TreeWAS – Variant ID: rs701230

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K76 Other diseases of liver	0.065	0.935	0.000
K74.6 Other and unspecified cirrhosis of liver	0.065	0.935	0.000
K74 Fibrosis and cirrhosis of liver	0.065	0.935	0.000
K70-K77 Diseases of liver	0.064	0.936	0.000
K76.6 Portal hypertension	0.063	0.937	0.000
K76.9 Liver disease, unspecified	0.060	0.940	0.000
K74.0 Hepatic fibrosis	0.057	0.943	0.000
K76.8 Other specified diseases of liver	0.054	0.946	0.000
K76.7 Hepatorenal syndrome	0.054	0.946	0.000
K72 Hepatic failure, not elsewhere classified	0.053	0.947	0.000
K70 Alcoholic liver disease	0.052	0.948	0.000
K73 Chronic hepatitis, not elsewhere classified	0.051	0.949	0.000
K72.9 Hepatic failure, unspecified	0.048	0.952	0.000
K74.5 Biliary cirrhosis, unspecified	0.048	0.952	0.000
K76.5 Hepatic veno-occlusive disease	0.047	0.953	0.000
K76.4 Peliosis hepatis	0.047	0.953	0.000
K76.3 Infarction of liver	0.047	0.953	0.000
K76.2 Central haemorrhagic necrosis of liver	0.047	0.953	0.000
K76.1 Chronic passive congestion of liver	0.047	0.953	0.000
K74.4 Secondary biliary cirrhosis	0.047	0.953	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.047	0.953	0.000
K74.1 Hepatic sclerosis	0.047	0.953	0.000
K77 Liver disorders in diseases classified elsewhere	0.046	0.954	0.000
K71 Toxic liver disease	0.046	0.954	0.000
K75 Other inflammatory liver diseases	0.046	0.954	0.000
K70.9 Alcoholic liver disease, unspecified	0.043	0.957	0.000
K70.3 Alcoholic cirrhosis of liver	0.042	0.958	0.000
K70.4 Alcoholic hepatic failure	0.041	0.959	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.040	0.959	0.000
K72.1 Chronic hepatic failure	0.038	0.961	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.037	0.963	0.000
K73.9 Chronic hepatitis, unspecified	0.037	0.963	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.036	0.963	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.036	0.963	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.036	0.963	0.000
K74.3 Primary biliary cirrhosis	0.036	0.964	0.000
K75.8 Other specified inflammatory liver diseases	0.035	0.965	0.000
K75.4 Autoimmune hepatitis	0.035	0.965	0.000
K71.9 Toxic liver disease, unspecified	0.033	0.967	0.000
K71.8 Toxic liver disease with other disorders of liver	0.033	0.967	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.033	0.967	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.033	0.967	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.033	0.967	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.033	0.967	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.033	0.967	0.000
K71.2 Toxic liver disease with acute hepatitis	0.033	0.967	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.033	0.967	0.000
K71.0 Toxic liver disease with cholestasis	0.033	0.967	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.033	0.967	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.033	0.967	0.000
K70.0 Alcoholic fatty liver	0.033	0.967	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.033	0.967	0.000
K75.2 Nonspecific reactive hepatitis	0.033	0.967	0.000
K75.1 Phlebitis of portal vein	0.033	0.967	0.000
K72.0 Acute and subacute hepatic failure	0.032	0.968	0.000
K75.9 Inflammatory liver disease, unspecified	0.031	0.969	0.000
K70.1 Alcoholic hepatitis	0.030	0.970	0.000
K75.0 Abscess of liver	0.030	0.970	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.020	0.980	0.000
E87.5 Hyperkalaemia	0.020	0.980	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.019	0.981	0.000
E87.7 Fluid overload	0.019	0.981	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.018	0.982	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.018	0.982	0.000
E87.6 Hypokalaemia	0.018	0.982	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.018	0.982	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.018	0.982	0.000
C83.3 Large cell (diffuse)	0.017	0.983	0.000
E87.2 Acidosis	0.017	0.983	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.017	0.983	0.000
C88 Malignant immunoproliferative diseases	0.016	0.984	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.015	0.985	0.000
C92 Myeloid leukaemia	0.015	0.985	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.015	0.985	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.015	0.985	0.000
E87.3 Alkalosis	0.015	0.985	0.000
E87.4 Mixed disorder of acid-base balance	0.014	0.986	0.000
C81 Hodgkin's disease	0.014	0.986	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.014	0.986	0.000
C83.1 Small cleaved cell (diffuse)	0.014	0.986	0.000
C85.1 B-cell lymphoma, unspecified	0.014	0.986	0.000
C92.1 Chronic myeloid leukaemia	0.014	0.986	0.000
I84.2 Internal haemorrhoids without complication	0.014	0.986	0.000
C83.0 Small cell (diffuse)	0.013	0.987	0.000
C91 Lymphoid leukaemia	0.013	0.987	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.013	0.987	0.000
C83.7 Burkitt's tumour	0.013	0.987	0.000
C83.6 Undifferentiated (diffuse)	0.013	0.987	0.000
C83.5 Lymphoblastic (diffuse)	0.013	0.987	0.000
C83.4 Immunoblastic (diffuse)	0.013	0.987	0.000
C83.2 Mixed small and large cell (diffuse)	0.013	0.987	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.013	0.987	0.000
C95 Leukaemia of unspecified cell type	0.013	0.987	0.000
C94 Other leukaemias of specified cell type	0.013	0.987	0.000
C93 Monocytic leukaemia	0.013	0.987	0.000
C86 Other specified types of T/NK-cell lymphoma	0.013	0.987	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.013	0.987	0.000
C85.0 Lymphosarcoma	0.013	0.987	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.013	0.987	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.012	0.988	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.011	0.988	0.000
C88.7 Other malignant immunoproliferative diseases	0.011	0.988	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.011	0.988	0.000
C88.3 Immunoproliferative small intestinal disease	0.011	0.988	0.000
C88.2 Gamma heavy chain disease	0.011	0.988	0.000
C88.1 Alpha heavy chain disease	0.011	0.988	0.000
C81.9 Hodgkin's disease, unspecified	0.011	0.988	0.000
E87.0 Hyperosmolality and hypernatraemia	0.011	0.989	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.011	0.989	0.000
C92.9 Myeloid leukaemia, unspecified	0.011	0.989	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.011	0.989	0.000
C92.7 Other myeloid leukaemia	0.011	0.989	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.011	0.989	0.000
C92.5 Acute myelomonocytic leukaemia	0.011	0.989	0.000
C92.4 Acute promyelocytic leukaemia	0.011	0.989	0.000
C92.3 Myeloid sarcoma	0.011	0.989	0.000
C92.2 Subacute myeloid leukaemia	0.011	0.989	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.011	0.989	0.000
C91.4 Hairy-cell leukaemia	0.010	0.990	0.000
C81.7 Other Hodgkin's disease	0.010	0.990	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.010	0.990	0.000
C81.3 Lymphocytic depletion	0.010	0.990	0.000
C81.2 Mixed cellularity	0.010	0.990	0.000
C81.1 Nodular sclerosis	0.010	0.990	0.000
C81.0 Lymphocytic predominance	0.010	0.990	0.000
C82.6 Cutaneous follicle centre lymphoma	0.010	0.990	0.000
C82.5 Diffuse follicle centre lymphoma	0.010	0.990	0.000
C82.4 Follicular lymphoma grade IIIb	0.010	0.990	0.000
C82.3 Follicular lymphoma grade IIIa	0.010	0.990	0.000
C82.2 Large cell, follicular	0.010	0.990	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.010	0.990	0.000
C82.0 Small cleaved cell, follicular	0.010	0.990	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.010	0.990	0.000
C92.0 Acute myeloid leukaemia	0.010	0.990	0.000
C91.0 Acute lymphoblastic leukaemia	0.010	0.990	0.000
C91.9 Lymphoid leukaemia, unspecified	0.010	0.990	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.010	0.990	0.000
C91.7 Other lymphoid leukaemia	0.010	0.990	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.010	0.990	0.000
C91.5 Adult T-cell leukaemia	0.010	0.990	0.000
C91.3 Prolymphocytic leukaemia	0.010	0.990	0.000
C91.2 Subacute lymphocytic leukaemia	0.010	0.990	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.009	0.990	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.009	0.990	0.000
C86.4 Blastic NK-cell lymphoma	0.009	0.990	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.009	0.990	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.009	0.990	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.009	0.990	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.009	0.990	0.000
C93.9 Monocytic leukaemia, unspecified	0.009	0.990	0.000
C93.7 Other monocytic leukaemia	0.009	0.990	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.009	0.990	0.000
C93.2 Subacute monocytic leukaemia	0.009	0.990	0.000
C93.1 Chronic monocytic leukaemia	0.009	0.990	0.000
C93.0 Acute monocytic leukaemia	0.009	0.990	0.000
C94.7 Other specified leukaemias	0.009	0.990	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.009	0.990	0.000
C94.5 Acute myelofibrosis	0.009	0.990	0.000
C94.4 Acute panmyelosis	0.009	0.990	0.000
C94.3 Mast cell leukaemia	0.009	0.990	0.000
C94.2 Acute megakaryoblastic leukaemia	0.009	0.990	0.000
C94.1 Chronic erythraemia	0.009	0.990	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.009	0.990	0.000
C95.9 Leukaemia, unspecified	0.009	0.990	0.000
C95.7 Other leukaemia of unspecified cell type	0.009	0.990	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.009	0.990	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.009	0.990	0.000
C95.0 Acute leukaemia of unspecified cell type	0.009	0.990	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.009	0.990	0.000
C96.8 Histiocytic sarcoma	0.009	0.990	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.009	0.990	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.009	0.990	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.009	0.990	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.009	0.990	0.000
C96.3 True histiocytic lymphoma	0.009	0.990	0.000
C96.2 Malignant mast cell tumour	0.009	0.990	0.000
C96.1 Malignant histiocytosis	0.009	0.990	0.000
C96.0 Letterer-Siwe disease	0.009	0.990	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.009	0.990	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.009	0.990	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.009	0.990	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.009	0.990	0.000
C84.4 Peripheral T-cell lymphoma	0.009	0.990	0.000
C84.3 Lymphoepithelioid lymphoma	0.009	0.990	0.000
C84.2 T-zone lymphoma	0.009	0.990	0.000
C84.1 Sezary's diease	0.009	0.990	0.000
C84.0 Mycosis fungoides	0.009	0.990	0.000
C84.5 Other and unspecified T-cell lymphomas	0.009	0.991	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.009	0.991	0.000
C91.1 Chronic lymphocytic leukaemia	0.009	0.991	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.009	0.991	0.000
J44 Other chronic obstructive pulmonary disease	0.009	0.991	0.000
C90.2 Plasmacytoma, extramedullary	0.008	0.992	0.000
C90.3 Solitary plasmacytoma	0.008	0.992	0.000
C90.1 Plasma cell leukaemia	0.008	0.992	0.000
E70-E90 Metabolic disorders	0.008	0.992	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.008	0.992	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.007	0.993	0.000
E86 Volume depletion	0.007	0.993	0.000
E79 Disorders of purine and pyrimidine metabolism	0.007	0.993	0.000
E88 Other metabolic disorders	0.007	0.993	0.000
J46 Status asthmaticus	0.006	0.993	0.000
J40 Bronchitis, not specified as acute or chronic	0.006	0.994	0.000
J40-J47 Chronic lower respiratory diseases	0.006	0.994	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.006	0.994	0.000
E84 Cystic fibrosis	0.006	0.994	0.000
E77 Disorders of glycoprotein metabolism	0.006	0.994	0.000
E76 Disorders of glycosaminoglycan metabolism	0.006	0.994	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.006	0.994	0.000
E74 Other disorders of carbohydrate metabolism	0.006	0.994	0.000
E73 Lactose intolerance	0.006	0.994	0.000
E72 Other disorders of amino-acid metabolism	0.006	0.994	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.006	0.994	0.000
E70 Disorders of aromatic amino-acid metabolism	0.006	0.994	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.006	0.994	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.006	0.994	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.006	0.994	0.000
E85 Amyloidosis	0.005	0.994	0.000
E89.3 Postprocedural hypopituitarism	0.006	0.994	0.000
C90.0 Multiple myeloma	0.005	0.995	0.000
J42 Unspecified chronic bronchitis	0.005	0.995	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.005	0.995	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.005	0.995	0.000
E79.1 Lesch-Nyhan syndrome	0.005	0.995	0.000
E88.9 Metabolic disorder, unspecified	0.005	0.995	0.000
E88.8 Other specified metabolic disorders	0.005	0.995	0.000
E88.3 Tumour lysis syndrome	0.005	0.995	0.000
E88.2 Lipomatosis, not elsewhere classified	0.005	0.995	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.005	0.995	0.000
E05.9 Thyrotoxicosis, unspecified	0.005	0.995	0.000
Z01.8 Other specified special examinations	0.005	0.995	0.000
J41 Simple and mucopurulent chronic bronchitis	0.005	0.995	0.000
E23 Hypofunction and other disorders of pituitary gland	0.004	0.995	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.004	0.996	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.004	0.996	0.000
E70.3 Albinism	0.004	0.996	0.000
E70.2 Disorders of tyrosine metabolism	0.004	0.996	0.000
E70.1 Other hyperphenylalaninaemias	0.004	0.996	0.000
E70.0 Classical phenylketonuria	0.004	0.996	0.000
E71.3 Disorders of fatty-acid metabolism	0.004	0.996	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.004	0.996	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.004	0.996	0.000
E71.0 Maple-syrup-urine disease	0.004	0.996	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.004	0.996	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.004	0.996	0.000
E72.5 Disorders of glycine metabolism	0.004	0.996	0.000
E72.4 Disorders of ornithine metabolism	0.004	0.996	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.004	0.996	0.000
E72.2 Disorders of urea cycle metabolism	0.004	0.996	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.004	0.996	0.000
E72.0 Disorders of amino-acid transport	0.004	0.996	0.000
E73.9 Lactose intolerance, unspecified	0.004	0.996	0.000
E73.8 Other lactose intolerance	0.004	0.996	0.000
E73.1 Secondary lactase deficiency	0.004	0.996	0.000
E73.0 Congenital lactase deficiency	0.004	0.996	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.004	0.996	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.004	0.996	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.004	0.996	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.004	0.996	0.000
E74.2 Disorders of galactose metabolism	0.004	0.996	0.000
E74.1 Disorders of fructose metabolism	0.004	0.996	0.000
E74.0 Glycogen storage disease	0.004	0.996	0.000
E75.6 Lipid storage disorder, unspecified	0.004	0.996	0.000
E75.5 Other lipid storage disorders	0.004	0.996	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.004	0.996	0.000
E75.3 Sphingolipidosis, unspecified	0.004	0.996	0.000
E75.2 Other sphingolipidosis	0.004	0.996	0.000
E75.1 Other gangliosidosis	0.004	0.996	0.000
E75.0 GM2 gangliosidosis	0.004	0.996	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.004	0.996	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.004	0.996	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.004	0.996	0.000
E76.2 Other mucopolysaccharidoses	0.004	0.996	0.000
E76.1 Mucopolysaccharidosis, type II	0.004	0.996	0.000
E76.0 Mucopolysaccharidosis, type I	0.004	0.996	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.004	0.996	0.000
E77.8 Other disorders of glycoprotein metabolism	0.004	0.996	0.000
E77.1 Defects in glycoprotein degradation	0.004	0.996	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.004	0.996	0.000
E84.9 Cystic fibrosis, unspecified	0.004	0.996	0.000
E84.8 Cystic fibrosis with other manifestations	0.004	0.996	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.004	0.996	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.004	0.996	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.004	0.996	0.000
E20-E35 Disorders of other endocrine glands	0.004	0.996	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.004	0.996	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.004	0.996	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.004	0.996	0.000
E89.5 Postprocedural testicular hypofunction	0.004	0.996	0.000
E89.4 Postprocedural ovarian failure	0.004	0.996	0.000
E89.1 Postprocedural hypoinsulinaemia	0.004	0.996	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.004	0.996	0.000
E85.8 Other amyloidosis	0.004	0.996	0.000
E85.4 Organ-limited amyloidosis	0.004	0.996	0.000
E85.3 Secondary systemic amyloidosis	0.004	0.996	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.004	0.996	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.004	0.996	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.004	0.996	0.000
E23.0 Hypopituitarism	0.004	0.996	0.000
E24 Cushing's syndrome	0.004	0.996	0.000
E24.9 Cushing's syndrome, unspecified	0.004	0.996	0.000
E34 Other endocrine disorders	0.004	0.996	0.000
J43 Emphysema	0.004	0.996	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.996	0.004
E05 Thyrotoxicosis [hyperthyroidism]	0.004	0.996	0.000
E85.9 Amyloidosis, unspecified	0.004	0.996	0.000
J33.8 Other polyp of sinus	0.004	0.996	0.000
E23.2 Diabetes insipidus	0.004	0.996	0.000
E89.2 Postprocedural hypoparathyroidism	0.004	0.996	0.000
E34.8 Other specified endocrine disorders	0.004	0.996	0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.003	0.996	0.000
J41.1 Mucopurulent chronic bronchitis	0.003	0.996	0.000
J41.0 Simple chronic bronchitis	0.003	0.996	0.000
E29 Testicular dysfunction	0.004	0.996	0.000
E22 Hyperfunction of pituitary gland	0.004	0.996	0.000
D25.2 Subserosal leiomyoma of uterus	0.000	0.996	0.004
E34.9 Endocrine disorder, unspecified	0.003	0.996	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.004	0.996	0.000
E23.7 Disorder of pituitary gland, unspecified	0.003	0.996	0.000
E23.6 Other disorders of pituitary gland	0.003	0.996	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.003	0.996	0.000
E23.1 Drug-induced hypopituitarism	0.003	0.996	0.000
E28 Ovarian dysfunction	0.003	0.996	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.003	0.997	0.000
E80.6 Other disorders of bilirubin metabolism	0.003	0.997	0.000
E80.5 Crigler-Najjar syndrome	0.003	0.997	0.000
E80.3 Defects of catalase and peroxydase	0.003	0.997	0.000
E80.2 Other porphyria	0.003	0.997	0.000
E80.1 Porphyria cutanea tarda	0.003	0.997	0.000
E80.0 Hereditary erythropoietic porphyria	0.003	0.997	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.997	0.003
E35 Disorders of endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E32 Diseases of thymus	0.003	0.997	0.000
E31 Polyglandular dysfunction	0.003	0.997	0.000
E30 Disorders of puberty, not elsewhere classified	0.003	0.997	0.000
E25 Adrenogenital disorders	0.003	0.997	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.003	0.997	0.000
E26 Hyperaldosteronism	0.003	0.997	0.000
E20 Hypoparathyroidism	0.003	0.997	0.000
M10.99 Gout, unspecified (Site unspecified)	0.003	0.997	0.000
E24.8 Other Cushing's syndrome	0.003	0.997	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.003	0.997	0.000
E24.3 Ectopic ACTH syndrome	0.003	0.997	0.000
E24.2 Drug-induced Cushing's syndrome	0.003	0.997	0.000
E24.1 Nelson's syndrome	0.003	0.997	0.000
E24.0 Pituitary-dependent Cushing's disease	0.003	0.997	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.003	0.997	0.000
E00-E07 Disorders of thyroid gland	0.003	0.997	0.000
E34.5 Androgen resistance syndrome	0.003	0.997	0.000
E34.4 Constitutional tall stature	0.003	0.997	0.000
E34.3 Short stature, not elsewhere classified	0.003	0.997	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.003	0.997	0.000
E34.1 Other hypersecretion of intestinal hormones	0.003	0.997	0.000
E34.0 Carcinoid syndrome	0.003	0.997	0.000
J43.8 Other emphysema	0.003	0.997	0.000
J43.1 Panlobular emphysema	0.003	0.997	0.000
J43.0 MacLeod's syndrome	0.003	0.997	0.000
E05.8 Other thyrotoxicosis	0.003	0.997	0.000
E05.5 Thyroid crisis or storm	0.003	0.997	0.000
E05.4 Thyrotoxicosis factitia	0.003	0.997	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.003	0.997	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.003	0.997	0.000
J43.2 Centrilobular emphysema	0.003	0.997	0.000
E83 Disorders of mineral metabolism	0.003	0.997	0.000
E29.1 Testicular hypofunction	0.003	0.997	0.000
E27 Other disorders of adrenal gland	0.003	0.997	0.000
E22.0 Acromegaly and pituitary gigantism	0.003	0.997	0.000
E89.0 Postprocedural hypothyroidism	0.003	0.997	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.003	0.997	0.000
K08 Other disorders of teeth and supporting structures	0.000	0.997	0.003
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.003	0.997	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.003	0.997	0.000
E22.8 Other hyperfunction of pituitary gland	0.003	0.997	0.000
E22.1 Hyperprolactinaemia	0.003	0.997	0.000
E29.9 Testicular dysfunction, unspecified	0.003	0.997	0.000
E29.8 Other testicular dysfunction	0.003	0.997	0.000
E29.0 Testicular hyperfunction	0.003	0.997	0.000
C50.4 Upper-outer quadrant of breast	0.000	0.997	0.003
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.003	0.997	0.000
E83.5 Disorders of calcium metabolism	0.003	0.997	0.000
E28.9 Ovarian dysfunction, unspecified	0.003	0.997	0.000
E28.8 Other ovarian dysfunction	0.003	0.997	0.000
E28.3 Primary ovarian failure	0.003	0.997	0.000
E28.2 Polycystic ovarian syndrome	0.003	0.997	0.000
E28.1 Androgen excess	0.003	0.997	0.000
E28.0 Oestrogen excess	0.003	0.997	0.000
E25.9 Adrenogenital disorder, unspecified	0.003	0.997	0.000
E25.8 Other adrenogenital disorders	0.003	0.997	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.003	0.997	0.000
E27.2 Addisonian crisis	0.003	0.997	0.000
E30.9 Disorder of puberty, unspecified	0.003	0.997	0.000
E30.8 Other disorders of puberty	0.003	0.997	0.000
E30.1 Precocious puberty	0.003	0.997	0.000
E30.0 Delayed puberty	0.003	0.997	0.000
E31.9 Polyglandular dysfunction, unspecified	0.003	0.997	0.000
E31.8 Other polyglandular dysfunction	0.003	0.997	0.000
E31.1 Polyglandular hyperfunction	0.003	0.997	0.000
E31.0 Autoimmune polyglandular failure	0.003	0.997	0.000
E32.9 Disease of thymus, unspecified	0.003	0.997	0.000
E32.8 Other diseases of thymus	0.003	0.997	0.000
E32.1 Abscess of thymus	0.003	0.997	0.000
E32.0 Persistent hyperplasia of thymus	0.003	0.997	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.003	0.997	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.003	0.997	0.000
K08.3 Retained dental root	0.000	0.997	0.003
E26.9 Hyperaldosteronism, unspecified	0.002	0.997	0.000
E26.8 Other hyperaldosteronism	0.002	0.997	0.000
E26.1 Secondary hyperaldosteronism	0.002	0.997	0.000
E20.8 Other hypoparathyroidism	0.002	0.997	0.000
E20.1 Pseudohypoparathyroidism	0.002	0.997	0.000
E20.0 Idiopathic hypoparathyroidism	0.002	0.997	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.997	0.003
J45 Asthma	0.003	0.997	0.000
E04 Other non-toxic goitre	0.003	0.997	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.003	0.997	0.000
E00 Congenital iodine-deficiency syndrome	0.003	0.997	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.003	0.997	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.000	0.997	0.003
E20.9 Hypoparathyroidism, unspecified	0.002	0.997	0.000
E26.0 Primary hyperaldosteronism	0.002	0.997	0.000
E06 Thyroiditis	0.003	0.997	0.000
J43.9 Emphysema, unspecified	0.003	0.997	0.000
E27.1 Primary adrenocortical insufficiency	0.002	0.997	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.002	0.997	0.000
E83.8 Other disorders of mineral metabolism	0.002	0.997	0.000
E83.2 Disorders of zinc metabolism	0.002	0.997	0.000
E83.0 Disorders of copper metabolism	0.002	0.997	0.000
E40-E46 Malnutrition	0.002	0.997	0.000
E27.5 Adrenomedullary hyperfunction	0.002	0.997	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.002	0.997	0.000
E27.0 Other adrenocortical overactivity	0.002	0.997	0.000
M21.0 Valgus deformity, not elsewhere classified	0.002	0.997	0.000
R63.0 Anorexia	0.002	0.997	0.000
S61.1 Open wound of finger(s) with damage to nail	0.000	0.997	0.002
E50-E64 Other nutritional deficiencies	0.002	0.998	0.000
J47 Bronchiectasis	0.002	0.998	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.000	0.998	0.002
K08.0 Exfoliation of teeth due to systemic causes	0.000	0.998	0.002
E04.2 Non-toxic multinodular goitre	0.002	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.002	0.998	0.000
C45.0 Mesothelioma of pleura	0.002	0.998	0.000
E16 Other disorders of pancreatic internal secretion	0.002	0.998	0.000
Z51.4 Preparatory care for treatment, not elsewhere classified	0.000	0.998	0.002
E15 Nondiabetic hypoglycaemic coma	0.002	0.998	0.000
E06.9 Thyroiditis, unspecified	0.002	0.998	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.998	0.002
E61 Deficiency of other nutrient elements	0.002	0.998	0.000
E27.8 Other specified disorders of adrenal gland	0.002	0.998	0.000
E07 Other disorders of thyroid	0.002	0.998	0.000
E27.9 Disorder of adrenal gland, unspecified	0.002	0.998	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.002	0.998	0.000
E04.0 Non-toxic diffuse goitre	0.002	0.998	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.002	0.998	0.000
E78.2 Mixed hyperlipidaemia	0.002	0.998	0.000
E61.1 Iron deficiency	0.002	0.998	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.002	0.998	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.002	0.998	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.002	0.998	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.002	0.998	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.998	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.002	0.998	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.002	0.998	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.002	0.998	0.000
E04.8 Other specified non-toxic goitre	0.002	0.998	0.000
J45.8 Mixed asthma	0.002	0.998	0.000
J45.1 Nonallergic asthma	0.002	0.998	0.000
E06.5 Other chronic thyroiditis	0.002	0.998	0.000
E06.4 Drug-induced thyroiditis	0.002	0.998	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.002	0.998	0.000
E06.1 Subacute thyroiditis	0.002	0.998	0.000
E06.0 Acute thyroiditis	0.002	0.998	0.000
E80.4 Gilbert's syndrome	0.002	0.998	0.001
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.002	0.998	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.002	0.998	0.000
E45 Retarded development following protein-energy malnutrition	0.002	0.998	0.000
E43 Unspecified severe protein-energy malnutrition	0.002	0.998	0.000
E42 Marasmic kwashiorkor	0.002	0.998	0.000
E41 Nutritional marasmus	0.002	0.998	0.000
E40 Kwashiorkor	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.998	0.000
J45.0 Predominantly allergic asthma	0.002	0.998	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.002	0.998	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.002	0.998	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.002	0.998	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M21.6 Other acquired deformities of ankle and foot	0.002	0.998	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.002	0.998	0.000
E63 Other nutritional deficiencies	0.002	0.998	0.000
E56 Other vitamin deficiencies	0.002	0.998	0.000
E51 Thiamine deficiency	0.002	0.998	0.000
E50 Vitamin A deficiency	0.002	0.998	0.000
E60 Dietary zinc deficiency	0.002	0.998	0.000
E59 Dietary selenium deficiency	0.002	0.998	0.000
E58 Dietary calcium deficiency	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations