TreeWAS – Variant ID: rs6890562

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N93.8 Other specified abnormal uterine and vaginal bleeding	0.013	0.987	0.000
M20.2 Hallux rigidus	0.009	0.991	0.000
M20.1 Hallux valgus (acquired)	0.008	0.992	0.000
K50.9 Crohn's disease, unspecified	0.000	0.992	0.008
K50 Crohn's disease [regional enteritis]	0.000	0.993	0.007
M20 Acquired deformities of fingers and toes	0.007	0.993	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.993	0.007
K50.1 Crohn's disease of large intestine	0.000	0.993	0.006
M20.0 Deformity of finger(s)	0.006	0.994	0.000
K51 Ulcerative colitis	0.000	0.994	0.006
K50-K52 Noninfective enteritis and colitis	0.000	0.994	0.006
K50.8 Other Crohn's disease	0.000	0.995	0.005
K50.0 Crohn's disease of small intestine	0.000	0.995	0.005
M13.96 Arthritis, unspecified (Lower leg)	0.000	0.995	0.005
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.995	0.005
M20.5 Other deformities of toe(s) (acquired)	0.005	0.995	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.995	0.005
K52 Other non-infective gastro-enteritis and colitis	0.000	0.995	0.005
M20.3 Other deformity of hallux (acquired)	0.004	0.995	0.000
N18.9 Chronic renal failure, unspecified	0.004	0.996	0.000
K51.5 Mucosal proctocolitis	0.000	0.996	0.004
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.996	0.004
K51.8 Other ulcerative colitis	0.000	0.996	0.004
M20.4 Other hammer toe(s) (acquired)	0.004	0.996	0.000
K51.4 Pseudopolyposis of colon	0.000	0.996	0.004
M20.6 Acquired deformity of toe(s), unspecified	0.004	0.996	0.000
K52.1 Toxic gastro-enteritis and colitis	0.000	0.996	0.004
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.996	0.004
Y45.0 Opioids and related analgesics	0.004	0.996	0.000
M13.94 Arthritis, unspecified (Hand)	0.000	0.996	0.004
M13.9 Arthritis, unspecified	0.000	0.996	0.004
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.996	0.003
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.996	0.003
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.996	0.003
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.004	0.996	0.000
O36.4 Maternal care for intra-uterine death	0.003	0.997	0.000
O36 Maternal care for other known or suspected foetal problems	0.003	0.997	0.000
O36.5 Maternal care for poor foetal growth	0.003	0.997	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.003	0.997	0.000
N93 Other abnormal uterine and vaginal bleeding	0.003	0.997	0.000
K52.3 Indeterminate colitis	0.000	0.997	0.003
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
I31.9 Disease of pericardium, unspecified	0.003	0.997	0.000
Y45.8 Other analgesics and antipyretics	0.003	0.997	0.000
Y45.2 Propionic acid derivatives	0.003	0.997	0.000
Y43 Primarily systemic agents	0.003	0.997	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
I31 Other diseases of pericardium	0.003	0.997	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.000	0.997	0.003
Y52 Agents primarily affecting the cardiovascular system	0.003	0.997	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
I51.8 Other ill-defined heart diseases	0.003	0.997	0.000
Y45.1 Salicylates	0.003	0.997	0.000
I44.6 Other and unspecified fascicular block	0.003	0.997	0.000
O36.6 Maternal care for excessive foetal growth	0.003	0.997	0.000
Y43.3 Other antineoplastic drugs	0.003	0.997	0.000
I34 Nonrheumatic mitral valve disorders	0.003	0.997	0.000
Y43.4 Immunosuppressive agents	0.003	0.997	0.000
N18 Chronic renal failure	0.003	0.997	0.000
M13.93 Arthritis, unspecified (Forearm)	0.000	0.997	0.003
M13.92 Arthritis, unspecified (Upper arm)	0.000	0.997	0.003
I51 Complications and ill-defined descriptions of heart disease	0.003	0.997	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.000	0.997	0.003
O36.8 Maternal care for other specified foetal problems	0.003	0.997	0.000
I45.9 Conduction disorder, unspecified	0.003	0.997	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.003	0.997	0.000
Y45.5 4-Aminophenol derivatives	0.003	0.997	0.000
Y45.4 Antirheumatics	0.003	0.997	0.000
O36.9 Maternal care for foetal problem, unspecified	0.003	0.997	0.000
I44 Atrioventricular and left bundle-branch block	0.003	0.997	0.000
I31.3 Pericardial effusion (noninflammatory)	0.003	0.997	0.000
K01.1 Impacted teeth	0.000	0.997	0.003
M13.98 Arthritis, unspecified (Other)	0.000	0.997	0.003
I49.8 Other specified cardiac arrhythmias	0.003	0.997	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.003	0.997	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.003	0.997	0.000
O36.2 Maternal care for hydrops foetalis	0.003	0.997	0.000
O36.1 Maternal care for other isoimmunisation	0.003	0.997	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.003	0.997	0.000
I34.1 Mitral (valve) prolapse	0.003	0.997	0.000
I30-I52 Other forms of heart disease	0.003	0.997	0.000
I44.0 Atrioventricular block, first degree	0.003	0.997	0.000
H81.0 Meniere's disease	0.003	0.997	0.000
I34.0 Mitral (valve) insufficiency	0.003	0.997	0.000
I50.1 Left ventricular failure	0.003	0.997	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.000	0.997	0.002
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.997	0.000
I45 Other conduction disorders	0.003	0.997	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.003	0.997	0.000
I51.4 Myocarditis, unspecified	0.002	0.997	0.000
N18.3 Chronic kidney disease, stage 3	0.003	0.997	0.000
Y43.9 Primarily systemic agent, unspecified	0.002	0.997	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.002	0.997	0.000
Y43.6 Enzymes, not elsewhere classified	0.002	0.997	0.000
Y43.5 Acidifying and alkalising agents	0.002	0.997	0.000
Y43.2 Antineoplastic natural products	0.002	0.997	0.000
Y43.1 Antineoplastic antimetabolites	0.002	0.997	0.000
Y43.0 Antiallergic and antiemetic drugs	0.002	0.997	0.000
I51.7 Cardiomegaly	0.003	0.997	0.000
I51.6 Cardiovascular disease, unspecified	0.002	0.997	0.000
N18.0 End-stage renal disease	0.002	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.997	0.000
I49 Other cardiac arrhythmias	0.003	0.997	0.000
I31.8 Other specified diseases of pericardium	0.002	0.997	0.000
I31.2 Haemopericardium, not elsewhere classified	0.002	0.997	0.000
I31.1 Chronic constrictive pericarditis	0.002	0.997	0.000
I31.0 Chronic adhesive pericarditis	0.002	0.997	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.998	0.002
C44.4 Skin of scalp and neck	0.000	0.998	0.002
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.002	0.998	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.002	0.998	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.002	0.998	0.000
N18.4 Chronic kidney disease, stage 4	0.002	0.998	0.000
I46 Cardiac arrest	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
I51.5 Myocardial degeneration	0.002	0.998	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.002	0.998	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.002	0.998	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.002	0.998	0.000
I51.0 Cardiac septal defect, acquired	0.002	0.998	0.000
N18.8 Other chronic renal failure	0.002	0.998	0.000
N18.1 Chronic kidney disease, stage 1	0.002	0.998	0.000
F32.9 Depressive episode, unspecified	0.000	0.998	0.002
N18.5 Chronic kidney disease, stage 5	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
I44.5 Left posterior fascicular block	0.002	0.998	0.000
I44.4 Left anterior fascicular block	0.002	0.998	0.000
I44.3 Other and unspecified atrioventricular block	0.002	0.998	0.000
I45.2 Bifascicular block	0.002	0.998	0.000
I44.2 Atrioventricular block, complete	0.002	0.998	0.000
W22.9 Unspecified place	0.002	0.998	0.000
I49.5 Sick sinus syndrome	0.002	0.998	0.000
I46.9 Cardiac arrest, unspecified	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.002	0.998	0.000
I52 Other heart disorders in diseases classified elsewhere	0.002	0.998	0.000
I48 Atrial fibrillation and flutter	0.002	0.998	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.002	0.998	0.000
I41 Myocarditis in diseases classified elsewhere	0.002	0.998	0.000
I40 Acute myocarditis	0.002	0.998	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I37 Pulmonary valve disorders	0.002	0.998	0.000
I36 Nonrheumatic tricuspid valve disorders	0.002	0.998	0.000
I32 Pericarditis in diseases classified elsewhere	0.002	0.998	0.000
I49.0 Ventricular fibrillation and flutter	0.002	0.998	0.000
I63.9 Cerebral infarction, unspecified	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
I45.8 Other specified conduction disorders	0.002	0.998	0.000
I45.5 Other specified heart block	0.002	0.998	0.000
I45.4 Nonspecific intraventricular block	0.002	0.998	0.000
I45.3 Trifascicular block	0.002	0.998	0.000
I45.0 Right fascicular block	0.002	0.998	0.000
N18.2 Chronic kidney disease, stage 2	0.002	0.998	0.000
C18.2 Ascending colon	0.002	0.998	0.000
I44.1 Atrioventricular block, second degree	0.002	0.998	0.000
I30 Acute pericarditis	0.002	0.998	0.000
W22 Striking against or struck by other objects	0.002	0.998	0.000
C71.1 Frontal lobe	0.002	0.998	0.000
I45.6 Preexcitation syndrome	0.002	0.998	0.000
I49.2 Junctional premature depolarisation	0.002	0.998	0.000
I49.1 Atrial premature depolarisation	0.002	0.998	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.002	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
C71.9 Brain, unspecified	0.002	0.998	0.000
C71.4 Occipital lobe	0.002	0.998	0.000
C71 Malignant neoplasm of brain	0.002	0.998	0.000
I71 Aortic aneurysm and dissection	0.002	0.998	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.998	0.002
I50 Heart failure	0.002	0.998	0.000
I33 Acute and subacute endocarditis	0.002	0.998	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y41.5 Antiviral drugs	0.002	0.998	0.000
Y41.4 Anthelminthics	0.002	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
Y41.0 Sulphonamides	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.4 Iminostilbenes	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.002	0.998	0.000
Y48.3 Local anaesthetics	0.002	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000
Y48.0 Inhaled anaesthetics	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
I49.3 Ventricular premature depolarisation	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
W20-W49 Exposure to inanimate mechanical forces	0.002	0.998	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.998	0.002
F32 Depressive episode	0.000	0.998	0.002
M13 Other arthritis	0.000	0.998	0.002
C71.0 Cerebrum, except lobes and ventricles	0.002	0.998	0.000
I46.1 Sudden cardiac death, so described	0.002	0.998	0.000
Y42.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
Y42.4 Oral contraceptives	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.002	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
I49.4 Other and unspecified premature depolarisation	0.002	0.998	0.000
K29.5 Chronic gastritis, unspecified	0.002	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.002	0.998	0.000
I74 Arterial embolism and thrombosis	0.002	0.998	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.002	0.998	0.000
W08.0 Home	0.002	0.998	0.000
W23.4 Street and highway	0.002	0.998	0.000
C18 Malignant neoplasm of colon	0.002	0.998	0.000
M20-M25 Other joint disorders	0.002	0.998	0.000
C18.3 Hepatic flexure	0.002	0.998	0.000
M25.78 Osteophyte (Other)	0.002	0.998	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.002	0.998	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.002	0.998	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.002	0.998	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.002	0.998	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.002	0.998	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.002	0.998	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.002	0.998	0.000
I37.9 Pulmonary valve disorder, unspecified	0.002	0.998	0.000
I37.8 Other pulmonary valve disorders	0.002	0.998	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.002	0.998	0.000
I37.1 Pulmonary valve insufficiency	0.002	0.998	0.000
I37.0 Pulmonary valve stenosis	0.002	0.998	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.002	0.998	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I40.9 Acute myocarditis, unspecified	0.002	0.998	0.000
I40.8 Other acute myocarditis	0.002	0.998	0.000
I40.1 Isolated myocarditis	0.002	0.998	0.000
I40.0 Infective myocarditis	0.002	0.998	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.002	0.998	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.002	0.998	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.002	0.998	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.002	0.998	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.002	0.998	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.002	0.998	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I44.7 Left bundle-branch block, unspecified	0.002	0.998	0.000
I46.0 Cardiac arrest with successful resuscitation	0.002	0.998	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.002	0.998	0.000
I48.4 Atypical atrial flutter	0.002	0.998	0.000
I48.3 Typical atrial flutter	0.002	0.998	0.000
I48.2 Chronic atrial fibrillation	0.002	0.998	0.000
I48.1 Persistent atrial fibrillation	0.002	0.998	0.000
I48.0 Paroxysmal atrial fibrillation	0.002	0.998	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.002	0.998	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.002	0.998	0.000
C18.7 Sigmoid colon	0.002	0.998	0.000
C18.0 Caecum	0.002	0.998	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.002	0.998	0.000
F32.1 Moderate depressive episode	0.000	0.998	0.002
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
M81.98 Osteoporosis, unspecified (Other)	0.000	0.998	0.002
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
H81 Disorders of vestibular function	0.002	0.998	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.998	0.002
J32.9 Chronic sinusitis, unspecified	0.000	0.998	0.002
Y42.5 Other oestrogens and progestogens	0.002	0.998	0.000
I30.8 Other forms of acute pericarditis	0.002	0.998	0.000
I30.1 Infective pericarditis	0.002	0.998	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.002	0.998	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.002	0.998	0.000
W22.8 Other specified place	0.002	0.998	0.000
W22.6 Industrial and construction area	0.002	0.998	0.000
W22.4 Street and highway	0.002	0.998	0.000
W22.0 Home	0.002	0.998	0.000
W22.7 Farm	0.002	0.998	0.000
W22.5 Trade and service area	0.002	0.998	0.000
W22.3 Sports and athletics area	0.002	0.998	0.000
W22.2 School, other institution and public administrative area	0.002	0.998	0.000
W22.1 Residential institution	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
M24 Other specific joint derangements	0.002	0.998	0.000
I71.0 Dissection of aorta [any part]	0.002	0.998	0.000
W29 Contact with other powered hand tools and household machinery	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
C71.7 Brain stem	0.002	0.998	0.000
C71.6 Cerebellum	0.002	0.998	0.000
C71.5 Cerebral ventricle	0.002	0.998	0.000
C71.3 Parietal lobe	0.002	0.998	0.000
C71.2 Temporal lobe	0.002	0.998	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.002	0.998	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.002	0.998	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.002	0.998	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.002	0.998	0.000
M13.0 Polyarthritis, unspecified	0.000	0.998	0.002
M35 Other systemic involvement of connective tissue	0.002	0.998	0.000
I33.9 Acute endocarditis, unspecified	0.002	0.998	0.000
I51.9 Heart disease, unspecified	0.002	0.998	0.000
M81.9 Osteoporosis, unspecified	0.000	0.998	0.002
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.002	0.998	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.998	0.002
Y57.9 Drug or medicament, unspecified	0.001	0.998	0.000
W08 Fall involving other furniture	0.002	0.998	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.002	0.998	0.000
C18.9 Colon, unspecified	0.002	0.998	0.000
F32.8 Other depressive episodes	0.000	0.998	0.002
M13.8 Other specified arthritis	0.000	0.998	0.002
M13.1 Monoarthritis, not elsewhere classified	0.000	0.998	0.002
M35.1 Other overlap syndromes	0.002	0.998	0.000
N93.0 Postcoital and contact bleeding	0.002	0.998	0.000
W19.9 Unspecified place	0.000	0.998	0.002
I64 Stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.002	0.998	0.000
W46 Contact with hypodermic needle	0.002	0.998	0.000
W45 Foreign body or object entering through skin	0.002	0.998	0.000
W43 Exposure to vibration	0.002	0.998	0.000
W42 Exposure to noise	0.002	0.998	0.000
W41 Exposure to high-pressure jet	0.002	0.998	0.000
W40 Explosion of other materials	0.002	0.998	0.000
W39 Discharge of firework	0.002	0.998	0.000
W38 Explosion and rupture of other specified pressurised devices	0.002	0.998	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.002	0.998	0.000
W36 Explosion and rupture of gas cylinder	0.002	0.998	0.000
W35 Explosion and rupture of boiler	0.002	0.998	0.000
W34 Discharge from other and unspecified firearms	0.002	0.998	0.000
W33 Rifle, shotgun and larger firearm discharge	0.002	0.998	0.000
W32 Handgun discharge	0.002	0.998	0.000
W31 Contact with other and unspecified machinery	0.002	0.998	0.000
W30 Contact with agricultural machinery	0.002	0.998	0.000
W28 Contact with powered lawn mower	0.002	0.998	0.000
W27 Contact with nonpowered hand tool	0.002	0.998	0.000
W26 Contact with knife, sword or dagger	0.002	0.998	0.000
W25 Contact with sharp glass	0.002	0.998	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.002	0.998	0.000
W21 Striking against or struck by sports equipment	0.002	0.998	0.000
W20 Struck by thrown, projected or falling object	0.002	0.998	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.998	0.002
F32.0 Mild depressive episode	0.000	0.998	0.002
I30.9 Acute pericarditis, unspecified	0.001	0.998	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.002	0.998	0.000
M35.3 Polymyalgia rheumatica	0.002	0.998	0.000
I42 Cardiomyopathy	0.002	0.998	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.998	0.002
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.000	0.998	0.002
W44 Foreign body entering into or through eye or natural orifice	0.002	0.998	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.002	0.998	0.000
I74.8 Embolism and thrombosis of other arteries	0.002	0.998	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.002	0.998	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.002	0.998	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.002	0.998	0.000
V23.4 Driver injured in traffic accident	0.002	0.998	0.000
W23.9 Unspecified place	0.001	0.998	0.000
W23.8 Other specified place	0.001	0.998	0.000
W23.6 Industrial and construction area	0.001	0.998	0.000
W23.5 Trade and service area	0.001	0.998	0.000
W23.0 Home	0.001	0.998	0.000
W23.7 Farm	0.001	0.998	0.000
W23.3 Sports and athletics area	0.001	0.998	0.000
W23.2 School, other institution and public administrative area	0.001	0.998	0.000
W23.1 Residential institution	0.001	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.001	0.998	0.000
M34 Systemic sclerosis	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations