TreeWAS – Variant ID: rs7012814

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I50.1 Left ventricular failure	0.426	0.574	0.000
I50.9 Heart failure, unspecified	0.419	0.581	0.000
I50 Heart failure	0.413	0.587	0.000
I50.0 Congestive heart failure	0.241	0.759	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.201	0.799	0.000
Z42 Follow-up care involving plastic surgery	0.045	0.955	0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.038	0.961	0.000
Z42.8 Follow-up care involving plastic surgery of other body part	0.037	0.963	0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.032	0.968	0.000
Z42.9 Follow-up care involving plastic surgery, unspecified	0.026	0.974	0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.025	0.974	0.000
G43.9 Migraine, unspecified	0.000	0.975	0.025
A63.0 Anogenital (venereal) warts	0.021	0.979	0.000
T43.2 Other and unspecified antidepressants	0.000	0.985	0.015
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.014	0.986	0.000
M75.0 Adhesive capsulitis of shoulder	0.000	0.987	0.013
N94.9 Unspecified condition associated with female genital organs and menstrual cycle	0.012	0.988	0.000
A63.8 Other specified predominantly sexually transmitted diseases	0.011	0.989	0.000
G43 Migraine	0.000	0.989	0.011
G96.0 Cerebrospinal fluid leak	0.000	0.990	0.010
R52.2 Other chronic pain	0.000	0.991	0.009
G43.1 Migraine with aura [classical migraine]	0.000	0.991	0.009
G43.3 Complicated migraine	0.000	0.991	0.009
G43.8 Other migraine	0.000	0.991	0.009
G43.2 Status migrainosus	0.000	0.992	0.008
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.992	0.008
H90 Conductive and sensorineural hearing loss	0.007	0.993	0.000
H90.3 Sensorineural hearing loss, bilateral	0.007	0.993	0.000
H90.5 Sensorineural hearing loss, unspecified	0.007	0.993	0.000
H90.2 Conductive hearing loss, unspecified	0.007	0.993	0.000
G43.0 Migraine without aura [common migraine]	0.000	0.993	0.007
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.007	0.993	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.006	0.993	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.994	0.006
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.006	0.994	0.000
H90.0 Conductive hearing loss, bilateral	0.006	0.994	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.006	0.994	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.006	0.994	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.005	0.995	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.995	0.005
A60 Anogenital herpesviral [herpes simplex] infections	0.005	0.995	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.005	0.995	0.001
T85.2 Mechanical complication of intraocular lens	0.005	0.995	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.005	0.995	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.005	0.995	0.000
A59 Trichomoniasis	0.005	0.995	0.000
A56 Other sexually transmitted chlamydial diseases	0.005	0.995	0.000
A54 Gonococcal infection	0.005	0.995	0.000
A53 Other and unspecified syphilis	0.005	0.995	0.000
A51 Early syphilis	0.005	0.995	0.000
A50 Congenital syphilis	0.005	0.995	0.000
A64 Unspecified sexually transmitted disease	0.005	0.995	0.000
A58 Granuloma inguinale	0.005	0.995	0.000
A57 Chancroid	0.005	0.995	0.000
A55 Chlamydial lymphogranuloma (venereum)	0.005	0.995	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.005	0.995	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.995	0.005
A52 Late syphilis	0.005	0.995	0.000
Z71.6 Tobacco abuse counselling	0.000	0.995	0.005
M31.6 Other giant cell arteritis	0.000	0.995	0.005
Z71.8 Other specified counselling	0.000	0.995	0.005
A60.0 Herpesviral infection of genitalia and urogenital tract	0.004	0.995	0.000
N94.6 Dysmenorrhoea, unspecified	0.005	0.995	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.005	0.995	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.995	0.004
M67.2 Synovial hypertrophy, not elsewhere classified	0.004	0.996	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.996	0.004
F40.2 Specific (isolated) phobias	0.004	0.996	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
A60.9 Anogenital herpesviral infection, unspecified	0.004	0.996	0.000
A60.1 Herpesviral infection of perianal skin and rectum	0.004	0.996	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.004	0.996	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.004	0.996	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.996	0.004
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.996	0.004
L71.9 Rosacea, unspecified	0.004	0.996	0.000
A50.9 Congenital syphilis, unspecified	0.004	0.996	0.000
A50.7 Late congenital syphilis, unspecified	0.004	0.996	0.000
A50.6 Late congenital syphilis, latent	0.004	0.996	0.000
A50.5 Other late congenital syphilis, symptomatic	0.004	0.996	0.000
A50.4 Late congenital neurosyphilis [juvenile neurosyphilis]	0.004	0.996	0.000
A50.3 Late congenital syphilitic oculopathy	0.004	0.996	0.000
A50.2 Early congenital syphilis, unspecified	0.004	0.996	0.000
A50.1 Early congenital syphilis, latent	0.004	0.996	0.000
A50.0 Early congenital syphilis, symptomatic	0.004	0.996	0.000
A51.9 Early syphilis, unspecified	0.004	0.996	0.000
A51.5 Early syphilis, latent	0.004	0.996	0.000
A51.4 Other secondary syphilis	0.004	0.996	0.000
A51.3 Secondary syphilis of skin and mucous membranes	0.004	0.996	0.000
A51.2 Primary syphilis of other sites	0.004	0.996	0.000
A51.1 Primary anal syphilis	0.004	0.996	0.000
A51.0 Primary genital syphilis	0.004	0.996	0.000
A53.9 Syphilis, unspecified	0.004	0.996	0.000
A53.0 Latent syphilis, unspecified as early or late	0.004	0.996	0.000
A54.9 Gonococcal infection, unspecified	0.004	0.996	0.000
A54.8 Other gonococcal infections	0.004	0.996	0.000
A54.6 Gonococcal infection of anus and rectum	0.004	0.996	0.000
A54.5 Gonococcal pharyngitis	0.004	0.996	0.000
A54.4 Gonococcal infection of musculoskeletal system	0.004	0.996	0.000
A54.3 Gonococcal infection of eye	0.004	0.996	0.000
A54.2 Gonococcal pelviperitonitis and other gonococcal genito-urinary infections	0.004	0.996	0.000
A54.1 Gonococcal infection of lower genito-urinary tract with periurethral and accessory gland abscess	0.004	0.996	0.000
A54.0 Gonococcal infection of lower genito-urinary tract without periurethral or accessory gland abscess	0.004	0.996	0.000
A56.8 Sexually transmitted chlamydial infection of other sites	0.004	0.996	0.000
A56.4 Chlamydial infection of pharynx	0.004	0.996	0.000
A56.3 Chlamydial infection of anus and rectum	0.004	0.996	0.000
A56.2 Chlamydial infection of genito-urinary tract, unspecified	0.004	0.996	0.000
A56.1 Chlamydial infection of pelviperitoneum and other genito-urinary organs	0.004	0.996	0.000
A56.0 Chlamydial infection of lower genito-urinary tract	0.004	0.996	0.000
A59.9 Trichomoniasis, unspecified	0.004	0.996	0.000
A59.8 Trichomoniasis of other sites	0.004	0.996	0.000
A59.0 Urogenital trichomoniasis	0.004	0.996	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.004	0.996	0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.004	0.996	0.000
A52.9 Late syphilis, unspecified	0.003	0.996	0.000
A52.8 Late syphilis, latent	0.003	0.996	0.000
A52.7 Other symptomatic late syphilis	0.003	0.996	0.000
A52.3 Neurosyphilis, unspecified	0.003	0.996	0.000
A52.2 Asymptomatic neurosyphilis	0.003	0.996	0.000
A52.0 Cardiovascular syphilis	0.003	0.996	0.000
G96 Other disorders of central nervous system	0.000	0.996	0.004
Z81.8 Family history of other mental and behavioural disorders	0.004	0.996	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.000	0.996	0.004
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.996	0.004
A52.1 Symptomatic neurosyphilis	0.003	0.996	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.996	0.003
N80.3 Endometriosis of pelvic peritoneum	0.004	0.996	0.000
Z95.1 Presence of aortocoronary bypass graft	0.004	0.996	0.000
N89.9 Noninflammatory disorder of vagina, unspecified	0.004	0.996	0.000
N17.9 Acute renal failure, unspecified	0.003	0.997	0.000
N94.5 Secondary dysmenorrhoea	0.003	0.997	0.000
N94.2 Vaginismus	0.003	0.997	0.000
N94.0 Mittelschmerz	0.003	0.997	0.000
N81.9 Female genital prolapse, unspecified	0.000	0.997	0.003
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.003	0.997	0.000
C48.2 Peritoneum, unspecified	0.003	0.997	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.003	0.997	0.000
T40.2 Other opioids	0.000	0.997	0.003
Z71.2 Person consulting for explanation of investigation findings	0.000	0.997	0.003
Z71.9 Counselling, unspecified	0.000	0.997	0.003
K91.3 Postoperative intestinal obstruction	0.000	0.997	0.003
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.003	0.997	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.003	0.997	0.000
N81.3 Complete uterovaginal prolapse	0.000	0.997	0.003
G96.9 Disorder of central nervous system, unspecified	0.000	0.997	0.003
Z71.7 Human immunodeficiency virus [HIV] counselling	0.000	0.997	0.003
Z71.5 Drug abuse counselling and surveillance	0.000	0.997	0.003
Z71.0 Person consulting on behalf of another person	0.000	0.997	0.003
O66 Other obstructed labour	0.000	0.997	0.003
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.997	0.003
N81.1 Cystocele	0.000	0.997	0.003
C48.1 Specified parts of peritoneum	0.003	0.997	0.000
N94.4 Primary dysmenorrhoea	0.003	0.997	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.003	0.997	0.000
G96.8 Other specified disorders of central nervous system	0.000	0.997	0.003
Z71.3 Dietary counselling and surveillance	0.000	0.997	0.003
Z71.4 Alcohol abuse counselling and surveillance	0.000	0.997	0.003
R44.0 Auditory hallucinations	0.003	0.997	0.000
N63 Unspecified lump in breast	0.003	0.997	0.000
M66.4 Spontaneous rupture of other tendons	0.003	0.997	0.000
O66.4 Failed trial of labour, unspecified	0.000	0.997	0.003
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.003	0.997	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
R44.1 Visual hallucinations	0.003	0.997	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.002	0.997	0.000
Z72.2 Drug use	0.003	0.997	0.000
R44.2 Other hallucinations	0.003	0.997	0.000
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.003	0.997	0.000
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.003	0.997	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.997	0.003
T51.9 Alcohol, unspecified	0.000	0.997	0.003
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.997	0.002
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.002	0.997	0.000
F40.9 Phobic anxiety disorder, unspecified	0.002	0.997	0.000
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.002	0.998	0.000
R44.3 Hallucinations, unspecified	0.002	0.998	0.000
N81 Female genital prolapse	0.000	0.998	0.002
F40 Phobic anxiety disorders	0.002	0.998	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.998	0.002
O66.9 Obstructed labour, unspecified	0.000	0.998	0.002
O66.8 Other specified obstructed labour	0.000	0.998	0.002
O66.3 Obstructed labour due to other abnormalities of foetus	0.000	0.998	0.002
O66.1 Obstructed labour due to locked twins	0.000	0.998	0.002
N62 Hypertrophy of breast	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.998	0.002
I05.1 Rheumatic mitral insufficiency	0.002	0.998	0.000
N81.6 Rectocele	0.000	0.998	0.002
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.002	0.998	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.998	0.002
I08.8 Other multiple valve diseases	0.002	0.998	0.000
M67 Other disorders of synovium and tendon	0.002	0.998	0.000
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.002	0.998	0.000
M66.48 Spontaneous rupture of other tendons (Other)	0.002	0.998	0.000
M66.44 Spontaneous rupture of other tendons (Hand)	0.002	0.998	0.000
M66.43 Spontaneous rupture of other tendons (Forearm)	0.002	0.998	0.000
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.002	0.998	0.000
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.002	0.998	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
J84 Other interstitial pulmonary diseases	0.002	0.998	0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.002	0.998	0.000
N81.5 Vaginal enterocele	0.000	0.998	0.002
C48.0 Retroperitoneum	0.002	0.998	0.000
I95.1 Orthostatic hypotension	0.002	0.998	0.000
K07.4 Malocclusion, unspecified	0.002	0.998	0.000
N17 Acute renal failure	0.002	0.998	0.000
D46.1 Refractory anaemia with sideroblasts	0.002	0.998	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.998	0.002
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
M66 Spontaneous rupture of synovium and tendon	0.002	0.998	0.000
N97.1 Female infertility of tubal origin	0.002	0.998	0.000
R45.1 Restlessness and agitation	0.000	0.998	0.002
N17.8 Other acute renal failure	0.002	0.998	0.000
O66.2 Obstructed labour due to unusually large foetus	0.000	0.998	0.002
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.002	0.998	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.002	0.998	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.998	0.002
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
F40.8 Other phobic anxiety disorders	0.002	0.998	0.000
K07.6 Temporomandibular joint disorders	0.002	0.998	0.000
T42.0 Hydantoin derivatives	0.000	0.998	0.002
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.998	0.002
N17.0 Acute renal failure with tubular necrosis	0.002	0.998	0.000
N71.1 Chronic inflammatory disease of uterus	0.002	0.998	0.000
F40.1 Social phobias	0.002	0.998	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.002	0.998	0.000
D46.2 Refractory anaemia with excess of blasts	0.002	0.998	0.000
M66.2 Spontaneous rupture of extensor tendons	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.998	0.002
T42.2 Succinimides and oxazolidinediones	0.000	0.998	0.002
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
T39.1 4-Aminophenol derivatives	0.000	0.998	0.002
L71 Rosacea	0.002	0.998	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.002	0.998	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.002	0.998	0.000
M67.3 Transient synovitis	0.002	0.998	0.000
M31 Other necrotising vasculopathies	0.000	0.998	0.002
M66.0 Rupture of popliteal cyst	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.998	0.002
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
J84.0 Alveolar and parietoalveolar conditions	0.002	0.998	0.000
N03.9 Unspecified	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
N17.2 Acute renal failure with medullary necrosis	0.002	0.998	0.000
M66.1 Rupture of synovium	0.002	0.998	0.000
N81.0 Female urethrocele	0.000	0.998	0.002
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.998	0.002
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.002	0.998	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.000	0.998	0.002
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.998	0.002
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.998	0.002
D46 Myelodysplastic syndromes	0.002	0.998	0.000
N60-N64 Disorders of breast	0.002	0.998	0.000
E89.0 Postprocedural hypothyroidism	0.002	0.998	0.000
J84.8 Other specified interstitial pulmonary diseases	0.002	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.998	0.002
T40.8 Lysergide [LSD]	0.000	0.998	0.002
T40.7 Cannabis (derivatives)	0.000	0.998	0.002
T40.3 Methadone	0.000	0.998	0.002
T40.0 Opium	0.000	0.998	0.002
T42.3 Barbiturates	0.000	0.998	0.002
S42.40 Fracture of lower end of humerus (closed)	0.000	0.998	0.002
M67.8 Other specified disorders of synovium and tendon	0.002	0.998	0.000
N81.2 Incomplete uterovaginal prolapse	0.000	0.998	0.002
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.002
N61 Inflammatory disorders of breast	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
M67.0 Short Achilles tendon (acquired)	0.002	0.998	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T42.4 Benzodiazepines	0.000	0.998	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.002
D46.9 Myelodysplastic syndrome, unspecified	0.002	0.998	0.000
D46.7 Other myelodysplastic syndromes	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
M66.06 Rupture of popliteal cyst-Lower leg	0.002	0.998	0.000
M31.9 Necrotising vasculopathy, unspecified	0.000	0.998	0.002
M66.3 Spontaneous rupture of flexor tendons	0.002	0.998	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
Z81 Family history of mental and behavioural disorders	0.002	0.998	0.000
F40.0 Agoraphobia	0.002	0.998	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.002	0.998	0.000
L71.1 Rhinophyma	0.002	0.998	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.002	0.998	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.002	0.998	0.000
S91.0 Open wound of ankle	0.000	0.998	0.002
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.998	0.001
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.001	0.998	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.001	0.998	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.001	0.998	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.001	0.998	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.001	0.998	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.001	0.998	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.001	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
I05.2 Mitral stenosis with insufficiency	0.002	0.998	0.000
I08.9 Multiple valve disease, unspecified	0.002	0.998	0.000
M31.3 Wegener's granulomatosis	0.000	0.998	0.002
M67.4 Ganglion	0.002	0.998	0.000
N64.4 Mastodynia	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.000	0.998	0.002
T39.2 Pyrazolone derivatives	0.000	0.998	0.002
T40.5 Cocaine	0.000	0.998	0.002
L71.0 Perioral dermatitis	0.002	0.998	0.000
M31.0 Hypersensitivity angiitis	0.000	0.998	0.002
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.000	0.998	0.002
R35 Polyuria	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.998	0.002
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.001	0.998	0.000
S32.10 Fracture of sacrum (closed)	0.002	0.998	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.998	0.002
M31.2 Lethal midline granuloma	0.000	0.998	0.002
M67.1 Other contracture of tendon (sheath)	0.002	0.998	0.000
B91 Sequelae of poliomyelitis	0.002	0.998	0.000
M66.09 Rupture of popliteal cyst-Site unspec	0.001	0.998	0.000
M66.08 Rupture of popliteal cyst-Other	0.001	0.998	0.000
M66.07 Rupture of popliteal cyst-Ankle/foot	0.001	0.998	0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.001	0.998	0.000
M66.04 Rupture of popliteal cyst-Hand	0.001	0.998	0.000
M66.03 Rupture of popliteal cyst-Forearm	0.001	0.998	0.000
M66.02 Rupture of popliteal cyst-Upper arm	0.001	0.998	0.000
M66.01 Rupture of popliteal cyst-Shldr region	0.001	0.998	0.000
M66.00 Rupture of popliteal cyst-Mult sites	0.001	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.000	0.998	0.002
D89.3 Immune reconstitution syndrome	0.001	0.998	0.000
M31.8 Other specified necrotising vasculopathies	0.000	0.998	0.002
T42.1 Iminostilbenes	0.000	0.998	0.001
I08 Multiple valve diseases	0.002	0.998	0.000
K05.6 Periodontal disease, unspecified	0.002	0.998	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.002	0.998	0.000
K70.1 Alcoholic hepatitis	0.002	0.998	0.000
M31.1 Thrombotic microangiopathy	0.000	0.998	0.001
M95.0 Acquired deformity of nose	0.000	0.998	0.002
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.001
T37.5 Antiviral drugs	0.000	0.998	0.001
T37.4 Anthelminthics	0.000	0.998	0.001
T37.3 Other antiprotozoal drugs	0.000	0.998	0.001
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.001
T37.1 Antimycobacterial drugs	0.000	0.998	0.001
T37.0 Sulphonamides	0.000	0.998	0.001
T40.1 Heroin	0.000	0.998	0.001
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.998	0.002
T88.7 Unspecified adverse effect of drug or medicament	0.002	0.998	0.000
M66.19 Rupture of synovium (Site unspecified)	0.001	0.998	0.000
M66.18 Rupture of synovium (Other)	0.001	0.998	0.000
M66.17 Rupture of synovium (Ankle and foot)	0.001	0.998	0.000
M66.16 Rupture of synovium (Lower leg)	0.001	0.998	0.000
M66.15 Rupture of synovium (Pelvic region and thigh)	0.001	0.998	0.000
M66.14 Rupture of synovium (Hand)	0.001	0.998	0.000
M66.13 Rupture of synovium (Forearm)	0.001	0.998	0.000
M66.12 Rupture of synovium (Upper arm)	0.001	0.998	0.000
M66.11 Rupture of synovium (Shoulder region)	0.001	0.998	0.000
M66.10 Rupture of synovium (Multiple sites)	0.001	0.998	0.000
I05 Rheumatic mitral valve diseases	0.002	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.998	0.001
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.001	0.998	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.001	0.998	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.001	0.998	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.001	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.998	0.000
L71.8 Other rosacea	0.001	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.001	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.998	0.001
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.001
T38.7 Androgens and anabolic congeners	0.000	0.998	0.001
T38.5 Other oestrogens and progestogens	0.000	0.998	0.001
T38.4 Oral contraceptives	0.000	0.998	0.001
T38.2 Antithyroid drugs	0.000	0.998	0.001
Z81.1 Family history of alcohol abuse	0.001	0.998	0.000
T36 Poisoning by systemic antibiotics	0.000	0.998	0.001
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.001	0.998	0.000
K07.9 Dentofacial anomaly, unspecified	0.001	0.998	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.002	0.998	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.998	0.001
N91.5 Oligomenorrhoea, unspecified	0.000	0.998	0.001
S01.1 Open wound of eyelid and periocular area	0.002	0.998	0.000
T41.5 Therapeutic gases	0.000	0.998	0.001
T41.4 Anaesthetic, unspecified	0.000	0.998	0.001
T41.3 Local anaesthetics	0.000	0.998	0.001
T41.2 Other and unspecified general anaesthetics	0.000	0.998	0.001
T41.1 Intravenous anaesthetics	0.000	0.998	0.001
T41.0 Inhaled anaesthetics	0.000	0.998	0.001
T59.8 Other specified gases, fumes and vapours	0.000	0.998	0.001
Y79.2 Prosthetic and other implants, materials and accessory devices	0.001	0.998	0.000
H01.8 Other specified inflammation of eyelid	0.000	0.998	0.002
K51.8 Other ulcerative colitis	0.002	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.001
T48.5 Anti-common-cold drugs	0.000	0.998	0.001
T48.4 Expectorants	0.000	0.998	0.001
T48.3 Antitussives	0.000	0.998	0.001
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.001
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.001
T48.0 Oxytocic drugs	0.000	0.998	0.001
Z44.8 Fitting and adjustment of other external prosthetic devices	0.001	0.998	0.000
Z81.4 Family history of other substance abuse	0.001	0.998	0.000
Z81.3 Family history of other psychoactive substance abuse	0.001	0.998	0.000
Z81.2 Family history of tobacco abuse	0.001	0.998	0.000
Z81.0 Family history of mental retardation	0.001	0.998	0.000
M65-M68 Disorders of synovium and tendon	0.002	0.998	0.000
M54.36 Sciatica (Lumbar region)	0.001	0.998	0.000
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.001	0.998	0.000
M66.38 Spontaneous rupture of flexor tendons (Other)	0.001	0.998	0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.001	0.998	0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.001	0.998	0.000
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.001	0.998	0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.001	0.998	0.000
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.001	0.998	0.000
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)	0.001	0.998	0.000
M66.58 Spontaneous rupture of unspecified tendon (Other)	0.001	0.998	0.000
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)	0.001	0.998	0.000
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)	0.001	0.998	0.000
M66.54 Spontaneous rupture of unspecified tendon (Hand)	0.001	0.998	0.000
M66.53 Spontaneous rupture of unspecified tendon (Forearm)	0.001	0.998	0.000
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)	0.001	0.998	0.000
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)	0.001	0.998	0.000
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)	0.001	0.998	0.000
D46.4 Refractory anaemia, unspecified	0.001	0.998	0.000
M67.49 Ganglion, multiple sites	0.001	0.999	0.000
M67.45 Ganglion, hip	0.001	0.999	0.000
T40.6 Other and unspecified narcotics	0.000	0.999	0.001
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.999	0.001
Q76 Congenital malformations of spine and bony thorax	0.001	0.999	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.999	0.001
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.999	0.001
T49.9 Topical agent, unspecified	0.000	0.999	0.001
T49.8 Other topical agents	0.000	0.999	0.001
T49.7 Dental drugs, topically applied	0.000	0.999	0.001
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.999	0.001
T49.5 Ophthalmological drugs and preparations	0.000	0.999	0.001
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.999	0.001
T49.3 Emollients, demulcents and protectants	0.000	0.999	0.001
T49.2 Local astringents and local detergents	0.000	0.999	0.001
T49.1 Antipruritics	0.000	0.999	0.001
W27.6 Industrial and construction area	0.000	0.999	0.001
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.001	0.999	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.001	0.999	0.000
T36.3 Macrolides	0.000	0.999	0.001
T38.1 Thyroid hormones and substitutes	0.000	0.999	0.001
T38.0 Glucocorticoids and synthetic analogues	0.000	0.999	0.001
M31.7 Microscopic polyangiitis	0.000	0.999	0.001
Z71.1 Person with feared complaint in whom no diagnosis is made	0.000	0.999	0.001
I60 Subarachnoid haemorrhage	0.000	0.999	0.001
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.999	0.001
A04.5 Campylobacter enteritis	0.000	0.999	0.001
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.000	0.999	0.001
N64.3 Galactorrhoea not associated with childbirth	0.001	0.999	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.001	0.999	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.000	0.999	0.001
I05.8 Other mitral valve diseases	0.001	0.999	0.000
K07.8 Other dentofacial anomalies	0.001	0.999	0.000
N94.3 Premenstrual tension syndrome	0.001	0.999	0.001
O41.0 Oligohydramnios	0.001	0.999	0.000
T36.4 Tetracyclines	0.000	0.999	0.001
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.999	0.001
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.999	0.001
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.999	0.001
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.999	0.001
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.999	0.001
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.999	0.001
T44.0 Anticholinesterase agents	0.000	0.999	0.001
N64 Other disorders of breast	0.001	0.999	0.000
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.001	0.999	0.000
C92.0 Acute myeloid leukaemia	0.001	0.999	0.000
I27.9 Pulmonary heart disease, unspecified	0.001	0.999	0.000
Q61.3 Polycystic kidney, unspecified	0.001	0.999	0.000
S91.3 Open wound of other parts of foot	0.000	0.999	0.001
H71 Cholesteatoma of middle ear	0.000	0.999	0.001
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)	0.001	0.999	0.000
S91.2 Open wound of toe(s) with damage to nail	0.000	0.999	0.001
T36.9 Systemic antibiotic, unspecified	0.000	0.999	0.001
T36.7 Antifungal antibiotics, systemically used	0.000	0.999	0.001
T36.6 Rifamycins	0.000	0.999	0.001
T36.5 Aminoglycosides	0.000	0.999	0.001
T36.2 Chloramphenicol group	0.000	0.999	0.001
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.999	0.001
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.999	0.001
Z04.8 Examination and observation for other specified reasons	0.001	0.999	0.000
K07 Dentofacial anomalies [including malocclusion]	0.001	0.999	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.001	0.999	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.001	0.999	0.000
M67.47 Ganglion, ankle and foot	0.001	0.999	0.000
D11.9 Major salivary gland, unspecified	0.001	0.999	0.000
F60.3 Emotionally unstable personality disorder	0.000	0.999	0.001
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.999	0.001
I82.8 Embolism and thrombosis of other specified veins	0.001	0.999	0.000
T40.4 Other synthetic narcotics	0.000	0.999	0.001
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.001	0.999	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.999	0.001
M67.43 Ganglion, wrist	0.001	0.999	0.000
L13.0 Dermatitis herpetiformis	0.001	0.999	0.000
M14.6 Neuropathic arthropathy	0.001	0.999	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations