TreeWAS – Variant ID: rs6747380

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R49.0 Dysphonia	0.020	0.980	0.000
F10.2 Dependence syndrome	0.019	0.981	0.000
F10.0 Acute intoxication	0.016	0.984	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.016	0.984	0.000
F10.9 Unspecified mental and behavioural disorder	0.016	0.984	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.000	0.984	0.016
I89.0 Lymphoedema, not elsewhere classified	0.015	0.985	0.000
F10.6 Amnesic syndrome	0.012	0.988	0.000
F10.5 Psychotic disorder	0.012	0.988	0.000
F10.8 Other mental and behavioural disorders	0.012	0.988	0.000
F10.7 Residual and late-onset psychotic disorder	0.012	0.988	0.000
D05 Carcinoma in situ of breast	0.000	0.989	0.011
D05.1 Intraductal carcinoma in situ	0.000	0.989	0.011
F10.4 Withdrawal state with delirium	0.010	0.990	0.000
D05.0 Lobular carcinoma in situ	0.000	0.990	0.010
Z57.2 Occupational exposure to dust	0.009	0.991	0.000
R41.0 Disorientation, unspecified	0.008	0.992	0.000
F10.3 Withdrawal state	0.008	0.992	0.000
R49 Voice disturbances	0.008	0.992	0.000
Z57 Occupational exposure to risk-factors	0.008	0.992	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.007	0.993	0.000
R52.1 Chronic intractable pain	0.007	0.993	0.000
D05.7 Other carcinoma in situ of breast	0.000	0.993	0.007
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.007	0.993	0.000
Z57.3 Occupational exposure to other air contaminants	0.006	0.994	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.006	0.994	0.000
R49.2 Hypernasality and hyponasality	0.006	0.994	0.000
R49.1 Aphonia	0.006	0.994	0.000
F13.2 Dependence syndrome	0.006	0.994	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.006	0.994	0.000
Z57.8 Occupational exposure to other risk-factors	0.006	0.994	0.000
Z57.7 Occupational exposure to vibration	0.006	0.994	0.000
Z57.6 Occupational exposure to extreme temperature	0.006	0.994	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.006	0.994	0.000
Z57.1 Occupational exposure to radiation	0.006	0.994	0.000
Z57.0 Occupational exposure to noise	0.006	0.994	0.000
C69.3 Choroid	0.000	0.994	0.006
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.006	0.994	0.000
Z63.8 Other specified problems related to primary support group	0.005	0.994	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.005	0.995	0.000
Z63 Other problems related to primary support group, including family circumstances	0.005	0.995	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.995	0.005
C56 Malignant neoplasm of ovary	0.000	0.995	0.005
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.005	0.995	0.000
Z56 Problems related to employment and unemployment	0.005	0.995	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.005	0.995	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.005	0.995	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.005	0.995	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.005	0.995	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.005	0.995	0.000
F11 Mental and behavioural disorders due to use of opioids	0.005	0.995	0.000
Z61 Problems related to negative life events in childhood	0.005	0.995	0.000
Z59 Problems related to housing and economic circumstances	0.005	0.995	0.000
W07.0 Home	0.005	0.995	0.000
Z63.6 Dependent relative needing care at home	0.005	0.995	0.000
R49.8 Other and unspecified voice disturbances	0.004	0.995	0.000
F13.9 Unspecified mental and behavioural disorder	0.004	0.995	0.000
F13.8 Other mental and behavioural disorders	0.004	0.995	0.000
F13.7 Residual and late-onset psychotic disorder	0.004	0.995	0.000
F13.6 Amnesic syndrome	0.004	0.995	0.000
F13.5 Psychotic disorder	0.004	0.995	0.000
F13.4 Withdrawal state with delirium	0.004	0.995	0.000
F13.3 Withdrawal state	0.004	0.995	0.000
F13.1 Harmful use	0.004	0.995	0.000
F13.0 Acute intoxication	0.004	0.995	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.005	0.995	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.005	0.995	0.000
Q60-Q64 Congenital malformations of the urinary system	0.005	0.995	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.004	0.995	0.000
Z63.5 Disruption of family by separation and divorce	0.004	0.995	0.000
C83.0 Small cell (diffuse)	0.004	0.996	0.000
Z56.0 Unemployment, unspecified	0.004	0.996	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.004	0.996	0.000
Z56.6 Other physical and mental strain related to work	0.004	0.996	0.000
C83.3 Large cell (diffuse)	0.004	0.996	0.000
Q38.7 Pharyngeal pouch	0.004	0.996	0.000
C90.0 Multiple myeloma	0.004	0.996	0.000
V23.4 Driver injured in traffic accident	0.000	0.996	0.004
Z65 Problems related to other psychosocial circumstances	0.004	0.996	0.000
Z62 Other problems related to upbringing	0.004	0.996	0.000
Z55 Problems related to education and literacy	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
C83.7 Burkitt's tumour	0.004	0.996	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.004	0.996	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.004	0.996	0.000
Z56.3 Stressful work schedule	0.004	0.996	0.000
F19.1 Harmful use	0.004	0.996	0.000
Q80-Q89 Other congenital malformations	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.004	0.996	0.000
F15.1 Harmful use	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
Z63.9 Problem related to primary support group, unspecified	0.004	0.996	0.000
Z63.3 Absence of family member	0.004	0.996	0.000
Z63.2 Inadequate family support	0.004	0.996	0.000
Z63.1 Problems in relationship with parents and in-laws	0.004	0.996	0.000
Z58 Problems related to physical environment	0.004	0.996	0.000
F19.2 Dependence syndrome	0.004	0.996	0.000
Z59.1 Inadequate housing	0.004	0.996	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.004	0.996	0.000
Q63 Other congenital malformations of kidney	0.004	0.996	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.004	0.996	0.000
F19.9 Unspecified mental and behavioural disorder	0.004	0.996	0.000
F19.8 Other mental and behavioural disorders	0.004	0.996	0.000
F19.7 Residual and late-onset psychotic disorder	0.004	0.996	0.000
F19.6 Amnesic syndrome	0.004	0.996	0.000
F19.5 Psychotic disorder	0.004	0.996	0.000
F19.4 Withdrawal state with delirium	0.004	0.996	0.000
F19.3 Withdrawal state	0.004	0.996	0.000
F19.0 Acute intoxication	0.004	0.996	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.004	0.996	0.000
Z56.7 Other and unspecified problems related to employment	0.004	0.996	0.000
Z56.5 Uncongenial work	0.004	0.996	0.000
Z56.4 Discord with boss and workmates	0.004	0.996	0.000
Z56.2 Threat of job loss	0.004	0.996	0.000
Z56.1 Change of job	0.004	0.996	0.000
F15.9 Unspecified mental and behavioural disorder	0.004	0.996	0.000
F15.8 Other mental and behavioural disorders	0.004	0.996	0.000
F15.7 Residual and late-onset psychotic disorder	0.004	0.996	0.000
F15.6 Amnesic syndrome	0.004	0.996	0.000
F15.5 Psychotic disorder	0.004	0.996	0.000
F15.4 Withdrawal state with delirium	0.004	0.996	0.000
F15.3 Withdrawal state	0.004	0.996	0.000
F15.2 Dependence syndrome	0.004	0.996	0.000
F15.0 Acute intoxication	0.004	0.996	0.000
Z61.6 Problems related to alleged physical abuse of child	0.004	0.996	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
F11.1 Harmful use	0.004	0.996	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.004	0.996	0.000
Q28 Other congenital malformations of circulatory system	0.004	0.996	0.000
Q24 Other congenital malformations of heart	0.004	0.996	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.004	0.996	0.000
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
F14.9 Unspecified mental and behavioural disorder	0.004	0.996	0.000
F14.8 Other mental and behavioural disorders	0.004	0.996	0.000
F14.7 Residual and late-onset psychotic disorder	0.004	0.996	0.000
F14.6 Amnesic syndrome	0.004	0.996	0.000
F14.5 Psychotic disorder	0.004	0.996	0.000
F14.4 Withdrawal state with delirium	0.004	0.996	0.000
F14.3 Withdrawal state	0.004	0.996	0.000
F14.2 Dependence syndrome	0.004	0.996	0.000
F14.1 Harmful use	0.004	0.996	0.000
F14.0 Acute intoxication	0.004	0.996	0.000
F16.9 Unspecified mental and behavioural disorder	0.004	0.996	0.000
F16.8 Other mental and behavioural disorders	0.004	0.996	0.000
F16.7 Residual and late-onset psychotic disorder	0.004	0.996	0.000
F16.6 Amnesic syndrome	0.004	0.996	0.000
F16.5 Psychotic disorder	0.004	0.996	0.000
F16.4 Withdrawal state with delirium	0.004	0.996	0.000
F16.3 Withdrawal state	0.004	0.996	0.000
F16.2 Dependence syndrome	0.004	0.996	0.000
F16.1 Harmful use	0.004	0.996	0.000
F16.0 Acute intoxication	0.004	0.996	0.000
F18.9 Unspecified mental and behavioural disorder	0.004	0.996	0.000
F18.8 Other mental and behavioural disorders	0.004	0.996	0.000
F18.7 Residual and late-onset psychotic disorder	0.004	0.996	0.000
F18.6 Amnesic syndrome	0.004	0.996	0.000
F18.5 Psychotic disorder	0.004	0.996	0.000
F18.4 Withdrawal state with delirium	0.004	0.996	0.000
F18.3 Withdrawal state	0.004	0.996	0.000
F18.2 Dependence syndrome	0.004	0.996	0.000
F18.1 Harmful use	0.004	0.996	0.000
F18.0 Acute intoxication	0.004	0.996	0.000
Q96 Turner's syndrome	0.004	0.996	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.004	0.996	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.004	0.996	0.000
Q35-Q37 Cleft lip and cleft palate	0.004	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
Q61 Cystic kidney disease	0.004	0.996	0.000
Q51 Congenital malformations of uterus and cervix	0.004	0.996	0.000
Q74 Other congenital malformations of limb(s)	0.004	0.996	0.000
Q21 Congenital malformations of cardiac septa	0.004	0.996	0.000
F11.9 Unspecified mental and behavioural disorder	0.003	0.996	0.000
F11.8 Other mental and behavioural disorders	0.003	0.996	0.000
F11.7 Residual and late-onset psychotic disorder	0.003	0.996	0.000
F11.6 Amnesic syndrome	0.003	0.996	0.000
F11.5 Psychotic disorder	0.003	0.996	0.000
F11.4 Withdrawal state with delirium	0.003	0.996	0.000
F11.3 Withdrawal state	0.003	0.996	0.000
F11.0 Acute intoxication	0.003	0.996	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.004	0.996	0.000
Z59.7 Insufficient social insurance and welfare support	0.004	0.996	0.000
Z59.6 Low income	0.004	0.996	0.000
Z59.5 Extreme poverty	0.004	0.996	0.000
Z59.4 Lack of adequate food	0.004	0.996	0.000
Z59.3 Problems related to living in residential institution	0.004	0.996	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.004	0.996	0.000
Z61.9 Negative life events in childhood, unspecified	0.004	0.996	0.000
Z61.8 Other negative life events in childhood	0.004	0.996	0.000
Z61.7 Personal frightening experience in childhood	0.004	0.996	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.004	0.996	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.004	0.996	0.000
Z61.2 Altered pattern of family relationships in childhood	0.004	0.996	0.000
Z61.1 Removal from home in childhood	0.004	0.996	0.000
Z61.0 Loss of love relationship in childhood	0.004	0.996	0.000
Q76 Congenital malformations of spine and bony thorax	0.004	0.996	0.000
Q85 Phakomatoses, not elsewhere classified	0.004	0.996	0.000
Z64 Problems related to certain psychosocial circumstances	0.003	0.996	0.000
Z63.4 Disappearance and death of family member	0.004	0.996	0.000
Q82 Other congenital malformations of skin	0.004	0.996	0.000
C83.1 Small cleaved cell (diffuse)	0.004	0.996	0.000
Q78 Other osteochondrodysplasias	0.004	0.996	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.004	0.996	0.000
Q96.9 Turner's syndrome, unspecified	0.003	0.996	0.000
H27.0 Aphakia	0.004	0.996	0.000
Q63.0 Accessory kidney	0.004	0.996	0.000
C83.6 Undifferentiated (diffuse)	0.003	0.996	0.000
C83.5 Lymphoblastic (diffuse)	0.003	0.996	0.000
C83.4 Immunoblastic (diffuse)	0.003	0.996	0.000
C83.2 Mixed small and large cell (diffuse)	0.003	0.996	0.000
Z59.0 Homelessness	0.003	0.996	0.000
Q64 Other congenital malformations of urinary system	0.003	0.996	0.000
Q61.3 Polycystic kidney, unspecified	0.004	0.996	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.996	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.003	0.996	0.000
Q51.2 Other doubling of uterus	0.003	0.996	0.000
Q62.1 Atresia and stenosis of ureter	0.003	0.996	0.000
Q76.0 Spina bifida occulta	0.003	0.996	0.000
Q55 Other congenital malformations of male genital organs	0.003	0.997	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.000	0.997	0.003
Q26 Congenital malformations of great veins	0.003	0.997	0.000
Q23 Congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q82.8 Other specified congenital malformations of skin	0.003	0.997	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.003	0.997	0.000
C69 Malignant neoplasm of eye and adnexa	0.000	0.997	0.003
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.003	0.997	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.003	0.997	0.000
Z55.8 Other problems relating to education and literacy	0.003	0.997	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.003	0.997	0.000
Z55.3 Underachievement in school	0.003	0.997	0.000
Z55.2 Failed examinations	0.003	0.997	0.000
Z55.1 Schooling unavailable and unattainable	0.003	0.997	0.000
Z55.0 Illiteracy and low-level literacy	0.003	0.997	0.000
Z62.9 Problem related to upbringing, unspecified	0.003	0.997	0.000
Z62.8 Other specified problems related to upbringing	0.003	0.997	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.003	0.997	0.000
Z62.5 Other problems related to neglect in upbringing	0.003	0.997	0.000
Z62.4 Emotional neglect of child	0.003	0.997	0.000
Z62.3 Hostility towards and scapegoating of child	0.003	0.997	0.000
Z62.2 Institutional upbringing	0.003	0.997	0.000
Z62.1 Parental overprotection	0.003	0.997	0.000
Z62.0 Inadequate parental supervision and control	0.003	0.997	0.000
Z63.7 Other stressful life events affecting family and household	0.003	0.997	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.003	0.997	0.000
Z65.8 Other specified problems related to psychosocial circumstances	0.003	0.997	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.003	0.997	0.000
Z65.4 Victim of crime and terrorism	0.003	0.997	0.000
Z65.3 Problems related to other legal circumstances	0.003	0.997	0.000
Z65.2 Problems related to release from prison	0.003	0.997	0.000
Z65.1 Imprisonment and other incarceration	0.003	0.997	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.003	0.997	0.000
O82.1 Delivery by emergency Caesarean section	0.000	0.997	0.003
C90.2 Plasmacytoma, extramedullary	0.003	0.997	0.000
L92.0 Granuloma annulare	0.000	0.997	0.003
Z58.8 Other problems related to physical environment	0.003	0.997	0.000
C90.3 Solitary plasmacytoma	0.003	0.997	0.000
Q62.5 Duplication of ureter	0.003	0.997	0.000
Z58.7 Exposure to tobacco smoke	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
Q90 Down's syndrome	0.003	0.997	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.003	0.997	0.000
Q79.6 Ehlers-Danlos syndrome	0.003	0.997	0.000
Q04 Other congenital malformations of brain	0.003	0.997	0.000
Q66 Congenital deformities of feet	0.003	0.997	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.003	0.997	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.003	0.997	0.000
Q24.8 Other specified congenital malformations of heart	0.003	0.997	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.000	0.997	0.003
C90.1 Plasma cell leukaemia	0.003	0.997	0.000
F12.9 Unspecified mental and behavioural disorder	0.003	0.997	0.000
F12.8 Other mental and behavioural disorders	0.003	0.997	0.000
F12.7 Residual and late-onset psychotic disorder	0.003	0.997	0.000
F12.6 Amnesic syndrome	0.003	0.997	0.000
F12.5 Psychotic disorder	0.003	0.997	0.000
F12.4 Withdrawal state with delirium	0.003	0.997	0.000
F12.3 Withdrawal state	0.003	0.997	0.000
F12.0 Acute intoxication	0.003	0.997	0.000
Q38.8 Other congenital malformations of pharynx	0.003	0.997	0.000
Q38.6 Other congenital malformations of mouth	0.003	0.997	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.003	0.997	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.003	0.997	0.000
Q38.3 Other congenital malformations of tongue	0.003	0.997	0.000
Q38.2 Macroglossia	0.003	0.997	0.000
Q38.1 Ankyloglossia	0.003	0.997	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.003	0.997	0.000
Z60 Problems related to social environment	0.003	0.997	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.997	0.003
Q03 Congenital hydrocephalus	0.003	0.997	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.003	0.997	0.000
K10.2 Inflammatory conditions of jaws	0.003	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.003	0.997	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.003	0.997	0.000
Q84 Other congenital malformations of integument	0.003	0.997	0.000
Q81 Epidermolysis bullosa	0.003	0.997	0.000
Q80 Congenital ichthyosis	0.003	0.997	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.003	0.997	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.003	0.997	0.000
Z50.0 Cardiac rehabilitation	0.000	0.997	0.003
Z58.9 Problem related to physical environment, unspecified	0.003	0.997	0.000
Z58.6 Inadequate drinking-water supply	0.003	0.997	0.000
Z58.5 Exposure to other pollution	0.003	0.997	0.000
Z58.4 Exposure to radiation	0.003	0.997	0.000
Z58.3 Exposure to soil pollution	0.003	0.997	0.000
Z58.2 Exposure to water pollution	0.003	0.997	0.000
Z58.0 Exposure to noise	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.003	0.997	0.000
Q52 Other congenital malformations of female genitalia	0.003	0.997	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.003	0.997	0.000
Q17 Other congenital malformations of ear	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
Q24.0 Dextrocardia	0.003	0.997	0.000
R41.3 Other amnesia	0.003	0.997	0.000
Q25 Congenital malformations of great arteries	0.003	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.003	0.997	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.003	0.997	0.000
Q62.6 Malposition of ureter	0.003	0.997	0.000
Q62.4 Agenesis of ureter	0.003	0.997	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.003	0.997	0.000
Q62.2 Congenital megaloureter	0.003	0.997	0.000
Q62.0 Congenital hydronephrosis	0.003	0.997	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.003	0.997	0.000
Q63.8 Other specified congenital malformations of kidney	0.003	0.997	0.000
Q63.3 Hyperplastic and giant kidney	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.003	0.997	0.000
C85.1 B-cell lymphoma, unspecified	0.003	0.997	0.000
C85.0 Lymphosarcoma	0.003	0.997	0.000
F12.2 Dependence syndrome	0.003	0.997	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q21.0 Ventricular septal defect	0.003	0.997	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.003	0.997	0.000
Q63.2 Ectopic kidney	0.003	0.997	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.003	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
Q15 Other congenital malformations of eye	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.997	0.000
C69.9 Eye, unspecified	0.000	0.997	0.003
Q28.0 Arteriovenous malformation of precerebral vessels	0.003	0.997	0.000
Q24.6 Congenital heart block	0.003	0.997	0.000
Q24.4 Congenital subaortic stenosis	0.003	0.997	0.000
Q24.3 Pulmonary infundibular stenosis	0.003	0.997	0.000
Q24.2 Cor triatriatum	0.003	0.997	0.000
Q24.1 Levocardia	0.003	0.997	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.003	0.997	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.003	0.997	0.000
Q28.3 Other malformations of cerebral vessels	0.003	0.997	0.000
Q28.1 Other malformations of precerebral vessels	0.003	0.997	0.000
F11.2 Dependence syndrome	0.003	0.997	0.000
Q61.9 Cystic kidney disease, unspecified	0.003	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.003	0.997	0.000
Q01 Encephalocele	0.003	0.997	0.000
Q00 Anencephaly and similar malformations	0.003	0.997	0.000
Q02 Microcephaly	0.003	0.997	0.000
Q53 Undescended testicle	0.003	0.997	0.000
Q66.9 Congenital deformity of feet, unspecified	0.003	0.997	0.000
Q74.1 Congenital malformation of knee	0.003	0.997	0.000
Q78.0 Osteogenesis imperfecta	0.003	0.997	0.000
Z82.3 Family history of stroke	0.003	0.997	0.000
Q55.6 Other congenital malformations of penis	0.003	0.997	0.000
Q96.8 Other variants of Turner's syndrome	0.003	0.997	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.003	0.997	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.003	0.997	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.003	0.997	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.003	0.997	0.000
Q96.0 Karyotype 45,X	0.003	0.997	0.000
Q24.5 Malformation of coronary vessels	0.003	0.997	0.000
Q12 Congenital lens malformations	0.003	0.997	0.000
Z63.0 Problems in relationship with spouse or partner	0.003	0.997	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.003	0.997	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.003	0.997	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.003	0.997	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.997	0.000
Q79.5 Other congenital malformations of abdominal wall	0.003	0.997	0.000
Q79.4 Prune belly syndrome	0.003	0.997	0.000
Q79.3 Gastroschisis	0.003	0.997	0.000
Q79.2 Exomphalos	0.003	0.997	0.000
Q79.1 Other congenital malformations of diaphragm	0.003	0.997	0.000
Q79.0 Congenital diaphragmatic hernia	0.003	0.997	0.000
Q61.8 Other cystic kidney diseases	0.003	0.997	0.000
Q61.4 Renal dysplasia	0.003	0.997	0.000
Q61.1 Polycystic kidney, infantile type	0.003	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.003	0.997	0.000
Q33 Congenital malformations of lung	0.003	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.997	0.000
Q31 Congenital malformations of larynx	0.003	0.997	0.000
Q30 Congenital malformations of nose	0.003	0.997	0.000
Q37 Cleft palate with cleft lip	0.003	0.997	0.000
Q36 Cleft lip	0.003	0.997	0.000
Q35 Cleft palate	0.003	0.997	0.000
Q89 Other congenital malformations, not elsewhere classified	0.003	0.997	0.000
Q21.8 Other congenital malformations of cardiac septa	0.003	0.997	0.000
Q21.4 Aortopulmonary septal defect	0.003	0.997	0.000
Q21.3 Tetralogy of Fallot	0.003	0.997	0.000
Q21.2 Atrioventricular septal defect	0.003	0.997	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.003	0.997	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.003	0.997	0.000
Q51.6 Embryonic cyst of cervix	0.003	0.997	0.000
Q51.5 Agenesis and aplasia of cervix	0.003	0.997	0.000
Q51.4 Unicornate uterus	0.003	0.997	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.003	0.997	0.000
Q51.0 Agenesis and aplasia of uterus	0.003	0.997	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.003	0.997	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.003	0.997	0.000
Q74.3 Arthrogryposis multiplex congenita	0.003	0.997	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.003	0.997	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.003	0.997	0.000
Q40.2 Other specified congenital malformations of stomach	0.003	0.997	0.000
Q85.1 Tuberous sclerosis	0.003	0.997	0.000
Y42.7 Androgens and anabolic congeners	0.003	0.997	0.000
Z64.4 Discord with counsellors	0.003	0.997	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.003	0.997	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.003	0.997	0.000
Z64.1 Problems related to multiparity	0.003	0.997	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.003	0.997	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.003	0.997	0.000
Q76.8 Other congenital malformations of bony thorax	0.003	0.997	0.000
Q76.7 Congenital malformation of sternum	0.003	0.997	0.000
Q76.6 Other congenital malformations of ribs	0.003	0.997	0.000
Q76.5 Cervical rib	0.003	0.997	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.003	0.997	0.000
Q76.2 Congenital spondylolisthesis	0.003	0.997	0.000
Q76.1 Klippel-Feil syndrome	0.003	0.997	0.000
Q87.4 Marfan's syndrome	0.003	0.997	0.000
Q04.6 Congenital cerebral cysts	0.003	0.997	0.000
Q21.1 Atrial septal defect	0.003	0.997	0.000
Q82.9 Congenital malformation of skin, unspecified	0.003	0.997	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.003	0.997	0.000
Q82.3 Incontinentia pigmenti	0.003	0.997	0.000
Q82.2 Mastocytosis	0.003	0.997	0.000
Q82.1 Xeroderma pigmentosum	0.003	0.997	0.000
Q82.0 Hereditary lymphoedema	0.003	0.997	0.000
Q67.6 Pectus excavatum	0.003	0.997	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.003	0.997	0.000
Q78.8 Other specified osteochondrodysplasias	0.003	0.997	0.000
Q78.6 Multiple congenital exostoses	0.003	0.997	0.000
Q78.5 Metaphyseal dysplasia	0.003	0.997	0.000
Q78.4 Enchondromatosis	0.003	0.997	0.000
Q78.3 Progressive diaphyseal dysplasia	0.003	0.997	0.000
Q78.2 Osteopetrosis	0.003	0.997	0.000
Q78.1 Polyostotic fibrous dysplasia	0.003	0.997	0.000
Y46.6 Other and unspecified antiepileptics	0.003	0.997	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.003	0.997	0.000
N73 Other female pelvic inflammatory diseases	0.003	0.997	0.000
Q07 Other congenital malformations of nervous system	0.003	0.997	0.000
Q51.3 Bicornate uterus	0.003	0.997	0.000
Q05 Spina bifida	0.003	0.997	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.003	0.997	0.000
Q64.8 Other specified congenital malformations of urinary system	0.003	0.997	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.003	0.997	0.000
Q64.6 Congenital diverticulum of bladder	0.003	0.997	0.000
Q64.5 Congenital absence of bladder and urethra	0.003	0.997	0.000
Q64.4 Malformation of urachus	0.003	0.997	0.000
Q64.2 Congenital posterior urethral valves	0.003	0.997	0.000
Q64.1 Exstrophy of urinary bladder	0.003	0.997	0.000
Q64.0 Epispadias	0.003	0.997	0.000
Y42.1 Thyroid hormones and substitutes	0.003	0.997	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.003	0.997	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.003	0.997	0.000
Q23.0 Congenital stenosis of aortic valve	0.003	0.997	0.000
Q67.8 Other congenital deformities of chest	0.003	0.997	0.000
Q67.7 Pectus carinatum	0.003	0.997	0.000
Q67.5 Congenital deformity of spine	0.003	0.997	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.003	0.997	0.000
Q67.3 Plagiocephaly	0.003	0.997	0.000
Q67.2 Dolichocephaly	0.003	0.997	0.000
Q67.1 Compression facies	0.003	0.997	0.000
Q67.0 Facial asymmetry	0.003	0.997	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.003	0.997	0.000
Y42.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
Y42.4 Oral contraceptives	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations