TreeWAS – Variant ID: rs705145

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M25.46 Effusion of joint (Lower leg)	0.058	0.942	0.000
M47.86 Other spondylosis (Lumbar region)	0.056	0.944	0.000
M25.4 Effusion of joint	0.048	0.952	0.000
M25.42 Effusion of joint (Upper arm)	0.044	0.956	0.000
M25.40 Effusion of joint (Multiple sites)	0.040	0.960	0.000
M25.43 Effusion of joint (Forearm)	0.036	0.964	0.000
M25.49 Effusion of joint (Site unspecified)	0.035	0.965	0.000
M25.48 Effusion of joint (Other)	0.035	0.965	0.000
M25.47 Effusion of joint (Ankle and foot)	0.034	0.966	0.000
M25.41 Effusion of joint (Shoulder region)	0.033	0.967	0.000
M25 Other joint disorders, not elsewhere classified	0.032	0.968	0.000
M25.44 Effusion of joint (Hand)	0.031	0.969	0.000
M25.0 Haemarthrosis	0.028	0.972	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.027	0.973	0.000
M25.76 Osteophyte (Lower leg)	0.027	0.973	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.027	0.973	0.000
M25.06 Haemarthrosis (Lower leg)	0.026	0.974	0.000
M25.9 Joint disorder, unspecified	0.025	0.975	0.000
M25.7 Osteophyte	0.025	0.975	0.000
M25.8 Other specified joint disorders	0.025	0.975	0.000
M25.2 Flail joint	0.023	0.977	0.000
M25.1 Fistula of joint	0.023	0.977	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.022	0.978	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.022	0.978	0.000
M25.86 Other specified joint disorders (Lower leg)	0.022	0.978	0.000
M25.79 Osteophyte (Site unspecified)	0.021	0.979	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.021	0.979	0.000
M25.09 Haemarthrosis (Site unspecified)	0.021	0.979	0.000
M25.08 Haemarthrosis (Other)	0.021	0.979	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.021	0.979	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.021	0.979	0.000
M25.04 Haemarthrosis (Hand)	0.021	0.979	0.000
M25.03 Haemarthrosis (Forearm)	0.021	0.979	0.000
M25.02 Haemarthrosis (Upper arm)	0.021	0.979	0.000
M25.01 Haemarthrosis (Shoulder region)	0.021	0.979	0.000
M25.00 Haemarthrosis (Multiple sites)	0.021	0.979	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.021	0.979	0.000
M25.98 Joint disorder, unspecified (Other)	0.021	0.979	0.000
M25.94 Joint disorder, unspecified (Hand)	0.020	0.980	0.000
M25.3 Other instability of joint	0.020	0.980	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.020	0.980	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.020	0.980	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.019	0.981	0.000
M25.83 Other specified joint disorders (Forearm)	0.019	0.981	0.000
M25.82 Other specified joint disorders (Upper arm)	0.019	0.981	0.000
M47.8 Other spondylosis	0.019	0.981	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.019	0.981	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.019	0.981	0.000
M25.84 Other specified joint disorders (Hand)	0.019	0.981	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.019	0.981	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.018	0.982	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.018	0.982	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.018	0.982	0.000
M25.70 Osteophyte (Multiple sites)	0.018	0.982	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.018	0.982	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.018	0.982	0.000
M25.73 Osteophyte (Forearm)	0.018	0.982	0.000
M25.78 Osteophyte (Other)	0.018	0.982	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.018	0.982	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.018	0.982	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.017	0.983	0.000
M25.19 Fistula of joint (Site unspecified)	0.017	0.983	0.000
M25.18 Fistula of joint (Other)	0.017	0.983	0.000
M25.17 Fistula of joint (Ankle and foot)	0.017	0.983	0.000
M25.16 Fistula of joint (Lower leg)	0.017	0.983	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.017	0.983	0.000
M25.14 Fistula of joint (Hand)	0.017	0.983	0.000
M25.13 Fistula of joint (Forearm)	0.017	0.983	0.000
M25.12 Fistula of joint (Upper arm)	0.017	0.983	0.000
M25.11 Fistula of joint (Shoulder region)	0.017	0.983	0.000
M25.10 Fistula of joint (Multiple sites)	0.017	0.983	0.000
M25.29 Flail joint (Site unspecified)	0.017	0.983	0.000
M25.28 Flail joint (Other)	0.017	0.983	0.000
M25.27 Flail joint (Ankle and foot)	0.017	0.983	0.000
M25.26 Flail joint (Lower leg)	0.017	0.983	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.017	0.983	0.000
M25.24 Flail joint (Hand)	0.017	0.983	0.000
M25.23 Flail joint (Forearm)	0.017	0.983	0.000
M25.22 Flail joint (Upper arm)	0.017	0.983	0.000
M25.21 Flail joint (Shoulder region)	0.017	0.983	0.000
M25.20 Flail joint (Multiple sites)	0.017	0.983	0.000
M25.31 Other instability of joint (Shoulder region)	0.017	0.983	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.016	0.983	0.000
M25.74 Osteophyte (Hand)	0.016	0.984	0.000
M25.36 Other instability of joint (Lower leg)	0.016	0.984	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.016	0.984	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.016	0.984	0.000
M47 Spondylosis	0.016	0.984	0.000
M22.2 Patellofemoral disorders	0.015	0.985	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.015	0.985	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.015	0.985	0.000
I24.8 Other forms of acute ischaemic heart disease	0.015	0.985	0.000
M25.39 Other instability of joint (Site unspecified)	0.015	0.985	0.000
M25.38 Other instability of joint (Other)	0.015	0.985	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.015	0.985	0.000
M25.32 Other instability of joint (Upper arm)	0.015	0.985	0.000
M25.30 Other instability of joint (Multiple sites)	0.015	0.985	0.000
M25.33 Other instability of joint (Forearm)	0.015	0.985	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.014	0.985	0.000
M25.88 Other specified joint disorders (Other)	0.014	0.986	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.014	0.986	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.014	0.986	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.014	0.986	0.000
M47.2 Other spondylosis with radiculopathy	0.014	0.986	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.014	0.986	0.000
M47.1 Other spondylosis with myelopathy	0.013	0.987	0.000
M47.84 Other spondylosis (Thoracic region)	0.013	0.987	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.987	0.013
Z47.8 Other specified orthopaedic follow-up care	0.013	0.987	0.000
M25.34 Other instability of joint (Hand)	0.012	0.987	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.012	0.987	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.012	0.988	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.000	0.988	0.012
M22 Disorders of patella	0.012	0.988	0.000
M25.71 Osteophyte (Shoulder region)	0.012	0.988	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.012	0.988	0.000
E66.9 Obesity, unspecified	0.012	0.988	0.000
M47.82 Other spondylosis (Cervical region)	0.012	0.988	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.012	0.988	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.011	0.988	0.000
M47.89 Other spondylosis (Site unspecified)	0.011	0.989	0.000
M22.0 Recurrent dislocation of patella	0.011	0.989	0.000
M45-M49 Spondylopathies	0.011	0.989	0.000
M20-M25 Other joint disorders	0.011	0.989	0.000
M25.72 Osteophyte (Upper arm)	0.010	0.989	0.000
M79.67 Pain in limb (Ankle and foot)	0.010	0.990	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.010	0.990	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.010	0.990	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.010	0.990	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.010	0.990	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.010	0.990	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.010	0.990	0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.010	0.990	0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.010	0.990	0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.010	0.990	0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.010	0.990	0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.010	0.990	0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.010	0.990	0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.010	0.990	0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.010	0.990	0.000
M46 Other inflammatory spondylopathies	0.010	0.990	0.000
M22.8 Other disorders of patella	0.009	0.991	0.000
I89.0 Lymphoedema, not elsewhere classified	0.009	0.991	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.009	0.991	0.000
M25.37 Other instability of joint (Ankle and foot)	0.009	0.991	0.000
M22.9 Disorder of patella, unspecified	0.009	0.991	0.000
M32 Systemic lupus erythematosus	0.009	0.991	0.000
M22.1 Recurrent subluxation of patella	0.009	0.991	0.000
M24.07 Loose body in joint (Ankle and foot)	0.009	0.991	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.009	0.991	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.009	0.991	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.009	0.991	0.000
M47.9 Spondylosis, unspecified	0.009	0.991	0.000
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)	0.008	0.991	0.000
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)	0.008	0.991	0.000
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)	0.008	0.991	0.000
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)	0.008	0.991	0.000
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)	0.008	0.991	0.000
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)	0.008	0.991	0.000
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)	0.008	0.991	0.000
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)	0.008	0.991	0.000
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)	0.008	0.991	0.000
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)	0.008	0.991	0.000
M16.0 Primary coxarthrosis, bilateral	0.008	0.992	0.000
M30 Polyarteritis nodosa and related conditions	0.008	0.992	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.008	0.992	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.008	0.992	0.000
M24 Other specific joint derangements	0.008	0.992	0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.008	0.992	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.008	0.992	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.008	0.992	0.000
M16 Coxarthrosis [arthrosis of hip]	0.008	0.992	0.000
E66 Obesity	0.008	0.992	0.000
M17.9 Gonarthrosis, unspecified	0.008	0.992	0.000
M15-M19 Arthrosis	0.008	0.992	0.000
M46.4 Discitis, unspecified	0.008	0.992	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.008	0.992	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.008	0.992	0.000
M48 Other spondylopathies	0.008	0.992	0.000
R47 Speech disturbances, not elsewhere classified	0.000	0.992	0.008
K12.1 Other forms of stomatitis	0.008	0.992	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.008	0.992	0.000
M22.3 Other derangements of patella	0.008	0.992	0.000
M24.0 Loose body in joint	0.008	0.992	0.000
M24.1 Other articular cartilage disorders	0.008	0.992	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.008	0.992	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.008	0.992	0.000
M16.7 Other secondary coxarthrosis	0.007	0.993	0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral	0.007	0.993	0.000
M17 Gonarthrosis [arthrosis of knee]	0.007	0.993	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.007	0.993	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.007	0.993	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.007	0.993	0.000
M21 Other acquired deformities of limbs	0.007	0.993	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.007	0.993	0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.000	0.993	0.007
M86-M90 Other osteopathies	0.007	0.993	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.007	0.993	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.007	0.993	0.000
Z42 Follow-up care involving plastic surgery	0.000	0.993	0.007
M43.1 Spondylolisthesis	0.007	0.993	0.000
M46.8 Other specified inflammatory spondylopathies	0.007	0.993	0.000
M46.5 Other infective spondylopathies	0.007	0.993	0.000
M49 Spondylopathies in diseases classified elsewhere	0.007	0.993	0.000
M16.3 Other dysplastic coxarthrosis	0.007	0.993	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.007	0.993	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.007	0.993	0.000
M46.0 Spinal enthesopathy	0.007	0.993	0.000
E66.0 Obesity due to excess calories	0.007	0.993	0.000
R47.0 Dysphasia and aphasia	0.000	0.993	0.007
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.007	0.993	0.000
M46.2 Osteomyelitis of vertebra	0.007	0.993	0.000
M00-M03 Infectious arthropathies	0.007	0.993	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.007	0.993	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.007	0.993	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.007	0.993	0.000
M40-M43 Deforming dorsopathies	0.007	0.993	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.007	0.993	0.000
M32.8 Other forms of systemic lupus erythematosus	0.007	0.993	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.007	0.993	0.000
M15 Polyarthrosis	0.007	0.993	0.000
M43 Other deforming dorsopathies	0.007	0.993	0.000
M91-M94 Chondropathies	0.007	0.993	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.007	0.993	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.007	0.993	0.000
M24.04 Loose body in joint (Hand)	0.007	0.993	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.006	0.993	0.000
M24.7 Protrusio acetabuli	0.007	0.993	0.000
M46.42 Discitis, unspecified (Cervical region)	0.006	0.993	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.007	0.993	0.000
M35 Other systemic involvement of connective tissue	0.007	0.993	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.007	0.993	0.000
M18 Arthrosis of first carpometacarpal joint	0.007	0.993	0.000
M21.7 Unequal limb length (acquired)	0.006	0.994	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.006	0.994	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.006	0.994	0.000
M16.5 Other posttraumatic coxarthrosis	0.006	0.994	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.006	0.994	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.006	0.994	0.000
E66.8 Other obesity	0.006	0.994	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.006	0.994	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.006	0.994	0.000
M30.2 Juvenile polyarteritis	0.006	0.994	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.006	0.994	0.000
M02 Reactive arthropathies	0.006	0.994	0.000
M21.6 Other acquired deformities of ankle and foot	0.006	0.994	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.006	0.994	0.000
M36.3 Arthropathy in other blood disorders	0.006	0.994	0.000
M36.2 Haemophilic arthropathy	0.006	0.994	0.000
M36.1 Arthropathy in neoplastic disease	0.006	0.994	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.006	0.994	0.000
G96.0 Cerebrospinal fluid leak	0.006	0.994	0.000
M48.8 Other specified spondylopathies	0.006	0.994	0.000
M88 Paget's disease of bone [osteitis deformans]	0.006	0.994	0.000
M24.9 Joint derangement, unspecified	0.006	0.994	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.006	0.994	0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.006	0.994	0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar	0.006	0.994	0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar	0.006	0.994	0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic	0.006	0.994	0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic	0.006	0.994	0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical	0.006	0.994	0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl	0.006	0.994	0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site	0.006	0.994	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.006	0.994	0.000
E66.1 Drug-induced obesity	0.006	0.994	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.006	0.994	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.006	0.994	0.000
M46.49 Discitis, unspecified (Site unspecified)	0.006	0.994	0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)	0.006	0.994	0.000
M46.45 Discitis, unspecified (Thoracolumbar region)	0.006	0.994	0.000
M46.43 Discitis, unspecified (Cervicothoracic region)	0.006	0.994	0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)	0.006	0.994	0.000
M46.40 Discitis, unspecified (Multiple sites in spine)	0.006	0.994	0.000
M30.0 Polyarteritis nodosa	0.006	0.994	0.000
M48.9 Spondylopathy, unspecified	0.006	0.994	0.000
M43.12 Spondylolisthesis (Cervical region)	0.006	0.994	0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.006	0.994	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.006	0.994	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.006	0.994	0.000
M48.4 Fatigue fracture of vertebra	0.006	0.994	0.000
M48.3 Traumatic spondylopathy	0.006	0.994	0.000
M48.2 Kissing spine	0.006	0.994	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.006	0.994	0.000
M87 Osteonecrosis	0.006	0.994	0.000
M15.1 Heberden's nodes (with arthropathy)	0.006	0.994	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.006	0.994	0.000
M48.0 Spinal stenosis	0.006	0.994	0.000
M89 Other disorders of bone	0.006	0.994	0.000
M86 Osteomyelitis	0.006	0.994	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.006	0.994	0.000
M21.8 Other specified acquired deformities of limbs	0.006	0.994	0.000
M35.0 Sicca syndrome [Sjogren]	0.006	0.994	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.006	0.994	0.000
M60-M63 Disorders of muscles	0.005	0.994	0.000
M24.09 Loose body in joint (Site unspecified)	0.006	0.994	0.000
M24.08 Loose body in joint (Other)	0.006	0.994	0.000
M24.06 Loose body in joint-Lower leg	0.006	0.994	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.006	0.994	0.000
M24.00 Loose body in joint (Multiple sites)	0.006	0.994	0.000
M65.34 Trigger finger-Hand	0.000	0.994	0.006
M46.47 Discitis, unspecified (Lumbosacral region)	0.006	0.994	0.000
M15.3 Secondary multiple arthrosis	0.006	0.994	0.000
U80.1 Methicillin resistant agent	0.006	0.994	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.006	0.994	0.000
M24.18 Other articular cartilage disorders (Other)	0.006	0.994	0.000
M24.14 Other articular cartilage disorders (Hand)	0.006	0.994	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.006	0.994	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.006	0.994	0.000
M89.5 Osteolysis	0.006	0.994	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.006	0.994	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.006	0.994	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.006	0.994	0.000
M35.8 Other specified systemic involvement of connective tissue	0.006	0.994	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.006	0.994	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.006	0.994	0.000
Z42.9 Follow-up care involving plastic surgery, unspecified	0.000	0.994	0.006
M92 Other juvenile osteochondrosis	0.006	0.994	0.000
U80 Agent resistant to penicillin and related antibiotics	0.006	0.994	0.000
M21.0 Valgus deformity, not elsewhere classified	0.006	0.994	0.000
Z42.8 Follow-up care involving plastic surgery of other body part	0.000	0.994	0.005
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.005	0.994	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.005	0.994	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.005	0.994	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.005	0.994	0.000
M43.2 Other fusion of spine	0.005	0.994	0.000
M94 Other disorders of cartilage	0.006	0.994	0.000
M34 Systemic sclerosis	0.005	0.994	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.005	0.994	0.000
M89.0 Algoneurodystrophy	0.005	0.994	0.000
M02.9 Reactive arthopathy, unspecified	0.005	0.995	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.005	0.995	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.005	0.995	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.005	0.995	0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.005	0.995	0.000
M43.15 Spondylolisthesis (Thoracolumbar region)	0.005	0.995	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.005	0.995	0.000
M43.13 Spondylolisthesis (Cervicothoracic region)	0.005	0.995	0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.005	0.995	0.000
M43.10 Spondylolisthesis (Multiple sites in spine)	0.005	0.995	0.000
M46.59 Other infective spondylopathies (Site unspecified)	0.005	0.995	0.000
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)	0.005	0.995	0.000
M46.57 Other infective spondylopathies (Lumbosacral region)	0.005	0.995	0.000
M46.56 Other infective spondylopathies (Lumbar region)	0.005	0.995	0.000
M46.55 Other infective spondylopathies (Thoracolumbar region)	0.005	0.995	0.000
M46.54 Other infective spondylopathies (Thoracic region)	0.005	0.995	0.000
M46.53 Other infective spondylopathies (Cervicothoracic region)	0.005	0.995	0.000
M46.52 Other infective spondylopathies (Cervical region)	0.005	0.995	0.000
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)	0.005	0.995	0.000
M46.50 Other infective spondylopathies (Multiple sites in spine)	0.005	0.995	0.000
M46.89 Other specified inflammatory spondylopathies (Site unspecified)	0.005	0.995	0.000
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)	0.005	0.995	0.000
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)	0.005	0.995	0.000
M46.86 Other specified inflammatory spondylopathies (Lumbar region)	0.005	0.995	0.000
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)	0.005	0.995	0.000
M46.84 Other specified inflammatory spondylopathies (Thoracic region)	0.005	0.995	0.000
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)	0.005	0.995	0.000
M46.82 Other specified inflammatory spondylopathies (Cervical region)	0.005	0.995	0.000
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)	0.005	0.995	0.000
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)	0.005	0.995	0.000
M02.3 Reiter's disease	0.005	0.995	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.005	0.995	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.005	0.995	0.000
M49.4 Neuropathic spondylopathy	0.005	0.995	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
M49.2 Enterobacterial spondylitis	0.005	0.995	0.000
M49.1 Brucella spondylitis	0.005	0.995	0.000
M49.0 Tuberculosis of spine	0.005	0.995	0.000
M17.0 Primary gonarthrosis, bilateral	0.005	0.995	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.005	0.995	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.005	0.995	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.005	0.995	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.005	0.995	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.005	0.995	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.005	0.995	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.005	0.995	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.005	0.995	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.005	0.995	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.005	0.995	0.000
M46.09 Spinal enthesopathy (Site unspecified)	0.005	0.995	0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)	0.005	0.995	0.000
M46.07 Spinal enthesopathy (Lumbosacral region)	0.005	0.995	0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)	0.005	0.995	0.000
M46.04 Spinal enthesopathy (Thoracic region)	0.005	0.995	0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)	0.005	0.995	0.000
M46.02 Spinal enthesopathy (Cervical region)	0.005	0.995	0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)	0.005	0.995	0.000
M46.00 Spinal enthesopathy (Multiple sites in spine)	0.005	0.995	0.000
R47.1 Dysarthria and anarthria	0.000	0.995	0.005
M46.44 Discitis, unspecified (Thoracic region)	0.005	0.995	0.000
M15.8 Other polyarthrosis	0.005	0.995	0.000
M46.29 Osteomyelitis of vertebra (Site unspecified)	0.005	0.995	0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)	0.005	0.995	0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)	0.005	0.995	0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)	0.005	0.995	0.000
M46.24 Osteomyelitis of vertebra (Thoracic region)	0.005	0.995	0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)	0.005	0.995	0.000
M46.22 Osteomyelitis of vertebra (Cervical region)	0.005	0.995	0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)	0.005	0.995	0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)	0.005	0.995	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.005	0.995	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.005	0.995	0.000
M88.9 Paget's disease of bone, unspecified	0.005	0.995	0.000
M15.4 Erosive (osteo)arthrosis	0.005	0.995	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.005	0.995	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.005	0.995	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.005	0.995	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.005	0.995	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.005	0.995	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.005	0.995	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.005	0.995	0.000
M46.06 Spinal enthesopathy (Lumbar region)	0.005	0.995	0.000
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)	0.005	0.995	0.000
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)	0.005	0.995	0.000
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)	0.005	0.995	0.000
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)	0.005	0.995	0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)	0.005	0.995	0.000
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)	0.005	0.995	0.000
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)	0.005	0.995	0.000
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)	0.005	0.995	0.000
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)	0.005	0.995	0.000
M21.2 Flexion deformity	0.005	0.995	0.000
M42 Spinal osteochondrosis	0.005	0.995	0.000
M13.9 Arthritis, unspecified	0.005	0.995	0.000
M88.8 Paget's disease of other bones	0.005	0.995	0.000
M94.8 Other specified disorders of cartilage	0.005	0.995	0.000
M33 Dermatopolymyositis	0.005	0.995	0.000
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.005	0.995	0.000
M15.0 Primary generalised (osteo)arthrosis	0.005	0.995	0.000
M43.9 Deforming dorsopathy, unspecified	0.005	0.995	0.000
M43.8 Other specified deforming dorsopathies	0.005	0.995	0.000
M43.5 Other recurrent vertebral subluxation	0.005	0.995	0.000
M43.4 Other recurrent atlantoaxial subluxation	0.005	0.995	0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.005	0.995	0.000
M17.5 Other secondary gonarthrosis	0.005	0.995	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.005	0.995	0.000
M45 Ankylosing spondylitis	0.005	0.995	0.000
M17.3 Other posttraumatic gonarthrosis	0.005	0.995	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.000	0.995	0.005
M17.4 Other secondary gonarthrosis, bilateral	0.005	0.995	0.000
M00 Pyogenic arthritis	0.005	0.995	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.005	0.995	0.000
M89.03 Algoneurodystrophy (Forearm)	0.005	0.995	0.000
M21.9 Acquired deformity of limb, unspecified	0.005	0.995	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.005	0.995	0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)	0.005	0.995	0.000
M35.7 Hypermobility syndrome	0.005	0.995	0.000
M24.79 Protrusio acetabuli-Site unspec	0.005	0.995	0.000
M24.78 Protrusio acetabuli-Other	0.005	0.995	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.005	0.995	0.000
M24.76 Protrusio acetabuli-Lower leg	0.005	0.995	0.000
M24.74 Protrusio acetabuli-Hand	0.005	0.995	0.000
M24.73 Protrusio acetabuli-Forearm	0.005	0.995	0.000
M24.72 Protrusio acetabuli-Upper arm	0.005	0.995	0.000
M24.71 Protrusio acetabuli-Shldr region	0.005	0.995	0.000
M24.70 Protrusio acetabuli-Mult sites	0.005	0.995	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.005	0.995	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.005	0.995	0.000
M35.5 Multifocal fibrosclerosis	0.005	0.995	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.005	0.995	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.005	0.995	0.000
M48.09 Spinal stenosis (Site unspecified)	0.005	0.995	0.000
M87.1 Osteonecrosis due to drugs	0.005	0.995	0.000
M86.6 Other chronic osteomyelitis	0.005	0.995	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.005	0.995	0.000
M60 Myositis	0.005	0.995	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.005	0.995	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.005	0.995	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.005	0.995	0.000
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)	0.005	0.995	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.005	0.995	0.000
M87.3 Other secondary osteonecrosis	0.005	0.995	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.005	0.995	0.000
M21.78 Unequal limb length (acquired)-Other	0.005	0.995	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.005	0.995	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.005	0.995	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.005	0.995	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.005	0.995	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.005	0.995	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.005	0.995	0.000
M24.5 Contracture of joint	0.005	0.995	0.000
M21.3 Wrist or foot drop (acquired)	0.005	0.995	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.005	0.995	0.000
M24.01 Loose body in joint (Shoulder region)	0.005	0.995	0.000
M43.0 Spondylolysis	0.005	0.995	0.000
M31 Other necrotising vasculopathies	0.005	0.995	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.005	0.995	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.005	0.995	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.005	0.995	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.005	0.995	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.005	0.995	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.005	0.995	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.005	0.995	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.005	0.995	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.005	0.995	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.005	0.995	0.000
M02.8 Other reactive arthropathies	0.005	0.995	0.000
M02.2 Postimmunisation arthropathy	0.005	0.995	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations