TreeWAS – Variant ID: rs6509942

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T39.1 4-Aminophenol derivatives	0.442	0.558	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.437	0.563	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.421	0.579	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.352	0.648	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.352	0.648	0.000
T39.0 Salicylates	0.345	0.654	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.345	0.655	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.326	0.674	0.000
T39.4 Antirheumatics, not elsewhere classified	0.314	0.686	0.000
T39.2 Pyrazolone derivatives	0.314	0.686	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.298	0.702	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.297	0.703	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.294	0.706	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.285	0.715	0.000
T36 Poisoning by systemic antibiotics	0.264	0.735	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.262	0.738	0.000
T40.2 Other opioids	0.260	0.740	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.259	0.740	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.257	0.743	0.000
T43.2 Other and unspecified antidepressants	0.256	0.744	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.254	0.745	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.253	0.747	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.252	0.748	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.249	0.751	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.244	0.756	0.000
T43.9 Psychotropic drug, unspecified	0.241	0.759	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.235	0.765	0.000
T43.6 Psychostimulants with abuse potential	0.234	0.766	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.234	0.766	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.231	0.769	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.228	0.772	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.220	0.780	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.219	0.781	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.219	0.781	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.217	0.783	0.000
T38.0 Glucocorticoids and synthetic analogues	0.217	0.783	0.000
T38.5 Other oestrogens and progestogens	0.216	0.784	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.216	0.784	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.214	0.786	0.000
T46.7 Peripheral vasodilators	0.214	0.786	0.000
T38.1 Thyroid hormones and substitutes	0.213	0.787	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.213	0.787	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.213	0.787	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.212	0.788	0.000
T38.9 Other and unspecified hormone antagonists	0.211	0.789	0.000
T38.7 Androgens and anabolic congeners	0.211	0.789	0.000
T38.4 Oral contraceptives	0.211	0.789	0.000
T38.2 Antithyroid drugs	0.211	0.789	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.211	0.789	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.209	0.791	0.000
T40.5 Cocaine	0.207	0.793	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.206	0.794	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.205	0.795	0.000
T40.8 Lysergide [LSD]	0.205	0.795	0.000
T40.7 Cannabis (derivatives)	0.205	0.795	0.000
T40.0 Opium	0.205	0.795	0.000
T40.1 Heroin	0.204	0.796	0.000
T40.3 Methadone	0.202	0.797	0.000
T46.1 Calcium-channel blockers	0.201	0.799	0.000
C34.9 Bronchus or lung, unspecified	0.000	0.799	0.201
T36.3 Macrolides	0.197	0.802	0.000
T36.4 Tetracyclines	0.197	0.803	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.196	0.804	0.000
T36.8 Other systemic antibiotics	0.195	0.805	0.000
T48.5 Anti-common-cold drugs	0.195	0.805	0.000
T40.6 Other and unspecified narcotics	0.192	0.807	0.000
T36.0 Penicillins	0.192	0.808	0.000
T47.0 Histamine H(2)-receptor antagonists	0.191	0.809	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.190	0.809	0.000
T47.4 Other laxatives	0.190	0.810	0.000
T36.9 Systemic antibiotic, unspecified	0.190	0.810	0.000
T36.7 Antifungal antibiotics, systemically used	0.190	0.810	0.000
T36.6 Rifamycins	0.190	0.810	0.000
T36.5 Aminoglycosides	0.190	0.810	0.000
T36.2 Chloramphenicol group	0.190	0.810	0.000
T41.2 Other and unspecified general anaesthetics	0.189	0.811	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.188	0.812	0.000
T48.4 Expectorants	0.188	0.812	0.000
T48.3 Antitussives	0.188	0.812	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.188	0.812	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.188	0.812	0.000
T48.0 Oxytocic drugs	0.188	0.812	0.000
T41.5 Therapeutic gases	0.184	0.815	0.000
T41.4 Anaesthetic, unspecified	0.184	0.815	0.000
T41.3 Local anaesthetics	0.184	0.815	0.000
T41.1 Intravenous anaesthetics	0.184	0.815	0.000
T41.0 Inhaled anaesthetics	0.184	0.815	0.000
T47.2 Stimulant laxatives	0.183	0.817	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.183	0.817	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.183	0.817	0.000
T47.7 Emetics	0.183	0.817	0.000
T47.5 Digestants	0.183	0.817	0.000
T47.3 Saline and osmotic laxatives	0.183	0.817	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.181	0.818	0.000
T49.9 Topical agent, unspecified	0.181	0.819	0.000
T49.8 Other topical agents	0.181	0.819	0.000
T49.7 Dental drugs, topically applied	0.181	0.819	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.181	0.819	0.000
T49.5 Ophthalmological drugs and preparations	0.181	0.819	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.181	0.819	0.000
T49.3 Emollients, demulcents and protectants	0.181	0.819	0.000
T49.2 Local astringents and local detergents	0.181	0.819	0.000
T49.1 Antipruritics	0.181	0.819	0.000
T47.6 Antidiarrhoeal drugs	0.181	0.819	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.179	0.821	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.179	0.821	0.000
T37.5 Antiviral drugs	0.179	0.821	0.000
T37.4 Anthelminthics	0.179	0.821	0.000
T37.3 Other antiprotozoal drugs	0.179	0.821	0.000
T37.1 Antimycobacterial drugs	0.179	0.821	0.000
T37.0 Sulphonamides	0.179	0.821	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.178	0.822	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.177	0.823	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.177	0.823	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.168	0.831	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.165	0.834	0.000
T45.8 Other primarily systemic and haematological agents	0.165	0.834	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.165	0.834	0.000
T45.6 Fibrinolysis-affecting drugs	0.165	0.834	0.000
T45.3 Enzymes, not elsewhere classified	0.165	0.834	0.000
C34 Malignant neoplasm of bronchus and lung	0.000	0.835	0.165
T45.5 Anticoagulants	0.163	0.836	0.000
T45.4 Iron and its compounds	0.163	0.837	0.000
T50.4 Drugs affecting uric acid metabolism	0.160	0.840	0.000
T40.4 Other synthetic narcotics	0.157	0.842	0.000
T42.1 Iminostilbenes	0.155	0.845	0.000
T50.1 Loop [high-ceiling] diuretics	0.154	0.846	0.000
T45.2 Vitamins, not elsewhere classified	0.153	0.846	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.846	0.154
T50.7 Analeptics and opioid receptor antagonists	0.150	0.850	0.000
T50.5 Appetite depressants	0.150	0.850	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.150	0.850	0.000
T50.0 Mineralocorticoids and their antagonists	0.150	0.850	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.149	0.851	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.147	0.852	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.147	0.852	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.147	0.852	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.147	0.852	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.147	0.852	0.000
T44.0 Anticholinesterase agents	0.147	0.852	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.148	0.852	0.000
T45.0 Antiallergic and antiemetic drugs	0.147	0.853	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.147	0.853	0.000
T42.3 Barbiturates	0.146	0.854	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.144	0.856	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.142	0.858	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.142	0.858	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.141	0.859	0.000
T42.2 Succinimides and oxazolidinediones	0.141	0.859	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.140	0.860	0.000
T42.0 Hydantoin derivatives	0.133	0.866	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.131	0.869	0.000
T50.8 Diagnostic agents	0.128	0.871	0.000
C34.3 Lower lobe, bronchus or lung	0.000	0.878	0.122
C34.2 Middle lobe, bronchus or lung	0.000	0.881	0.119
C34.8 Overlapping lesion of bronchus and lung	0.000	0.885	0.115
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.114	0.886	0.000
C34.0 Main bronchus	0.000	0.891	0.109
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.107	0.893	0.000
T42.4 Benzodiazepines	0.090	0.910	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.913	0.087
C32 Malignant neoplasm of larynx	0.000	0.929	0.071
C33 Malignant neoplasm of trachea	0.000	0.931	0.069
C37 Malignant neoplasm of thymus	0.000	0.937	0.063
C32.1 Supraglottis	0.000	0.937	0.063
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.937	0.062
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.939	0.061
C31 Malignant neoplasm of accessory sinuses	0.000	0.940	0.060
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.942	0.058
C32.2 Subglottis	0.000	0.946	0.053
C32.9 Larynx, unspecified	0.000	0.948	0.052
C32.8 Overlapping lesion of larynx	0.000	0.949	0.051
H91.9 Hearing loss, unspecified	0.050	0.950	0.000
C32.3 Laryngeal cartilage	0.000	0.951	0.049
C39.9 Ill-defined sites within the respiratory system	0.000	0.955	0.045
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.000	0.955	0.045
C39.0 Upper respiratory tract, part unspecified	0.000	0.955	0.045
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.000	0.956	0.044
C38.2 Posterior mediastinum	0.000	0.956	0.044
C38.1 Anterior mediastinum	0.000	0.956	0.044
C38.0 Heart	0.000	0.956	0.044
C38.3 Mediastinum, part unspecified	0.000	0.956	0.043
C31.9 Accessory sinus, unspecified	0.000	0.957	0.043
C31.8 Overlapping lesion of accessory sinuses	0.000	0.957	0.043
C31.3 Sphenoidal sinus	0.000	0.957	0.043
C31.2 Frontal sinus	0.000	0.957	0.043
C31.1 Ethmoidal sinus	0.000	0.957	0.043
C38.4 Pleura	0.000	0.957	0.043
C30.1 Middle ear	0.000	0.958	0.042
C31.0 Maxillary sinus	0.000	0.959	0.041
C32.0 Glottis	0.000	0.960	0.040
C30.0 Nasal cavity	0.000	0.962	0.037
H91 Other hearing loss	0.033	0.967	0.000
H65.3 Chronic mucoid otitis media	0.028	0.972	0.000
H65 Nonsuppurative otitis media	0.027	0.973	0.000
H91.0 Ototoxic hearing loss	0.025	0.975	0.000
H91.1 Presbycusis	0.024	0.976	0.000
H91.2 Sudden idiopathic hearing loss	0.024	0.976	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.023	0.977	0.000
H91.3 Deaf mutism, not elsewhere classified	0.023	0.977	0.000
H90-H95 Other disorders of ear	0.023	0.977	0.000
H65.2 Chronic serous otitis media	0.023	0.977	0.000
H91.8 Other specified hearing loss	0.023	0.977	0.000
H65-H75 Diseases of middle ear and mastoid	0.022	0.977	0.000
Chapter VIII Diseases of the ear and mastoid process	0.021	0.979	0.000
H72 Perforation of tympanic membrane	0.021	0.979	0.000
H65.1 Other acute nonsuppurative otitis media	0.020	0.980	0.000
H65.0 Acute serous otitis media	0.019	0.981	0.000
H80-H83 Diseases of inner ear	0.019	0.981	0.000
H65.4 Other chronic nonsuppurative otitis media	0.019	0.981	0.000
H72.0 Central perforation of tympanic membrane	0.019	0.981	0.000
H81 Disorders of vestibular function	0.018	0.982	0.000
H72.8 Other perforations of tympanic membrane	0.018	0.982	0.000
H93 Other disorders of ear, not elsewhere classified	0.017	0.982	0.000
H81.0 Meniere's disease	0.017	0.983	0.000
H70 Mastoiditis and related conditions	0.017	0.983	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.017	0.983	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.016	0.983	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.016	0.984	0.000
H67 Otitis media in diseases classified elsewhere	0.016	0.984	0.000
H68 Eustachian salpingitis and obstruction	0.016	0.984	0.000
H93.1 Tinnitus	0.016	0.984	0.000
H81.1 Benign paroxysmal vertigo	0.016	0.984	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.016	0.984	0.000
H73 Other disorders of tympanic membrane	0.015	0.985	0.000
H74 Other disorders of middle ear and mastoid	0.015	0.985	0.000
H71 Cholesteatoma of middle ear	0.015	0.985	0.000
H72.1 Attic perforation of tympanic membrane	0.015	0.985	0.000
H81.9 Disorder of vestibular function, unspecified	0.014	0.986	0.000
H81.8 Other disorders of vestibular function	0.014	0.986	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.014	0.986	0.000
H81.3 Other peripheral vertigo	0.014	0.986	0.000
H70.9 Mastoiditis, unspecified	0.014	0.986	0.000
H83 Other diseases of inner ear	0.013	0.986	0.000
H69 Other disorders of Eustachian tube	0.013	0.987	0.000
H81.4 Vertigo of central origin	0.013	0.987	0.000
H74.0 Tympanosclerosis	0.013	0.987	0.000
H93.2 Other abnormal auditory perceptions	0.013	0.987	0.000
H70.8 Other mastoiditis and related conditions	0.013	0.987	0.000
H93.0 Degenerative and vascular disorders of ear	0.013	0.987	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.012	0.987	0.000
H93.3 Disorders of acoustic nerve	0.012	0.987	0.000
H70.2 Petrositis	0.012	0.987	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.012	0.987	0.000
H70.0 Acute mastoiditis	0.012	0.987	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.012	0.987	0.000
H80 Otosclerosis	0.012	0.988	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.012	0.988	0.000
H72.2 Other marginal perforations of tympanic membrane	0.012	0.988	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.012	0.988	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.012	0.988	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.012	0.988	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.012	0.988	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.012	0.988	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.012	0.988	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.012	0.988	0.000
H81.2 Vestibular neuronitis	0.012	0.988	0.000
H90 Conductive and sensorineural hearing loss	0.012	0.988	0.000
H70.1 Chronic mastoiditis	0.012	0.988	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.012	0.988	0.000
H68.0 Eustachian salpingitis	0.012	0.988	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.011	0.989	0.000
H68.1 Obstruction of Eustachian tube	0.011	0.989	0.000
H73.8 Other specified disorders of tympanic membrane	0.011	0.989	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.011	0.989	0.000
H83.0 Labyrinthitis	0.011	0.989	0.000
H73.0 Acute myringitis	0.011	0.989	0.000
H93.8 Other specified disorders of ear	0.010	0.989	0.000
H93.9 Disorder of ear, unspecified	0.010	0.989	0.000
H95.1 Other disorders following mastoidectomy	0.010	0.989	0.000
H73.1 Chronic myringitis	0.010	0.990	0.000
H66 Suppurative and unspecified otitis media	0.010	0.990	0.000
H83.2 Labyrinthine dysfunction	0.010	0.990	0.000
H74.4 Polyp of middle ear	0.010	0.990	0.000
H83.1 Labyrinthine fistula	0.010	0.990	0.000
H69.0 Patulous Eustachian tube	0.010	0.990	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.010	0.990	0.000
H83.3 Noise effects on inner ear	0.009	0.990	0.000
O36 Maternal care for other known or suspected foetal problems	0.010	0.990	0.000
H90.0 Conductive hearing loss, bilateral	0.009	0.990	0.000
R42 Dizziness and giddiness	0.010	0.990	0.000
H60-H62 Diseases of external ear	0.009	0.990	0.000
H80.8 Other otosclerosis	0.009	0.991	0.000
O36.8 Maternal care for other specified foetal problems	0.009	0.991	0.000
H83.8 Other specified diseases of inner ear	0.009	0.991	0.000
H80.2 Cochlear otosclerosis	0.009	0.991	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.009	0.991	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.009	0.991	0.000
H92 Otalgia and effusion of ear	0.008	0.991	0.001
H83.9 Disease of inner ear, unspecified	0.009	0.991	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.009	0.991	0.000
H69.8 Other specified disorders of Eustachian tube	0.008	0.991	0.000
O36.5 Maternal care for poor foetal growth	0.009	0.991	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.008	0.991	0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.009	0.991	0.000
H74.1 Adhesive middle ear disease	0.008	0.992	0.001
H90.3 Sensorineural hearing loss, bilateral	0.008	0.992	0.000
H69.9 Eustachian tube disorder, unspecified	0.008	0.992	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.008	0.992	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.008	0.992	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.008	0.992	0.001
O36.3 Maternal care for signs of foetal hypoxia	0.008	0.992	0.000
H66.4 Suppurative otitis media, unspecified	0.008	0.992	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.008	0.992	0.000
H80.9 Otosclerosis, unspecified	0.008	0.992	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.008	0.992	0.000
O44 Placenta praevia	0.008	0.992	0.000
H90.5 Sensorineural hearing loss, unspecified	0.007	0.992	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.007	0.992	0.000
O36.1 Maternal care for other isoimmunisation	0.008	0.992	0.000
H66.0 Acute suppurative otitis media	0.007	0.992	0.000
O36.4 Maternal care for intra-uterine death	0.008	0.992	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.007	0.993	0.000
O26.8 Other specified pregnancy-related conditions	0.007	0.993	0.000
O42 Premature rupture of membranes	0.007	0.993	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.007	0.993	0.000
O36.2 Maternal care for hydrops foetalis	0.007	0.993	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.007	0.993	0.000
O44.1 Placenta praevia with haemorrhage	0.007	0.993	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.007	0.993	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.007	0.993	0.000
N35.9 Urethral stricture, unspecified	0.007	0.993	0.000
O43 Placental disorders	0.007	0.993	0.000
H90.2 Conductive hearing loss, unspecified	0.006	0.993	0.000
O36.6 Maternal care for excessive foetal growth	0.007	0.993	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.007	0.993	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.007	0.993	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.006	0.993	0.000
O20 Haemorrhage in early pregnancy	0.006	0.993	0.000
O45 Premature separation of placenta [abruptio placentae]	0.006	0.994	0.000
O31 Complications specific to multiple gestation	0.006	0.994	0.000
O33 Maternal care for known or suspected disproportion	0.006	0.994	0.000
H92.2 Otorrhagia	0.006	0.994	0.001
O35 Maternal care for known or suspected foetal abnormality and damage	0.006	0.994	0.000
L60.0 Ingrowing nail	0.006	0.994	0.000
H66.9 Otitis media, unspecified	0.006	0.994	0.000
O41 Other disorders of amniotic fluid and membranes	0.006	0.994	0.000
O20.0 Threatened abortion	0.006	0.994	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.006	0.994	0.000
I42.0 Dilated cardiomyopathy	0.006	0.994	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.994	0.006
O47 False labour	0.006	0.994	0.000
O36.9 Maternal care for foetal problem, unspecified	0.006	0.994	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.006	0.994	0.000
O46.9 Antepartum haemorrhage, unspecified	0.006	0.994	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O21 Excessive vomiting in pregnancy	0.006	0.994	0.000
O46.8 Other antepartum haemorrhage	0.006	0.994	0.000
O42.9 Premature rupture of membranes, unspecified	0.006	0.994	0.000
O30 Multiple gestation	0.006	0.994	0.000
O20.8 Other haemorrhage in early pregnancy	0.006	0.994	0.000
O43.1 Malformation of placenta	0.005	0.994	0.000
I42.9 Cardiomyopathy, unspecified	0.005	0.995	0.000
O43.9 Placental disorder, unspecified	0.005	0.995	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.005	0.995	0.000
O28 Abnormal findings on antenatal screening of mother	0.005	0.995	0.000
O43.0 Placental transfusion syndromes	0.005	0.995	0.000
I42 Cardiomyopathy	0.005	0.995	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.005	0.995	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.005	0.995	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.005	0.995	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
H62.2 Otitis externa in mycoses	0.005	0.995	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.005	0.995	0.000
H60 Otitis externa	0.005	0.995	0.000
O45.9 Premature separation of placenta, unspecified	0.005	0.995	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.005	0.995	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.005	0.995	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.005	0.995	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.005	0.995	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.005	0.995	0.000
O31.8 Other complications specific to multiple gestation	0.005	0.995	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.005	0.995	0.000
O41.0 Oligohydramnios	0.005	0.995	0.000
O43.2 Morbidly adherent placenta	0.005	0.995	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.005	0.995	0.000
O47.9 False labour, unspecified	0.005	0.995	0.000
L91.8 Other hypertrophic disorders of skin	0.005	0.995	0.000
O26.0 Excessive weight gain in pregnancy	0.005	0.995	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.005	0.995	0.000
O21.9 Vomiting of pregnancy, unspecified	0.005	0.995	0.000
O29 Complications of anaesthesia during pregnancy	0.005	0.995	0.000
O25 Malnutrition in pregnancy	0.005	0.995	0.000
O33.9 Maternal care for disproportion, unspecified	0.005	0.995	0.000
O26.4 Herpes gestationis	0.005	0.995	0.000
O26.1 Low weight gain in pregnancy	0.005	0.995	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.005	0.995	0.000
O31.0 Papyraceous foetus	0.005	0.995	0.000
O45.8 Other premature separation of placenta	0.005	0.995	0.000
O45.0 Premature separation of placenta with coagulation defect	0.005	0.995	0.000
O33.8 Maternal care for disproportion of other origin	0.005	0.995	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.005	0.995	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.005	0.995	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.005	0.995	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.005	0.995	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.005	0.995	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.005	0.995	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.005	0.995	0.000
O26.2 Pregnancy care of habitual aborter	0.005	0.995	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.005	0.995	0.000
O21.2 Late vomiting of pregnancy	0.005	0.995	0.000
H61 Other disorders of external ear	0.004	0.995	0.000
I42.2 Other hypertrophic cardiomyopathy	0.005	0.995	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.005	0.995	0.000
H66.3 Other chronic suppurative otitis media	0.004	0.995	0.001
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.005	0.995	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.005	0.995	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.005	0.995	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.005	0.995	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.005	0.995	0.000
O26.5 Maternal hypotension syndrome	0.005	0.995	0.000
O48 Prolonged pregnancy	0.005	0.995	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.005	0.995	0.000
O24 Diabetes mellitus in pregnancy	0.005	0.995	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.004	0.995	0.000
O41.1 Infection of amniotic sac and membranes	0.004	0.995	0.000
O40 Polyhydramnios	0.004	0.995	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.004	0.995	0.000
O21.0 Mild hyperemesis gravidarum	0.004	0.995	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.004	0.995	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.004	0.995	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.004	0.995	0.000
O43.8 Other placental disorders	0.004	0.995	0.000
O15 Eclampsia	0.004	0.995	0.000
O16 Unspecified maternal hypertension	0.005	0.995	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.004	0.995	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.004	0.995	0.000
H92.0 Otalgia	0.004	0.995	0.001
O14.0 Moderate preeclampsia	0.004	0.995	0.000
H92.1 Otorrhoea	0.004	0.995	0.001
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.996	0.004
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.004	0.996	0.000
O30.1 Triplet pregnancy	0.004	0.996	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.004	0.996	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.004	0.996	0.000
O30.9 Multiple gestation, unspecified	0.004	0.996	0.000
O30.8 Other multiple gestation	0.004	0.996	0.000
O30.2 Quadruplet pregnancy	0.004	0.996	0.000
O32.0 Maternal care for unstable lie	0.004	0.996	0.000
O14.1 Severe preeclampsia	0.004	0.996	0.000
C79 Secondary malignant neoplasm of other sites	0.000	0.996	0.004
O22 Venous complications in pregnancy	0.004	0.996	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.996	0.004
I42.6 Alcoholic cardiomyopathy	0.004	0.996	0.000
I42.4 Endocardial fibroelastosis	0.004	0.996	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.004	0.996	0.000
H61.8 Other specified disorders of external ear	0.004	0.996	0.000
I42.5 Other restrictive cardiomyopathy	0.004	0.996	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.004	0.996	0.000
H60.3 Other infective otitis externa	0.004	0.996	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.004	0.996	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.004	0.996	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.004	0.996	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.004	0.996	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.996	0.004
I42.3 Endomyocardial (eosinophilic) disease	0.004	0.996	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.004	0.996	0.000
O21.8 Other vomiting complicating pregnancy	0.004	0.996	0.000
H60.1 Cellulitis of external ear	0.004	0.996	0.000
O32.6 Maternal care for compound presentation	0.004	0.996	0.000
K26 Duodenal ulcer	0.004	0.996	0.000
O14.2 HELLP syndrome	0.004	0.996	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.004	0.996	0.000
H60.2 Malignant otitis externa	0.004	0.996	0.000
O32.4 Maternal care for high head at term	0.004	0.996	0.000
O80-O84 Delivery	0.004	0.996	0.000
H60.9 Otitis externa, unspecified	0.004	0.996	0.000
O32.3 Maternal care for face, brow and chin presentation	0.004	0.996	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.004	0.996	0.000
H60.4 Cholesteatoma of external ear	0.004	0.996	0.000
H60.0 Abscess of external ear	0.004	0.996	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.004	0.996	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.004	0.996	0.000
O29.6 Failed or difficult intubation during pregnancy	0.004	0.996	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.004	0.996	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.004	0.996	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.004	0.996	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.004	0.996	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.004	0.996	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.004	0.996	0.000
O23 Infections of genito-urinary tract in pregnancy	0.004	0.996	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.004	0.996	0.000
O30.0 Twin pregnancy	0.004	0.996	0.000
O32.8 Maternal care for other malpresentation of foetus	0.004	0.996	0.000
H61.9 Disorder of external ear, unspecified	0.003	0.996	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.004	0.996	0.000
O32.2 Maternal care for transverse and oblique lie	0.004	0.996	0.000
O97 Death from sequelae of direct obstetric causes	0.004	0.996	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.004	0.996	0.000
O95 Obstetric death of unspecified cause	0.004	0.996	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O14.9 Preeclampsia, unspecified	0.004	0.996	0.000
C79.6 Secondary malignant neoplasm of ovary	0.000	0.996	0.004
H60.5 Acute otitis externa, non-infective	0.003	0.996	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.003	0.996	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.003	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations