TreeWAS – Variant ID: rs6936204

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
K90.0 Coeliac disease	1.000	0.000	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
G35 Multiple sclerosis	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
Chapter I Certain infectious and parasitic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
G35-G37 Demyelinating diseases of the central nervous system	1.000	0.000	0.000
E27 Other disorders of adrenal gland	1.000	0.000	0.000
E27.1 Primary adrenocortical insufficiency	1.000	0.000	0.000
M06 Other rheumatoid arthritis	0.000	0.000	1.000
Chapter VI Diseases of the nervous system	1.000	0.000	0.000
E20-E35 Disorders of other endocrine glands	1.000	0.000	0.000
B37.8 Candidiasis of other sites	1.000	0.000	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
B37 Candidiasis	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
B35-B49 Mycoses	0.999	0.001	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.999	0.001	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.001	0.999
D69 Purpura and other haemorrhagic conditions	0.997	0.003	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.005	0.995
Chapter XII Diseases of the skin and subcutaneous tissue	0.995	0.005	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.006	0.994
D80-D89 Certain disorders involving the immune mechanism	0.991	0.009	0.000
M05-M14 Inflammatory polyarthropathies	0.000	0.009	0.991
M06.3 Rheumatoid nodule	0.000	0.011	0.989
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.987	0.013	0.000
L50-L54 Urticaria and erythema	0.987	0.013	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.987	0.013	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.013	0.987
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.987	0.013	0.000
D50-D53 Nutritional anaemias	0.986	0.014	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.985	0.015	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.983	0.017	0.000
D86 Sarcoidosis	0.981	0.019	0.000
B07 Viral warts	0.980	0.020	0.000
D69.6 Thrombocytopenia, unspecified	0.979	0.021	0.000
E50-E64 Other nutritional deficiencies	0.977	0.023	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.976	0.024	0.000
Chapter II Neoplasms	0.976	0.024	0.000
L20-L30 Dermatitis and eczema	0.975	0.025	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.027	0.973
C34 Malignant neoplasm of bronchus and lung	0.973	0.027	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.972	0.028	0.000
E04 Other non-toxic goitre	0.971	0.029	0.000
K90 Intestinal malabsorption	0.971	0.029	0.000
A63.0 Anogenital (venereal) warts	0.969	0.031	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.031	0.969
D51 Vitamin B12 deficiency anaemia	0.964	0.036	0.000
G37 Other demyelinating diseases of central nervous system	0.961	0.039	0.000
E27.2 Addisonian crisis	0.959	0.041	0.000
L27 Dermatitis due to substances taken internally	0.959	0.041	0.000
C34.9 Bronchus or lung, unspecified	0.958	0.042	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.951	0.049	0.000
D86.9 Sarcoidosis, unspecified	0.950	0.050	0.000
G40-G47 Episodic and paroxysmal disorders	0.949	0.051	0.000
L53 Other erythematous conditions	0.947	0.053	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.055	0.945
D52 Folate deficiency anaemia	0.943	0.057	0.000
B25-B34 Other viral diseases	0.941	0.059	0.000
D55-D59 Haemolytic anaemias	0.940	0.060	0.000
G40 Epilepsy	0.940	0.060	0.000
L10-L14 Bullous disorders	0.939	0.061	0.000
D68 Other coagulation defects	0.939	0.061	0.000
C91 Lymphoid leukaemia	0.938	0.062	0.000
C34.3 Lower lobe, bronchus or lung	0.937	0.063	0.000
B37.9 Candidiasis, unspecified	0.936	0.064	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.936	0.064	0.000
E04.0 Non-toxic diffuse goitre	0.935	0.065	0.000
E55 Vitamin D deficiency	0.933	0.067	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.932	0.068	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.075	0.925
G20-G26 Extrapyramidal and movement disorders	0.923	0.077	0.000
L52 Erythema nodosum	0.922	0.078	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.078	0.922
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.918	0.082	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.917	0.083	0.000
D59 Acquired haemolytic anaemia	0.912	0.088	0.000
D52.9 Folate deficiency anaemia, unspecified	0.912	0.088	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.907	0.093	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.905	0.095	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.096	0.904
L13 Other bullous disorders	0.904	0.096	0.000
C88 Malignant immunoproliferative diseases	0.902	0.098	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.098	0.902
E55.9 Vitamin D deficiency, unspecified	0.902	0.098	0.000
G20 Parkinson's disease	0.899	0.101	0.000
B25 Cytomegaloviral disease	0.897	0.103	0.000
L53.9 Erythematous condition, unspecified	0.897	0.103	0.000
D69.4 Other primary thrombocytopenia	0.897	0.103	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.895	0.105	0.000
C85.1 B-cell lymphoma, unspecified	0.893	0.107	0.000
E04.2 Non-toxic multinodular goitre	0.892	0.108	0.000
E34 Other endocrine disorders	0.889	0.111	0.000
L21 Seborrhoeic dermatitis	0.888	0.112	0.000
D86.3 Sarcoidosis of skin	0.885	0.115	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.118	0.882
C85.7 Other specified types of non-Hodgkin's lymphoma	0.879	0.121	0.000
L13.0 Dermatitis herpetiformis	0.878	0.122	0.000
K90.9 Intestinal malabsorption, unspecified	0.873	0.127	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.128	0.872
E53 Deficiency of other B group vitamins	0.871	0.129	0.000
D59.1 Other autoimmune haemolytic anaemias	0.865	0.135	0.000
B25.9 Cytomegaloviral disease, unspecified	0.864	0.136	0.000
B37.0 Candidal stomatitis	0.861	0.139	0.000
D69.8 Other specified haemorrhagic conditions	0.859	0.141	0.000
E22 Hyperfunction of pituitary gland	0.859	0.141	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.151	0.849
D68.0 Von Willebrand's disease	0.849	0.151	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.152	0.848
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.847	0.153	0.000
L40-L45 Papulosquamous disorders	0.846	0.154	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.845	0.155	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.839	0.161	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.838	0.162	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.838	0.162	0.000
L50 Urticaria	0.836	0.164	0.000
C34.2 Middle lobe, bronchus or lung	0.834	0.166	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.169	0.831
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.829	0.171	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.826	0.174	0.000
E31 Polyglandular dysfunction	0.820	0.180	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.817	0.183	0.000
E27.8 Other specified disorders of adrenal gland	0.816	0.184	0.000
D68.9 Coagulation defect, unspecified	0.815	0.185	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.815	0.185	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.815	0.185	0.000
G40.5 Special epileptic syndromes	0.814	0.186	0.000
L40 Psoriasis	0.812	0.188	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.189	0.811
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.190	0.810
E34.0 Carcinoid syndrome	0.810	0.190	0.000
E07 Other disorders of thyroid	0.809	0.191	0.000
L53.0 Toxic erythema	0.809	0.191	0.000
L23 Allergic contact dermatitis	0.808	0.192	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.192	0.808
B37.1 Pulmonary candidiasis	0.808	0.192	0.000
D68.6 Other Thrombophilia	0.806	0.194	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.803	0.197	0.000
L40.9 Psoriasis, unspecified	0.802	0.198	0.000
D72 Other disorders of white blood cells	0.799	0.201	0.000
C51-C58 Malignant neoplasms of female genital organs	0.799	0.201	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.798	0.202	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.797	0.203	0.000
C91.4 Hairy-cell leukaemia	0.796	0.204	0.000
C91.1 Chronic lymphocytic leukaemia	0.796	0.204	0.000
M45 Ankylosing spondylitis	0.000	0.206	0.794
D86.0 Sarcoidosis of lung	0.794	0.206	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.793	0.207	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.792	0.208	0.000
C34.0 Main bronchus	0.792	0.208	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.211	0.789
E51 Thiamine deficiency	0.789	0.211	0.000
B00 Herpesviral [herpes simplex] infections	0.789	0.211	0.000
E53.8 Deficiency of other specified B group vitamins	0.786	0.214	0.000
D69.2 Other nonthrombocytopenic purpura	0.786	0.214	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.785	0.215	0.000
C84.4 Peripheral T-cell lymphoma	0.784	0.216	0.000
D82 Immunodeficiency associated with other major defects	0.781	0.219	0.000
A30-A49 Other bacterial diseases	0.778	0.222	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.778	0.222	0.000
G00 Bacterial meningitis, not elsewhere classified	0.775	0.225	0.000
E20 Hypoparathyroidism	0.775	0.225	0.000
C84.5 Other and unspecified T-cell lymphomas	0.775	0.225	0.000
G41 Status epilepticus	0.774	0.226	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.230	0.769
C88.0 Waldenstrom's macroglobulinaemia	0.769	0.231	0.000
E04.9 Non-toxic goitre, unspecified	0.769	0.231	0.000
E27.9 Disorder of adrenal gland, unspecified	0.768	0.232	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.766	0.234	0.000
B37.2 Candidiasis of skin and nail	0.765	0.235	0.000
A80-A89 Viral infections of the central nervous system	0.765	0.235	0.000
E07.8 Other specified disorders of thyroid	0.764	0.236	0.000
D73 Diseases of spleen	0.763	0.237	0.000
B01 Varicella [chickenpox]	0.761	0.239	0.000
D84 Other immunodeficiencies	0.761	0.239	0.000
C34.8 Overlapping lesion of bronchus and lung	0.760	0.240	0.000
C86 Other specified types of T/NK-cell lymphoma	0.758	0.242	0.000
A41 Other septicaemia	0.756	0.244	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.753	0.247	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.752	0.248	0.000
L25 Unspecified contact dermatitis	0.752	0.248	0.000
D72.8 Other specified disorders of white blood cells	0.751	0.249	0.000
E63 Other nutritional deficiencies	0.749	0.251	0.000
L50.1 Idiopathic urticaria	0.748	0.252	0.000
A63.8 Other specified predominantly sexually transmitted diseases	0.747	0.253	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.747	0.253	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.747	0.253	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.743	0.256	0.000
A41.9 Septicaemia, unspecified	0.743	0.257	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.257	0.743
C91.5 Adult T-cell leukaemia	0.743	0.257	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.742	0.258	0.000
C31 Malignant neoplasm of accessory sinuses	0.741	0.259	0.000
L20 Atopic dermatitis	0.741	0.259	0.000
D69.5 Secondary thrombocytopenia	0.740	0.260	0.000
L11 Other acantholytic disorders	0.739	0.261	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.738	0.261	0.000
B37.4 Candidiasis of other urogenital sites	0.736	0.263	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.734	0.266	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.732	0.268	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.269	0.731
G44 Other headache syndromes	0.731	0.269	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.730	0.270	0.000
C91.0 Acute lymphoblastic leukaemia	0.730	0.270	0.000
G30-G32 Other degenerative diseases of the nervous system	0.730	0.270	0.000
G24 Dystonia	0.728	0.272	0.000
D70 Agranulocytosis	0.724	0.276	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.724	0.276	0.000
C94 Other leukaemias of specified cell type	0.723	0.277	0.000
A65-A69 Other spirochaetal diseases	0.722	0.278	0.000
C91.9 Lymphoid leukaemia, unspecified	0.720	0.280	0.000
K90.8 Other intestinal malabsorption	0.720	0.280	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.719	0.281	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.283	0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.283	0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.283	0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.283	0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.283	0.717
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.717	0.283	0.000
A75-A79 Rickettsioses	0.717	0.283	0.000
A70-A74 Other diseases caused by chlamydiae	0.717	0.283	0.000
A20-A28 Certain zoonotic bacterial diseases	0.717	0.283	0.000
E27.5 Adrenomedullary hyperfunction	0.717	0.283	0.000
E27.0 Other adrenocortical overactivity	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.000	0.283	0.717
M06.1 Adult-onset Still's disease	0.000	0.283	0.717
E35 Disorders of endocrine glands in diseases classified elsewhere	0.717	0.283	0.000
E32 Diseases of thymus	0.717	0.283	0.000
E30 Disorders of puberty, not elsewhere classified	0.717	0.283	0.000
E25 Adrenogenital disorders	0.717	0.283	0.000
B37.6 Candidal endocarditis	0.717	0.283	0.000
B37.5 Candidal meningitis	0.717	0.283	0.000
B48 Other mycoses, not elsewhere classified	0.716	0.283	0.000
B47 Mycetoma	0.716	0.283	0.000
B46 Zygomycosis	0.716	0.283	0.000
B45 Cryptococcosis	0.716	0.283	0.000
B43 Chromomycosis and phaeomycotic abscess	0.716	0.283	0.000
B42 Sporotrichosis	0.716	0.283	0.000
B41 Paracoccidioidomycosis	0.716	0.283	0.000
B40 Blastomycosis	0.716	0.283	0.000
B39 Histoplasmosis	0.716	0.283	0.000
B38 Coccidioidomycosis	0.716	0.283	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.716	0.284	0.000
D86.8 Sarcoidosis of other and combined sites	0.714	0.286	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.714	0.286	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.286	0.713
M05.2 Rheumatoid vasculitis	0.000	0.286	0.713
M05.1 Rheumatoid lung disease	0.000	0.286	0.713
M05.0 Felty's syndrome	0.000	0.286	0.713
D66 Hereditary factor VIII deficiency	0.712	0.288	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.711	0.289	0.000
D81 Combined immunodeficiencies	0.711	0.289	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.289	0.710
M08 Juvenile arthritis	0.000	0.289	0.710
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.710	0.290	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.709	0.290	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.291	0.709
M06.38 Rheumatoid nodule (Other)	0.000	0.291	0.709
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.291	0.709
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.291	0.709
M06.33 Rheumatoid nodule (Forearm)	0.000	0.291	0.709
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.291	0.709
C85.0 Lymphosarcoma	0.708	0.292	0.000
L54 Erythema in diseases classified elsewhere	0.708	0.292	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.708	0.292	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.708	0.292	0.000
C90.3 Solitary plasmacytoma	0.708	0.292	0.000
B06 Rubella [German measles]	0.707	0.292	0.000
B05 Measles	0.707	0.292	0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.707	0.292	0.000
B04 Monkeypox	0.707	0.292	0.000
B03 Smallpox	0.707	0.292	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.707	0.293	0.000
B34 Viral infection of unspecified site	0.707	0.293	0.000
B37.7 Candidal septicaemia	0.706	0.294	0.000
A59 Trichomoniasis	0.706	0.294	0.000
A56 Other sexually transmitted chlamydial diseases	0.706	0.294	0.000
A54 Gonococcal infection	0.706	0.294	0.000
A53 Other and unspecified syphilis	0.706	0.294	0.000
A52 Late syphilis	0.706	0.294	0.000
A51 Early syphilis	0.706	0.294	0.000
A50 Congenital syphilis	0.706	0.294	0.000
A64 Unspecified sexually transmitted disease	0.706	0.294	0.000
A58 Granuloma inguinale	0.706	0.294	0.000
A57 Chancroid	0.706	0.294	0.000
A55 Chlamydial lymphogranuloma (venereum)	0.706	0.294	0.000
B36 Other superficial mycoses	0.706	0.294	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.703	0.297	0.000
M12 Other specific arthropathies	0.000	0.299	0.701
M14 Arthropathies in other diseases classified elsewhere	0.000	0.299	0.701
G41.0 Grand mal status epilepticus	0.701	0.299	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.701	0.299	0.000
E50 Vitamin A deficiency	0.701	0.299	0.000
E60 Dietary zinc deficiency	0.701	0.299	0.000
E59 Dietary selenium deficiency	0.701	0.299	0.000
E54 Ascorbic acid deficiency	0.701	0.299	0.000
E52 Niacin deficiency [pellagra]	0.701	0.299	0.000
L24 Irritant contact dermatitis	0.699	0.301	0.000
L26 Exfoliative dermatitis	0.699	0.301	0.000
L22 Diaper [napkin] dermatitis	0.699	0.301	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.699	0.301	0.000
B24 Unspecified human immunodeficiency virus [HIV] disease	0.699	0.301	0.000
G36 Other acute disseminated demyelination	0.699	0.301	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.699	0.301	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.698	0.302	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.302	0.698
E05.8 Other thyrotoxicosis	0.698	0.302	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.303	0.697
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.697	0.303	0.000
E04.8 Other specified non-toxic goitre	0.696	0.303	0.000
K90.3 Pancreatic steatorrhoea	0.696	0.304	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.696	0.304	0.000
K90.1 Tropical sprue	0.696	0.304	0.000
B65-B83 Helminthiases	0.693	0.307	0.000
E31.0 Autoimmune polyglandular failure	0.692	0.308	0.000
L51 Erythema multiforme	0.691	0.308	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.691	0.309	0.000
D51.2 Transcobalamin II deficiency	0.691	0.309	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.691	0.309	0.000
B15-B19 Viral hepatitis	0.690	0.310	0.000
G37.5 Concentric sclerosis [Balo]	0.689	0.311	0.000
G37.4 Subacute necrotising myelitis	0.689	0.311	0.000
G37.2 Central pontine myelinolysis	0.689	0.311	0.000
G37.1 Central demyelination of corpus callosum	0.689	0.311	0.000
G37.0 Diffuse sclerosis	0.689	0.311	0.000
L27.9 Dermatitis due to unspecified substance taken internally	0.687	0.313	0.000
L27.8 Dermatitis due to other substances taken internally	0.687	0.313	0.000
B30 Viral conjunctivitis	0.687	0.313	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.314	0.686
D69.1 Qualitative platelet defects	0.686	0.314	0.000
Chapter XXII Codes for special purposes	0.685	0.315	0.000
D86.1 Sarcoidosis of lymph nodes	0.684	0.315	0.000
E28 Ovarian dysfunction	0.681	0.319	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.681	0.319	0.000
E22.0 Acromegaly and pituitary gigantism	0.680	0.320	0.000
L53.3 Other chronic figurate erythema	0.679	0.321	0.000
L53.2 Erythema marginatum	0.679	0.321	0.000
L53.1 Erythema annulare centrifugum	0.679	0.321	0.000
C80 Malignant neoplasm without specification of site	0.679	0.321	0.000
B33 Other viral diseases, not elsewhere classified	0.678	0.321	0.000
C81 Hodgkin's disease	0.679	0.321	0.000
D52.8 Other folate deficiency anaemias	0.676	0.324	0.000
D52.1 Drug-induced folate deficiency anaemia	0.676	0.324	0.000
D52.0 Dietary folate deficiency anaemia	0.676	0.324	0.000
C33 Malignant neoplasm of trachea	0.675	0.325	0.000
B26 Mumps	0.675	0.325	0.000
B25.0 Cytomegaloviral pneumonitis	0.675	0.325	0.000
D57 Sickle-cell disorders	0.674	0.326	0.000
D55 Anaemia due to enzyme disorders	0.674	0.326	0.000
L14 Bullous disorders in diseases classified elsewhere	0.673	0.327	0.000
C93 Monocytic leukaemia	0.673	0.327	0.000
C95 Leukaemia of unspecified cell type	0.673	0.327	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.672	0.328	0.000
C91.7 Other lymphoid leukaemia	0.672	0.328	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.672	0.328	0.000
C91.3 Prolymphocytic leukaemia	0.672	0.328	0.000
C91.2 Subacute lymphocytic leukaemia	0.672	0.328	0.000
E34.8 Other specified endocrine disorders	0.672	0.328	0.000
C38.4 Pleura	0.671	0.329	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.671	0.329	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.670	0.330	0.000
G00.9 Bacterial meningitis, unspecified	0.670	0.330	0.000
E55.0 Rickets, active	0.669	0.331	0.000
C78.2 Secondary malignant neoplasm of pleura	0.669	0.331	0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.666	0.334	0.000
C52 Malignant neoplasm of vagina	0.666	0.334	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.665	0.335	0.000
B00.5 Herpesviral ocular disease	0.664	0.336	0.000
D56 Thalassaemia	0.664	0.336	0.000
D76.3 Other histiocytosis syndromes	0.664	0.336	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.337	0.663
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.337	0.663
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.337	0.663
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.337	0.663
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.337	0.663
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.337	0.663
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.337	0.663
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.337	0.663
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.661	0.338	0.000
G22 Parkinsonism in diseases classified elsewhere	0.661	0.338	0.000
C84.0 Mycosis fungoides	0.661	0.339	0.000
G24.9 Dystonia, unspecified	0.660	0.340	0.000
D80 Immunodeficiency with predominantly antibody defects	0.659	0.341	0.000
D83 Common variable immunodeficiency	0.657	0.343	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.657	0.343	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.657	0.343	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.657	0.343	0.000
C84.3 Lymphoepithelioid lymphoma	0.657	0.343	0.000
C84.2 T-zone lymphoma	0.657	0.343	0.000
C84.1 Sezary's diease	0.657	0.343	0.000
D60-D64 Aplastic and other anaemias	0.657	0.343	0.000
L50.8 Other urticaria	0.657	0.343	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.344	0.656
C53 Malignant neoplasm of cervix uteri	0.654	0.346	0.000
E51.2 Wernicke's encephalopathy	0.654	0.346	0.000
D59.8 Other acquired haemolytic anaemias	0.654	0.346	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.654	0.346	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.654	0.346	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.654	0.346	0.000
D59.3 Haemolytic-uraemic syndrome	0.654	0.346	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.654	0.346	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.654	0.346	0.000
A40 Streptococcal septicaemia	0.652	0.348	0.000
D68.8 Other specified coagulation defects	0.652	0.348	0.000
G44.2 Tension-type headache	0.652	0.348	0.000
E58 Dietary calcium deficiency	0.651	0.349	0.000
D74 Methaemoglobinaemia	0.650	0.349	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.650	0.349	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.650	0.349	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.650	0.350	0.000
L53.8 Other specified erythematous conditions	0.650	0.350	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.649	0.351	0.000
E61 Deficiency of other nutrient elements	0.648	0.351	0.000
G21 Secondary Parkinsonism	0.648	0.351	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.352	0.648
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.352	0.648
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.352	0.648
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.352	0.648
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.352	0.648
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.352	0.648
L13.9 Bullous disorder, unspecified	0.648	0.352	0.000
L13.8 Other specified bullous disorders	0.648	0.352	0.000
L13.1 Subcorneal pustular dermatitis	0.648	0.352	0.000
E53.9 Vitamin B deficiency, unspecified	0.647	0.353	0.000
L40.3 Pustulosis palmaris et plantaris	0.647	0.353	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.647	0.353	0.000
C88.7 Other malignant immunoproliferative diseases	0.647	0.353	0.000
C88.3 Immunoproliferative small intestinal disease	0.647	0.353	0.000
C88.2 Gamma heavy chain disease	0.647	0.353	0.000
C88.1 Alpha heavy chain disease	0.647	0.353	0.000
D67 Hereditary factor IX deficiency	0.646	0.354	0.000
C80.9 Malignant neoplasm, unspecified	0.646	0.354	0.000
L10 Pemphigus	0.645	0.355	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.644	0.356	0.000
B25.2 Cytomegaloviral pancreatitis	0.643	0.357	0.000
B25.1 Cytomegaloviral hepatitis	0.643	0.357	0.000
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions	0.643	0.357	0.000
D53 Other nutritional anaemias	0.641	0.359	0.000
D84.1 Defects in the complement system	0.641	0.359	0.000
L23.9 Allergic contact dermatitis, unspecified cause	0.640	0.360	0.000
E56 Other vitamin deficiencies	0.638	0.361	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.361	0.638
A60 Anogenital herpesviral [herpes simplex] infections	0.638	0.362	0.000
E34.5 Androgen resistance syndrome	0.637	0.362	0.000
E34.4 Constitutional tall stature	0.637	0.362	0.000
E34.3 Short stature, not elsewhere classified	0.637	0.362	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.637	0.362	0.000
E34.1 Other hypersecretion of intestinal hormones	0.637	0.362	0.000
L21.8 Other seborrhoeic dermatitis	0.637	0.363	0.000
L21.1 Seborrhoeic infantile dermatitis	0.637	0.363	0.000
L21.0 Seborrhoea capitis	0.637	0.363	0.000
C90.1 Plasma cell leukaemia	0.636	0.364	0.000
G00.2 Streptococcal meningitis	0.636	0.364	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.635	0.365	0.000
G23 Other degenerative diseases of basal ganglia	0.635	0.365	0.000
L44 Other papulosquamous disorders	0.631	0.369	0.000
B27 Infectious mononucleosis	0.631	0.369	0.000
B50-B64 Protozoal diseases	0.630	0.370	0.000
C04 Malignant neoplasm of floor of mouth	0.630	0.370	0.000
D82.1 Di George's syndrome	0.629	0.370	0.000
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases	0.628	0.372	0.000
D73.1 Hypersplenism	0.628	0.372	0.000
G00.1 Pneumococcal meningitis	0.627	0.372	0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.627	0.373	0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs	0.627	0.373	0.000
L50.0 Allergic urticaria	0.626	0.374	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.626	0.374	0.000
B25.8 Other cytomegaloviral diseases	0.625	0.375	0.000
E53.1 Pyridoxine deficiency	0.624	0.376	0.000
E53.0 Riboflavin deficiency	0.624	0.376	0.000
B00.4 Herpesviral encephalitis	0.623	0.377	0.000
L27.2 Dermatitis due to ingested food	0.621	0.379	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.621	0.379	0.000
E24 Cushing's syndrome	0.620	0.380	0.000
A86 Unspecified viral encephalitis	0.616	0.384	0.000
E22.8 Other hyperfunction of pituitary gland	0.616	0.384	0.000
D68.5 Primary Thrombophilia	0.615	0.385	0.000
E20.9 Hypoparathyroidism, unspecified	0.614	0.386	0.000
C37 Malignant neoplasm of thymus	0.614	0.386	0.000
D61 Other aplastic anaemias	0.613	0.387	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.613	0.387	0.000
L23.5 Allergic contact dermatitis due to other chemical products	0.611	0.389	0.000
C90.0 Multiple myeloma	0.610	0.390	0.000
D73.5 Infarction of spleen	0.610	0.390	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.609	0.391	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations