TreeWAS – Variant ID: rs6662617

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C15.9 Oesophagus, unspecified	0.021	0.979	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.980	0.020
C15 Malignant neoplasm of oesophagus	0.016	0.984	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.986	0.014
C15.5 Lower third of oesophagus	0.013	0.987	0.000
C15.4 Middle third of oesophagus	0.013	0.987	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.987	0.013
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.988	0.012
C15.3 Upper third of oesophagus	0.012	0.988	0.000
C15.0 Cervical part of oesophagus	0.012	0.988	0.000
C15.8 Overlapping lesion of oesophagus	0.011	0.989	0.000
C15.2 Abdominal part of oesophagus	0.011	0.989	0.000
C15.1 Thoracic part of oesophagus	0.011	0.989	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.990	0.010
D89.1 Cryoglobulinaemia	0.000	0.990	0.009
D89.3 Immune reconstitution syndrome	0.000	0.990	0.009
Z85.5 Personal history of malignant neoplasm of urinary tract	0.000	0.991	0.009
D68 Other coagulation defects	0.000	0.991	0.009
D68.8 Other specified coagulation defects	0.000	0.991	0.009
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.991	0.009
D80-D89 Certain disorders involving the immune mechanism	0.000	0.991	0.009
D68.5 Primary Thrombophilia	0.000	0.992	0.008
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.992	0.008
D86 Sarcoidosis	0.000	0.993	0.007
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.993	0.007
D86.0 Sarcoidosis of lung	0.000	0.993	0.007
D86.3 Sarcoidosis of skin	0.000	0.993	0.007
E55.9 Vitamin D deficiency, unspecified	0.007	0.993	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.993	0.007
D68.6 Other Thrombophilia	0.000	0.993	0.006
D80 Immunodeficiency with predominantly antibody defects	0.000	0.993	0.006
D68.4 Acquired coagulation factor deficiency	0.000	0.993	0.006
D81 Combined immunodeficiencies	0.000	0.994	0.006
R45.1 Restlessness and agitation	0.006	0.994	0.000
D84 Other immunodeficiencies	0.000	0.994	0.006
D68.1 Hereditary factor XI deficiency	0.000	0.994	0.006
D83 Common variable immunodeficiency	0.000	0.994	0.006
D68.0 Von Willebrand's disease	0.000	0.994	0.006
E22.0 Acromegaly and pituitary gigantism	0.006	0.994	0.000
M10.99 Gout, unspecified (Site unspecified)	0.000	0.994	0.006
D82.1 Di George's syndrome	0.000	0.995	0.005
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.995	0.005
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.995	0.005
D86.9 Sarcoidosis, unspecified	0.000	0.995	0.005
C67.4 Posterior wall of bladder	0.000	0.995	0.005
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.995	0.005
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.995	0.005
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.995	0.005
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.995	0.005
D82.2 Immunodeficiency with short-limbed stature	0.000	0.995	0.005
D82.0 Wiskott-Aldrich syndrome	0.000	0.995	0.005
D86.8 Sarcoidosis of other and combined sites	0.000	0.995	0.005
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.995	0.005
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.995	0.005
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.995	0.005
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.995	0.005
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.995	0.005
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.995	0.005
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.995	0.005
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.995	0.005
D84.9 Immunodeficiency, unspecified	0.000	0.995	0.005
D81.9 Combined immunodeficiency, unspecified	0.000	0.995	0.005
D81.8 Other combined immunodeficiencies	0.000	0.995	0.005
D81.7 Major histocompatibility complex class II deficiency	0.000	0.995	0.005
D81.6 Major histocompatibility complex class I deficiency	0.000	0.995	0.005
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.995	0.005
D81.4 Nezelof's syndrome	0.000	0.995	0.005
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.995	0.005
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.995	0.005
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.995	0.005
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.995	0.005
R45 Symptoms and signs involving emotional state	0.005	0.995	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.000	0.995	0.005
H90.3 Sensorineural hearing loss, bilateral	0.005	0.995	0.000
D84.8 Other specified immunodeficiencies	0.000	0.995	0.004
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.995	0.004
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.995	0.004
L97 Ulcer of lower limb, not elsewhere classified	0.000	0.995	0.005
D83.8 Other common variable immunodeficiencies	0.000	0.995	0.004
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.995	0.004
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.995	0.004
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.995	0.004
R45.7 State of emotional shock and stress, unspecified	0.005	0.995	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.995	0.004
M10.94 Gout, unspecified (Hand)	0.000	0.996	0.004
D68.9 Coagulation defect, unspecified	0.000	0.996	0.004
R45.4 Irritability and anger	0.004	0.996	0.000
M10.9 Gout, unspecified	0.000	0.996	0.004
C67.2 Lateral wall of bladder	0.000	0.996	0.004
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.996	0.004
D84.1 Defects in the complement system	0.000	0.996	0.004
D83.9 Common variable immunodeficiency, unspecified	0.000	0.996	0.004
D86.1 Sarcoidosis of lymph nodes	0.000	0.996	0.004
E55 Vitamin D deficiency	0.004	0.996	0.000
R45.0 Nervousness	0.004	0.996	0.000
R45.6 Physical violence	0.004	0.996	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.996	0.004
D67 Hereditary factor IX deficiency	0.000	0.996	0.004
N83.3 Acquired atrophy of ovary and Fallopian tube	0.000	0.996	0.004
R45.2 Unhappiness	0.004	0.996	0.000
R45.3 Demoralisation and apathy	0.004	0.996	0.000
D66 Hereditary factor VIII deficiency	0.000	0.996	0.004
M10.90 Gout, unspecified (Multiple sites)	0.000	0.996	0.004
C67 Malignant neoplasm of bladder	0.000	0.996	0.004
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.997	0.003
M10.98 Gout, unspecified (Other)	0.000	0.997	0.003
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
M10.91 Gout, unspecified (Shoulder region)	0.000	0.997	0.003
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.001	0.997	0.003
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.997	0.003
R45.8 Other symptoms and signs involving emotional state	0.003	0.997	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.997	0.003
E55.0 Rickets, active	0.003	0.997	0.000
F40.0 Agoraphobia	0.003	0.997	0.000
R45.5 Hostility	0.003	0.997	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
M10.93 Gout, unspecified (Forearm)	0.000	0.997	0.003
C67.8 Overlapping lesion of bladder	0.000	0.997	0.003
Z00.0 General medical examination	0.003	0.997	0.000
C67.3 Anterior wall of bladder	0.000	0.997	0.003
C67.6 Ureteric orifice	0.000	0.997	0.003
S52.60 Fracture of lower end of both ulna and radius (closed)	0.000	0.997	0.003
I74.5 Embolism and thrombosis of iliac artery	0.000	0.997	0.003
C67.7 Urachus	0.000	0.997	0.003
F43.2 Adjustment disorders	0.003	0.997	0.000
M10.92 Gout, unspecified (Upper arm)	0.000	0.997	0.003
H11.1 Conjunctival degenerations and deposits	0.003	0.997	0.000
C67.1 Dome of bladder	0.000	0.997	0.003
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.997	0.003
R87.7 Abnormal histological findings	0.003	0.997	0.000
R87.9 Unspecified abnormal finding	0.003	0.997	0.000
G56.2 Lesion of ulnar nerve	0.003	0.997	0.000
I74 Arterial embolism and thrombosis	0.000	0.997	0.003
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.997	0.003
S51.0 Open wound of elbow	0.003	0.997	0.000
R85.5 Abnormal microbiological findings	0.003	0.997	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.998	0.002
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.002	0.998	0.000
C67.0 Trigone of bladder	0.000	0.998	0.002
F23.9 Acute and transient psychotic disorder, unspecified	0.002	0.998	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.000	0.998	0.002
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.002	0.998	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.998	0.002
Q85.0 Neurofibromatosis (nonmalignant)	0.000	0.998	0.002
R87 Abnormal findings in specimens from female genital organs	0.002	0.998	0.000
H02.1 Ectropion of eyelid	0.002	0.998	0.000
I71.0 Dissection of aorta [any part]	0.000	0.998	0.002
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.998	0.002
M10.96 Gout, unspecified (Lower leg)	0.000	0.998	0.002
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.998	0.002
H83.0 Labyrinthitis	0.002	0.998	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.998	0.002
I71 Aortic aneurysm and dissection	0.000	0.998	0.002
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.002	0.998	0.000
Q07.0 Arnold-Chiari syndrome	0.000	0.998	0.002
S51.9 Open wound of forearm, part unspecified	0.002	0.998	0.000
T59.8 Other specified gases, fumes and vapours	0.002	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.000	0.998	0.002
R87.0 Abnormal level of enzymes	0.002	0.998	0.000
Z54.4 Convalescence following treatment of fracture	0.002	0.998	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.998	0.002
D55-D59 Haemolytic anaemias	0.000	0.998	0.002
R85.7 Abnormal histological findings	0.002	0.998	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.998	0.002
V11.4 Driver injured in traffic accident	0.002	0.998	0.000
C67.5 Bladder neck	0.000	0.998	0.002
D72.1 Eosinophilia	0.000	0.998	0.002
D72 Other disorders of white blood cells	0.000	0.998	0.002
E50-E64 Other nutritional deficiencies	0.002	0.998	0.000
R86.8 Other abnormal findings	0.002	0.998	0.000
R87.8 Other abnormal findings	0.002	0.998	0.000
R87.5 Abnormal microbiological findings	0.002	0.998	0.000
R87.4 Abnormal immunological findings	0.002	0.998	0.000
R87.3 Abnormal level of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
R87.2 Abnormal level of other drugs, medicaments and biological substances	0.002	0.998	0.000
R87.1 Abnormal level of hormones	0.002	0.998	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.002	0.998	0.000
D72.8 Other specified disorders of white blood cells	0.000	0.998	0.002
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.002	0.998	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.998	0.002
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I98.0 Cardiovascular syphilis	0.000	0.998	0.002
S20.8 Superficial injuries of other and unspecified parts of thorax	0.002	0.998	0.000
C65 Malignant neoplasm of renal pelvis	0.000	0.998	0.002
R85.9 Unspecified abnormal finding	0.002	0.998	0.000
D46 Myelodysplastic syndromes	0.000	0.998	0.002
R89 Abnormal findings in specimens from other organs, systems and tissues	0.002	0.998	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.998	0.002
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.998	0.002
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.998	0.002
I74.8 Embolism and thrombosis of other arteries	0.000	0.998	0.002
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.002	0.998	0.000
R85.6 Abnormal cytological findings	0.002	0.998	0.000
R85.4 Abnormal immunological findings	0.002	0.998	0.000
R85.3 Abnormal level of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
R85.2 Abnormal level of other drugs, medicaments and biological substances	0.002	0.998	0.000
R85.1 Abnormal level of hormones	0.002	0.998	0.000
R85.0 Abnormal level of enzymes	0.002	0.998	0.000
J32.0 Chronic maxillary sinusitis	0.002	0.998	0.000
D56 Thalassaemia	0.000	0.998	0.002
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.002	0.998	0.000
R89.7 Abnormal histological findings	0.002	0.998	0.000
E51 Thiamine deficiency	0.002	0.998	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.002	0.998	0.000
D46.4 Refractory anaemia, unspecified	0.000	0.998	0.002
D62 Acute posthaemorrhagic anaemia	0.000	0.998	0.002
I12.9 Hypertensive renal disease without renal failure	0.002	0.998	0.000
D55 Anaemia due to enzyme disorders	0.000	0.998	0.002
E56 Other vitamin deficiencies	0.002	0.998	0.000
N60.0 Solitary cyst of breast	0.000	0.998	0.002
Z54.0 Convalescence following surgery	0.002	0.998	0.000
F23 Acute and transient psychotic disorders	0.002	0.998	0.000
R86 Abnormal findings in specimens from male genital organs	0.002	0.998	0.000
R84 Abnormal findings in specimens from respiratory organs and thorax	0.002	0.998	0.000
M79.10 Myalgia (Multiple sites)	0.000	0.998	0.002
E51.2 Wernicke's encephalopathy	0.002	0.998	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.998	0.002
H47.3 Other disorders of optic disk	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.002
E53.9 Vitamin B deficiency, unspecified	0.002	0.998	0.000
D60-D64 Aplastic and other anaemias	0.000	0.998	0.002
C67.9 Bladder, unspecified	0.000	0.998	0.002
D56.3 Thalassaemia trait	0.000	0.998	0.002
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.998	0.002
D58 Other hereditary haemolytic anaemias	0.000	0.998	0.002
T59 Toxic effect of other gases, fumes and vapours	0.002	0.998	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.998	0.002
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
D72.9 Disorder of white blood cells, unspecified	0.000	0.998	0.002
D72.0 Genetic anomalies of leukocytes	0.000	0.998	0.002
N28.8 Other specified disorders of kidney and ureter	0.000	0.998	0.002
D57 Sickle-cell disorders	0.000	0.998	0.002
E64 Sequelae of malnutrition and other nutritional deficiencies	0.002	0.998	0.000
E63 Other nutritional deficiencies	0.002	0.998	0.000
E50 Vitamin A deficiency	0.002	0.998	0.000
E60 Dietary zinc deficiency	0.002	0.998	0.000
E59 Dietary selenium deficiency	0.002	0.998	0.000
E54 Ascorbic acid deficiency	0.002	0.998	0.000
E52 Niacin deficiency [pellagra]	0.002	0.998	0.000
R89.5 Abnormal microbiological findings	0.002	0.998	0.000
S20.2 Contusion of thorax	0.002	0.998	0.000
S51 Open wound of forearm	0.002	0.998	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.000	0.998	0.002
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.002	0.998	0.000
S19.9 Unspecified injury of neck	0.002	0.998	0.000
E61 Deficiency of other nutrient elements	0.002	0.998	0.000
C64-C68 Malignant neoplasms of urinary tract	0.000	0.998	0.002
R89.9 Unspecified abnormal finding	0.001	0.998	0.000
R89.8 Other abnormal findings	0.001	0.998	0.000
R89.6 Abnormal cytological findings	0.001	0.998	0.000
R89.4 Abnormal immunological findings	0.001	0.998	0.000
R89.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.998	0.000
R89.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.998	0.000
R89.1 Abnormal level of hormones	0.001	0.998	0.000
R89.0 Abnormal level of enzymes	0.001	0.998	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.002	0.998	0.000
D46.7 Other myelodysplastic syndromes	0.000	0.998	0.002
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.000	0.998	0.002
D46.3 Refractory anaemia with excess of blasts with transformation	0.000	0.998	0.002
D46.0 Refractory anaemia without sideroblasts, so stated	0.000	0.998	0.002
R85.8 Other abnormal findings	0.001	0.998	0.000
C68.0 Urethra	0.000	0.998	0.002
D46.1 Refractory anaemia with sideroblasts	0.000	0.998	0.002
D56.9 Thalassaemia, unspecified	0.000	0.998	0.001
D56.8 Other thalassaemias	0.000	0.998	0.001
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.000	0.998	0.001
D56.2 Delta-beta thalassaemia	0.000	0.998	0.001
D56.0 Alpha thalassaemia	0.000	0.998	0.001
E56.1 Deficiency of vitamin K	0.001	0.998	0.000
K09.2 Other cysts of jaw	0.002	0.998	0.000
E58 Dietary calcium deficiency	0.002	0.998	0.000
R84.7 Abnormal histological findings	0.001	0.998	0.000
R86.5 Abnormal microbiological findings	0.001	0.998	0.000
V18.1 Passenger injured in nontraffic accident	0.002	0.998	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.000	0.998	0.002
D69 Purpura and other haemorrhagic conditions	0.000	0.998	0.002
D46.2 Refractory anaemia with excess of blasts	0.000	0.998	0.001
D56.1 Beta thalassaemia	0.000	0.998	0.001
D58.2 Other haemoglobinopathies	0.000	0.998	0.001
E51.9 Thiamine deficiency, unspecified	0.001	0.998	0.000
E51.8 Other manifestations of thiamine deficiency	0.001	0.998	0.000
E51.1 Beriberi	0.001	0.998	0.000
T59.9 Gases, fumes and vapours, unspecified	0.001	0.998	0.000
V11 Pedal cyclist injured in collision with other pedal cycle	0.002	0.998	0.000
D10.1 Tongue	0.002	0.998	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.000	0.998	0.002
M19.00 Primary arthrosis of other joints (Multiple sites)	0.002	0.998	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.998	0.002
R84.5 Abnormal microbiological findings	0.001	0.998	0.000
R86.0 Abnormal level of enzymes	0.001	0.998	0.000
S20.1 Other and unspecified superficial injuries of breast	0.002	0.998	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.998	0.001
D55.8 Other anaemias due to enzyme disorders	0.000	0.998	0.001
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.998	0.001
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.998	0.001
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.998	0.001
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.998	0.001
E56.9 Vitamin deficiency, unspecified	0.001	0.998	0.000
E56.8 Deficiency of other vitamins	0.001	0.998	0.000
E56.0 Deficiency of vitamin E	0.001	0.998	0.000
R86.4 Abnormal immunological findings	0.001	0.998	0.000
R86.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.998	0.000
R86.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.998	0.000
R86.1 Abnormal level of hormones	0.001	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.998	0.002
F23.8 Other acute and transient psychotic disorders	0.001	0.998	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.001	0.998	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.001	0.998	0.000
I44.7 Left bundle-branch block, unspecified	0.002	0.998	0.000
K14.0 Glossitis	0.002	0.998	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.002	0.998	0.000
R84.9 Unspecified abnormal finding	0.001	0.998	0.000
R84.8 Other abnormal findings	0.001	0.998	0.000
R84.4 Abnormal immunological findings	0.001	0.998	0.000
R84.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.998	0.000
R84.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.998	0.000
R84.1 Abnormal level of hormones	0.001	0.998	0.000
R84.0 Abnormal level of enzymes	0.001	0.998	0.000
E22 Hyperfunction of pituitary gland	0.001	0.998	0.000
M10 Gout	0.000	0.998	0.002
E61.2 Magnesium deficiency	0.001	0.998	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.998	0.001
F40 Phobic anxiety disorders	0.002	0.998	0.000
R83 Abnormal findings in cerebrospinal fluid	0.001	0.998	0.000
D57.8 Other sickle-cell disorders	0.000	0.998	0.001
D57.3 Sickle-cell trait	0.000	0.998	0.001
D57.2 Double heterozygous sickling disorders	0.000	0.998	0.001
D57.0 Sickle-cell anaemia with crisis	0.000	0.998	0.001
D58.8 Other specified hereditary haemolytic anaemias	0.000	0.998	0.001
D58.1 Hereditary elliptocytosis	0.000	0.998	0.001
E50.9 Vitamin A deficiency, unspecified	0.001	0.998	0.000
E50.8 Other manifestations of vitamin A deficiency	0.001	0.998	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.001	0.998	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.001	0.998	0.000
E50.5 Vitamin A deficiency with night blindness	0.001	0.998	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.001	0.998	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.001	0.998	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.001	0.998	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.001	0.998	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.001	0.998	0.000
E63.9 Nutritional deficiency, unspecified	0.001	0.998	0.000
E63.8 Other specified nutritional deficiencies	0.001	0.998	0.000
E63.1 Imbalance of constituents of food intake	0.001	0.998	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.001	0.998	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.001	0.998	0.000
E64.8 Sequelae of other nutritional deficiencies	0.001	0.998	0.000
E64.3 Sequelae of rickets	0.001	0.998	0.000
E64.2 Sequelae of vitamin C deficiency	0.001	0.998	0.000
E64.1 Sequelae of vitamin A deficiency	0.001	0.998	0.000
E64.0 Sequelae of protein-energy malnutrition	0.001	0.998	0.000
J01.9 Acute sinusitis, unspecified	0.001	0.998	0.000
T59.7 Carbon dioxide	0.001	0.998	0.000
T59.6 Hydrogen sulphide	0.001	0.998	0.000
T59.5 Fluorine gas and hydrogen fluoride	0.001	0.998	0.000
T59.4 Chlorine gas	0.001	0.998	0.000
T59.3 Lachrymogenic gas	0.001	0.998	0.000
T59.2 Formaldehyde	0.001	0.998	0.000
T59.1 Sulphur dioxide	0.001	0.998	0.000
T59.0 Nitrogen oxides	0.001	0.998	0.000
D74 Methaemoglobinaemia	0.000	0.998	0.001
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.998	0.001
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.998	0.001
V18 Pedal cyclist injured in noncollision transport accident	0.001	0.998	0.000
D48.0 Bone and articular cartilage	0.000	0.999	0.001
D73.4 Cyst of spleen	0.000	0.999	0.001
E61.9 Deficiency of nutrient element, unspecified	0.001	0.999	0.000
E61.8 Deficiency of other specified nutrient elements	0.001	0.999	0.000
E61.7 Deficiency of multiple nutrient elements	0.001	0.999	0.000
E61.6 Vanadium deficiency	0.001	0.999	0.000
E61.5 Molybdenum deficiency	0.001	0.999	0.000
E61.4 Chromium deficiency	0.001	0.999	0.000
E61.3 Manganese deficiency	0.001	0.999	0.000
E61.0 Copper deficiency	0.001	0.999	0.000
F40.1 Social phobias	0.001	0.999	0.000
I60.8 Other subarachnoid haemorrhage	0.001	0.999	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.999	0.001
I89.0 Lymphoedema, not elsewhere classified	0.000	0.999	0.001
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.999	0.000
Z57.2 Occupational exposure to dust	0.000	0.999	0.001
E53 Deficiency of other B group vitamins	0.001	0.999	0.000
S20 Superficial injury of thorax	0.001	0.999	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.999	0.001
O34.1 Maternal care for tumour of corpus uteri	0.001	0.999	0.000
R84.6 Abnormal cytological findings	0.001	0.999	0.000
S51.7 Multiple open wounds of forearm	0.001	0.999	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.999	0.001
Z54 Convalescence	0.001	0.999	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.000	0.999	0.001
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.001	0.999	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.000	0.999	0.001
T58 Toxic effect of carbon monoxide	0.001	0.999	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.999	0.001
C68.8 Overlapping lesion of urinary organs	0.000	0.999	0.001
C68.1 Paraurethral glands	0.000	0.999	0.001
D69.8 Other specified haemorrhagic conditions	0.000	0.999	0.001
H47.1 Papilloedema, unspecified	0.001	0.999	0.000
I33.0 Acute and subacute infective endocarditis	0.001	0.999	0.000
V11.9 Unspecified pedal cyclist injured in traffic accident	0.001	0.999	0.000
V11.5 Passenger injured in traffic accident	0.001	0.999	0.000
V11.3 Person injured while boarding or alighting	0.001	0.999	0.000
V11.2 Unspecified pedal cyclist injured in nontraffic accident	0.001	0.999	0.000
V11.1 Passenger injured in nontraffic accident	0.001	0.999	0.000
V11.0 Driver injured in nontraffic accident	0.001	0.999	0.000
W13.9 Unspecified place	0.001	0.999	0.000
D57.1 Sickle-cell anaemia without crisis	0.000	0.999	0.001
M19.04 Primary arthrosis of other joints (Hand)	0.001	0.999	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.999	0.001
C68.9 Urinary organ, unspecified	0.000	0.999	0.001
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.999	0.001
M10.4 Other secondary gout	0.000	0.999	0.001
M10.3 Gout due to impairment of renal function	0.000	0.999	0.001
M10.2 Drug-induced gout	0.000	0.999	0.001
M10.1 Lead-induced gout	0.000	0.999	0.001
R86.9 Unspecified abnormal finding	0.001	0.999	0.000
R86.6 Abnormal cytological findings	0.001	0.999	0.000
H83 Other diseases of inner ear	0.001	0.999	0.000
M25.34 Other instability of joint (Hand)	0.001	0.999	0.000
D58.0 Hereditary spherocytosis	0.000	0.999	0.001
D60.9 Acquired pure red cell aplasia, unspecified	0.000	0.999	0.001
D60.8 Other acquired pure red cell aplasias	0.000	0.999	0.001
D60.1 Transient acquired pure red cell aplasia	0.000	0.999	0.001
D60.0 Chronic acquired pure red cell aplasia	0.000	0.999	0.001
D69.5 Secondary thrombocytopenia	0.000	0.999	0.001
E22.9 Hyperfunction of pituitary gland, unspecified	0.001	0.999	0.000
E22.8 Other hyperfunction of pituitary gland	0.001	0.999	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.001	0.999	0.000
J01.0 Acute maxillary sinusitis	0.001	0.999	0.000
M19.0 Primary arthrosis of other joints	0.001	0.999	0.000
R83.9 Unspecified abnormal finding	0.001	0.999	0.000
R83.7 Abnormal histological findings	0.001	0.999	0.000
R83.6 Abnormal cytological findings	0.001	0.999	0.000
R83.5 Abnormal microbiological findings	0.001	0.999	0.000
R83.4 Abnormal immunological findings	0.001	0.999	0.000
R83.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
R83.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.999	0.000
R83.1 Abnormal level of hormones	0.001	0.999	0.000
R83.0 Abnormal level of enzymes	0.001	0.999	0.000
T56.8 Other metals	0.001	0.999	0.000
D69.9 Haemorrhagic condition, unspecified	0.000	0.999	0.001
D69.2 Other nonthrombocytopenic purpura	0.000	0.999	0.001
D74.9 Methaemoglobinaemia, unspecified	0.000	0.999	0.001
D74.8 Other methaemoglobinaemias	0.000	0.999	0.001
D74.0 Congenital methaemoglobinaemia	0.000	0.999	0.001
E22.1 Hyperprolactinaemia	0.001	0.999	0.000
F30.0 Hypomania	0.000	0.999	0.001
H83.9 Disease of inner ear, unspecified	0.001	0.999	0.000
Q21.0 Ventricular septal defect	0.000	0.999	0.001
R86.7 Abnormal histological findings	0.001	0.999	0.000
V10.4 Driver injured in traffic accident	0.001	0.999	0.000
V18.9 Unspecified pedal cyclist injured in traffic accident	0.001	0.999	0.000
V18.4 Driver injured in traffic accident	0.001	0.999	0.000
W02.9 Unspecified place	0.001	0.999	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.000	0.999	0.001
Z54.8 Convalescence following other treatment	0.001	0.999	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.001	0.999	0.000
D61.1 Drug-induced aplastic anaemia	0.000	0.999	0.001
D69.6 Thrombocytopenia, unspecified	0.000	0.999	0.001
D69.4 Other primary thrombocytopenia	0.000	0.999	0.001
E53.1 Pyridoxine deficiency	0.001	0.999	0.000
E53.0 Riboflavin deficiency	0.001	0.999	0.000
F40.8 Other phobic anxiety disorders	0.001	0.999	0.000
H93.1 Tinnitus	0.001	0.999	0.000
S20.7 Multiple superficial injuries of thorax	0.001	0.999	0.000
T54.9 Corrosive substance, unspecified	0.001	0.999	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.001	0.999	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.999	0.001
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.999	0.001
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.999	0.001
J01.8 Other acute sinusitis	0.001	0.999	0.000
S20.4 Other superficial injuries of back wall of thorax	0.001	0.999	0.000
V18.5 Passenger injured in traffic accident	0.001	0.999	0.000
Z54.7 Convalescence following combined treatment	0.001	0.999	0.000
Z54.3 Convalescence following psychotherapy	0.001	0.999	0.000
Z54.2 Convalescence following chemotherapy	0.001	0.999	0.000
Z54.1 Convalescence following radiotherapy	0.001	0.999	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.001	0.999	0.000
D69.1 Qualitative platelet defects	0.000	0.999	0.001
E61.1 Iron deficiency	0.001	0.999	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.000	0.999	0.001
H83.8 Other specified diseases of inner ear	0.001	0.999	0.000
J01.4 Acute pansinusitis	0.001	0.999	0.000
D73 Diseases of spleen	0.000	0.999	0.001
M43.02 Spondylolysis (Cervical region)	0.001	0.999	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.999	0.001
M86.98 Osteomyelitis, unspecified (Other)	0.000	0.999	0.001
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
F40.9 Phobic anxiety disorder, unspecified	0.001	0.999	0.000
H69.9 Eustachian tube disorder, unspecified	0.001	0.999	0.000
M86.9 Osteomyelitis, unspecified	0.000	0.999	0.001
J01 Acute sinusitis	0.001	0.999	0.000
V10 Pedal cyclist injured in collision with pedestrian or animal	0.001	0.999	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.999	0.001
M79.11 Myalgia (Shoulder region)	0.000	0.999	0.001
H83.1 Labyrinthine fistula	0.001	0.999	0.000
J01.2 Acute ethmoidal sinusitis	0.001	0.999	0.000
Z48.0 Attention to surgical dressings and sutures	0.000	0.999	0.001
T56 Toxic effect of metals	0.001	0.999	0.000
M10.19 Lead-induced gout (Site unspecified)	0.000	0.999	0.001
M10.18 Lead-induced gout (Other)	0.000	0.999	0.001
M10.17 Lead-induced gout (Ankle and foot)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations