TreeWAS – Variant ID: rs680379

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.683	0.317
K80 Cholelithiasis	0.000	0.696	0.304
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.698	0.302
K80.8 Other cholelithiasis	0.000	0.724	0.276
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.741	0.259
K80.3 Calculus of bile duct with cholangitis	0.000	0.782	0.218
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.826	0.174
K86 Other diseases of pancreas	0.000	0.828	0.172
K86.3 Pseudocyst of pancreas	0.000	0.830	0.170
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.000	0.843	0.156
K86.8 Other specified diseases of pancreas	0.000	0.847	0.153
K85 Acute pancreatitis	0.000	0.855	0.145
K86.1 Other chronic pancreatitis	0.000	0.865	0.135
K85.1 Biliary acute pancreatitis	0.000	0.868	0.132
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.875	0.125
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.876	0.124
K85.2 Alcohol-induced acute pancreatitis	0.000	0.884	0.116
K86.2 Cyst of pancreas	0.000	0.891	0.109
K85.8 Other acute pancreatitis	0.000	0.893	0.107
K82 Other diseases of gallbladder	0.000	0.895	0.105
K85.3 Drug-induced acute pancreatitis	0.000	0.903	0.097
K85.0 Idiopathic acute pancreatitis	0.000	0.907	0.093
B07 Viral warts	0.000	0.908	0.092
K87.1 Disorders of pancreas in diseases classified elsewhere	0.000	0.910	0.090
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.000	0.910	0.090
K82.0 Obstruction of gallbladder	0.000	0.910	0.090
K82.2 Perforation of gallbladder	0.000	0.914	0.086
K80.4 Calculus of bile duct with cholecystitis	0.000	0.916	0.084
K86.9 Disease of pancreas, unspecified	0.000	0.917	0.083
K85.9 Acute pancreatitis, unspecified	0.000	0.920	0.080
K82.3 Fistula of gallbladder	0.000	0.922	0.078
K82.9 Disease of gallbladder, unspecified	0.000	0.929	0.071
K82.1 Hydrops of gallbladder	0.000	0.939	0.061
D68.9 Coagulation defect, unspecified	0.000	0.942	0.058
K82.4 Cholesterolosis of gallbladder	0.000	0.944	0.056
D68 Other coagulation defects	0.000	0.946	0.054
D68.6 Other Thrombophilia	0.000	0.947	0.053
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.000	0.953	0.047
K82.8 Other specified diseases of gallbladder	0.000	0.955	0.045
D68.2 Hereditary deficiency of other clotting factors	0.000	0.956	0.044
D68.5 Primary Thrombophilia	0.000	0.957	0.043
D68.8 Other specified coagulation defects	0.000	0.957	0.043
K81 Cholecystitis	0.000	0.958	0.042
B02 Zoster [herpes zoster]	0.000	0.959	0.041
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.959	0.041
D69 Purpura and other haemorrhagic conditions	0.000	0.961	0.039
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.962	0.038
M13.96 Arthritis, unspecified (Lower leg)	0.000	0.962	0.038
K81.8 Other cholecystitis	0.000	0.962	0.038
B02.3 Zoster ocular disease	0.000	0.964	0.035
D68.0 Von Willebrand's disease	0.000	0.965	0.035
D68.4 Acquired coagulation factor deficiency	0.000	0.965	0.035
B02.2 Zoster with other nervous system involvement	0.000	0.966	0.034
B01 Varicella [chickenpox]	0.000	0.966	0.034
D69.4 Other primary thrombocytopenia	0.000	0.966	0.034
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.000	0.966	0.034
B06 Rubella [German measles]	0.000	0.966	0.033
B05 Measles	0.000	0.966	0.033
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.000	0.966	0.033
B04 Monkeypox	0.000	0.966	0.033
B03 Smallpox	0.000	0.966	0.033
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.967	0.033
D69.9 Haemorrhagic condition, unspecified	0.000	0.968	0.032
B02.9 Zoster without complication	0.000	0.968	0.032
D66 Hereditary factor VIII deficiency	0.000	0.969	0.031
D69.8 Other specified haemorrhagic conditions	0.000	0.969	0.031
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.969	0.031
R07.0 Pain in throat	0.000	0.969	0.031
B02.1 Zoster meningitis	0.000	0.970	0.030
D68.1 Hereditary factor XI deficiency	0.000	0.970	0.030
B02.7 Disseminated zoster	0.000	0.970	0.030
B02.0 Zoster encephalitis	0.000	0.970	0.030
D69.2 Other nonthrombocytopenic purpura	0.000	0.971	0.029
K83 Other diseases of biliary tract	0.000	0.971	0.029
D67 Hereditary factor IX deficiency	0.000	0.972	0.028
B01.8 Varicella with other complications	0.000	0.972	0.028
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.973	0.027
B02.8 Zoster with other complications	0.000	0.973	0.026
D69.6 Thrombocytopenia, unspecified	0.000	0.974	0.026
B01.9 Varicella without complications	0.000	0.974	0.026
D69.1 Qualitative platelet defects	0.000	0.974	0.026
B01.1 Varicella encephalitis	0.000	0.975	0.025
B08.1 Molluscum contagiosum	0.000	0.975	0.025
B08.8 Other specified viral infections characterised by skin and mucous membrane lesions	0.000	0.975	0.024
B08.5 Enteroviral vesicular pharyngitis	0.000	0.975	0.024
B08.4 Enteroviral vesicular stomatitis with exanthem	0.000	0.975	0.024
B08.3 Erythema infectiosum [fifth disease]	0.000	0.975	0.024
B08.2 Exanthema subitum [sixth disease]	0.000	0.975	0.024
B08.0 Other orthopoxvirus infections	0.000	0.975	0.024
B05.9 Measles without complication	0.000	0.976	0.024
B05.8 Measles with other complications	0.000	0.976	0.024
B05.4 Measles with intestinal complications	0.000	0.976	0.024
B05.3 Measles complicated by otitis media	0.000	0.976	0.024
B05.2 Measles complicated by pneumonia	0.000	0.976	0.024
B05.1 Measles complicated by meningitis	0.000	0.976	0.024
B05.0 Measles complicated by encephalitis	0.000	0.976	0.024
B06.9 Rubella without complication	0.000	0.976	0.024
B06.8 Rubella with other complications	0.000	0.976	0.024
B06.0 Rubella with neurological complications	0.000	0.976	0.024
B01.0 Varicella meningitis	0.000	0.976	0.024
D69.0 Allergic purpura	0.000	0.977	0.023
K83.0 Cholangitis	0.000	0.977	0.023
K83.5 Biliary cyst	0.000	0.978	0.022
B00 Herpesviral [herpes simplex] infections	0.000	0.978	0.022
B01.2 Varicella pneumonia	0.000	0.979	0.021
D69.5 Secondary thrombocytopenia	0.000	0.979	0.021
K83.4 Spasm of sphincter of Oddi	0.000	0.980	0.020
K83.2 Perforation of bile duct	0.000	0.980	0.020
K81.9 Cholecystitis, unspecified	0.000	0.980	0.020
K83.3 Fistula of bile duct	0.000	0.983	0.017
B00.1 Herpesviral vesicular dermatitis	0.000	0.983	0.017
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.000	0.983	0.016
B00.4 Herpesviral encephalitis	0.000	0.984	0.016
B00.7 Disseminated herpesviral disease	0.000	0.984	0.016
B00.0 Eczema herpeticum	0.000	0.984	0.016
B00.5 Herpesviral ocular disease	0.000	0.985	0.015
K83.9 Disease of biliary tract, unspecified	0.000	0.985	0.015
B00.3 Herpesviral meningitis	0.000	0.986	0.014
B00.8 Other forms of herpesviral infection	0.000	0.986	0.013
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.986	0.014
D72.8 Other specified disorders of white blood cells	0.009	0.991	0.000
G51.0 Bell's palsy	0.009	0.991	0.000
I50.9 Heart failure, unspecified	0.009	0.991	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.009	0.991	0.000
B00.9 Herpesviral infection, unspecified	0.001	0.991	0.008
M13.91 Arthritis, unspecified (Shoulder region)	0.000	0.992	0.008
M13.9 Arthritis, unspecified	0.000	0.992	0.008
I60 Subarachnoid haemorrhage	0.008	0.992	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.000	0.993	0.007
I82.8 Embolism and thrombosis of other specified veins	0.000	0.993	0.007
I60.9 Subarachnoid haemorrhage, unspecified	0.007	0.993	0.000
K83.1 Obstruction of bile duct	0.000	0.993	0.007
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.993	0.007
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.007	0.993	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.007	0.993	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.007	0.993	0.000
M23.8 Other internal derangements of knee	0.000	0.993	0.006
M13.92 Arthritis, unspecified (Upper arm)	0.000	0.994	0.006
F30.0 Hypomania	0.000	0.994	0.006
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.006	0.994	0.000
D86.0 Sarcoidosis of lung	0.000	0.994	0.006
K83.8 Other specified diseases of biliary tract	0.000	0.994	0.006
M13.98 Arthritis, unspecified (Other)	0.000	0.994	0.006
I60.5 Subarachnoid haemorrhage from vertebral artery	0.006	0.994	0.000
F30.2 Mania with psychotic symptoms	0.000	0.994	0.006
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.000	0.994	0.006
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.005	0.994	0.000
D86 Sarcoidosis	0.000	0.995	0.005
F30 Manic episode	0.000	0.995	0.005
K81.0 Acute cholecystitis	0.000	0.995	0.005
R79.9 Abnormal finding of blood chemistry, unspecified	0.005	0.995	0.000
M13.93 Arthritis, unspecified (Forearm)	0.000	0.995	0.005
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.995	0.005
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.995	0.005
G51 Facial nerve disorders	0.005	0.995	0.000
I60.8 Other subarachnoid haemorrhage	0.005	0.995	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.995	0.005
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.995	0.005
D80-D89 Certain disorders involving the immune mechanism	0.000	0.995	0.005
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.995	0.005
D72 Other disorders of white blood cells	0.004	0.995	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.995	0.004
M79.64 Pain in limb (Hand)	0.000	0.995	0.005
D86.8 Sarcoidosis of other and combined sites	0.000	0.996	0.004
I82 Other venous embolism and thrombosis	0.000	0.996	0.004
F30.1 Mania without psychotic symptoms	0.000	0.996	0.004
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.996	0.004
G51.9 Disorder of facial nerve, unspecified	0.004	0.996	0.000
D86.3 Sarcoidosis of skin	0.000	0.996	0.004
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.996	0.004
D80 Immunodeficiency with predominantly antibody defects	0.000	0.996	0.004
D86.9 Sarcoidosis, unspecified	0.000	0.996	0.004
A63.0 Anogenital (venereal) warts	0.000	0.996	0.004
X59.2 School, other institution and public administrative area	0.004	0.996	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.004	0.996	0.000
Z48.9 Surgical follow-up care, unspecified	0.004	0.996	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.996	0.004
F30.8 Other manic episodes	0.000	0.996	0.004
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.996	0.004
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.996	0.004
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.996	0.004
G51.4 Facial myokymia	0.004	0.996	0.000
G51.2 Melkersson's syndrome	0.004	0.996	0.000
G51.1 Geniculate ganglionitis	0.004	0.996	0.000
K81.1 Chronic cholecystitis	0.000	0.996	0.004
G51.8 Other disorders of facial nerve	0.004	0.996	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.996	0.004
G51.3 Clonic hemifacial spasm	0.004	0.996	0.000
I82.2 Embolism and thrombosis of vena cava	0.000	0.996	0.004
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.004	0.996	0.000
F30.9 Manic episode, unspecified	0.000	0.996	0.004
D72.1 Eosinophilia	0.004	0.996	0.000
D81 Combined immunodeficiencies	0.000	0.996	0.003
M13.94 Arthritis, unspecified (Hand)	0.000	0.996	0.004
D72.9 Disorder of white blood cells, unspecified	0.003	0.996	0.000
D72.0 Genetic anomalies of leukocytes	0.003	0.996	0.000
D84 Other immunodeficiencies	0.000	0.996	0.003
E14.3 With ophthalmic complications	0.000	0.996	0.004
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.996	0.003
I82.0 Budd-Chiari syndrome	0.000	0.996	0.003
I82.3 Embolism and thrombosis of renal vein	0.000	0.997	0.003
D83 Common variable immunodeficiency	0.000	0.997	0.003
D82 Immunodeficiency associated with other major defects	0.000	0.997	0.003
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.997	0.003
D86.1 Sarcoidosis of lymph nodes	0.000	0.997	0.003
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.997	0.003
I82.1 Thrombophlebitis migrans	0.000	0.997	0.003
Z29.2 Other prophylactic chemotherapy	0.003	0.997	0.000
D84.1 Defects in the complement system	0.000	0.997	0.003
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.997	0.003
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.997	0.003
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.997	0.003
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.997	0.003
D55-D59 Haemolytic anaemias	0.000	0.997	0.003
Y45.1 Salicylates	0.003	0.997	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.997	0.003
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.003	0.997	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.000	0.997	0.003
K74.6 Other and unspecified cirrhosis of liver	0.000	0.997	0.003
A08.4 Viral intestinal infection, unspecified	0.000	0.997	0.003
D57 Sickle-cell disorders	0.000	0.997	0.003
M13 Other arthritis	0.000	0.997	0.003
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.997	0.003
D81.9 Combined immunodeficiency, unspecified	0.000	0.997	0.003
D81.8 Other combined immunodeficiencies	0.000	0.997	0.003
D81.7 Major histocompatibility complex class II deficiency	0.000	0.997	0.003
D81.6 Major histocompatibility complex class I deficiency	0.000	0.997	0.003
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.997	0.003
D81.4 Nezelof's syndrome	0.000	0.997	0.003
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.997	0.003
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.997	0.003
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.997	0.003
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.997	0.003
X59 Exposure to unspecified factor	0.003	0.997	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.997	0.003
D58 Other hereditary haemolytic anaemias	0.000	0.997	0.003
D83.8 Other common variable immunodeficiencies	0.000	0.997	0.003
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.997	0.003
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.997	0.003
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.997	0.003
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.997	0.003
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.997	0.003
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.997	0.003
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.997	0.003
D82.2 Immunodeficiency with short-limbed stature	0.000	0.997	0.003
D82.0 Wiskott-Aldrich syndrome	0.000	0.997	0.003
Z89.5 Acquired absence of leg at or below knee	0.003	0.997	0.000
O47.0 False labour before 37 completed weeks of gestation	0.003	0.997	0.000
D57.1 Sickle-cell anaemia without crisis	0.000	0.997	0.003
O47.1 False labour at or after 37 completed weeks of gestation	0.003	0.997	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
D58.2 Other haemoglobinopathies	0.000	0.997	0.003
D83.9 Common variable immunodeficiency, unspecified	0.000	0.997	0.002
D55 Anaemia due to enzyme disorders	0.000	0.997	0.002
X59.6 Industrial and construction area	0.003	0.997	0.000
D82.1 Di George's syndrome	0.000	0.997	0.002
K05.3 Chronic periodontitis	0.000	0.997	0.003
N80.8 Other endometriosis	0.000	0.997	0.003
H40.2 Primary angle-closure glaucoma	0.003	0.997	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.000	0.997	0.002
D84.9 Immunodeficiency, unspecified	0.000	0.997	0.002
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
D84.8 Other specified immunodeficiencies	0.000	0.998	0.002
X59.3 Sports and athletics area	0.002	0.998	0.000
D57.8 Other sickle-cell disorders	0.000	0.998	0.002
D57.3 Sickle-cell trait	0.000	0.998	0.002
D57.2 Double heterozygous sickling disorders	0.000	0.998	0.002
D57.0 Sickle-cell anaemia with crisis	0.000	0.998	0.002
Z48.8 Other specified surgical follow-up care	0.002	0.998	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.000	0.998	0.002
M13.1 Monoarthritis, not elsewhere classified	0.000	0.998	0.002
X59.9 Unspecified place	0.002	0.998	0.000
X59.8 Other specified place	0.002	0.998	0.000
X59.0 Home	0.002	0.998	0.000
X59.7 Farm	0.002	0.998	0.000
X59.5 Trade and service area	0.002	0.998	0.000
X59.1 Residential institution	0.002	0.998	0.000
D59 Acquired haemolytic anaemia	0.000	0.998	0.002
I50 Heart failure	0.002	0.998	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.001
D58.8 Other specified hereditary haemolytic anaemias	0.000	0.998	0.002
D58.1 Hereditary elliptocytosis	0.000	0.998	0.002
Z85.9 Personal history of malignant neoplasm, unspecified	0.002	0.998	0.000
J98.1 Pulmonary collapse	0.002	0.998	0.000
X59.4 Street and highway	0.002	0.998	0.000
M13.8 Other specified arthritis	0.000	0.998	0.002
N20.2 Calculus of kidney with calculus of ureter	0.000	0.998	0.002
T02.4 Fractures involving multiple regions of both upper limbs	0.002	0.998	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.998	0.002
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.998	0.002
D55.8 Other anaemias due to enzyme disorders	0.000	0.998	0.002
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.998	0.002
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.998	0.002
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.998	0.002
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.998	0.002
D56 Thalassaemia	0.000	0.998	0.002
C78.4 Secondary malignant neoplasm of small intestine	0.002	0.998	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.000	0.998	0.002
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.998	0.002
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.998	0.002
S62.51 Fracture of thumb (open)	0.000	0.998	0.002
D58.0 Hereditary spherocytosis	0.000	0.998	0.002
M13.0 Polyarthritis, unspecified	0.000	0.998	0.002
D89.3 Immune reconstitution syndrome	0.000	0.998	0.002
N97.9 Female infertility, unspecified	0.000	0.998	0.002
N13.8 Other obstructive and reflux uropathy	0.002	0.998	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.002	0.998	0.000
M13.19 Monoarthritis, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M13.18 Monoarthritis, not elsewhere classified (Other)	0.000	0.998	0.002
M13.17 Monoarthritis, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
M13.15 Monoarthritis, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
M13.14 Monoarthritis, not elsewhere classified (Hand)	0.000	0.998	0.002
M13.13 Monoarthritis, not elsewhere classified (Forearm)	0.000	0.998	0.002
M13.12 Monoarthritis, not elsewhere classified (Upper arm)	0.000	0.998	0.002
M13.11 Monoarthritis, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
M13.10 Monoarthritis, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
M13.86 Other specified arthritis (Lower leg)	0.000	0.998	0.002
X59.09 Exposure to unspecified factor causing fracture; Unspecified place;	0.002	0.998	0.000
X59.88 Exposure to unspecified factor; Other specified places ;While engaged in other specified activities	0.002	0.998	0.000
X59.99 Exposure to unspecified factor causing other and unspecified injury, Unspecified place	0.002	0.998	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.002	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.000	0.998	0.002
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.998	0.002
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.998	0.002
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.998	0.002
D59.3 Haemolytic-uraemic syndrome	0.000	0.998	0.002
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.998	0.002
D59.1 Other autoimmune haemolytic anaemias	0.000	0.998	0.002
K65.9 Peritonitis, unspecified	0.000	0.998	0.002
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.998	0.002
M13.16 Monoarthritis, not elsewhere classified (Lower leg)	0.000	0.998	0.002
M13.89 Other specified arthritis (Site unspecified)	0.000	0.998	0.002
M13.88 Other specified arthritis (Other)	0.000	0.998	0.002
M13.85 Other specified arthritis (Pelvic region and thigh)	0.000	0.998	0.002
M13.84 Other specified arthritis (Hand)	0.000	0.998	0.002
M13.83 Other specified arthritis (Forearm)	0.000	0.998	0.002
M13.82 Other specified arthritis (Upper arm)	0.000	0.998	0.002
M13.81 Other specified arthritis (Shoulder region)	0.000	0.998	0.002
A63.8 Other specified predominantly sexually transmitted diseases	0.000	0.998	0.002
Z48 Other surgical follow-up care	0.002	0.998	0.000
T02.41 Fractures involving multiple regions of both upper limbs (open)	0.002	0.998	0.000
O04.4 Incomplete, without complication	0.002	0.998	0.000
M13.87 Other specified arthritis (Ankle and foot)	0.000	0.998	0.002
D56.9 Thalassaemia, unspecified	0.000	0.998	0.001
D56.8 Other thalassaemias	0.000	0.998	0.001
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.000	0.998	0.001
D56.2 Delta-beta thalassaemia	0.000	0.998	0.001
D56.0 Alpha thalassaemia	0.000	0.998	0.001
D89.1 Cryoglobulinaemia	0.000	0.998	0.002
T46.1 Calcium-channel blockers	0.002	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.998	0.002
D61.9 Aplastic anaemia, unspecified	0.002	0.998	0.000
I27.9 Pulmonary heart disease, unspecified	0.002	0.998	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.998	0.002
M75.2 Bicipital tendinitis	0.000	0.998	0.002
O47.9 False labour, unspecified	0.000	0.998	0.002
M13.06 Polyarthritis, unspecified (Lower leg)	0.000	0.998	0.002
M13.04 Polyarthritis, unspecified (Hand)	0.000	0.998	0.002
C90.0 Multiple myeloma	0.002	0.998	0.000
M13.08 Polyarthritis, unspecified (Other)	0.000	0.998	0.002
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M13.03 Polyarthritis, unspecified (Forearm)	0.000	0.998	0.002
M13.02 Polyarthritis, unspecified (Upper arm)	0.000	0.998	0.002
M13.01 Polyarthritis, unspecified (Shoulder region)	0.000	0.998	0.002
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.998	0.002
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.001
A46 Erysipelas	0.000	0.998	0.002
B18.1 Chronic viral hepatitis B without delta-agent	0.002	0.998	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.998	0.002
O47 False labour	0.002	0.998	0.000
D56.1 Beta thalassaemia	0.000	0.998	0.001
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.998	0.002
M13.00 Polyarthritis, unspecified (Multiple sites)	0.000	0.998	0.002
I50.0 Congestive heart failure	0.002	0.998	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.998	0.002
M13.80 Other specified arthritis (Multiple sites)	0.000	0.998	0.001
I87.8 Other specified disorders of veins	0.002	0.998	0.000
O30.0 Twin pregnancy	0.000	0.998	0.002
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.998	0.002
D60-D64 Aplastic and other anaemias	0.000	0.998	0.001
B19.9 Unspecified viral hepatitis without coma	0.002	0.998	0.000
M17.1 Other primary gonarthrosis	0.000	0.998	0.002
D62 Acute posthaemorrhagic anaemia	0.000	0.998	0.002
I61 Intracerebral haemorrhage	0.000	0.998	0.002
B18.2 Chronic viral hepatitis C	0.002	0.998	0.000
E87.0 Hyperosmolality and hypernatraemia	0.000	0.998	0.002
D56.3 Thalassaemia trait	0.001	0.998	0.001
I31.3 Pericardial effusion (noninflammatory)	0.002	0.998	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.998	0.002
T51.9 Alcohol, unspecified	0.002	0.998	0.000
Z89.6 Acquired absence of leg above knee	0.002	0.998	0.000
I84.1 Internal haemorrhoids with other complications	0.002	0.998	0.000
S60.8 Other superficial injuries of wrist and hand	0.000	0.998	0.002
A50-A64 Infections with a predominantly sexual mode of transmission	0.000	0.998	0.001
N30.1 Interstitial cystitis (chronic)	0.000	0.998	0.002
B18 Chronic viral hepatitis	0.001	0.998	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.998	0.001
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.998	0.001
S02.10 Fracture of base of skull (closed)	0.000	0.998	0.001
H70.9 Mastoiditis, unspecified	0.000	0.998	0.001
N80.0 Endometriosis of uterus	0.000	0.998	0.002
I27.2 Other secondary pulmonary hypertension	0.001	0.999	0.000
B15.9 Hepatitis A without hepatic coma	0.001	0.999	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.000	0.999	0.001
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.999	0.001
N21.0 Calculus in bladder	0.000	0.999	0.001
D61 Other aplastic anaemias	0.001	0.999	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.000	0.999	0.001
Z00.6 Examination for normal comparison and control in clinical research programme	0.000	0.999	0.001
S82.2 Fracture of shaft of tibia	0.000	0.999	0.001
X78.0 Home	0.001	0.999	0.000
T02 Fractures involving multiple body regions	0.001	0.999	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.999	0.001
M17.3 Other posttraumatic gonarthrosis	0.000	0.999	0.001
R25.8 Other and unspecified abnormal involuntary movements	0.001	0.999	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.001	0.999	0.000
B19 Unspecified viral hepatitis	0.001	0.999	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.001	0.999	0.000
Z00.5 Examination of potential donor of organ and tissue	0.000	0.999	0.001
Z89 Acquired absence of limb	0.001	0.999	0.000
B18.8 Other chronic viral hepatitis	0.001	0.999	0.000
B18.0 Chronic viral hepatitis B with delta-agent	0.001	0.999	0.000
K91.4 Colostomy and enterostomy malfunction	0.000	0.999	0.001
N21.1 Calculus in urethra	0.000	0.999	0.001
Z46.7 Fitting and adjustment of orthopaedic device	0.000	0.999	0.001
A59 Trichomoniasis	0.000	0.999	0.001
A56 Other sexually transmitted chlamydial diseases	0.000	0.999	0.001
A54 Gonococcal infection	0.000	0.999	0.001
A53 Other and unspecified syphilis	0.000	0.999	0.001
A51 Early syphilis	0.000	0.999	0.001
A50 Congenital syphilis	0.000	0.999	0.001
A64 Unspecified sexually transmitted disease	0.000	0.999	0.001
A58 Granuloma inguinale	0.000	0.999	0.001
A57 Chancroid	0.000	0.999	0.001
A55 Chlamydial lymphogranuloma (venereum)	0.000	0.999	0.001
D60.8 Other acquired pure red cell aplasias	0.000	0.999	0.001
D60.1 Transient acquired pure red cell aplasia	0.000	0.999	0.001
D60.0 Chronic acquired pure red cell aplasia	0.000	0.999	0.001
G24.9 Dystonia, unspecified	0.001	0.999	0.000
Y45.2 Propionic acid derivatives	0.001	0.999	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.001	0.999	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.000	0.999	0.001
B15 Acute hepatitis A	0.001	0.999	0.000
D61.0 Constitutional aplastic anaemia	0.001	0.999	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.001	0.999	0.000
A52 Late syphilis	0.000	0.999	0.001
D61.8 Other specified aplastic anaemias	0.001	0.999	0.000
D61.3 Idiopathic aplastic anaemia	0.001	0.999	0.000
D61.2 Aplastic anaemia due to other external agents	0.001	0.999	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.999	0.001
T02.8 Fractures involving other combinations of body regions	0.001	0.999	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.001	0.999	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.999	0.001
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.999	0.001
J98.9 Respiratory disorder, unspecified	0.001	0.999	0.000
T02.9 Multiple fractures, unspecified	0.001	0.999	0.000
T02.7 Fractures involving thorax with lower back and pelvis with limb(s)	0.001	0.999	0.000
T02.6 Fractures involving multiple regions of upper limb(s) with lower limb(s)	0.001	0.999	0.000
T02.3 Fractures involving multiple regions of one lower limb	0.001	0.999	0.000
T02.2 Fractures involving multiple regions of one upper limb	0.001	0.999	0.000
T02.1 Fractures involving thorax with lower back and pelvis	0.001	0.999	0.000
T02.0 Fractures involving head with neck	0.001	0.999	0.000
A60 Anogenital herpesviral [herpes simplex] infections	0.000	0.999	0.001
B18.9 Chronic viral hepatitis, unspecified	0.001	0.999	0.000
B19.0 Unspecified viral hepatitis with coma	0.001	0.999	0.000
C78.7 Secondary malignant neoplasm of liver	0.001	0.999	0.000
A50.9 Congenital syphilis, unspecified	0.000	0.999	0.001
A50.7 Late congenital syphilis, unspecified	0.000	0.999	0.001
A50.6 Late congenital syphilis, latent	0.000	0.999	0.001
A50.5 Other late congenital syphilis, symptomatic	0.000	0.999	0.001
A50.4 Late congenital neurosyphilis [juvenile neurosyphilis]	0.000	0.999	0.001
A50.3 Late congenital syphilitic oculopathy	0.000	0.999	0.001
A50.2 Early congenital syphilis, unspecified	0.000	0.999	0.001
A50.1 Early congenital syphilis, latent	0.000	0.999	0.001
A50.0 Early congenital syphilis, symptomatic	0.000	0.999	0.001
A51.9 Early syphilis, unspecified	0.000	0.999	0.001
A51.5 Early syphilis, latent	0.000	0.999	0.001
A51.4 Other secondary syphilis	0.000	0.999	0.001
A51.3 Secondary syphilis of skin and mucous membranes	0.000	0.999	0.001
A51.2 Primary syphilis of other sites	0.000	0.999	0.001
A51.1 Primary anal syphilis	0.000	0.999	0.001
A51.0 Primary genital syphilis	0.000	0.999	0.001
A53.9 Syphilis, unspecified	0.000	0.999	0.001
A53.0 Latent syphilis, unspecified as early or late	0.000	0.999	0.001
A54.9 Gonococcal infection, unspecified	0.000	0.999	0.001
A54.8 Other gonococcal infections	0.000	0.999	0.001
A54.6 Gonococcal infection of anus and rectum	0.000	0.999	0.001
A54.5 Gonococcal pharyngitis	0.000	0.999	0.001
A54.4 Gonococcal infection of musculoskeletal system	0.000	0.999	0.001
A54.3 Gonococcal infection of eye	0.000	0.999	0.001
A54.2 Gonococcal pelviperitonitis and other gonococcal genito-urinary infections	0.000	0.999	0.001
A54.1 Gonococcal infection of lower genito-urinary tract with periurethral and accessory gland abscess	0.000	0.999	0.001
A54.0 Gonococcal infection of lower genito-urinary tract without periurethral or accessory gland abscess	0.000	0.999	0.001
A56.8 Sexually transmitted chlamydial infection of other sites	0.000	0.999	0.001
A56.4 Chlamydial infection of pharynx	0.000	0.999	0.001
A56.3 Chlamydial infection of anus and rectum	0.000	0.999	0.001
A56.2 Chlamydial infection of genito-urinary tract, unspecified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations