TreeWAS – Variant ID: rs707040

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K74.6 Other and unspecified cirrhosis of liver	0.118	0.882	0.000
K74 Fibrosis and cirrhosis of liver	0.116	0.884	0.000
K74.5 Biliary cirrhosis, unspecified	0.104	0.895	0.000
K74.3 Primary biliary cirrhosis	0.102	0.898	0.000
K70-K77 Diseases of liver	0.094	0.906	0.000
K74.0 Hepatic fibrosis	0.094	0.906	0.000
K76.6 Portal hypertension	0.089	0.911	0.000
K76 Other diseases of liver	0.088	0.912	0.000
K74.1 Hepatic sclerosis	0.087	0.913	0.000
K74.4 Secondary biliary cirrhosis	0.084	0.916	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.084	0.916	0.000
K73 Chronic hepatitis, not elsewhere classified	0.077	0.923	0.000
K72 Hepatic failure, not elsewhere classified	0.075	0.925	0.000
K70 Alcoholic liver disease	0.074	0.926	0.000
K71 Toxic liver disease	0.074	0.926	0.000
K77 Liver disorders in diseases classified elsewhere	0.073	0.927	0.000
K76.1 Chronic passive congestion of liver	0.070	0.930	0.000
K76.7 Hepatorenal syndrome	0.067	0.933	0.000
K70.3 Alcoholic cirrhosis of liver	0.064	0.936	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.064	0.936	0.000
K76.5 Hepatic veno-occlusive disease	0.063	0.937	0.000
K76.4 Peliosis hepatis	0.063	0.937	0.000
K76.3 Infarction of liver	0.063	0.937	0.000
K76.2 Central haemorrhagic necrosis of liver	0.063	0.937	0.000
K70.1 Alcoholic hepatitis	0.063	0.937	0.000
K72.9 Hepatic failure, unspecified	0.061	0.939	0.000
K72.1 Chronic hepatic failure	0.061	0.939	0.000
K71.0 Toxic liver disease with cholestasis	0.059	0.940	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.058	0.942	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.056	0.944	0.000
K73.9 Chronic hepatitis, unspecified	0.056	0.944	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.056	0.944	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.055	0.945	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.055	0.945	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.055	0.945	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.054	0.946	0.000
K71.9 Toxic liver disease, unspecified	0.053	0.947	0.000
K71.8 Toxic liver disease with other disorders of liver	0.053	0.947	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.053	0.947	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.053	0.947	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.053	0.947	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.053	0.947	0.000
K71.2 Toxic liver disease with acute hepatitis	0.053	0.947	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.053	0.947	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.052	0.947	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.050	0.950	0.000
K70.4 Alcoholic hepatic failure	0.049	0.951	0.000
K70.9 Alcoholic liver disease, unspecified	0.049	0.951	0.000
K76.9 Liver disease, unspecified	0.047	0.953	0.000
K72.0 Acute and subacute hepatic failure	0.043	0.956	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.957	0.043
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.958	0.042
F31 Bipolar affective disorder	0.000	0.958	0.042
K76.8 Other specified diseases of liver	0.039	0.961	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.962	0.038
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.967	0.033
K70.0 Alcoholic fatty liver	0.032	0.967	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.968	0.032
F31.9 Bipolar affective disorder, unspecified	0.000	0.969	0.031
F31.8 Other bipolar affective disorders	0.000	0.970	0.030
D72 Other disorders of white blood cells	0.030	0.970	0.000
D72.1 Eosinophilia	0.030	0.970	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.029	0.971	0.000
D73 Diseases of spleen	0.028	0.972	0.000
D76.3 Other histiocytosis syndromes	0.028	0.972	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.972	0.028
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.028	0.972	0.000
D72.8 Other specified disorders of white blood cells	0.027	0.973	0.000
D73.0 Hyposplenism	0.027	0.973	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.975	0.025
D73.8 Other diseases of spleen	0.025	0.975	0.000
D75 Other diseases of blood and blood-forming organs	0.024	0.976	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.977	0.023
D73.5 Infarction of spleen	0.022	0.978	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.022	0.978	0.000
D72.9 Disorder of white blood cells, unspecified	0.022	0.978	0.000
D72.0 Genetic anomalies of leukocytes	0.022	0.978	0.000
D73.3 Abscess of spleen	0.022	0.978	0.000
D73.4 Cyst of spleen	0.021	0.978	0.000
D74 Methaemoglobinaemia	0.021	0.979	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.021	0.979	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.021	0.979	0.000
D73.2 Chronic congestive splenomegaly	0.020	0.979	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.020	0.980	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.020	0.980	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.020	0.980	0.000
D73.9 Disease of spleen, unspecified	0.019	0.981	0.000
D75.1 Secondary polycythaemia	0.019	0.981	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.019	0.981	0.000
D73.1 Hypersplenism	0.018	0.982	0.000
D75.2 Essential thrombocytosis	0.018	0.982	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.016	0.984	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.016	0.984	0.000
D74.9 Methaemoglobinaemia, unspecified	0.015	0.985	0.000
D74.8 Other methaemoglobinaemias	0.015	0.985	0.000
D74.0 Congenital methaemoglobinaemia	0.015	0.985	0.000
F30-F39 Mood [affective] disorders	0.000	0.986	0.014
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.014	0.986	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.014	0.986	0.000
K75 Other inflammatory liver diseases	0.014	0.986	0.000
F30 Manic episode	0.000	0.986	0.014
D75.9 Disease of blood and blood-forming organs, unspecified	0.014	0.986	0.000
F30.9 Manic episode, unspecified	0.000	0.986	0.013
D75.0 Familial erythrocytosis	0.013	0.987	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.012	0.987	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.012	0.988	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
F33 Recurrent depressive disorder	0.000	0.989	0.011
F30.2 Mania with psychotic symptoms	0.000	0.989	0.011
F30.1 Mania without psychotic symptoms	0.000	0.989	0.011
F38 Other mood [affective] disorders	0.000	0.990	0.010
K75.2 Nonspecific reactive hepatitis	0.010	0.990	0.000
K75.1 Phlebitis of portal vein	0.010	0.990	0.000
F30.8 Other manic episodes	0.000	0.990	0.010
F30.0 Hypomania	0.000	0.990	0.010
F39 Unspecified mood [affective] disorder	0.000	0.990	0.010
K75.8 Other specified inflammatory liver diseases	0.009	0.990	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.991	0.009
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.992	0.008
K75.3 Granulomatous hepatitis, not elsewhere classified	0.008	0.992	0.000
M75.3 Calcific tendinitis of shoulder	0.008	0.992	0.000
F34 Persistent mood [affective] disorders	0.000	0.992	0.008
F33.8 Other recurrent depressive disorders	0.000	0.992	0.008
B18.2 Chronic viral hepatitis C	0.008	0.992	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.992	0.008
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.992	0.008
F38.1 Other recurrent mood [affective] disorders	0.000	0.992	0.007
F38.0 Other single mood [affective] disorders	0.000	0.992	0.007
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.992	0.008
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.992	0.008
F38.8 Other specified mood [affective] disorders	0.000	0.992	0.007
K75.9 Inflammatory liver disease, unspecified	0.007	0.993	0.000
K75.4 Autoimmune hepatitis	0.007	0.993	0.000
B18 Chronic viral hepatitis	0.006	0.994	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.994	0.006
F34.8 Other persistent mood [affective] disorders	0.000	0.994	0.006
O94-O99 Other obstetric conditions, not elsewhere classified	0.006	0.994	0.000
F34.0 Cyclothymia	0.000	0.994	0.005
M95.0 Acquired deformity of nose	0.005	0.995	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.005	0.995	0.000
C83.3 Large cell (diffuse)	0.000	0.995	0.005
N49.2 Inflammatory disorders of scrotum	0.005	0.995	0.000
F34.1 Dysthymia	0.000	0.995	0.005
T90.9 Sequelae of unspecified injury of head	0.005	0.995	0.000
D86.9 Sarcoidosis, unspecified	0.005	0.995	0.000
B18.9 Chronic viral hepatitis, unspecified	0.005	0.995	0.000
B18.8 Other chronic viral hepatitis	0.005	0.995	0.000
B18.0 Chronic viral hepatitis B with delta-agent	0.005	0.995	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.995	0.005
C49.2 Connective and soft tissue of lower limb, including hip	0.005	0.995	0.000
O97 Death from sequelae of direct obstetric causes	0.004	0.995	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.004	0.995	0.000
O95 Obstetric death of unspecified cause	0.004	0.995	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.004	0.995	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.004	0.995	0.000
J35.0 Chronic tonsillitis	0.000	0.996	0.004
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
B16 Acute hepatitis B	0.004	0.996	0.000
K75.0 Abscess of liver	0.004	0.996	0.000
B15-B19 Viral hepatitis	0.004	0.996	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.996	0.004
L29.9 Pruritus, unspecified	0.004	0.996	0.000
C49.0 Connective and soft tissue of head, face and neck	0.004	0.996	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.996	0.004
C49 Malignant neoplasm of other connective and soft tissue	0.004	0.996	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.996	0.004
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.000	0.996	0.004
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.996	0.004
C83.1 Small cleaved cell (diffuse)	0.000	0.996	0.004
C49.9 Connective and soft tissue, unspecified	0.004	0.996	0.000
G72.9 Myopathy, unspecified	0.004	0.996	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.996	0.004
D86 Sarcoidosis	0.004	0.996	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.996	0.004
O96.9 Death from unspecified obstetric cause	0.003	0.996	0.000
O96.1 Death from indirect obstetric cause	0.003	0.996	0.000
O96.0 Death from direct obstetric cause	0.003	0.996	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.003	0.996	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.003	0.996	0.000
O97.0 Death from sequelae of direct obstetric cause	0.003	0.996	0.000
C49.5 Connective and soft tissue of pelvis	0.003	0.997	0.000
D45 Polycythaemia vera	0.003	0.997	0.000
C83.7 Burkitt's tumour	0.000	0.997	0.003
B17 Other acute viral hepatitis	0.003	0.997	0.000
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.003	0.997	0.000
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.003	0.997	0.000
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.003	0.997	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.003	0.997	0.000
D80-D89 Certain disorders involving the immune mechanism	0.003	0.997	0.000
K50.0 Crohn's disease of small intestine	0.003	0.997	0.000
D59.1 Other autoimmune haemolytic anaemias	0.000	0.997	0.003
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.003	0.997	0.000
H02.3 Blepharochalasis	0.003	0.997	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.997	0.003
B19 Unspecified viral hepatitis	0.003	0.997	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.003	0.997	0.000
I08.0 Disorders of both mitral and aortic valves	0.003	0.997	0.000
L05.0 Pilonidal cyst with abscess	0.003	0.997	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.003	0.997	0.000
D86.8 Sarcoidosis of other and combined sites	0.003	0.997	0.000
C83.6 Undifferentiated (diffuse)	0.000	0.997	0.003
C83.4 Immunoblastic (diffuse)	0.000	0.997	0.003
C83.2 Mixed small and large cell (diffuse)	0.000	0.997	0.003
T90 Sequelae of injuries of head	0.003	0.997	0.000
D84.9 Immunodeficiency, unspecified	0.003	0.997	0.000
B15 Acute hepatitis A	0.003	0.997	0.000
D84 Other immunodeficiencies	0.003	0.997	0.000
C83.0 Small cell (diffuse)	0.000	0.997	0.003
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.003	0.997	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.003	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.003	0.997	0.000
D80 Immunodeficiency with predominantly antibody defects	0.003	0.997	0.000
B17.1 Acute hepatitis C	0.003	0.997	0.000
M95.1 Cauliflower ear	0.003	0.997	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.003	0.997	0.000
C49.4 Connective and soft tissue of abdomen	0.003	0.997	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.003	0.997	0.000
H35.3 Degeneration of macula and posterior pole	0.000	0.997	0.003
D86.3 Sarcoidosis of skin	0.003	0.997	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.997	0.003
B37.3 Candidiasis of vulva and vagina	0.000	0.997	0.003
D82 Immunodeficiency associated with other major defects	0.003	0.997	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.003	0.997	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
S91.1 Open wound of toe(s) without damage to nail	0.003	0.997	0.000
F52.2 Failure of genital response	0.003	0.997	0.000
B17.9 Acute viral hepatitis, unspecified	0.002	0.997	0.000
B17.2 Acute hepatitis E	0.002	0.997	0.000
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.002	0.997	0.000
N49.8 Inflammatory disorders of other specified male genital organs	0.003	0.997	0.000
C83.5 Lymphoblastic (diffuse)	0.000	0.997	0.002
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.002	0.997	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.002	0.997	0.000
M95.5 Acquired deformity of pelvis	0.002	0.997	0.000
I97.1 Other functional disturbances following cardiac surgery	0.003	0.997	0.000
N81.9 Female genital prolapse, unspecified	0.003	0.997	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.002	0.997	0.000
D81 Combined immunodeficiencies	0.002	0.997	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.997	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.002	0.997	0.000
D59 Acquired haemolytic anaemia	0.001	0.997	0.002
M95.2 Other acquired deformity of head	0.002	0.997	0.000
B17.8 Other specified acute viral hepatitis	0.002	0.997	0.000
M95.4 Acquired deformity of chest and rib	0.002	0.997	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.002	0.997	0.000
N49.0 Inflammatory disorders of seminal vesicle	0.002	0.997	0.000
T79.8 Other early complications of trauma	0.002	0.997	0.000
T90.8 Sequelae of other specified injuries of head	0.002	0.998	0.000
B19.0 Unspecified viral hepatitis with coma	0.002	0.998	0.000
C49.3 Connective and soft tissue of thorax	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.002	0.998	0.000
T90.3 Sequelae of injury of cranial nerves	0.002	0.998	0.000
B15.0 Hepatitis A with hepatic coma	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
D84.1 Defects in the complement system	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
M95.3 Acquired deformity of neck	0.002	0.998	0.000
T90.1 Sequelae of open wound of head	0.002	0.998	0.000
D55-D59 Haemolytic anaemias	0.002	0.998	0.001
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
K50.8 Other Crohn's disease	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
T90.5 Sequelae of intracranial injury	0.002	0.998	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.001
T90.0 Sequelae of superficial injury of head	0.002	0.998	0.000
S91 Open wound of ankle and foot	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.002
B19.9 Unspecified viral hepatitis without coma	0.002	0.998	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
K50 Crohn's disease [regional enteritis]	0.002	0.998	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
B35.3 Tinea pedis	0.002	0.998	0.000
T45.5 Anticoagulants	0.002	0.998	0.000
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.002	0.998	0.000
B15.9 Hepatitis A without hepatic coma	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.998	0.002
S91.0 Open wound of ankle	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.002	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.001	0.998	0.001
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.001	0.998	0.001
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.001	0.998	0.001
D59.4 Other nonautoimmune haemolytic anaemias	0.001	0.998	0.001
D59.3 Haemolytic-uraemic syndrome	0.001	0.998	0.001
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.001	0.998	0.001
D59.0 Drug-induced autoimmune haemolytic anaemia	0.001	0.998	0.001
T79.6 Traumatic ischaemia of muscle	0.002	0.998	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.000	0.998	0.002
N60.0 Solitary cyst of breast	0.000	0.998	0.002
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
K04.8 Radicular cyst	0.002	0.998	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.002
I95.9 Hypotension, unspecified	0.002	0.998	0.000
D58.0 Hereditary spherocytosis	0.002	0.998	0.000
D57 Sickle-cell disorders	0.001	0.998	0.001
D55 Anaemia due to enzyme disorders	0.001	0.998	0.001
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.998	0.002
C71.9 Brain, unspecified	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.002	0.998	0.000
K50.1 Crohn's disease of large intestine	0.002	0.998	0.000
K80.4 Calculus of bile duct with cholecystitis	0.000	0.998	0.002
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.998	0.002
Z12.8 Special screening examination for neoplasm of other sites	0.002	0.998	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
T42.4 Benzodiazepines	0.002	0.998	0.000
I97.0 Postcardiotomy syndrome	0.002	0.998	0.000
O03.9 Complete or unspecified, without complication	0.002	0.998	0.000
T68 Hypothermia	0.000	0.998	0.002
H40.1 Primary open-angle glaucoma	0.002	0.998	0.000
N50.1 Vascular disorders of male genital organs	0.000	0.998	0.002
S79.9 Unspecified injury of hip and thigh	0.000	0.998	0.002
T90.4 Sequelae of injury of eye and orbit	0.002	0.998	0.000
D56 Thalassaemia	0.001	0.998	0.001
I97.2 Postmastectomy lymphoedema syndrome	0.002	0.998	0.000
T79.9 Unspecified early complication of trauma	0.002	0.998	0.000
T79.4 Traumatic shock	0.002	0.998	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.002	0.998	0.000
T79.1 Fat embolism (traumatic)	0.002	0.998	0.000
T79.0 Air embolism (traumatic)	0.002	0.998	0.000
Z58.1 Exposure to air pollution	0.002	0.998	0.000
S71.1 Open wound of thigh	0.000	0.998	0.002
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.000	0.998	0.002
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.998	0.002
K50.9 Crohn's disease, unspecified	0.002	0.998	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.001	0.998	0.000
D58.1 Hereditary elliptocytosis	0.001	0.998	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.001	0.998	0.000
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
Z71.9 Counselling, unspecified	0.002	0.998	0.000
D58.2 Other haemoglobinopathies	0.001	0.998	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.002	0.998	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.001	0.998	0.001
D55.8 Other anaemias due to enzyme disorders	0.001	0.998	0.001
D55.3 Anaemia due to disorders of nucleotide metabolism	0.001	0.998	0.001
D55.2 Anaemia due to disorders of glycolytic enzymes	0.001	0.998	0.001
D55.1 Anaemia due to other disorders of glutathione metabolism	0.001	0.998	0.001
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.001	0.998	0.001
D57.8 Other sickle-cell disorders	0.001	0.998	0.001
D57.3 Sickle-cell trait	0.001	0.998	0.001
D57.2 Double heterozygous sickling disorders	0.001	0.998	0.001
D57.1 Sickle-cell anaemia without crisis	0.001	0.998	0.001
D57.0 Sickle-cell anaemia with crisis	0.001	0.998	0.001
I83.1 Varicose veins of lower extremities with inflammation	0.002	0.998	0.000
K66.0 Peritoneal adhesions	0.000	0.998	0.002
Z93.5 Cystostomy status	0.000	0.998	0.002
K00.6 Disturbances in tooth eruption	0.002	0.998	0.000
S70.8 Other superficial injuries of hip and thigh	0.000	0.998	0.002
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.998	0.002
M99.53 Intervertebral disc stenosis of neural canal (Lumbar region)	0.002	0.998	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.002	0.998	0.000
K07.6 Temporomandibular joint disorders	0.000	0.998	0.002
L85.8 Other specified epidermal thickening	0.002	0.998	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
M99.5 Intervertebral disk stenosis of neural canal	0.002	0.998	0.000
T79.5 Traumatic anuria	0.001	0.998	0.000
T91.1 Sequelae of fracture of spine	0.002	0.998	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.002	0.998	0.000
Z93.6 Other artificial openings of urinary tract status	0.000	0.998	0.002
H05.0 Acute inflammation of orbit	0.000	0.998	0.002
R54 Senility	0.002	0.998	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.001	0.998	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.001	0.998	0.000
F52.7 Excessive sexual drive	0.001	0.998	0.000
F52.6 Nonorganic dyspareunia	0.001	0.998	0.000
F52.5 Nonorganic vaginismus	0.001	0.998	0.000
F52.4 Premature ejaculation	0.001	0.998	0.000
F52.3 Orgasmic dysfunction	0.001	0.998	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.001	0.998	0.000
F52.0 Lack or loss of sexual desire	0.001	0.998	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.001	0.998	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.998	0.002
N13.6 Pyonephrosis	0.002	0.998	0.000
D60-D64 Aplastic and other anaemias	0.002	0.998	0.000
M99.50 Intervertebral disc stenosis of neural canal (Head region)	0.001	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.998	0.002
D56.9 Thalassaemia, unspecified	0.001	0.998	0.001
D56.8 Other thalassaemias	0.001	0.998	0.001
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.001	0.998	0.001
D56.2 Delta-beta thalassaemia	0.001	0.998	0.001
D56.0 Alpha thalassaemia	0.001	0.998	0.001
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.002	0.998	0.000
O81.4 Vacuum extractor delivery	0.002	0.998	0.000
S70 Superficial injury of hip and thigh	0.000	0.998	0.002
M25.51 Pain in joint (Shoulder region)	0.000	0.998	0.002
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.998	0.002
C07 Malignant neoplasm of parotid gland	0.002	0.998	0.000
S79 Other and unspecified injuries of hip and thigh	0.000	0.998	0.002
T91.3 Sequelae of injury of spinal cord	0.002	0.998	0.000
Z36 Antenatal screening	0.000	0.998	0.002
M99 Biomechanical lesions, not elsewhere classified	0.001	0.998	0.000
I49.0 Ventricular fibrillation and flutter	0.002	0.998	0.000
S79.8 Other specified injuries of hip and thigh	0.000	0.998	0.001
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.998	0.001
D56.3 Thalassaemia trait	0.001	0.998	0.001
D56.1 Beta thalassaemia	0.001	0.998	0.001
L65.9 Nonscarring hair loss, unspecified	0.000	0.998	0.001
F50.0 Anorexia nervosa	0.001	0.999	0.000
G93.4 Encephalopathy, unspecified	0.001	0.999	0.000
M99.59 Intervertebral disc stenosis of neural canal-Abdomen/other	0.001	0.999	0.000
M99.58 Intervertebral disc stenosis of neural canal-Rib cage	0.001	0.999	0.000
M99.57 Intervertebral disc stenosis of neural canal-Upper extremit	0.001	0.999	0.000
M99.56 Intervertebral disc stenosis of neural canal-Lower extremit	0.001	0.999	0.000
M99.55 Intervertebral disc stenosis of neural canal (Pelvic region)	0.001	0.999	0.000
M99.54 Intervertebral disc stenosis of neural canal (Sacral region)	0.001	0.999	0.000
M99.52 Intervertebral disc stenosis of neural canal (Thoracic region)	0.001	0.999	0.000
M99.51 Intervertebral disc stenosis of neural canal (Cervical region)	0.001	0.999	0.000
D48.5 Skin	0.001	0.999	0.000
G91.1 Obstructive hydrocephalus	0.000	0.999	0.001
G91.0 Communicating hydrocephalus	0.000	0.999	0.001
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.999	0.001
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.001	0.999	0.000
D61.0 Constitutional aplastic anaemia	0.001	0.999	0.000
Z95.3 Presence of xenogenic heart valve	0.001	0.999	0.000
D61 Other aplastic anaemias	0.001	0.999	0.000
K07.4 Malocclusion, unspecified	0.000	0.999	0.001
K29.4 Chronic atrophic gastritis	0.000	0.999	0.001
S71 Open wound of hip and thigh	0.000	0.999	0.001
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.001	0.999	0.000
N91.2 Amenorrhoea, unspecified	0.001	0.999	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.001	0.999	0.000
L05 Pilonidal cyst	0.001	0.999	0.000
D61.9 Aplastic anaemia, unspecified	0.001	0.999	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.000	0.999	0.001
S79.7 Multiple injuries of hip and thigh	0.000	0.999	0.001
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.001	0.999	0.000
T45.0 Antiallergic and antiemetic drugs	0.001	0.999	0.000
T79.7 Traumatic subcutaneous emphysema	0.001	0.999	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.001	0.999	0.000
S82.10 Fracture of upper end of tibia (closed)	0.000	0.999	0.001
C92.0 Acute myeloid leukaemia	0.000	0.999	0.001
F07.2 Postconcussional syndrome	0.001	0.999	0.000
G91.2 Normal-pressure hydrocephalus	0.000	0.999	0.001
M17.5 Other secondary gonarthrosis	0.001	0.999	0.000
M99.9 Biomechanical lesion, unspecified	0.001	0.999	0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina	0.001	0.999	0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina	0.001	0.999	0.000
M99.4 Connective tissue stenosis of neural canal	0.001	0.999	0.000
M99.3 Osseous stenosis of neural canal	0.001	0.999	0.000
M99.2 Subluxation stenosis of neural canal	0.001	0.999	0.000
M99.1 Subluxation complex (vertebral)	0.001	0.999	0.000
M99.0 Segmental and somatic dysfunction	0.001	0.999	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.001	0.999	0.000
Z36.5 Antenatal screening for isoimmunisation	0.000	0.999	0.001
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.999	0.001
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.001	0.999	0.000
M99.8 Other biomechanical lesions	0.001	0.999	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.001	0.999	0.000
S70.1 Contusion of thigh	0.000	0.999	0.001
T93.9 Sequelae of unspecified injury of lower limb	0.001	0.999	0.000
T98 Sequelae of other and unspecified effects of external causes	0.001	0.999	0.000
T91 Sequelae of injuries of neck and trunk	0.001	0.999	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.999	0.001
B37.0 Candidal stomatitis	0.000	0.999	0.001
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.999	0.001
Q76.0 Spina bifida occulta	0.000	0.999	0.001
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.999	0.001
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.001	0.999	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.999	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations