TreeWAS – Variant ID: rs6748734

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M81.99 Osteoporosis, unspecified (Site unspecified)	0.093	0.907	0.000
M81.9 Osteoporosis, unspecified	0.074	0.926	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.072	0.928	0.000
G56.0 Carpal tunnel syndrome	0.000	0.936	0.064
C83.3 Large cell (diffuse)	0.000	0.940	0.060
M81.96 Osteoporosis, unspecified (Lower leg)	0.059	0.940	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.942	0.058
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.057	0.942	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.053	0.947	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.947	0.053
M81.93 Osteoporosis, unspecified (Forearm)	0.053	0.947	0.000
C92.0 Acute myeloid leukaemia	0.000	0.949	0.051
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.949	0.051
C92 Myeloid leukaemia	0.000	0.950	0.050
M81.94 Osteoporosis, unspecified (Hand)	0.049	0.951	0.000
C83.7 Burkitt's tumour	0.000	0.952	0.048
M81.91 Osteoporosis, unspecified (Shoulder region)	0.047	0.953	0.000
M81.98 Osteoporosis, unspecified (Other)	0.046	0.954	0.000
C95 Leukaemia of unspecified cell type	0.000	0.956	0.044
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.957	0.043
C83.6 Undifferentiated (diffuse)	0.000	0.958	0.042
C83.4 Immunoblastic (diffuse)	0.000	0.958	0.042
C83.2 Mixed small and large cell (diffuse)	0.000	0.958	0.042
C83.0 Small cell (diffuse)	0.000	0.958	0.042
C83.1 Small cleaved cell (diffuse)	0.000	0.958	0.042
C86 Other specified types of T/NK-cell lymphoma	0.000	0.958	0.042
C92.5 Acute myelomonocytic leukaemia	0.000	0.959	0.041
C92.9 Myeloid leukaemia, unspecified	0.000	0.960	0.040
C81 Hodgkin's disease	0.000	0.961	0.039
C88 Malignant immunoproliferative diseases	0.000	0.961	0.039
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.961	0.039
C95.9 Leukaemia, unspecified	0.000	0.962	0.038
C83.5 Lymphoblastic (diffuse)	0.000	0.962	0.038
C94 Other leukaemias of specified cell type	0.000	0.962	0.038
M81.90 Osteoporosis, unspecified (Multiple sites)	0.037	0.963	0.000
C92.2 Subacute myeloid leukaemia	0.000	0.963	0.037
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.963	0.036
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.964	0.036
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.964	0.036
C92.3 Myeloid sarcoma	0.000	0.964	0.036
C95.1 Chronic leukaemia of unspecified cell type	0.000	0.964	0.036
C86.5 Angioimmunoblastic T-cell lymphoma	0.000	0.965	0.035
C92.7 Other myeloid leukaemia	0.000	0.965	0.035
M81 Osteoporosis without pathological fracture	0.034	0.966	0.000
C92.4 Acute promyelocytic leukaemia	0.000	0.966	0.034
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.966	0.034
C93 Monocytic leukaemia	0.000	0.966	0.033
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.967	0.033
C81.0 Lymphocytic predominance	0.000	0.967	0.033
C95.7 Other leukaemia of unspecified cell type	0.000	0.968	0.032
C95.2 Subacute leukaemia of unspecified cell type	0.000	0.968	0.032
C84.4 Peripheral T-cell lymphoma	0.000	0.968	0.032
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.969	0.031
C81.2 Mixed cellularity	0.000	0.969	0.031
C95.0 Acute leukaemia of unspecified cell type	0.000	0.970	0.030
C91 Lymphoid leukaemia	0.000	0.970	0.030
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.000	0.970	0.030
C86.4 Blastic NK-cell lymphoma	0.000	0.970	0.030
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.000	0.970	0.030
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.000	0.970	0.030
C86.1 Hepatosplenic T-cell lymphoma	0.000	0.970	0.030
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.000	0.970	0.030
C81.7 Other Hodgkin's disease	0.000	0.970	0.030
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.000	0.971	0.028
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.972	0.028
C81.3 Lymphocytic depletion	0.000	0.972	0.028
C84.5 Other and unspecified T-cell lymphomas	0.000	0.972	0.028
C88.9 Malignant immunoproliferative disease, unspecified	0.000	0.972	0.028
C88.7 Other malignant immunoproliferative diseases	0.000	0.972	0.028
C88.3 Immunoproliferative small intestinal disease	0.000	0.972	0.028
C88.2 Gamma heavy chain disease	0.000	0.972	0.028
C88.1 Alpha heavy chain disease	0.000	0.972	0.028
C84.9 Mature T/NK-cell lymphoma, unspecified	0.000	0.972	0.028
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.000	0.972	0.028
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.000	0.972	0.028
C84.3 Lymphoepithelioid lymphoma	0.000	0.972	0.028
C84.2 T-zone lymphoma	0.000	0.972	0.028
C84.1 Sezary's diease	0.000	0.972	0.028
C84.0 Mycosis fungoides	0.000	0.972	0.028
C85.1 B-cell lymphoma, unspecified	0.000	0.972	0.028
C94.7 Other specified leukaemias	0.000	0.973	0.027
C94.5 Acute myelofibrosis	0.000	0.973	0.027
C94.4 Acute panmyelosis	0.000	0.973	0.027
C94.3 Mast cell leukaemia	0.000	0.973	0.027
C94.2 Acute megakaryoblastic leukaemia	0.000	0.973	0.027
C94.1 Chronic erythraemia	0.000	0.973	0.027
C94.0 Acute erythraemia and erythroleukaemia	0.000	0.973	0.027
C81.1 Nodular sclerosis	0.000	0.973	0.027
M81.8 Other osteoporosis	0.027	0.973	0.000
C91.4 Hairy-cell leukaemia	0.000	0.973	0.027
M81.1 Postoophorectomy osteoporosis	0.027	0.973	0.000
N81.2 Incomplete uterovaginal prolapse	0.027	0.973	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.973	0.026
C96.8 Histiocytic sarcoma	0.000	0.973	0.026
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.973	0.026
C96.6 Unifocal Langerhans-cell histiocytosis	0.000	0.973	0.026
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.000	0.973	0.026
C96.4 Sarcoma of dendritic cells (accessory cells)	0.000	0.973	0.026
C96.3 True histiocytic lymphoma	0.000	0.973	0.026
C96.2 Malignant mast cell tumour	0.000	0.973	0.026
C96.1 Malignant histiocytosis	0.000	0.973	0.026
C96.0 Letterer-Siwe disease	0.000	0.973	0.026
C82.3 Follicular lymphoma grade IIIa	0.000	0.975	0.025
C92.1 Chronic myeloid leukaemia	0.000	0.975	0.025
C84.8 Cutaneous T-cell lymphoma, unspecified	0.000	0.975	0.025
M81.6 Localised osteoporosis [Lequesne]	0.025	0.975	0.000
M81.5 Idiopathic osteoporosis	0.025	0.975	0.000
C93.9 Monocytic leukaemia, unspecified	0.000	0.976	0.024
C93.7 Other monocytic leukaemia	0.000	0.976	0.024
C93.3 Juvenile myelomonocytic leukaemia	0.000	0.976	0.024
C93.2 Subacute monocytic leukaemia	0.000	0.976	0.024
C93.0 Acute monocytic leukaemia	0.000	0.976	0.024
C85.0 Lymphosarcoma	0.000	0.976	0.024
M81.0 Postmenopausal osteoporosis	0.023	0.976	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.976	0.023
M81.4 Drug-induced osteoporosis	0.023	0.977	0.000
C82.0 Small cleaved cell, follicular	0.000	0.977	0.023
G56 Mononeuropathies of upper limb	0.000	0.977	0.023
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.977	0.023
C82.4 Follicular lymphoma grade IIIb	0.000	0.977	0.023
C82.6 Cutaneous follicle centre lymphoma	0.000	0.977	0.023
C82.5 Diffuse follicle centre lymphoma	0.000	0.977	0.023
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.977	0.023
M81.80 Other osteoporosis (Multiple sites)	0.022	0.978	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.978	0.022
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.978	0.022
C91.7 Other lymphoid leukaemia	0.000	0.978	0.022
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.978	0.022
C91.3 Prolymphocytic leukaemia	0.000	0.978	0.022
C91.2 Subacute lymphocytic leukaemia	0.000	0.978	0.022
M81.2 Osteoporosis of disuse	0.021	0.978	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.000	0.978	0.021
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.021	0.978	0.000
C93.1 Chronic monocytic leukaemia	0.000	0.979	0.021
M81.3 Postsurgical malabsorption osteoporosis	0.021	0.979	0.000
C91.9 Lymphoid leukaemia, unspecified	0.000	0.979	0.021
C91.0 Acute lymphoblastic leukaemia	0.000	0.979	0.021
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.979	0.021
C82.2 Large cell, follicular	0.000	0.979	0.021
Y43.3 Other antineoplastic drugs	0.000	0.979	0.021
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.979	0.021
M81.49 Drug-induced osteoporosis (Site unspecified)	0.020	0.980	0.000
G56.8 Other mononeuropathies of upper limb	0.000	0.980	0.020
M81.89 Other osteoporosis (Site unspecified)	0.020	0.980	0.000
M81.88 Other osteoporosis (Other)	0.020	0.980	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.020	0.980	0.000
M81.86 Other osteoporosis (Lower leg)	0.020	0.980	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.020	0.980	0.000
M81.84 Other osteoporosis (Hand)	0.020	0.980	0.000
M81.83 Other osteoporosis (Forearm)	0.020	0.980	0.000
M81.82 Other osteoporosis (Upper arm)	0.020	0.980	0.000
M81.81 Other osteoporosis (Shoulder region)	0.020	0.980	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.019	0.981	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.019	0.981	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.019	0.981	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.019	0.981	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.019	0.981	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.019	0.981	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.019	0.981	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.019	0.981	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.019	0.981	0.000
C81.9 Hodgkin's disease, unspecified	0.000	0.981	0.019
Z51.1 Chemotherapy session for neoplasm	0.000	0.981	0.019
C91.5 Adult T-cell leukaemia	0.000	0.981	0.019
M81.59 Idiopathic osteoporosis (Site unspecified)	0.018	0.982	0.000
M81.58 Idiopathic osteoporosis (Other)	0.018	0.982	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.018	0.982	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.018	0.982	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.018	0.982	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.018	0.982	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.018	0.982	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.018	0.982	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.018	0.982	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.018	0.982	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.018	0.982	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.018	0.982	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.018	0.982	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.018	0.982	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.018	0.982	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.018	0.982	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.018	0.982	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.018	0.982	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.018	0.982	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.018	0.982	0.000
G56.9 Mononeuropathy of upper limb, unspecified	0.000	0.982	0.018
C90.1 Plasma cell leukaemia	0.000	0.983	0.017
M81.08 Postmenopausal osteoporosis (Other)	0.017	0.983	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.017	0.983	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.017	0.983	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.017	0.983	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.017	0.983	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.017	0.983	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.017	0.983	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.017	0.983	0.000
M81.48 Drug-induced osteoporosis (Other)	0.017	0.983	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.017	0.983	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.017	0.983	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.017	0.983	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.017	0.983	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.017	0.983	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.017	0.983	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.017	0.983	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.017	0.983	0.000
C90.3 Solitary plasmacytoma	0.000	0.984	0.016
G56.3 Lesion of radial nerve	0.000	0.984	0.016
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.984	0.016
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.016	0.984	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.984	0.016
M81.29 Osteoporosis of disuse (Site unspecified)	0.016	0.984	0.000
M81.28 Osteoporosis of disuse (Other)	0.016	0.984	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.016	0.984	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.016	0.984	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.016	0.984	0.000
M81.24 Osteoporosis of disuse (Hand)	0.016	0.984	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.016	0.984	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.016	0.984	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.016	0.984	0.000
G56.4 Causalgia	0.000	0.984	0.016
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.984	0.015
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.015	0.984	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.015	0.984	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.015	0.984	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.015	0.984	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.015	0.984	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.015	0.984	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.015	0.984	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.015	0.984	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.015	0.984	0.000
C90.2 Plasmacytoma, extramedullary	0.000	0.985	0.015
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.985	0.015
G56.1 Other lesions of median nerve	0.000	0.985	0.015
G56.2 Lesion of ulnar nerve	0.000	0.985	0.015
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.986	0.014
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.986	0.014
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.986	0.014
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.987	0.013
T43.2 Other and unspecified antidepressants	0.000	0.987	0.013
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.987	0.013
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.987	0.013
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.987	0.013
M80-M85 Disorders of bone density and structure	0.013	0.987	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.987	0.013
M81.20 Osteoporosis of disuse (Multiple sites)	0.012	0.987	0.000
T42.4 Benzodiazepines	0.000	0.988	0.012
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.012	0.988	0.001
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.988	0.012
M85 Other disorders of bone density and structure	0.012	0.988	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.988	0.012
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.988	0.012
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.988	0.012
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.989	0.011
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.989	0.011
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.989	0.011
T43.9 Psychotropic drug, unspecified	0.000	0.989	0.011
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.989	0.010
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.989	0.010
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.989	0.010
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.990	0.010
T50.7 Analeptics and opioid receptor antagonists	0.000	0.990	0.010
T50.5 Appetite depressants	0.000	0.990	0.010
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.990	0.010
T50.0 Mineralocorticoids and their antagonists	0.000	0.990	0.010
T42.0 Hydantoin derivatives	0.000	0.990	0.010
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.990	0.010
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.990	0.010
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.990	0.010
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.990	0.010
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.990	0.010
C91.1 Chronic lymphocytic leukaemia	0.000	0.990	0.010
T36 Poisoning by systemic antibiotics	0.000	0.990	0.010
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.990	0.010
T42.2 Succinimides and oxazolidinediones	0.000	0.990	0.010
T50.8 Diagnostic agents	0.000	0.990	0.010
M85.6 Other cyst of bone	0.010	0.990	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.990	0.010
T42.1 Iminostilbenes	0.000	0.990	0.010
M81.40 Drug-induced osteoporosis (Multiple sites)	0.010	0.990	0.000
M85.2 Hyperostosis of skull	0.010	0.990	0.000
T50.1 Loop [high-ceiling] diuretics	0.000	0.990	0.010
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.990	0.010
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.990	0.010
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.990	0.010
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.990	0.010
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.990	0.010
T44.0 Anticholinesterase agents	0.000	0.990	0.010
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.990	0.010
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.990	0.009
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.990	0.009
T46.7 Peripheral vasodilators	0.000	0.990	0.009
Y43 Primarily systemic agents	0.000	0.990	0.010
M85.9 Disorder of bone density and structure, unspecified	0.009	0.991	0.000
T46.1 Calcium-channel blockers	0.000	0.991	0.009
M80 Osteoporosis with pathological fracture	0.009	0.991	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.991	0.009
M83 Adult osteomalacia	0.009	0.991	0.000
M85.8 Other specified disorders of bone density and structure	0.009	0.991	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.991	0.009
C90.0 Multiple myeloma	0.000	0.991	0.009
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.991	0.009
T42.3 Barbiturates	0.000	0.991	0.009
M85.0 Fibrous dysplasia (monostotic)	0.009	0.991	0.000
Y43.4 Immunosuppressive agents	0.000	0.991	0.009
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.991	0.009
M85.65 Other cyst of bone (Pelvic region and thigh)	0.009	0.991	0.000
M85.5 Aneurysmal bone cyst	0.009	0.991	0.000
M85.3 Osteitis condensans	0.009	0.991	0.000
M85.1 Skeletal fluorosis	0.009	0.991	0.000
M82 Osteoporosis in diseases classified elsewhere	0.009	0.991	0.000
T50.4 Drugs affecting uric acid metabolism	0.000	0.992	0.008
M85.67 Other cyst of bone (Ankle and foot)	0.008	0.992	0.000
T49.9 Topical agent, unspecified	0.000	0.992	0.008
T49.8 Other topical agents	0.000	0.992	0.008
T49.7 Dental drugs, topically applied	0.000	0.992	0.008
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.992	0.008
T49.5 Ophthalmological drugs and preparations	0.000	0.992	0.008
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.992	0.008
T49.3 Emollients, demulcents and protectants	0.000	0.992	0.008
T49.2 Local astringents and local detergents	0.000	0.992	0.008
T49.1 Antipruritics	0.000	0.992	0.008
J02.9 Acute pharyngitis, unspecified	0.000	0.992	0.008
Z80.3 Family history of malignant neoplasm of breast	0.000	0.992	0.008
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.992	0.008
M85.22 Hyperostosis of skull-Upper arm	0.008	0.992	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.008	0.992	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.008	0.992	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.992	0.008
T48.4 Expectorants	0.000	0.992	0.008
T48.3 Antitussives	0.000	0.992	0.008
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.992	0.008
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.992	0.008
T48.0 Oxytocic drugs	0.000	0.992	0.008
M85.4 Solitary bone cyst	0.008	0.992	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.992	0.008
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.992	0.008
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.992	0.008
T37.5 Antiviral drugs	0.000	0.992	0.008
T37.4 Anthelminthics	0.000	0.992	0.008
T37.3 Other antiprotozoal drugs	0.000	0.992	0.008
T37.1 Antimycobacterial drugs	0.000	0.992	0.008
T37.0 Sulphonamides	0.000	0.992	0.008
M85.20 Hyperostosis of skull-Mult sites	0.008	0.992	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.992	0.008
M85.83 Other specified disorders of bone density and structure (Forearm)	0.008	0.992	0.000
T36.4 Tetracyclines	0.000	0.992	0.008
T41.5 Therapeutic gases	0.000	0.992	0.007
T41.4 Anaesthetic, unspecified	0.000	0.992	0.007
T41.3 Local anaesthetics	0.000	0.992	0.007
T41.2 Other and unspecified general anaesthetics	0.000	0.992	0.007
T41.1 Intravenous anaesthetics	0.000	0.992	0.007
T41.0 Inhaled anaesthetics	0.000	0.992	0.007
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.008	0.992	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.007	0.992	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.992	0.007
T36.0 Penicillins	0.000	0.992	0.007
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.008	0.992	0.000
T48.5 Anti-common-cold drugs	0.000	0.992	0.007
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.007	0.992	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.992	0.007
T36.8 Other systemic antibiotics	0.000	0.992	0.007
T36.7 Antifungal antibiotics, systemically used	0.000	0.992	0.007
T36.6 Rifamycins	0.000	0.992	0.007
T36.5 Aminoglycosides	0.000	0.992	0.007
T36.2 Chloramphenicol group	0.000	0.992	0.007
M85.68 Other cyst of bone (Other)	0.007	0.993	0.000
M85.69 Other cyst of bone (Site unspecified)	0.007	0.993	0.000
M85.63 Other cyst of bone (Forearm)	0.007	0.993	0.000
M85.62 Other cyst of bone (Upper arm)	0.007	0.993	0.000
M85.61 Other cyst of bone (Shoulder region)	0.007	0.993	0.000
M85.60 Other cyst of bone (Multiple sites)	0.007	0.993	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.993	0.007
M85.29 Hyperostosis of skull-Site unspec	0.007	0.993	0.000
M85.28 Hyperostosis of skull-Other	0.007	0.993	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.007	0.993	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.007	0.993	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.007	0.993	0.000
M85.24 Hyperostosis of skull-Hand	0.007	0.993	0.000
M85.23 Hyperostosis of skull-Forearm	0.007	0.993	0.000
M85.21 Hyperostosis of skull-Shldr region	0.007	0.993	0.000
M80.8 Other osteoporosis with pathological fracture	0.007	0.993	0.000
M43.1 Spondylolisthesis	0.007	0.993	0.000
M83.8 Other adult osteomalacia	0.007	0.993	0.000
M43 Other deforming dorsopathies	0.007	0.993	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.007	0.993	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.993	0.007
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.007	0.993	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.007	0.993	0.000
Y43.2 Antineoplastic natural products	0.000	0.993	0.007
Y43.9 Primarily systemic agent, unspecified	0.000	0.993	0.007
Y43.8 Other primarily systemic agents, not elsewhere classified	0.000	0.993	0.007
Y43.6 Enzymes, not elsewhere classified	0.000	0.993	0.007
Y43.5 Acidifying and alkalising agents	0.000	0.993	0.007
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.007	0.993	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.007	0.993	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.007	0.993	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.007	0.993	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.007	0.993	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.007	0.993	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.007	0.993	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.007	0.993	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.007	0.993	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.007	0.993	0.000
M83.3 Adult osteomalacia due to malnutrition	0.007	0.993	0.000
M83.9 Adult osteomalacia, unspecified	0.007	0.993	0.000
M83.5 Other drug-induced osteomalacia in adults	0.007	0.993	0.000
M83.4 Aluminum bone disease	0.007	0.993	0.000
M83.2 Adult osteomalacia due to malabsorption	0.007	0.993	0.000
M83.0 Puerperal osteomalacia	0.007	0.993	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.007	0.993	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.007	0.993	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.007	0.993	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.007	0.993	0.000
T36.3 Macrolides	0.000	0.993	0.007
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.007	0.993	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.007	0.993	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.007	0.993	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.007	0.993	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.007	0.993	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.007	0.993	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.007	0.993	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.007	0.993	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.007	0.993	0.000
M85.66 Other cyst of bone (Lower leg)	0.007	0.993	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.007	0.993	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.007	0.993	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.006	0.993	0.000
M85.18 Skeletal fluorosis (Other)	0.006	0.993	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.006	0.993	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.006	0.993	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.006	0.993	0.000
M85.14 Skeletal fluorosis (Hand)	0.006	0.993	0.000
M85.13 Skeletal fluorosis (Forearm)	0.006	0.993	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.006	0.993	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.006	0.993	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.006	0.993	0.000
M85.39 Osteitis condensans (Site unspecified)	0.006	0.993	0.000
M85.38 Osteitis condensans (Other)	0.006	0.993	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.006	0.993	0.000
M85.36 Osteitis condensans (Lower leg)	0.006	0.993	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.006	0.993	0.000
M85.34 Osteitis condensans (Hand)	0.006	0.993	0.000
M85.33 Osteitis condensans (Forearm)	0.006	0.993	0.000
M85.32 Osteitis condensans (Upper arm)	0.006	0.993	0.000
M85.31 Osteitis condensans (Shoulder region)	0.006	0.993	0.000
M85.30 Osteitis condensans (Multiple sites)	0.006	0.993	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.006	0.993	0.000
M85.58 Aneurysmal bone cyst (Other)	0.006	0.993	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.006	0.993	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.006	0.993	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.006	0.993	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.006	0.993	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.006	0.993	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.006	0.993	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.006	0.993	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.006	0.993	0.000
M85.64 Other cyst of bone (Hand)	0.006	0.993	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.006	0.993	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.006	0.993	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.006	0.993	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.006	0.993	0.000
M43.0 Spondylolysis	0.007	0.993	0.000
M83.1 Senile osteomalacia	0.006	0.994	0.000
M25.8 Other specified joint disorders	0.006	0.994	0.000
J02 Acute pharyngitis	0.000	0.994	0.006
M43.6 Torticollis	0.006	0.994	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.006	0.994	0.000
M25.84 Other specified joint disorders (Hand)	0.006	0.994	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.006	0.994	0.000
Y43.1 Antineoplastic antimetabolites	0.000	0.994	0.006
T47.0 Histamine H(2)-receptor antagonists	0.000	0.994	0.006
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.006	0.994	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.006	0.994	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.006	0.994	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.006	0.994	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.006	0.994	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.006	0.994	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.006	0.994	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.006	0.994	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.006	0.994	0.000
M40.2 Other and unspecified kyphosis	0.006	0.994	0.000
M85.46 Solitary bone cyst (Lower leg)	0.006	0.994	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.006	0.994	0.000
M85.48 Solitary bone cyst (Other)	0.006	0.994	0.000
M85.44 Solitary bone cyst (Hand)	0.006	0.994	0.000
M85.43 Solitary bone cyst (Forearm)	0.006	0.994	0.000
M85.42 Solitary bone cyst (Upper arm)	0.006	0.994	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.006	0.994	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.006	0.994	0.000
T47.6 Antidiarrhoeal drugs	0.000	0.994	0.006
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.994	0.006
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.994	0.006
T47.7 Emetics	0.000	0.994	0.006
T47.5 Digestants	0.000	0.994	0.006
T47.3 Saline and osmotic laxatives	0.000	0.994	0.006
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.006	0.994	0.000
J02.0 Streptococcal pharyngitis	0.000	0.994	0.006
M43.17 Spondylolisthesis (Lumbosacral region)	0.006	0.994	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.006	0.994	0.000
M40 Kyphosis and lordosis	0.006	0.994	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.006	0.994	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.006	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations