TreeWAS – Variant ID: rs6971109

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.142	0.858	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.134	0.866	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.134	0.866	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.129	0.871	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.126	0.874	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.124	0.876	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.123	0.877	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.120	0.880	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.118	0.882	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.117	0.883	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.116	0.884	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.115	0.885	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.112	0.888	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.112	0.888	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.108	0.892	0.000
T36 Poisoning by systemic antibiotics	0.108	0.892	0.000
T43.2 Other and unspecified antidepressants	0.108	0.892	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.108	0.892	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.106	0.894	0.000
T40.6 Other and unspecified narcotics	0.105	0.895	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.105	0.895	0.000
T40.2 Other opioids	0.105	0.895	0.000
T40.5 Cocaine	0.104	0.896	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.102	0.898	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.102	0.898	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.102	0.898	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.100	0.900	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.099	0.901	0.000
T40.4 Other synthetic narcotics	0.097	0.903	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.097	0.903	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.097	0.903	0.000
T43.9 Psychotropic drug, unspecified	0.096	0.903	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.096	0.903	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.096	0.904	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.096	0.904	0.000
T46.7 Peripheral vasodilators	0.096	0.904	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.096	0.904	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.096	0.904	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.096	0.904	0.000
T42.1 Iminostilbenes	0.096	0.904	0.000
T46.1 Calcium-channel blockers	0.095	0.905	0.000
T45.0 Antiallergic and antiemetic drugs	0.094	0.906	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.094	0.906	0.000
T47.2 Stimulant laxatives	0.094	0.906	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.092	0.907	0.000
T40.8 Lysergide [LSD]	0.092	0.907	0.000
T40.7 Cannabis (derivatives)	0.092	0.907	0.000
T40.3 Methadone	0.092	0.907	0.000
T40.1 Heroin	0.092	0.907	0.000
T40.0 Opium	0.092	0.907	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.091	0.909	0.000
T42.4 Benzodiazepines	0.090	0.910	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.090	0.910	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.089	0.911	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.089	0.911	0.000
T42.3 Barbiturates	0.089	0.911	0.000
T42.2 Succinimides and oxazolidinediones	0.089	0.911	0.000
T47.0 Histamine H(2)-receptor antagonists	0.089	0.911	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.088	0.912	0.000
T43.6 Psychostimulants with abuse potential	0.086	0.914	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.086	0.914	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.086	0.914	0.000
T47.7 Emetics	0.086	0.914	0.000
T47.6 Antidiarrhoeal drugs	0.086	0.914	0.000
T47.5 Digestants	0.086	0.914	0.000
T47.4 Other laxatives	0.086	0.914	0.000
T47.3 Saline and osmotic laxatives	0.086	0.914	0.000
T36.0 Penicillins	0.084	0.915	0.000
T38.9 Other and unspecified hormone antagonists	0.084	0.916	0.000
T38.7 Androgens and anabolic congeners	0.084	0.916	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.084	0.916	0.000
T38.5 Other oestrogens and progestogens	0.084	0.916	0.000
T38.4 Oral contraceptives	0.084	0.916	0.000
T38.2 Antithyroid drugs	0.084	0.916	0.000
T38.0 Glucocorticoids and synthetic analogues	0.084	0.916	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.084	0.916	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.084	0.916	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.084	0.916	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.084	0.916	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.084	0.916	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.084	0.916	0.000
T44.0 Anticholinesterase agents	0.084	0.916	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.082	0.918	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.081	0.919	0.000
T37.5 Antiviral drugs	0.081	0.919	0.000
T37.4 Anthelminthics	0.081	0.919	0.000
T37.3 Other antiprotozoal drugs	0.081	0.919	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.081	0.919	0.000
T37.1 Antimycobacterial drugs	0.081	0.919	0.000
T37.0 Sulphonamides	0.081	0.919	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.081	0.919	0.000
T38.1 Thyroid hormones and substitutes	0.079	0.921	0.000
T42.0 Hydantoin derivatives	0.079	0.921	0.000
T50.4 Drugs affecting uric acid metabolism	0.078	0.922	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.078	0.922	0.000
T45.8 Other primarily systemic and haematological agents	0.078	0.922	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.078	0.922	0.000
T45.6 Fibrinolysis-affecting drugs	0.078	0.922	0.000
T45.4 Iron and its compounds	0.078	0.922	0.000
T45.3 Enzymes, not elsewhere classified	0.078	0.922	0.000
T45.2 Vitamins, not elsewhere classified	0.078	0.922	0.000
T36.9 Systemic antibiotic, unspecified	0.078	0.922	0.000
T36.8 Other systemic antibiotics	0.078	0.922	0.000
T36.7 Antifungal antibiotics, systemically used	0.078	0.922	0.000
T36.6 Rifamycins	0.078	0.922	0.000
T36.5 Aminoglycosides	0.078	0.922	0.000
T36.4 Tetracyclines	0.078	0.922	0.000
T36.3 Macrolides	0.078	0.922	0.000
T36.2 Chloramphenicol group	0.078	0.922	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.078	0.922	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.077	0.923	0.000
T50.8 Diagnostic agents	0.076	0.923	0.000
T50.7 Analeptics and opioid receptor antagonists	0.076	0.923	0.000
T50.5 Appetite depressants	0.076	0.923	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.076	0.923	0.000
T50.1 Loop [high-ceiling] diuretics	0.076	0.923	0.000
T50.0 Mineralocorticoids and their antagonists	0.076	0.923	0.000
T41.5 Therapeutic gases	0.073	0.927	0.000
T41.4 Anaesthetic, unspecified	0.073	0.927	0.000
T41.3 Local anaesthetics	0.073	0.927	0.000
T41.2 Other and unspecified general anaesthetics	0.073	0.927	0.000
T41.1 Intravenous anaesthetics	0.073	0.927	0.000
T41.0 Inhaled anaesthetics	0.073	0.927	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.073	0.927	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.073	0.927	0.000
T48.5 Anti-common-cold drugs	0.073	0.927	0.000
T48.4 Expectorants	0.073	0.927	0.000
T48.3 Antitussives	0.073	0.927	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.073	0.927	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.073	0.927	0.000
T48.0 Oxytocic drugs	0.073	0.927	0.000
T49.9 Topical agent, unspecified	0.073	0.927	0.000
T49.8 Other topical agents	0.073	0.927	0.000
T49.7 Dental drugs, topically applied	0.073	0.927	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.073	0.927	0.000
T49.5 Ophthalmological drugs and preparations	0.073	0.927	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.073	0.927	0.000
T49.3 Emollients, demulcents and protectants	0.073	0.927	0.000
T49.2 Local astringents and local detergents	0.073	0.927	0.000
T49.1 Antipruritics	0.073	0.927	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.073	0.927	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.072	0.928	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.071	0.929	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.070	0.930	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.068	0.932	0.000
T45.5 Anticoagulants	0.066	0.934	0.000
T39.4 Antirheumatics, not elsewhere classified	0.064	0.936	0.000
T39.2 Pyrazolone derivatives	0.064	0.936	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.064	0.936	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.058	0.942	0.000
T39.1 4-Aminophenol derivatives	0.053	0.947	0.000
D12.4 Descending colon	0.052	0.948	0.000
K82.8 Other specified diseases of gallbladder	0.048	0.952	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.041	0.959	0.000
T39.0 Salicylates	0.037	0.963	0.000
Z22.3 Carrier of other specified bacterial diseases	0.017	0.983	0.000
G62.8 Other specified polyneuropathies	0.014	0.986	0.000
K82 Other diseases of gallbladder	0.010	0.990	0.000
Z22 Carrier of infectious disease	0.009	0.991	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.009	0.991	0.000
G62 Other polyneuropathies	0.009	0.991	0.000
K82.2 Perforation of gallbladder	0.008	0.991	0.000
Z22.5 Carrier of viral hepatitis	0.008	0.992	0.000
K82.3 Fistula of gallbladder	0.008	0.992	0.000
K82.0 Obstruction of gallbladder	0.007	0.993	0.000
Z22.9 Carrier of infectious disease, unspecified	0.007	0.993	0.000
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.007	0.993	0.000
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.007	0.993	0.000
Z22.2 Carrier of diphtheria	0.007	0.993	0.000
Z22.0 Carrier of typhoid	0.007	0.993	0.000
Z22.1 Carrier of other intestinal infectious diseases	0.007	0.993	0.000
G61.8 Other inflammatory polyneuropathies	0.007	0.993	0.000
G62.9 Polyneuropathy, unspecified	0.007	0.993	0.000
G62.2 Polyneuropathy due to other toxic agents	0.007	0.993	0.000
K82.1 Hydrops of gallbladder	0.007	0.993	0.000
G62.0 Drug-induced polyneuropathy	0.006	0.993	0.000
G61 Inflammatory polyneuropathy	0.006	0.994	0.000
Z22.8 Carrier of other infectious diseases	0.006	0.994	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.006	0.994	0.000
G62.1 Alcoholic polyneuropathy	0.006	0.994	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.005	0.995	0.000
K82.9 Disease of gallbladder, unspecified	0.005	0.995	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.005	0.995	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.005	0.995	0.000
G61.1 Serum neuropathy	0.005	0.995	0.000
G63.2 Diabetic polyneuropathy	0.005	0.995	0.000
G64 Other disorders of peripheral nervous system	0.005	0.995	0.000
G61.0 Guillain-Barre syndrome	0.004	0.996	0.000
D86.9 Sarcoidosis, unspecified	0.004	0.996	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.004	0.996	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.004	0.996	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.004	0.996	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.004	0.996	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.004	0.996	0.000
G63.1 Polyneuropathy in neoplastic disease	0.004	0.996	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
K82.4 Cholesterolosis of gallbladder	0.004	0.996	0.000
M25.74 Osteophyte (Hand)	0.003	0.997	0.000
H35.0 Background retinopathy and retinal vascular changes	0.003	0.997	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.997	0.003
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997	0.000
M23.49 Loose body in knee-Unspec lig/men	0.003	0.997	0.000
M34.9 Systemic sclerosis, unspecified	0.000	0.997	0.003
G60 Hereditary and idiopathic neuropathy	0.002	0.997	0.001
D86 Sarcoidosis	0.003	0.997	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.000	0.997	0.003
T18.1 Foreign body in oesophagus	0.000	0.997	0.003
N20.1 Calculus of ureter	0.000	0.997	0.003
E89.0 Postprocedural hypothyroidism	0.003	0.997	0.000
S43.0 Dislocation of shoulder joint	0.000	0.997	0.003
C32.9 Larynx, unspecified	0.000	0.997	0.003
C32.0 Glottis	0.000	0.997	0.003
D66 Hereditary factor VIII deficiency	0.003	0.997	0.000
D86.8 Sarcoidosis of other and combined sites	0.003	0.997	0.000
K04.5 Chronic apical periodontitis	0.000	0.997	0.003
O36.8 Maternal care for other specified foetal problems	0.003	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.003	0.997	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.997	0.000
M34.8 Other forms of systemic sclerosis	0.000	0.997	0.003
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.000	0.997	0.003
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.002	0.997	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.002	0.998	0.001
G60.3 Idiopathic progressive neuropathy	0.002	0.998	0.001
G60.2 Neuropathy in association with hereditary ataxia	0.002	0.998	0.001
G60.1 Refsum's disease	0.002	0.998	0.001
C32 Malignant neoplasm of larynx	0.000	0.998	0.002
M54.50 Low back pain (Multiple sites in spine)	0.000	0.998	0.002
Y57.9 Drug or medicament, unspecified	0.000	0.998	0.002
T18.9 Foreign body in alimentary tract, part unspecified	0.000	0.998	0.002
M34 Systemic sclerosis	0.000	0.998	0.002
W49.9 Unspecified place	0.002	0.998	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.998	0.002
C32.1 Supraglottis	0.000	0.998	0.002
S27.0 Traumatic pneumothorax	0.002	0.998	0.000
M25.53 Pain in joint (Forearm)	0.000	0.998	0.002
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
M34.1 CR(E)ST syndrome	0.000	0.998	0.002
K61.3 Ischiorectal abscess	0.000	0.998	0.002
B00.9 Herpesviral infection, unspecified	0.000	0.998	0.002
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
M25.72 Osteophyte (Upper arm)	0.002	0.998	0.000
T18 Foreign body in alimentary tract	0.000	0.998	0.002
G60.8 Other hereditary and idiopathic neuropathies	0.001	0.998	0.001
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.002	0.998	0.000
C32.8 Overlapping lesion of larynx	0.000	0.998	0.002
C32.3 Laryngeal cartilage	0.000	0.998	0.002
C32.2 Subglottis	0.000	0.998	0.002
Z29.2 Other prophylactic chemotherapy	0.000	0.998	0.002
M93.9 Osteochondropathy, unspecified	0.000	0.998	0.002
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.998	0.002
M34.0 Progressive systemic sclerosis	0.000	0.998	0.002
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
G60.0 Hereditary motor and sensory neuropathy	0.001	0.998	0.001
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
S27 Injury of other and unspecified intrathoracic organs	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
J39.8 Other specified diseases of upper respiratory tract	0.002	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.002	0.998	0.000
Z82.3 Family history of stroke	0.002	0.998	0.000
B01.9 Varicella without complications	0.000	0.998	0.002
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.000	0.998	0.002
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
S21.9 Open wound of thorax, part unspecified	0.002	0.998	0.000
Z51.4 Preparatory care for treatment, not elsewhere classified	0.002	0.998	0.000
S27.3 Other injuries of lung	0.002	0.998	0.000
T18.8 Foreign body in other and multiple parts of alimentary tract	0.000	0.998	0.002
T18.4 Foreign body in colon	0.000	0.998	0.002
T18.3 Foreign body in small intestine	0.000	0.998	0.002
T18.2 Foreign body in stomach	0.000	0.998	0.002
T18.0 Foreign body in mouth	0.000	0.998	0.002
C34.3 Lower lobe, bronchus or lung	0.000	0.998	0.002
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.000	0.998	0.002
S27.1 Traumatic haemothorax	0.002	0.998	0.000
X60.8 Other specified place	0.002	0.998	0.000
B00 Herpesviral [herpes simplex] infections	0.000	0.998	0.002
B00.4 Herpesviral encephalitis	0.000	0.998	0.002
Z11.5 Special screening examination for other viral diseases	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
S21 Open wound of thorax	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.002	0.998	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.002	0.998	0.000
S27.9 Injury of unspecified intrathoracic organ	0.002	0.998	0.000
S27.7 Multiple injuries of intrathoracic organs	0.002	0.998	0.000
S27.6 Injury of pleura	0.002	0.998	0.000
S27.5 Injury of thoracic trachea	0.002	0.998	0.000
S27.4 Injury of bronchus	0.002	0.998	0.000
C01 Malignant neoplasm of base of tongue	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.002	0.998	0.000
C90.0 Multiple myeloma	0.000	0.998	0.002
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.998	0.002
F12.1 Harmful use	0.002	0.998	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.002	0.998	0.000
M23.4 Loose body in knee	0.002	0.998	0.000
S27.8 Injury of other specified intrathoracic organs	0.001	0.998	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.002	0.998	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.998	0.002
R19.5 Other fecal abnormalities	0.000	0.998	0.002
Z24 Need for immunisation against certain single viral diseases	0.001	0.998	0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.000	0.998	0.002
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.002	0.998	0.000
Z28 Immunisation not carried out	0.001	0.998	0.000
Z27 Need for immunisation against combinations of infectious diseases	0.001	0.998	0.000
Z26 Need for immunisation against other single infectious diseases	0.001	0.998	0.000
Z25 Need for immunisation against other single viral diseases	0.001	0.998	0.000
Z23 Need for immunisation against single bacterial diseases	0.001	0.998	0.000
Z20 Contact with and exposure to communicable diseases	0.001	0.998	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.001	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.001	0.998	0.000
S21.1 Open wound of front wall of thorax	0.001	0.998	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.000	0.998	0.002
T18.5 Foreign body in anus and rectum	0.000	0.998	0.001
Z11.8 Special screening examination for other infectious and parasitic diseases	0.001	0.998	0.000
Z11.2 Special screening examination for other bacterial diseases	0.002	0.998	0.000
S29.8 Other specified injuries of thorax	0.001	0.998	0.000
S29 Other and unspecified injuries of thorax	0.002	0.998	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.001	0.998	0.000
H53.4 Visual field defects	0.002	0.998	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.001	0.998	0.000
B00.7 Disseminated herpesviral disease	0.000	0.998	0.001
B00.3 Herpesviral meningitis	0.000	0.998	0.001
B00.1 Herpesviral vesicular dermatitis	0.000	0.998	0.001
B00.0 Eczema herpeticum	0.000	0.998	0.001
S27.2 Traumatic heamopneumothorax	0.001	0.998	0.000
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified	0.001	0.998	0.000
S43.1 Dislocation of acromioclavicular joint	0.000	0.998	0.001
S60.0 Contusion of finger(s) without damage to nail	0.001	0.998	0.000
S20-S29 Injuries to the thorax	0.002	0.998	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.000	0.998	0.001
B00.5 Herpesviral ocular disease	0.000	0.998	0.001
S21.8 Open wound of other parts of thorax	0.001	0.998	0.000
S21.7 Multiple open wounds of thoracic wall	0.001	0.998	0.000
S21.2 Open wound of back wall of thorax	0.001	0.998	0.000
S21.0 Open wound of breast	0.001	0.998	0.000
D84 Other immunodeficiencies	0.001	0.999	0.000
D82 Immunodeficiency associated with other major defects	0.001	0.999	0.000
D81 Combined immunodeficiencies	0.001	0.999	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.001	0.999	0.000
Z24.5 Need for immunisation against rubella alone	0.001	0.999	0.000
D83 Common variable immunodeficiency	0.001	0.999	0.000
M23.47 Loose body in knee-Capsular lig	0.001	0.999	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.001	0.999	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.001	0.999	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.001	0.999	0.000
M23.40 Loose body in knee-Mult sites	0.001	0.999	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.001	0.999	0.000
B00.8 Other forms of herpesviral infection	0.000	0.999	0.001
K38.8 Other specified diseases of appendix	0.000	0.999	0.001
Z11.6 Special screening examination for other protozoal diseases and helminthiases	0.001	0.999	0.000
Z11.3 Special screening examination for infections with a predominantly sexual mode of transmission	0.001	0.999	0.000
Z11.1 Special screening examination for respiratory tuberculosis	0.001	0.999	0.000
Z24.6 Need for immunisation against viral hepatitis	0.001	0.999	0.000
Z24.4 Need for immunisation against measles alone	0.001	0.999	0.000
Z24.3 Need for immunisation against yellow fever	0.001	0.999	0.000
Z24.2 Need for immunisation against rabies	0.001	0.999	0.000
Z24.1 Need for immunisation against arthropod-borne viral encephalitis	0.001	0.999	0.000
Z24.0 Need for immunisation against poliomyelitis	0.001	0.999	0.000
S29.9 Unspecified injury of thorax	0.001	0.999	0.000
Z20.9 Contact with and exposure to unspecified communicable disease	0.001	0.999	0.000
Z20.7 Contact with and exposure to pediculosis, acariasis and other infestations	0.001	0.999	0.000
Z20.6 Contact with and exposure to human immunodeficiency virus [HIV]	0.001	0.999	0.000
Z20.5 Contact with and exposure to viral hepatitis	0.001	0.999	0.000
Z20.4 Contact with and exposure to rubella	0.001	0.999	0.000
Z20.3 Contact with and exposure to rabies	0.001	0.999	0.000
Z20.2 Contact with and exposure to infections with a predominantly sexual mode of transmission	0.001	0.999	0.000
Z20.1 Contact with and exposure to tuberculosis	0.001	0.999	0.000
Z20.0 Contact with and exposure to intestinal infectious diseases	0.001	0.999	0.000
Z23.8 Need for immunisation against other single bacterial diseases	0.001	0.999	0.000
Z23.7 Need for immunisation against pertussis alone	0.001	0.999	0.000
Z23.6 Need for immunisation against diphtheria alone	0.001	0.999	0.000
Z23.5 Need for immunisation against tetanus alone	0.001	0.999	0.000
Z23.4 Need for immunisation against tularaemia	0.001	0.999	0.000
Z23.3 Need for immunisation against plague	0.001	0.999	0.000
Z23.2 Need for immunisation against tuberculosis [BCG]	0.001	0.999	0.000
Z23.1 Need for immunisation against typhoid-paratyphoid alone [TAB]	0.001	0.999	0.000
Z23.0 Need for immunisation against cholera alone	0.001	0.999	0.000
Z25.8 Need for immunisation against other specified single viral diseases	0.001	0.999	0.000
Z25.1 Need for immunisation against influenza	0.001	0.999	0.000
Z25.0 Need for immunisation against mumps alone	0.001	0.999	0.000
Z26.9 Need for immunisation against unspecified infectious disease	0.001	0.999	0.000
Z26.8 Need for immunisation against other specified single infectious diseases	0.001	0.999	0.000
Z26.0 Need for immunisation against leishmaniasis	0.001	0.999	0.000
Z27.9 Need for immunisation against unspecified combinations of infectious diseases	0.001	0.999	0.000
Z27.8 Need for immunisation against other combinations of infectious diseases	0.001	0.999	0.000
Z27.4 Need for immunisation against measles-mumps-rubella [MMR]	0.001	0.999	0.000
Z27.3 Need for immunisation against diphtheria-tetanus-pertussis with poliomyelitis [DTP + polio]	0.001	0.999	0.000
Z27.2 Need for immunisation against diphtheria-tetanus-pertussis with typhoid-paratyphoid [DTP + TAB]	0.001	0.999	0.000
Z27.1 Need for immunisation against diphtheria-tetanus-pertussis, combined [DTP]	0.001	0.999	0.000
Z27.0 Need for immunisation against cholera with typhoid-paratyphoid [cholera + TAB]	0.001	0.999	0.000
Z28.9 Immunisation not carried out for unspecified reason	0.001	0.999	0.000
Z28.8 Immunisation not carried out for other reasons	0.001	0.999	0.000
Z28.2 Immunisation not carried out because of patient's decision for other and unspecified reasons	0.001	0.999	0.000
Z28.1 Immunisation not carried out because of patient's decision for reasons of belief or group pressure	0.001	0.999	0.000
Z28.0 Immunisation not carried out because of contraindication	0.001	0.999	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.001	0.999	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.000	0.999	0.001
S43.6 Sprain and strain of sternoclavicular joint	0.000	0.999	0.001
S43.4 Sprain and strain of shoulder joint	0.000	0.999	0.001
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.000	0.999	0.001
S43.2 Dislocation of sternoclavicular joint	0.000	0.999	0.001
X60.2 School, other institution and public administrative area	0.001	0.999	0.000
Z20.8 Contact with and exposure to other communicable diseases	0.001	0.999	0.000
B01 Varicella [chickenpox]	0.000	0.999	0.001
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.001	0.999	0.000
S29.7 Multiple injuries of thorax	0.001	0.999	0.000
S29.0 Injury of muscle and tendon at thorax level	0.001	0.999	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.000	0.999	0.001
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.000	0.999	0.001
D84.8 Other specified immunodeficiencies	0.001	0.999	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
E89.3 Postprocedural hypopituitarism	0.001	0.999	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.999	0.001
S20.3 Other superficial injuries of front wall of thorax	0.001	0.999	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.001	0.999	0.000
S26 Injury of heart	0.001	0.999	0.000
S25 Injury of blood vessels of thorax	0.001	0.999	0.000
S24 Injury of nerves and spinal cord at thorax level	0.001	0.999	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.001	0.999	0.000
M23.46 Loose body in knee-O/unsp lat men	0.001	0.999	0.000
D81.9 Combined immunodeficiency, unspecified	0.001	0.999	0.000
D81.8 Other combined immunodeficiencies	0.001	0.999	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.999	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.999	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.999	0.000
D81.4 Nezelof's syndrome	0.001	0.999	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.999	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.999	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.999	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.999	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.999	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.999	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.999	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.999	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.999	0.000
D82.1 Di George's syndrome	0.001	0.999	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.999	0.000
D84.1 Defects in the complement system	0.001	0.999	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.999	0.000
Q76.0 Spina bifida occulta	0.000	0.999	0.001
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.001	0.999	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.999	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.999	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.999	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.999	0.000
D83.9 Common variable immunodeficiency, unspecified	0.001	0.999	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.000	0.999	0.001
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.999	0.001
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.001	0.999	0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.001	0.999	0.000
S22.50 Flail chest (closed)	0.001	0.999	0.000
A63.0 Anogenital (venereal) warts	0.001	0.999	0.000
B01.8 Varicella with other complications	0.000	0.999	0.001
B01.2 Varicella pneumonia	0.000	0.999	0.001
B01.1 Varicella encephalitis	0.000	0.999	0.001
B01.0 Varicella meningitis	0.000	0.999	0.001
M54.5 Low back pain	0.000	0.999	0.001
S60.9 Superficial injury of wrist and hand, unspecified	0.001	0.999	0.000
W49.8 Other specified place	0.001	0.999	0.000
W49.7 Farm	0.001	0.999	0.000
W49.5 Trade and service area	0.001	0.999	0.000
W49.4 Street and highway	0.001	0.999	0.000
W49.3 Sports and athletics area	0.001	0.999	0.000
W49.2 School, other institution and public administrative area	0.001	0.999	0.000
W49.1 Residential institution	0.001	0.999	0.000
S20 Superficial injury of thorax	0.001	0.999	0.000
D84.9 Immunodeficiency, unspecified	0.001	0.999	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.001	0.999	0.000
I44.0 Atrioventricular block, first degree	0.001	0.999	0.000
W29.9 Unspecified place	0.001	0.999	0.000
W49.6 Industrial and construction area	0.001	0.999	0.000
Z29.0 Isolation	0.001	0.999	0.000
Z29 Need for other prophylactic measures	0.001	0.999	0.001
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.001	0.999	0.000
M23.43 Loose body in knee-Med lig/oth men	0.001	0.999	0.000
D89.1 Cryoglobulinaemia	0.001	0.999	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.001	0.999	0.000
S23.4 Sprain and strain of ribs and sternum	0.001	0.999	0.000
S23.3 Sprain and strain of thoracic spine	0.001	0.999	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.001	0.999	0.000
S23.1 Dislocation of thoracic vertebra	0.001	0.999	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations