906	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.918	0.082
G36 Other acute disseminated demyelination	0.000	0.936	0.064
M50.9 Cervical disk disorder, unspecified	0.060	0.940	0.000
M50.8 Other cervical disk disorders	0.059	0.941	0.000
G36.0 Neuromyelitis optica [Devic]	0.000	0.949	0.051
G37 Other demyelinating diseases of central nervous system	0.000	0.953	0.047
G36.9 Acute disseminated demyelination, unspecified	0.000	0.954	0.046
G36.8 Other specified acute disseminated demyelination	0.000	0.954	0.046
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.954	0.046
M50.1 Cervical disk disorder with radiculopathy	0.043	0.957	0.000
M50.2 Other cervical disk displacement	0.042	0.958	0.000
G37.5 Concentric sclerosis [Balo]	0.000	0.966	0.034
G37.4 Subacute necrotising myelitis	0.000	0.966	0.034
G37.2 Central pontine myelinolysis	0.000	0.966	0.034
G37.1 Central demyelination of corpus callosum	0.000	0.966	0.034
G37.0 Diffuse sclerosis	0.000	0.966	0.034
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.966	0.034
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.971	0.029
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.971	0.028
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.972	0.028
F31.0 Bipolar affective disorder, current episode hypomanic	0.024	0.976	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.022	0.978	0.000
F31 Bipolar affective disorder	0.021	0.979	0.000
F31.7 Bipolar affective disorder, currently in remission	0.019	0.981	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.019	0.981	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.017	0.983	0.000
N28.8 Other specified disorders of kidney and ureter	0.016	0.984	0.000
N90.4 Leukoplakia of vulva	0.000	0.985	0.015
F31.8 Other bipolar affective disorders	0.014	0.985	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.014	0.986	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.014	0.986	0.000
M50-M54 Other dorsopathies	0.014	0.986	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.013	0.987	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.012	0.988	0.000
Z35 Supervision of high-risk pregnancy	0.012	0.988	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.000	0.988	0.012
N90 Other noninflammatory disorders of vulva and perineum	0.000	0.989	0.011
F31.9 Bipolar affective disorder, unspecified	0.011	0.989	0.000
M51 Other intervertebral disk disorders	0.011	0.989	0.000
H72 Perforation of tympanic membrane	0.000	0.990	0.010
Z35.9 Supervision of high-risk pregnancy, unspecified	0.010	0.990	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.010	0.990	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.010	0.990	0.000
S32 Fracture of lumbar spine and pelvis	0.010	0.990	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.010	0.990	0.000
N90.1 Moderate vulvar dysplasia	0.000	0.990	0.010
S32.7 Multiple fractures of lumbar spine and pelvis	0.010	0.990	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.010	0.990	0.000
S32.3 Fracture of ilium	0.010	0.990	0.000
S32.0 Fracture of lumbar vertebra	0.010	0.990	0.000
S32.30 Fracture of ilium (closed)	0.009	0.991	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.009	0.991	0.000
Z35.8 Supervision of other high-risk pregnancies	0.009	0.991	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.009	0.991	0.000
M53 Other dorsopathies, not elsewhere classified	0.009	0.991	0.000
L29.0 Pruritus ani	0.000	0.991	0.009
S32.1 Fracture of sacrum	0.009	0.991	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.009	0.991	0.000
M51.4 Schmorl's nodes	0.009	0.991	0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.000	0.991	0.009
Z35.7 Supervision of high-risk pregnancy due to social problems	0.009	0.991	0.000
Z35.6 Supervision of very young primigravida	0.009	0.991	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.009	0.991	0.000
M51.8 Other specified intervertebral disk disorders	0.008	0.991	0.000
N90.3 Dysplasia of vulva, unspecified	0.000	0.992	0.008
E05.9 Thyrotoxicosis, unspecified	0.000	0.992	0.008
N90.6 Hypertrophy of vulva	0.000	0.992	0.008
E53.8 Deficiency of other specified B group vitamins	0.000	0.992	0.008
H72.1 Attic perforation of tympanic membrane	0.000	0.992	0.008
S32.10 Fracture of sacrum (closed)	0.008	0.992	0.000
S32.2 Fracture of coccyx	0.008	0.992	0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified	0.000	0.992	0.008
M51.3 Other specified intervertebral disk degeneration	0.008	0.992	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.008	0.992	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.992	0.008
S32.4 Fracture of acetabulum	0.007	0.993	0.000
L29.9 Pruritus, unspecified	0.000	0.993	0.007
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.007	0.993	0.000
S32.5 Fracture of pubis	0.007	0.993	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.007	0.993	0.000
M53.2 Spinal instabilities	0.007	0.993	0.000
L29 Pruritus	0.000	0.993	0.007
S32.01 Fracture of lumbar vertebra (open)	0.007	0.993	0.000
S32.31 Fracture of ilium (open)	0.007	0.993	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.993	0.007
M53.8 Other specified dorsopathies	0.007	0.993	0.000
M53.1 Cervicobrachial syndrome	0.007	0.993	0.000
M53.0 Cervicocranial syndrome	0.007	0.993	0.000
H72.2 Other marginal perforations of tympanic membrane	0.000	0.993	0.007
S32.20 Fracture of coccyx (closed)	0.007	0.993	0.000
S32.11 Fracture of sacrum (open)	0.006	0.993	0.000
M53.9 Dorsopathy, unspecified	0.006	0.993	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.007	0.993	0.000
L29.8 Other pruritus	0.000	0.994	0.006
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.006	0.994	0.000
M53.82 Other specified dorsopathies (Cervical region)	0.006	0.994	0.000
N90.0 Mild vulvar dysplasia	0.000	0.994	0.006
S32.21 Fracture of coccyx (open)	0.006	0.994	0.000
R40.2 Coma, unspecified	0.006	0.994	0.000
M51.9 Intervertebral disk disorder, unspecified	0.006	0.994	0.000
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.006	0.994	0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.006	0.994	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.994	0.006
I74.5 Embolism and thrombosis of iliac artery	0.006	0.994	0.000
M53.22 Spinal instabilities (Cervical region)	0.005	0.994	0.000
S32.41 Fracture of acetabulum (open)	0.005	0.994	0.000
M53.26 Spinal instabilities (Lumbar region)	0.005	0.994	0.000
S32.40 Fracture of acetabulum (closed)	0.006	0.994	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.005	0.994	0.000
S32.51 Fracture of pubis (open)	0.005	0.994	0.000
N90.7 Vulvar cyst	0.000	0.995	0.005
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.005	0.995	0.000
L29.1 Pruritus scroti	0.000	0.995	0.005
M53.29 Spinal instabilities (Site unspecified)	0.005	0.995	0.000
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)	0.005	0.995	0.000
M53.25 Spinal instabilities (Thoracolumbar region)	0.005	0.995	0.000
M53.24 Spinal instabilities (Thoracic region)	0.005	0.995	0.000
M53.23 Spinal instabilities (Cervicothoracic region)	0.005	0.995	0.000
M53.21 Spinal instabilities (Occipito-atlanto-axial region)	0.005	0.995	0.000
M53.20 Spinal instabilities (Multiple sites in spine)	0.005	0.995	0.000
M53.89 Other specified dorsopathies (Site unspecified)	0.005	0.995	0.000
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)	0.005	0.995	0.000
M53.87 Other specified dorsopathies (Lumbosacral region)	0.005	0.995	0.000
M53.85 Other specified dorsopathies (Thoracolumbar region)	0.005	0.995	0.000
M53.84 Other specified dorsopathies (Thoracic region)	0.005	0.995	0.000
M53.83 Other specified dorsopathies (Cervicothoracic region)	0.005	0.995	0.000
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)	0.005	0.995	0.000
M53.80 Other specified dorsopathies (Multiple sites in spine)	0.005	0.995	0.000
S32.50 Fracture of pubis (closed)	0.005	0.995	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.005	0.995	0.000
E53 Deficiency of other B group vitamins	0.000	0.995	0.005
M53.27 Spinal instabilities (Lumbosacral region)	0.005	0.995	0.000
M53.09 Cervicocranial syndrome-Site unspe	0.005	0.995	0.000
M53.08 Cervicocranial syndrome-Sacral/sacrococ	0.005	0.995	0.000
M53.07 Cervicocranial syndrome-Lumbosacral	0.005	0.995	0.000
M53.06 Cervicocranial syndrome-Lumbar	0.005	0.995	0.000
M53.05 Cervicocranial syndrome-Thoracolumbar	0.005	0.995	0.000
M53.04 Cervicocranial syndrome-Thoracic	0.005	0.995	0.000
M53.03 Cervicocranial syndrome (Cervicothoracic region)	0.005	0.995	0.000
M53.02 Cervicocranial syndrome (Cervical region)	0.005	0.995	0.000
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)	0.005	0.995	0.000
M53.00 Cervicocranial syndrome (Multiple sites in spine)	0.005	0.995	0.000
M53.19 Cervicobrachial syndrome-Site unspe	0.005	0.995	0.000
M53.18 Cervicobrachial syndrome-Sacral/sacrococ	0.005	0.995	0.000
M53.17 Cervicobrachial syndrome-Lumbosacral	0.005	0.995	0.000
M53.16 Cervicobrachial syndrome-Lumbar	0.005	0.995	0.000
M53.15 Cervicobrachial syndrome-Thoracolumbar	0.005	0.995	0.000
M53.14 Cervicobrachial syndrome-Thoracic	0.005	0.995	0.000
M53.13 Cervicobrachial syndrome (Cervicothoracic region)	0.005	0.995	0.000
M53.12 Cervicobrachial syndrome (Cervical region)	0.005	0.995	0.000
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)	0.005	0.995	0.000
M53.10 Cervicobrachial syndrome (Multiple sites in spine)	0.005	0.995	0.000
L29.3 Anogenital pruritus, unspecified	0.000	0.995	0.005
S00.2 Other superficial injuries of eyelid and periocular area	0.000	0.995	0.005
M53.96 Dorsopathy, unspecified (Lumbar region)	0.005	0.995	0.000
I74 Arterial embolism and thrombosis	0.005	0.995	0.000
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.005	0.995	0.000
M53.97 Dorsopathy, unspecified (Lumbosacral region)	0.005	0.995	0.000
M53.95 Dorsopathy, unspecified (Thoracolumbar region)	0.005	0.995	0.000
M53.94 Dorsopathy, unspecified (Thoracic region)	0.005	0.995	0.000
M53.93 Dorsopathy, unspecified (Cervicothoracic region)	0.005	0.995	0.000
M53.92 Dorsopathy, unspecified (Cervical region)	0.005	0.995	0.000
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)	0.005	0.995	0.000
M53.90 Dorsopathy, unspecified (Multiple sites in spine)	0.005	0.995	0.000
E53.9 Vitamin B deficiency, unspecified	0.000	0.995	0.005
L03.0 Cellulitis of finger and toe	0.000	0.995	0.005
K74.3 Primary biliary cirrhosis	0.000	0.995	0.005
M53.99 Dorsopathy, unspecified (Site unspecified)	0.004	0.995	0.000
Z35.5 Supervision of elderly primigravida	0.005	0.995	0.000
M53.86 Other specified dorsopathies (Lumbar region)	0.004	0.996	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.004	0.996	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.004	0.996	0.000
L29.2 Pruritus vulvae	0.000	0.996	0.004
I35.2 Aortic (valve) stenosis with insufficiency	0.004	0.996	0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.004	0.996	0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.004	0.996	0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.004	0.996	0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.004	0.996	0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.004	0.996	0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.004	0.996	0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.004	0.996	0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.004	0.996	0.000
E53.1 Pyridoxine deficiency	0.000	0.996	0.004
E53.0 Riboflavin deficiency	0.000	0.996	0.004
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.004	0.996	0.000
N90.5 Atrophy of vulva	0.000	0.996	0.004
I74.8 Embolism and thrombosis of other arteries	0.004	0.996	0.000
H52.0 Hypermetropia	0.000	0.996	0.004
S02.80 Fractures of other skull and facial bones (closed)	0.004	0.996	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.004	0.996	0.000
K29.5 Chronic gastritis, unspecified	0.000	0.996	0.004
O00.1 Tubal pregnancy	0.000	0.997	0.003
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.003	0.997	0.000
Q39.4 Oesophageal web	0.000	0.997	0.003
K91.3 Postoperative intestinal obstruction	0.003	0.997	0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.003	0.997	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.997	0.003
N42 Other disorders of prostate	0.003	0.997	0.000
F60.9 Personality disorder, unspecified	0.003	0.997	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.003	0.997	0.000
N42.9 Disorder of prostate, unspecified	0.003	0.997	0.000
D43.2 Brain, unspecified	0.000	0.997	0.003
N42.1 Congestion and haemorrhage of prostate	0.003	0.997	0.000
N42.8 Other specified disorders of prostate	0.003	0.997	0.000
K74.5 Biliary cirrhosis, unspecified	0.000	0.997	0.003
N42.2 Atrophy of prostate	0.003	0.997	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
M48.09 Spinal stenosis (Site unspecified)	0.003	0.997	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.997	0.003
F60.3 Emotionally unstable personality disorder	0.003	0.997	0.000
N89.5 Stricture and atresia of vagina	0.000	0.997	0.003
Z12.5 Special screening examination for neoplasm of prostate	0.003	0.997	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.003	0.997	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.003	0.997	0.000
F60 Specific personality disorders	0.003	0.997	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.997	0.003
K74.6 Other and unspecified cirrhosis of liver	0.000	0.997	0.003
N42.0 Calculus of prostate	0.003	0.997	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.002	0.997	0.000
N42.3 Dysplasia of prostate	0.003	0.997	0.000
D13.1 Stomach	0.000	0.997	0.003
A49.1 Streptococcal infection, unspecified	0.000	0.997	0.003
F60.6 Anxious [avoidant] personality disorder	0.003	0.997	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.003	0.997	0.000
Z50.0 Cardiac rehabilitation	0.003	0.997	0.000
K05.3 Chronic periodontitis	0.000	0.997	0.003
K74.4 Secondary biliary cirrhosis	0.000	0.997	0.002
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.997	0.002
K74.0 Hepatic fibrosis	0.000	0.997	0.003
A49.0 Staphylococcal infection, unspecified	0.000	0.997	0.002
K74.1 Hepatic sclerosis	0.000	0.997	0.002
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.998	0.002
F60.0 Paranoid personality disorder	0.002	0.998	0.000
F60.5 Anankastic personality disorder	0.002	0.998	0.000
S29.9 Unspecified injury of thorax	0.000	0.998	0.002
M13.00 Polyarthritis, unspecified (Multiple sites)	0.000	0.998	0.002
C83.0 Small cell (diffuse)	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
F30-F39 Mood [affective] disorders	0.002	0.998	0.000
F60.4 Histrionic personality disorder	0.002	0.998	0.000
F60.1 Schizoid personality disorder	0.002	0.998	0.000
Q39 Congenital malformations of oesophagus	0.000	0.998	0.002
F60.8 Other specific personality disorders	0.002	0.998	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.002	0.998	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.998	0.002
A16.2 Tuberculosis of lung, without mention of bacteriological or histological confirmation	0.000	0.998	0.002
R52.1 Chronic intractable pain	0.000	0.998	0.002
S31.4 Open wound of vagina and vulva	0.002	0.998	0.000
F60.7 Dependent personality disorder	0.002	0.998	0.000
H69.9 Eustachian tube disorder, unspecified	0.002	0.998	0.000
Z50.1 Other physical therapy	0.000	0.998	0.002
F60.2 Dissocial personality disorder	0.002	0.998	0.000
K38.8 Other specified diseases of appendix	0.000	0.998	0.002
F39 Unspecified mood [affective] disorder	0.002	0.998	0.000
N89.6 Tight hymenal ring	0.000	0.998	0.002
N89 Other noninflammatory disorders of vagina	0.000	0.998	0.002
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.000	0.998	0.002
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.000	0.998	0.002
Z29.1 Prophylactic immunotherapy	0.000	0.998	0.002
S31 Open wound of abdomen, lower back and pelvis	0.002	0.998	0.000
K01.1 Impacted teeth	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.002
E05.5 Thyroid crisis or storm	0.000	0.998	0.002
E05.4 Thyrotoxicosis factitia	0.000	0.998	0.002
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.998	0.002
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.998	0.002
M00.9 Pyogenic arthritis, unspecified	0.000	0.998	0.002
N89.0 Mild vaginal dysplasia	0.000	0.998	0.002
F38 Other mood [affective] disorders	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.000	0.998	0.002
C43.3 Malignant melanoma of other and unspecified parts of face	0.002	0.998	0.000
E05.8 Other thyrotoxicosis	0.000	0.998	0.002
F38.0 Other single mood [affective] disorders	0.002	0.998	0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.000	0.998	0.002
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
G54.9 Nerve root and plexus disorder, unspecified	0.002	0.998	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.000	0.998	0.002
Q39.6 Diverticulum of oesophagus	0.000	0.998	0.002
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
J92.0 Pleural plaque with presence of asbestos	0.000	0.998	0.002
N89.9 Noninflammatory disorder of vagina, unspecified	0.000	0.998	0.002
Q39.8 Other congenital malformations of oesophagus	0.000	0.998	0.002
Q39.5 Congenital dilatation of oesophagus	0.000	0.998	0.002
Q39.3 Congenital stenosis and stricture of oesophagus	0.000	0.998	0.002
Q39.2 Congenital tracheooesophageal fistula without atresia	0.000	0.998	0.002
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.000	0.998	0.002
Q39.0 Atresia of oesophagus without fistula	0.000	0.998	0.002
S31.1 Open wound of abdominal wall	0.002	0.998	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.998	0.002
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.998	0.002
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.002
F20.5 Residual schizophrenia	0.002	0.998	0.000
Z57.3 Occupational exposure to other air contaminants	0.000	0.998	0.002
F20 Schizophrenia	0.002	0.998	0.000
F29 Unspecified nonorganic psychosis	0.002	0.998	0.000
N26 Unspecified contracted kidney	0.000	0.998	0.002
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.002	0.998	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.002	0.998	0.000
J30.4 Allergic rhinitis, unspecified	0.000	0.998	0.002
L73.2 Hidradenitis suppurativa	0.000	0.998	0.002
S31.8 Open wound of other and unspecified parts of abdomen	0.002	0.998	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
E06.3 Autoimmune thyroiditis	0.000	0.998	0.002
N89.4 Leukoplakia of vagina	0.000	0.998	0.002
N89.1 Moderate vaginal dysplasia	0.000	0.998	0.002
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.998	0.002
N89.3 Dysplasia of vagina, unspecified	0.000	0.998	0.002
S68.0 Traumatic amputation of thumb (complete)(partial)	0.002	0.998	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.002	0.998	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.002	0.998	0.000
F20.9 Schizophrenia, unspecified	0.002	0.998	0.000
N89.7 Haematocolpos	0.000	0.998	0.002
N89.2 Severe vaginal dysplasia, not elsewhere classified	0.000	0.998	0.002
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.998	0.002
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.998	0.002
S31.5 Open wound of other and unspecified external genital organs	0.002	0.998	0.000
A49 Bacterial infection of unspecified site	0.000	0.998	0.002
N28 Other disorders of kidney and ureter, not elsewhere classified	0.002	0.998	0.000
M00.98 Pyogenic arthritis, unspecified (Other)	0.000	0.998	0.002
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.000	0.998	0.002
T18.1 Foreign body in oesophagus	0.000	0.998	0.002
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M00.94 Pyogenic arthritis, unspecified (Hand)	0.000	0.998	0.002
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.002	0.998	0.000
D13.0 Oesophagus	0.000	0.998	0.002
F20.8 Other schizophrenia	0.002	0.998	0.000
F38.1 Other recurrent mood [affective] disorders	0.002	0.998	0.000
Q21.1 Atrial septal defect	0.000	0.998	0.002
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.002	0.998	0.000
S31.2 Open wound of penis	0.002	0.998	0.000
H47.2 Optic atrophy	0.002	0.998	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.000	0.998	0.002
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.002	0.998	0.000
J30.1 Allergic rhinitis due to pollen	0.000	0.998	0.002
S31.3 Open wound of scrotum and testes	0.002	0.998	0.000
F34 Persistent mood [affective] disorders	0.002	0.998	0.000
F20.2 Catatonic schizophrenia	0.002	0.998	0.000
F23 Acute and transient psychotic disorders	0.002	0.998	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.002	0.998	0.000
D13.4 Liver	0.000	0.998	0.002
S31.0 Open wound of lower back and pelvis	0.002	0.998	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.002	0.998	0.000
C83.3 Large cell (diffuse)	0.002	0.998	0.000
C83.1 Small cleaved cell (diffuse)	0.002	0.998	0.000
D13.6 Pancreas	0.000	0.998	0.002
H43.1 Vitreous haemorrhage	0.000	0.998	0.002
N28.0 Ischaemia and infarction of kidney	0.002	0.998	0.000
F20.6 Simple schizophrenia	0.001	0.998	0.000
F20.4 Postschizophrenic depression	0.001	0.998	0.000
F20.3 Undifferentiated schizophrenia	0.001	0.998	0.000
F20.1 Hebephrenic schizophrenia	0.001	0.998	0.000
S02.8 Fractures of other skull and facial bones	0.002	0.998	0.000
S50.0 Contusion of elbow	0.000	0.998	0.002
M13.06 Polyarthritis, unspecified (Lower leg)	0.000	0.998	0.002
F25.1 Schizoaffective disorder, depressive type	0.002	0.998	0.000
M13.0 Polyarthritis, unspecified	0.000	0.998	0.002
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.001	0.998	0.000
F38.8 Other specified mood [affective] disorders	0.001	0.998	0.000
N94.3 Premenstrual tension syndrome	0.000	0.998	0.002
J30.0 Vasomotor rhinitis	0.000	0.998	0.002
S35.2 Injury of coeliac or mesenteric artery	0.001	0.998	0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.000	0.998	0.002
F25 Schizoaffective disorders	0.002	0.998	0.000
F21 Schizotypal disorder	0.001	0.998	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.001	0.998	0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.000	0.998	0.001
A49.2 Haemophilus influenzae infection, unspecified	0.000	0.998	0.001
M51.2 Other specified intervertebral disk displacement	0.002	0.998	0.000
S36 Injury of intra-abdominal organs	0.001	0.998	0.000
A49.3 Mycoplasma infection, unspecified	0.000	0.998	0.001
Q18.1 Preauricular sinus and cyst	0.001	0.998	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.002	0.998	0.000
R40 Somnolence, stupor and coma	0.002	0.998	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.001	0.998	0.000
D13.9 Ill-defined sites within the digestive system	0.000	0.998	0.001
F25.0 Schizoaffective disorder, manic type	0.001	0.998	0.000
Q51.2 Other doubling of uterus	0.001	0.998	0.000
S36.0 Injury of spleen	0.001	0.998	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.001	0.998	0.000
F34.8 Other persistent mood [affective] disorders	0.001	0.998	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.001	0.998	0.000
Q21 Congenital malformations of cardiac septa	0.000	0.998	0.001
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.001
M13.09 Polyarthritis, unspecified (Site unspecified)	0.000	0.998	0.001
M13.04 Polyarthritis, unspecified (Hand)	0.000	0.998	0.001
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation	0.000	0.998	0.001
F23.8 Other acute and transient psychotic disorders	0.001	0.998	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.001	0.998	0.000
H33.3 Retinal breaks without detachment	0.000	0.998	0.001
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.000	0.998	0.001
F28 Other nonorganic psychotic disorders	0.001	0.998	0.000
F24 Induced delusional disorder	0.001	0.998	0.000
S37 Injury of urinary and pelvic organs	0.001	0.998	0.000
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.001	0.999	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.001	0.999	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.001	0.999	0.000
S35.5 Injury of iliac blood vessels	0.001	0.999	0.000
S35.4 Injury of renal blood vessels	0.001	0.999	0.000
S35.3 Injury of portal or splenic vein	0.001	0.999	0.000
S35.1 Injury of inferior vena cava	0.001	0.999	0.000
S35.0 Injury of abdominal aorta	0.001	0.999	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.000	0.999	0.001
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.001	0.999	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.999	0.001
D13.3 Other and unspecified parts of small intestine	0.000	0.999	0.001
I80.8 Phlebitis and thrombophlebitis of other sites	0.001	0.999	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.000	0.999	0.001
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.001	0.999	0.000
S02.81 Fractures of other skull and facial bones (open)	0.001	0.999	0.000
S52.20 Fracture of shaft of ulna (closed)	0.000	0.999	0.001
F25.2 Schizoaffective disorder, mixed type	0.001	0.999	0.000
F34.0 Cyclothymia	0.001	0.999	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.001	0.999	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.999	0.001
Z80.8 Family history of malignant neoplasm of other organs or systems	0.001	0.999	0.000
M13.08 Polyarthritis, unspecified (Other)	0.000	0.999	0.001
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.000	0.999	0.001
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M13.03 Polyarthritis, unspecified (Forearm)	0.000	0.999	0.001
M13.02 Polyarthritis, unspecified (Upper arm)	0.000	0.999	0.001
M13.01 Polyarthritis, unspecified (Shoulder region)	0.000	0.999	0.001
C67.5 Bladder neck	0.000	0.999	0.001
D13.7 Endocrine pancreas	0.000	0.999	0.001
K86.8 Other specified diseases of pancreas	0.000	0.999	0.001
Q07.0 Arnold-Chiari syndrome	0.000	0.999	0.001
S36.4 Injury of small intestine	0.001	0.999	0.000
E06 Thyroiditis	0.000	0.999	0.001
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.001	0.999	0.000
A16.8 Other respiratory tuberculosis, without mention of bacteriological or histological confirmation	0.000	0.999	0.001
A16.7 Primary respiratory tuberculosis without mention of bacteriological or histological confirmation	0.000	0.999	0.001
A16.5 Tuberculous pleurisy, without mention of bacteriological or histological confirmation	0.000	0.999	0.001
A16.4 Tuberculosis of larynx, trachea and bronchus, without mention of bacteriological or histological confirmation	0.000	0.999	0.001
A16.3 Tuberculosis of intrathoracic lymph nodes, without mention of bacteriological or histological confirmation	0.000	0.999	0.001
A16.1 Tuberculosis of lung, bacteriological and histological examination not done	0.000	0.999	0.001
A16.0 Tuberculosis of lung, bacteriologically and histologically negative	0.000	0.999	0.001
C83.2 Mixed small and large cell (diffuse)	0.001	0.999	0.000
F25.8 Other schizoaffective disorders	0.001	0.999	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.001	0.999	0.000
S36.5 Injury of colon	0.001	0.999	0.000
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.001	0.999	0.000
S38.2 Traumatic amputation of external genital organs	0.001	0.999	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.001	0.999	0.000
S38.0 Crushing injury of external genital organs	0.001	0.999	0.000
Z93.1 Gastrostomy status	0.001	0.999	0.000
U88 Agent resistant to multiple antibiotics	0.000	0.999	0.001
S36.41 Injury of small intestine (with open wound into cavity)	0.001	0.999	0.000
D13.5 Extrahepatic bile ducts	0.000	0.999	0.001
E07.9 Disorder of thyroid, unspecified	0.000	0.999	0.001
F23.3 Other acute predominantly delusional psychotic disorders	0.001	0.999	0.000
J39.2 Other diseases of pharynx	0.000	0.999	0.001
S36.9 Injury of unspecified intra-abdominal organ	0.001	0.999	0.000
S36.7 Injury of multiple intra-abdominal organs	0.001	0.999	0.000
S36.6 Injury of rectum	0.001	0.999	0.000
S36.3 Injury of stomach	0.001	0.999	0.000
S36.2 Injury of pancreas	0.001	0.999	0.000
C83.6 Undifferentiated (diffuse)	0.001	0.999	0.000
C83.5 Lymphoblastic (diffuse)	0.001	0.999	0.000
C83.4 Immunoblastic (diffuse)	0.001	0.999	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.999	0.001
F20.0 Paranoid schizophrenia	0.001	0.999	0.000
G54.8 Other nerve root and plexus disorders	0.001	0.999	0.000
Q51.3 Bicornate uterus	0.001	0.999	0.000
R40.1 Stupor	0.001	0.999	0.000
S36.01 Injury of spleen (with open wound into cavity)	0.001	0.999	0.000
C67.1 Dome of bladder	0.000	0.999	0.001
C83.7 Burkitt's tumour	0.001	0.999	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.999	0.001
S37.0 Injury of kidney	0.001	0.999	0.000
F30 Manic episode	0.001	0.999	0.000
C43.9 Malignant melanoma of skin, unspecified	0.001	0.999	0.000
E06.5 Other chronic thyroiditis	0.000	0.999	0.001
Q21.4 Aortopulmonary septal defect	0.000	0.999	0.001
Q21.2 Atrioventricular septal defect	0.000	0.999	0.001
S37.9 Injury of unspecified pelvic organ	0.001	0.999	0.000
S37.8 Injury of other pelvic organs	0.001	0.999	0.000
S37.7 Injury of multiple pelvic organs	0.001	0.999	0.000
S37.6 Injury of uterus	0.001	0.999	0.000
S37.5 Injury of Fallopian tube	0.001	0.999	0.000
S37.4 Injury of ovary	0.001	0.999	0.000
S37.1 Injury of ureter	0.001	0.999	0.000
J30 Vasomotor and allergic rhinitis	0.000	0.999	0.001
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.999	0.001
F34.1 Dysthymia	0.001	0.999	0.000
N87.1 Moderate cervical dysplasia	0.000	0.999	0.001
Q21.9 Congenital malformation of cardiac septum, unspecified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations