TreeWAS – Variant ID: rs7005606

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C73 Malignant neoplasm of thyroid gland	0.213	0.787	0.000
E06.3 Autoimmune thyroiditis	0.091	0.909	0.000
E06 Thyroiditis	0.088	0.912	0.000
E06.9 Thyroiditis, unspecified	0.080	0.920	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.080	0.920	0.000
E00-E07 Disorders of thyroid gland	0.080	0.920	0.000
E05.9 Thyrotoxicosis, unspecified	0.077	0.923	0.000
E04 Other non-toxic goitre	0.077	0.923	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.075	0.925	0.000
E04.9 Non-toxic goitre, unspecified	0.070	0.930	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.070	0.930	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.066	0.934	0.000
E04.2 Non-toxic multinodular goitre	0.065	0.935	0.000
E06.1 Subacute thyroiditis	0.064	0.935	0.000
E06.4 Drug-induced thyroiditis	0.063	0.937	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.063	0.937	0.000
E06.0 Acute thyroiditis	0.063	0.937	0.000
E04.1 Non-toxic single thyroid nodule	0.063	0.937	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.063	0.937	0.000
E06.5 Other chronic thyroiditis	0.062	0.938	0.000
E05.5 Thyroid crisis or storm	0.058	0.942	0.000
E05.4 Thyrotoxicosis factitia	0.058	0.942	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.058	0.942	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.057	0.943	0.000
E00 Congenital iodine-deficiency syndrome	0.057	0.943	0.000
E04.8 Other specified non-toxic goitre	0.055	0.945	0.000
C75 Malignant neoplasm of other endocrine glands and related structures	0.054	0.946	0.000
E07 Other disorders of thyroid	0.052	0.948	0.000
E05.8 Other thyrotoxicosis	0.051	0.948	0.000
E04.0 Non-toxic diffuse goitre	0.050	0.950	0.000
C74 Malignant neoplasm of adrenal gland	0.047	0.952	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.045	0.955	0.000
E07.8 Other specified disorders of thyroid	0.043	0.957	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.041	0.959	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.041	0.959	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.041	0.959	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.041	0.959	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.041	0.959	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.041	0.959	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.041	0.959	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.041	0.959	0.000
C75.1 Pituitary gland	0.040	0.960	0.000
C75.0 Parathyroid gland	0.039	0.961	0.000
C75.8 Pluriglandular involvement, unspecified	0.039	0.961	0.000
C75.5 Aortic body and other paraganglia	0.039	0.961	0.000
C75.4 Carotid body	0.039	0.961	0.000
C75.3 Pineal gland	0.039	0.961	0.000
C75.2 Craniopharyngeal duct	0.039	0.961	0.000
E07.1 Dyshormogenetic goitre	0.038	0.962	0.000
E07.0 Hypersecretion of calcitonin	0.038	0.962	0.000
C75.9 Endocrine gland, unspecified	0.037	0.963	0.000
C74.1 Medulla of adrenal gland	0.036	0.964	0.000
C74.0 Cortex of adrenal gland	0.031	0.969	0.000
C74.9 Adrenal gland, unspecified	0.029	0.971	0.000
E07.9 Disorder of thyroid, unspecified	0.023	0.976	0.000
E03 Other hypothyroidism	0.011	0.988	0.001
J31.0 Chronic rhinitis	0.000	0.989	0.011
E03.1 Congenital hypothyroidism without goitre	0.010	0.990	0.000
E03.5 Myxoedema coma	0.008	0.991	0.001
E03.4 Atrophy of thyroid (acquired)	0.008	0.991	0.001
E03.3 Postinfectious hypothyroidism	0.008	0.991	0.001
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.000	0.992	0.008
R82.9 Other and unspecified abnormal finding in urine	0.000	0.992	0.008
J31.2 Chronic pharyngitis	0.000	0.992	0.008
E03.0 Congenital hypothyroidism with diffuse goitre	0.007	0.992	0.001
K85.9 Acute pancreatitis, unspecified	0.007	0.993	0.000
Z91.6 Personal history of other physical trauma	0.000	0.993	0.007
J31.1 Chronic nasopharyngitis	0.000	0.993	0.006
O75.8 Other specified complications of labour and delivery	0.006	0.994	0.000
R82 Other abnormal findings in urine	0.000	0.994	0.006
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.005	0.994	0.001
D59.1 Other autoimmune haemolytic anaemias	0.006	0.994	0.000
Z60.2 Living alone	0.000	0.994	0.006
Z80.9 Family history of malignant neoplasm, unspecified	0.005	0.995	0.000
N21.0 Calculus in bladder	0.000	0.995	0.005
Z71.1 Person with feared complaint in whom no diagnosis is made	0.005	0.995	0.000
D12.3 Transverse colon	0.000	0.995	0.005
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.005	0.995	0.000
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.000	0.995	0.005
R82.4 Acetonuria	0.000	0.995	0.005
R82.1 Myoglobinuria	0.000	0.995	0.005
R82.7 Abnormal findings on microbiological examination of urine	0.000	0.995	0.004
M86.98 Osteomyelitis, unspecified (Other)	0.000	0.996	0.004
E03.8 Other specified hypothyroidism	0.003	0.996	0.002
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.000	0.996	0.004
R82.3 Haemoglobinuria	0.000	0.996	0.004
R82.2 Biliuria	0.000	0.996	0.004
R82.0 Chyluria	0.000	0.996	0.004
Z60 Problems related to social environment	0.000	0.996	0.004
O46.9 Antepartum haemorrhage, unspecified	0.000	0.996	0.004
R40.2 Coma, unspecified	0.000	0.996	0.004
H44.0 Purulent endophthalmitis	0.000	0.996	0.004
Z63 Other problems related to primary support group, including family circumstances	0.000	0.996	0.004
Z63.0 Problems in relationship with spouse or partner	0.000	0.996	0.004
L97 Ulcer of lower limb, not elsewhere classified	0.004	0.996	0.000
D59 Acquired haemolytic anaemia	0.004	0.996	0.000
Z60.9 Problem related to social environment, unspecified	0.000	0.996	0.004
Z57.2 Occupational exposure to dust	0.000	0.996	0.004
R82.8 Abnormal findings on cytological and histological examination of urine	0.000	0.996	0.004
Z63.7 Other stressful life events affecting family and household	0.000	0.996	0.004
Z63.5 Disruption of family by separation and divorce	0.000	0.996	0.004
M86.9 Osteomyelitis, unspecified	0.000	0.996	0.004
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.996	0.004
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.996	0.004
Z96.8 Presence of other specified functional implants	0.004	0.996	0.000
Y40.0 Penicillins	0.000	0.996	0.004
D59.0 Drug-induced autoimmune haemolytic anaemia	0.003	0.996	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.003	0.996	0.000
Z63.4 Disappearance and death of family member	0.000	0.997	0.003
Z60.5 Target of perceived adverse discrimination and persecution	0.000	0.997	0.003
Z60.4 Social exclusion and rejection	0.000	0.997	0.003
Z60.3 Acculturation difficulty	0.000	0.997	0.003
Z60.1 Atypical parenting situation	0.000	0.997	0.003
Z60.0 Problems of adjustment to life-cycle transitions	0.000	0.997	0.003
Z63.6 Dependent relative needing care at home	0.000	0.997	0.003
H60.1 Cellulitis of external ear	0.000	0.997	0.003
O75 Other complications of labour and delivery, not elsewhere classified	0.003	0.997	0.000
Z57 Occupational exposure to risk-factors	0.000	0.997	0.003
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.000	0.997	0.003
Z63.9 Problem related to primary support group, unspecified	0.000	0.997	0.003
Z63.3 Absence of family member	0.000	0.997	0.003
Z63.2 Inadequate family support	0.000	0.997	0.003
Z63.1 Problems in relationship with parents and in-laws	0.000	0.997	0.003
D59.9 Acquired haemolytic anaemia, unspecified	0.003	0.997	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.003	0.997	0.000
H93.1 Tinnitus	0.000	0.997	0.003
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.000	0.997	0.003
N34.2 Other urethritis	0.000	0.997	0.003
N92.6 Irregular menstruation, unspecified	0.000	0.997	0.003
M86.94 Osteomyelitis, unspecified (Hand)	0.000	0.997	0.003
D59.8 Other acquired haemolytic anaemias	0.003	0.997	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.003	0.997	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.003	0.997	0.000
D59.3 Haemolytic-uraemic syndrome	0.003	0.997	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.003	0.997	0.000
Z63.8 Other specified problems related to primary support group	0.000	0.997	0.003
Z61 Problems related to negative life events in childhood	0.000	0.997	0.003
M86.93 Osteomyelitis, unspecified (Forearm)	0.000	0.997	0.003
M86.92 Osteomyelitis, unspecified (Upper arm)	0.000	0.997	0.003
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.000	0.997	0.003
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.000	0.997	0.003
Z57.3 Occupational exposure to other air contaminants	0.000	0.997	0.003
Z60.8 Other problems related to social environment	0.000	0.997	0.003
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.003
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.997	0.003
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
H66.3 Other chronic suppurative otitis media	0.000	0.997	0.003
H44.4 Hypotony of eye	0.000	0.997	0.003
O34.2 Maternal care due to uterine scar from previous surgery	0.003	0.997	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.000	0.997	0.003
S27.1 Traumatic haemothorax	0.000	0.997	0.003
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.000	0.997	0.003
H18.5 Hereditary corneal dystrophies	0.003	0.997	0.000
O75.9 Complication of labour and delivery, unspecified	0.003	0.997	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.003	0.997	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.003	0.997	0.000
H44.1 Other endophthalmitis	0.000	0.997	0.003
O75.5 Delayed delivery after artificial rupture of membranes	0.003	0.997	0.000
O75.4 Other complications of obstetric surgery and procedures	0.003	0.997	0.000
O75.1 Shock during or following labour and delivery	0.003	0.997	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.000	0.997	0.003
Z57.7 Occupational exposure to vibration	0.000	0.997	0.003
Z57.6 Occupational exposure to extreme temperature	0.000	0.997	0.003
Z57.4 Occupational exposure to toxic agents in agriculture	0.000	0.997	0.003
Z57.1 Occupational exposure to radiation	0.000	0.997	0.003
Z57.0 Occupational exposure to noise	0.000	0.997	0.003
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.000	0.997	0.003
Z62 Other problems related to upbringing	0.000	0.997	0.003
Z55 Problems related to education and literacy	0.000	0.997	0.003
H44 Disorders of globe	0.000	0.997	0.003
O75.3 Other infection during labour	0.002	0.997	0.000
I78.1 Naevus, nonneoplastic	0.003	0.997	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.000	0.997	0.002
Q51.3 Bicornate uterus	0.003	0.997	0.000
R81 Glycosuria	0.000	0.997	0.002
Z58 Problems related to physical environment	0.000	0.997	0.002
G00.9 Bacterial meningitis, unspecified	0.002	0.997	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.997	0.002
Z61.6 Problems related to alleged physical abuse of child	0.000	0.998	0.002
H18.4 Corneal degeneration	0.002	0.998	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.002	0.998	0.000
Z61.9 Negative life events in childhood, unspecified	0.000	0.998	0.002
Z61.8 Other negative life events in childhood	0.000	0.998	0.002
Z61.7 Personal frightening experience in childhood	0.000	0.998	0.002
Z61.3 Events resulting in loss of self-esteem in childhood	0.000	0.998	0.002
Z61.2 Altered pattern of family relationships in childhood	0.000	0.998	0.002
Z61.1 Removal from home in childhood	0.000	0.998	0.002
Z61.0 Loss of love relationship in childhood	0.000	0.998	0.002
Z65 Problems related to other psychosocial circumstances	0.000	0.998	0.002
O46.8 Other antepartum haemorrhage	0.000	0.998	0.002
Z75.1 Person awaiting admission to adequate facility elsewhere	0.000	0.998	0.002
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.002	0.998	0.000
G25.0 Essential tremor	0.002	0.998	0.000
H18 Other disorders of cornea	0.002	0.998	0.000
H18.8 Other specified disorders of cornea	0.002	0.998	0.000
G00 Bacterial meningitis, not elsewhere classified	0.002	0.998	0.000
N21 Calculus of lower urinary tract	0.000	0.998	0.002
G25.8 Other specified extrapyramidal and movement disorders	0.002	0.998	0.000
Z57.8 Occupational exposure to other risk-factors	0.000	0.998	0.002
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
G25.9 Extrapyramidal and movement disorder, unspecified	0.002	0.998	0.000
Z99.8 Dependence on other enabling machines and devices	0.000	0.998	0.002
G25 Other extrapyramidal and movement disorders	0.002	0.998	0.000
Z64 Problems related to certain psychosocial circumstances	0.000	0.998	0.002
Z58.7 Exposure to tobacco smoke	0.000	0.998	0.002
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.000	0.998	0.002
S27 Injury of other and unspecified intrathoracic organs	0.000	0.998	0.002
G59.0 Diabetic mononeuropathy	0.002	0.998	0.000
H18.6 Keratoconus	0.002	0.998	0.000
H18.1 Bullous keratopathy	0.002	0.998	0.000
S27.8 Injury of other specified intrathoracic organs	0.000	0.998	0.002
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.002	0.998	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.000	0.998	0.002
Z55.8 Other problems relating to education and literacy	0.000	0.998	0.002
Z55.4 Educational maladjustment and discord with teachers and classmates	0.000	0.998	0.002
Z55.3 Underachievement in school	0.000	0.998	0.002
Z55.2 Failed examinations	0.000	0.998	0.002
Z55.1 Schooling unavailable and unattainable	0.000	0.998	0.002
Z55.0 Illiteracy and low-level literacy	0.000	0.998	0.002
Z62.9 Problem related to upbringing, unspecified	0.000	0.998	0.002
Z62.8 Other specified problems related to upbringing	0.000	0.998	0.002
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.000	0.998	0.002
Z62.5 Other problems related to neglect in upbringing	0.000	0.998	0.002
Z62.4 Emotional neglect of child	0.000	0.998	0.002
Z62.3 Hostility towards and scapegoating of child	0.000	0.998	0.002
Z62.2 Institutional upbringing	0.000	0.998	0.002
Z62.1 Parental overprotection	0.000	0.998	0.002
Z62.0 Inadequate parental supervision and control	0.000	0.998	0.002
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.000	0.998	0.002
H44.6 Retained (old) intraocular foreign body, magnetic	0.000	0.998	0.002
H44.3 Other degenerative disorders of globe	0.000	0.998	0.002
T38.1 Thyroid hormones and substitutes	0.000	0.998	0.002
Z89.6 Acquired absence of leg above knee	0.000	0.998	0.002
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.998	0.002
Z59 Problems related to housing and economic circumstances	0.000	0.998	0.002
G00.1 Pneumococcal meningitis	0.002	0.998	0.000
H44.8 Other disorders of globe	0.000	0.998	0.002
S27.3 Other injuries of lung	0.000	0.998	0.002
Z58.5 Exposure to other pollution	0.000	0.998	0.002
G00-G09 Inflammatory diseases of the central nervous system	0.002	0.998	0.000
H44.5 Degenerated conditions of globe	0.000	0.998	0.002
R80 Isolated proteinuria	0.000	0.998	0.002
O34.8 Maternal care for other abnormalities of pelvic organs	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
M23.5 Chronic instability of knee	0.000	0.998	0.002
N21.8 Other lower urinary tract calculus	0.000	0.998	0.002
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.002
Z58.9 Problem related to physical environment, unspecified	0.000	0.998	0.002
Z58.6 Inadequate drinking-water supply	0.000	0.998	0.002
Z58.4 Exposure to radiation	0.000	0.998	0.002
Z58.3 Exposure to soil pollution	0.000	0.998	0.002
Z58.2 Exposure to water pollution	0.000	0.998	0.002
Z58.0 Exposure to noise	0.000	0.998	0.002
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.998	0.002
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.998	0.002
G25.3 Myoclonus	0.002	0.998	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.998	0.002
S27.2 Traumatic heamopneumothorax	0.000	0.998	0.002
H60 Otitis externa	0.000	0.998	0.002
D29.1 Prostate	0.000	0.998	0.002
L28.0 Lichen simplex chronicus	0.002	0.998	0.000
O75.0 Maternal distress during labour and delivery	0.002	0.998	0.000
H18.3 Changes in corneal membranes	0.002	0.998	0.000
H65.0 Acute serous otitis media	0.000	0.998	0.002
Z65.9 Problem related to unspecified psychosocial circumstances	0.000	0.998	0.002
Z65.5 Exposure to disaster, war and other hostilities	0.000	0.998	0.002
Z65.4 Victim of crime and terrorism	0.000	0.998	0.002
Z65.2 Problems related to release from prison	0.000	0.998	0.002
Z65.1 Imprisonment and other incarceration	0.000	0.998	0.002
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.000	0.998	0.002
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.002	0.998	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.002	0.998	0.000
H65.2 Chronic serous otitis media	0.000	0.998	0.002
H18.7 Other corneal deformities	0.002	0.998	0.000
H60.5 Acute otitis externa, non-infective	0.000	0.998	0.002
K85 Acute pancreatitis	0.002	0.998	0.000
G00.8 Other bacterial meningitis	0.002	0.998	0.000
G00.3 Staphylococcal meningitis	0.002	0.998	0.000
G00.0 Haemophilus meningitis	0.002	0.998	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.998	0.002
N21.9 Calculus of lower urinary tract, unspecified	0.000	0.998	0.002
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G25.5 Other chorea	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.998	0.002
G25.6 Drug-induced tics and other tics of organic origin	0.002	0.998	0.000
G25.4 Drug-induced chorea	0.002	0.998	0.000
G25.1 Drug-induced tremor	0.002	0.998	0.000
K22.5 Diverticulum of oesophagus, acquired	0.000	0.998	0.002
L29.9 Pruritus, unspecified	0.002	0.998	0.000
Z65.8 Other specified problems related to psychosocial circumstances	0.000	0.998	0.002
G00.2 Streptococcal meningitis	0.002	0.998	0.000
H44.9 Disorder of globe, unspecified	0.000	0.998	0.002
Z64.4 Discord with counsellors	0.000	0.998	0.002
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.000	0.998	0.002
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.000	0.998	0.002
Z64.1 Problems related to multiparity	0.000	0.998	0.002
G25.2 Other specified forms of tremor	0.002	0.998	0.000
S29.9 Unspecified injury of thorax	0.002	0.998	0.000
Z59.0 Homelessness	0.000	0.998	0.002
G09 Sequelae of inflammatory diseases of central nervous system	0.002	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.9 Injury of unspecified intrathoracic organ	0.000	0.998	0.002
S27.7 Multiple injuries of intrathoracic organs	0.000	0.998	0.002
S27.6 Injury of pleura	0.000	0.998	0.002
S27.5 Injury of thoracic trachea	0.000	0.998	0.002
S27.4 Injury of bronchus	0.000	0.998	0.002
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.000	0.998	0.002
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
H60.0 Abscess of external ear	0.000	0.998	0.002
Z58.8 Other problems related to physical environment	0.000	0.998	0.002
Z65.3 Problems related to other legal circumstances	0.000	0.998	0.002
G02.0 Meningitis in viral diseases classified elsewhere	0.002	0.998	0.000
D29.4 Scrotum	0.000	0.998	0.002
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.000	0.998	0.002
G04 Encephalitis, myelitis and encephalomyelitis	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.002	0.998	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.000	0.998	0.002
D05.9 Carcinoma in situ of breast, unspecified	0.002	0.998	0.000
N18.4 Chronic kidney disease, stage 4	0.000	0.998	0.002
Z59.7 Insufficient social insurance and welfare support	0.000	0.998	0.002
Z59.6 Low income	0.000	0.998	0.002
Z59.5 Extreme poverty	0.000	0.998	0.002
Z59.4 Lack of adequate food	0.000	0.998	0.002
Z59.3 Problems related to living in residential institution	0.000	0.998	0.002
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.002	0.998	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.002	0.998	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.000	0.998	0.002
G03 Meningitis due to other and unspecified causes	0.002	0.998	0.000
H65 Nonsuppurative otitis media	0.000	0.998	0.002
M23.57 Chronic instability of knee (Capsular ligament)	0.000	0.998	0.002
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.000	0.998	0.002
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.000	0.998	0.002
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.998	0.002
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.998	0.002
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.998	0.002
H60.8 Other otitis externa	0.000	0.998	0.002
H60.4 Cholesteatoma of external ear	0.000	0.998	0.002
K85.0 Idiopathic acute pancreatitis	0.002	0.998	0.000
Q51.2 Other doubling of uterus	0.002	0.998	0.000
W19.2 School, other institution and public administrative area	0.000	0.998	0.002
Z75.2 Other waiting period for investigation and treatment	0.000	0.998	0.002
N21.1 Calculus in urethra	0.000	0.998	0.002
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.002	0.998	0.000
H93 Other disorders of ear, not elsewhere classified	0.000	0.998	0.002
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
H60.2 Malignant otitis externa	0.000	0.998	0.002
S27.0 Traumatic pneumothorax	0.000	0.998	0.002
H93.9 Disorder of ear, unspecified	0.000	0.998	0.002
Q51.8 Other congenital malformations of uterus and cervix	0.002	0.998	0.000
Z58.1 Exposure to air pollution	0.000	0.998	0.002
M23.50 Chronic instability of knee (Multiple sites)	0.000	0.998	0.002
K57.1 Diverticular disease of small intestine without perforation or abscess	0.002	0.998	0.000
K85.2 Alcohol-induced acute pancreatitis	0.002	0.998	0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
G02.1 Meningitis in mycoses	0.001	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.001	0.998	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.998	0.002
H18.2 Other corneal oedema	0.002	0.998	0.000
H60.3 Other infective otitis externa	0.000	0.998	0.002
D29 Benign neoplasm of male genital organs	0.000	0.998	0.002
Z56 Problems related to employment and unemployment	0.000	0.998	0.001
D29.0 Penis	0.000	0.998	0.002
K85.3 Drug-induced acute pancreatitis	0.002	0.998	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.000	0.998	0.001
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.000	0.998	0.001
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.000	0.998	0.001
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.000	0.998	0.001
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.000	0.998	0.001
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.000	0.998	0.001
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.000	0.998	0.001
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.000	0.998	0.001
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.000	0.998	0.001
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.000	0.998	0.001
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.002	0.998	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.998	0.002
I42.0 Dilated cardiomyopathy	0.002	0.998	0.000
Z59.1 Inadequate housing	0.000	0.998	0.001
H66 Suppurative and unspecified otitis media	0.000	0.998	0.002
G01 Meningitis in bacterial diseases classified elsewhere	0.001	0.998	0.000
G04.1 Tropical spastic paraplegia	0.001	0.998	0.000
G04.0 Acute disseminated encephalitis	0.001	0.998	0.000
H93.8 Other specified disorders of ear	0.000	0.998	0.002
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.001	0.998	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.001	0.998	0.000
Q51.6 Embryonic cyst of cervix	0.001	0.998	0.000
Q51.5 Agenesis and aplasia of cervix	0.001	0.998	0.000
Q51.0 Agenesis and aplasia of uterus	0.001	0.998	0.000
D29.3 Epididymis	0.000	0.998	0.001
G03.8 Meningitis due to other specified causes	0.001	0.998	0.000
G03.2 Benign recurrent meningitis [Mollaret]	0.001	0.998	0.000
G03.1 Chronic meningitis	0.001	0.998	0.000
G03.0 Nonpyogenic meningitis	0.001	0.998	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.998	0.002
X67.9 Unspecified place	0.000	0.998	0.002
M94.26 Chondromalacia (Lower leg)	0.000	0.998	0.002
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.001	0.998	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.002	0.998	0.000
G03.9 Meningitis, unspecified	0.001	0.998	0.000
H93.0 Degenerative and vascular disorders of ear	0.000	0.998	0.001
Z64.0 Problems related to unwanted pregnancy	0.000	0.998	0.001
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
Z75 Problems related to medical facilities and other health care	0.000	0.998	0.002
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.998	0.002
L43.8 Other lichen planus	0.000	0.998	0.001
O34.1 Maternal care for tumour of corpus uteri	0.001	0.998	0.000
D29.2 Testis	0.000	0.998	0.001
Z75.4 Unavailability and inaccessibility of other helping agencies	0.000	0.998	0.001
F33.9 Recurrent depressive disorder, unspecified	0.000	0.998	0.002
H65.1 Other acute nonsuppurative otitis media	0.000	0.998	0.001
L28.1 Prurigo nodularis	0.001	0.998	0.000
Z56.7 Other and unspecified problems related to employment	0.000	0.998	0.001
Z75.3 Unavailability and inaccessibility of health-care facilities	0.000	0.998	0.001
M43.16 Spondylolisthesis (Lumbar region)	0.001	0.999	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.999	0.001
C17.9 Small intestine, unspecified	0.000	0.999	0.001
D29.9 Male genital organ, unspecified	0.000	0.999	0.001
D29.7 Other male genital organs	0.000	0.999	0.001
Z56.5 Uncongenial work	0.000	0.999	0.001
Z56.2 Threat of job loss	0.000	0.999	0.001
Z56.1 Change of job	0.000	0.999	0.001
D55-D59 Haemolytic anaemias	0.001	0.999	0.000
H66.0 Acute suppurative otitis media	0.000	0.999	0.001
Q53.1 Undescended testicle, unilateral	0.001	0.999	0.000
Z43.5 Attention to cyctostomy	0.001	0.999	0.000
K85.1 Biliary acute pancreatitis	0.001	0.999	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.001	0.999	0.001
O34 Maternal care for known or suspected abnormality of pelvic organs	0.001	0.999	0.000
Q51.4 Unicornate uterus	0.001	0.999	0.000
Z56.3 Stressful work schedule	0.000	0.999	0.001
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.999	0.001
H93.3 Disorders of acoustic nerve	0.000	0.999	0.001
H93.2 Other abnormal auditory perceptions	0.000	0.999	0.001
I51.3 Intracardiac thrombosis, not elsewhere classified	0.001	0.999	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.001	0.999	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.999	0.001
T38.9 Other and unspecified hormone antagonists	0.000	0.999	0.001
T38.7 Androgens and anabolic congeners	0.000	0.999	0.001
T38.5 Other oestrogens and progestogens	0.000	0.999	0.001
T38.4 Oral contraceptives	0.000	0.999	0.001
T38.2 Antithyroid drugs	0.000	0.999	0.001
T38.0 Glucocorticoids and synthetic analogues	0.000	0.999	0.001
Z56.4 Discord with boss and workmates	0.000	0.999	0.001
Z75.9 Unspecified problem related to medical facilities and other health care	0.000	0.999	0.001
Z75.0 Medical services not available in home	0.000	0.999	0.001
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.000	0.999	0.001
M86.87 Other osteomyelitis (Ankle and foot)	0.000	0.999	0.001
H66.4 Suppurative otitis media, unspecified	0.000	0.999	0.001
J81 Pulmonary oedema	0.000	0.999	0.001
M86 Osteomyelitis	0.000	0.999	0.001
M43.17 Spondylolisthesis (Lumbosacral region)	0.001	0.999	0.000
J86.0 Pyothorax with fistula	0.000	0.999	0.001
D56 Thalassaemia	0.001	0.999	0.000
I37.1 Pulmonary valve insufficiency	0.001	0.999	0.000
O71.7 Obstetric haematoma of pelvis	0.000	0.999	0.001
D55 Anaemia due to enzyme disorders	0.001	0.999	0.000
M23.49 Loose body in knee-Unspec lig/men	0.000	0.999	0.001
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.001	0.999	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.999	0.001
K85.8 Other acute pancreatitis	0.001	0.999	0.000
O71.4 Obstetric high vaginal laceration alone	0.000	0.999	0.001
C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.999	0.001
L28 Lichen simplex chronicus and prurigo	0.001	0.999	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.001	0.999	0.000
L43.9 Lichen planus, unspecified	0.000	0.999	0.001
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.001	0.999	0.000
O34.6 Maternal care for abnormality of vagina	0.001	0.999	0.000
Q55.0 Absence and aplasia of testis	0.001	0.999	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.999	0.001
D57 Sickle-cell disorders	0.001	0.999	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.999	0.001
H70.1 Chronic mastoiditis	0.000	0.999	0.001
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.999	0.001
M86.8 Other osteomyelitis	0.000	0.999	0.001
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.999	0.001
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.001	0.999	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.001	0.999	0.000
R52.1 Chronic intractable pain	0.000	0.999	0.001
H70 Mastoiditis and related conditions	0.000	0.999	0.001
Q53 Undescended testicle	0.001	0.999	0.000
D56.3 Thalassaemia trait	0.001	0.999	0.000
D56.1 Beta thalassaemia	0.001	0.999	0.000
D75.2 Essential thrombocytosis	0.000	0.999	0.001
H70.8 Other mastoiditis and related conditions	0.000	0.999	0.001
M86.6 Other chronic osteomyelitis	0.000	0.999	0.001
O34.5 Maternal care for other abnormalities of gravid uterus	0.001	0.999	0.000
M43.12 Spondylolisthesis (Cervical region)	0.001	0.999	0.000
D56.9 Thalassaemia, unspecified	0.001	0.999	0.000
D56.8 Other thalassaemias	0.001	0.999	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.001	0.999	0.000
D56.2 Delta-beta thalassaemia	0.001	0.999	0.000
D56.0 Alpha thalassaemia	0.001	0.999	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.000	0.999	0.001
M86.5 Other chronic haematogenous osteomyelitis	0.000	0.999	0.001
M86.3 Chronic multifocal osteomyelitis	0.000	0.999	0.001
M86.2 Subacute osteomyelitis	0.000	0.999	0.001
M86.0 Acute haematogenous osteomyelitis	0.000	0.999	0.001
D55.9 Anaemia due to enzyme disorder, unspecified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations