TreeWAS – Variant ID: rs6719561

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E80.4 Gilbert's syndrome	0.000	0.000	1.000
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.484	0.516
E80.6 Other disorders of bilirubin metabolism	0.000	0.549	0.451
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.630	0.370
E80.5 Crigler-Najjar syndrome	0.000	0.630	0.370
E80.3 Defects of catalase and peroxydase	0.000	0.630	0.370
E80.0 Hereditary erythropoietic porphyria	0.000	0.630	0.370
E80.2 Other porphyria	0.000	0.659	0.341
E80.1 Porphyria cutanea tarda	0.000	0.666	0.334
R17 Unspecified jaundice	0.000	0.829	0.171
C78.7 Secondary malignant neoplasm of liver	0.009	0.991	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.007	0.993	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.007	0.993	0.000
C78.2 Secondary malignant neoplasm of pleura	0.007	0.993	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.007	0.993	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.993	0.007
C78.0 Secondary malignant neoplasm of lung	0.006	0.994	0.000
H90 Conductive and sensorineural hearing loss	0.000	0.994	0.006
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.006	0.994	0.000
L29.0 Pruritus ani	0.000	0.994	0.006
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.995	0.005
H90.2 Conductive hearing loss, unspecified	0.000	0.995	0.005
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.005	0.995	0.000
D41.4 Bladder	0.000	0.995	0.005
C78.1 Secondary malignant neoplasm of mediastinum	0.005	0.995	0.000
L43.9 Lichen planus, unspecified	0.000	0.995	0.005
H90.3 Sensorineural hearing loss, bilateral	0.000	0.995	0.005
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.995	0.005
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.995	0.004
H95.1 Other disorders following mastoidectomy	0.000	0.995	0.005
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.996	0.004
K86.2 Cyst of pancreas	0.000	0.996	0.004
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.996	0.004
K51.4 Pseudopolyposis of colon	0.000	0.996	0.004
C78.4 Secondary malignant neoplasm of small intestine	0.004	0.996	0.000
K82.4 Cholesterolosis of gallbladder	0.000	0.996	0.004
I38 Endocarditis, valve unspecified	0.004	0.996	0.000
N41.0 Acute prostatitis	0.004	0.996	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.000	0.996	0.004
H90.5 Sensorineural hearing loss, unspecified	0.000	0.996	0.004
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.004	0.996	0.000
H90.0 Conductive hearing loss, bilateral	0.000	0.996	0.003
S91.3 Open wound of other parts of foot	0.000	0.996	0.004
Q61.2 Polycystic kidney, adult type	0.000	0.997	0.003
L42 Pityriasis rosea	0.000	0.997	0.003
L43 Lichen planus	0.000	0.997	0.003
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.997	0.003
Z51.0 Radiotherapy session	0.003	0.997	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.000	0.997	0.003
D35.0 Adrenal gland	0.000	0.997	0.003
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.997	0.003
G04 Encephalitis, myelitis and encephalomyelitis	0.003	0.997	0.000
K86 Other diseases of pancreas	0.000	0.997	0.003
S91 Open wound of ankle and foot	0.000	0.997	0.003
F00 Dementia in Alzheimer's disease	0.000	0.997	0.003
S91.1 Open wound of toe(s) without damage to nail	0.000	0.997	0.003
H81.0 Meniere's disease	0.000	0.997	0.003
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.000	0.997	0.003
H95.8 Other postprocedural disorders of ear and mastoid process	0.000	0.997	0.003
D41.0 Kidney	0.000	0.997	0.003
K86.3 Pseudocyst of pancreas	0.000	0.997	0.003
S91.0 Open wound of ankle	0.000	0.997	0.003
H90-H95 Other disorders of ear	0.000	0.997	0.003
Z58.1 Exposure to air pollution	0.000	0.997	0.003
N41 Inflammatory diseases of prostate	0.003	0.997	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.997	0.003
D41.2 Ureter	0.000	0.997	0.003
D48.5 Skin	0.000	0.997	0.003
S80.0 Contusion of knee	0.003	0.997	0.000
K86.8 Other specified diseases of pancreas	0.000	0.997	0.003
L43.3 Subacute (active) lichen planus	0.000	0.997	0.003
L43.2 Lichenoid drug reaction	0.000	0.997	0.003
L43.1 Bullous lichen planus	0.000	0.997	0.003
L43.0 Hypertrophic lichen planus	0.000	0.997	0.003
L43.8 Other lichen planus	0.000	0.997	0.003
M16.0 Primary coxarthrosis, bilateral	0.003	0.997	0.000
D41.9 Urinary organ, unspecified	0.000	0.997	0.002
D41.7 Other urinary organs	0.000	0.997	0.002
D41.3 Urethra	0.000	0.997	0.002
D41.1 Renal pelvis	0.000	0.997	0.002
N41.8 Other inflammatory diseases of prostate	0.003	0.997	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.997	0.002
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.002	0.997	0.000
G04.1 Tropical spastic paraplegia	0.002	0.997	0.000
G04.0 Acute disseminated encephalitis	0.002	0.997	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.003	0.997	0.000
N41.1 Chronic prostatitis	0.003	0.997	0.000
N41.2 Abscess of prostate	0.002	0.997	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.997	0.002
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.997	0.002
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.002	0.998	0.000
I31.3 Pericardial effusion (noninflammatory)	0.000	0.998	0.002
K86.1 Other chronic pancreatitis	0.000	0.998	0.002
S00.7 Multiple superficial injuries of head	0.002	0.998	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.000	0.998	0.002
H93 Other disorders of ear, not elsewhere classified	0.000	0.998	0.002
M12.39 Palindromic rheumatism (Site unspecified)	0.002	0.998	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.000	0.998	0.002
N41.3 Prostatocystitis	0.002	0.998	0.000
N36.9 Urethral disorder, unspecified	0.000	0.998	0.002
N36.0 Urethral fistula	0.000	0.998	0.002
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.998	0.002
R07.0 Pain in throat	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.000	0.998	0.002
L40-L45 Papulosquamous disorders	0.000	0.998	0.002
C34.3 Lower lobe, bronchus or lung	0.002	0.998	0.000
H93.9 Disorder of ear, unspecified	0.000	0.998	0.002
M77.91 Enthesopathy, unspecified (Shoulder region)	0.000	0.998	0.002
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.998	0.002
H93.3 Disorders of acoustic nerve	0.000	0.998	0.002
Q61 Cystic kidney disease	0.000	0.998	0.002
M65.84 Other synovitis and tenosynovitis (Hand)	0.000	0.998	0.002
K86.9 Disease of pancreas, unspecified	0.000	0.998	0.002
N36.1 Urethral diverticulum	0.000	0.998	0.002
Z50.5 Speech therapy	0.002	0.998	0.000
H49.9 Paralytic strabismus, unspecified	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.998	0.002
H49.4 Progressive external ophthalmoplegia	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.000	0.998	0.002
N36 Other disorders of urethra	0.000	0.998	0.002
D26.0 Cervix uteri	0.000	0.998	0.002
N36.2 Urethral caruncle	0.000	0.998	0.002
H49.2 Sixth [abducent] nerve palsy	0.002	0.998	0.000
H49 Paralytic strabismus	0.002	0.998	0.000
H93.0 Degenerative and vascular disorders of ear	0.000	0.998	0.002
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.998	0.002
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.000	0.998	0.002
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
E70-E90 Metabolic disorders	0.000	0.998	0.002
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.000	0.998	0.002
E85.9 Amyloidosis, unspecified	0.000	0.998	0.002
S14.1 Other and unspecified injuries of cervical spinal cord	0.000	0.998	0.002
E85 Amyloidosis	0.000	0.998	0.002
I49.9 Cardiac arrhythmia, unspecified	0.002	0.998	0.000
L44 Other papulosquamous disorders	0.000	0.998	0.002
L41 Parapsoriasis	0.000	0.998	0.002
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.998	0.002
M25.86 Other specified joint disorders (Lower leg)	0.002	0.998	0.000
H93.2 Other abnormal auditory perceptions	0.000	0.998	0.002
E74 Other disorders of carbohydrate metabolism	0.000	0.998	0.002
Z97.4 Presence of external hearing-aid	0.000	0.998	0.002
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.998	0.002
R30.9 Painful micturition, unspecified	0.000	0.998	0.002
M62.26 Ischaemic infarction of muscle (Lower leg)	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.002	0.998	0.000
H93.1 Tinnitus	0.000	0.998	0.002
Q54.9 Hypospadias, unspecified	0.000	0.998	0.002
Q61.8 Other cystic kidney diseases	0.000	0.998	0.002
Q61.4 Renal dysplasia	0.000	0.998	0.002
Q61.1 Polycystic kidney, infantile type	0.000	0.998	0.002
M54.89 Other dorsalgia (Site unspecified)	0.002	0.998	0.000
M12.30 Palindromic rheumatism (Multiple sites)	0.002	0.998	0.000
E85.3 Secondary systemic amyloidosis	0.000	0.998	0.002
M12.3 Palindromic rheumatism	0.002	0.998	0.000
E84 Cystic fibrosis	0.000	0.998	0.002
E89.0 Postprocedural hypothyroidism	0.000	0.998	0.002
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.000	0.998	0.002
M10.96 Gout, unspecified (Lower leg)	0.002	0.998	0.000
H49.8 Other paralytic strabismus	0.002	0.998	0.000
H49.3 Total (external) ophthalmoplegia	0.002	0.998	0.000
H49.0 Third [oculomotor] nerve palsy	0.002	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.002	0.998	0.000
E79 Disorders of purine and pyrimidine metabolism	0.000	0.998	0.002
Q05.9 Spina bifida, unspecified	0.000	0.998	0.002
E77 Disorders of glycoprotein metabolism	0.000	0.998	0.002
E76 Disorders of glycosaminoglycan metabolism	0.000	0.998	0.002
E72 Other disorders of amino-acid metabolism	0.000	0.998	0.002
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.998	0.002
E70 Disorders of aromatic amino-acid metabolism	0.000	0.998	0.002
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.998	0.002
M62.83 Other specified disorders of muscle (Forearm)	0.002	0.998	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.002	0.998	0.000
H80.9 Otosclerosis, unspecified	0.000	0.998	0.002
M65.8 Other synovitis and tenosynovitis	0.000	0.998	0.002
N49.2 Inflammatory disorders of scrotum	0.002	0.998	0.000
Q85.9 Phakomatosis, unspecified	0.002	0.998	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.998	0.002
E85.8 Other amyloidosis	0.000	0.998	0.002
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.998	0.002
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.998	0.002
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.998	0.002
H93.8 Other specified disorders of ear	0.000	0.998	0.002
L41.9 Parapsoriasis, unspecified	0.000	0.998	0.001
L41.8 Other parapsoriasis	0.000	0.998	0.001
L41.5 Retiform parapsoriasis	0.000	0.998	0.001
L41.4 Large plaque parapsoriasis	0.000	0.998	0.001
L41.3 Small plaque parapsoriasis	0.000	0.998	0.001
L41.2 Lymphomatoid papulosis	0.000	0.998	0.001
L41.1 Pityriasis lichenoides chronica	0.000	0.998	0.001
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.998	0.001
L44.9 Papulosquamous disorder, unspecified	0.000	0.998	0.001
L44.8 Other specified papulosquamous disorders	0.000	0.998	0.001
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.998	0.001
L44.3 Lichen ruber moniliformis	0.000	0.998	0.001
L44.2 Lichen striatus	0.000	0.998	0.001
L44.1 Lichen nitidus	0.000	0.998	0.001
L44.0 Pityriasis rubra pilaris	0.000	0.998	0.001
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.002	0.998	0.000
M62.2 Ischaemic infarction of muscle	0.002	0.998	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.998	0.001
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.998	0.001
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.998	0.001
E74.2 Disorders of galactose metabolism	0.000	0.998	0.001
E74.1 Disorders of fructose metabolism	0.000	0.998	0.001
L71.9 Rosacea, unspecified	0.000	0.998	0.002
S90.0 Contusion of ankle	0.000	0.998	0.002
E84.9 Cystic fibrosis, unspecified	0.000	0.998	0.001
N36.8 Other specified disorders of urethra	0.000	0.998	0.002
Q61.9 Cystic kidney disease, unspecified	0.000	0.998	0.001
Q85.1 Tuberous sclerosis	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.000	0.998	0.002
E74.0 Glycogen storage disease	0.000	0.998	0.001
S99.8 Other specified injuries of ankle and foot	0.000	0.998	0.002
G93.0 Cerebral cysts	0.001	0.998	0.000
I97.1 Other functional disturbances following cardiac surgery	0.002	0.998	0.000
T85.2 Mechanical complication of intraocular lens	0.002	0.998	0.000
Q82 Other congenital malformations of skin	0.002	0.998	0.000
M12.38 Palindromic rheumatism (Other)	0.001	0.998	0.000
M12.37 Palindromic rheumatism (Ankle and foot)	0.001	0.998	0.000
M12.36 Palindromic rheumatism (Lower leg)	0.001	0.998	0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.001	0.998	0.000
M12.34 Palindromic rheumatism (Hand)	0.001	0.998	0.000
M12.33 Palindromic rheumatism (Forearm)	0.001	0.998	0.000
M12.32 Palindromic rheumatism (Upper arm)	0.001	0.998	0.000
M12.31 Palindromic rheumatism (Shoulder region)	0.001	0.998	0.000
M62.08 Diastasis of muscle (Other)	0.001	0.998	0.000
C16.3 Pyloric antrum	0.002	0.998	0.000
E84.8 Cystic fibrosis with other manifestations	0.000	0.998	0.001
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.998	0.001
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.998	0.001
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
Q82.5 Congenital nonneoplastic naevus	0.001	0.998	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.001	0.998	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.998	0.002
E85.4 Organ-limited amyloidosis	0.000	0.998	0.001
M62.0 Diastasis of muscle	0.001	0.998	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.002	0.998	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.998	0.001
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.998	0.001
E79.1 Lesch-Nyhan syndrome	0.000	0.998	0.001
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.998	0.001
S12.7 Multiple fractures of cervical spine	0.000	0.998	0.001
M62 Other disorders of muscle	0.001	0.998	0.000
M60.89 Other myositis (Site unspecified)	0.001	0.998	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.001	0.998	0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.000	0.998	0.001
M65.88 Other synovitis and tenosynovitis (Other)	0.000	0.998	0.001
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.000	0.998	0.001
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.000	0.998	0.001
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.000	0.998	0.001
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.998	0.001
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.998	0.001
E70.3 Albinism	0.000	0.998	0.001
E70.2 Disorders of tyrosine metabolism	0.000	0.998	0.001
E70.1 Other hyperphenylalaninaemias	0.000	0.998	0.001
E70.0 Classical phenylketonuria	0.000	0.998	0.001
E71.3 Disorders of fatty-acid metabolism	0.000	0.998	0.001
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.998	0.001
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.998	0.001
E71.0 Maple-syrup-urine disease	0.000	0.998	0.001
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.998	0.001
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.998	0.001
E72.5 Disorders of glycine metabolism	0.000	0.998	0.001
E72.4 Disorders of ornithine metabolism	0.000	0.998	0.001
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.998	0.001
E72.2 Disorders of urea cycle metabolism	0.000	0.998	0.001
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.998	0.001
E72.0 Disorders of amino-acid transport	0.000	0.998	0.001
E75.6 Lipid storage disorder, unspecified	0.000	0.998	0.001
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.998	0.001
E75.3 Sphingolipidosis, unspecified	0.000	0.998	0.001
E75.2 Other sphingolipidosis	0.000	0.998	0.001
E75.1 Other gangliosidosis	0.000	0.998	0.001
E75.0 GM2 gangliosidosis	0.000	0.998	0.001
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.998	0.001
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.998	0.001
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.998	0.001
E76.2 Other mucopolysaccharidoses	0.000	0.998	0.001
E76.1 Mucopolysaccharidosis, type II	0.000	0.998	0.001
E76.0 Mucopolysaccharidosis, type I	0.000	0.998	0.001
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.998	0.001
E77.8 Other disorders of glycoprotein metabolism	0.000	0.998	0.001
E77.1 Defects in glycoprotein degradation	0.000	0.998	0.001
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.998	0.001
H54.9 Unspecified visual impairment (binocular)	0.000	0.998	0.002
H74.4 Polyp of middle ear	0.000	0.998	0.001
I08.1 Disorders of both mitral and tricuspid valves	0.002	0.998	0.000
K85.2 Alcohol-induced acute pancreatitis	0.000	0.998	0.001
M62.8 Other specified disorders of muscle	0.001	0.998	0.000
Q61.5 Medullary cystic kidney	0.000	0.998	0.001
S90 Superficial injury of ankle and foot	0.000	0.998	0.001
E75.5 Other lipid storage disorders	0.000	0.999	0.001
G93.8 Other specified disorders of brain	0.000	0.999	0.001
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.001	0.999	0.000
S90.3 Contusion of other and unspecified parts of foot	0.000	0.999	0.001
S90-S99 Injuries to the ankle and foot	0.000	0.999	0.001
M62.29 Ischaemic infarction of muscle (Site unspecified)	0.001	0.999	0.000
M62.28 Ischaemic infarction of muscle (Other)	0.001	0.999	0.000
M62.27 Ischaemic infarction of muscle (Ankle and foot)	0.001	0.999	0.000
M62.25 Ischaemic infarction of muscle (Pelvic region and thigh)	0.001	0.999	0.000
M62.24 Ischaemic infarction of muscle (Hand)	0.001	0.999	0.000
M62.23 Ischaemic infarction of muscle (Forearm)	0.001	0.999	0.000
M62.22 Ischaemic infarction of muscle (Upper arm)	0.001	0.999	0.000
M62.21 Ischaemic infarction of muscle (Shoulder region)	0.001	0.999	0.000
M62.20 Ischaemic infarction of muscle (Multiple sites)	0.001	0.999	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
S99 Other and unspecified injuries of ankle and foot	0.000	0.999	0.001
Q82.0 Hereditary lymphoedema	0.001	0.999	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.999	0.001
M54.86 Other dorsalgia (Lumbar region)	0.001	0.999	0.000
M77.9 Enthesopathy, unspecified	0.000	0.999	0.001
Q82.2 Mastocytosis	0.001	0.999	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.001	0.999	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.001	0.999	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.000	0.999	0.001
M77.94 Enthesopathy, unspecified (Hand)	0.000	0.999	0.001
M62.9 Disorder of muscle, unspecified	0.001	0.999	0.000
M77.4 Metatarsalgia	0.000	0.999	0.001
S51.8 Open wound of other parts of forearm	0.001	0.999	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M62.84 Other specified disorders of muscle (Hand)	0.001	0.999	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.999	0.001
M60.8 Other myositis	0.001	0.999	0.000
Q82.9 Congenital malformation of skin, unspecified	0.001	0.999	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.001	0.999	0.000
Q82.3 Incontinentia pigmenti	0.001	0.999	0.000
Q82.1 Xeroderma pigmentosum	0.001	0.999	0.000
Z90.7 Acquired absence of genital organ(s)	0.001	0.999	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.001	0.999	0.000
A41.8 Other specified septicaemia	0.000	0.999	0.001
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.001	0.999	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.001	0.999	0.000
G93.4 Encephalopathy, unspecified	0.000	0.999	0.001
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.999	0.001
N60.8 Other benign mammary dysplasias	0.001	0.999	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.999	0.001
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.999	0.001
E73 Lactose intolerance	0.000	0.999	0.001
M62.09 Diastasis of muscle (Site unspecified)	0.001	0.999	0.000
M62.07 Diastasis of muscle (Ankle and foot)	0.001	0.999	0.000
M62.06 Diastasis of muscle (Lower leg)	0.001	0.999	0.000
M62.05 Diastasis of muscle (Pelvic region and thigh)	0.001	0.999	0.000
M62.04 Diastasis of muscle (Hand)	0.001	0.999	0.000
M62.03 Diastasis of muscle (Forearm)	0.001	0.999	0.000
M62.02 Diastasis of muscle (Upper arm)	0.001	0.999	0.000
M62.01 Diastasis of muscle (Shoulder region)	0.001	0.999	0.000
M62.00 Diastasis of muscle (Multiple sites)	0.001	0.999	0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.000	0.999	0.001
M77.96 Enthesopathy, unspecified (Lower leg)	0.000	0.999	0.001
G06.0 Intracranial abscess and granuloma	0.001	0.999	0.000
M60.95 Myositis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
S12.71 Multiple fractures of cervical spine (open)	0.000	0.999	0.001
J11.1 Influenza with other respiratory manifestations, virus not identified	0.001	0.999	0.000
K82.3 Fistula of gallbladder	0.000	0.999	0.001
M62.4 Contracture of muscle	0.001	0.999	0.000
M62.3 Immobility syndrome (paraplegic)	0.001	0.999	0.000
N13.3 Other and unspecified hydronephrosis	0.000	0.999	0.001
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.999	0.001
S90.2 Contusion of toe(s) with damage to nail	0.000	0.999	0.001
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.999	0.001
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.999	0.001
M54.84 Other dorsalgia (Thoracic region)	0.001	0.999	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.001	0.999	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.999	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M62.99 Disorder of muscle, unspecified (Site unspecified)	0.001	0.999	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.001	0.999	0.000
M60.9 Myositis, unspecified	0.001	0.999	0.000
N36.3 Prolapsed urethral mucosa	0.000	0.999	0.001
N60.3 Fibrosclerosis of breast	0.001	0.999	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.001	0.999	0.000
S98 Traumatic amputation of ankle and foot	0.000	0.999	0.001
S95 Injury of blood vessels at ankle and foot level	0.000	0.999	0.001
S94 Injury of nerves at ankle and foot level	0.000	0.999	0.001
M60.96 Myositis, unspecified (Lower leg)	0.001	0.999	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.001	0.999	0.000
M54.8 Other dorsalgia	0.001	0.999	0.000
S80.9 Superficial injury of lower leg, unspecified	0.001	0.999	0.000
S99.7 Multiple injuries of ankle and foot	0.000	0.999	0.001
M60 Myositis	0.001	0.999	0.000
Z58 Problems related to physical environment	0.000	0.999	0.001
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M60.05 Infective myositis (Pelvic region and thigh)	0.001	0.999	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M62.88 Other specified disorders of muscle (Other)	0.001	0.999	0.000
M77.99 Enthesopathy, unspecified (Site unspecified)	0.000	0.999	0.001
M77.98 Enthesopathy, unspecified (Other)	0.000	0.999	0.001
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.000	0.999	0.001
M77.93 Enthesopathy, unspecified (Forearm)	0.000	0.999	0.001
M77.90 Enthesopathy, unspecified (Multiple sites)	0.000	0.999	0.001
M60.0 Infective myositis	0.001	0.999	0.000
S81.9 Open wound of lower leg, part unspecified	0.001	0.999	0.000
S81.0 Open wound of knee	0.001	0.999	0.000
V49.9 Car occupant [any] injured in unspecified traffic accident	0.001	0.999	0.000
V49.5 Passenger injured in collision with other and unspecified motor vehicles in traffic accident	0.001	0.999	0.000
G00 Bacterial meningitis, not elsewhere classified	0.001	0.999	0.000
S80 Superficial injury of lower leg	0.001	0.999	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.001	0.999	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.001	0.999	0.000
M62.98 Disorder of muscle, unspecified (Other)	0.001	0.999	0.000
M62.97 Disorder of muscle, unspecified (Ankle and foot)	0.001	0.999	0.000
M62.96 Disorder of muscle, unspecified (Lower leg)	0.001	0.999	0.000
M62.95 Disorder of muscle, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M62.94 Disorder of muscle, unspecified (Hand)	0.001	0.999	0.000
M62.93 Disorder of muscle, unspecified (Forearm)	0.001	0.999	0.000
M62.92 Disorder of muscle, unspecified (Upper arm)	0.001	0.999	0.000
M62.91 Disorder of muscle, unspecified (Shoulder region)	0.001	0.999	0.000
M62.90 Disorder of muscle, unspecified (Multiple sites)	0.001	0.999	0.000
M77.49 Metatarsalgia-Site unspec	0.000	0.999	0.001
M77.48 Metatarsalgia-Other	0.000	0.999	0.001
M77.46 Metatarsalgia-Lower Leg	0.000	0.999	0.001
M77.45 Metatarsalgia-Pelvic/Thigh	0.000	0.999	0.001
M77.44 Metatarsalgia-Hand	0.000	0.999	0.001
M77.43 Metatarsalgia-Forearm	0.000	0.999	0.001
M77.42 Metatarsalgia-Upper arm	0.000	0.999	0.001
M77.41 Metatarsalgia-Shldr region	0.000	0.999	0.001
M77.40 Metatarsalgia-Mult sites	0.000	0.999	0.001
H52.2 Astigmatism	0.001	0.999	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.001	0.999	0.000
S01.8 Open wound of other parts of head	0.001	0.999	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.001	0.999	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.001	0.999	0.000
M54.87 Other dorsalgia (Lumbosacral region)	0.001	0.999	0.000
M60.88 Other myositis (Other)	0.001	0.999	0.000
M60.87 Other myositis (Ankle and foot)	0.001	0.999	0.000
M60.86 Other myositis (Lower leg)	0.001	0.999	0.000
M60.85 Other myositis (Pelvic region and thigh)	0.001	0.999	0.000
M60.84 Other myositis (Hand)	0.001	0.999	0.000
M60.83 Other myositis (Forearm)	0.001	0.999	0.000
M60.82 Other myositis (Upper arm)	0.001	0.999	0.000
M60.81 Other myositis (Shoulder region)	0.001	0.999	0.000
M60.80 Other myositis (Multiple sites)	0.001	0.999	0.000
B20.3 HIV disease resulting in other viral infections	0.001	0.999	0.000
E73.8 Other lactose intolerance	0.000	0.999	0.001
E73.1 Secondary lactase deficiency	0.000	0.999	0.001
E73.0 Congenital lactase deficiency	0.000	0.999	0.001
G30.0 Alzheimer's disease with early onset	0.000	0.999	0.001
Z58.5 Exposure to other pollution	0.000	0.999	0.001
M54.80 Other dorsalgia (Multiple sites in spine)	0.001	0.999	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.000	0.999	0.001
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.999	0.001
C51.9 Vulva, unspecified	0.001	0.999	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.001	0.999	0.000
K82 Other diseases of gallbladder	0.000	0.999	0.001
M62.39 Immobility syndrome (paraplegic) (Site unspecified)	0.001	0.999	0.000
M62.38 Immobility syndrome (paraplegic) (Other)	0.001	0.999	0.000
M62.37 Immobility syndrome (paraplegic) (Ankle and foot)	0.001	0.999	0.000
M62.36 Immobility syndrome (paraplegic) (Lower leg)	0.001	0.999	0.000
M62.35 Immobility syndrome (paraplegic) (Pelvic region and thigh)	0.001	0.999	0.000
M62.34 Immobility syndrome (paraplegic) (Hand)	0.001	0.999	0.000
M62.33 Immobility syndrome (paraplegic) (Forearm)	0.001	0.999	0.000
M62.32 Immobility syndrome (paraplegic) (Upper arm)	0.001	0.999	0.000
M62.31 Immobility syndrome (paraplegic) (Shoulder region)	0.001	0.999	0.000
M62.30 Immobility syndrome (paraplegic) (Multiple sites)	0.001	0.999	0.000
M62.49 Contracture of muscle (Site unspecified)	0.001	0.999	0.000
M62.48 Contracture of muscle (Other)	0.001	0.999	0.000
M62.47 Contracture of muscle (Ankle and foot)	0.001	0.999	0.000
M62.46 Contracture of muscle (Lower leg)	0.001	0.999	0.000
M62.45 Contracture of muscle (Pelvic region and thigh)	0.001	0.999	0.000
M62.44 Contracture of muscle (Hand)	0.001	0.999	0.000
M62.43 Contracture of muscle (Forearm)	0.001	0.999	0.000
M62.42 Contracture of muscle (Upper arm)	0.001	0.999	0.000
M62.41 Contracture of muscle (Shoulder region)	0.001	0.999	0.000
M62.40 Contracture of muscle (Multiple sites)	0.001	0.999	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.999	0.001
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.999	0.001
E89.5 Postprocedural testicular hypofunction	0.000	0.999	0.001
G00.9 Bacterial meningitis, unspecified	0.001	0.999	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.999	0.001
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.999	0.001
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.999	0.001
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.999	0.001
S97 Crushing injury of ankle and foot	0.000	0.999	0.001
M24.07 Loose body in joint (Ankle and foot)	0.000	0.999	0.001
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M54.85 Other dorsalgia (Thoracolumbar region)	0.001	0.999	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.001	0.999	0.000
M54.82 Other dorsalgia (Cervical region)	0.001	0.999	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.001	0.999	0.000
M60.98 Myositis, unspecified (Other)	0.001	0.999	0.000
M60.97 Myositis, unspecified (Ankle and foot)	0.001	0.999	0.000
M60.94 Myositis, unspecified (Hand)	0.001	0.999	0.000
M60.93 Myositis, unspecified (Forearm)	0.001	0.999	0.000
M60.92 Myositis, unspecified (Upper arm)	0.001	0.999	0.000
M60.91 Myositis, unspecified (Shoulder region)	0.001	0.999	0.000
M60.90 Myositis, unspecified (Multiple sites)	0.001	0.999	0.000
E89.1 Postprocedural hypoinsulinaemia	0.000	0.999	0.001
G93.3 Postviral fatigue syndrome	0.000	0.999	0.001
I05.2 Mitral stenosis with insufficiency	0.001	0.999	0.000
K82.1 Hydrops of gallbladder	0.000	0.999	0.001
S90.1 Contusion of toe(s) without damage to nail	0.000	0.999	0.001
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations