TreeWAS – Variant ID: rs6669543

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N84.0 Polyp of corpus uteri	0.000	0.984	0.016
R22.3 Localised swelling, mass and lump, upper limb	0.000	0.989	0.011
C77.1 Intrathoracic lymph nodes	0.000	0.990	0.010
E23.2 Diabetes insipidus	0.008	0.992	0.000
E23 Hypofunction and other disorders of pituitary gland	0.007	0.993	0.000
E27.2 Addisonian crisis	0.007	0.993	0.000
E23.0 Hypopituitarism	0.007	0.993	0.000
Z87.8 Personal history of other specified conditions	0.007	0.993	0.000
E27 Other disorders of adrenal gland	0.007	0.993	0.000
E27.1 Primary adrenocortical insufficiency	0.006	0.994	0.000
E20-E35 Disorders of other endocrine glands	0.006	0.994	0.000
E23.6 Other disorders of pituitary gland	0.006	0.994	0.000
E29 Testicular dysfunction	0.006	0.994	0.000
J98.1 Pulmonary collapse	0.000	0.994	0.006
E29.1 Testicular hypofunction	0.006	0.994	0.000
K81.9 Cholecystitis, unspecified	0.006	0.994	0.000
E23.1 Drug-induced hypopituitarism	0.005	0.994	0.000
M84.04 Malunion of fracture (Hand)	0.006	0.994	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.005	0.994	0.000
M84.0 Malunion of fracture	0.006	0.994	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.005	0.995	0.000
E20 Hypoparathyroidism	0.005	0.995	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.000	0.995	0.005
M84.03 Malunion of fracture (Forearm)	0.005	0.995	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.005	0.995	0.000
E32 Diseases of thymus	0.005	0.995	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.005	0.995	0.000
J98 Other respiratory disorders	0.000	0.995	0.005
E27.5 Adrenomedullary hyperfunction	0.005	0.995	0.000
E27.0 Other adrenocortical overactivity	0.005	0.995	0.000
E31 Polyglandular dysfunction	0.005	0.995	0.000
J98.4 Other disorders of lung	0.000	0.995	0.005
M84.06 Malunion of fracture (Lower leg)	0.005	0.995	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.005	0.995	0.000
E30 Disorders of puberty, not elsewhere classified	0.005	0.995	0.000
E26 Hyperaldosteronism	0.005	0.995	0.000
E27.9 Disorder of adrenal gland, unspecified	0.005	0.995	0.000
E25 Adrenogenital disorders	0.005	0.995	0.000
J98.9 Respiratory disorder, unspecified	0.000	0.995	0.005
E20.9 Hypoparathyroidism, unspecified	0.004	0.995	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.005	0.995	0.000
K51.8 Other ulcerative colitis	0.005	0.995	0.000
E29.8 Other testicular dysfunction	0.004	0.995	0.000
E29.0 Testicular hyperfunction	0.004	0.995	0.000
E29.9 Testicular dysfunction, unspecified	0.004	0.995	0.000
E34 Other endocrine disorders	0.004	0.996	0.000
E24 Cushing's syndrome	0.004	0.996	0.000
E23.7 Disorder of pituitary gland, unspecified	0.004	0.996	0.000
E27.8 Other specified disorders of adrenal gland	0.004	0.996	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.000	0.996	0.004
J98.8 Other specified respiratory disorders	0.000	0.996	0.004
E28 Ovarian dysfunction	0.004	0.996	0.000
M84.09 Malunion of fracture (Site unspecified)	0.004	0.996	0.000
M84.00 Malunion of fracture (Multiple sites)	0.004	0.996	0.000
M25.54 Pain in joint (Hand)	0.000	0.996	0.004
E20.8 Other hypoparathyroidism	0.004	0.996	0.000
E32.8 Other diseases of thymus	0.004	0.996	0.000
J98.5 Diseases of mediastinum, not elsewhere classified	0.000	0.996	0.004
M84.08 Malunion of fracture (Other)	0.004	0.996	0.000
E31.0 Autoimmune polyglandular failure	0.004	0.996	0.000
J98.2 Interstitial emphysema	0.000	0.996	0.004
M84.02 Malunion of fracture (Upper arm)	0.004	0.996	0.000
E20.1 Pseudohypoparathyroidism	0.004	0.996	0.000
E20.0 Idiopathic hypoparathyroidism	0.004	0.996	0.000
E32.9 Disease of thymus, unspecified	0.004	0.996	0.000
M84.01 Malunion of fracture (Shoulder region)	0.004	0.996	0.000
E32.1 Abscess of thymus	0.004	0.996	0.000
E32.0 Persistent hyperplasia of thymus	0.004	0.996	0.000
K11.6 Mucocele of salivary gland	0.004	0.996	0.000
J98.3 Compensatory emphysema	0.000	0.996	0.004
E31.9 Polyglandular dysfunction, unspecified	0.004	0.996	0.000
E31.8 Other polyglandular dysfunction	0.004	0.996	0.000
E31.1 Polyglandular hyperfunction	0.004	0.996	0.000
N93.0 Postcoital and contact bleeding	0.000	0.996	0.004
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.004	0.996	0.000
K11.2 Sialoadenitis	0.004	0.996	0.000
E26.0 Primary hyperaldosteronism	0.004	0.996	0.000
E34.8 Other specified endocrine disorders	0.004	0.996	0.000
J98.6 Disorders of diaphragm	0.000	0.996	0.004
S72.00 Fracture of neck of femur (closed)	0.004	0.996	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.004	0.996	0.000
E30.9 Disorder of puberty, unspecified	0.003	0.996	0.000
E30.8 Other disorders of puberty	0.003	0.996	0.000
E30.1 Precocious puberty	0.003	0.996	0.000
E30.0 Delayed puberty	0.003	0.996	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.003	0.996	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.003	0.996	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.003	0.996	0.000
E26.8 Other hyperaldosteronism	0.003	0.996	0.000
E26.1 Secondary hyperaldosteronism	0.003	0.996	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.000	0.996	0.004
E24.0 Pituitary-dependent Cushing's disease	0.003	0.996	0.000
E25.9 Adrenogenital disorder, unspecified	0.003	0.996	0.000
E25.8 Other adrenogenital disorders	0.003	0.996	0.000
E34.9 Endocrine disorder, unspecified	0.003	0.996	0.000
E28.3 Primary ovarian failure	0.003	0.996	0.000
E24.9 Cushing's syndrome, unspecified	0.003	0.996	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.003	0.996	0.000
E24.3 Ectopic ACTH syndrome	0.003	0.996	0.000
E24.1 Nelson's syndrome	0.003	0.996	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.003	0.997	0.000
E26.9 Hyperaldosteronism, unspecified	0.003	0.997	0.000
E34.5 Androgen resistance syndrome	0.003	0.997	0.000
E34.4 Constitutional tall stature	0.003	0.997	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.003	0.997	0.000
E34.1 Other hypersecretion of intestinal hormones	0.003	0.997	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.003	0.997	0.000
E24.8 Other Cushing's syndrome	0.003	0.997	0.000
E34.3 Short stature, not elsewhere classified	0.003	0.997	0.000
E28.9 Ovarian dysfunction, unspecified	0.003	0.997	0.000
E28.8 Other ovarian dysfunction	0.003	0.997	0.000
E28.1 Androgen excess	0.003	0.997	0.000
E28.0 Oestrogen excess	0.003	0.997	0.000
E21.4 Other specified disorders of parathyroid gland	0.003	0.997	0.000
E21.2 Other hyperparathyroidism	0.003	0.997	0.000
L03.2 Cellulitis of face	0.003	0.997	0.000
K11 Diseases of salivary glands	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.003	0.997	0.000
D68.0 Von Willebrand's disease	0.003	0.997	0.000
S72.0 Fracture of neck of femur	0.003	0.997	0.000
K11.5 Sialolithiasis	0.003	0.997	0.000
S70.0 Contusion of hip	0.003	0.997	0.000
E24.2 Drug-induced Cushing's syndrome	0.003	0.997	0.000
E22.0 Acromegaly and pituitary gigantism	0.003	0.997	0.000
K11.3 Abscess of salivary gland	0.003	0.997	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.003	0.997	0.000
S70 Superficial injury of hip and thigh	0.003	0.997	0.000
S70.1 Contusion of thigh	0.003	0.997	0.000
S72 Fracture of femur	0.003	0.997	0.000
R54 Senility	0.003	0.997	0.000
K11.8 Other diseases of salivary glands	0.003	0.997	0.000
G06.1 Intraspinal abscess and granuloma	0.003	0.997	0.000
S72.2 Subtrochanteric fracture	0.003	0.997	0.000
S72.20 Subtrochanteric fracture (closed)	0.003	0.997	0.000
E34.0 Carcinoid syndrome	0.002	0.997	0.000
D68.8 Other specified coagulation defects	0.003	0.997	0.000
K11.0 Atrophy of salivary gland	0.003	0.997	0.000
E22.8 Other hyperfunction of pituitary gland	0.002	0.997	0.000
K11.4 Fistula of salivary gland	0.003	0.997	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.003	0.997	0.000
S72.3 Fracture of shaft of femur	0.003	0.997	0.000
M10.96 Gout, unspecified (Lower leg)	0.003	0.997	0.000
S72.01 Fracture of neck of femur (open)	0.002	0.997	0.000
S72.4 Fracture of lower end of femur	0.003	0.997	0.000
F06.7 Mild cognitive disorder	0.000	0.997	0.003
E21.3 Hyperparathyroidism, unspecified	0.003	0.997	0.000
L03.9 Cellulitis, unspecified	0.003	0.997	0.000
Z04.9 Examination and observation for unspecified reason	0.000	0.997	0.003
J98.0 Diseases of bronchus, not elsewhere classified	0.000	0.997	0.003
S72.40 Fracture of lower end of femur (closed)	0.003	0.997	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.997	0.000
E28.2 Polycystic ovarian syndrome	0.002	0.997	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.002	0.997	0.000
D68 Other coagulation defects	0.003	0.997	0.000
D68.5 Primary Thrombophilia	0.002	0.998	0.000
Y83.9 Surgical procedure, unspecified	0.002	0.998	0.000
S72.30 Fracture of shaft of femur (closed)	0.002	0.998	0.000
N93 Other abnormal uterine and vaginal bleeding	0.000	0.998	0.002
K11.9 Disease of salivary gland, unspecified	0.002	0.998	0.000
R57.0 Cardiogenic shock	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
A04.5 Campylobacter enteritis	0.002	0.998	0.000
S70.8 Other superficial injuries of hip and thigh	0.002	0.998	0.000
S72.7 Multiple fractures of femur	0.002	0.998	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.998	0.002
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.000	0.998	0.002
S72.21 Subtrochanteric fracture (open)	0.002	0.998	0.000
K11.7 Disturbances of salivary secretion	0.002	0.998	0.000
S72.8 Fractures of other parts of femur	0.002	0.998	0.000
H49.0 Third [oculomotor] nerve palsy	0.002	0.998	0.000
S72.31 Fracture of shaft of femur (open)	0.002	0.998	0.000
L03 Cellulitis	0.002	0.998	0.000
D68.1 Hereditary factor XI deficiency	0.002	0.998	0.000
N93.8 Other specified abnormal uterine and vaginal bleeding	0.000	0.998	0.002
S72.9 Fracture of femur, part unspecified	0.002	0.998	0.000
I45.6 Preexcitation syndrome	0.000	0.998	0.002
K29.0 Acute haemorrhagic gastritis	0.002	0.998	0.000
K11.1 Hypertrophy of salivary gland	0.002	0.998	0.000
L03.0 Cellulitis of finger and toe	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.002	0.998	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.002	0.998	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.002	0.998	0.000
E22.1 Hyperprolactinaemia	0.002	0.998	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.002	0.998	0.000
S70-S79 Injuries to the hip and thigh	0.002	0.998	0.000
S72.41 Fracture of lower end of femur (open)	0.002	0.998	0.000
D68.4 Acquired coagulation factor deficiency	0.002	0.998	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.998	0.002
S72.71 Multiple fractures of femur (open)	0.002	0.998	0.000
S72.70 Multiple fractures of femur (closed)	0.002	0.998	0.000
G44.2 Tension-type headache	0.002	0.998	0.000
L03.3 Cellulitis of trunk	0.002	0.998	0.000
S72.81 Fractures of other parts of femur (open)	0.002	0.998	0.000
S72.1 Pertrochanteric fracture	0.002	0.998	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.000	0.998	0.002
N95.3 States associated with artificial menopause	0.000	0.998	0.002
M18.1 Other primary arthrosis of first carpometacarpal joint	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.002	0.998	0.000
S72.91 Fracture of femur, part unspecified (open)	0.002	0.998	0.000
L03.8 Cellulitis of other sites	0.002	0.998	0.000
S72.80 Fractures of other parts of femur (closed)	0.002	0.998	0.000
I05.0 Mitral stenosis	0.002	0.998	0.000
Z03.3 Observation for suspected nervous system disorder	0.000	0.998	0.002
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.002	0.998	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.002	0.998	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.002	0.998	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.002	0.998	0.000
I89.0 Lymphoedema, not elsewhere classified	0.000	0.998	0.002
S78 Traumatic amputation of hip and thigh	0.002	0.998	0.000
S77 Crushing injury of hip and thigh	0.002	0.998	0.000
S79 Other and unspecified injuries of hip and thigh	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
S75 Injury of blood vessels at hip and thigh level	0.002	0.998	0.000
S74 Injury of nerves at hip and thigh level	0.002	0.998	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.001	0.998	0.000
S72.11 Pertrochanteric fracture (open)	0.001	0.998	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.002	0.998	0.000
K74.3 Primary biliary cirrhosis	0.000	0.998	0.002
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.000	0.998	0.002
S72.90 Fracture of femur, part unspecified (closed)	0.001	0.998	0.000
H83.0 Labyrinthitis	0.000	0.998	0.002
R50.0 Fever with chills	0.002	0.998	0.000
G06.2 Extradural and subdural abscess, unspecified	0.001	0.998	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.002	0.998	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
J43.9 Emphysema, unspecified	0.000	0.998	0.002
N95 Menopausal and other perimenopausal disorders	0.000	0.998	0.002
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.001
S76.1 Injury of quadriceps muscle and tendon	0.001	0.998	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.001	0.998	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.001	0.998	0.000
S79.9 Unspecified injury of hip and thigh	0.001	0.998	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.001
D68.2 Hereditary deficiency of other clotting factors	0.001	0.998	0.000
S77.2 Crushing injury of hip with thigh	0.001	0.998	0.000
S77.1 Crushing injury of thigh	0.001	0.998	0.000
S77.0 Crushing injury of hip	0.001	0.998	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.001	0.998	0.000
S78.1 Traumatic amputation at level between hip and knee	0.001	0.998	0.000
S78.0 Traumatic amputation at hip joint	0.001	0.998	0.000
D69.0 Allergic purpura	0.001	0.998	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.000	0.998	0.001
S76.0 Injury of muscle and tendon of hip	0.001	0.998	0.000
S79.7 Multiple injuries of hip and thigh	0.001	0.998	0.000
D04.6 Skin of upper limb, including shoulder	0.000	0.998	0.001
R57.9 Shock, unspecified	0.001	0.998	0.000
S74.9 Injury of unspecified nerve at hip and thigh level	0.001	0.998	0.000
S74.8 Injury of other nerves at hip and thigh level	0.001	0.998	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.001	0.998	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.001	0.998	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.001	0.998	0.000
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.001	0.998	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.001	0.998	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.001	0.998	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.001	0.998	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.001	0.998	0.000
S71 Open wound of hip and thigh	0.001	0.998	0.000
K04.7 Periapical abscess without sinus	0.001	0.999	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.001	0.999	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.999	0.001
R25.1 Tremor, unspecified	0.000	0.999	0.001
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.001	0.999	0.000
C51.9 Vulva, unspecified	0.001	0.999	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.001	0.999	0.000
Q82.5 Congenital nonneoplastic naevus	0.000	0.999	0.001
S75.0 Injury of femoral artery	0.001	0.999	0.000
T59.8 Other specified gases, fumes and vapours	0.001	0.999	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.001	0.999	0.000
K74.0 Hepatic fibrosis	0.000	0.999	0.001
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.001	0.999	0.000
M20.3 Other deformity of hallux (acquired)	0.001	0.999	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.001	0.999	0.000
S79.8 Other specified injuries of hip and thigh	0.001	0.999	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.001	0.999	0.000
M10.90 Gout, unspecified (Multiple sites)	0.001	0.999	0.000
M10.9 Gout, unspecified	0.001	0.999	0.000
N05.8 Other	0.001	0.999	0.000
Z58.1 Exposure to air pollution	0.000	0.999	0.001
Q89.2 Congenital malformations of other endocrine glands	0.001	0.999	0.000
M18 Arthrosis of first carpometacarpal joint	0.001	0.999	0.000
J95-J99 Other diseases of the respiratory system	0.000	0.999	0.001
S76.10 Unspecified injury of quadriceps muscle, fascia and tendon	0.001	0.999	0.000
D35.2 Pituitary gland	0.001	0.999	0.000
M21.1 Varus deformity, not elsewhere classified	0.001	0.999	0.000
N18.3 Chronic kidney disease, stage 3	0.001	0.999	0.000
Q87.4 Marfan's syndrome	0.001	0.999	0.000
G06.0 Intracranial abscess and granuloma	0.001	0.999	0.000
N95.0 Postmenopausal bleeding	0.000	0.999	0.001
R22.1 Localised swelling, mass and lump, neck	0.000	0.999	0.001
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.000	0.999	0.001
N95.1 Menopausal and female climacteric states	0.000	0.999	0.001
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.001	0.999	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.001	0.999	0.000
M10.93 Gout, unspecified (Forearm)	0.001	0.999	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.999	0.001
K56.7 Ileus, unspecified	0.001	0.999	0.000
Q82.0 Hereditary lymphoedema	0.000	0.999	0.001
T59.9 Gases, fumes and vapours, unspecified	0.001	0.999	0.000
W94.8 Other specified place	0.000	0.999	0.001
R57 Shock, not elsewhere classified	0.001	0.999	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.999	0.001
H74.1 Adhesive middle ear disease	0.000	0.999	0.001
L73.2 Hidradenitis suppurativa	0.000	0.999	0.001
S71.7 Multiple open wounds of of hip and thigh	0.001	0.999	0.000
S71.0 Open wound of hip	0.001	0.999	0.000
M10.98 Gout, unspecified (Other)	0.001	0.999	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M10.91 Gout, unspecified (Shoulder region)	0.001	0.999	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.001	0.999	0.000
D37.5 Rectum	0.001	0.999	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.001	0.999	0.000
M84.8 Other disorders of continuity of bone	0.001	0.999	0.000
J96 Respiratory failure, not elsewhere classified	0.000	0.999	0.001
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.001	0.999	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.999	0.001
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.001	0.999	0.000
K74.5 Biliary cirrhosis, unspecified	0.000	0.999	0.001
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.001	0.999	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.001	0.999	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.001	0.999	0.000
R57.2 Septic shock	0.001	0.999	0.000
T39.0 Salicylates	0.000	0.999	0.001
W44.0 Home	0.000	0.999	0.001
C07 Malignant neoplasm of parotid gland	0.001	0.999	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.999	0.001
M84 Disorders of continuity of bone	0.001	0.999	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.001	0.999	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.001	0.999	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.001	0.999	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.001	0.999	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.001	0.999	0.000
C08.9 Major salivary gland, unspecified	0.001	0.999	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.001	0.999	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.999	0.001
G00.9 Bacterial meningitis, unspecified	0.001	0.999	0.000
I51.7 Cardiomegaly	0.001	0.999	0.000
M07.3 Other psoriatic arthropathies	0.001	0.999	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.001	0.999	0.001
M79.54 Residual foreign body in soft tissue (Hand)	0.001	0.999	0.000
C10.9 Oropharynx, unspecified	0.001	0.999	0.000
D68.9 Coagulation defect, unspecified	0.001	0.999	0.000
D69.4 Other primary thrombocytopenia	0.001	0.999	0.000
F06.3 Organic mood [affective] disorders	0.000	0.999	0.001
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.001	0.999	0.000
R57.8 Other shock	0.001	0.999	0.000
M79.56 Residual foreign body in soft tissue (Lower leg)	0.001	0.999	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.001	0.999	0.000
J99.0 Rheumatoid lung disease	0.000	0.999	0.001
T63.4 Venom of other arthropods	0.001	0.999	0.000
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.001	0.999	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M84.26 Delayed union of fracture (Lower leg)	0.001	0.999	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.999	0.001
I27.0 Primary pulmonary hypertension	0.001	0.999	0.000
M84.2 Delayed union of fracture	0.001	0.999	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.000	0.999	0.001
S73.1 Sprain and strain of hip	0.001	0.999	0.001
M79.53 Residual foreign body in soft tissue (Forearm)	0.001	0.999	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.001	0.999	0.000
M84.88 Other disorders of continuity of bone (Other)	0.001	0.999	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.001	0.999	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.001	0.999	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.001	0.999	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.001	0.999	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.001	0.999	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.001	0.999	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.000	0.999	0.001
F06.5 Organic dissociative disorder	0.000	0.999	0.001
F06.4 Organic anxiety disorder	0.000	0.999	0.001
F06.1 Organic catatonic disorder	0.000	0.999	0.001
F06.0 Organic hallucinosis	0.000	0.999	0.001
H20.9 Iridocyclitis, unspecified	0.000	0.999	0.001
J96.9 Respiratory failure, unspecified	0.000	0.999	0.001
J96.1 Chronic respiratory failure	0.000	0.999	0.001
J96.0 Acute respiratory failure	0.000	0.999	0.001
L11.0 Acquired keratosis follicularis	0.001	0.999	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.001	0.999	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.001	0.999	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.001	0.999	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.001	0.999	0.000
M10.92 Gout, unspecified (Upper arm)	0.001	0.999	0.000
H54.9 Unspecified visual impairment (binocular)	0.001	0.999	0.000
H74.4 Polyp of middle ear	0.000	0.999	0.001
J95.5 Postprocedural subglottic stenosis	0.000	0.999	0.001
M84.9 Disorder of continuity of bone, unspecified	0.001	0.999	0.000
N95.9 Menopausal and perimenopausal disorder, unspecified	0.000	0.999	0.001
R68.8 Other specified general symptoms and signs	0.001	0.999	0.000
M10.04 Idiopathic gout (Hand)	0.001	0.999	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.000	0.999	0.001
N05.1 Focal and segmental glomerular lesions	0.001	0.999	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.001	0.999	0.000
M84.28 Delayed union of fracture (Other)	0.001	0.999	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.001	0.999	0.000
M84.24 Delayed union of fracture (Hand)	0.001	0.999	0.000
M84.23 Delayed union of fracture (Forearm)	0.001	0.999	0.000
M84.22 Delayed union of fracture (Upper arm)	0.001	0.999	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.001	0.999	0.000
A49.9 Bacterial infection, unspecified	0.001	0.999	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.001	0.999	0.000
D69.1 Qualitative platelet defects	0.001	0.999	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.001	0.999	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.000	0.999	0.001
R76.0 Raised antibody titer	0.000	0.999	0.001
S73.0 Dislocation of hip	0.001	0.999	0.000
Z50.4 Psychotherapy, not elsewhere classified	0.000	0.999	0.001
G00 Bacterial meningitis, not elsewhere classified	0.001	0.999	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.001	0.999	0.000
J96.09 Acute respiratory failure; Type unspecified	0.000	0.999	0.001
J96.01 Acute respiratory failure; Type II [hypercapnic]	0.000	0.999	0.001
J96.00 Acute respiratory failure; Type I [hypoxic]	0.000	0.999	0.001
J96.19 Chronic respiratory failure; Type unspecified	0.000	0.999	0.001
J96.11 Chronic respiratory failure; Type II [hypercapnic]	0.000	0.999	0.001
J96.10 Chronic respiratory failure; Type I [hypoxic]	0.000	0.999	0.001
J96.99 Respiratory failure, unspecified; Type unspecified	0.000	0.999	0.001
J96.91 Respiratory failure unspecified; Type II [hypercapnic]	0.000	0.999	0.001
J96.90 Respiratory failure, unspecified; Type I [hypoxic]	0.000	0.999	0.001
M07.36 Other psoriatic arthropathies (Lower leg)	0.001	0.999	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.001	0.999	0.000
M10.06 Idiopathic gout (Lower leg)	0.001	0.999	0.000
M10.94 Gout, unspecified (Hand)	0.001	0.999	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.001	0.999	0.000
B19.9 Unspecified viral hepatitis without coma	0.001	0.999	0.000
Q82.2 Mastocytosis	0.000	0.999	0.001
S71.1 Open wound of thigh	0.001	0.999	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.999	0.001
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.001	0.999	0.000
Z00.5 Examination of potential donor of organ and tissue	0.000	0.999	0.001
D69 Purpura and other haemorrhagic conditions	0.001	0.999	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.999	0.001
K74 Fibrosis and cirrhosis of liver	0.000	0.999	0.001
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.000	0.999	0.001
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.000	0.999	0.001
M79.58 Residual foreign body in soft tissue (Other)	0.001	0.999	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
M84.21 Delayed union of fracture (Shoulder region)	0.001	0.999	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.001	0.999	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.001	0.999	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.001	0.999	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.001	0.999	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.001	0.999	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.001	0.999	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.001	0.999	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.001	0.999	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.001	0.999	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.999	0.001
C13.0 Postcricoid region	0.001	0.999	0.000
G00.8 Other bacterial meningitis	0.001	0.999	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.001	0.999	0.000
J95.9 Postprocedural respiratory disorder, unspecified	0.000	0.999	0.001
S99.9 Unspecified injury of ankle and foot	0.000	0.999	0.001
D66 Hereditary factor VIII deficiency	0.001	0.999	0.000
I62 Other nontraumatic intracranial haemorrhage	0.001	0.999	0.000
Y88 Sequelae of surgical and medical care as external cause	0.001	0.999	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.001	0.999	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.000	0.999	0.001
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.000	0.999	0.001
M79.52 Residual foreign body in soft tissue (Upper arm)	0.001	0.999	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.001	0.999	0.000
S72.10 Pertrochanteric fracture (closed)	0.001	0.999	0.000
C08.0 Submandibular gland	0.001	0.999	0.000
D69.8 Other specified haemorrhagic conditions	0.001	0.999	0.000
E21.0 Primary hyperparathyroidism	0.001	0.999	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.000	0.999	0.001
G00.3 Staphylococcal meningitis	0.001	0.999	0.000
G00.0 Haemophilus meningitis	0.001	0.999	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.999	0.001
H74.0 Tympanosclerosis	0.000	0.999	0.001
I05.9 Mitral valve disease, unspecified	0.001	0.999	0.000
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.000	0.999	0.001
M84.3 Stress fracture, not elsewhere classified	0.001	0.999	0.000
N25.9 Disorder resulting from impaired renal tubular function, unspecified	0.000	0.999	0.001
S62.8 Fracture of other and unspecified parts of wrist and hand	0.001	0.999	0.000
W19.3 Sports and athletics area	0.000	0.999	0.001
C08 Malignant neoplasm of other and unspecified major salivary glands	0.001	0.999	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.001	0.999	0.000
T59 Toxic effect of other gases, fumes and vapours	0.001	0.999	0.000
M07.38 Other psoriatic arthropathies (Other)	0.001	0.999	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.001	0.999	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.000	0.999	0.001
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.999	0.001
J95.4 Mendelson's syndrome	0.000	0.999	0.001
J95.3 Chronic pulmonary insufficiency following surgery	0.000	0.999	0.001
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.000	0.999	0.001
K74.4 Secondary biliary cirrhosis	0.000	0.999	0.001
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations