TreeWAS – Variant ID: rs698833

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T39.1 4-Aminophenol derivatives	0.051	0.949	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.051	0.949	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.049	0.951	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.048	0.952	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.047	0.953	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.045	0.955	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.044	0.956	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.044	0.956	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.043	0.957	0.000
T42.4 Benzodiazepines	0.042	0.958	0.000
T36 Poisoning by systemic antibiotics	0.042	0.958	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.042	0.958	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.041	0.959	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.040	0.960	0.000
T39.0 Salicylates	0.039	0.961	0.000
T43.2 Other and unspecified antidepressants	0.038	0.962	0.000
T43.6 Psychostimulants with abuse potential	0.038	0.962	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.038	0.962	0.000
T36.0 Penicillins	0.038	0.962	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.037	0.962	0.000
T39.4 Antirheumatics, not elsewhere classified	0.037	0.963	0.000
T39.2 Pyrazolone derivatives	0.037	0.963	0.000
T46.1 Calcium-channel blockers	0.037	0.963	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.037	0.963	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.037	0.963	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.036	0.964	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.036	0.964	0.000
C79 Secondary malignant neoplasm of other sites	0.036	0.964	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.035	0.965	0.000
T42.1 Iminostilbenes	0.035	0.965	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.035	0.965	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.035	0.965	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.035	0.965	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.034	0.966	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.034	0.966	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.034	0.966	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.033	0.966	0.000
T42.2 Succinimides and oxazolidinediones	0.033	0.966	0.000
C79.2 Secondary malignant neoplasm of skin	0.033	0.967	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.033	0.967	0.000
T43.9 Psychotropic drug, unspecified	0.032	0.967	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.032	0.968	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.032	0.968	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.032	0.968	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.031	0.968	0.000
T42.0 Hydantoin derivatives	0.031	0.969	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.031	0.969	0.000
T46.7 Peripheral vasodilators	0.031	0.969	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.031	0.969	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.031	0.969	0.000
T36.4 Tetracyclines	0.030	0.969	0.000
T36.9 Systemic antibiotic, unspecified	0.030	0.970	0.000
T36.8 Other systemic antibiotics	0.030	0.970	0.000
T36.7 Antifungal antibiotics, systemically used	0.030	0.970	0.000
T36.6 Rifamycins	0.030	0.970	0.000
T36.5 Aminoglycosides	0.030	0.970	0.000
T36.2 Chloramphenicol group	0.030	0.970	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.030	0.970	0.000
T42.3 Barbiturates	0.029	0.970	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.029	0.971	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.029	0.971	0.000
T36.3 Macrolides	0.029	0.971	0.000
T48.5 Anti-common-cold drugs	0.028	0.972	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.028	0.972	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.028	0.972	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.028	0.972	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.027	0.973	0.000
T48.4 Expectorants	0.027	0.973	0.000
T48.3 Antitussives	0.027	0.973	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.027	0.973	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.027	0.973	0.000
T48.0 Oxytocic drugs	0.027	0.973	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.027	0.973	0.000
T37.5 Antiviral drugs	0.027	0.973	0.000
T37.4 Anthelminthics	0.027	0.973	0.000
T37.3 Other antiprotozoal drugs	0.027	0.973	0.000
T37.1 Antimycobacterial drugs	0.027	0.973	0.000
T37.0 Sulphonamides	0.027	0.973	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.027	0.973	0.000
T47.2 Stimulant laxatives	0.027	0.973	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.027	0.973	0.000
T47.4 Other laxatives	0.027	0.973	0.000
T50.4 Drugs affecting uric acid metabolism	0.027	0.973	0.000
T50.1 Loop [high-ceiling] diuretics	0.026	0.973	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.026	0.973	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.026	0.974	0.000
T38.9 Other and unspecified hormone antagonists	0.026	0.974	0.000
T38.7 Androgens and anabolic congeners	0.026	0.974	0.000
T38.4 Oral contraceptives	0.026	0.974	0.000
T38.2 Antithyroid drugs	0.026	0.974	0.000
T38.0 Glucocorticoids and synthetic analogues	0.025	0.974	0.000
T41.5 Therapeutic gases	0.025	0.974	0.000
T41.4 Anaesthetic, unspecified	0.025	0.974	0.000
T41.3 Local anaesthetics	0.025	0.974	0.000
T41.2 Other and unspecified general anaesthetics	0.025	0.974	0.000
T41.1 Intravenous anaesthetics	0.025	0.974	0.000
T41.0 Inhaled anaesthetics	0.025	0.974	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.025	0.974	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.025	0.975	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.025	0.975	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.025	0.975	0.000
T47.7 Emetics	0.025	0.975	0.000
T47.5 Digestants	0.025	0.975	0.000
T47.3 Saline and osmotic laxatives	0.025	0.975	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.025	0.975	0.000
T38.5 Other oestrogens and progestogens	0.025	0.975	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.025	0.975	0.000
T50.7 Analeptics and opioid receptor antagonists	0.025	0.975	0.000
T50.5 Appetite depressants	0.025	0.975	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.025	0.975	0.000
T50.0 Mineralocorticoids and their antagonists	0.025	0.975	0.000
T47.6 Antidiarrhoeal drugs	0.025	0.975	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.024	0.976	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.024	0.976	0.000
T40.4 Other synthetic narcotics	0.023	0.977	0.000
T49.9 Topical agent, unspecified	0.023	0.977	0.000
T49.8 Other topical agents	0.023	0.977	0.000
T49.7 Dental drugs, topically applied	0.023	0.977	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.023	0.977	0.000
T49.5 Ophthalmological drugs and preparations	0.023	0.977	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.023	0.977	0.000
T49.3 Emollients, demulcents and protectants	0.023	0.977	0.000
T49.2 Local astringents and local detergents	0.023	0.977	0.000
T49.1 Antipruritics	0.023	0.977	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.023	0.977	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.977	0.023
C79.9 Secondary malignant neoplasm, unspecified site	0.023	0.977	0.000
T50.8 Diagnostic agents	0.022	0.977	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.022	0.978	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.978	0.022
C79.6 Secondary malignant neoplasm of ovary	0.022	0.978	0.000
T47.0 Histamine H(2)-receptor antagonists	0.021	0.979	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.021	0.979	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.979	0.021
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.020	0.980	0.000
T45.2 Vitamins, not elsewhere classified	0.020	0.980	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.020	0.980	0.000
T38.1 Thyroid hormones and substitutes	0.019	0.980	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.019	0.980	0.000
T40.8 Lysergide [LSD]	0.019	0.980	0.000
T40.7 Cannabis (derivatives)	0.019	0.980	0.000
T40.0 Opium	0.019	0.980	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.019	0.981	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.019	0.981	0.000
T40.6 Other and unspecified narcotics	0.018	0.981	0.000
T45.4 Iron and its compounds	0.018	0.981	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.018	0.982	0.000
O34.4 Maternal care for other abnormalities of cervix	0.018	0.982	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.018	0.982	0.000
T45.8 Other primarily systemic and haematological agents	0.018	0.982	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.018	0.982	0.000
T45.6 Fibrinolysis-affecting drugs	0.018	0.982	0.000
T45.3 Enzymes, not elsewhere classified	0.018	0.982	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.982	0.018
T40.3 Methadone	0.018	0.982	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.017	0.982	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.017	0.982	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.017	0.982	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.017	0.982	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.017	0.982	0.000
T44.0 Anticholinesterase agents	0.017	0.982	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.017	0.983	0.000
T40.1 Heroin	0.017	0.983	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.000	0.983	0.017
T40.5 Cocaine	0.016	0.984	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.016	0.984	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.015	0.984	0.000
T45.0 Antiallergic and antiemetic drugs	0.015	0.984	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.985	0.015
T40.2 Other opioids	0.015	0.985	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.015	0.985	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.985	0.015
T45.1 Antineoplastic and immunosuppressive drugs	0.015	0.985	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.985	0.014
N18.5 Chronic kidney disease, stage 5	0.000	0.986	0.014
O34.6 Maternal care for abnormality of vagina	0.014	0.986	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.986	0.014
S66.8 Injury of other muscles and tendons at wrist and hand level	0.000	0.986	0.014
O34.5 Maternal care for other abnormalities of gravid uterus	0.014	0.986	0.000
T45.5 Anticoagulants	0.013	0.986	0.000
O34.0 Maternal care for congenital malformation of uterus	0.014	0.986	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.013	0.986	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.987	0.013
O34.1 Maternal care for tumour of corpus uteri	0.013	0.987	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.988	0.012
E27.1 Primary adrenocortical insufficiency	0.000	0.989	0.011
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.011	0.989	0.000
E27 Other disorders of adrenal gland	0.000	0.990	0.010
O34.3 Maternal care for cervical incompetence	0.009	0.991	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.008	0.991	0.000
S02.10 Fracture of base of skull (closed)	0.008	0.992	0.000
Z57.2 Occupational exposure to dust	0.008	0.992	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.993	0.007
E27.5 Adrenomedullary hyperfunction	0.000	0.993	0.007
E27.0 Other adrenocortical overactivity	0.000	0.993	0.007
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
S42.20 Fracture of upper end of humerus (closed)	0.007	0.993	0.000
Z57 Occupational exposure to risk-factors	0.007	0.993	0.000
O03.4 Incomplete, without complication	0.007	0.993	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.993	0.006
M50.2 Other cervical disk displacement	0.006	0.994	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.006	0.994	0.000
K11.5 Sialolithiasis	0.000	0.994	0.006
Z57.3 Occupational exposure to other air contaminants	0.006	0.994	0.000
O03 Spontaneous abortion	0.006	0.994	0.000
R73.0 Abnormal glucose tolerance test	0.006	0.994	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.006	0.994	0.000
O03.9 Complete or unspecified, without complication	0.006	0.994	0.000
E27.2 Addisonian crisis	0.000	0.994	0.005
D86.0 Sarcoidosis of lung	0.006	0.994	0.000
D86 Sarcoidosis	0.006	0.994	0.000
Z29.2 Other prophylactic chemotherapy	0.006	0.994	0.000
Z56 Problems related to employment and unemployment	0.006	0.994	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.994	0.005
D86.9 Sarcoidosis, unspecified	0.005	0.995	0.000
Z63 Other problems related to primary support group, including family circumstances	0.005	0.995	0.000
H20.9 Iridocyclitis, unspecified	0.000	0.995	0.005
N20.1 Calculus of ureter	0.005	0.995	0.000
Z63.7 Other stressful life events affecting family and household	0.005	0.995	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.005	0.995	0.000
Z57.7 Occupational exposure to vibration	0.005	0.995	0.000
Z57.6 Occupational exposure to extreme temperature	0.005	0.995	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.005	0.995	0.000
Z57.1 Occupational exposure to radiation	0.005	0.995	0.000
Z57.0 Occupational exposure to noise	0.005	0.995	0.000
K80.4 Calculus of bile duct with cholecystitis	0.005	0.995	0.000
Z64 Problems related to certain psychosocial circumstances	0.005	0.995	0.000
D86.3 Sarcoidosis of skin	0.005	0.995	0.000
E24 Cushing's syndrome	0.000	0.995	0.005
Z58 Problems related to physical environment	0.005	0.995	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.005	0.995	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.995	0.005
N20.0 Calculus of kidney	0.005	0.995	0.000
K80 Cholelithiasis	0.005	0.995	0.000
Z65 Problems related to other psychosocial circumstances	0.005	0.995	0.000
Z56.6 Other physical and mental strain related to work	0.005	0.995	0.000
D27 Benign neoplasm of ovary	0.005	0.995	0.000
Z29.1 Prophylactic immunotherapy	0.005	0.995	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O03.3 Incomplete, with other and unspecified complications	0.005	0.995	0.000
D86.8 Sarcoidosis of other and combined sites	0.005	0.995	0.000
Z56.4 Discord with boss and workmates	0.005	0.995	0.000
Z64.0 Problems related to unwanted pregnancy	0.005	0.995	0.000
Z62 Other problems related to upbringing	0.004	0.995	0.000
Z55 Problems related to education and literacy	0.004	0.995	0.000
E28.3 Primary ovarian failure	0.000	0.995	0.005
E34 Other endocrine disorders	0.000	0.995	0.005
D86.1 Sarcoidosis of lymph nodes	0.005	0.995	0.000
E34.8 Other specified endocrine disorders	0.000	0.995	0.005
A63.0 Anogenital (venereal) warts	0.000	0.995	0.005
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
Z59 Problems related to housing and economic circumstances	0.004	0.995	0.000
H20.8 Other iridocyclitis	0.000	0.995	0.004
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.004	0.995	0.000
E24.0 Pituitary-dependent Cushing's disease	0.000	0.995	0.004
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
Z60 Problems related to social environment	0.004	0.995	0.000
Z58.5 Exposure to other pollution	0.004	0.996	0.000
O03.7 Complete or unspecified, complicated by embolism	0.004	0.996	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.004	0.996	0.000
O03.2 Incomplete, complicated by embolism	0.004	0.996	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.004	0.996	0.000
Z63.4 Disappearance and death of family member	0.004	0.996	0.000
E28 Ovarian dysfunction	0.000	0.996	0.004
E24.9 Cushing's syndrome, unspecified	0.000	0.996	0.004
Z56.7 Other and unspecified problems related to employment	0.004	0.996	0.000
H20 Iridocyclitis	0.000	0.996	0.004
O03.8 Complete or unspecified, with other and unspecified complications	0.004	0.996	0.000
Z56.0 Unemployment, unspecified	0.004	0.996	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.004	0.996	0.000
Z63.6 Dependent relative needing care at home	0.004	0.996	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.004	0.996	0.000
Z57.8 Occupational exposure to other risk-factors	0.004	0.996	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.004	0.996	0.000
E24.8 Other Cushing's syndrome	0.000	0.996	0.004
E24.2 Drug-induced Cushing's syndrome	0.000	0.996	0.004
Z56.5 Uncongenial work	0.004	0.996	0.000
Z56.2 Threat of job loss	0.004	0.996	0.000
Z56.1 Change of job	0.004	0.996	0.000
Z29 Need for other prophylactic measures	0.004	0.996	0.000
N20 Calculus of kidney and ureter	0.004	0.996	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.004	0.996	0.000
Z56.3 Stressful work schedule	0.004	0.996	0.000
Z63.9 Problem related to primary support group, unspecified	0.004	0.996	0.000
Z63.3 Absence of family member	0.004	0.996	0.000
Z63.2 Inadequate family support	0.004	0.996	0.000
Z63.1 Problems in relationship with parents and in-laws	0.004	0.996	0.000
Z61 Problems related to negative life events in childhood	0.004	0.996	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.004	0.996	0.000
Z64.4 Discord with counsellors	0.004	0.996	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.004	0.996	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.004	0.996	0.000
Z64.1 Problems related to multiparity	0.004	0.996	0.000
Z65.3 Problems related to other legal circumstances	0.004	0.996	0.000
M50 Cervical disk disorders	0.004	0.996	0.000
Z63.5 Disruption of family by separation and divorce	0.004	0.996	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.996	0.004
E24.3 Ectopic ACTH syndrome	0.000	0.996	0.004
E24.1 Nelson's syndrome	0.000	0.996	0.004
Z63.8 Other specified problems related to primary support group	0.004	0.996	0.000
Z58.9 Problem related to physical environment, unspecified	0.004	0.996	0.000
Z58.6 Inadequate drinking-water supply	0.004	0.996	0.000
Z58.4 Exposure to radiation	0.004	0.996	0.000
Z58.3 Exposure to soil pollution	0.004	0.996	0.000
Z58.2 Exposure to water pollution	0.004	0.996	0.000
Z58.0 Exposure to noise	0.004	0.996	0.000
E25 Adrenogenital disorders	0.000	0.996	0.004
Z58.7 Exposure to tobacco smoke	0.004	0.996	0.000
Z58.8 Other problems related to physical environment	0.004	0.996	0.000
E29 Testicular dysfunction	0.000	0.996	0.004
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.996	0.004
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.996	0.004
E30 Disorders of puberty, not elsewhere classified	0.000	0.996	0.004
H20.0 Acute and subacute iridocyclitis	0.000	0.996	0.004
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
Z58.1 Exposure to air pollution	0.004	0.996	0.000
K80.3 Calculus of bile duct with cholangitis	0.004	0.996	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.000	0.996	0.004
Z60.9 Problem related to social environment, unspecified	0.004	0.996	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.004	0.996	0.000
Z65.4 Victim of crime and terrorism	0.004	0.996	0.000
Z65.2 Problems related to release from prison	0.004	0.996	0.000
Z65.1 Imprisonment and other incarceration	0.004	0.996	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.004	0.996	0.000
Z60.8 Other problems related to social environment	0.004	0.996	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.004	0.996	0.000
M50.0 Cervical disk disorder with myelopathy	0.004	0.996	0.000
E31 Polyglandular dysfunction	0.000	0.996	0.004
R27.0 Ataxia, unspecified	0.000	0.996	0.004
S42.2 Fracture of upper end of humerus	0.004	0.996	0.000
Z59.0 Homelessness	0.004	0.996	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
U80.1 Methicillin resistant agent	0.004	0.996	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.996	0.004
E34.9 Endocrine disorder, unspecified	0.000	0.996	0.004
M50.9 Cervical disk disorder, unspecified	0.004	0.996	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.003	0.996	0.000
Z55.8 Other problems relating to education and literacy	0.003	0.996	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.003	0.996	0.000
Z55.3 Underachievement in school	0.003	0.996	0.000
Z55.2 Failed examinations	0.003	0.996	0.000
Z55.1 Schooling unavailable and unattainable	0.003	0.996	0.000
Z55.0 Illiteracy and low-level literacy	0.003	0.996	0.000
Z62.9 Problem related to upbringing, unspecified	0.003	0.996	0.000
Z62.8 Other specified problems related to upbringing	0.003	0.996	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.003	0.996	0.000
Z62.5 Other problems related to neglect in upbringing	0.003	0.996	0.000
Z62.4 Emotional neglect of child	0.003	0.996	0.000
Z62.3 Hostility towards and scapegoating of child	0.003	0.996	0.000
Z62.2 Institutional upbringing	0.003	0.996	0.000
Z62.1 Parental overprotection	0.003	0.996	0.000
Z62.0 Inadequate parental supervision and control	0.003	0.996	0.000
E34.5 Androgen resistance syndrome	0.000	0.996	0.003
E34.4 Constitutional tall stature	0.000	0.996	0.003
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.996	0.003
E34.1 Other hypersecretion of intestinal hormones	0.000	0.996	0.003
H50.5 Heterophoria	0.000	0.996	0.004
S02.1 Fracture of base of skull	0.004	0.996	0.000
E32 Diseases of thymus	0.000	0.996	0.003
H50.2 Vertical strabismus	0.000	0.996	0.004
Z65.8 Other specified problems related to psychosocial circumstances	0.003	0.996	0.000
Z59.7 Insufficient social insurance and welfare support	0.003	0.996	0.000
Z59.6 Low income	0.003	0.996	0.000
Z59.5 Extreme poverty	0.003	0.996	0.000
Z59.4 Lack of adequate food	0.003	0.996	0.000
Z59.3 Problems related to living in residential institution	0.003	0.996	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.003	0.996	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.003	0.996	0.000
Z60.4 Social exclusion and rejection	0.003	0.996	0.000
Z60.3 Acculturation difficulty	0.003	0.996	0.000
Z60.1 Atypical parenting situation	0.003	0.996	0.000
Z60.0 Problems of adjustment to life-cycle transitions	0.003	0.996	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.997	0.003
E28.8 Other ovarian dysfunction	0.000	0.997	0.003
E28.1 Androgen excess	0.000	0.997	0.003
E28.0 Oestrogen excess	0.000	0.997	0.003
E34.3 Short stature, not elsewhere classified	0.000	0.997	0.003
H50.1 Divergent concomitant strabismus	0.000	0.997	0.003
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.997	0.003
Z29.8 Other specified prophylactic measures	0.003	0.997	0.000
H20.2 Lens-induced iridocyclitis	0.000	0.997	0.003
K80.8 Other cholelithiasis	0.003	0.997	0.000
N20.9 Urinary calculus, unspecified	0.003	0.997	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
M50.8 Other cervical disk disorders	0.003	0.997	0.000
Z59.1 Inadequate housing	0.003	0.997	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.997	0.003
K80.1 Calculus of gallbladder with other cholecystitis	0.003	0.997	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
Z29.9 Prophylactic measure, unspecified	0.003	0.997	0.000
E20 Hypoparathyroidism	0.000	0.997	0.003
E34.0 Carcinoid syndrome	0.000	0.997	0.003
Z63.0 Problems in relationship with spouse or partner	0.003	0.997	0.000
Z61.9 Negative life events in childhood, unspecified	0.003	0.997	0.000
Z61.7 Personal frightening experience in childhood	0.003	0.997	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.003	0.997	0.000
Z61.2 Altered pattern of family relationships in childhood	0.003	0.997	0.000
Z61.1 Removal from home in childhood	0.003	0.997	0.000
Z61.0 Loss of love relationship in childhood	0.003	0.997	0.000
E26 Hyperaldosteronism	0.000	0.997	0.003
H50 Other strabismus	0.000	0.997	0.003
Z61.8 Other negative life events in childhood	0.003	0.997	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.003	0.997	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.997	0.003
M50.3 Other cervical disk degeneration	0.003	0.997	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.003	0.997	0.000
Z61.6 Problems related to alleged physical abuse of child	0.003	0.997	0.000
H20.1 Chronic iridocyclitis	0.000	0.997	0.003
S42.21 Fracture of upper end of humerus (open)	0.003	0.997	0.000
E25.9 Adrenogenital disorder, unspecified	0.000	0.997	0.003
E25.8 Other adrenogenital disorders	0.000	0.997	0.003
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.003	0.997	0.000
E29.8 Other testicular dysfunction	0.000	0.997	0.003
E29.0 Testicular hyperfunction	0.000	0.997	0.003
E30.9 Disorder of puberty, unspecified	0.000	0.997	0.003
E30.8 Other disorders of puberty	0.000	0.997	0.003
E30.1 Precocious puberty	0.000	0.997	0.003
E30.0 Delayed puberty	0.000	0.997	0.003
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.997	0.003
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.997	0.003
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.997	0.003
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.003	0.997	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.000	0.997	0.003
Z99.2 Dependence on renal dialysis	0.000	0.997	0.003
E31.9 Polyglandular dysfunction, unspecified	0.000	0.997	0.003
E31.8 Other polyglandular dysfunction	0.000	0.997	0.003
E31.1 Polyglandular hyperfunction	0.000	0.997	0.003
I70.2 Atherosclerosis of arteries of the extremities	0.003	0.997	0.000
E32.9 Disease of thymus, unspecified	0.000	0.997	0.003
E32.1 Abscess of thymus	0.000	0.997	0.003
E32.0 Persistent hyperplasia of thymus	0.000	0.997	0.003
H02.6 Xanthelasma of eyelid	0.003	0.997	0.000
M25.50 Pain in joint (Multiple sites)	0.000	0.997	0.003
K80.0 Calculus of gallbladder with acute cholecystitis	0.003	0.997	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.997	0.003
S72.30 Fracture of shaft of femur (closed)	0.003	0.997	0.000
E31.0 Autoimmune polyglandular failure	0.000	0.997	0.003
Y83.3 Surgical operation with formation of external stoma	0.003	0.997	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.997	0.003
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.997	0.003
O00-O08 Pregnancy with abortive outcome	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.000	0.997	0.003
K80.2 Calculus of gallbladder without cholecystitis	0.003	0.997	0.000
S68 Traumatic amputation of wrist and hand	0.000	0.997	0.003
E20.1 Pseudohypoparathyroidism	0.000	0.997	0.002
E20.0 Idiopathic hypoparathyroidism	0.000	0.997	0.002
E28.2 Polycystic ovarian syndrome	0.000	0.997	0.003
H81.0 Meniere's disease	0.000	0.997	0.003
N20.2 Calculus of kidney with calculus of ureter	0.003	0.997	0.000
R73 Elevated blood glucose level	0.003	0.997	0.000
U80 Agent resistant to penicillin and related antibiotics	0.003	0.997	0.000
M95.0 Acquired deformity of nose	0.003	0.997	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.003	0.997	0.000
E26.8 Other hyperaldosteronism	0.000	0.997	0.002
E26.1 Secondary hyperaldosteronism	0.000	0.997	0.002
H50.8 Other specified strabismus	0.000	0.997	0.003
K66.8 Other specified disorders of peritoneum	0.000	0.997	0.003
Z48.9 Surgical follow-up care, unspecified	0.003	0.997	0.000
S02.11 Fracture of base of skull (open)	0.002	0.997	0.000
H50.3 Intermittent heterotropia	0.000	0.997	0.002
E20.8 Other hypoparathyroidism	0.000	0.997	0.002
E32.8 Other diseases of thymus	0.000	0.997	0.002
E21.4 Other specified disorders of parathyroid gland	0.000	0.997	0.002
H50.4 Other and unspecified heterotropia	0.000	0.997	0.002
U89.8 Agent resistant to other single specified antibiotic	0.000	0.997	0.003
S50.0 Contusion of elbow	0.003	0.997	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.002	0.997	0.000
E21.2 Other hyperparathyroidism	0.000	0.997	0.002
O00.9 Ectopic pregnancy, unspecified	0.002	0.997	0.000
Z60.2 Living alone	0.003	0.997	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.002	0.997	0.000
Z93.1 Gastrostomy status	0.002	0.998	0.000
O06 Unspecified abortion	0.002	0.998	0.000
H50.6 Mechanical strabismus	0.000	0.998	0.002
E26.9 Hyperaldosteronism, unspecified	0.000	0.998	0.002
H50.0 Convergent concomitant strabismus	0.000	0.998	0.002
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
R82.9 Other and unspecified abnormal finding in urine	0.000	0.998	0.002
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.002	0.998	0.000
E23.0 Hypopituitarism	0.000	0.998	0.002
F10.3 Withdrawal state	0.002	0.998	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.002	0.998	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.002	0.998	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O00 Ectopic pregnancy	0.002	0.998	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.000	0.998	0.002
M89.96 Disorder of bone, unspecified (Lower leg)	0.002	0.998	0.000
S51.8 Open wound of other parts of forearm	0.000	0.998	0.002
M60.08 Infective myositis (Other)	0.002	0.998	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.998	0.002
E23.1 Drug-induced hypopituitarism	0.000	0.998	0.002
E26.0 Primary hyperaldosteronism	0.000	0.998	0.002
M89.9 Disorder of bone, unspecified	0.002	0.998	0.000
O07 Failed attempted abortion	0.002	0.998	0.000
E22.8 Other hyperfunction of pituitary gland	0.000	0.998	0.002
O05 Other abortion	0.002	0.998	0.000
O01 Hydatidiform mole	0.002	0.998	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations