TreeWAS – Variant ID: rs7042950

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.857	0.143
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.858	0.142
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.865	0.135
T42.4 Benzodiazepines	0.000	0.867	0.133
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.868	0.132
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.868	0.132
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.873	0.126
T42.1 Iminostilbenes	0.000	0.874	0.126
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.882	0.118
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.887	0.113
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.891	0.108
T42.0 Hydantoin derivatives	0.000	0.892	0.108
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.897	0.103
T42.2 Succinimides and oxazolidinediones	0.000	0.897	0.103
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.898	0.102
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.899	0.101
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.901	0.099
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.901	0.099
T43.9 Psychotropic drug, unspecified	0.000	0.903	0.097
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.903	0.097
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.903	0.097
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.903	0.097
T43.2 Other and unspecified antidepressants	0.000	0.904	0.096
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.905	0.095
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.905	0.095
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.905	0.095
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.906	0.094
T42.3 Barbiturates	0.000	0.911	0.089
T36 Poisoning by systemic antibiotics	0.000	0.911	0.089
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.913	0.087
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.914	0.086
T46.1 Calcium-channel blockers	0.000	0.915	0.085
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.916	0.084
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.916	0.084
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.916	0.084
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.916	0.084
T43.6 Psychostimulants with abuse potential	0.000	0.917	0.082
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.918	0.082
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.918	0.082
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.918	0.081
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.918	0.081
T46.7 Peripheral vasodilators	0.000	0.918	0.081
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.918	0.081
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.918	0.081
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.919	0.081
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.924	0.076
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.927	0.073
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.927	0.073
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.927	0.073
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.927	0.073
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.927	0.073
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.927	0.073
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.927	0.073
T44.0 Anticholinesterase agents	0.000	0.927	0.073
T50.7 Analeptics and opioid receptor antagonists	0.000	0.928	0.072
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.928	0.072
T50.5 Appetite depressants	0.000	0.928	0.072
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.928	0.072
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.928	0.072
T50.1 Loop [high-ceiling] diuretics	0.000	0.928	0.072
T50.0 Mineralocorticoids and their antagonists	0.000	0.928	0.072
T50.8 Diagnostic agents	0.000	0.928	0.071
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.929	0.071
T38.9 Other and unspecified hormone antagonists	0.000	0.929	0.071
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.929	0.071
T38.7 Androgens and anabolic congeners	0.000	0.929	0.071
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.929	0.071
T38.5 Other oestrogens and progestogens	0.000	0.929	0.071
T38.4 Oral contraceptives	0.000	0.929	0.071
T38.2 Antithyroid drugs	0.000	0.929	0.071
T38.0 Glucocorticoids and synthetic analogues	0.000	0.929	0.071
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.929	0.071
T45.0 Antiallergic and antiemetic drugs	0.000	0.930	0.070
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.930	0.069
T37.5 Antiviral drugs	0.000	0.930	0.069
T37.4 Anthelminthics	0.000	0.930	0.069
T37.3 Other antiprotozoal drugs	0.000	0.930	0.069
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.930	0.069
T37.1 Antimycobacterial drugs	0.000	0.930	0.069
T37.0 Sulphonamides	0.000	0.930	0.069
T50.4 Drugs affecting uric acid metabolism	0.000	0.931	0.069
T41.5 Therapeutic gases	0.000	0.932	0.068
T41.4 Anaesthetic, unspecified	0.000	0.932	0.068
T41.3 Local anaesthetics	0.000	0.932	0.068
T41.2 Other and unspecified general anaesthetics	0.000	0.932	0.068
T41.1 Intravenous anaesthetics	0.000	0.932	0.068
T41.0 Inhaled anaesthetics	0.000	0.932	0.068
T49.9 Topical agent, unspecified	0.000	0.932	0.068
T49.8 Other topical agents	0.000	0.932	0.068
T49.7 Dental drugs, topically applied	0.000	0.932	0.068
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.932	0.068
T49.5 Ophthalmological drugs and preparations	0.000	0.932	0.068
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.932	0.068
T49.3 Emollients, demulcents and protectants	0.000	0.932	0.068
T49.2 Local astringents and local detergents	0.000	0.932	0.068
T49.1 Antipruritics	0.000	0.932	0.068
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.932	0.068
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.932	0.068
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.932	0.068
T47.7 Emetics	0.000	0.932	0.068
T47.6 Antidiarrhoeal drugs	0.000	0.932	0.068
T47.5 Digestants	0.000	0.932	0.068
T47.4 Other laxatives	0.000	0.932	0.068
T47.3 Saline and osmotic laxatives	0.000	0.932	0.068
T47.2 Stimulant laxatives	0.000	0.932	0.068
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.932	0.068
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.933	0.067
T48.5 Anti-common-cold drugs	0.000	0.933	0.067
T48.4 Expectorants	0.000	0.933	0.067
T48.3 Antitussives	0.000	0.933	0.067
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.933	0.067
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.933	0.067
T48.0 Oxytocic drugs	0.000	0.933	0.067
T40.4 Other synthetic narcotics	0.000	0.933	0.067
T40.6 Other and unspecified narcotics	0.000	0.933	0.067
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.934	0.066
T47.0 Histamine H(2)-receptor antagonists	0.000	0.936	0.064
T36.9 Systemic antibiotic, unspecified	0.000	0.936	0.064
T36.8 Other systemic antibiotics	0.000	0.936	0.064
T36.7 Antifungal antibiotics, systemically used	0.000	0.936	0.064
T36.6 Rifamycins	0.000	0.936	0.064
T36.5 Aminoglycosides	0.000	0.936	0.064
T36.4 Tetracyclines	0.000	0.936	0.064
T36.3 Macrolides	0.000	0.936	0.064
T36.2 Chloramphenicol group	0.000	0.936	0.064
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.936	0.064
T45.2 Vitamins, not elsewhere classified	0.000	0.939	0.061
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.939	0.060
T45.8 Other primarily systemic and haematological agents	0.000	0.939	0.060
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.939	0.060
T45.6 Fibrinolysis-affecting drugs	0.000	0.939	0.060
T45.4 Iron and its compounds	0.000	0.939	0.060
T45.3 Enzymes, not elsewhere classified	0.000	0.939	0.060
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.940	0.060
T40.8 Lysergide [LSD]	0.000	0.940	0.060
T40.7 Cannabis (derivatives)	0.000	0.940	0.060
T40.3 Methadone	0.000	0.940	0.060
T40.1 Heroin	0.000	0.940	0.060
T40.0 Opium	0.000	0.940	0.060
T38.1 Thyroid hormones and substitutes	0.000	0.940	0.060
T36.0 Penicillins	0.000	0.942	0.058
T40.5 Cocaine	0.000	0.942	0.058
T45.5 Anticoagulants	0.000	0.946	0.054
T45.1 Antineoplastic and immunosuppressive drugs	0.001	0.962	0.038
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.966	0.034
S82.00 Fracture of patella (closed)	0.031	0.969	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.974	0.026
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.975	0.025
T39.4 Antirheumatics, not elsewhere classified	0.000	0.975	0.025
T39.2 Pyrazolone derivatives	0.000	0.975	0.025
T40.2 Other opioids	0.000	0.979	0.021
T39.0 Salicylates	0.000	0.980	0.020
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.982	0.018
O36.8 Maternal care for other specified foetal problems	0.000	0.983	0.017
J43.9 Emphysema, unspecified	0.000	0.985	0.015
S82.0 Fracture of patella	0.015	0.985	0.000
S82.01 Fracture of patella (open)	0.011	0.989	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.011	0.989	0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.011	0.989	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.990	0.009
S92.0 Fracture of calcaneus	0.000	0.992	0.008
F33.9 Recurrent depressive disorder, unspecified	0.000	0.992	0.008
S92 Fracture of foot, except ankle	0.000	0.992	0.008
S92.2 Fracture of other tarsal bone(s)	0.000	0.992	0.007
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.992	0.007
S92.1 Fracture of talus	0.000	0.993	0.007
M25.6 Stiffness of joint, not elsewhere classified	0.007	0.993	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.007	0.993	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.007	0.993	0.000
C71.9 Brain, unspecified	0.007	0.993	0.000
S92.10 Fracture of talus (closed)	0.000	0.993	0.007
S92.01 Fracture of calcaneus (open)	0.000	0.994	0.006
S92.7 Multiple fractures of foot	0.000	0.994	0.006
S92.4 Fracture of great toe	0.000	0.994	0.006
J43 Emphysema	0.000	0.994	0.006
F33 Recurrent depressive disorder	0.000	0.994	0.006
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.994	0.006
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.006	0.994	0.000
F43.9 Reaction to severe stress, unspecified	0.000	0.994	0.006
S92.9 Fracture of foot, unspecified	0.000	0.994	0.006
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.994	0.006
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.994	0.006
C71 Malignant neoplasm of brain	0.006	0.994	0.000
J30.1 Allergic rhinitis due to pollen	0.000	0.994	0.006
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.994	0.006
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.006	0.994	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.994	0.006
D89.2 Hypergammaglobulinaemia, unspecified	0.006	0.994	0.000
C71.2 Temporal lobe	0.006	0.994	0.000
S92.41 Fracture of great toe (open)	0.000	0.995	0.005
S92.11 Fracture of talus (open)	0.000	0.995	0.005
S92.5 Fracture of other toe	0.000	0.995	0.005
C71.0 Cerebrum, except lobes and ventricles	0.005	0.995	0.000
S92.3 Fracture of metatarsal bone	0.000	0.995	0.005
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.995	0.005
S92.70 Multiple fractures of foot (closed)	0.000	0.995	0.005
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.005	0.995	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
J30.3 Other allergic rhinitis	0.000	0.995	0.005
E66.8 Other obesity	0.005	0.995	0.000
J30 Vasomotor and allergic rhinitis	0.000	0.995	0.005
F43.0 Acute stress reaction	0.000	0.995	0.005
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.005	0.995	0.000
C71.8 Overlapping lesion of brain	0.005	0.995	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.005	0.995	0.000
J43.8 Other emphysema	0.000	0.995	0.005
F43 Reaction to severe stress, and adjustment disorders	0.000	0.995	0.005
S92.71 Multiple fractures of foot (open)	0.000	0.995	0.005
I08.1 Disorders of both mitral and tricuspid valves	0.005	0.995	0.000
J43.1 Panlobular emphysema	0.000	0.995	0.005
J43.0 MacLeod's syndrome	0.000	0.995	0.005
C43 Malignant melanoma of skin	0.000	0.995	0.005
C71.3 Parietal lobe	0.005	0.995	0.000
J30.4 Allergic rhinitis, unspecified	0.000	0.995	0.005
F33.8 Other recurrent depressive disorders	0.000	0.995	0.005
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.995	0.005
J13 Pneumonia due to Streptococcus pneumoniae	0.005	0.995	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.004	0.995	0.000
S92.40 Fracture of great toe (closed)	0.000	0.995	0.004
S92.91 Fracture of foot, unspecified (open)	0.000	0.995	0.004
S92.90 Fracture of foot, unspecified (closed)	0.000	0.995	0.004
C71.7 Brain stem	0.004	0.996	0.000
C71.6 Cerebellum	0.004	0.996	0.000
C71.5 Cerebral ventricle	0.004	0.996	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.996	0.004
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.004	0.996	0.000
F43.1 Posttraumatic stress disorder	0.000	0.996	0.004
C43.9 Malignant melanoma of skin, unspecified	0.000	0.996	0.004
S92.50 Fracture of other toe (closed)	0.000	0.996	0.004
C71.4 Occipital lobe	0.004	0.996	0.000
S92.31 Fracture of metatarsal bone (open)	0.000	0.996	0.004
J30.0 Vasomotor rhinitis	0.000	0.996	0.004
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.996	0.004
C67.3 Anterior wall of bladder	0.000	0.996	0.004
I74.5 Embolism and thrombosis of iliac artery	0.004	0.996	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.000	0.996	0.004
J30.2 Other seasonal allergic rhinitis	0.000	0.996	0.004
C43.5 Malignant melanoma of trunk	0.000	0.996	0.004
C67.2 Lateral wall of bladder	0.000	0.996	0.004
C71.1 Frontal lobe	0.004	0.996	0.000
F43.8 Other reactions to severe stress	0.000	0.996	0.004
C43.8 Overlapping malignant melanoma of skin	0.000	0.996	0.004
C43.0 Malignant melanoma of lip	0.000	0.996	0.004
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.996	0.004
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.996	0.004
T39.1 4-Aminophenol derivatives	0.000	0.996	0.004
S90-S99 Injuries to the ankle and foot	0.000	0.996	0.004
K76.6 Portal hypertension	0.000	0.996	0.004
J43.2 Centrilobular emphysema	0.000	0.996	0.003
M79.28 Neuralgia and neuritis, unspecified (Other)	0.000	0.996	0.004
C67 Malignant neoplasm of bladder	0.000	0.996	0.004
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.997	0.003
S92.51 Fracture of other toe (open)	0.000	0.997	0.003
S92.30 Fracture of metatarsal bone (closed)	0.000	0.997	0.003
F43.2 Adjustment disorders	0.000	0.997	0.003
E66.2 Extreme obesity with alveolar hypoventilation	0.003	0.997	0.000
C67.1 Dome of bladder	0.000	0.997	0.003
K07.6 Temporomandibular joint disorders	0.003	0.997	0.000
K31.7 Polyp of stomach and duodenum	0.003	0.997	0.000
C67.0 Trigone of bladder	0.000	0.997	0.003
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.997	0.003
I95.9 Hypotension, unspecified	0.003	0.997	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.997	0.003
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.000	0.997	0.003
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.997	0.003
E66 Obesity	0.003	0.997	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.997	0.003
C67.4 Posterior wall of bladder	0.000	0.997	0.003
C43.4 Malignant melanoma of scalp and neck	0.000	0.997	0.003
J46 Status asthmaticus	0.000	0.997	0.003
K74.3 Primary biliary cirrhosis	0.000	0.997	0.003
M79.2 Neuralgia and neuritis, unspecified	0.000	0.997	0.003
S90 Superficial injury of ankle and foot	0.000	0.997	0.003
I78.1 Naevus, nonneoplastic	0.000	0.997	0.003
J40 Bronchitis, not specified as acute or chronic	0.000	0.997	0.003
K74 Fibrosis and cirrhosis of liver	0.000	0.997	0.003
S98 Traumatic amputation of ankle and foot	0.000	0.997	0.003
S97 Crushing injury of ankle and foot	0.000	0.997	0.003
S95 Injury of blood vessels at ankle and foot level	0.000	0.997	0.003
S94 Injury of nerves at ankle and foot level	0.000	0.997	0.003
D21.2 Connective and other soft tissue of lower limb, including hip	0.000	0.997	0.003
C67.8 Overlapping lesion of bladder	0.000	0.997	0.003
C67.7 Urachus	0.000	0.997	0.003
F31.0 Bipolar affective disorder, current episode hypomanic	0.003	0.997	0.000
S93.1 Dislocation of toe(s)	0.000	0.997	0.003
K74.5 Biliary cirrhosis, unspecified	0.000	0.997	0.003
D21 Other benign neoplasms of connective and other soft tissue	0.000	0.997	0.003
I95.1 Orthostatic hypotension	0.003	0.997	0.000
K76.9 Liver disease, unspecified	0.000	0.997	0.003
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.997	0.002
M54.36 Sciatica (Lumbar region)	0.003	0.997	0.000
C67.5 Bladder neck	0.000	0.997	0.003
J14 Pneumonia due to Haemophilus influenzae	0.003	0.997	0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.000	0.997	0.003
S90.8 Other superficial injuries of ankle and foot	0.000	0.997	0.003
J12.1 Respiratory syncytial virus pneumonia	0.003	0.997	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.997	0.000
D89.3 Immune reconstitution syndrome	0.002	0.997	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.997	0.003
J12 Viral pneumonia, not elsewhere classified	0.003	0.997	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.997	0.002
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.997	0.002
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.997	0.002
S91.1 Open wound of toe(s) without damage to nail	0.000	0.997	0.002
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.997	0.002
S91 Open wound of ankle and foot	0.000	0.997	0.002
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.000	0.997	0.002
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.000	0.997	0.002
E66.1 Drug-induced obesity	0.002	0.997	0.000
E66.0 Obesity due to excess calories	0.002	0.997	0.000
S93.4 Sprain and strain of ankle	0.000	0.997	0.002
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.997	0.002
S93.5 Sprain and strain of toe(s)	0.000	0.997	0.002
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.997	0.002
K76 Other diseases of liver	0.000	0.997	0.003
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.002	0.998	0.000
K74.0 Hepatic fibrosis	0.000	0.998	0.002
L65.9 Nonscarring hair loss, unspecified	0.002	0.998	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.998	0.002
S93.0 Dislocation of ankle joint	0.000	0.998	0.002
I08 Multiple valve diseases	0.002	0.998	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.002	0.998	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.002	0.998	0.000
D21.5 Connective and other soft tissue of pelvis	0.000	0.998	0.002
I08.9 Multiple valve disease, unspecified	0.002	0.998	0.000
S90.0 Contusion of ankle	0.000	0.998	0.002
J12.9 Viral pneumonia, unspecified	0.002	0.998	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.998	0.002
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.000	0.998	0.002
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.000	0.998	0.002
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.000	0.998	0.002
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.000	0.998	0.002
C67.6 Ureteric orifice	0.000	0.998	0.002
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.998	0.002
S90.2 Contusion of toe(s) with damage to nail	0.000	0.998	0.002
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
E55.9 Vitamin D deficiency, unspecified	0.002	0.998	0.000
G61.0 Guillain-Barre syndrome	0.000	0.998	0.002
K74.4 Secondary biliary cirrhosis	0.000	0.998	0.002
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.998	0.002
K74.1 Hepatic sclerosis	0.000	0.998	0.002
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.998	0.002
S99 Other and unspecified injuries of ankle and foot	0.000	0.998	0.002
M54.37 Sciatica (Lumbosacral region)	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.998	0.002
S94.8 Injury of other nerves at ankle and foot level	0.000	0.998	0.002
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.998	0.002
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.998	0.002
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.998	0.002
S94.1 Injury of medial plantar nerve	0.000	0.998	0.002
S94.0 Injury of lateral plantar nerve	0.000	0.998	0.002
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.998	0.002
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.998	0.002
S95.7 Injury of multiple blood vessels at ankle and foot level	0.000	0.998	0.002
S95.2 Injury of dorsal vein of foot	0.000	0.998	0.002
S95.1 Injury of plantar artery of foot	0.000	0.998	0.002
S95.0 Injury of dorsal artery of foot	0.000	0.998	0.002
S97.8 Crushing injury of other parts of ankle and foot	0.000	0.998	0.002
S97.1 Crushing injury of toe(s)	0.000	0.998	0.002
S97.0 Crushing injury of ankle	0.000	0.998	0.002
S98.4 Traumatic amputation of foot, level unspecified	0.000	0.998	0.002
S98.3 Traumatic amputation of other parts of foot	0.000	0.998	0.002
S98.2 Traumatic amputation of two or more toes	0.000	0.998	0.002
S98.1 Traumatic amputation of one toe	0.000	0.998	0.002
S98.0 Traumatic amputation of foot at ankle level	0.000	0.998	0.002
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.998	0.002
J09-J18 Influenza and pneumonia	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.998	0.002
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
D21.9 Connective and other soft tissue, unspecified	0.000	0.998	0.002
D84 Other immunodeficiencies	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.002	0.998	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M25.9 Joint disorder, unspecified	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.000	0.998	0.002
H46 Optic neuritis	0.002	0.998	0.000
D21.6 Connective and other soft tissue of trunk, unspecified	0.000	0.998	0.002
D21.3 Connective and other soft tissue of thorax	0.000	0.998	0.002
M48.02 Spinal stenosis (Cervical region)	0.002	0.998	0.000
K75.0 Abscess of liver	0.000	0.998	0.002
M54.3 Sciatica	0.002	0.998	0.000
D21.4 Connective and other soft tissue of abdomen	0.000	0.998	0.002
C70 Malignant neoplasm of meninges	0.002	0.998	0.000
J17 Pneumonia in diseases classified elsewhere	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.998	0.002
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.998	0.002
J40-J47 Chronic lower respiratory diseases	0.000	0.998	0.002
S90.3 Contusion of other and unspecified parts of foot	0.000	0.998	0.002
C70.0 Cerebral meninges	0.002	0.998	0.000
I49.8 Other specified cardiac arrhythmias	0.002	0.998	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.000	0.998	0.002
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
J12.8 Other viral pneumonia	0.002	0.998	0.000
J12.3 Human metapneumovirus pneumonia	0.002	0.998	0.000
J12.2 Parainfluenza virus pneumonia	0.002	0.998	0.000
J12.0 Adenoviral pneumonia	0.002	0.998	0.000
K76.1 Chronic passive congestion of liver	0.000	0.998	0.002
M25.93 Joint disorder, unspecified (Forearm)	0.002	0.998	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.002	0.998	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.000	0.998	0.002
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.998	0.002
M25.99 Joint disorder, unspecified (Site unspecified)	0.002	0.998	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
S93.40 Sprain of unspecified ligament of ankle	0.000	0.998	0.002
D35.0 Adrenal gland	0.002	0.998	0.000
K76.5 Hepatic veno-occlusive disease	0.000	0.998	0.002
K76.4 Peliosis hepatis	0.000	0.998	0.002
K76.3 Infarction of liver	0.000	0.998	0.002
K76.2 Central haemorrhagic necrosis of liver	0.000	0.998	0.002
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.998	0.002
M25.94 Joint disorder, unspecified (Hand)	0.002	0.998	0.000
I95 Hypotension	0.002	0.998	0.000
K70-K77 Diseases of liver	0.000	0.998	0.002
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
K26.3 Acute without haemorrhage or perforation	0.000	0.998	0.002
K72 Hepatic failure, not elsewhere classified	0.000	0.998	0.002
M54.30 Sciatica (Multiple sites in spine)	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
N97.9 Female infertility, unspecified	0.000	0.998	0.002
Z72.2 Drug use	0.000	0.998	0.002
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.002	0.998	0.000
S61 Open wound of wrist and hand	0.000	0.998	0.002
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.002	0.998	0.000
S91.0 Open wound of ankle	0.000	0.998	0.002
S91.2 Open wound of toe(s) with damage to nail	0.000	0.998	0.002
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.998	0.002
G04.1 Tropical spastic paraplegia	0.000	0.998	0.002
G04.0 Acute disseminated encephalitis	0.000	0.998	0.002
S99.7 Multiple injuries of ankle and foot	0.000	0.998	0.002
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.002	0.998	0.000
J09 Influenza due to certain identified influenza virus	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
H34.2 Other retinal artery occlusions	0.000	0.998	0.002
K72.9 Hepatic failure, unspecified	0.000	0.998	0.002
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.002	0.998	0.000
M25.98 Joint disorder, unspecified (Other)	0.002	0.998	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.002	0.998	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
D84.1 Defects in the complement system	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.998	0.002
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.002	0.998	0.000
S41.1 Open wound of upper arm	0.002	0.998	0.000
J41 Simple and mucopurulent chronic bronchitis	0.000	0.998	0.002
A48.1 Legionnaires' disease	0.002	0.998	0.000
M54.39 Sciatica (Site unspecified)	0.002	0.998	0.000
M54.35 Sciatica (Thoracolumbar region)	0.002	0.998	0.000
M54.34 Sciatica-Thoracic	0.002	0.998	0.000
M54.33 Sciatica-Cervicothoracic	0.002	0.998	0.000
M54.32 Sciatica-Cervical	0.002	0.998	0.000
M54.31 Sciatica-Occipit-atl-axl	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
K72.0 Acute and subacute hepatic failure	0.000	0.998	0.002
C70.9 Meninges, unspecified	0.002	0.998	0.000
C70.1 Spinal meninges	0.002	0.998	0.000
J17.8 Pneumonia in other diseases classified elsewhere	0.002	0.998	0.000
K76.7 Hepatorenal syndrome	0.000	0.998	0.002
J11 Influenza, virus not identified	0.002	0.998	0.000
K07.9 Dentofacial anomaly, unspecified	0.002	0.998	0.000
T51.9 Alcohol, unspecified	0.000	0.998	0.002
I08.2 Disorders of both aortic and tricuspid valves	0.002	0.998	0.000
I83 Varicose veins of lower extremities	0.002	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.998	0.002
J17.2 Pneumonia in mycoses	0.002	0.998	0.000
J17.1 Pneumonia in viral diseases classified elsewhere	0.002	0.998	0.000
S61.0 Open wound of finger(s) without damage to nail	0.000	0.998	0.002
S99.8 Other specified injuries of ankle and foot	0.000	0.998	0.002
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.002	0.998	0.000
H81.0 Meniere's disease	0.002	0.998	0.000
K77 Liver disorders in diseases classified elsewhere	0.000	0.998	0.002
K71 Toxic liver disease	0.000	0.998	0.002
M79.54 Residual foreign body in soft tissue (Hand)	0.000	0.998	0.002
F31.6 Bipolar affective disorder, current episode mixed	0.002	0.998	0.000
I08.8 Other multiple valve diseases	0.002	0.998	0.000
N85.0 Endometrial glandular hyperplasia	0.002	0.998	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.001	0.998	0.000
D81.8 Other combined immunodeficiencies	0.001	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations