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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6590330
log Bayes Factor = <0.0001
Chromosome 11   position 128,311,059  (GRCh37) Explore rs6590330 on Ensembl!
Variant rs6590330 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K25.7 Chronic without haemorrhage or perforation
0.026 0.974 0.000
M51.2 Other specified intervertebral disk displacement
0.021 0.979 0.000
M51 Other intervertebral disk disorders
0.019 0.981 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.017 0.982 0.000
F20.9 Schizophrenia, unspecified
0.000 0.983 0.017
M54.9 Dorsalgia, unspecified
0.017 0.983 0.000
M54 Dorsalgia
0.017 0.983 0.000
M50-M54 Other dorsopathies
0.017 0.983 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.016 0.984 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.016 0.984 0.000
M51.3 Other specified intervertebral disk degeneration
0.015 0.985 0.000
M54.3 Sciatica
0.015 0.985 0.000
M54.4 Lumbago with sciatica
0.015 0.985 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.014 0.986 0.000
M50 Cervical disk disorders
0.014 0.986 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.014 0.986 0.000
M54.2 Cervicalgia
0.014 0.986 0.000
M51.4 Schmorl's nodes
0.013 0.987 0.000
F20 Schizophrenia
0.000 0.987 0.013
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.013 0.987 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.013 0.987 0.000
M54.36 Sciatica (Lumbar region)
0.013 0.987 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.013 0.987 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.013 0.987 0.000
F20.0 Paranoid schizophrenia
0.000 0.987 0.013
M51.9 Intervertebral disk disorder, unspecified
0.013 0.987 0.000
M50.3 Other cervical disk degeneration
0.012 0.987 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.012 0.988 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.012 0.988 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.012 0.988 0.000
M50.2 Other cervical disk displacement
0.012 0.988 0.000
M54.8 Other dorsalgia
0.012 0.988 0.000
M54.0 Panniculitis affecting regions of neck and back
0.012 0.988 0.000
M54.29 Cervicalgia-Site unspe
0.012 0.988 0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region
0.012 0.988 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.012 0.988 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.012 0.988 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.012 0.988 0.000
M54.39 Sciatica (Site unspecified)
0.012 0.988 0.000
M54.6 Pain in thoracic spine
0.012 0.988 0.000
M50.8 Other cervical disk disorders
0.012 0.988 0.000
M53 Other dorsopathies, not elsewhere classified
0.011 0.989 0.000
M54.35 Sciatica (Thoracolumbar region)
0.011 0.989 0.000
M54.34 Sciatica-Thoracic
0.011 0.989 0.000
M54.33 Sciatica-Cervicothoracic
0.011 0.989 0.000
M54.32 Sciatica-Cervical
0.011 0.989 0.000
M54.31 Sciatica-Occipit-atl-axl
0.011 0.989 0.000
M54.30 Sciatica (Multiple sites in spine)
0.011 0.989 0.000
W19.9 Unspecified place
0.000 0.989 0.011
M50.9 Cervical disk disorder, unspecified
0.011 0.989 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.011 0.989 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.011 0.989 0.000
M54.44 Lumbago with sciatica-Thoracic
0.011 0.989 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.011 0.989 0.000
M54.42 Lumbago with sciatica-Cervical
0.011 0.989 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.011 0.989 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.011 0.989 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.011 0.989 0.000
M51.8 Other specified intervertebral disk disorders
0.010 0.989 0.000
M54.37 Sciatica (Lumbosacral region)
0.010 0.989 0.000
M54.5 Low back pain
0.010 0.990 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.010 0.990 0.000
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified
0.010 0.990 0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region
0.010 0.990 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.010 0.990 0.000
M54.27 Cervicalgia-Lumbosacral
0.010 0.990 0.000
M54.26 Cervicalgia-Lumbar
0.010 0.990 0.000
M54.25 Cervicalgia-Thoracolumbar
0.010 0.990 0.000
M54.24 Cervicalgia-Thoracic
0.010 0.990 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.010 0.990 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.010 0.990 0.000
M54.20 Cervicalgia-Mult site
0.010 0.990 0.000
F20.8 Other schizophrenia
0.000 0.990 0.010
F20.6 Simple schizophrenia
0.000 0.990 0.010
F20.5 Residual schizophrenia
0.000 0.990 0.010
F20.4 Postschizophrenic depression
0.000 0.990 0.010
F20.3 Undifferentiated schizophrenia
0.000 0.990 0.010
F20.2 Catatonic schizophrenia
0.000 0.990 0.010
F20.1 Hebephrenic schizophrenia
0.000 0.990 0.010
K25 Gastric ulcer
0.010 0.990 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.010 0.990 0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)
0.009 0.991 0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)
0.009 0.991 0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)
0.009 0.991 0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)
0.009 0.991 0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)
0.009 0.991 0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)
0.009 0.991 0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)
0.009 0.991 0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)
0.009 0.991 0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)
0.009 0.991 0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)
0.009 0.991 0.000
M54.89 Other dorsalgia (Site unspecified)
0.009 0.991 0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)
0.009 0.991 0.000
M54.87 Other dorsalgia (Lumbosacral region)
0.009 0.991 0.000
M54.86 Other dorsalgia (Lumbar region)
0.009 0.991 0.000
M54.85 Other dorsalgia (Thoracolumbar region)
0.009 0.991 0.000
M54.84 Other dorsalgia (Thoracic region)
0.009 0.991 0.000
M54.83 Other dorsalgia (Cervicothoracic region)
0.009 0.991 0.000
M54.82 Other dorsalgia (Cervical region)
0.009 0.991 0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)
0.009 0.991 0.000
M54.80 Other dorsalgia (Multiple sites in spine)
0.009 0.991 0.000
M54.69 Pain in thoracic spine-Site unspe
0.008 0.991 0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ
0.008 0.991 0.000
M54.67 Pain in thoracic spine-Lumbosacral
0.008 0.991 0.000
M54.66 Pain in thoracic spine-Lumbar
0.008 0.991 0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)
0.008 0.991 0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.008 0.991 0.000
M54.62 Pain in thoracic spine-Cervical
0.008 0.991 0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl
0.008 0.991 0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)
0.008 0.991 0.000
M53.9 Dorsopathy, unspecified
0.008 0.992 0.000
M53.8 Other specified dorsopathies
0.008 0.992 0.000
M53.2 Spinal instabilities
0.008 0.992 0.000
M53.1 Cervicobrachial syndrome
0.008 0.992 0.000
M53.0 Cervicocranial syndrome
0.008 0.992 0.000
M54.22 Cervicalgia (Cervical region)
0.008 0.992 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.008 0.992 0.000
M54.55 Low back pain (Thoracolumbar region)
0.008 0.992 0.000
M54.54 Low back pain-Thoracic
0.008 0.992 0.000
M54.53 Low back pain-Cervicothoracic
0.008 0.992 0.000
M54.52 Low back pain-Cervical
0.008 0.992 0.000
M54.51 Low back pain-Occipit-atl-axl
0.008 0.992 0.000
K25.0 Acute with haemorrhage
0.008 0.992 0.000
M50.1 Cervical disk disorder with radiculopathy
0.008 0.992 0.000
M54.56 Low back pain (Lumbar region)
0.008 0.992 0.000
K25.4 Chronic or unspecified with haemorrhage
0.007 0.992 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.007 0.993 0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.007 0.993 0.000
K25.5 Chronic or unspecified with perforation
0.007 0.993 0.000
K25.2 Acute with both haemorrhage and perforation
0.007 0.993 0.000
K25.1 Acute with perforation
0.007 0.993 0.000
K25.3 Acute without haemorrhage or perforation
0.007 0.993 0.000
M54.50 Low back pain (Multiple sites in spine)
0.007 0.993 0.000
M53.09 Cervicocranial syndrome-Site unspe
0.006 0.994 0.000
M53.08 Cervicocranial syndrome-Sacral/sacrococ
0.006 0.994 0.000
M53.07 Cervicocranial syndrome-Lumbosacral
0.006 0.994 0.000
M53.06 Cervicocranial syndrome-Lumbar
0.006 0.994 0.000
M53.05 Cervicocranial syndrome-Thoracolumbar
0.006 0.994 0.000
M53.04 Cervicocranial syndrome-Thoracic
0.006 0.994 0.000
M53.03 Cervicocranial syndrome (Cervicothoracic region)
0.006 0.994 0.000
M53.02 Cervicocranial syndrome (Cervical region)
0.006 0.994 0.000
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)
0.006 0.994 0.000
M53.00 Cervicocranial syndrome (Multiple sites in spine)
0.006 0.994 0.000
M53.19 Cervicobrachial syndrome-Site unspe
0.006 0.994 0.000
M53.18 Cervicobrachial syndrome-Sacral/sacrococ
0.006 0.994 0.000
M53.17 Cervicobrachial syndrome-Lumbosacral
0.006 0.994 0.000
M53.16 Cervicobrachial syndrome-Lumbar
0.006 0.994 0.000
M53.15 Cervicobrachial syndrome-Thoracolumbar
0.006 0.994 0.000
M53.14 Cervicobrachial syndrome-Thoracic
0.006 0.994 0.000
M53.13 Cervicobrachial syndrome (Cervicothoracic region)
0.006 0.994 0.000
M53.12 Cervicobrachial syndrome (Cervical region)
0.006 0.994 0.000
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)
0.006 0.994 0.000
M53.10 Cervicobrachial syndrome (Multiple sites in spine)
0.006 0.994 0.000
M53.29 Spinal instabilities (Site unspecified)
0.006 0.994 0.000
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)
0.006 0.994 0.000
M53.27 Spinal instabilities (Lumbosacral region)
0.006 0.994 0.000
M53.26 Spinal instabilities (Lumbar region)
0.006 0.994 0.000
M53.25 Spinal instabilities (Thoracolumbar region)
0.006 0.994 0.000
M53.24 Spinal instabilities (Thoracic region)
0.006 0.994 0.000
M53.23 Spinal instabilities (Cervicothoracic region)
0.006 0.994 0.000
M53.22 Spinal instabilities (Cervical region)
0.006 0.994 0.000
M53.21 Spinal instabilities (Occipito-atlanto-axial region)
0.006 0.994 0.000
M53.20 Spinal instabilities (Multiple sites in spine)
0.006 0.994 0.000
M53.89 Other specified dorsopathies (Site unspecified)
0.006 0.994 0.000
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)
0.006 0.994 0.000
M53.87 Other specified dorsopathies (Lumbosacral region)
0.006 0.994 0.000
M53.86 Other specified dorsopathies (Lumbar region)
0.006 0.994 0.000
M53.85 Other specified dorsopathies (Thoracolumbar region)
0.006 0.994 0.000
M53.84 Other specified dorsopathies (Thoracic region)
0.006 0.994 0.000
M53.83 Other specified dorsopathies (Cervicothoracic region)
0.006 0.994 0.000
M53.82 Other specified dorsopathies (Cervical region)
0.006 0.994 0.000
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)
0.006 0.994 0.000
M53.80 Other specified dorsopathies (Multiple sites in spine)
0.006 0.994 0.000
M53.99 Dorsopathy, unspecified (Site unspecified)
0.006 0.994 0.000
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)
0.006 0.994 0.000
M53.97 Dorsopathy, unspecified (Lumbosacral region)
0.006 0.994 0.000
M53.96 Dorsopathy, unspecified (Lumbar region)
0.006 0.994 0.000
M53.95 Dorsopathy, unspecified (Thoracolumbar region)
0.006 0.994 0.000
M53.94 Dorsopathy, unspecified (Thoracic region)
0.006 0.994 0.000
M53.93 Dorsopathy, unspecified (Cervicothoracic region)
0.006 0.994 0.000
M53.92 Dorsopathy, unspecified (Cervical region)
0.006 0.994 0.000
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)
0.006 0.994 0.000
M53.90 Dorsopathy, unspecified (Multiple sites in spine)
0.006 0.994 0.000
N60.1 Diffuse cystic mastopathy
0.000 0.994 0.006
M54.57 Low back pain (Lumbosacral region)
0.006 0.994 0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns
0.006 0.994 0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac
0.005 0.994 0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar
0.005 0.994 0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol
0.005 0.994 0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic
0.005 0.994 0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot
0.005 0.994 0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical
0.005 0.994 0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-
0.005 0.994 0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit
0.005 0.994 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.005 0.995 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.000 0.995 0.005
M54.1 Radiculopathy
0.005 0.995 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.005 0.995 0.000
N60.3 Fibrosclerosis of breast
0.000 0.995 0.005
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.005 0.995 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.005 0.995 0.000
N60.2 Fibroadenosis of breast
0.000 0.995 0.005
N60 Benign mammary dysplasia
0.000 0.995 0.005
Y45.1 Salicylates
0.005 0.995 0.000
Y45.0 Opioids and related analgesics
0.005 0.995 0.000
M54.59 Low back pain (Site unspecified)
0.005 0.995 0.000
M50.0 Cervical disk disorder with myelopathy
0.004 0.995 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.005 0.995 0.000
M35.0 Sicca syndrome [Sjogren]
0.004 0.996 0.000
I51.7 Cardiomegaly
0.000 0.996 0.004
M84.1 Nonunion of fracture [pseudarthrosis]
0.004 0.996 0.000
N60.4 Mammary duct ectasia
0.000 0.996 0.004
Y45.8 Other analgesics and antipyretics
0.004 0.996 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.004 0.996 0.000
M79.79 Fibromyalgia (Site unspecified)
0.004 0.996 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.004 0.996 0.000
M54.14 Radiculopathy (Thoracic region)
0.004 0.996 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.004 0.996 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.004 0.996 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.004 0.996 0.000
W19 Unspecified fall
0.000 0.996 0.004
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.996 0.004
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.004 0.996 0.000
Y45.4 Antirheumatics
0.004 0.996 0.000
M84 Disorders of continuity of bone
0.004 0.996 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.004 0.996 0.000
Y45.5 4-Aminophenol derivatives
0.004 0.996 0.000
Y57.8 Other drugs and medicaments
0.004 0.996 0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s
0.003 0.996 0.001
I77.1 Stricture of artery
0.004 0.996 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.004 0.996 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.003 0.996 0.000
E03.9 Hypothyroidism, unspecified
0.004 0.996 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.000 0.997 0.003
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.003 0.997 0.000
M54.19 Radiculopathy (Site unspecified)
0.003 0.997 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.003 0.997 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.003 0.997 0.000
S82.30 Fracture of lower end of tibia (closed)
0.003 0.997 0.000
M80-M85 Disorders of bone density and structure
0.003 0.997 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.003 0.997 0.000
M84.0 Malunion of fracture
0.003 0.997 0.000
N60.9 Benign mammary dysplasia, unspecified
0.000 0.997 0.003
W19.2 School, other institution and public administrative area
0.000 0.997 0.003
Y57 Other and unspecified drugs and medicaments
0.003 0.997 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.003 0.997 0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.003 0.997 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.003 0.997 0.000
N60.8 Other benign mammary dysplasias
0.000 0.997 0.003
W19.3 Sports and athletics area
0.000 0.997 0.003
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.003 0.997 0.000
J06.9 Acute upper respiratory infection, unspecified
0.003 0.997 0.000
W19.8 Other specified place
0.000 0.997 0.003
W19.5 Trade and service area
0.000 0.997 0.003
W19.0 Home
0.000 0.997 0.003
W19.7 Farm
0.000 0.997 0.003
W19.6 Industrial and construction area
0.000 0.997 0.003
M80 Osteoporosis with pathological fracture
0.003 0.997 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.003 0.997 0.000
Y45.2 Propionic acid derivatives
0.003 0.997 0.000
M84.03 Malunion of fracture (Forearm)
0.003 0.997 0.000
M86.9 Osteomyelitis, unspecified
0.003 0.997 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.003 0.997 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.003 0.997 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.003 0.997 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.003 0.997 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.003 0.997 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.003 0.997 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.003 0.997 0.000
M84.9 Disorder of continuity of bone, unspecified
0.003 0.997 0.000
M84.8 Other disorders of continuity of bone
0.003 0.997 0.000
M84.4 Pathological fracture, not elsewhere classified
0.003 0.997 0.000
M84.3 Stress fracture, not elsewhere classified
0.003 0.997 0.000
M84.2 Delayed union of fracture
0.003 0.997 0.000
M82 Osteoporosis in diseases classified elsewhere
0.003 0.997 0.000
N28.1 Cyst of kidney, acquired
0.003 0.997 0.000
N60.0 Solitary cyst of breast
0.000 0.997 0.003
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.003 0.997 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.003 0.997 0.000
F25 Schizoaffective disorders
0.000 0.997 0.003
S72.10 Pertrochanteric fracture (closed)
0.003 0.997 0.000
H26.8 Other specified cataract
0.000 0.997 0.003
R94 Abnormal results of function studies
0.003 0.997 0.000
Y57.5 X-ray contrast media
0.003 0.997 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.003 0.997 0.000
F28 Other nonorganic psychotic disorders
0.000 0.997 0.003
F24 Induced delusional disorder
0.000 0.997 0.003
F21 Schizotypal disorder
0.000 0.997 0.003
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.003 0.997 0.000
T39.0 Salicylates
0.000 0.997 0.003
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.003 0.997 0.000
E55.9 Vitamin D deficiency, unspecified
0.003 0.997 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.003 0.997 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.003 0.997 0.000
M54.16 Radiculopathy (Lumbar region)
0.002 0.997 0.000
M82.1 Osteoporosis in endocrine disorders
0.003 0.997 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.003 0.997 0.000
W19.1 Residential institution
0.000 0.997 0.003
M54.12 Radiculopathy (Cervical region)
0.002 0.997 0.001
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)
0.003 0.997 0.000
M05 Seropositive rheumatoid arthritis
0.003 0.997 0.000
M83 Adult osteomalacia
0.003 0.997 0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.003 0.997 0.000
Y54.3 Benzothiadiazine derivatives
0.003 0.997 0.000
M81 Osteoporosis without pathological fracture
0.003 0.997 0.000
M84.09 Malunion of fracture (Site unspecified)
0.002 0.997 0.000
M84.08 Malunion of fracture (Other)
0.002 0.997 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.002 0.997 0.000
M84.06 Malunion of fracture (Lower leg)
0.002 0.997 0.000
M84.05 Malunion of fracture (Pelvic region and thigh)
0.002 0.997 0.000
M84.02 Malunion of fracture (Upper arm)
0.002 0.997 0.000
M84.01 Malunion of fracture (Shoulder region)
0.002 0.997 0.000
M84.00 Malunion of fracture (Multiple sites)
0.002 0.997 0.000
M85 Other disorders of bone density and structure
0.003 0.997 0.000
M86 Osteomyelitis
0.003 0.997 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.003 0.997 0.000
O42.9 Premature rupture of membranes, unspecified
0.003 0.997 0.000
R94.3 Abnormal results of cardiovascular function studies
0.003 0.997 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.003 0.997 0.000
M81.4 Drug-induced osteoporosis
0.003 0.997 0.000
Y57.7 Vitamins, not elsewhere classified
0.002 0.997 0.000
Y57.6 Other diagnostic agents
0.002 0.997 0.000
Y57.4 Pharmaceutical excipients
0.002 0.997 0.000
Y57.3 Alcohol deterrents
0.002 0.997 0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.002 0.997 0.000
Y57.1 Lipotropic drugs
0.002 0.997 0.000
Y57.0 Appetite depressants [anorectics]
0.002 0.997 0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.002 0.997 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.002 0.997 0.000
Y52 Agents primarily affecting the cardiovascular system
0.002 0.997 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.002 0.997 0.000
M84.04 Malunion of fracture (Hand)
0.002 0.997 0.000
M80.8 Other osteoporosis with pathological fracture
0.002 0.997 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.002 0.997 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.002 0.997 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.002 0.997 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.002 0.997 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.000 0.997 0.002
R92 Abnormal findings on diagnostic imaging of breast
0.002 0.997 0.000
W19.09 Unspecified fall; Home; During unspecified activity
0.000 0.998 0.002
W19.08 Unspecified fall; Home; While engaged in other specified activities
0.000 0.998 0.002
W19.59 Unspecified fall; Trade and service area; During unspecified activity
0.000 0.998 0.002
W19.81 Unspecified fall; Other specified places; While engaged in leisure activity
0.000 0.998 0.002
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.002 0.998 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.002 0.998 0.000
H95.1 Other disorders following mastoidectomy
0.002 0.998 0.000
J93.9 Pneumothorax, unspecified
0.002 0.998 0.000
F23 Acute and transient psychotic disorders
0.000 0.998 0.002
Y48 Anaesthetics and therapeutic gases
0.002 0.998 0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.002 0.998 0.000
M86.98 Osteomyelitis, unspecified (Other)
0.002 0.998 0.000
M86.96 Osteomyelitis, unspecified (Lower leg)
0.002 0.998 0.000
M86.94 Osteomyelitis, unspecified (Hand)
0.002 0.998 0.000
M86.93 Osteomyelitis, unspecified (Forearm)
0.002 0.998 0.000
M86.92 Osteomyelitis, unspecified (Upper arm)
0.002 0.998 0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.002 0.998 0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.002 0.998 0.000
Y54.8 Agents affecting uric acid metabolism
0.002 0.998 0.000
M84.29 Delayed union of fracture (Site unspecified)
0.002 0.998 0.000
M84.28 Delayed union of fracture (Other)
0.002 0.998 0.000
M84.27 Delayed union of fracture (Ankle and foot)
0.002 0.998 0.000
M84.26 Delayed union of fracture (Lower leg)
0.002 0.998 0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)
0.002 0.998 0.000
M84.24 Delayed union of fracture (Hand)
0.002 0.998 0.000
M84.23 Delayed union of fracture (Forearm)
0.002 0.998 0.000
M84.22 Delayed union of fracture (Upper arm)
0.002 0.998 0.000
M84.21 Delayed union of fracture (Shoulder region)
0.002 0.998 0.000
M84.20 Delayed union of fracture (Multiple sites)
0.002 0.998 0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)
0.002 0.998 0.000
M84.38 Stress fracture, not elsewhere classified (Other)
0.002 0.998 0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)
0.002 0.998 0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)
0.002 0.998 0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)
0.002 0.998 0.000
M84.34 Stress fracture, not elsewhere classified (Hand)
0.002 0.998 0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)
0.002 0.998 0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)
0.002 0.998 0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)
0.002 0.998 0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)
0.002 0.998 0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)
0.002 0.998 0.000
M84.48 Pathological fracture, not elsewhere classified (Other)
0.002 0.998 0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)
0.002 0.998 0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)
0.002 0.998 0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)
0.002 0.998 0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)
0.002 0.998 0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)
0.002 0.998 0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)
0.002 0.998 0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)
0.002 0.998 0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)
0.002 0.998 0.000
M84.89 Other disorders of continuity of bone (Site unspecified)
0.002 0.998 0.000
M84.88 Other disorders of continuity of bone (Other)
0.002 0.998 0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)
0.002 0.998 0.000
M84.86 Other disorders of continuity of bone (Lower leg)
0.002 0.998 0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)
0.002 0.998 0.000
M84.84 Other disorders of continuity of bone (Hand)
0.002 0.998 0.000
M84.83 Other disorders of continuity of bone (Forearm)
0.002 0.998 0.000
M84.82 Other disorders of continuity of bone (Upper arm)
0.002 0.998 0.000
M84.81 Other disorders of continuity of bone (Shoulder region)
0.002 0.998 0.000
M84.80 Other disorders of continuity of bone (Multiple sites)
0.002 0.998 0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)
0.002 0.998 0.000
M84.98 Disorder of continuity of bone, unspecified (Other)
0.002 0.998 0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)
0.002 0.998 0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)
0.002 0.998 0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)
0.002 0.998 0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)
0.002 0.998 0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)
0.002 0.998 0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)
0.002 0.998 0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)
0.002 0.998 0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)
0.002 0.998 0.000
Z89.4 Acquired absence of foot and ankle
0.002 0.998 0.000
Y44 Agents primarily affecting blood constituents
0.002 0.998 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.002 0.998 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.002 0.998 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.002 0.998 0.000
F29 Unspecified nonorganic psychosis
0.000 0.998 0.002
Y46 Antiepileptics and anti-Parkinsonism drugs
0.002 0.998 0.000
L53.8 Other specified erythematous conditions
0.002 0.998 0.000
R94.2 Abnormal results of pulmonary function studies
0.002 0.998 0.000
Y54.4 Loop [high-ceiling] diuretics
0.002 0.998 0.000
M86-M90 Other osteopathies
0.002 0.998 0.000
F25.9 Schizoaffective disorder, unspecified
0.000 0.998 0.002
M85.9 Disorder of bone density and structure, unspecified
0.002 0.998 0.000
Y57.9 Drug or medicament, unspecified
0.002 0.998 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.002 0.998 0.000
M62.88 Other specified disorders of muscle (Other)
0.002 0.998 0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)
0.002 0.998 0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)
0.002 0.998 0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)
0.002 0.998 0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)
0.002 0.998 0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)
0.002 0.998 0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)
0.002 0.998 0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)
0.002 0.998 0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)
0.002 0.998 0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)
0.002 0.998 0.000
F25.8 Other schizoaffective disorders
0.000 0.998 0.002
F25.2 Schizoaffective disorder, mixed type
0.000 0.998 0.002
F25.1 Schizoaffective disorder, depressive type
0.000 0.998 0.002
F25.0 Schizoaffective disorder, manic type
0.000 0.998 0.002
R94.7 Abnormal results of other endocrine function studies
0.002 0.998 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.002 0.998 0.000
R94.0 Abnormal results of function studies of central nervous system
0.002 0.998 0.000
H65.3 Chronic mucoid otitis media
0.002 0.998 0.000
I49.0 Ventricular fibrillation and flutter
0.000 0.998 0.002
M81.0 Postmenopausal osteoporosis
0.002 0.998 0.000
R94.6 Abnormal results of thyroid function studies
0.002 0.998 0.000
R94.4 Abnormal results of kidney function studies
0.002 0.998 0.000
F22 Persistent delusional disorders
0.000 0.998 0.002
Y43.1 Antineoplastic antimetabolites
0.002 0.998 0.000
Y55.6 Antiasthmatics, not elsewhere classified
0.002 0.998 0.000
Y59 Other and unspecified vaccines and biological substances
0.002 0.998 0.000
Y58 Bacterial vaccines
0.002 0.998 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.002 0.998 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.002 0.998 0.000
Y48.3 Local anaesthetics
0.002 0.998 0.000
Y54.9 Mineral salts, not elsewhere classified
0.002 0.998 0.000
Y54.7 Agents affecting calcification
0.002 0.998 0.000
Y54.6 Electrolytic, caloric and water-balance agents
0.002 0.998 0.000
Y54.2 Carbonic-anhydrase inhibitors
0.002 0.998 0.000
Y54.0 Mineralocorticoids
0.002 0.998 0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)
0.002 0.998 0.000
M82.18 Osteoporosis in endocrine disorders (Other)
0.002 0.998 0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)
0.002 0.998 0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)
0.002 0.998 0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)
0.002 0.998 0.000
M82.14 Osteoporosis in endocrine disorders (Hand)
0.002 0.998 0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)
0.002 0.998 0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)
0.002 0.998 0.000
F60.3 Emotionally unstable personality disorder
0.000 0.998 0.002
H93.1 Tinnitus
0.002 0.998 0.000
M05.8 Other seropositive rheumatoid arthritis
0.002 0.998 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.002 0.998 0.000
M05.2 Rheumatoid vasculitis
0.002 0.998 0.000
M05.1 Rheumatoid lung disease
0.002 0.998 0.000
M05.0 Felty's syndrome
0.002 0.998 0.000
M83.9 Adult osteomalacia, unspecified
0.002 0.998 0.000
M83.8 Other adult osteomalacia
0.002 0.998 0.000
M83.5 Other drug-induced osteomalacia in adults
0.002 0.998 0.000
M83.4 Aluminum bone disease
0.002 0.998 0.000
M83.3 Adult osteomalacia due to malnutrition
0.002 0.998 0.000
M83.2 Adult osteomalacia due to malabsorption
0.002 0.998 0.000
M83.1 Senile osteomalacia
0.002 0.998 0.000
M83.0 Puerperal osteomalacia
0.002 0.998 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.002 0.998 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.002 0.998 0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral
0.002 0.998 0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)
0.002 0.998 0.000
L53.9 Erythematous condition, unspecified
0.002 0.998 0.000
M62.8 Other specified disorders of muscle
0.002 0.998 0.000
W19.4 Street and highway
0.000 0.998 0.002
M81.8 Other osteoporosis
0.002 0.998 0.000
M81.6 Localised osteoporosis [Lequesne]
0.002 0.998 0.000
M81.5 Idiopathic osteoporosis
0.002 0.998 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.002 0.998 0.000
M81.1 Postoophorectomy osteoporosis
0.002 0.998 0.000
M85.6 Other cyst of bone
0.002 0.998 0.000
M86.8 Other osteomyelitis
0.002 0.998 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.002 0.998 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.002 0.998 0.000
M86.3 Chronic multifocal osteomyelitis
0.002 0.998 0.000
M86.2 Subacute osteomyelitis
0.002 0.998 0.000
M86.1 Other acute osteomyelitis
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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