TreeWAS – Variant ID: rs6532197

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G20 Parkinson's disease	0.168	0.832	0.000
G20-G26 Extrapyramidal and movement disorders	0.079	0.921	0.000
G24 Dystonia	0.072	0.928	0.000
G24.9 Dystonia, unspecified	0.066	0.934	0.000
G24.8 Other dystonia	0.058	0.942	0.000
G23 Other degenerative diseases of basal ganglia	0.057	0.943	0.000
G21 Secondary Parkinsonism	0.057	0.943	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.057	0.943	0.000
G22 Parkinsonism in diseases classified elsewhere	0.057	0.943	0.000
G24.4 Idiopathic orofacial dystonia	0.052	0.948	0.000
G24.3 Spasmodic torticollis	0.052	0.948	0.000
G24.2 Idiopathic nonfamilial dystonia	0.052	0.948	0.000
G24.1 Idiopathic familial dystonia	0.052	0.948	0.000
G24.0 Drug-induced dystonia	0.052	0.948	0.000
G24.5 Blepharospasm	0.050	0.950	0.000
G21.9 Secondary Parkinsonism, unspecified	0.041	0.959	0.000
G21.8 Other secondary Parkinsonism	0.041	0.959	0.000
G21.4 Vascular parkinsonism	0.041	0.959	0.000
G21.3 Postencephalitic Parkinsonism	0.041	0.959	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.041	0.959	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.041	0.959	0.000
G21.0 Malignant neuroleptic syndrome	0.041	0.959	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.041	0.959	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.041	0.959	0.000
G23.3 Multiple system atrophy, cerebellar type	0.041	0.959	0.000
G23.2 Striatonigral degeneration	0.041	0.959	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.041	0.959	0.000
G23.0 Hallervorden-Spatz disease	0.041	0.959	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.032	0.968	0.000
G25 Other extrapyramidal and movement disorders	0.021	0.977	0.001
N60.1 Diffuse cystic mastopathy	0.022	0.978	0.000
N60 Benign mammary dysplasia	0.021	0.979	0.000
N60.8 Other benign mammary dysplasias	0.021	0.979	0.000
N60.0 Solitary cyst of breast	0.019	0.981	0.000
N60.3 Fibrosclerosis of breast	0.018	0.982	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.015	0.983	0.001
G25.6 Drug-induced tics and other tics of organic origin	0.015	0.983	0.001
G25.5 Other chorea	0.015	0.983	0.001
G25.4 Drug-induced chorea	0.015	0.983	0.001
G25.2 Other specified forms of tremor	0.015	0.983	0.001
G25.1 Drug-induced tremor	0.015	0.983	0.001
N60.4 Mammary duct ectasia	0.015	0.984	0.000
N60.9 Benign mammary dysplasia, unspecified	0.015	0.985	0.000
N60.2 Fibroadenosis of breast	0.015	0.985	0.000
G25.3 Myoclonus	0.014	0.985	0.001
K41 Femoral hernia	0.013	0.987	0.000
C44.2 Skin of ear and external auricular canal	0.000	0.987	0.013
C91.1 Chronic lymphocytic leukaemia	0.010	0.990	0.000
G25.0 Essential tremor	0.008	0.990	0.002
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.010	0.990	0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.010	0.990	0.000
K41.1 Bilateral femoral hernia, with gangrene	0.010	0.990	0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.010	0.990	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.009	0.990	0.000
C91 Lymphoid leukaemia	0.009	0.991	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.007	0.991	0.002
C83.3 Large cell (diffuse)	0.008	0.992	0.000
C91.0 Acute lymphoblastic leukaemia	0.008	0.992	0.000
C91.4 Hairy-cell leukaemia	0.008	0.992	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.007	0.993	0.000
C91.9 Lymphoid leukaemia, unspecified	0.007	0.993	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.007	0.993	0.000
C91.7 Other lymphoid leukaemia	0.007	0.993	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.007	0.993	0.000
C91.5 Adult T-cell leukaemia	0.007	0.993	0.000
C91.3 Prolymphocytic leukaemia	0.007	0.993	0.000
C91.2 Subacute lymphocytic leukaemia	0.007	0.993	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.007	0.993	0.000
H91.9 Hearing loss, unspecified	0.007	0.993	0.000
H43.8 Other disorders of vitreous body	0.000	0.994	0.006
H91 Other hearing loss	0.006	0.994	0.000
C93 Monocytic leukaemia	0.006	0.994	0.000
H43 Disorders of vitreous body	0.000	0.994	0.006
H33.3 Retinal breaks without detachment	0.000	0.994	0.006
C84 Peripheral and cutaneous T-cell lymphomas	0.006	0.994	0.000
H43.1 Vitreous haemorrhage	0.000	0.994	0.006
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.005	0.995	0.000
C83.7 Burkitt's tumour	0.005	0.995	0.000
C83.6 Undifferentiated (diffuse)	0.005	0.995	0.000
C83.5 Lymphoblastic (diffuse)	0.005	0.995	0.000
C83.4 Immunoblastic (diffuse)	0.005	0.995	0.000
C83.2 Mixed small and large cell (diffuse)	0.005	0.995	0.000
H90-H95 Other disorders of ear	0.005	0.995	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.005	0.995	0.000
C93.1 Chronic monocytic leukaemia	0.005	0.995	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.005	0.995	0.000
C95 Leukaemia of unspecified cell type	0.005	0.995	0.000
C94 Other leukaemias of specified cell type	0.005	0.995	0.000
C86 Other specified types of T/NK-cell lymphoma	0.005	0.995	0.000
H93 Other disorders of ear, not elsewhere classified	0.005	0.995	0.000
C83.0 Small cell (diffuse)	0.005	0.995	0.000
C83.1 Small cleaved cell (diffuse)	0.005	0.995	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.005	0.995	0.000
C88 Malignant immunoproliferative diseases	0.005	0.995	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.005	0.995	0.000
H91.3 Deaf mutism, not elsewhere classified	0.005	0.995	0.000
C84.0 Mycosis fungoides	0.005	0.995	0.000
H93.1 Tinnitus	0.005	0.995	0.000
C92 Myeloid leukaemia	0.005	0.995	0.000
C85.1 B-cell lymphoma, unspecified	0.005	0.995	0.000
C84.4 Peripheral T-cell lymphoma	0.004	0.995	0.000
H91.2 Sudden idiopathic hearing loss	0.004	0.995	0.000
H91.1 Presbycusis	0.004	0.995	0.000
H91.0 Ototoxic hearing loss	0.004	0.995	0.000
H91.8 Other specified hearing loss	0.004	0.995	0.000
C93.9 Monocytic leukaemia, unspecified	0.004	0.996	0.000
C93.7 Other monocytic leukaemia	0.004	0.996	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.004	0.996	0.000
C93.2 Subacute monocytic leukaemia	0.004	0.996	0.000
C93.0 Acute monocytic leukaemia	0.004	0.996	0.000
C81 Hodgkin's disease	0.004	0.996	0.000
H93.8 Other specified disorders of ear	0.004	0.996	0.000
H44.2 Degenerative myopia	0.000	0.996	0.004
H43.9 Disorder of vitreous body, unspecified	0.000	0.996	0.004
H43.2 Crystalline deposits in vitreous body	0.000	0.996	0.004
H43.0 Vitreous prolapse	0.000	0.996	0.004
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.004	0.996	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.004	0.996	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.004	0.996	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.004	0.996	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.004	0.996	0.000
C84.3 Lymphoepithelioid lymphoma	0.004	0.996	0.000
C84.2 T-zone lymphoma	0.004	0.996	0.000
C84.1 Sezary's diease	0.004	0.996	0.000
H33.0 Retinal detachment with retinal break	0.000	0.996	0.004
H33 Retinal detachments and breaks	0.000	0.996	0.004
H92 Otalgia and effusion of ear	0.004	0.996	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.004	0.996	0.000
H90 Conductive and sensorineural hearing loss	0.004	0.996	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.004	0.996	0.000
N20.0 Calculus of kidney	0.000	0.996	0.004
H44 Disorders of globe	0.000	0.996	0.004
H94 Other disorders of ear in diseases classified elsewhere	0.004	0.996	0.000
C44.5 Skin of trunk	0.000	0.996	0.004
H43.3 Other vitreous opacities	0.000	0.996	0.004
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.004	0.996	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.004	0.996	0.000
C86.4 Blastic NK-cell lymphoma	0.004	0.996	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.004	0.996	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.004	0.996	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.004	0.996	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.004	0.996	0.000
C94.7 Other specified leukaemias	0.004	0.996	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.004	0.996	0.000
C94.5 Acute myelofibrosis	0.004	0.996	0.000
C94.4 Acute panmyelosis	0.004	0.996	0.000
C94.3 Mast cell leukaemia	0.004	0.996	0.000
C94.2 Acute megakaryoblastic leukaemia	0.004	0.996	0.000
C94.1 Chronic erythraemia	0.004	0.996	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.004	0.996	0.000
C95.9 Leukaemia, unspecified	0.004	0.996	0.000
C95.7 Other leukaemia of unspecified cell type	0.004	0.996	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.004	0.996	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.004	0.996	0.000
C95.0 Acute leukaemia of unspecified cell type	0.004	0.996	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.004	0.996	0.000
C96.8 Histiocytic sarcoma	0.004	0.996	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.004	0.996	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.004	0.996	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.004	0.996	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.004	0.996	0.000
C96.3 True histiocytic lymphoma	0.004	0.996	0.000
C96.2 Malignant mast cell tumour	0.004	0.996	0.000
C96.1 Malignant histiocytosis	0.004	0.996	0.000
C96.0 Letterer-Siwe disease	0.004	0.996	0.000
H93.9 Disorder of ear, unspecified	0.004	0.996	0.000
H93.3 Disorders of acoustic nerve	0.004	0.996	0.000
H93.2 Other abnormal auditory perceptions	0.004	0.996	0.000
H93.0 Degenerative and vascular disorders of ear	0.004	0.996	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.004	0.996	0.000
C85.0 Lymphosarcoma	0.004	0.996	0.000
I73.9 Peripheral vascular disease, unspecified	0.004	0.996	0.000
H43-H45 Disorders of vitreous body and globe	0.000	0.996	0.004
C84.5 Other and unspecified T-cell lymphomas	0.004	0.996	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.004	0.996	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.004	0.996	0.000
C88.7 Other malignant immunoproliferative diseases	0.004	0.996	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.004	0.996	0.000
C88.3 Immunoproliferative small intestinal disease	0.004	0.996	0.000
C88.2 Gamma heavy chain disease	0.004	0.996	0.000
C88.1 Alpha heavy chain disease	0.004	0.996	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.004	0.996	0.000
C44 Other malignant neoplasms of skin	0.000	0.996	0.004
C82.6 Cutaneous follicle centre lymphoma	0.004	0.996	0.000
C82.5 Diffuse follicle centre lymphoma	0.004	0.996	0.000
C82.4 Follicular lymphoma grade IIIb	0.004	0.996	0.000
C82.3 Follicular lymphoma grade IIIa	0.004	0.996	0.000
C82.2 Large cell, follicular	0.004	0.996	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.004	0.996	0.000
C82.0 Small cleaved cell, follicular	0.004	0.996	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.004	0.996	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.996	0.004
H33.2 Serous retinal detachment	0.000	0.996	0.004
C92.9 Myeloid leukaemia, unspecified	0.003	0.996	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.003	0.996	0.000
C92.7 Other myeloid leukaemia	0.003	0.996	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.003	0.996	0.000
C92.5 Acute myelomonocytic leukaemia	0.003	0.996	0.000
C92.4 Acute promyelocytic leukaemia	0.003	0.996	0.000
C92.3 Myeloid sarcoma	0.003	0.996	0.000
C92.2 Subacute myeloid leukaemia	0.003	0.996	0.000
H90.0 Conductive hearing loss, bilateral	0.004	0.996	0.000
N20.1 Calculus of ureter	0.000	0.996	0.004
H90.5 Sensorineural hearing loss, unspecified	0.004	0.996	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.004	0.996	0.000
C44.7 Skin of lower limb, including hip	0.000	0.996	0.004
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.003	0.996	0.000
C92.1 Chronic myeloid leukaemia	0.003	0.996	0.000
C44.0 Skin of lip	0.000	0.996	0.003
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.003	0.996	0.000
C90.2 Plasmacytoma, extramedullary	0.003	0.997	0.000
H92.0 Otalgia	0.003	0.997	0.000
C81.7 Other Hodgkin's disease	0.003	0.997	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.003	0.997	0.000
C81.3 Lymphocytic depletion	0.003	0.997	0.000
C81.2 Mixed cellularity	0.003	0.997	0.000
C81.0 Lymphocytic predominance	0.003	0.997	0.000
K74.5 Biliary cirrhosis, unspecified	0.003	0.997	0.000
H33.5 Other retinal detachments	0.000	0.997	0.003
K74.3 Primary biliary cirrhosis	0.003	0.997	0.000
H92.1 Otorrhoea	0.003	0.997	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.003	0.997	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.003	0.997	0.000
N20 Calculus of kidney and ureter	0.000	0.997	0.003
C81.1 Nodular sclerosis	0.003	0.997	0.000
D68.9 Coagulation defect, unspecified	0.000	0.997	0.003
H92.2 Otorrhagia	0.003	0.997	0.000
C90.3 Solitary plasmacytoma	0.003	0.997	0.000
C90.1 Plasma cell leukaemia	0.003	0.997	0.000
C92.0 Acute myeloid leukaemia	0.003	0.997	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.003	0.997	0.000
H33.1 Retinoschisis and retinal cysts	0.000	0.997	0.003
D68 Other coagulation defects	0.000	0.997	0.003
H44.9 Disorder of globe, unspecified	0.000	0.997	0.003
H44.8 Other disorders of globe	0.000	0.997	0.003
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.000	0.997	0.003
H44.6 Retained (old) intraocular foreign body, magnetic	0.000	0.997	0.003
H44.5 Degenerated conditions of globe	0.000	0.997	0.003
H44.4 Hypotony of eye	0.000	0.997	0.003
H44.3 Other degenerative disorders of globe	0.000	0.997	0.003
H44.1 Other endophthalmitis	0.000	0.997	0.003
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.003	0.997	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H44.0 Purulent endophthalmitis	0.000	0.997	0.003
H33.4 Traction detachment of retina	0.000	0.997	0.003
K74 Fibrosis and cirrhosis of liver	0.003	0.997	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.003	0.997	0.000
I77.6 Arteritis, unspecified	0.003	0.997	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.997	0.003
H95.1 Other disorders following mastoidectomy	0.003	0.997	0.000
I77 Other disorders of arteries and arterioles	0.003	0.997	0.000
D68.8 Other specified coagulation defects	0.000	0.997	0.003
C44.8 Overlapping lesion of skin	0.000	0.997	0.003
K85.9 Acute pancreatitis, unspecified	0.003	0.997	0.000
I73 Other peripheral vascular diseases	0.003	0.997	0.000
D68.0 Von Willebrand's disease	0.000	0.997	0.003
H90.3 Sensorineural hearing loss, bilateral	0.003	0.997	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
N20.2 Calculus of kidney with calculus of ureter	0.000	0.997	0.003
I74 Arterial embolism and thrombosis	0.003	0.997	0.000
C81.9 Hodgkin's disease, unspecified	0.003	0.997	0.000
K74.0 Hepatic fibrosis	0.003	0.997	0.000
N20.9 Urinary calculus, unspecified	0.000	0.997	0.003
B34.9 Viral infection, unspecified	0.003	0.997	0.000
D68.6 Other Thrombophilia	0.000	0.997	0.003
I70-I79 Diseases of arteries, arterioles and capillaries	0.003	0.997	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.997	0.003
H66.9 Otitis media, unspecified	0.000	0.997	0.003
K74.6 Other and unspecified cirrhosis of liver	0.003	0.997	0.000
D68.5 Primary Thrombophilia	0.000	0.997	0.003
I74.5 Embolism and thrombosis of iliac artery	0.003	0.997	0.000
I77.8 Other specified disorders of arteries and arterioles	0.003	0.997	0.000
H72 Perforation of tympanic membrane	0.003	0.997	0.000
I73.8 Other specified peripheral vascular diseases	0.003	0.997	0.000
I74.8 Embolism and thrombosis of other arteries	0.003	0.997	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.997	0.002
D68.1 Hereditary factor XI deficiency	0.000	0.997	0.002
H72.0 Central perforation of tympanic membrane	0.003	0.997	0.000
K74.4 Secondary biliary cirrhosis	0.002	0.997	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.002	0.997	0.000
K74.1 Hepatic sclerosis	0.002	0.997	0.000
H40.2 Primary angle-closure glaucoma	0.003	0.997	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.997	0.002
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.997	0.002
H45.1 Endophthalmitis in diseases classified elsewhere	0.000	0.997	0.002
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.000	0.997	0.002
Z85.6 Personal history of leukaemia	0.003	0.997	0.000
H71 Cholesteatoma of middle ear	0.002	0.997	0.000
Chapter VIII Diseases of the ear and mastoid process	0.003	0.997	0.000
I77.5 Necrosis of artery	0.002	0.997	0.000
I77.4 Coeliac artery compression syndrome	0.002	0.997	0.000
I77.3 Arterial fibromuscular dysplasia	0.002	0.997	0.000
I77.2 Rupture of artery	0.002	0.997	0.000
I77.0 Arteriovenous fistula, acquired	0.002	0.997	0.000
I70 Atherosclerosis	0.002	0.997	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.000	0.998	0.002
H72.9 Perforation of tympanic membrane, unspecified	0.002	0.998	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.002	0.998	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.002	0.998	0.000
H65-H75 Diseases of middle ear and mastoid	0.002	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.002	0.998	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.002	0.998	0.000
D45 Polycythaemia vera	0.000	0.998	0.002
S52.00 Fracture of upper end of ulna (closed)	0.002	0.998	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.002	0.998	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.002	0.998	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.002	0.998	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.998	0.002
I70.0 Atherosclerosis of aorta	0.002	0.998	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.002	0.998	0.000
I71 Aortic aneurysm and dissection	0.002	0.998	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.002	0.998	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.002	0.998	0.000
K13.0 Diseases of lips	0.000	0.998	0.002
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.998	0.002
C44.4 Skin of scalp and neck	0.000	0.998	0.002
K85.3 Drug-induced acute pancreatitis	0.002	0.998	0.000
K85 Acute pancreatitis	0.002	0.998	0.000
H40.1 Primary open-angle glaucoma	0.002	0.998	0.000
H72.2 Other marginal perforations of tympanic membrane	0.002	0.998	0.000
H72.1 Attic perforation of tympanic membrane	0.002	0.998	0.000
H69 Other disorders of Eustachian tube	0.002	0.998	0.000
H90.2 Conductive hearing loss, unspecified	0.002	0.998	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.002	0.998	0.000
H72.8 Other perforations of tympanic membrane	0.002	0.998	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.002	0.998	0.000
F20.9 Schizophrenia, unspecified	0.000	0.998	0.002
I70.9 Generalised and unspecified atherosclerosis	0.002	0.998	0.000
I70.8 Atherosclerosis of other arteries	0.002	0.998	0.000
I70.1 Atherosclerosis of renal artery	0.002	0.998	0.000
F20.0 Paranoid schizophrenia	0.000	0.998	0.002
C90.0 Multiple myeloma	0.002	0.998	0.000
I79.1 Aortitis in diseases classified elsewhere	0.002	0.998	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.002	0.998	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.998	0.002
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.998	0.000
H68 Eustachian salpingitis and obstruction	0.002	0.998	0.000
H67 Otitis media in diseases classified elsewhere	0.002	0.998	0.000
H66 Suppurative and unspecified otitis media	0.001	0.998	0.001
Q21.1 Atrial septal defect	0.000	0.998	0.002
K42.9 Umbilical hernia without obstruction or gangrene	0.000	0.998	0.002
H70 Mastoiditis and related conditions	0.002	0.998	0.000
H80-H83 Diseases of inner ear	0.002	0.998	0.000
H69.9 Eustachian tube disorder, unspecified	0.002	0.998	0.000
H81.0 Meniere's disease	0.002	0.998	0.000
Z04.3 Examination and observation following other accident	0.002	0.998	0.000
F20 Schizophrenia	0.000	0.998	0.002
K85.8 Other acute pancreatitis	0.002	0.998	0.000
M41.9 Scoliosis, unspecified	0.000	0.998	0.002
K13 Other diseases of lip and oral mucosa	0.000	0.998	0.002
K80.4 Calculus of bile duct with cholecystitis	0.002	0.998	0.000
K85.2 Alcohol-induced acute pancreatitis	0.002	0.998	0.000
H40 Glaucoma	0.002	0.998	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.002	0.998	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.002	0.998	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.002	0.998	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.002	0.998	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.002	0.998	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.002	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.002	0.998	0.000
H40.3 Glaucoma secondary to eye trauma	0.002	0.998	0.000
H69.8 Other specified disorders of Eustachian tube	0.002	0.998	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.002	0.998	0.000
I72 Other aneurysm	0.002	0.998	0.000
N43.3 Hydrocele, unspecified	0.000	0.998	0.002
I71.3 Abdominal aortic aneurysm, ruptured	0.002	0.998	0.000
I77.1 Stricture of artery	0.002	0.998	0.000
K85.0 Idiopathic acute pancreatitis	0.002	0.998	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.002	0.998	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.002	0.998	0.000
H69.0 Patulous Eustachian tube	0.002	0.998	0.000
H73 Other disorders of tympanic membrane	0.002	0.998	0.000
I71.0 Dissection of aorta [any part]	0.002	0.998	0.000
H80 Otosclerosis	0.002	0.998	0.000
H40.0 Glaucoma suspect	0.002	0.998	0.000
H66.0 Acute suppurative otitis media	0.001	0.998	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.001	0.998	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.001	0.998	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.001	0.998	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.001	0.998	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.001	0.998	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.001	0.998	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.998	0.002
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.002	0.998	0.000
H81 Disorders of vestibular function	0.002	0.998	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.001	0.998	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.001	0.998	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.001	0.998	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.001	0.998	0.000
H68.1 Obstruction of Eustachian tube	0.001	0.998	0.000
H68.0 Eustachian salpingitis	0.001	0.998	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.001	0.998	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.002	0.998	0.000
H66.4 Suppurative otitis media, unspecified	0.001	0.998	0.001
H66.2 Chronic atticoantral suppurative otitis media	0.001	0.998	0.001
H80.9 Otosclerosis, unspecified	0.002	0.998	0.000
K11.2 Sialoadenitis	0.000	0.998	0.002
K85.1 Biliary acute pancreatitis	0.002	0.998	0.000
H74 Other disorders of middle ear and mastoid	0.002	0.998	0.000
I78 Diseases of capillaries	0.002	0.998	0.000
H60-H62 Diseases of external ear	0.002	0.998	0.000
H40.8 Other glaucoma	0.002	0.998	0.000
H60.1 Cellulitis of external ear	0.002	0.998	0.000
H70.8 Other mastoiditis and related conditions	0.001	0.998	0.000
H70.2 Petrositis	0.001	0.998	0.000
H70.1 Chronic mastoiditis	0.001	0.998	0.000
H70.0 Acute mastoiditis	0.001	0.998	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.002	0.998	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.998	0.002
F20.8 Other schizophrenia	0.000	0.998	0.002
F20.6 Simple schizophrenia	0.000	0.998	0.002
F20.5 Residual schizophrenia	0.000	0.998	0.002
F20.4 Postschizophrenic depression	0.000	0.998	0.002
F20.3 Undifferentiated schizophrenia	0.000	0.998	0.002
F20.2 Catatonic schizophrenia	0.000	0.998	0.002
F20.1 Hebephrenic schizophrenia	0.000	0.998	0.002
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.001
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.000	0.998	0.001
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.998	0.001
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.000	0.998	0.001
M41.92 Scoliosis, unspecified (Cervical region)	0.000	0.998	0.001
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.001
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.000	0.998	0.001
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.998	0.002
A08.4 Viral intestinal infection, unspecified	0.002	0.998	0.000
H40.6 Glaucoma secondary to drugs	0.002	0.998	0.000
H40.4 Glaucoma secondary to eye inflammation	0.002	0.998	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.000	0.998	0.002
K13.5 Oral submucous fibrosis	0.000	0.998	0.002
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.000	0.998	0.002
K13.3 Hairy leukoplakia	0.000	0.998	0.002
K13.1 Cheek and lip biting	0.000	0.998	0.002
H60 Otitis externa	0.002	0.998	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.002	0.998	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
H73.9 Disorder of tympanic membrane, unspecified	0.001	0.998	0.000
K11.5 Sialolithiasis	0.000	0.998	0.002
F22.0 Delusional disorder	0.000	0.998	0.002
H70.9 Mastoiditis, unspecified	0.001	0.998	0.000
Y85.0 Sequelae of motor-vehicle accident	0.000	0.998	0.002
I72.9 Aneurysm of unspecified site	0.001	0.998	0.000
I72.8 Aneurysm of other specified arteries	0.001	0.998	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.001	0.998	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.001	0.998	0.000
I72.2 Aneurysm of renal artery	0.001	0.998	0.000
I72.1 Aneurysm of artery of upper extremity	0.001	0.998	0.000
H60.3 Other infective otitis externa	0.001	0.998	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.000	0.998	0.001
D66 Hereditary factor VIII deficiency	0.000	0.998	0.002
S42.10 Fracture of scapula (closed)	0.000	0.998	0.002
H73.1 Chronic myringitis	0.001	0.998	0.000
H73.0 Acute myringitis	0.001	0.998	0.000
H80.8 Other otosclerosis	0.001	0.998	0.000
H80.2 Cochlear otosclerosis	0.001	0.998	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.001	0.998	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.001	0.998	0.000
M25.84 Other specified joint disorders (Hand)	0.002	0.998	0.000
I46.9 Cardiac arrest, unspecified	0.002	0.998	0.000
I72.0 Aneurysm of carotid artery	0.001	0.998	0.000
K12.1 Other forms of stomatitis	0.000	0.998	0.002
G00 Bacterial meningitis, not elsewhere classified	0.001	0.998	0.000
H81.9 Disorder of vestibular function, unspecified	0.001	0.998	0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.001	0.998	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.001	0.998	0.000
H81.8 Other disorders of vestibular function	0.001	0.998	0.000
H81.4 Vertigo of central origin	0.001	0.998	0.000
H81.3 Other peripheral vertigo	0.001	0.998	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.001	0.998	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.001	0.998	0.000
H60.8 Other otitis externa	0.001	0.998	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.998	0.002
D22.5 Melanocytic naevi of trunk	0.000	0.998	0.001
G00.9 Bacterial meningitis, unspecified	0.001	0.998	0.000
H40.5 Glaucoma secondary to other eye disorders	0.001	0.998	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.001	0.998	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.001	0.998	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.001	0.998	0.000
H74.1 Adhesive middle ear disease	0.001	0.998	0.000
I72.3 Aneurysm of iliac artery	0.001	0.998	0.000
I78.9 Disease of capillaries, unspecified	0.001	0.998	0.000
I78.8 Other diseases of capillaries	0.001	0.998	0.000
F22 Persistent delusional disorders	0.000	0.998	0.001
G06 Intracranial and intraspinal abscess and granuloma	0.001	0.998	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.001	0.998	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.999	0.001
H66.3 Other chronic suppurative otitis media	0.001	0.999	0.000
L91.8 Other hypertrophic disorders of skin	0.000	0.999	0.001
D67 Hereditary factor IX deficiency	0.000	0.999	0.001
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.999	0.001
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.001	0.999	0.000
K13.29 Other disturbances of oral epithelium, including tongue	0.000	0.999	0.001
H60.5 Acute otitis externa, non-infective	0.001	0.999	0.000
H60.4 Cholesteatoma of external ear	0.001	0.999	0.000
H60.2 Malignant otitis externa	0.001	0.999	0.000
H60.0 Abscess of external ear	0.001	0.999	0.000
K73.9 Chronic hepatitis, unspecified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations